Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Albert Hofman, Ph.D., M.D.

Co-Author

This page shows the publications co-authored by Albert Hofman and Paul Ridker.
Connection Strength

3.671
  1. Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. PLoS One. 2020; 15(11):e0230035.
    View in: PubMed
    Score: 0.058
  2. Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood. Eur J Epidemiol. 2020 Jul; 35(7):685-697.
    View in: PubMed
    Score: 0.056
  3. Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. BMC Cardiovasc Disord. 2019 10 29; 19(1):240.
    View in: PubMed
    Score: 0.054
  4. Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study. JAMA Netw Open. 2019 09 04; 2(9):e1910915.
    View in: PubMed
    Score: 0.054
  5. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Hum Mol Genet. 2019 08 01; 28(15):2615-2633.
    View in: PubMed
    Score: 0.053
  6. Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet. 2018 12; 50(12):1755.
    View in: PubMed
    Score: 0.051
  7. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. Am J Hum Genet. 2018 11 01; 103(5):691-706.
    View in: PubMed
    Score: 0.051
  8. Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet. 2018 10; 50(10):1412-1425.
    View in: PubMed
    Score: 0.050
  9. Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium. Mol Psychiatry. 2019 12; 24(12):1920-1932.
    View in: PubMed
    Score: 0.049
  10. Multi-ethnic genome-wide association study for atrial fibrillation. Nat Genet. 2018 06 11; 50(9):1225-1233.
    View in: PubMed
    Score: 0.049
  11. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Am J Hum Genet. 2018 03 01; 102(3):375-400.
    View in: PubMed
    Score: 0.048
  12. Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts. PLoS One. 2017; 12(12):e0186456.
    View in: PubMed
    Score: 0.048
  13. Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet. 2017 Aug; 13(8):e1006972.
    View in: PubMed
    Score: 0.047
  14. Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet. 2017 07 27; 49(8):1286.
    View in: PubMed
    Score: 0.046
  15. Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney. Hypertension. 2017 Jul 24.
    View in: PubMed
    Score: 0.046
  16. Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep. 2017 05 26; 7:46835.
    View in: PubMed
    Score: 0.046
  17. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep. 2017 04 28; 7:45040.
    View in: PubMed
    Score: 0.046
  18. Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet. 2017 Apr; 13(4):e1006528.
    View in: PubMed
    Score: 0.045
  19. Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet. 2017 Jun; 49(6):946-952.
    View in: PubMed
    Score: 0.045
  20. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. PLoS One. 2017; 12(1):e0167742.
    View in: PubMed
    Score: 0.045
  21. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. Am J Hum Genet. 2017 Jan 05; 100(1):51-63.
    View in: PubMed
    Score: 0.044
  22. SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. J Am Soc Nephrol. 2017 Mar; 28(3):981-994.
    View in: PubMed
    Score: 0.044
  23. PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. Lancet Diabetes Endocrinol. 2017 02; 5(2):97-105.
    View in: PubMed
    Score: 0.044
  24. KLB is associated with alcohol drinking, and its gene product ß-Klotho is necessary for FGF21 regulation of alcohol preference. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):14372-14377.
    View in: PubMed
    Score: 0.044
  25. A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nat Commun. 2016 11 23; 7:13357.
    View in: PubMed
    Score: 0.044
  26. Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nat Genet. 2016 12; 48(12):1462-1472.
    View in: PubMed
    Score: 0.044
  27. Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nat Genet. 2016 09 28; 48(10):1296.
    View in: PubMed
    Score: 0.044
  28. The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet. 2016 10; 48(10):1171-1184.
    View in: PubMed
    Score: 0.044
  29. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. J Med Genet. 2016 12; 53(12):835-845.
    View in: PubMed
    Score: 0.043
  30. Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2016 06; 12(6):e1006166.
    View in: PubMed
    Score: 0.043
  31. Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nat Genet. 2016 08; 48(8):856-66.
