Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Albert Hofman, Ph.D., M.D.

Co-Author

This page shows the publications co-authored by Albert Hofman and Christopher O'Donnell.
Connection Strength

3.712
  1. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nat Commun. 2018 12 03; 9(1):5141.
    View in: PubMed
    Score: 0.203
  2. Genome-wide association studies identify genetic loci for low von Willebrand factor levels. Eur J Hum Genet. 2016 07; 24(7):1096.
    View in: PubMed
    Score: 0.172
  3. Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. PLoS One. 2016; 11(3):e0144997.
    View in: PubMed
    Score: 0.168
  4. Genome-wide association studies identify genetic loci for low von Willebrand factor levels. Eur J Hum Genet. 2016 07; 24(7):1035-40.
    View in: PubMed
    Score: 0.164
  5. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 2013 Sep 17; 128(12):1310-24.
    View in: PubMed
    Score: 0.141
  6. Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation. 2011 Dec 20; 124(25):2855-64.
    View in: PubMed
    Score: 0.125
  7. Genome-wide association analysis identifies multiple loci related to resting heart rate. Hum Mol Genet. 2010 Oct 01; 19(19):3885-94.
    View in: PubMed
    Score: 0.114
  8. Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation. 2010 Mar 30; 121(12):1382-92.
    View in: PubMed
    Score: 0.111
  9. Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet. 2011 Jun 01; 20(11):2273-84.
    View in: PubMed
    Score: 0.059
  10. Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. PLoS One. 2020; 15(11):e0230035.
    View in: PubMed
    Score: 0.058
  11. Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels. Circulation. 2019 01 29; 139(5):620-635.
    View in: PubMed
    Score: 0.051
  12. Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet. 2018 12; 50(12):1755.
    View in: PubMed
    Score: 0.051
  13. A comprehensive evaluation of the genetic architecture of sudden cardiac arrest. Eur Heart J. 2018 11 21; 39(44):3961-3969.
    View in: PubMed
    Score: 0.051
  14. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet. 2018 10; 50(10):1412-1425.
    View in: PubMed
    Score: 0.050
  15. Association of Coronary Artery Calcium Score vs Age With Cardiovascular Risk in Older Adults: An Analysis of Pooled Population-Based Studies. JAMA Cardiol. 2017 09 01; 2(9):986-994.
    View in: PubMed
    Score: 0.047
  16. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 09; 49(9):1373-1384.
    View in: PubMed
    Score: 0.046
  17. Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun. 2017 06 14; 8:15805.
    View in: PubMed
    Score: 0.046
  18. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. PLoS One. 2017; 12(1):e0167742.
    View in: PubMed
    Score: 0.045
  19. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Am J Hum Genet. 2017 Jan 05; 100(1):51-63.
    View in: PubMed
    Score: 0.044
  20. Prevalence and Prognostic Implications of Coronary Artery Calcification in Low-Risk Women: A Meta-analysis. JAMA. 2016 Nov 22; 316(20):2126-2134.
    View in: PubMed
    Score: 0.044
  21. Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis. Circ Cardiovasc Genet. 2016 Dec; 9(6):511-520.
    View in: PubMed
    Score: 0.044
  22. Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. PLoS Genet. 2016 Oct; 12(10):e1006327.
    View in: PubMed
    Score: 0.044
  23. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet. 2016 10; 48(10):1171-1184.
    View in: PubMed
    Score: 0.044
  24. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. J Med Genet. 2016 12; 53(12):835-845.
    View in: PubMed
    Score: 0.043
  25. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. Am J Hum Genet. 2016 09 01; 99(3):785.
    View in: PubMed
    Score: 0.043
  26. Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study. J Am Coll Cardiol. 2016 08 30; 68(9):934-45.
    View in: PubMed
    Score: 0.043
  27. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. Am J Hum Genet. 2016 08 04; 99(2):481-8.
    View in: PubMed
    Score: 0.043
  28. Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. Am J Hum Genet. 2016 Jul 07; 99(1):8-21.
    View in: PubMed
    Score: 0.043
  29. Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. Am J Hum Genet. 2016 Jul 07; 99(1):22-39.
    View in: PubMed
    Score: 0.043
  30. A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. Hum Mol Genet. 2016 Jan 15; 25(2):358-70.
    View in: PubMed
    Score: 0.041
  31. A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nat Genet. 2015 Oct; 47(10):1121-1130.
    View in: PubMed
    Score: 0.041
  32. Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF. Blood. 2015 Sep 10; 126(11):e19-29.
    View in: PubMed
    Score: 0.040
  33. PLD3 variants in population studies. Nature. 2015 Apr 02; 520(7545):E2-3.
    View in: PubMed
    Score: 0.039
  34. A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet. 2015 Mar; 11(3):e1005035.
    View in: PubMed
    Score: 0.039
  35. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nat Commun. 2015 Jan 29; 6:5897.
    View in: PubMed
    Score: 0.039
  36. No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. PLoS One. 2014; 9(12):e111156.
    View in: PubMed
    Score: 0.039
