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profileAlbert Hofman, Ph.D., M.D.

TitleStephen B. Kay Family Professor of Public Health and Clinical Epidemiology
InstitutionHarvard T.H. Chan School of Public Health
DepartmentEpidemiology
AddressHarvard School of Public Health
Kresge Bldg, 9th Flr, Room 905 Epidemiology
677 Huntington Ave
Boston MA 02115
Phone617/432-3942
vCardDownload vCard (login for email)
Other Positions
TitleChair, Dept of Epidemiology
InstitutionHarvard T.H. Chan School of Public Health
DepartmentEpidemiology


Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ham AC, Aarts N, Noordam R, Rivadeneira F, Ziere G, Zillikens MC, Tiemeier H, van der Velde N, Hofman A, Uitterlinden AG, Visser LE, Stricker BH. Use of Selective Serotonin Reuptake Inhibitors and Bone Mineral Density Change: A Population-Based Longitudinal Study in Middle-Aged and Elderly Individuals. J Clin Psychopharmacol. 2017 Oct; 37(5):524-530. PMID: 28816927.
    View in: PubMed
  2. Hollander WD, Boer CG, Hart DJ, Yau MS, Ramos YFM, Metrustry S, Broer L, Deelen J, Cupples LA, Rivadeneira F, Kloppenburg M, Peters M, Spector TD, Hofman A, Slagboom PE, Nelissen RGHH, Uitterlinden AG, Felson DT, Valdes AM, Meulenbelt I, van Meurs JJB. Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand. Ann Rheum Dis. 2017 Aug 30. PMID: 28855172.
    View in: PubMed
  3. Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D, Xue L, Workalemahu T, Heard-Costa NL, den Hoed M, Ahluwalia TS, Qi Q, Ngwa JS, Renström F, Quaye L, Eicher JD, Hayes JE, Cornelis M, Kutalik Z, Lim E, Luan J, Huffman JE, Zhang W, Zhao W, Griffin PJ, Haller T, Ahmad S, Marques-Vidal PM, Bien S, Yengo L, Teumer A, Smith AV, Kumari M, Harder MN, Justesen JM, Kleber ME, Hollensted M, Lohman K, Rivera NV, Whitfield JB, Zhao JH, Stringham HM, Lyytikäinen LP, Huppertz C, Willemsen G, Peyrot WJ, Wu Y, Kristiansson K, Demirkan A, Fornage M, Hassinen M, Bielak LF, Cadby G, Tanaka T, Mägi R, van der Most PJ, Jackson AU, Bragg-Gresham JL, Vitart V, Marten J, Navarro P, Bellis C, Pasko D, Johansson Å, Snitker S, Cheng YC, Eriksson J, Lim U, Aadahl M, Adair LS, Amin N, Balkau B, Auvinen J, Beilby J, Bergman RN, Bergmann S, Bertoni AG, Blangero J, Bonnefond A, Bonnycastle LL, Borja JB, Brage S, Busonero F, Buyske S, Campbell H, Chines PS, Collins FS, Corre T, Smith GD, Delgado GE, Dueker N, Dörr M, Ebeling T, Eiriksdottir G, Esko T, Faul JD, Fu M, Færch K, Gieger C, Gläser S, Gong J, Gordon-Larsen P, Grallert H, Grammer TB, Grarup N, van Grootheest G, Harald K, Hastie ND, Havulinna AS, Hernandez D, Hindorff L, Hocking LJ, Holmens OL, Holzapfel C, Hottenga JJ, Huang J, Huang T, Hui J, Huth C, Hutri-Kähönen N, James AL, Jansson JO, Jhun MA, Juonala M, Kinnunen L, Koistinen HA, Kolcic I, Komulainen P, Kuusisto J, Kvaløy K, Kähönen M, Lakka TA, Launer LJ, Lehne B, Lindgren CM, Lorentzon M, Luben R, Marre M, Milaneschi Y, Monda KL, Montgomery GW, De Moor MHM, Mulas A, Müller-Nurasyid M, Musk AW, Männikkö R, Männistö S, Narisu N, Nauck M, Nettleton JA, Nolte IM, Oldehinkel AJ, Olden M, Ong KK, Padmanabhan S, Paternoster L, Perez J, Perola M, Peters A, Peters U, Peyser PA, Prokopenko I, Puolijoki H, Raitakari OT, Rankinen T, Rasmussen-Torvik LJ, Rawal R, Ridker PM, Rose LM, Rudan I, Sarti C, Sarzynski MA, Savonen K, Scott WR, Sanna S, Shuldiner AR, Sidney S, Silbernagel G, Smith BH, Smith JA, Snieder H, Stancáková A, Sternfeld B, Swift AJ, Tammelin T, Tan ST, Thorand B, Thuillier D, Vandenput L, Vestergaard H, van Vliet-Ostaptchouk JV, Vohl MC, Völker U, Waeber G, Walker M, Wild S, Wong A, Wright AF, Zillikens MC, Zubair N, Haiman CA, Lemarchand L, Gyllensten U, Ohlsson C, Hofman A, Rivadeneira F, Uitterlinden AG, Pérusse L, Wilson JF, Hayward C, Polasek O, Cucca F, Hveem K, Hartman CA, Tönjes A, Bandinelli S, Palmer LJ, Kardia SLR, Rauramaa R, Sørensen TIA, Tuomilehto J, Salomaa V, Penninx BWJH, de Geus EJC, Boomsma DI, Lehtimäki T, Mangino M, Laakso M, Bouchard C, Martin NG, Kuh D, Liu Y, Linneberg A, März W, Strauch K, Kivimäki M, Harris TB, Gudnason V, Völzke H, Qi L, Järvelin MR, Chambers JC, Kooner JS, Froguel P, Kooperberg C, Vollenweider P, Hallmans G, Hansen T, Pedersen O, Metspalu A, Wareham NJ, Langenberg C, Weir DR, Porteous DJ, Boerwinkle E, Chasman DI, Abecasis GR, Barroso I, McCarthy MI, Frayling TM, O'Connell JR, van Duijn CM, Boehnke M, Heid IM, Mohlke KL, Strachan DP, Fox CS, Liu CT, Hirschhorn JN, Klein RJ, Johnson AD, Borecki IB, Franks PW, North KE, Cupples LA, Loos RJF, Kilpeläinen TO. Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet. 2017 Aug; 13(8):e1006972. PMID: 28832619.
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  4. Chaker L, Korevaar TIM, Rizopoulos D, Collet TH, Völzke H, Hofman A, Rodondi N, Cappola AR, Peeters RP, Franco OH. Defining Optimal Health Range for Thyroid Function Based on the Risk of Cardiovascular Disease. J Clin Endocrinol Metab. 2017 Aug 01; 102(8):2853-2861. PMID: 28520952.
    View in: PubMed
  5. Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, Low SK, Weeke PE, Müller-Nurasyid M, Smith JG, Brody JA, Niemeijer MN, Dörr M, Trompet S, Huffman J, Gustafsson S, Schurmann C, Kleber ME, Lyytikäinen LP, Seppälä I, Malik R, R V R Horimoto A, Perez M, Sinisalo J, Aeschbacher S, Thériault S, Yao J, Radmanesh F, Weiss S, Teumer A, Choi SH, Weng LC, Clauss S, Deo R, Rader DJ, Shah SH, Sun A, Hopewell JC, Debette S, Chauhan G, Yang Q, Worrall BB, Paré G, Kamatani Y, Hagemeijer YP, Verweij N, Siland JE, Kubo M, Smith JD, Van Wagoner DR, Bis JC, Perz S, Psaty BM, Ridker PM, Magnani JW, Harris TB, Launer LJ, Shoemaker MB, Padmanabhan S, Haessler J, Bartz TM, Waldenberger M, Lichtner P, Arendt M, Krieger JE, Kähönen M, Risch L, Mansur AJ, Peters A, Smith BH, Lind L, Scott SA, Lu Y, Bottinger EB, Hernesniemi J, Lindgren CM, Wong JA, Huang J, Eskola M, Morris AP, Ford I, Reiner AP, Delgado G, Chen LY, Chen YI, Sandhu RK, Li M, Boerwinkle E, Eisele L, Lannfelt L, Rost N, Anderson CD, Taylor KD, Campbell A, Magnusson PK, Porteous D, Hocking LJ, Vlachopoulou E, Pedersen NL, Nikus K, Orho-Melander M, Hamsten A, Heeringa J, Denny JC, Kriebel J, Darbar D, Newton-Cheh C, Shaffer C, Macfarlane PW, Heilmann-Heimbach S, Almgren P, Huang PL, Sotoodehnia N, Soliman EZ, Uitterlinden AG, Hofman A, Franco OH, Völker U, Jöckel KH, Sinner MF, Lin HJ, Guo X, Dichgans M, Ingelsson E, Kooperberg C, Melander O, J F Loos R, Laurikka J, Conen D, Rosand J, van der Harst P, Lokki ML, Kathiresan S, Pereira A, Jukema JW, Hayward C, Rotter JI, März W, Lehtimäki T, Stricker BH, Chung MK, Felix SB, Gudnason V, Alonso A, Roden DM, Kääb S, Chasman DI, Heckbert SR, Benjamin EJ, Tanaka T, Lunetta KL, Lubitz SA, Ellinor PT. Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet. 2017 Jul 27; 49(8):1286. PMID: 28747752.
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  6. Yano Y, O'Donnell CJ, Kuller L, Kavousi M, Erbel R, Ning H, D'Agostino R, Newman AB, Nasir K, Hofman A, Lehmann N, Dhana K, Blankstein R, Hoffmann U, Möhlenkamp S, Massaro JM, Mahabadi AA, Lima JAC, Ikram MA, Jöckel KH, Franco OH, Liu K, Lloyd-Jones D, Greenland P. Association of Coronary Artery Calcium Score vs Age With Cardiovascular Risk in Older Adults: An Analysis of Pooled Population-Based Studies. JAMA Cardiol. 2017 Jul 26. PMID: 28746709.
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  7. Hendriks M, Verhoeven VJM, Buitendijk GHS, Polling JR, Meester-Smoor MA, Hofman A, Kamermans M, Ingeborgh van den Born L, Klaver CCW. Development of refractive errors - what can we learn from inherited retinal dystrophies? Am J Ophthalmol. 2017 Jul 24. PMID: 28751151.
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  8. Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, Åkesson K, Amin N, Baier LJ, Barroso I, Bennett DA, Bertram L, Biffar R, Bochud M, Boehnke M, Borecki IB, Buchman AS, Byberg L, Campbell H, Campos Obanda N, Cauley JA, Cawthon PM, Cederberg H, Chen Z, Cho NH, Jin Choi H, Claussnitzer M, Collins F, Cummings SR, De Jager PL, Demuth I, Dhonukshe-Rutten RAM, Diatchenko L, Eiriksdottir G, Enneman AW, Erdos M, Eriksson JG, Eriksson J, Estrada K, Evans DS, Feitosa MF, Fu M, Garcia M, Gieger C, Girke T, Glazer NL, Grallert H, Grewal J, Han BG, Hanson RL, Hayward C, Hofman A, Hoffman EP, Homuth G, Hsueh WC, Hubal MJ, Hubbard A, Huffman KM, Husted LB, Illig T, Ingelsson E, Ittermann T, Jansson JO, Jordan JM, Jula A, Karlsson M, Khaw KT, Kilpeläinen TO, Klopp N, Kloth JSL, Koistinen HA, Kraus WE, Kritchevsky S, Kuulasmaa T, Kuusisto J, Laakso M, Lahti J, Lang T, Langdahl BL, Launer LJ, Lee JY, Lerch MM, Lewis JR, Lind L, Lindgren C, Liu Y, Liu T, Liu Y, Ljunggren Ö, Lorentzon M, Luben RN, Maixner W, McGuigan FE, Medina-Gomez C, Meitinger T, Melhus H, Mellström D, Melov S, Michaëlsson K, Mitchell BD, Morris AP, Mosekilde L, Newman A, Nielson CM, O'Connell JR, Oostra BA, Orwoll ES, Palotie A, Parker S, Peacock M, Perola M, Peters A, Polasek O, Prince RL, Räikkönen K, Ralston SH, Ripatti S, Robbins JA, Rotter JI, Rudan I, Salomaa V, Satterfield S, Schadt EE, Schipf S, Scott L, Sehmi J, Shen J, Soo Shin C, Sigurdsson G, Smith S, Soranzo N, Stancáková A, Steinhagen-Thiessen E, Streeten EA, Styrkarsdottir U, Swart KMA, Tan ST, Tarnopolsky MA, Thompson P, Thomson CA, Thorsteinsdottir U, Tikkanen E, Tranah GJ, Tuomilehto J, van Schoor NM, Verma A, Vollenweider P, Völzke H, Wactawski-Wende J, Walker M, Weedon MN, Welch R, Wichmann HE, Widen E, Williams FMK, Wilson JF, Wright NC, Xie W, Yu L, Zhou Y, Chambers JC, Döring A, van Duijn CM, Econs MJ, Gudnason V, Kooner JS, Psaty BM, Spector TD, Stefansson K, Rivadeneira F, Uitterlinden AG, Wareham NJ, Ossowski V, Waterworth D, Loos RJF, Karasik D, Harris TB, Ohlsson C, Kiel DP. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nat Commun. 2017 Jul 19; 8(1):80. PMID: 28724990.
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  9. Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Jr WTL, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-Stählbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, Lipton RB, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nat Genet. 2017 Sep; 49(9):1373-1384. PMID: 28714976.
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  10. Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SLR, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G. Correction: The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017 Jul 07. PMID: 28696945.
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  11. Collares FM, Korevaar TIM, Hofman A, Steegers EAP, Peeters RP, Jaddoe VWV, Gaillard R. Maternal thyroid function, prepregnancy obesity and gestational weight gain-The Generation R Study: A prospective cohort study. Clin Endocrinol (Oxf). 2017 Jun 30. PMID: 28666083.
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  12. van der Knaap NJF, Klumpers F, El Marroun H, Mous S, Schubert D, Jaddoe V, Hofman A, Homberg JR, Tiemeier H, White T, Fernández G. Maternal depressive symptoms during pregnancy are associated with amygdala hyperresponsivity in children. Eur Child Adolesc Psychiatry. 2017 Jun 30. PMID: 28667426.
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  13. Nano J, Ghanbari M, Wang W, de Vries PS, Dhana K, Muka T, Uitterlinden AG, van Meurs JBJ, Hofman A, Franco OH, Pan Q, Darwish Murad S, Dehghan A. Epigenome-wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis. Gastroenterology. 2017 Jun 15. PMID: 28624579.
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  14. Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer MA, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC. Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun. 2017 Jun 14; 8:15805. PMID: 28613276.
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  15. Tideman JWL, Polling JR, Hofman A, Jaddoe VW, Mackenbach JP, Klaver CC. Environmental factors explain socioeconomic prevalence differences in myopia in 6-year-old children. Br J Ophthalmol. 2017 Jun 12. PMID: 28607175.
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  16. Springelkamp H, Wolfs RC, Ramdas WD, Hofman A, Vingerling JR, Klaver CC, Jansonius NM. Incidence of glaucomatous visual field loss after two decades of follow-up: the Rotterdam Study. Eur J Epidemiol. 2017 Jun 12. PMID: 28608186.
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  17. Toemen L, Gaillard R, van Osch-Gevers L, Helbing WA, Hofman A, Jaddoe VW. Tracking of structural and functional cardiac measures from infancy into school-age. Eur J Prev Cardiol. 2017 Sep; 24(13):1408-1415. PMID: 28604079.
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  18. Ham AC, van Dijk SC, Swart KMA, Enneman AW, van der Zwaluw NL, Brouwer-Brolsma EM, van Schoor NM, Zillikens MC, Lips P, de Groot LCPGM, Hofman A, Witkamp RF, Uitterlinden AG, Stricker BH, van der Velde N. Beta-blocker use and fall risk in older individuals: Original results from two studies with meta-analysis. Br J Clin Pharmacol. 2017 Jun 07. PMID: 28589543.
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  19. Wolters FJ, Zonneveld HI, Hofman A, van der Lugt A, Koudstaal PJ, Vernooij MW, Ikram MA. Cerebral Perfusion and the Risk of Dementia: A Population-Based Study. Circulation. 2017 Aug 22; 136(8):719-728. PMID: 28588075.
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  20. Hanewinckel R, Ikram MA, Franco OH, Hofman A, Drenthen J, van Doorn PA. High body mass and kidney dysfunction relate to worse nerve function, even in adults without neuropathy. J Peripher Nerv Syst. 2017 Jun; 22(2):112-120. PMID: 28429469.
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  21. Hanewinckel R, Drenthen J, Verlinden VJA, Darweesh SKL, van der Geest JN, Hofman A, van Doorn PA, Ikram MA. Polyneuropathy relates to impairment in daily activities, worse gait, and fall-related injuries. Neurology. 2017 Jul 04; 89(1):76-83. PMID: 28566544.
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  22. Gorski M, Most PJV, Teumer A, Chu AY, Li M, Mijatovic V, Nolte IM, Cocca M, Taliun D, Gomez F, Li Y, Tayo B, Tin A, Feitosa MF, Aspelund T, Attia J, Biffar R, Bochud M, Boerwinkle E, Borecki I, Bottinger EP, Chen MH, Chouraki V, Ciullo M, Coresh J, Cornelis MC, Curhan GC, Adamo AP, Dehghan A, Dengler L, Ding J, Eiriksdottir G, Endlich K, Enroth S, Esko T, Franco OH, Gasparini P, Gieger C, Girotto G, Gottesman O, Gudnason V, Gyllensten U, Hancock SJ, Harris TB, Helmer C, Höllerer S, Hofer E, Hofman A, Holliday EG, Homuth G, Hu FB, Huth C, Hutri-Kähönen N, Hwang SJ, Imboden M, Johansson Å, Kähönen M, König W, Kramer H, Krämer BK, Kumar A, Kutalik Z, Lambert JC, Launer LJ, Lehtimäki T, de Borst MH, Navis G, Swertz M, Liu Y, Lohman K, Loos RJF, Lu Y, Lyytikäinen LP, McEvoy MA, Meisinger C, Meitinger T, Metspalu A, Metzger M, Mihailov E, Mitchell P, Nauck M, Oldehinkel AJ, Olden M, Wjh Penninx B, Pistis G, Pramstaller PP, Probst-Hensch N, Raitakari OT, Rettig R, Ridker PM, Rivadeneira F, Robino A, Rosas SE, Ruderfer D, Ruggiero D, Saba Y, Sala C, Schmidt H, Schmidt R, Scott RJ, Sedaghat S, Smith AV, Sorice R, Stengel B, Stracke S, Strauch K, Toniolo D, Uitterlinden AG, Ulivi S, Viikari JS, Völker U, Vollenweider P, Völzke H, Vuckovic D, Waldenberger M, Wang JJ, Yang Q, Chasman DI, Tromp G, Snieder H, Heid IM, Fox CS, Köttgen A, Pattaro C, Böger CA, Fuchsberger C. Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep. 2017 05 26; 7:46835. PMID: 28548086.