    View in: PubMed
    Score: 0.043
  32. Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies. Gastroenterology. 2016 Aug; 151(2):351-363.e28.
    View in: PubMed
    Score: 0.042
  33. Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. PLoS One. 2016; 11(3):e0144997.
    View in: PubMed
    Score: 0.042
  34. Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nat Commun. 2016 Feb 01; 7:10494.
    View in: PubMed
    Score: 0.042
  35. Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function. Nat Commun. 2016 Jan 21; 7:10023.
    View in: PubMed
    Score: 0.042
  36. Corrigendum: Rare coding variants and X-linked loci associated with age at menarche. Nat Commun. 2015 Dec 17; 6:10257.
    View in: PubMed
    Score: 0.041
  37. A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. Hum Mol Genet. 2016 Jan 15; 25(2):358-70.
    View in: PubMed
    Score: 0.041
  38. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2015 Oct; 11(10):e1005378.
    View in: PubMed
    Score: 0.041
  39. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nat Genet. 2015 Nov; 47(11):1294-1303.
    View in: PubMed
    Score: 0.041
  40. Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture. Nature. 2015 Oct 01; 526(7571):112-7.
    View in: PubMed
    Score: 0.041
  41. A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. Nat Genet. 2015 Oct; 47(10):1121-1130.
    View in: PubMed
    Score: 0.041
  42. Rare coding variants and X-linked loci associated with age at menarche. Nat Commun. 2015 Aug 04; 6:7756.
    View in: PubMed
    Score: 0.040
  43. Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF. Blood. 2015 Sep 10; 126(11):e19-29.
    View in: PubMed
    Score: 0.040
  44. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015 Feb 12; 518(7538):187-196.
    View in: PubMed
    Score: 0.039
  45. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015 Feb 12; 518(7538):197-206.
    View in: PubMed
    Score: 0.039
  46. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nat Commun. 2015 Jan 29; 6:5897.
    View in: PubMed
    Score: 0.039
  47. No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. PLoS One. 2014; 9(12):e111156.
    View in: PubMed
    Score: 0.039
  48. Genome-wide association study of kidney function decline in individuals of European descent. Kidney Int. 2015 May; 87(5):1017-29.
    View in: PubMed
    Score: 0.039
  49. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77(8):749-63.
    View in: PubMed
    Score: 0.038
  50. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun. 2014 Oct 28; 5:5068.
    View in: PubMed
    Score: 0.038
  51. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Mol Psychiatry. 2015 May; 20(5):647-656.
    View in: PubMed
    Score: 0.038
  52. Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet. 2014 Nov; 46(11):1173-86.
    View in: PubMed
    Score: 0.038
  53. FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Hum Mol Genet. 2014 Dec 20; 23(25):6961-72.
    View in: PubMed
    Score: 0.038
  54. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 2014 Oct 02; 514(7520):92-97.
    View in: PubMed
    Score: 0.038
  55. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet. 2014 Jul 03; 95(1):49-65.
    View in: PubMed
    Score: 0.037
  56. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. Am J Hum Genet. 2014 Jul 03; 95(1):24-38.
    View in: PubMed
    Score: 0.037
  57. Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. 2014 Aug; 112(4):317-38.
    View in: PubMed
    Score: 0.037
  58. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet. 2013 Nov; 45(11):1345-52.
    View in: PubMed
    Score: 0.036
  59. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013 Nov; 45(11):1274-1283.
    View in: PubMed
    Score: 0.036
  60. Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol. 2013 Dec; 24(12):2105-17.
    View in: PubMed
    Score: 0.035
  61. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 2013 Sep 17; 128(12):1310-24.
    View in: PubMed
    Score: 0.035
  62. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr. 2013 Sep; 98(3):668-76.
    View in: PubMed
    Score: 0.035
  63. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nat Genet. 2013 Aug; 45(8):912-917.