  37. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun. 2014 Oct 28; 5:5068.
    View in: PubMed
    Score: 0.038
  38. Trans-ethnic meta-analysis of white blood cell phenotypes. Hum Mol Genet. 2014 Dec 20; 23(25):6944-60.
    View in: PubMed
    Score: 0.038
  39. Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. Nat Genet. 2014 Aug; 46(8):826-36.
    View in: PubMed
    Score: 0.037
  40. Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. 2014 Aug; 112(4):317-38.
    View in: PubMed
    Score: 0.037
  41. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol. 2014 May; 34(5):1093-101.
    View in: PubMed
    Score: 0.037
  42. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014 Feb 06; 94(2):223-32.
    View in: PubMed
    Score: 0.036
  43. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. Am J Hum Genet. 2014 Feb 06; 94(2):233-45.
    View in: PubMed
    Score: 0.036
  44. Predicting stroke through genetic risk functions: the CHARGE Risk Score Project. Stroke. 2014 Feb; 45(2):403-12.
    View in: PubMed
    Score: 0.036
  45. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr. 2013 Sep; 98(3):668-76.
    View in: PubMed
    Score: 0.035
  46. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet. 2013 Jun; 45(6):621-31.
    View in: PubMed
    Score: 0.034
  47. Genome-wide association study of retinopathy in individuals without diabetes. PLoS One. 2013; 8(2):e54232.
    View in: PubMed
    Score: 0.034
  48. Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk. Circ Cardiovasc Genet. 2012 Dec; 5(6):656-65.
    View in: PubMed
    Score: 0.033
  49. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood. 2012 Dec 06; 120(24):4873-81.
    View in: PubMed
    Score: 0.033
  50. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012; 8(3):e1002607.
    View in: PubMed
    Score: 0.032
  51. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet. 2012 Mar 31; 379(9822):1205-13.
    View in: PubMed
    Score: 0.032
  52. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. PLoS Genet. 2012; 8(2):e1002490.
    View in: PubMed
    Score: 0.032
  53. Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet. 2012 Feb 01; 5(1):100-12.
    View in: PubMed
    Score: 0.031
  54. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet. 2011 Oct 16; 43(11):1131-8.
    View in: PubMed
    Score: 0.031
  55. Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet. 2011 Sep 11; 43(10):940-7.
    View in: PubMed
    Score: 0.031
  56. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 2011 Sep 11; 43(10):1005-11.
    View in: PubMed
    Score: 0.031
  57. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 Sep 11; 478(7367):103-9.
    View in: PubMed
    Score: 0.031
  58. Multiple loci are associated with white blood cell phenotypes. PLoS Genet. 2011 Jun; 7(6):e1002113.
    View in: PubMed
    Score: 0.030
  59. Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals. PLoS Genet. 2011 Jun; 7(6):e1002158.
    View in: PubMed
    Score: 0.030
  60. A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet. 2011 Aug 01; 4(4):403-12.
    View in: PubMed
    Score: 0.030
  61. Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation. 2011 May 03; 123(17):1864-72.
    View in: PubMed
    Score: 0.030
  62. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 Mar 06; 43(4):333-8.
    View in: PubMed
    Score: 0.030
  63. Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet. 2010 Dec; 42(12):1068-76.
    View in: PubMed
    Score: 0.029
  64. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010 Nov; 42(11):937-48.
    View in: PubMed
    Score: 0.029
  65. Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circ Cardiovasc Genet. 2010 Dec; 3(6):523-30.
    View in: PubMed
    Score: 0.029
  66. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010 Oct 14; 467(7317):832-8.
    View in: PubMed
    Score: 0.029
  67. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010 Aug 05; 466(7307):707-13.
    View in: PubMed
    Score: 0.029
  68. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet. 2010 Jun; 3(3):256-66.
    View in: PubMed
    Score: 0.028
  69. Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Circ Cardiovasc Genet. 2010 Jun; 3(3):248-55.
    View in: PubMed
    Score: 0.028
  70. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet. 2009 Nov; 41(11):1191-8.
    View in: PubMed
    Score: 0.027
  71. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA. 2009 Jul 08; 302(2):168-78.
    View in: PubMed
    Score: 0.026
  72. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet. 2009 Jun; 5(6):e1000539.
    View in: PubMed
    Score: 0.026
  73. Genome-wide association study of blood pressure and hypertension. Nat Genet. 2009 Jun; 41(6):677-87.
    View in: PubMed
    Score: 0.026
  74. Genome-wide association meta-analysis for total serum bilirubin levels. Hum Mol Genet. 2009 Jul 15; 18(14):2700-10.
    View in: PubMed
    Score: 0.026
  75. Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ Cardiovasc Genet. 2009 Apr; 2(2):125-33.
    View in: PubMed
    Score: 0.026
  76. Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet. 2009 Apr; 41(4):399-406.
    View in: PubMed
    Score: 0.026
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.