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  23. Tachmazidou I, Süveges D, Min JL, Ritchie GRS, Steinberg J, Walter K, Iotchkova V, Schwartzentruber J, Huang J, Memari Y, McCarthy S, Crawford AA, Bombieri C, Cocca M, Farmaki AE, Gaunt TR, Jousilahti P, Kooijman MN, Lehne B, Malerba G, Männistö S, Matchan A, Medina-Gomez C, Metrustry SJ, Nag A, Ntalla I, Paternoster L, Rayner NW, Sala C, Scott WR, Shihab HA, Southam L, St Pourcain B, Traglia M, Trajanoska K, Zaza G, Zhang W, Artigas MS, Bansal N, Benn M, Chen Z, Danecek P, Lin WY, Locke A, Luan J, Manning AK, Mulas A, Sidore C, Tybjaerg-Hansen A, Varbo A, Zoledziewska M, Finan C, Hatzikotoulas K, Hendricks AE, Kemp JP, Moayyeri A, Panoutsopoulou K, Szpak M, Wilson SG, Boehnke M, Cucca F, Di Angelantonio E, Langenberg C, Lindgren C, McCarthy MI, Morris AP, Nordestgaard BG, Scott RA, Tobin MD, Wareham NJ, Burton P, Chambers JC, Smith GD, Dedoussis G, Felix JF, Franco OH, Gambaro G, Gasparini P, Hammond CJ, Hofman A, Jaddoe VWV, Kleber M, Kooner JS, Perola M, Relton C, Ring SM, Rivadeneira F, Salomaa V, Spector TD, Stegle O, Toniolo D, Uitterlinden AG, Barroso I, Greenwood CMT, Perry JRB, Walker BR, Butterworth AS, Xue Y, Durbin R, Small KS, Soranzo N, Timpson NJ, Zeggini E. Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. Am J Hum Genet. 2017 Jun 01; 100(6):865-884. PMID: 28552196.
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  24. Holstege H, van der Lee SJ, Hulsman M, Wong TH, van Rooij JG, Weiss M, Louwersheimer E, Wolters FJ, Amin N, Uitterlinden AG, Hofman A, Ikram MA, van Swieten JC, Meijers-Heijboer H, van der Flier WM, Reinders MJ, van Duijn CM, Scheltens P. Characterization of pathogenic SORL1 genetic variants for association with Alzheimer's disease: a clinical interpretation strategy. Eur J Hum Genet. 2017 Aug; 25(8):973-981. PMID: 28537274.
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  25. Saavedra Pérez HC, Direk N, Milic J, Ikram MA, Hofman A, Tiemeier H. The Impact of Complicated Grief on Diurnal Cortisol Levels Two Years After Loss: A Population-Based Study. Psychosom Med. 2017 May; 79(4):426-433. PMID: 27879552.
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  26. Gorski M, van der Most PJ, Teumer A, Chu AY, Li M, Mijatovic V, Nolte IM, Cocca M, Taliun D, Gomez F, Li Y, Tayo B, Tin A, Feitosa MF, Aspelund T, Attia J, Biffar R, Bochud M, Boerwinkle E, Borecki I, Bottinger EP, Chen MH, Chouraki V, Ciullo M, Coresh J, Cornelis MC, Curhan GC, d'Adamo AP, Dehghan A, Dengler L, Ding J, Eiriksdottir G, Endlich K, Enroth S, Esko T, Franco OH, Gasparini P, Gieger C, Girotto G, Gottesman O, Gudnason V, Gyllensten U, Hancock SJ, Harris TB, Helmer C, Höllerer S, Hofer E, Hofman A, Holliday EG, Homuth G, Hu FB, Huth C, Hutri-Kähönen N, Hwang SJ, Imboden M, Johansson Å, Kähönen M, König W, Kramer H, Krämer BK, Kumar A, Kutalik Z, Lambert JC, Launer LJ, Lehtimäki T, de Borst M, Navis G, Swertz M, Liu Y, Lohman K, Loos RJF, Lu Y, Lyytikäinen LP, McEvoy MA, Meisinger C, Meitinger T, Metspalu A, Metzger M, Mihailov E, Mitchell P, Nauck M, Oldehinkel AJ, Olden M, Wjh Penninx B, Pistis G, Pramstaller PP, Probst-Hensch N, Raitakari OT, Rettig R, Ridker PM, Rivadeneira F, Robino A, Rosas SE, Ruderfer D, Ruggiero D, Saba Y, Sala C, Schmidt H, Schmidt R, Scott RJ, Sedaghat S, Smith AV, Sorice R, Stengel B, Stracke S, Strauch K, Toniolo D, Uitterlinden AG, Ulivi S, Viikari JS, Völker U, Vollenweider P, Völzke H, Vuckovic D, Waldenberger M, Jin Wang J, Yang Q, Chasman DI, Tromp G, Snieder H, Heid IM, Fox CS, Köttgen A, Pattaro C, Böger CA, Fuchsberger C. 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function. Sci Rep. 2017 04 28; 7:45040. PMID: 28452372.
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  29. Pletsch-Borba L, Selwaness M, van der Lugt A, Hofman A, Franco OH, Vernooij MW. Change in Carotid Plaque Components: A 4-Year Follow-Up Study With Serial MR Imaging. JACC Cardiovasc Imaging. 2017 Apr 12. PMID: 28412421.
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  31. Melo van Lent D, Leermakers ET, Hofman A, Stricker BH, Brusselle GG, Franco OH, Lahousse L, Kiefte-de Jong JC. Association between lutein intake and lung function in adults: the Rotterdam Study. Br J Nutr. 2017 Mar; 117(5):720-730. PMID: 28376947.
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  32. van 't Hof FN, Vaucher J, Holmes MV, de Wilde A, Baas AF, Blankensteijn JD, Hofman A, Kiemeney LA, Rivadeneira F, Uitterlinden AG, Vermeulen SH, Rinkel GJ, de Bakker PI, Ruigrok YM. Genetic variants associated with type 2 diabetes and adiposity and risk of intracranial and abdominal aortic aneurysms. Eur J Hum Genet. 2017 Jun; 25(6):758-762. PMID: 28378816.
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  33. Stringa N, Brahimaj A, Zaciragic A, Dehghan A, Ikram MA, Hofman A, Muka T, Kiefte-de Jong JC, Franco OH. Relation of antioxidant capacity of diet and markers of oxidative status with C-reactive protein and adipocytokines: a prospective study. Metabolism. 2017 Jun; 71:171-181. PMID: 28521871.
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  34. Böger CA, Gorski M, McMahon GM, Xu H, Chang YC, van der Most PJ, Navis G, Nolte IM, de Borst MH, Zhang W, Lehne B, Loh M, Tan ST, Boerwinkle E, Grams ME, Sekula P, Li M, Wilmot B, Moon JG, Scheet P, Cucca F, Xiao X, Lyytikäinen LP, Delgado G, Grammer TB, Kleber ME, Sedaghat S, Rivadeneira F, Corre T, Kutalik Z, Bergmann S, Nielson CM, Srikanth P, Teumer A, Müller-Nurasyid M, Brockhaus AC, Pfeufer A, Rathmann W, Peters A, Matsumoto M, de Andrade M, Atkinson EJ, Robinson-Cohen C, de Boer IH, Hwang SJ, Heid IM, Gögele M, Concas MP, Tanaka T, Bandinelli S, Nalls MA, Singleton A, Tajuddin SM, Adeyemo A, Zhou J, Doumatey A, McWeeney S, Murabito J, Franceschini N, Flessner M, Shlipak M, Wilson JG, Chen G, Rotimi CN, Zonderman AB, Evans MK, Ferrucci L, Devuyst O, Pirastu M, Shuldiner A, Hicks AA, Pramstaller PP, Kestenbaum B, Kardia SLR, Turner ST, Study LC, Briske TE, Gieger C, Strauch K, Meisinger C, Meitinger T, Völker U, Nauck M, Völzke H, Vollenweider P, Bochud M, Waeber G, Kähönen M, Lehtimäki T, März W, Dehghan A, Franco OH, Uitterlinden AG, Hofman A, Taylor HA, Chambers JC, Kooner JS, Fox CS, Hitzemann R, Orwoll ES, Pattaro C, Schlessinger D, Köttgen A, Snieder H, Parsa A, Cohen DM. NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. J Am Soc Nephrol. 2017 Aug; 28(8):2311-2321. PMID: 28360221.
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  35. Wolters FJ, van der Lee SJ, Koudstaal PJ, van Duijn CM, Hofman A, Ikram MK, Vernooij MW, Ikram MA. Parental family history of dementia in relation to subclinical brain disease and dementia risk. Neurology. 2017 Apr 25; 88(17):1642-1649. PMID: 28356461.
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  36. Campos-Obando N, Koek WNH, Hooker ER, van der Eerden BC, Pols HA, Hofman A, van Leeuwen JP, Uitterlinden AG, Nielson CM, Zillikens MC. Serum Phosphate Is Associated With Fracture Risk: The Rotterdam Study and MrOS. J Bone Miner Res. 2017 Jun; 32(6):1182-1193. PMID: 28177140.
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  37. Verlinden VJA, de Kruijf M, Bierma-Zeinstra SMA, Hofman A, Uitterlinden AG, Ikram MA, van Meurs JBJ, van der Geest JN. Asymptomatic radiographic hip osteoarthritis is associated with gait differences, especially in women: A population-based study. Gait Posture. 2017 May; 54:248-254. PMID: 28359929.
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  38. Nano J, Muka T, Ligthart S, Hofman A, Darwish Murad S, Janssen H, Franco OH, Dehghan A. Gamma-glutamyltransferase levels, prediabetes and type 2 diabetes: a Mendelian Randomization study. Int J Epidemiol. 2017 Mar 13. PMID: 28338987.
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  39. Brahimaj A, Ligthart S, Ghanbari M, Ikram MA, Hofman A, Franco OH, Kavousi M, Dehghan A. Novel inflammatory markers for incident pre-diabetes and type 2 diabetes: the Rotterdam Study. Eur J Epidemiol. 2017 Mar; 32(3):217-226. PMID: 28258520.
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  40. Mahmoudpour SH, Veluchamy A, Siddiqui MK, Asselbergs FW, Souverein PC, de Keyser CE, Hofman A, Lang CC, Doney AS, Stricker BH, de Boer A, Maitland-van der Zee AH, Palmer CN. Meta-analysis of genome-wide association studies on the intolerance of angiotensin-converting enzyme inhibitors. Pharmacogenet Genomics. 2017 Mar; 27(3):112-119. PMID: 28030426.
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  41. Marinkovic T, Toemen L, Kruithof CJ, Reiss I, van Osch-Gevers L, Hofman A, Franco OH, Jaddoe VWV. Early Infant Growth Velocity Patterns and Cardiovascular and Metabolic Outcomes in Childhood. J Pediatr. 2017 Jul; 186:57-63.e4. PMID: 28256212.
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  42. Tromp I, Kiefte-de Jong J, Raat H, Jaddoe V, Franco O, Hofman A, de Jongste J, Moll H. Breastfeeding and the risk of respiratory tract infections after infancy: The Generation R Study. PLoS One. 2017; 12(2):e0172763. PMID: 28231310.
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  43. Dhana K, Koolhaas CM, Schoufour JD, Rivadeneira F, Hofman A, Kavousi M, Franco OH. Erratum to "Association of anthropometric measures with fat and fat-free mass in the elderly: The Rotterdam study" [Maturitas 88 (2016) 96-100]. Maturitas. 2017 Jun; 100:92. PMID: 28236487.
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  44. Kieboom BC, Ligthart S, Dehghan A, Kurstjens S, de Baaij JH, Franco OH, Hofman A, Zietse R, Stricker BH, Hoorn EJ. Serum magnesium and the risk of prediabetes: a population-based cohort study. Diabetologia. 2017 May; 60(5):843-853. PMID: 28224192.
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  45. Gall H, Felix JF, Schneck FK, Milger K, Sommer N, Voswinckel R, Franco OH, Hofman A, Schermuly RT, Weissmann N, Grimminger F, Seeger W, Ghofrani HA. The Giessen Pulmonary Hypertension Registry: Survival in pulmonary hypertension subgroups. J Heart Lung Transplant. 2017 Sep; 36(9):957-967. PMID: 28302503.
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  46. Grootendorst-van Mil NH, Steegers-Theunissen RP, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Brighter children? The association between seasonality of birth and child IQ in a population-based birth cohort. BMJ Open. 2017 Feb 17; 7(2):e012406. PMID: 28213594.
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  47. Bos D, Vernooij MW, Shahzad R, Kavousi M, Hofman A, van Walsum T, Deckers JW, Ikram MA, Heeringa J, Franco OH, van der Lugt A, Leening MJ. Epicardial Fat Volume and the Risk of Atrial Fibrillation in the General Population Free of Cardiovascular Disease. JACC Cardiovasc Imaging. 2017 Feb 09. PMID: 28216004.
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  48. Braun KVE, Dhana K, de Vries PS, Voortman T, van Meurs JBJ, Uitterlinden AG, Hofman A, Hu FB, Franco OH, Dehghan A. Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study. Clin Epigenetics. 2017; 9:15. PMID: 28194238.
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  49. Verlinden VJA, van der Geest JN, Hofman A, Niessen WJ, van der Lugt A, Vernooij MW, Ikram MA. Brain MRI-markers Associate Differentially with Cognitive Versus Functional Decline Leading to Dementia. J Am Geriatr Soc. 2017 Jun; 65(6):1258-1266. PMID: 28165615.
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  50. van der Lee SJ, Roshchupkin GV, Adams HH, Schmidt H, Hofer E, Saba Y, Schmidt R, Hofman A, Amin N, van Duijn CM, Vernooij MW, Ikram MA, Niessen WJ. Gray matter heritability in family-based and population-based studies using voxel-based morphometry. Hum Brain Mapp. 2017 May; 38(5):2408-2423. PMID: 28145022.
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  51. Miliku K, Mesu A, Franco OH, Hofman A, Steegers EA, Jaddoe VW. Maternal and Fetal Folate, Vitamin B12, and Homocysteine Concentrations and Childhood Kidney Outcomes. Am J Kidney Dis. 2017 Apr; 69(4):521-530. PMID: 28143670.
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  52. Joachim N, Colijn JM, Kifley A, Lee KE, Buitendijk GHS, Klein BEK, Myers CE, Meuer SM, Tan AG, Holliday EG, Attia J, Liew G, Iyengar SK, de Jong PTVM, Hofman A, Vingerling JR, Mitchell P, Klaver CCW, Klein R, Wang JJ. Five-year progression of unilateral age-related macular degeneration to bilateral involvement: the Three Continent AMD Consortium report. Br J Ophthalmol. 2017 Sep; 101(9):1185-1192. PMID: 28108569.
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  53. Milic J, Saavedra Perez H, Zuurbier LA, Boelen PA, Rietjens JA, Hofman A, Tiemeier H. The Longitudinal and Cross-Sectional Associations of Grief and Complicated Grief With Sleep Quality in Older Adults. Behav Sleep Med. 2017 Jan 20; 1-12. PMID: 28107032.
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  55. Freak-Poli R, Castro Lima G, Direk N, Jaspers L, Pitts M, Hofman A, Tiemeier H. Corrigendum: Happiness, rather than depression, is associated with sexual behaviour in partnered older adults. Age Ageing. 2017 Jan 19. PMID: 28104603.
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  56. Freak-Poli R, De Castro Lima G, Direk N, Jaspers L, Pitts M, Hofman A, Tiemeier H. Happiness, rather than depression, is associated with sexual behaviour in partnered older adults. Age Ageing. 2017 01 19; 46(1):101-107. PMID: 28104602.
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  57. de Vlaming R, Okbay A, Rietveld CA, Johannesson M, Magnusson PK, Uitterlinden AG, van Rooij FJ, Hofman A, Groenen PJ, Thurik AR, Koellinger PD. Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies. PLoS Genet. 2017 Jan; 13(1):e1006495. PMID: 28095416.
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  60. Darweesh SK, Verlinden VJ, Stricker BH, Hofman A, Koudstaal PJ, Ikram MA. Trajectories of prediagnostic functioning in Parkinson's disease. Brain. 2017 Feb; 140(Pt 2):429-441. PMID: 28082300.
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  61. Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SL, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G. The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017 Jan 10; 9(1):209-246. PMID: 28077804.
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  62. Warner SC, van Meurs JB, Schiphof D, Bierma-Zeinstra SM, Hofman A, Uitterlinden AG, Richardson H, Jenkins W, Doherty M, Valdes AM. Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene. Eur J Hum Genet. 2017 Apr; 25(4):446-451. PMID: 28051079.
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  65. Brahimaj A, Ligthart S, Ikram MA, Hofman A, Franco OH, Sijbrands EJ, Kavousi M, Dehghan A. Serum Levels of Apolipoproteins and Incident Type 2 Diabetes: A Prospective Cohort Study. Diabetes Care. 2017 Mar; 40(3):346-351. PMID: 28031419.
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  69. Roshchupkin GV, Gutman BA, Vernooij MW, Jahanshad N, Martin NG, Hofman A, McMahon KL, van der Lee SJ, van Duijn CM, de Zubicaray GI, Uitterlinden AG, Wright MJ, Niessen WJ, Thompson PM, Ikram MA, Adams HH. Heritability of the shape of subcortical brain structures in the general population. Nat Commun. 2016 Dec 15; 7:13738. PMID: 27976715.