    View in: PubMed
    Score: 0.035
  64. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet. 2013 Jun; 9(6):e1003500.
    View in: PubMed
    Score: 0.035
  65. A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Genet Epidemiol. 2013 Jul; 37(5):512-521.
    View in: PubMed
    Score: 0.035
  66. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 2013 May; 45(5):501-12.
    View in: PubMed
    Score: 0.034
  67. Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. Am J Epidemiol. 2013 Aug 01; 178(3):451-60.
    View in: PubMed
    Score: 0.034
  68. A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet. 2013 Apr 01; 22(7):1465-72.
    View in: PubMed
    Score: 0.034
  69. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet. 2013 Feb; 45(2):145-54.
    View in: PubMed
    Score: 0.034
  70. C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med. 2012 Oct 04; 367(14):1310-20.
    View in: PubMed
    Score: 0.033
  71. FTO genotype is associated with phenotypic variability of body mass index. Nature. 2012 Oct 11; 490(7419):267-72.
    View in: PubMed
    Score: 0.033
  72. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet. 2012 Dec 15; 21(24):5329-43.
    View in: PubMed
    Score: 0.033
  73. Lipid-related markers and cardiovascular disease prediction. JAMA. 2012 Jun 20; 307(23):2499-506.
    View in: PubMed
    Score: 0.033
  74. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet. 2012 Apr 29; 44(6):670-5.
    View in: PubMed
    Score: 0.032
  75. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet. 2012 Apr 15; 44(5):491-501.
    View in: PubMed
    Score: 0.032
  76. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet. 2012; 8(3):e1002584.
    View in: PubMed
    Score: 0.032
  77. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012; 8(3):e1002607.
    View in: PubMed
    Score: 0.032
  78. Reproductive aging-associated common genetic variants and the risk of breast cancer. Breast Cancer Res. 2012 Mar 20; 14(2):R54.
    View in: PubMed
    Score: 0.032
  79. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet. 2012 Mar 31; 379(9822):1205-13.
    View in: PubMed
    Score: 0.032
  80. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet. 2012 Jan 22; 44(3):260-8.
    View in: PubMed
    Score: 0.032
  81. Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med. 2011 Nov; 8(11):e1001116.
    View in: PubMed
    Score: 0.031
  82. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet. 2011 Sep 11; 43(10):1005-11.
    View in: PubMed
    Score: 0.031
  83. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 Sep 11; 478(7367):103-9.
    View in: PubMed
    Score: 0.031
  84. Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet. 2011 Jun 01; 20(11):2273-84.
    View in: PubMed
    Score: 0.030
  85. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation. 2011 Feb 22; 123(7):731-8.
    View in: PubMed
    Score: 0.030
  86. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet. 2010 Dec; 42(12):1077-85.
    View in: PubMed
    Score: 0.029
  87. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet. 2010 Nov; 42(11):949-60.
    View in: PubMed
    Score: 0.029
  88. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010 Nov; 42(11):937-48.
    View in: PubMed
    Score: 0.029
  89. Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors. Circ Cardiovasc Genet. 2010 Dec; 3(6):523-30.
    View in: PubMed
    Score: 0.029
  90. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010 Oct 14; 467(7317):832-8.
    View in: PubMed
    Score: 0.029
  91. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010 Aug 05; 466(7307):707-13.
    View in: PubMed
    Score: 0.029
  92. New loci associated with kidney function and chronic kidney disease. Nat Genet. 2010 May; 42(5):376-84.
    View in: PubMed
    Score: 0.028
  93. Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet. 2009 Jun; 41(6):712-7.
    View in: PubMed
    Score: 0.026
  94. Collaborative meta-analysis of individual participant data from observational studies of Lp-PLA2 and cardiovascular diseases. Eur J Cardiovasc Prev Rehabil. 2007 Feb; 14(1):3-11.
    View in: PubMed
    Score: 0.022
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.