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  73. Krishnadath IS, Toelsie JR, Hofman A, Jaddoe VW. Ethnic disparities in the prevalence of metabolic syndrome and its risk factors in the Suriname Health Study: a cross-sectional population study. BMJ Open. 2016 Dec 07; 6(12):e013183. PMID: 27927663.
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  74. Koolhaas CM, Dhana K, van Rooij FJ, Kocevska D, Hofman A, Franco OH, Tiemeier H. Sedentary time assessed by actigraphy and mortality: The Rotterdam Study. Prev Med. 2017 Feb; 95:59-65. PMID: 27939262.
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  75. Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van 't Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ, Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, 't Hoen PA, Franke L, Heijmans BT. Disease variants alter transcription factor levels and methylation of their binding sites. Nat Genet. 2017 Jan; 49(1):131-138. PMID: 27918535.
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  78. Saberi Hosnijeh F, Zuiderwijk ME, Versteeg M, Smeele HT, Hofman A, Uitterlinden AG, Agricola R, Oei EH, Waarsing JH, Bierma-Zeinstra SM, van Meurs JB. Cam Deformity and Acetabular Dysplasia as Risk Factors for Hip Osteoarthritis. Arthritis Rheumatol. 2017 Jan; 69(1):86-93. PMID: 27696746.
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  79. Jaspers L, Kavousi M, Erler NS, Hofman A, Laven JS, Franco OH. Fertile lifespan characteristics and all-cause and cause-specific mortality among postmenopausal women: the Rotterdam Study. Fertil Steril. 2017 Feb; 107(2):448-456.e1. PMID: 27919437.
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  80. Ikram MA, Vernooij MW, Roshchupkin GV, Hofman A, van Duijn CM, Uitterlinden AG, Niessen WJ, Hintzen RQ, Adams HH. Genetic susceptibility to multiple sclerosis: Brain structure and cognitive function in the general population. Mult Scler. 2016 Dec 01; 1352458516682104. PMID: 28273768.
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  81. Tideman JW, Snabel MC, Tedja MS, van Rijn GA, Wong KT, Kuijpers RW, Vingerling JR, Hofman A, Buitendijk GH, Keunen JE, Boon CJ, Geerards AJ, Luyten GP, Verhoeven VJ, Klaver CC. Association of Axial Length With Risk of Uncorrectable Visual Impairment for Europeans With Myopia. JAMA Ophthalmol. 2016 Dec 01; 134(12):1355-1363. PMID: 27768171.
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  82. Mutlu U, Ikram MA, Hofman A, de Jong PT, Uitterlinden AG, Klaver CC, Ikram MK. Vitamin D and retinal microvascular damage: The Rotterdam Study. Medicine (Baltimore). 2016 Dec; 95(49):e5477. PMID: 27930528.
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  83. Chaker L, Sedaghat S, Hoorn EJ, Elzen WP, Gussekloo J, Hofman A, Ikram MA, Franco OH, Dehghan A, Peeters RP. The association of thyroid function and the risk of kidney function decline: a population-based cohort study. Eur J Endocrinol. 2016 Dec; 175(6):653-660. PMID: 27926474.
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  84. de Jonge EA, Kiefte-de Jong JC, Hofman A, Uitterlinden AG, Kieboom BC, Voortman T, Franco OH, Rivadeneira F. Dietary patterns explaining differences in bone mineral density and hip structure in the elderly: the Rotterdam Study. Am J Clin Nutr. 2017 Jan; 105(1):203-211. PMID: 27903522.
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  99. de Vries PS, van Herpt TT, Ligthart S, Hofman A, Ikram MA, van Hoek M, Sijbrands EJ, Franco OH, de Maat MP, Leebeek FW, Dehghan A. ADAMTS13 activity as a novel risk factor for incident type 2 diabetes mellitus: a population-based cohort study. Diabetologia. 2017 Feb; 60(2):280-286. PMID: 27787621.
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  105. Selwaness M, Hameeteman R, Van 't Klooster R, Van den Bouwhuijsen Q, Hofman A, Franco OH, Niessen WJ, Klein S, Vernooij MW, Van der Lugt A, Wentzel JJ. Determinants of carotid atherosclerotic plaque burden in a stroke-free population. Atherosclerosis. 2016 Dec; 255:186-192. PMID: 27806835.
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  106. Dhana K, Koolhaas CM, Berghout MA, Peeters A, Ikram MA, Tiemeier H, Hofman A, Nusselder W, Franco OH. Physical activity types and life expectancy with and without cardiovascular disease: the Rotterdam Study. J Public Health (Oxf). 2016 Oct 13. PMID: 27738126.
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  107. Schalekamp-Timmermans S, Cornette J, Hofman A, Helbing WA, Jaddoe VW, Steegers EA, Verburg BO. In utero origin of sex-related differences in future cardiovascular disease. Biol Sex Differ. 2016; 7:55. PMID: 27757222.
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  108. Direk N, Dekker MJ, Luik AI, Kirschbaum C, de Rijke YB, Hofman A, Hoogendijk WJ, Tiemeier H. The Very Low-Dose Dexamethasone Suppression Test in the General Population: A Cross-Sectional Study. PLoS One. 2016; 11(10):e0164348. PMID: 27736954.
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  109. Sonneveld MA, Franco OH, Ikram MA, Hofman A, Kavousi M, de Maat MP, Leebeek FW. Von Willebrand Factor, ADAMTS13, and the Risk of Mortality: The Rotterdam Study. Arterioscler Thromb Vasc Biol. 2016 Dec; 36(12):2446-2451. PMID: 27737864.
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  110. Wolters FJ, Mattace-Raso FU, Koudstaal PJ, Hofman A, Ikram MA. Orthostatic Hypotension and the Long-Term Risk of Dementia: A Population-Based Study. PLoS Med. 2016 Oct; 13(10):e1002143. PMID: 27727284.
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  138. Khawaja AP, Springelkamp H, Creuzot-Garcher C, Delcourt C, Hofman A, Höhn R, Iglesias AI, Wolfs RC, Korobelnik JF, Silva R, Topouzis F, Williams KM, Bron AM, Buitendijk GH, Cachulo MD, Cougnard-Grégoire A, Dartigues JF, Hammond CJ, Pfeiffer N, Salonikiou A, van Duijn CM, Vingerling JR, Luben RN, Mirshahi A, Lamparter J, Klaver CC, Jansonius NM, Foster PJ. Associations with intraocular pressure across Europe: The European Eye Epidemiology (E3) Consortium. Eur J Epidemiol. 2016 Nov; 31(11):1101-1111. PMID: 27613171.
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  139. Chaker L, Baumgartner C, den Elzen WP, Collet TH, Ikram MA, Blum MR, Dehghan A, Drechsler C, Luben RN, Portegies ML, Iervasi G, Medici M, Stott DJ, Dullaart RP, Ford I, Bremner A, Newman AB, Wanner C, Sgarbi JA, Dörr M, Longstreth WT, Psaty BM, Ferrucci L, Maciel RM, Westendorp RG, Jukema JW, Ceresini G, Imaizumi M, Hofman A, Bakker SJ, Franklyn JA, Khaw KT, Bauer DC, Walsh JP, Razvi S, Gussekloo J, Völzke H, Franco OH, Cappola AR, Rodondi N, Peeters RP. Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis. J Clin Endocrinol Metab. 2016 Nov; 101(11):4270-4282. PMID: 27603906.
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  140. van der Plaat DA, de Jong K, Lahousse L, Faiz A, Vonk JM, van Diemen CC, Nedeljkovic I, Amin N, Brusselle GG, Hofman A, Brandsma CA, Bossé Y, Sin DD, Nickle DC, van Duijn CM, Postma DS, Boezen HM. Genome-wide association study on the FEV1/FVC ratio in never-smokers identifies HHIP and FAM13A. J Allergy Clin Immunol. 2017 Feb; 139(2):533-540. PMID: 27612410.
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  141. Chaker L, van den Berg ME, Niemeijer MN, Franco OH, Dehghan A, Hofman A, Rijnbeek PR, Deckers JW, Eijgelsheim M, Stricker BH, Peeters RP. Thyroid Function and Sudden Cardiac Death: A Prospective Population-Based Cohort Study. Circulation. 2016 Sep 06; 134(10):713-22. PMID: 27601558.
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  142. Roshchupkin GV, Adams HH, van der Lee SJ, Vernooij MW, van Duijn CM, Uitterlinden AG, van der Lugt A, Hofman A, Niessen WJ, Ikram MA. Fine-mapping the effects of Alzheimer's disease risk loci on brain morphology. Neurobiol Aging. 2016 Dec; 48:204-211. PMID: 27718423.
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  143. Chaker L, Korevaar TI, Medici M, Uitterlinden AG, Hofman A, Dehghan A, Franco OH, Peeters RP. Thyroid Function Characteristics and Determinants: The Rotterdam Study. Thyroid. 2016 Sep; 26(9):1195-204. PMID: 27484151.
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  144. Aarts N, Noordam R, Hofman A, Tiemeier H, Stricker BH, Visser LE. Self-reported indications for antidepressant use in a population-based cohort of middle-aged and elderly. Int J Clin Pharm. 2016 Oct; 38(5):1311-7. PMID: 27586370.
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  145. Pavlovic J, Greenland P, Deckers JW, Brugts JJ, Kavousi M, Dhana K, Ikram MA, Hofman A, Stricker BH, Franco OH, Leening MJ. Comparison of ACC/AHA and ESC Guideline Recommendations Following Trial Evidence for Statin Use in Primary Prevention of Cardiovascular Disease: Results From the Population-Based Rotterdam Study. JAMA Cardiol. 2016 Sep 01; 1(6):708-13. PMID: 27439175.
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  146. Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, Veeraraghavan N, Walter K, Chen L, Yanek L, Becker LC, Peloso GM, Wakabayashi A, Kals M, Metspalu A, Esko T, Fox K, Wallace R, Franceschini N, Matijevic N, Rice KM, Bartz TM, Lyytikäinen LP, Kähönen M, Lehtimäki T, Raitakari OT, Li-Gao R, Mook-Kanamori DO, Lettre G, van Duijn CM, Franco OH, Rich SS, Rivadeneira F, Hofman A, Uitterlinden AG, Wilson JG, Psaty BM, Soranzo N, Dehghan A, Boerwinkle E, Zhang X, Johnson AD, O'Donnell CJ, Johnsen JM, Reiner AP, Ganesh SK, Sankaran VG. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. Am J Hum Genet. 2016 Sep 01; 99(3):785. PMID: 27588453.
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  147. Noordam R, Aarts N, Peeters RP, Hofman A, Stricker BH, Visser LE. Selective Serotonin Reuptake Inhibitors Decrease Pancreatic Insulin Secretion in Older Adults and Increase the Risk of Insulin Dependence in Type 2 Diabetes Patients. J Clin Psychiatry. 2016 Sep; 77(9):e1124-e1129. PMID: 27487004.
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  148. Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE, Deshmukh HA, Evans DS, Feng Q, Li X, Smit RA, Smith AV, Sun F, Taylor KD, Arnold AM, Barnes MR, Barratt BJ, Betteridge J, Boekholdt SM, Boerwinkle E, Buckley BM, Chen YI, de Craen AJ, Cummings SR, Denny JC, Dubé MP, Durrington PN, Eiriksdottir G, Ford I, Guo X, Harris TB, Heckbert SR, Hofman A, Hovingh GK, Kastelein JJ, Launer LJ, Liu CT, Liu Y, Lumley T, McKeigue PM, Munroe PB, Neil A, Nickerson DA, Nyberg F, O'Brien E, O'Donnell CJ, Post W, Poulter N, Vasan RS, Rice K, Rich SS, Rivadeneira F, Sattar N, Sever P, Shaw-Hawkins S, Shields DC, Slagboom PE, Smith NL, Smith JD, Sotoodehnia N, Stanton A, Stott DJ, Stricker BH, Stürmer T, Uitterlinden AG, Wei WQ, Westendorp RG, Whitsel EA, Wiggins KL, Wilke RA, Ballantyne CM, Colhoun HM, Cupples LA, Franco OH, Gudnason V, Hitman G, Palmer CN, Psaty BM, Ridker PM, Stafford JM, Stein CM, Tardif JC, Caulfield MJ, Jukema JW, Rotter JI, Krauss RM. Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. J Med Genet. 2016 Dec; 53(12):835-845. PMID: 27587472.
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  149. Koole A, Nagtegaal AP, Homans NC, Hofman A, Baatenburg de Jong RJ, Goedegebure A. Using the Digits-In-Noise Test to Estimate Age-Related Hearing Loss. Ear Hear. 2016 Sep-Oct; 37(5):508-13. PMID: 26871876.
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  150. van der Laan SW, Fall T, Soumaré A, Teumer A, Sedaghat S, Baumert J, Zabaneh D, van Setten J, Isgum I, Galesloot TE, Arpegård J, Amouyel P, Trompet S, Waldenberger M, Dörr M, Magnusson PK, Giedraitis V, Larsson A, Morris AP, Felix JF, Morrison AC, Franceschini N, Bis JC, Kavousi M, O'Donnell C, Drenos F, Tragante V, Munroe PB, Malik R, Dichgans M, Worrall BB, Erdmann J, Nelson CP, Samani NJ, Schunkert H, Marchini J, Patel RS, Hingorani AD, Lind L, Pedersen NL, de Graaf J, Kiemeney LA, Baumeister SE, Franco OH, Hofman A, Uitterlinden AG, Koenig W, Meisinger C, Peters A, Thorand B, Jukema JW, Eriksen BO, Toft I, Wilsgaard T, Onland-Moret NC, van der Schouw YT, Debette S, Kumari M, Svensson P, van der Harst P, Kivimaki M, Keating BJ, Sattar N, Dehghan A, Reiner AP, Ingelsson E, den Ruijter HM, de Bakker PI, Pasterkamp G, Ärnlöv J, Holmes MV, Asselbergs FW. Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study. J Am Coll Cardiol. 2016 Aug 30; 68(9):934-45. PMID: 27561768.
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  151. Huan T, Joehanes R, Schurmann C, Schramm K, Pilling LC, Peters MJ, Mägi R, DeMeo D, O'Connor GT, Ferrucci L, Teumer A, Homuth G, Biffar R, Völker U, Herder C, Waldenberger M, Peters A, Zeilinger S, Metspalu A, Hofman A, Uitterlinden AG, Hernandez DG, Singleton AB, Bandinelli S, Munson PJ, Lin H, Benjamin EJ, Esko T, Grabe HJ, Prokisch H, van Meurs JB, Melzer D, Levy D. A Whole-Blood Transcriptome Meta-Analysis Identifies Gene Expression Signatures of Cigarette Smoking. Hum Mol Genet. 2016 Aug 29. PMID: 27577875.
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  152. de Jonge EA, Rivadeneira F, Erler NS, Hofman A, Uitterlinden AG, Franco OH, Kiefte-de Jong JC. Dietary patterns in an elderly population and their relation with bone mineral density: the Rotterdam Study. Eur J Nutr. 2016 Aug 24. PMID: 27557817.
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  153. Wolff L, Bos D, Murad SD, Franco OH, Krestin GP, Hofman A, Vernooij MW, van der Lugt A. Liver fat is related to cardiovascular risk factors and subclinical vascular disease: the Rotterdam Study. Eur Heart J Cardiovasc Imaging. 2016 Dec; 17(12):1361-1367. PMID: 27550661.
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  154. Weiss A, Baselmans BM, Hofer E, Yang J, Okbay A, Lind PA, Miller MB, Nolte IM, Zhao W, Hagenaars SP, Hottenga JJ, Matteson LK, Snieder H, Faul JD, Hartman CA, Boyle PA, Tiemeier H, Mosing MA, Pattie A, Davies G, Liewald DC, Schmidt R, De Jager PL, Heath AC, Jokela M, Starr JM, Oldehinkel AJ, Johannesson M, Cesarini D, Hofman A, Harris SE, Smith JA, Keltikangas-Järvinen L, Pulkki-Råback L, Schmidt H, Smith J, Iacono WG, McGue M, Bennett DA, Pedersen NL, Magnusson PK, Deary IJ, Martin NG, Boomsma DI, Bartels M, Luciano M. Personality Polygenes, Positive Affect, and Life Satisfaction. Twin Res Hum Genet. 2016 Oct; 19(5):407-17. PMID: 27546527.
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  155. van den Bouwhuijsen QJ, Selwaness M, Tang H, Niessen WJ, Hofman A, Franco OH, van der Lugt A, Vernooij MW. Change in Carotid Intraplaque Hemorrhage in Community-dwelling Subjects: A Follow-up Study Using Serial MR Imaging. Radiology. 2017 Feb; 282(2):526-533. PMID: 27541684.
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  156. Tiller D, Ittermann T, Greiser KH, Meisinger C, Agger C, Hofman A, Thuesen B, Linneberg A, Peeters R, Franco O, Heier M, Kluttig A, Werdan K, Stricker B, Schipf S, Markus M, Dörr M, Völzke H, Haerting J. Association of Serum Thyrotropin with Anthropometric Markers of Obesity in the General Population. Thyroid. 2016 Sep; 26(9):1205-14. PMID: 27393002.
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  157. Amin N, Belonogova NM, Jovanova O, Brouwer RW, van Rooij JG, van den Hout MC, Svishcheva GR, Kraaij R, Zorkoltseva IV, Kirichenko AV, Hofman A, Uitterlinden AG, van IJcken WF, Tiemeier H, Axenovich TI, van Duijn CM. Nonsynonymous Variation in NKPD1 Increases Depressive Symptoms in European Populations. Biol Psychiatry. 2017 Apr 15; 81(8):702-707. PMID: 27745872.
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  158. Mutlu U, Cremers LG, de Groot M, Hofman A, Niessen WJ, van der Lugt A, Klaver CC, Ikram MA, Vernooij MW, Ikram MK. Retinal microvasculature and white matter microstructure: The Rotterdam Study. Neurology. 2016 Sep 06; 87(10):1003-10. PMID: 27511186.
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  159. Mirza SS, Ikram MA, Bos D, Mihaescu R, Hofman A, Tiemeier H. Mild cognitive impairment and risk of depression and anxiety: A population-based study. Alzheimers Dement. 2017 Feb; 13(2):130-139. PMID: 27520773.
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  160. Zhou K, Yee SW, Seiser EL, van Leeuwen N, Tavendale R, Bennett AJ, Groves CJ, Coleman RL, van der Heijden AA, Beulens JW, de Keyser CE, Zaharenko L, Rotroff DM, Out M, Jablonski KA, Chen L, Javorský M, Židzik J, Levin AM, Williams LK, Dujic T, Semiz S, Kubo M, Chien HC, Maeda S, Witte JS, Wu L, Tkác I, Kooy A, van Schaik RHN, Stehouwer CDA, Logie L, Sutherland C, Klovins J, Pirags V, Hofman A, Stricker BH, Motsinger-Reif AA, Wagner MJ, Innocenti F, 't Hart LM, Holman RR, McCarthy MI, Hedderson MM, Palmer CNA, Florez JC, Giacomini KM, Pearson ER. Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin. Nat Genet. 2016 Sep; 48(9):1055-1059. PMID: 27500523; PMCID: PMC5007158.
  161. Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, Veeraraghavan N, Walter K, Chen L, Yanek L, Becker LC, Peloso GM, Wakabayashi A, Kals M, Metspalu A, Esko T, Fox K, Wallace R, Franceshini N, Matijevic N, Rice KM, Bartz TM, Lyytikäinen LP, Kähönen M, Lehtimäki T, Raitakari OT, Li-Gao R, Mook-Kanamori DO, Lettre G, van Duijn CM, Franco OH, Rich SS, Rivadeneira F, Hofman A, Uitterlinden AG, Wilson JG, Psaty BM, Soranzo N, Dehghan A, Boerwinkle E, Zhang X, Johnson AD, O'Donnell CJ, Johnsen JM, Reiner AP, Ganesh SK, Sankaran VG. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. Am J Hum Genet. 2016 Aug 04; 99(2):481-8. PMID: 27486782; PMCID: PMC4974169 [Available on 02/04/17].
  162. Sedaghat S, Cremers LG, de Groot M, Hofman A, van der Lugt A, Niessen WJ, Franco OH, Dehghan A, Ikram MA, Vernooij MW. Lower microstructural integrity of brain white matter is related to higher mortality. Neurology. 2016 Aug 30; 87(9):927-34. PMID: 27488598.
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  163. Sedaghat S, de Vries PS, Boender J, Sonneveld MA, Hoorn EJ, Hofman A, de Maat MP, Franco OH, Ikram MA, Leebeek FW, Dehghan A. von Willebrand Factor, ADAMTS13 Activity, and Decline in Kidney Function: A Population-Based Cohort Study. Am J Kidney Dis. 2016 Nov; 68(5):726-732. PMID: 27497525.
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  164. Akoudad S, Wolters FJ, Viswanathan A, de Bruijn RF, van der Lugt A, Hofman A, Koudstaal PJ, Ikram MA, Vernooij MW. Association of Cerebral Microbleeds With Cognitive Decline and Dementia. JAMA Neurol. 2016 Aug 01; 73(8):934-43. PMID: 27271785.
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  165. Okbay A, Baselmans BM, Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonzalez JR, Haitjema S, Karlsson R, van der Laan SW, Ladwig KH, Lahti J, van der Lee SJ, Lind PA, Liu T, Matteson L, Mihailov E, Miller MB, Minica CC, Nolte IM, Mook-Kanamori D, van der Most PJ, Oldmeadow C, Qian Y, Raitakari O, Rawal R, Realo A, Rueedi R, Schmidt B, Smith AV, Stergiakouli E, Tanaka T, Taylor K, Thorleifsson G, Wedenoja J, Wellmann J, Westra HJ, Willems SM, Zhao W, Amin N, Bakshi A, Bergmann S, Bjornsdottir G, Boyle PA, Cherney S, Cox SR, Davies G, Davis OS, Ding J, Direk N, Eibich P, Emeny RT, Fatemifar G, Faul JD, Ferrucci L, Forstner AJ, Gieger C, Gupta R, Harris TB, Harris JM, Holliday EG, Hottenga JJ, Jager PL, Kaakinen MA, Kajantie E, Karhunen V, Kolcic I, Kumari M, Launer LJ, Franke L, Li-Gao R, Liewald DC, Koini M, Loukola A, Marques-Vidal P, Montgomery GW, Mosing MA, Paternoster L, Pattie A, Petrovic KE, Pulkki-Råback L, Quaye L, Räikkönen K, Rudan I, Scott RJ, Smith JA, Sutin AR, Trzaskowski M, Vinkhuyzen AE, Yu L, Zabaneh D, Attia JR, Bennett DA, Berger K, Bertram L, Boomsma DI, Snieder H, Chang SC, Cucca F, Deary IJ, van Duijn CM, Eriksson JG, Bültmann U, de Geus EJ, Groenen PJ, Gudnason V, Hansen T, Hartman CA, Haworth CM, Hayward C, Heath AC, Hinds DA, Hyppönen E, Iacono WG, Järvelin MR, Jöckel KH, Kaprio J, Kardia SL, Keltikangas-Järvinen L, Kraft P, Kubzansky LD, Lehtimäki T, Magnusson PK, Martin NG, McGue M, Metspalu A, Mills M, de Mutsert R, Oldehinkel AJ, Pasterkamp G, Pedersen NL, Plomin R, Polasek O, Power C, Rich SS, Rosendaal FR, den Ruijter HM, Schlessinger D, Schmidt H, Svento R, Schmidt R, Alizadeh BZ, Sørensen TI, Spector TD, Starr JM, Stefansson K, Steptoe A, Terracciano A, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tiemeier H, Uitterlinden AG, Vollenweider P, Wagner GG, Weir DR, Yang J, Conley DC, Smith GD, Hofman A, Johannesson M, Laibson DI, Medland SE, Meyer MN, Pickrell JK, Esko T, Krueger RF, Beauchamp JP, Koellinger PD, Benjamin DJ, Bartels M, Cesarini D. Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses. Nat Genet. 2016 Jul 27; 48(8):970. PMID: 27463399.
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  166. van Rheenen W, Shatunov A, Dekker AM, McLaughlin RL, Diekstra FP, Pulit SL, van der Spek RA, Võsa U, de Jong S, Robinson MR, Yang J, Fogh I, van Doormaal PT, Tazelaar GH, Koppers M, Blokhuis AM, Sproviero W, Jones AR, Kenna KP, van Eijk KR, Harschnitz O, Schellevis RD, Brands WJ, Medic J, Menelaou A, Vajda A, Ticozzi N, Lin K, Rogelj B, Vrabec K, Ravnik-Glavac M, Koritnik B, Zidar J, Leonardis L, Grošelj LD, Millecamps S, Salachas F, Meininger V, de Carvalho M, Pinto S, Mora JS, Rojas-García R, Polak M, Chandran S, Colville S, Swingler R, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Pittman A, Sidle K, Fratta P, Malaspina A, Topp S, Petri S, Abdulla S, Drepper C, Sendtner M, Meyer T, Ophoff RA, Staats KA, Wiedau-Pazos M, Lomen-Hoerth C, Van Deerlin VM, Trojanowski JQ, Elman L, McCluskey L, Basak AN, Tunca C, Hamzeiy H, Parman Y, Meitinger T, Lichtner P, Radivojkov-Blagojevic M, Andres CR, Maurel C, Bensimon G, Landwehrmeyer B, Brice A, Payan CA, Saker-Delye S, Dürr A, Wood NW, Tittmann L, Lieb W, Franke A, Rietschel M, Cichon S, Nöthen MM, Amouyel P, Tzourio C, Dartigues JF, Uitterlinden AG, Rivadeneira F, Estrada K, Hofman A, Curtis C, Blauw HM, van der Kooi AJ, de Visser M, Goris A, Weber M, Shaw CE, Smith BN, Pansarasa O, Cereda C, Del Bo R, Comi GP, D'Alfonso S, Bertolin C, Sorarù G, Mazzini L, Pensato V, Gellera C, Tiloca C, Ratti A, Calvo A, Moglia C, Brunetti M, Arcuti S, Capozzo R, Zecca C, Lunetta C, Penco S, Riva N, Padovani A, Filosto M, Muller B, Stuit RJ, Blair I, Zhang K, McCann EP, Fifita JA, Nicholson GA, Rowe DB, Pamphlett R, Kiernan MC, Grosskreutz J, Witte OW, Ringer T, Prell T, Stubendorff B, Kurth I, Hübner CA, Leigh PN, Casale F, Chio A, Beghi E, Pupillo E, Tortelli R, Logroscino G, Powell J, Ludolph AC, Weishaupt JH, Robberecht W, Van Damme P, Franke L, Pers TH, Brown RH, Glass JD, Landers JE, Hardiman O, Andersen PM, Corcia P, Vourc'h P, Silani V, Wray NR, Visscher PM, de Bakker PI, van Es MA, Pasterkamp RJ, Lewis CM, Breen G, Al-Chalabi A, van den Berg LH, Veldink JH. Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. Nat Genet. 2016 Sep; 48(9):1043-8. PMID: 27455348.
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  167. Dhana K, Nano J, Ligthart S, Peeters A, Hofman A, Nusselder W, Dehghan A, Franco OH. Obesity and Life Expectancy with and without Diabetes in Adults Aged 55 Years and Older in the Netherlands: A Prospective Cohort Study. PLoS Med. 2016 Jul; 13(7):e1002086. PMID: 27433939; PMCID: PMC4951120.
  168. Aarts N, Zuurbier LA, Noordam R, Hofman A, Tiemeier H, Stricker BH, Visser LE. Use of Selective Serotonin Reuptake Inhibitors and Sleep Quality: A Population-Based Study. J Clin Sleep Med. 2016 Jul 15; 12(7):989-95. PMID: 27092698; PMCID: PMC4919000 [Available on 01/15/17].
  169. Portegies ML, Wolters FJ, Hofman A, Ikram MK, Koudstaal PJ, Ikram MA. Prestroke Vascular Pathology and the Risk of Recurrent Stroke and Poststroke Dementia. Stroke. 2016 Aug; 47(8):2119-22. PMID: 27418596.
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  170. van 't Hof FN, Ruigrok YM, Lee CH, Ripke S, Anderson G, de Andrade M, Baas AF, Blankensteijn JD, Böttinger EP, Bown MJ, Broderick J, Bijlenga P, Carrell DS, Crawford DC, Crosslin DR, Ebeling C, Eriksson JG, Fornage M, Foroud T, von Und Zu Fraunberg M, Friedrich CM, Gaál EI, Gottesman O, Guo DC, Harrison SC, Hernesniemi J, Hofman A, Inoue I, Jääskeläinen JE, Jones GT, Kiemeney LA, Kivisaari R, Ko N, Koskinen S, Kubo M, Kullo IJ, Kuivaniemi H, Kurki MI, Laakso A, Lai D, Leal SM, Lehto H, LeMaire SA, Low SK, Malinowski J, McCarty CA, Milewicz DM, Mosley TH, Nakamura Y, Nakaoka H, Niemelä M, Pacheco J, Peissig PL, Pera J, Rasmussen-Torvik L, Ritchie MD, Rivadeneira F, van Rij AM, Santos-Cortez RL, Saratzis A, Slowik A, Takahashi A, Tromp G, Uitterlinden AG, Verma SS, Vermeulen SH, Wang GT, Han B, Rinkel GJ, de Bakker PI. Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms. J Am Heart Assoc. 2016 Jul 14; 5(7). PMID: 27418160.
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  171. Praagman J, de Jonge EA, Kiefte-de Jong JC, Beulens JW, Sluijs I, Schoufour JD, Hofman A, van der Schouw YT, Franco OH. Dietary Saturated Fatty Acids and Coronary Heart Disease Risk in a Dutch Middle-Aged and Elderly Population. Arterioscler Thromb Vasc Biol. 2016 Sep; 36(9):2011-8. PMID: 27417581.
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  172. Voortman T, Leermakers ET, Franco OH, Jaddoe VW, Moll HA, Hofman A, van den Hooven EH, Kiefte-de Jong JC. A priori and a posteriori dietary patterns at the age of 1 year and body composition at the age of 6 years: the Generation R Study. Eur J Epidemiol. 2016 Aug; 31(8):775-83. PMID: 27384175; PMCID: PMC5005385.
  173. Homans NC, Metselaar RM, Dingemanse JG, van der Schroeff MP, Brocaar MP, Wieringa MH, Baatenburg de Jong RJ, Hofman A, Goedegebure A. Prevalence of age-related hearing loss, including sex differences, in older adults in a large cohort study. Laryngoscope. 2017 Mar; 127(3):725-730. PMID: 27377351.
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  174. Darweesh SK, Wolters FJ, Hofman A, Stricker BH, Koudstaal PJ, Ikram MA. Simple Test of Manual Dexterity Can Help to Identify Persons at High Risk for Neurodegenerative Diseases in the Community. J Gerontol A Biol Sci Med Sci. 2017 Jan; 72(1):75-81. PMID: 27371953.
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  175. Toemen L, de Jonge LL, Gishti O, van Osch-Gevers L, Taal HR, Steegers EA, Hofman A, Helbing WA, Jaddoe VW. Longitudinal growth during fetal life and infancy and cardiovascular outcomes at school-age. J Hypertens. 2016 Jul; 34(7):1396-406. PMID: 27115338.
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  176. Bergen NE, Schalekamp-Timmermans S, Jaddoe VW, Hofman A, Lindemans J, Russcher H, Tiemeier H, Steegers-Theunissen RP, Steegers EA. Maternal and Neonatal Markers of the Homocysteine Pathway and Fetal Growth: The Generation R Study. Paediatr Perinat Epidemiol. 2016 07; 30(4):386-96. PMID: 27271101.
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  177. van Loon J, Dehghan A, Weihong T, Trompet S, McArdle WL, Asselbergs FW, Chen MH, Lopez LM, Huffman JE, Leebeek FW, Basu S, Stott DJ, Rumley A, Gansevoort RT, Davies G, Wilson JJ, Witteman JC, Cao X, de Craen AJ, Bakker SJ, Psaty BM, Starr JM, Hofman A, Jukema JW, Deary IJ, Hayward C, van der Harst P, Lowe GD, Folsom AR, Strachan DP, Smith N, de Maat MP, O'Donnell C. Genome-wide association studies identify genetic loci for low von Willebrand factor levels. Eur J Hum Genet. 2016 Jul; 24(7):1096. PMID: 27307114.
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  178. de Kruijf M, Stolk L, Zillikens MC, de Rijke YB, Bierma-Zeinstra SM, Hofman A, Huygen FJ, Uitterlinden AG, van Meurs JB. Lower sex hormone levels are associated with more chronic musculoskeletal pain in community-dwelling elderly women. Pain. 2016 07; 157(7):1425-31. PMID: 27331348.
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  179. Jelena Vidakovic A, Santos S, Williams MA, Duijts L, Hofman A, Demmelmair H, Koletzko B, Jaddoe VW, Gaillard R. Maternal plasma n-3 and n-6 polyunsaturated fatty acid concentrations during pregnancy and subcutaneous fat mass in infancy. Obesity (Silver Spring). 2016 Aug; 24(8):1759-66. PMID: 27356181.
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  180. Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Lu Y, Mägi R, Mihailov E, Pers TH, Rüeger S, Teumer A, Ehret GB, Ferreira T, Heard-Costa NL, Karjalainen J, Lagou V, Mahajan A, Neinast MD, Prokopenko I, Simino J, Teslovich TM, Jansen R, Westra HJ, White CC, Absher D, Ahluwalia TS, Ahmad S, Albrecht E, Alves AC, Bragg-Gresham JL, de Craen AJ, Bis JC, Bonnefond A, Boucher G, Cadby G, Cheng YC, Chiang CW, Delgado G, Demirkan A, Dueker N, Eklund N, Eiriksdottir G, Eriksson J, Feenstra B, Fischer K, Frau F, Galesloot TE, Geller F, Goel A, Gorski M, Grammer TB, Gustafsson S, Haitjema S, Hottenga JJ, Huffman JE, Jackson AU, Jacobs KB, Johansson Å, Kaakinen M, Kleber ME, Lahti J, Mateo Leach I, Lehne B, Liu Y, Lo KS, Lorentzon M, Luan J, Madden PA, Mangino M, McKnight B, Medina-Gomez C, Monda KL, Montasser ME, Müller G, Müller-Nurasyid M, Nolte IM, Panoutsopoulou K, Pascoe L, Paternoster L, Rayner NW, Renström F, Rizzi F, Rose LM, Ryan KA, Salo P, Sanna S, Scharnagl H, Shi J, Smith AV, Southam L, Stancáková A, Steinthorsdottir V, Strawbridge RJ, Sung YJ, Tachmazidou I, Tanaka T, Thorleifsson G, Trompet S, Pervjakova N, Tyrer JP, Vandenput L, van der Laan SW, van der Velde N, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Vlachopoulou E, Waite LL, Wang SR, Wang Z, Wild SH, Willenborg C, Wilson JF, Wong A, Yang J, Yengo L, Yerges-Armstrong LM, Yu L, Zhang W, Zhao JH, Andersson EA, Bakker SJ, Baldassarre D, Banasik K, Barcella M, Barlassina C, Bellis C, Benaglio P, Blangero J, Blüher M, Bonnet F, Bonnycastle LL, Boyd HA, Bruinenberg M, Buchman AS, Campbell H, Chen YI, Chines PS, Claudi-Boehm S, Cole J, Collins FS, de Geus EJ, de Groot LC, Dimitriou M, Duan J, Enroth S, Eury E, Farmaki AE, Forouhi NG, Friedrich N, Gejman PV, Gigante B, Glorioso N, Go AS, Gottesman O, Gräßler J, Grallert H, Grarup N, Gu YM, Broer L, Ham AC, Hansen T, Harris TB, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Heath AC, Henders AK, Hernandez D, Hillege H, Holmen O, Hovingh KG, Hui J, Husemoen LL, Hutri-Kähönen N, Hysi PG, Illig T, De Jager PL, Jalilzadeh S, Jørgensen T, Jukema JW, Juonala M, Kanoni S, Karaleftheri M, Khaw KT, Kinnunen L, Kittner SJ, Koenig W, Kolcic I, Kovacs P, Krarup NT, Kratzer W, Krüger J, Kuh D, Kumari M, Kyriakou T, Langenberg C, Lannfelt L, Lanzani C, Lotay V, Launer LJ, Leander K, Lindström J, Linneberg A, Liu YP, Lobbens S, Luben R, Lyssenko V, Männistö S, Magnusson PK, McArdle WL, Menni C, Merger S, Milani L, Montgomery GW, Morris AP, Narisu N, Nelis M, Ong KK, Palotie A, Pérusse L, Pichler I, Pilia MG, Pouta A, Rheinberger M, Ribel-Madsen R, Richards M, Rice KM, Rice TK, Rivolta C, Salomaa V, Sanders AR, Sarzynski MA, Scholtens S, Scott RA, Scott WR, Sebert S, Sengupta S, Sennblad B, Seufferlein T, Silveira A, Slagboom PE, Smit JH, Sparsø TH, Stirrups K, Stolk RP, Stringham HM, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Thorand B, Tönjes A, Tremblay A, Tsafantakis E, van der Most PJ, Völker U, Vohl MC, Vonk JM, Waldenberger M, Walker RW, Wennauer R, Widén E, Willemsen G, Wilsgaard T, Wright AF, Zillikens MC, van Dijk SC, van Schoor NM, Asselbergs FW, de Bakker PI, Beckmann JS, Beilby J, Bennett DA, Bergman RN, Bergmann S, Böger CA, Boehm BO, Boerwinkle E, Boomsma DI, Bornstein SR, Bottinger EP, Bouchard C, Chambers JC, Chanock SJ, Chasman DI, Cucca F, Cusi D, Dedoussis G, Erdmann J, Eriksson JG, Evans DA, de Faire U, Farrall M, Ferrucci L, Ford I, Franke L, Franks PW, Froguel P, Gansevoort RT, Gieger C, Grönberg H, Gudnason V, Gyllensten U, Hall P, Hamsten A, van der Harst P, Hayward C, Heliövaara M, Hengstenberg C, Hicks AA, Hingorani A, Hofman A, Hu F, Huikuri HV, Hveem K, James AL, Jordan JM, Jula A, Kähönen M, Kajantie E, Kathiresan S, Kiemeney LA, Kivimaki M, Knekt PB, Koistinen HA, Kooner JS, Koskinen S, Kuusisto J, Maerz W, Martin NG, Laakso M, Lakka TA, Lehtimäki T, Lettre G, Levinson DF, Lind L, Lokki ML, Mäntyselkä P, Melbye M, Metspalu A, et al. Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genet. 2016 Jun; 12(6):e1006166. PMID: 27355579.
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  181. Janki S, Steyerberg EW, Hofman A, IJzermans JN. Live kidney donation: are concerns about long-term safety justified?-A methodological review. Eur J Epidemiol. 2017 Feb; 32(2):103-111. PMID: 27352382.
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  182. Dekkers KF, van Iterson M, Slieker RC, Moed MH, Bonder MJ, van Galen M, Mei H, Zhernakova DV, van den Berg LH, Deelen J, van Dongen J, van Heemst D, Hofman A, Hottenga JJ, van der Kallen CJ, Schalkwijk CG, Stehouwer CD, Tigchelaar EF, Uitterlinden AG, Willemsen G, Zhernakova A, Franke L, 't Hoen PA, Jansen R, van Meurs J, Boomsma DI, van Duijn CM, van Greevenbroek MM, Veldink JH, Wijmenga C, van Zwet EW, Slagboom PE, Jukema JW, Heijmans BT. Blood lipids influence DNA methylation in circulating cells. Genome Biol. 2016 Jun 27; 17(1):138. PMID: 27350042; PMCID: PMC4922056.
  183. Tajuddin SM, Schick UM, Eicher JD, Chami N, Giri A, Brody JA, Hill WD, Kacprowski T, Li J, Lyytikäinen LP, Manichaikul A, Mihailov E, O'Donoghue ML, Pankratz N, Pazoki R, Polfus LM, Smith AV, Schurmann C, Vacchi-Suzzi C, Waterworth DM, Evangelou E, Yanek LR, Burt A, Chen MH, van Rooij FJ, Floyd JS, Greinacher A, Harris TB, Highland HM, Lange LA, Liu Y, Mägi R, Nalls MA, Mathias RA, Nickerson DA, Nikus K, Starr JM, Tardif JC, Tzoulaki I, Velez Edwards DR, Wallentin L, Bartz TM, Becker LC, Denny JC, Raffield LM, Rioux JD, Friedrich N, Fornage M, Gao H, Hirschhorn JN, Liewald DC, Rich SS, Uitterlinden A, Bastarache L, Becker DM, Boerwinkle E, de Denus S, Bottinger EP, Hayward C, Hofman A, Homuth G, Lange E, Launer LJ, Lehtimäki T, Lu Y, Metspalu A, O'Donnell CJ, Quarells RC, Richard M, Torstenson ES, Taylor KD, Vergnaud AC, Zonderman AB, Crosslin DR, Deary IJ, Dörr M, Elliott P, Evans MK, Gudnason V, Kähönen M, Psaty BM, Rotter JI, Slater AJ, Dehghan A, White HD, Ganesh SK, Loos RJ, Esko T, Faraday N, Wilson JG, Cushman M, Johnson AD, Edwards TL, Zakai NA, Lettre G, Reiner AP, Auer PL. Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. Am J Hum Genet. 2016 Jul 07; 99(1):22-39. PMID: 27346689; PMCID: PMC5005433 [Available on 01/07/17].
  184. Mutlu U, Ikram MA, Hofman A, de Jong PT, Klaver CC, Ikram MK. N-Terminal Pro-B-Type Natriuretic Peptide Is Related to Retinal Microvascular Damage: The Rotterdam Study. Arterioscler Thromb Vasc Biol. 2016 Aug; 36(8):1698-702. PMID: 27339461.
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  185. Chami N, Chen MH, Slater AJ, Eicher JD, Evangelou E, Tajuddin SM, Love-Gregory L, Kacprowski T, Schick UM, Nomura A, Giri A, Lessard S, Brody JA, Schurmann C, Pankratz N, Yanek LR, Manichaikul A, Pazoki R, Mihailov E, Hill WD, Raffield LM, Burt A, Bartz TM, Becker DM, Becker LC, Boerwinkle E, Bork-Jensen J, Bottinger EP, O'Donoghue ML, Crosslin DR, de Denus S, Dubé MP, Elliott P, Engström G, Evans MK, Floyd JS, Fornage M, Gao H, Greinacher A, Gudnason V, Hansen T, Harris TB, Hayward C, Hernesniemi J, Highland HM, Hirschhorn JN, Hofman A, Irvin MR, Kähönen M, Lange E, Launer LJ, Lehtimäki T, Li J, Liewald DC, Linneberg A, Liu Y, Lu Y, Lyytikäinen LP, Mägi R, Mathias RA, Melander O, Metspalu A, Mononen N, Nalls MA, Nickerson DA, Nikus K, O'Donnell CJ, Orho-Melander M, Pedersen O, Petersmann A, Polfus L, Psaty BM, Raitakari OT, Raitoharju E, Richard M, Rice KM, Rivadeneira F, Rotter JI, Schmidt F, Smith AV, Starr JM, Taylor KD, Teumer A, Thuesen BH, Torstenson ES, Tracy RP, Tzoulaki I, Zakai NA, Vacchi-Suzzi C, van Duijn CM, van Rooij FJ, Cushman M, Deary IJ, Velez Edwards DR, Vergnaud AC, Wallentin L, Waterworth DM, White HD, Wilson JG, Zonderman AB, Kathiresan S, Grarup N, Esko T, Loos RJ, Lange LA, Faraday N, Abumrad NA, Edwards TL, Ganesh SK, Auer PL, Johnson AD, Reiner AP, Lettre G. Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. Am J Hum Genet. 2016 Jul 07; 99(1):8-21. PMID: 27346685; PMCID: PMC5005438 [Available on 01/07/17].
  186. Bos D, Poels MM, Adams HH, Akoudad S, Cremers LG, Zonneveld HI, Hoogendam YY, Verhaaren BF, Verlinden VJ, Verbruggen JG, Peymani A, Hofman A, Krestin GP, Vincent AJ, Feelders RA, Koudstaal PJ, van der Lugt A, Ikram MA, Vernooij MW. Prevalence, Clinical Management, and Natural Course of Incidental Findings on Brain MR Images: The Population-based Rotterdam Scan Study. Radiology. 2016 Nov; 281(2):507-515. PMID: 27337027.
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  187. Ghanbari M, Ikram MA, de Looper HW, Hofman A, Erkeland SJ, Franco OH, Dehghan A. Genome-wide identification of microRNA-related variants associated with risk of Alzheimer's disease. Sci Rep. 2016 Jun 22; 6:28387. PMID: 27328823; PMCID: PMC4916596.
  188. Matteini AM, Tanaka T, Karasik D, Atzmon G, Chou WC, Eicher JD, Johnson AD, Arnold AM, Callisaya ML, Davies G, Evans DS, Holtfreter B, Lohman K, Lunetta KL, Mangino M, Smith AV, Smith JA, Teumer A, Yu L, Arking DE, Buchman AS, Chibinik LB, De Jager PL, Evans DA, Faul JD, Garcia ME, Gillham-Nasenya I, Gudnason V, Hofman A, Hsu YH, Ittermann T, Lahousse L, Liewald DC, Liu Y, Lopez L, Rivadeneira F, Rotter JI, Siggeirsdottir K, Starr JM, Thomson R, Tranah GJ, Uitterlinden AG, Völker U, Völzke H, Weir DR, Yaffe K, Zhao W, Zhuang WV, Zmuda JM, Bennett DA, Cummings SR, Deary IJ, Ferrucci L, Harris TB, Kardia SL, Kocher T, Kritchevsky SB, Psaty BM, Seshadri S, Spector TD, Srikanth VK, Windham BG, Zillikens MC, Newman AB, Walston JD, Kiel DP, Murabito JM. GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium. Aging Cell. 2016 Oct; 15(5):792-800. PMID: 27325353.
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  189. Teumer A, Qi Q, Nethander M, Aschard H, Bandinelli S, Beekman M, Berndt SI, Bidlingmaier M, Broer L, Cappola A, Ceda GP, Chanock S, Chen MH, Chen TC, Chen YD, Chung J, Del Greco Miglianico F, Eriksson J, Ferrucci L, Friedrich N, Gnewuch C, Goodarzi MO, Grarup N, Guo T, Hammer E, Hayes RB, Hicks AA, Hofman A, Houwing-Duistermaat JJ, Hu F, Hunter DJ, Husemoen LL, Isaacs A, Jacobs KB, Janssen JA, Jansson JO, Jehmlich N, Johnson S, Juul A, Karlsson M, Kilpelainen TO, Kovacs P, Kraft P, Li C, Linneberg A, Liu Y, Loos RJ, Lorentzon M, Lu Y, Maggio M, Magi R, Meigs J, Mellström D, Nauck M, Newman AB, Pollak MN, Pramstaller PP, Prokopenko I, Psaty BM, Reincke M, Rimm EB, Rotter JI, Saint Pierre A, Schurmann C, Seshadri S, Sjögren K, Slagboom PE, Strickler HD, Stumvoll M, Suh Y, Sun Q, Zhang C, Svensson J, Tanaka T, Tare A, Tönjes A, Uh HW, van Duijn CM, van Heemst D, Vandenput L, Vasan RS, Völker U, Willems SM, Ohlsson C, Wallaschofski H, Kaplan RC. Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits. Aging Cell. 2016 Oct; 15(5):811-24. PMID: 27329260.
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  190. Gormley P, Anttila V, Winsvold BS, Palta P, Esko T, Pers TH, Farh KH, Cuenca-Leon E, Muona M, Furlotte NA, Kurth T, Ingason A, McMahon G, Ligthart L, Terwindt GM, Kallela M, Freilinger TM, Ran C, Gordon SG, Stam AH, Steinberg S, Borck G, Koiranen M, Quaye L, Adams HH, Lehtimäki T, Sarin AP, Wedenoja J, Hinds DA, Buring JE, Schürks M, Ridker PM, Hrafnsdottir MG, Stefansson H, Ring SM, Hottenga JJ, Penninx BW, Färkkilä M, Artto V, Kaunisto M, Vepsäläinen S, Malik R, Heath AC, Madden PA, Martin NG, Montgomery GW, Kurki MI, Kals M, Mägi R, Pärn K, Hämäläinen E, Huang H, Byrnes AE, Franke L, Huang J, Stergiakouli E, Lee PH, Sandor C, Webber C, Cader Z, Muller-Myhsok B, Schreiber S, Meitinger T, Eriksson JG, Salomaa V, Heikkilä K, Loehrer E, Uitterlinden AG, Hofman A, van Duijn CM, Cherkas L, Pedersen LM, Stubhaug A, Nielsen CS, Männikkö M, Mihailov E, Milani L, Göbel H, Esserlind AL, Christensen AF, Hansen TF, Werge T, Kaprio J, Aromaa AJ, Raitakari O, Ikram MA, Spector T, Järvelin MR, Metspalu A, Kubisch C, Strachan DP, Ferrari MD, Belin AC, Dichgans M, Wessman M, van den Maagdenberg AM, Zwart JA, Boomsma DI, Smith GD, Stefansson K, Eriksson N, Daly MJ, Neale BM, Olesen J, Chasman DI, Nyholt DR, Palotie A. Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. Nat Genet. 2016 Aug; 48(8):856-66. PMID: 27322543.
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  191. Ligthart S, Vaez A, Hsu YH, Stolk R, Uitterlinden AG, Hofman A, Alizadeh BZ, Franco OH, Dehghan A. Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation. BMC Genomics. 2016 Jun 10; 17:443. PMID: 27286809; PMCID: PMC4901478.
  192. Bano A, Chaker L, Plompen EP, Hofman A, Dehghan A, Franco OH, Janssen HL, Darwish Murad S, Peeters RP. Thyroid Function and the Risk of Nonalcoholic Fatty Liver Disease: The Rotterdam Study. J Clin Endocrinol Metab. 2016 Aug; 101(8):3204-11. PMID: 27270473.
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  193. Portegies ML, Mirza SS, Verlinden VJ, Hofman A, Koudstaal PJ, Swanson SA, Ikram MA. Mid- to Late-Life Trajectories of Blood Pressure and the Risk of Stroke: The Rotterdam Study. Hypertension. 2016 Jun; 67(6):1126-32. PMID: 27160196.
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  194. Darweesh SK, Verlinden VJ, Adams HH, Uitterlinden AG, Hofman A, Stricker BH, van Duijn CM, Koudstaal PJ, Ikram MA. Genetic risk of Parkinson's disease in the general population. Parkinsonism Relat Disord. 2016 Aug; 29:54-9. PMID: 27269966.
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  195. Zubakov D, Liu F, Kokmeijer I, Choi Y, van Meurs JB, van IJcken WF, Uitterlinden AG, Hofman A, Broer L, van Duijn CM, Lewin J, Kayser M. Human age estimation from blood using mRNA, DNA methylation, DNA rearrangement, and telomere length. Forensic Sci Int Genet. 2016 Sep; 24:33-43. PMID: 27288716.
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  196. Chen LY, Leening MJ, Norby FL, Roetker NS, Hofman A, Franco OH, Pan W, Polak JF, Witteman JC, Kronmal RA, Folsom AR, Nazarian S, Stricker BH, Heckbert SR, Alonso A. Carotid Intima-Media Thickness and Arterial Stiffness and the Risk of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study, Multi-Ethnic Study of Atherosclerosis (MESA), and the Rotterdam Study. J Am Heart Assoc. 2016 May 20; 5(5). PMID: 27207996; PMCID: PMC4889172.
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  201. Direk N, Perez HS, Akoudad S, Verhaaren BF, Niessen WJ, Hofman A, Vernooij MW, Ikram MA, Tiemeier H. Markers of cerebral small vessel disease and severity of depression in the general population. Psychiatry Res. 2016 Jul 30; 253:1-6. PMID: 27254084.
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  207. Mirza SS, Wolters FJ, Swanson SA, Koudstaal PJ, Hofman A, Tiemeier H, Ikram MA. 10-year trajectories of depressive symptoms and risk of dementia: a population-based study. Lancet Psychiatry. 2016 Jul; 3(7):628-35. PMID: 27138970.
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  208. Darweesh SK, Koudstaal PJ, Stricker BH, Hofman A, Ikram MA. Trends in the Incidence of Parkinson Disease in the General Population: The Rotterdam Study. Am J Epidemiol. 2016 Jun 01; 183(11):1018-26. PMID: 27188952.
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  209. Liu F, Hamer MA, Deelen J, Lall JS, Jacobs L, van Heemst D, Murray PG, Wollstein A, de Craen AJ, Uh HW, Zeng C, Hofman A, Uitterlinden AG, Houwing-Duistermaat JJ, Pardo LM, Beekman M, Slagboom PE, Nijsten T, Kayser M, Gunn DA. The MC1R Gene and Youthful Looks. Curr Biol. 2016 May 09; 26(9):1213-20. PMID: 27133870.
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  227. Norby FL, Eryd SA, Niemeijer MN, Rose LM, Smith AV, Yin X, Agarwal SK, Arking DE, Chasman DL, Chen LY, Eijgelsheim M, Engström G, Franco OH, Heeringa J, Hindy G, Hofman A, Lutsey PL, Magnani JW, McManus DD, Orho-Melander M, Pankow JS, Rukh G, Schulz CA, Uitterlinden AG, Albert CM, Benjamin EJ, Gudnason V, Smith JG, Stricker BH, Alonso A. Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium. PLoS One. 2016; 11(3):e0151932. PMID: 26999784; PMCID: PMC4801208.
  228. Lal D, Reinthaler EM, Dejanovic B, May P, Thiele H, Lehesjoki AE, Schwarz G, Riesch E, Ikram MA, van Duijn CM, Uitterlinden AG, Hofman A, Steinböck H, Gruber-Sedlmayr U, Neophytou B, Zara F, Hahn A, Gormley P, Becker F, Weber YG, Cilio MR, Kunz WS, Krause R, Zimprich F, Lemke JR, Nürnberg P, Sander T, Lerche H, Neubauer BA. Evaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes. PLoS One. 2016; 11(3):e0150426. PMID: 26990884; PMCID: PMC4798642.
  229. Mous SE, Schoemaker NK, Blanken LM, Thijssen S, van der Ende J, Polderman TJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, White T. The association of gender, age, and intelligence with neuropsychological functioning in young typically developing children: The Generation R study. Appl Neuropsychol Child. 2017 Jan-Mar; 6(1):22-40. PMID: 26986060.
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  230. Tyrrell J, Richmond RC, Palmer TM, Feenstra B, Rangarajan J, Metrustry S, Cavadino A, Paternoster L, Armstrong LL, De Silva NM, Wood AR, Horikoshi M, Geller F, Myhre R, Bradfield JP, Kreiner-Møller E, Huikari V, Painter JN, Hottenga JJ, Allard C, Berry DJ, Bouchard L, Das S, Evans DM, Hakonarson H, Hayes MG, Heikkinen J, Hofman A, Knight B, Lind PA, McCarthy MI, McMahon G, Medland SE, Melbye M, Morris AP, Nodzenski M, Reichetzeder C, Ring SM, Sebert S, Sengpiel V, Sørensen TI, Willemsen G, de Geus EJ, Martin NG, Spector TD, Power C, Järvelin MR, Bisgaard H, Grant SF, Nohr EA, Jaddoe VW, Jacobsson B, Murray JC, Hocher B, Hattersley AT, Scholtens DM, Davey Smith G, Hivert MF, Felix JF, Hyppönen E, Lowe WL, Frayling TM, Lawlor DA, Freathy RM. Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight. JAMA. 2016 Mar 15; 315(11):1129-40. PMID: 26978208; PMCID: PMC4811305.
  231. Mutlu U, Adams HH, Hofman A, Lugt Av, Klaver CC, Vernooij MW, Ikram MK, Ikram MA. Retinal Microvascular Calibers Are Associated With Enlarged Perivascular Spaces in the Brain. Stroke. 2016 May; 47(5):1374-6. PMID: 26979867.
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  232. Parmar PG, Taal HR, Timpson NJ, Thiering E, Lehtimäki T, Marinelli M, Lind PA, Howe LD, Verwoert G, Aalto V, Uitterlinden AG, Briollais L, Evans DM, Wright MJ, Newnham JP, Whitfield JB, Lyytikäinen LP, Rivadeneira F, Boomsma DI, Viikari J, Gillman MW, St Pourcain B, Hottenga JJ, Montgomery GW, Hofman A, Kähönen M, Martin NG, Tobin MD, Raitakari O, Vioque J, Jaddoe VWV, Jarvelin MR, Beilin LJ, Heinrich J, van Duijn CM, Pennell CE, Lawlor DA, Palmer LJ. International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents. Circ Cardiovasc Genet. 2016 Jun; 9(3):266-278. PMID: 26969751.
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  233. Adams HH, Ikram MA, Vernooij MW, van Dijk AC, Hofman A, Uitterlinden AG, van Duijn CM, Koudstaal PJ, Franco OH, van der Lugt A, Bos D. Heritability and Genome-Wide Association Analyses of Intracranial Carotid Artery Calcification: The Rotterdam Study. Stroke. 2016 Apr; 47(4):912-7. PMID: 26965845.
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  234. Hassing RJ, Verbon A, de Visser H, Hofman A, Stricker BH. Proton pump inhibitors and gastroenteritis. Eur J Epidemiol. 2016 Oct; 31(10):1057-1063. PMID: 26960438.
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  235. Miliku K, Vogelezang S, Franco OH, Hofman A, Jaddoe VW, Felix JF. Influence of common genetic variants on childhood kidney outcomes. Pediatr Res. 2016 07; 80(1):60-6. PMID: 26959481.
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  236. Dhana K, van Rosmalen J, Vistisen D, Ikram MA, Hofman A, Franco OH, Kavousi M. Trajectories of body mass index before the diagnosis of cardiovascular disease: a latent class trajectory analysis. Eur J Epidemiol. 2016 Jun; 31(6):583-92. PMID: 26955830; PMCID: PMC4956703.
  237. Tideman JW, Polling JR, Voortman T, Jaddoe VW, Uitterlinden AG, Hofman A, Vingerling JR, Franco OH, Klaver CC. Low serum vitamin D is associated with axial length and risk of myopia in young children. Eur J Epidemiol. 2016 May; 31(5):491-9. PMID: 26955828; PMCID: PMC4901111.
  238. Dehghan A, Bis JC, White CC, Smith AV, Morrison AC, Cupples LA, Trompet S, Chasman DI, Lumley T, Völker U, Buckley BM, Ding J, Jensen MK, Folsom AR, Kritchevsky SB, Girman CJ, Ford I, Dörr M, Salomaa V, Uitterlinden AG, Eiriksdottir G, Vasan RS, Franceschini N, Carty CL, Virtamo J, Demissie S, Amouyel P, Arveiler D, Heckbert SR, Ferrières J, Ducimetière P, Smith NL, Wang YA, Siscovick DS, Rice KM, Wiklund PG, Taylor KD, Evans A, Kee F, Rotter JI, Karvanen J, Kuulasmaa K, Heiss G, Kraft P, Launer LJ, Hofman A, Markus MR, Rose LM, Silander K, Wagner P, Benjamin EJ, Lohman K, Stott DJ, Rivadeneira F, Harris TB, Levy D, Liu Y, Rimm EB, Jukema JW, Völzke H, Ridker PM, Blankenberg S, Franco OH, Gudnason V, Psaty BM, Boerwinkle E, O'Donnell CJ. Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium. PLoS One. 2016; 11(3):e0144997. PMID: 26950853; PMCID: PMC4780701.
  239. Terzikhan N, Verhamme KM, Hofman A, Stricker BH, Brusselle GG, Lahousse L. Prevalence and incidence of COPD in smokers and non-smokers: the Rotterdam Study. Eur J Epidemiol. 2016 Aug; 31(8):785-92. PMID: 26946425; PMCID: PMC5005388.
  240. Muka T, Kraja B, Ruiter R, de Keyser CE, Hofman A, Stricker BH, Kiefte-de Jong JC, Franco OH. Dietary polyunsaturated fatty acids intake modifies the positive association between serum total cholesterol and colorectal cancer risk: the Rotterdam Study. J Epidemiol Community Health. 2016 Sep; 70(9):881-7. PMID: 26917548.
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  241. Vidakovic AJ, Gishti O, Voortman T, Felix JF, Williams MA, Hofman A, Demmelmair H, Koletzko B, Tiemeier H, Jaddoe VW, Gaillard R. Maternal plasma PUFA concentrations during pregnancy and childhood adiposity: the Generation R Study. Am J Clin Nutr. 2016 Apr; 103(4):1017-25. PMID: 26912493.
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  242. Darweesh SK, Koudstaal PJ, Stricker BH, Hofman A, Steyerberg EW, Ikram MA. Predicting Parkinson disease in the community using a nonmotor risk score. Eur J Epidemiol. 2016 Jul; 31(7):679-84. PMID: 26898908; PMCID: PMC4977330.
  243. Ricaño-Ponce I, Zhernakova DV, Deelen P, Luo O, Li X, Isaacs A, Karjalainen J, Di Tommaso J, Borek ZA, Zorro MM, Gutierrez-Achury J, Uitterlinden AG, Hofman A, van Meurs J, Netea MG, Jonkers IH, Withoff S, van Duijn CM, Li Y, Ruan Y, Franke L, Wijmenga C, Kumar V. Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs. J Autoimmun. 2016 Apr; 68:62-74. PMID: 26898941.
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  244. Portegies ML, Bos MJ, Koudstaal PJ, Hofman A, Tiemeier HW, Ikram MA. Anxiety and the Risk of Stroke: The Rotterdam Study. Stroke. 2016 Apr; 47(4):1120-3. PMID: 26883500.
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  245. Wijtzes AI, Jansen W, Bouthoorn SH, Kiefte-de Jong JC, Jansen PW, Franco OH, Jaddoe VW, Hofman A, Raat H. PROP taster status, food preferences and consumption of high-calorie snacks and sweet beverages among 6-year-old ethnically diverse children. Matern Child Nutr. 2017 Apr; 13(2). PMID: 26878993.
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  246. Wolters FJ, Koudstaal PJ, Hofman A, van Duijn CM, Ikram MA. Serum apolipoprotein E is associated with long-term risk of Alzheimer's disease: The Rotterdam Study. Neurosci Lett. 2016 Mar 23; 617:139-42. PMID: 26876448.
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  247. Cibis M, Potters WV, Selwaness M, Gijsen FJ, Franco OH, Arias Lorza AM, de Bruijne M, Hofman A, van der Lugt A, Nederveen AJ, Wentzel JJ. Relation between wall shear stress and carotid artery wall thickening MRI versus CFD. J Biomech. 2016 Mar 21; 49(5):735-41. PMID: 26897648.
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  248. Joubert BR, den Dekker HT, Felix JF, Bohlin J, Ligthart S, Beckett E, Tiemeier H, van Meurs JB, Uitterlinden AG, Hofman A, Håberg SE, Reese SE, Peters MJ, Andreassen BK, Steegers EA, Nilsen RM, Vollset SE, Midttun Ø, Ueland PM, Franco OH, Dehghan A, de Jongste JC, Wu MC, Wang T, Peddada SD, Jaddoe VW, Nystad W, Duijts L, London SJ. Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns. Nat Commun. 2016 Feb 10; 7:10577. PMID: 26861414; PMCID: PMC4749955.
  249. van den Hooven EH, Gharsalli M, Heppe DH, Raat H, Hofman A, Franco OH, Rivadeneira F, Jaddoe VW. Associations of breast-feeding patterns and introduction of solid foods with childhood bone mass: The Generation R Study. Br J Nutr. 2016 Mar 28; 115(6):1024-32. PMID: 26856234.
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  250. Dashti HS, Zuurbier LA, de Jonge E, Voortman T, Jacques PF, Lamon-Fava S, Scheer FA, Kiefte-De Jong JC, Hofman A, Ordovás JM, Franco OH, Tiemeier H. Actigraphic sleep fragmentation, efficiency and duration associate with dietary intake in the Rotterdam Study. J Sleep Res. 2016 Aug; 25(4):404-11. PMID: 26857552; PMCID: PMC4980236 [Available on 08/01/17].
  251. Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Del Greco M F, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley BM, Böhringer S, I Chen YD, de Craen AJ, Crosslin DR, Dale CE, Dastani Z, Day FR, Deelen J, Delgado GE, Demirkan A, Finucane FM, Ford I, Garcia ME, Gieger C, Gustafsson S, Hallmans G, Hankinson SE, Havulinna AS, Herder C, Hernandez D, Hicks AA, Hunter DJ, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson JO, Jenny NS, Jørgensen ME, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig KH, LeDuc CA, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris AP, Myers RH, Männistö S, Nalls MA, Paternoster L, Peters A, Pradhan AD, Rankinen T, Rasmussen-Torvik LJ, Rathmann W, Rice TK, Brent Richards J, Ridker PM, Sattar N, Savage DB, Söderberg S, Timpson NJ, Vandenput L, van Heemst D, Uh HW, Vohl MC, Walker M, Wichmann HE, Widén E, Wood AR, Yao J, Zeller T, Zhang Y, Meulenbelt I, Kloppenburg M, Astrup A, Sørensen TI, Sarzynski MA, Rao DC, Jousilahti P, Vartiainen E, Hofman A, Rivadeneira F, Uitterlinden AG, Kajantie E, Osmond C, Palotie A, Eriksson JG, Heliövaara M, Knekt PB, Koskinen S, Jula A, Perola M, Huupponen RK, Viikari JS, Kähönen M, Lehtimäki T, Raitakari OT, Mellström D, Lorentzon M, Casas JP, Bandinelli S, März W, Isaacs A, van Dijk KW, van Duijn CM, Harris TB, Bouchard C, Allison MA, Chasman DI, Ohlsson C, Lind L, Scott RA, Langenberg C, Wareham NJ, Ferrucci L, Frayling TM, Pramstaller PP, Borecki IB, Waterworth DM, Bergmann S, Waeber G, Vollenweider P, Vestergaard H, Hansen T, Pedersen O, Hu FB, Eline Slagboom P, Grallert H, Spector TD, Jukema JW, Klein RJ, Schadt EE, Franks PW, Lindgren CM, Leibel RL, Loos RJ. Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nat Commun. 2016 Feb 01; 7:10494. PMID: 26833098; PMCID: PMC4740377.
  252. Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman ÅK, Haring R, Hysi PG, Iles MM, Justice AE, Kanoni S, Lagou V, Li R, Li X, Locke A, Lu C, Mägi R, Perry JR, Pers TH, Qi Q, Sanna M, Schmidt EM, Scott WR, Shungin D, Teumer A, Vinkhuyzen AA, Walker RW, Westra HJ, Zhang M, Zhang W, Zhao JH, Zhu Z, Afzal U, Ahluwalia TS, Bakker SJ, Bellis C, Bonnefond A, Borodulin K, Buchman AS, Cederholm T, Choh AC, Choi HJ, Curran JE, de Groot LC, De Jager PL, Dhonukshe-Rutten RA, Enneman AW, Eury E, Evans DS, Forsen T, Friedrich N, Fumeron F, Garcia ME, Gärtner S, Han BG, Havulinna AS, Hayward C, Hernandez D, Hillege H, Ittermann T, Kent JW, Kolcic I, Laatikainen T, Lahti J, Mateo Leach I, Lee CG, Lee JY, Liu T, Liu Y, Lobbens S, Loh M, Lyytikäinen LP, Medina-Gomez C, Michaëlsson K, Nalls MA, Nielson CM, Oozageer L, Pascoe L, Paternoster L, Polašek O, Ripatti S, Sarzynski MA, Shin CS, Narancic NS, Spira D, Srikanth P, Steinhagen-Thiessen E, Sung YJ, Swart KM, Taittonen L, Tanaka T, Tikkanen E, van der Velde N, van Schoor NM, Verweij N, Wright AF, Yu L, Zmuda JM, Eklund N, Forrester T, Grarup N, Jackson AU, Kristiansson K, Kuulasmaa T, Kuusisto J, Lichtner P, Luan J, Mahajan A, Männistö S, Palmer CD, Ried JS, Scott RA, Stancáková A, Wagner PJ, Demirkan A, Döring A, Gudnason V, Kiel DP, Kühnel B, Mangino M, Mcknight B, Menni C, O'Connell JR, Oostra BA, Shuldiner AR, Song K, Vandenput L, van Duijn CM, Vollenweider P, White CC, Boehnke M, Boettcher Y, Cooper RS, Forouhi NG, Gieger C, Grallert H, Hingorani A, Jørgensen T, Jousilahti P, Kivimaki M, Kumari M, Laakso M, Langenberg C, Linneberg A, Luke A, Mckenzie CA, Palotie A, Pedersen O, Peters A, Strauch K, Tayo BO, Wareham NJ, Bennett DA, Bertram L, Blangero J, Blüher M, Bouchard C, Campbell H, Cho NH, Cummings SR, Czerwinski SA, Demuth I, Eckardt R, Eriksson JG, Ferrucci L, Franco OH, Froguel P, Gansevoort RT, Hansen T, Harris TB, Hastie N, Heliövaara M, Hofman A, Jordan JM, Jula A, Kähönen M, Kajantie E, Knekt PB, Koskinen S, Kovacs P, Lehtimäki T, Lind L, Liu Y, Orwoll ES, Osmond C, Perola M, Pérusse L, Raitakari OT, Rankinen T, Rao DC, Rice TK, Rivadeneira F, Rudan I, Salomaa V, Sørensen TI, Stumvoll M, Tönjes A, Towne B, Tranah GJ, Tremblay A, Uitterlinden AG, van der Harst P, Vartiainen E, Viikari JS, Vitart V, Vohl MC, Völzke H, Walker M, Wallaschofski H, Wild S, Wilson JF, Yengo L, Bishop DT, Borecki IB, Chambers JC, Cupples LA, Dehghan A, Deloukas P, Fatemifar G, Fox C, Furey TS, Franke L, Han J, Hunter DJ, Karjalainen J, Karpe F, Kaplan RC, Kooner JS, McCarthy MI, Murabito JM, Morris AP, Bishop JA, North KE, Ohlsson C, Ong KK, Prokopenko I, Richards JB, Schadt EE, Spector TD, Widén E, Willer CJ, Yang J, Ingelsson E, Mohlke KL, Hirschhorn JN, Pospisilik JA, Zillikens MC, Lindgren C, Kilpeläinen TO, Loos RJ. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Nat Commun. 2016 Feb 01; 7:10495. PMID: 26833246; PMCID: PMC4740398.
  253. Basten M, Tiemeier H, Althoff RR, van de Schoot R, Jaddoe VW, Hofman A, Hudziak JJ, Verhulst FC, van der Ende J. The Stability of Problem Behavior Across the Preschool Years: An Empirical Approach in the General Population. J Abnorm Child Psychol. 2016 Feb; 44(2):393-404. PMID: 25832625; PMCID: PMC4729812.
  254. Janki S, Klop KW, Kimenai HJ, van de Wetering J, Weimar W, Massey EK, Dehghan A, Rizopoulos D, Völzke H, Hofman A, Ijzermans JN. LOng-term follow-up after liVE kidney donation (LOVE) study: a longitudinal comparison study protocol. BMC Nephrol. 2016 Feb 01; 17:14. PMID: 26830198; PMCID: PMC4736233.
  255. van der Voort EA, Koehler EM, Nijsten T, Stricker BH, Hofman A, Janssen HL, Schouten JN, Wakkee M. Increased Prevalence of Advanced Liver Fibrosis in Patients with Psoriasis: A Cross-sectional Analysis from the Rotterdam Study. Acta Derm Venereol. 2016 Feb; 96(2):213-7. PMID: 26062958.
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  256. Portegies ML, Lahousse L, Joos GF, Hofman A, Koudstaal PJ, Stricker BH, Brusselle GG, Ikram MA. Chronic Obstructive Pulmonary Disease and the Risk of Stroke. The Rotterdam Study. Am J Respir Crit Care Med. 2016 Feb 01; 193(3):251-8. PMID: 26414484.
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  257. van den Akker EB, Pitts SJ, Deelen J, Moed MH, Potluri S, van Rooij J, Suchiman HE, Lakenberg N, de Dijcker WJ, Uitterlinden AG, Kraaij R, Hofman A, de Craen AJ, Houwing-Duistermaat JJ, van Ommen GJ, Cox DR, van Meurs JB, Beekman M, Reinders MJ, Slagboom PE. Uncompromised 10-year survival of oldest old carrying somatic mutations in DNMT3A and TET2. Blood. 2016 Mar 17; 127(11):1512-5. PMID: 26825711; PMCID: PMC4797027.
  258. Ligthart S, Steenaard RV, Peters MJ, van Meurs JB, Sijbrands EJ, Uitterlinden AG, Bonder MJ, Hofman A, Franco OH, Dehghan A. Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes. Diabetologia. 2016 May; 59(5):998-1006. PMID: 26825526; PMCID: PMC4826423.
  259. Peters MJ, Ramos YF, den Hollander W, Schiphof D, Hofman A, Uitterlinden AG, Oei EH, Slagboom PE, Kloppenburg M, Bloem JL, Bierma-Zeinstra SM, Meulenbelt I, van Meurs JB. Associations between joint effusion in the knee and gene expression levels in the circulation: a meta-analysis. F1000Res. 2016; 5:109. PMID: 27134727; PMCID: PMC4837985.
  260. Kieboom BC, Niemeijer MN, Leening MJ, van den Berg ME, Franco OH, Deckers JW, Hofman A, Zietse R, Stricker BH, Hoorn EJ. Serum Magnesium and the Risk of Death From Coronary Heart Disease and Sudden Cardiac Death. J Am Heart Assoc. 2016 Jan 22; 5(1). PMID: 26802105; PMCID: PMC4859391.
  261. Mirza SS, Portegies ML, Wolters FJ, Hofman A, Koudstaal PJ, Tiemeier H, Ikram MA. Higher Education Is Associated with a Lower Risk of Dementia after a Stroke or TIA. The Rotterdam Study. Neuroepidemiology. 2016; 46(2):120-7. PMID: 26794600.
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  262. Ars CL, Nijs IM, Marroun HE, Muetzel R, Schmidt M, Steenweg-de Graaff J, van der Lugt A, Jaddoe VW, Hofman A, Steegers EA, Verhulst FC, Tiemeier H, White T. Prenatal folate, homocysteine and vitamin B12 levels and child brain volumes, cognitive development and psychological functioning: the Generation R Study. Br J Nutr. 2016 Jan 22; 1-9. PMID: 26794411.
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  263. Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LP, Gambetti P, Blevins J, Zhang S, Cohen Y, Chen W, Yamada M, Hamaguchi T, Sanjo N, Mizusawa H, Nakamura Y, Kitamoto T, Collins SJ, Boyd A, Will RG, Knight R, Ponto C, Zerr I, Kraus TF, Eigenbrod S, Giese A, Calero M, de Pedro-Cuesta J, Haïk S, Laplanche JL, Bouaziz-Amar E, Brandel JP, Capellari S, Parchi P, Poleggi A, Ladogana A, O'Donnell-Luria AH, Karczewski KJ, Marshall JL, Boehnke M, Laakso M, Mohlke KL, Kähler A, Chambert K, McCarroll S, Sullivan PF, Hultman CM, Purcell SM, Sklar P, van der Lee SJ, Rozemuller A, Jansen C, Hofman A, Kraaij R, van Rooij JG, Ikram MA, Uitterlinden AG, van Duijn CM, Daly MJ, MacArthur DG. Quantifying prion disease penetrance using large population control cohorts. Sci Transl Med. 2016 Jan 20; 8(322):322ra9. PMID: 26791950; PMCID: PMC4774245.
  264. Akoudad S, Ikram MA, Portegies ML, Adams HH, Bos D, Hofman A, Koudstaal PJ, Uitterlinden AG, van der Lugt A, van Duijn CM, Vernooij MW. Genetic loci for serum lipid fractions and intracerebral hemorrhage. Atherosclerosis. 2016 Mar; 246:287-92. PMID: 26820804.
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  265. Liao X, Norata GD, Polak JF, Stehouwer CD, Catapano A, Rundek T, Ezhov M, Sander D, Thompson SG, Lorenz MW, Balakhonova T, Safarova M, Grigore L, Empana JP, Lin HJ, McLachlan S, Bokemark L, Ronkainen K, Schminke U, Lind L, Willeit P, Yanez DN, Steinmetz H, Poppert H, Desvarieux M, Ikram MA, Johnsen SH, Iglseder B, Friera A, Xie W, Plichart M, Su TC, Srinivasan SR, Schmidt C, Tuomainen TP, Völzke H, Nijpels G, Willeit J, Franco OH, Suarez C, Zhao D, Ducimetiere P, Chien KL, Robertson C, Bergström G, Kauhanen J, Dörr M, Dekker JM, Kiechl S, Sitzer M, Bickel H, Sacco RL, Hofman A, Mathiesen EB, Gabriel R, Liu J, Berenson G, Kavousi M, Price JF. Normative values for carotid intima media thickness and its progression: Are they transferrable outside of their cohort of origin? Eur J Prev Cardiol. 2016 Jul; 23(11):1165-73. PMID: 26746227.
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  266. Santos S, Gaillard R, Oliveira A, Barros H, Hofman A, Franco OH, Jaddoe VW. Subcutaneous fat mass in infancy and cardiovascular risk factors at school-age: The generation R study. Obesity (Silver Spring). 2016 Feb; 24(2):424-9. PMID: 26813529.
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  267. Ghanbari M, Darweesh SK, de Looper HW, van Luijn MM, Hofman A, Ikram MA, Franco OH, Erkeland SJ, Dehghan A. Genetic Variants in MicroRNAs and Their Binding Sites Are Associated with the Risk of Parkinson Disease. Hum Mutat. 2016 Mar; 37(3):292-300. PMID: 26670097.
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  268. Mileva-Seitz VR, Luijk MP, van Ijzendoorn MH, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. ASSOCIATION BETWEEN INFANT NIGHTTIME-SLEEP LOCATION AND ATTACHMENT SECURITY: NO EASY VERDICT. Infant Ment Health J. 2016 Jan-Feb; 37(1):5-16. PMID: 26719041.
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  269. Viana Veloso GG, Franco OH, Ruiter R, de Keyser CE, Hofman A, Stricker BC, Kiefte-de Jong JC. Baseline dietary glutamic acid intake and the risk of colorectal cancer: The Rotterdam study. Cancer. 2016 Mar 15; 122(6):899-907. PMID: 26717076.
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  270. Sonnenschein-van der Voort AM, Gaillard R, de Jongste JC, Hofman A, Jaddoe VW, Duijts L. Foetal and infant growth patterns, airway resistance and school-age asthma. Respirology. 2016 May; 21(4):674-82. PMID: 26699232.
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  271. Muka T, de Jonge EA, Kiefte-de Jong JC, Uitterlinden AG, Hofman A, Dehghan A, Zillikens MC, Franco OH, Rivadeneira F. The Influence of Serum Uric Acid on Bone Mineral Density, Hip Geometry, and Fracture Risk: The Rotterdam Study. J Clin Endocrinol Metab. 2016 Mar; 101(3):1113-22. PMID: 26684274.
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  273. Vidakovic AJ, Jaddoe VW, Gishti O, Felix JF, Williams MA, Hofman A, Demmelmair H, Koletzko B, Tiemeier H, Gaillard R. Body mass index, gestational weight gain and fatty acid concentrations during pregnancy: the Generation R Study. Eur J Epidemiol. 2015 Nov; 30(11):1175-85. PMID: 26666541; PMCID: PMC4684831.
  274. Yu B, Pulit SL, Hwang SJ, Brody JA, Amin N, Auer PL, Bis JC, Boerwinkle E, Burke GL, Chakravarti A, Correa A, Dreisbach AW, Franco OH, Ehret GB, Franceschini N, Hofman A, Lin DY, Metcalf GA, Musani SK, Muzny D, Palmas W, Raffel L, Reiner A, Rice K, Rotter JI, Veeraraghavan N, Fox E, Guo X, North KE, Gibbs RA, van Duijn CM, Psaty BM, Levy D, Newton-Cheh C, Morrison AC. Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk. Circ Cardiovasc Genet. 2016 Feb; 9(1):64-70. PMID: 26658788; PMCID: PMC4771070 [Available on 02/01/17].
  275. Akoudad S, Aarts N, Noordam R, Ikram MA, Tiemeier H, Hofman A, Stricker BH, Vernooij MW, Visser LE. Antidepressant Use Is Associated With an Increased Risk of Developing Microbleeds. Stroke. 2016 Jan; 47(1):251-4. PMID: 26658443.
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  276. Ikram MA, van der Lugt A, Niessen WJ, Koudstaal PJ, Krestin GP, Hofman A, Bos D, Vernooij MW. The Rotterdam Scan Study: design update 2016 and main findings. Eur J Epidemiol. 2015 Dec; 30(12):1299-315. PMID: 26650042; PMCID: PMC4690838.
  277. Koks N, Ghassabian A, Greaves-Lord K, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Maternal C-Reactive Protein Concentration in Early Pregnancy and Child Autistic Traits in the General Population. Paediatr Perinat Epidemiol. 2016 Mar; 30(2):181-9. PMID: 26860445; PMCID: PMC4751036 [Available on 03/01/17].
  278. Cremers LG, de Groot M, Hofman A, Krestin GP, van der Lugt A, Niessen WJ, Vernooij MW, Ikram MA. Altered tract-specific white matter microstructure is related to poorer cognitive performance: The Rotterdam Study. Neurobiol Aging. 2016 Mar; 39:108-17. PMID: 26923407.
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  279. Bos D, Leening MJ, Kavousi M, Hofman A, Franco OH, van der Lugt A, Vernooij MW, Ikram MA. Comparison of Atherosclerotic Calcification in Major Vessel Beds on the Risk of All-Cause and Cause-Specific Mortality: The Rotterdam Study. Circ Cardiovasc Imaging. 2015 Dec; 8(12). PMID: 26659376.
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  280. Ringoot AP, van der Ende J, Jansen PW, Measelle JR, Basten M, So P, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Why Mothers and Young Children Agree or Disagree in Their Reports of the Child's Problem Behavior. Child Psychiatry Hum Dev. 2015 Dec; 46(6):913-27. PMID: 25577034.
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  281. Mutlu U, Ikram MK, Wolters FJ, Hofman A, Klaver CC, Ikram MA. Retinal Microvasculature Is Associated With Long-Term Survival in the General Adult Dutch Population. Hypertension. 2016 Feb; 67(2):281-7. PMID: 26628677.
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  282. Portegies ML, Bos MJ, Hofman A, Heeringa J, Franco OH, Koudstaal PJ, Ikram MA. Role of Prestroke Vascular Pathology in Long-Term Prognosis After Stroke: The Rotterdam Study. Stroke. 2016 Jan; 47(1):80-7. PMID: 26604254.
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  283. Felix JF, Bradfield JP, Monnereau C, van der Valk RJ, Stergiakouli E, Chesi A, Gaillard R, Feenstra B, Thiering E, Kreiner-Møller E, Mahajan A, Pitkänen N, Joro R, Cavadino A, Huikari V, Franks S, Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimäki T, Curtin JA, Vioque J, Ahluwalia TS, Myhre R, Price TS, Vilor-Tejedor N, Yengo L, Grarup N, Ntalla I, Ang W, Atalay M, Bisgaard H, Blakemore AI, Bonnefond A, Carstensen L, Eriksson J, Flexeder C, Franke L, Geller F, Geserick M, Hartikainen AL, Haworth CM, Hirschhorn JN, Hofman A, Holm JC, Horikoshi M, Hottenga JJ, Huang J, Kadarmideen HN, Kähönen M, Kiess W, Lakka HM, Lakka TA, Lewin AM, Liang L, Lyytikäinen LP, Ma B, Magnus P, McCormack SE, McMahon G, Mentch FD, Middeldorp CM, Murray CS, Pahkala K, Pers TH, Pfäffle R, Postma DS, Power C, Simpson A, Sengpiel V, Tiesler CM, Torrent M, Uitterlinden AG, van Meurs JB, Vinding R, Waage J, Wardle J, Zeggini E, Zemel BS, Dedoussis GV, Pedersen O, Froguel P, Sunyer J, Plomin R, Jacobsson B, Hansen T, Gonzalez JR, Custovic A, Raitakari OT, Pennell CE, Widén E, Boomsma DI, Koppelman GH, Sebert S, Järvelin MR, Hyppönen E, McCarthy MI, Lindi V, Harri N, Körner A, Bønnelykke K, Heinrich J, Melbye M, Rivadeneira F, Hakonarson H, Ring SM, Smith GD, Sørensen TI, Timpson NJ, Grant SF, Jaddoe VW. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet. 2016 Jan 15; 25(2):389-403. PMID: 26604143; PMCID: PMC4854022 [Available on 01/15/17].
  284. Wolters FJ, de Bruijn RF, Hofman A, Koudstaal PJ, Ikram MA. Cerebral Vasoreactivity, Apolipoprotein E, and the Risk of Dementia: A Population-Based Study. Arterioscler Thromb Vasc Biol. 2016 Jan; 36(1):204-10. PMID: 26586657.
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  285. Jensen RA, Sim X, Smith AV, Li X, Jakobsdóttir J, Cheng CY, Brody JA, Cotch MF, Mcknight B, Klein R, Wang JJ, Kifley A, Harris TB, Launer LJ, Taylor KD, Klein BE, Raffel LJ, Li X, Ikram MA, Klaver CC, van der Lee SJ, Mutlu U, Hofman A, Uitterlinden AG, Liu C, Kraja AT, Mitchell P, Gudnason V, Rotter JI, Boerwinkle E, van Duijn CM, Psaty BM, Wong TY. Novel Genetic Loci Associated With Retinal Microvascular Diameter. Circ Cardiovasc Genet. 2016 Feb; 9(1):45-54. PMID: 26567291; PMCID: PMC4758888 [Available on 02/01/17].
  286. van Leeuwen EM, Huffman JE, Bis JC, Isaacs A, Mulder M, Sabo A, Smith AV, Demissie S, Manichaikul A, Brody JA, Feitosa MF, Duan Q, Schraut KE, Navarro P, van Vliet-Ostaptchouk JV, Zhu G, Mbarek H, Trompet S, Verweij N, Lyytikäinen LP, Deelen J, Nolte IM, van der Laan SW, Davies G, Vermeij-Verdoold AJ, van Oosterhout AA, Vergeer-Drop JM, Arking DE, Trochet H, Medina-Gomez C, Rivadeneira F, Uitterlinden AG, Dehghan A, Franco OH, Sijbrands EJ, Hofman A, White CC, Mychaleckyj JC, Peloso GM, Swertz MA, Willemsen G, de Geus EJ, Milaneschi Y, Penninx BW, Ford I, Buckley BM, de Craen AJ, Starr JM, Deary IJ, Pasterkamp G, Oldehinkel AJ, Snieder H, Slagboom PE, Nikus K, Kähönen M, Lehtimäki T, Viikari JS, Raitakari OT, van der Harst P, Jukema JW, Hottenga JJ, Boomsma DI, Whitfield JB, Montgomery G, Martin NG, Polasek O, Vitart V, Hayward C, Kolcic I, Wright AF, Rudan I, Joshi PK, Wilson JF, Lange LA, Wilson JG, Gudnason V, Harris TB, Morrison AC, Borecki IB, Rich SS, Padmanabhan S, Psaty BM, Rotter JI, Smith BH, Boerwinkle E, Cupples LA, van Duijn C. Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C. NPJ Aging Mech Dis. 2015; 1:15011. PMID: 28721259.
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  287. Sedaghat S, Mattace-Raso FU, Hoorn EJ, Uitterlinden AG, Hofman A, Ikram MA, Franco OH, Dehghan A. Arterial Stiffness and Decline in Kidney Function. Clin J Am Soc Nephrol. 2015 Dec 07; 10(12):2190-7. PMID: 26563380; PMCID: PMC4670762 [Available on 12/07/16].
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  289. de Vries PS, Chasman DI, Sabater-Lleal M, Chen MH, Huffman JE, Steri M, Tang W, Teumer A, Marioni RE, Grossmann V, Hottenga JJ, Trompet S, Müller-Nurasyid M, Zhao JH, Brody JA, Kleber ME, Guo X, Wang JJ, Auer PL, Attia JR, Yanek LR, Ahluwalia TS, Lahti J, Venturini C, Tanaka T, Bielak LF, Joshi PK, Rocanin-Arjo A, Kolcic I, Navarro P, Rose LM, Oldmeadow C, Riess H, Mazur J, Basu S, Goel A, Yang Q, Ghanbari M, Willemsen G, Rumley A, Fiorillo E, de Craen AJ, Grotevendt A, Scott R, Taylor KD, Delgado GE, Yao J, Kifley A, Kooperberg C, Qayyum R, Lopez LM, Berentzen TL, Räikkönen K, Mangino M, Bandinelli S, Peyser PA, Wild S, Trégouët DA, Wright AF, Marten J, Zemunik T, Morrison AC, Sennblad B, Tofler G, de Maat MP, de Geus EJ, Lowe GD, Zoledziewska M, Sattar N, Binder H, Völker U, Waldenberger M, Khaw KT, Mcknight B, Huang J, Jenny NS, Holliday EG, Qi L, Mcevoy MG, Becker DM, Starr JM, Sarin AP, Hysi PG, Hernandez DG, Jhun MA, Campbell H, Hamsten A, Rivadeneira F, Mcardle WL, Slagboom PE, Zeller T, Koenig W, Psaty BM, Haritunians T, Liu J, Palotie A, Uitterlinden AG, Stott DJ, Hofman A, Franco OH, Polasek O, Rudan I, Morange PE, Wilson JF, Kardia SL, Ferrucci L, Spector TD, Eriksson JG, Hansen T, Deary IJ, Becker LC, Scott RJ, Mitchell P, März W, Wareham NJ, Peters A, Greinacher A, Wild PS, Jukema JW, Boomsma DI, Hayward C, Cucca F, Tracy R, Watkins H, Reiner AP, Folsom AR, Ridker PM, O'Donnell CJ, Smith NL, Strachan DP, Dehghan A. A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration. Hum Mol Genet. 2016 Jan 15; 25(2):358-70. PMID: 26561523; PMCID: PMC4715256 [Available on 01/15/17].
  290. Serdarevic F, van Batenburg-Eddes T, Mous SE, White T, Hofman A, Jaddoe VW, Verhulst FC, Ghassabian A, Tiemeier H. Relation of infant motor development with nonverbal intelligence, language comprehension and neuropsychological functioning in childhood: a population-based study. Dev Sci. 2016 Sep; 19(5):790-802. PMID: 26549804.
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  291. Noordam R, Aarts N, Leening MJ, Tiemeier H, Franco OH, Hofman A, Stricker BH, Visser LE. Use of antidepressants and the risk of myocardial infarction in middle-aged and older adults: a matched case-control study. Eur J Clin Pharmacol. 2016 Feb; 72(2):211-8. PMID: 26546336; PMCID: PMC4713708.
  292. Niemeijer MN, van den Berg ME, Deckers JW, Aarnoudse AL, Hofman A, Franco OH, Uitterlinden AG, Rijnbeek PR, Eijgelsheim M, Stricker BH. ABCB1 gene variants, digoxin and risk of sudden cardiac death in a general population. Heart. 2015 Dec; 101(24):1973-9. PMID: 26531821.
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  293. de Groot M, Cremers LG, Ikram MA, Hofman A, Krestin GP, van der Lugt A, Niessen WJ, Vernooij MW. White Matter Degeneration with Aging: Longitudinal Diffusion MR Imaging Analysis. Radiology. 2016 May; 279(2):532-41. PMID: 26536311.
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  294. de Bruijn RF, Heeringa J, Wolters FJ, Franco OH, Stricker BH, Hofman A, Koudstaal PJ, Ikram MA. Association Between Atrial Fibrillation and Dementia in the General Population. JAMA Neurol. 2015 Nov; 72(11):1288-94. PMID: 26389654.
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  295. Bis JC, Sitlani C, Irvin R, Avery CL, Smith AV, Sun F, Evans DS, Musani SK, Li X, Trompet S, Krijthe BP, Harris TB, Quibrera PM, Brody JA, Demissie S, Davis BR, Wiggins KL, Tranah GJ, Lange LA, Sotoodehnia N, Stott DJ, Franco OH, Launer LJ, Stürmer T, Taylor KD, Cupples LA, Eckfeldt JH, Smith NL, Liu Y, Wilson JG, Heckbert SR, Buckley BM, Ikram MA, Boerwinkle E, Chen YD, de Craen AJ, Uitterlinden AG, Rotter JI, Ford I, Hofman A, Sattar N, Slagboom PE, Westendorp RG, Gudnason V, Vasan RS, Lumley T, Cummings SR, Taylor HA, Post W, Jukema JW, Stricker BH, Whitsel EA, Psaty BM, Arnett D. Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. PLoS One. 2015; 10(10):e0140496. PMID: 26516778; PMCID: PMC4627813.
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  297. Bergink AP, Zillikens MC, Van Leeuwen JP, Hofman A, Uitterlinden AG, van Meurs JB. 25-Hydroxyvitamin D and osteoarthritis: A meta-analysis including new data. Semin Arthritis Rheum. 2016 Apr; 45(5):539-46. PMID: 26522138.
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  298. Sonneveld MA, de Maat MP, Portegies ML, Kavousi M, Hofman A, Turecek PL, Rottensteiner H, Scheiflinger F, Koudstaal PJ, Ikram MA, Leebeek FW. Low ADAMTS13 activity is associated with an increased risk of ischemic stroke. Blood. 2015 Dec 17; 126(25):2739-46. PMID: 26511134.
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  299. Liu F, Hamer MA, Heilmann S, Herold C, Moebus S, Hofman A, Uitterlinden AG, Nöthen MM, van Duijn CM, Nijsten TE, Kayser M. Prediction of male-pattern baldness from genotypes. Eur J Hum Genet. 2016 Jun; 24(6):895-902. PMID: 26508577; PMCID: PMC4867459 [Available on 06/01/17].
  300. Steenweg-de Graaff J, Roza SJ, Walstra AN, El Marroun H, Steegers EAP, Jaddoe VWV, Hofman A, Verhulst FC, Tiemeier H, White T. Associations of maternal folic acid supplementation and folate concentrations during pregnancy with foetal and child head growth: the Generation R Study. Eur J Nutr. 2017 Feb; 56(1):65-75. PMID: 26497537.
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  302. van Loon J, Dehghan A, Weihong T, Trompet S, McArdle WL, Asselbergs FF, Chen MH, Lopez LM, Huffman JE, Leebeek FW, Basu S, Stott DJ, Rumley A, Gansevoort RT, Davies G, Wilson JJ, Witteman JC, Cao X, de Craen AJ, Bakker SJ, Psaty BM, Starr JM, Hofman A, Wouter Jukema J, Deary IJ, Hayward C, van der Harst P, Lowe GD, Folsom AR, Strachan DP, Smith N, de Maat MP, O'Donnell C. Genome-wide association studies identify genetic loci for low von Willebrand factor levels. Eur J Hum Genet. 2016 Jul; 24(7):1035-40. PMID: 26486471.
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  305. Dhamo B, Vucic S, Kuijpers MA, Jaddoe VW, Hofman A, Wolvius EB, Ongkosuwito EM. The association between hypodontia and dental development. Clin Oral Investig. 2016 Jul; 20(6):1347-54. PMID: 26462655; PMCID: PMC4914514.
  306. Hofer E, Cavalieri M, Bis JC, DeCarli C, Fornage M, Sigurdsson S, Srikanth V, Trompet S, Verhaaren BF, Wolf C, Yang Q, Adams HH, Amouyel P, Beiser A, Buckley BM, Callisaya M, Chauhan G, de Craen AJ, Dufouil C, van Duijn CM, Ford I, Freudenberger P, Gottesman RF, Gudnason V, Heiss G, Hofman A, Lumley T, Martinez O, Mazoyer B, Moran C, Niessen WJ, Phan T, Psaty BM, Satizabal CL, Sattar N, Schilling S, Shibata DK, Slagboom PE, Smith A, Stott DJ, Taylor KD, Thomson R, Töglhofer AM, Tzourio C, van Buchem M, Wang J, Westendorp RG, Windham BG, Vernooij MW, Zijdenbos A, Beare R, Debette S, Ikram MA, Jukema JW, Launer LJ, Longstreth WT, Mosley TH, Seshadri S, Schmidt H, Schmidt R. White Matter Lesion Progression: Genome-Wide Search for Genetic Influences. Stroke. 2015 Nov; 46(11):3048-57. PMID: 26451028; PMCID: PMC4749149.
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  332. Sedaghat S, Vernooij MW, Loehrer E, Mattace-Raso FU, Hofman A, van der Lugt A, Franco OH, Dehghan A, Ikram MA. Kidney Function and Cerebral Blood Flow: The Rotterdam Study. J Am Soc Nephrol. 2016 Mar; 27(3):715-21. PMID: 26251352; PMCID: PMC4769191 [Available on 03/01/17].
  333. Vidakovic AJ, Gishti O, Steenweg-de Graaff J, Williams MA, Duijts L, Felix JF, Hofman A, Tiemeier H, Jaddoe VW, Gaillard R. Higher Maternal Plasma n-3 PUFA and Lower n-6 PUFA Concentrations in Pregnancy Are Associated with Lower Childhood Systolic Blood Pressure. J Nutr. 2015 Oct; 145(10):2362-8. PMID: 26246325.
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  334. Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE, Altmaier E, He C, Huffman JE, Mihailov E, Porcu E, Robino A, Rose LM, Schick UM, Stolk L, Teumer A, Thompson DJ, Traglia M, Wang CA, Yerges-Armstrong LM, Antoniou AC, Barbieri C, Coviello AD, Cucca F, Demerath EW, Dunning AM, Gandin I, Grove ML, Gudbjartsson DF, Hocking LJ, Hofman A, Huang J, Jackson RD, Karasik D, Kriebel J, Lange EM, Lange LA, Langenberg C, Li X, Luan J, Mägi R, Morrison AC, Padmanabhan S, Pirie A, Polasek O, Porteous D, Reiner AP, Rivadeneira F, Rudan I, Sala CF, Schlessinger D, Scott RA, Stöckl D, Visser JA, Völker U, Vozzi D, Wilson JG, Zygmunt M, Boerwinkle E, Buring JE, Crisponi L, Easton DF, Hayward C, Hu FB, Liu S, Metspalu A, Pennell CE, Ridker PM, Strauch K, Streeten EA, Toniolo D, Uitterlinden AG, Ulivi S, Völzke H, Wareham NJ, Wellons M, Franceschini N, Chasman DI, Thorsteinsdottir U, Murray A, Stefansson K, Murabito JM, Ong KK, Perry JR. Rare coding variants and X-linked loci associated with age at menarche. Nat Commun. 2015 Aug 04; 6:7756. PMID: 26239645; PMCID: PMC4538850.
  335. Wijtzes AI, Jansen W, Jaddoe VW, Franco OH, Hofman A, van Lenthe FJ, Raat H. Social Inequalities in Young Children's Meal Skipping Behaviors: The Generation R Study. PLoS One. 2015; 10(7):e0134487. PMID: 26225757; PMCID: PMC4520523.
  336. Medina-Gómez C, Chesi A, Heppe DH, Zemel BS, Yin JL, Kalkwarf HJ, Hofman A, Lappe JM, Kelly A, Kayser M, Oberfield SE, Gilsanz V, Uitterlinden AG, Shepherd JA, Jaddoe VW, Grant SF, Lao O, Rivadeneira F. BMD Loci Contribute to Ethnic and Developmental Differences in Skeletal Fragility across Populations: Assessment of Evolutionary Selection Pressures. Mol Biol Evol. 2015 Nov; 32(11):2961-72. PMID: 26226985; PMCID: PMC4651235.
  337. Maljuric NM, Noordam R, Aarts N, Niemeijer MN, van den Berg ME, Hofman A, Kors JA, Stricker BH, Visser LE. Use of selective serotonin re-uptake inhibitors and the heart rate corrected QT interval in a real-life setting: the population-based Rotterdam Study. Br J Clin Pharmacol. 2015 Oct; 80(4):698-705. PMID: 25966843; PMCID: PMC4594706 [Available on 10/01/16].
  338. Adams HH, Verlinden VJ, Callisaya ML, van Duijn CM, Hofman A, Thomson R, Uitterlinden AG, Vernooij MW, van der Geest JN, Srikanth V, Ikram MA. Heritability and Genome-Wide Association Analyses of Human Gait Suggest Contribution of Common Variants. J Gerontol A Biol Sci Med Sci. 2016 Jun; 71(6):740-6. PMID: 26219847; PMCID: PMC4888380 [Available on 06/01/17].
  339. Plompen EP, Darwish Murad S, Hansen BE, Loth DW, Schouten JN, Taimr P, Hofman A, Uitterlinden AG, Stricker BH, Janssen HL, Leebeek FW. Prothrombotic genetic risk factors are associated with an increased risk of liver fibrosis in the general population: The Rotterdam Study. J Hepatol. 2015 Dec; 63(6):1459-65. PMID: 26226452.
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  340. Bautista Niño PK, Tielemans MJ, Schalekamp-Timmermans S, Steenweg-de Graaff J, Hofman A, Tiemeier H, Jaddoe VW, Steegers EA, Felix JF, Franco OH. Maternal fish consumption, fatty acid levels and angiogenic factors: The Generation R Study. Placenta. 2015 Oct; 36(10):1178-84. PMID: 26278058.
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  341. de Kruijf M, Peters MJ, C Jacobs L, Tiemeier H, Nijsten T, Hofman A, Uitterlinden AG, Huygen FJ, van Meurs JB. Determinants for Quantitative Sensory Testing and the Association with Chronic Musculoskeletal Pain in the General Elderly Population. Pain Pract. 2016 Sep; 16(7):831-41. PMID: 26205731.
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  342. Braun KV, Voortman T, Kiefte-de Jong JC, Jaddoe VW, Hofman A, Franco OH, van den Hooven EH. Dietary Intakes of Folic Acid and Methionine in Early Childhood Are Associated with Body Composition at School Age. J Nutr. 2015 Sep; 145(9):2123-9. PMID: 26203097.
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  343. de Bruijn RF, Bos MJ, Portegies ML, Hofman A, Franco OH, Koudstaal PJ, Ikram MA. The potential for prevention of dementia across two decades: the prospective, population-based Rotterdam Study. BMC Med. 2015 Jul 21; 13:132. PMID: 26195085; PMCID: PMC4509699.
  344. Lorenz MW, Price JF, Robertson C, Bots ML, Polak JF, Poppert H, Kavousi M, Dörr M, Stensland E, Ducimetiere P, Ronkainen K, Kiechl S, Sitzer M, Rundek T, Lind L, Liu J, Bergström G, Grigore L, Bokemark L, Friera A, Yanez D, Bickel H, Ikram MA, Völzke H, Johnsen SH, Empana JP, Tuomainen TP, Willeit P, Steinmetz H, Desvarieux M, Xie W, Schmidt C, Norata GD, Suarez C, Sander D, Hofman A, Schminke U, Mathiesen E, Plichart M, Kauhanen J, Willeit J, Sacco RL, McLachlan S, Zhao D, Fagerberg B, Catapano AL, Gabriel R, Franco OH, Bülbül A, Scheckenbach F, Pflug A, Gao L, Thompson SG. Carotid intima-media thickness progression and risk of vascular events in people with diabetes: results from the PROG-IMT collaboration. Diabetes Care. 2015 Oct; 38(10):1921-9. PMID: 26180107; PMCID: PMC4580609 [Available on 10/01/16].
  345. de Kruijf M, Verlinden VJ, Huygen FJ, Hofman A, van der Geest JN, Uitterlinden AG, Bierma-Zeinstra SM, Ikram MA, van Meurs JB. Chronic joint pain in the lower body is associated with gait differences independent from radiographic osteoarthritis. Gait Posture. 2015 Sep; 42(3):354-9. PMID: 26210905.
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  346. Mahmoudpour SH, Asselbergs FW, de Keyser CE, Souverein PC, Hofman A, Stricker BH, de Boer A, Maitland-van der Zee AH. Change in prescription pattern as a potential marker for adverse drug reactions of angiotensin converting enzyme inhibitors. Int J Clin Pharm. 2015 Dec; 37(6):1095-103. PMID: 26159317; PMCID: PMC4619457.
  347. Dhana K, Kavousi M, Ikram MA, Tiemeier HW, Hofman A, Franco OH. Body shape index in comparison with other anthropometric measures in prediction of total and cause-specific mortality. J Epidemiol Community Health. 2016 Jan; 70(1):90-6. PMID: 26160362.
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  348. Niemeijer MN, van den Berg ME, Deckers JW, Franco OH, Hofman A, Kors JA, Stricker BH, Rijnbeek PR, Eijgelsheim M. Consistency of heart rate-QTc prolongation consistency and sudden cardiac death: The Rotterdam Study. Heart Rhythm. 2015 Oct; 12(10):2078-85. PMID: 26165945.
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  349. Bahadoer S, Gaillard R, Felix JF, Raat H, Renders CM, Hofman A, Steegers EA, Jaddoe VW. Ethnic disparities in maternal obesity and weight gain during pregnancy. The Generation R Study. Eur J Obstet Gynecol Reprod Biol. 2015 Oct; 193:51-60. PMID: 26232727.
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  350. Zonneveld HI, Loehrer EA, Hofman A, Niessen WJ, van der Lugt A, Krestin GP, Ikram MA, Vernooij MW. The bidirectional association between reduced cerebral blood flow and brain atrophy in the general population. J Cereb Blood Flow Metab. 2015 Nov; 35(11):1882-7. PMID: 26154865; PMCID: PMC4635245 [Available on 11/01/16].
  351. Noordam R, Aarts N, de Keyser CE, Hofman A, Stricker BH, Visser LE. Antidepressants with a high serotonin reuptake transporter affinity and serum lipid levels in a population-based study in older adults. J Psychopharmacol. 2015 Oct; 29(10):1112-8. PMID: 26152323.
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  352. Liefaard MC, Ligthart S, Vitezova A, Hofman A, Uitterlinden AG, Kiefte-de Jong JC, Franco OH, Zillikens MC, Dehghan A. Vitamin D and C-Reactive Protein: A Mendelian Randomization Study. PLoS One. 2015; 10(7):e0131740. PMID: 26147588; PMCID: PMC4492676.
  353. Akoudad S, Portegies ML, Koudstaal PJ, Hofman A, van der Lugt A, Ikram MA, Vernooij MW. Cerebral Microbleeds Are Associated With an Increased Risk of Stroke: The Rotterdam Study. Circulation. 2015 Aug 11; 132(6):509-16. PMID: 26137955.
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  354. Gishti O, Jaddoe VW, Duijts L, Steegers E, Reiss I, Hofman A, Wong TY, Ikram MK, Gaillard R. Impact of birth parameters and early life growth patterns on retinal microvascular structure in children: The Generation R Study. J Hypertens. 2015 Jul; 33(7):1429-37. PMID: 25799210.
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  355. Kieboom BC, Kiefte-de Jong JC, Eijgelsheim M, Franco OH, Kuipers EJ, Hofman A, Zietse R, Stricker BH, Hoorn EJ. Proton pump inhibitors and hypomagnesemia in the general population: a population-based cohort study. Am J Kidney Dis. 2015 Nov; 66(5):775-82. PMID: 26123862.
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  356. Huffman JE, de Vries PS, Morrison AC, Sabater-Lleal M, Kacprowski T, Auer PL, Brody JA, Chasman DI, Chen MH, Guo X, Lin LA, Marioni RE, Müller-Nurasyid M, Yanek LR, Pankratz N, Grove ML, de Maat MP, Cushman M, Wiggins KL, Qi L, Sennblad B, Harris SE, Polasek O, Riess H, Rivadeneira F, Rose LM, Goel A, Taylor KD, Teumer A, Uitterlinden AG, Vaidya D, Yao J, Tang W, Levy D, Waldenberger M, Becker DM, Folsom AR, Giulianini F, Greinacher A, Hofman A, Huang CC, Kooperberg C, Silveira A, Starr JM, Strauch K, Strawbridge RJ, Wright AF, McKnight B, Franco OH, Zakai N, Mathias RA, Psaty BM, Ridker PM, Tofler GH, Völker U, Watkins H, Fornage M, Hamsten A, Deary IJ, Boerwinkle E, Koenig W, Rotter JI, Hayward C, Dehghan A, Reiner AP, O'Donnell CJ, Smith NL. Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF. Blood. 2015 Sep 10; 126(11):e19-29. PMID: 26105150; PMCID: PMC4566813.
  357. Moreira EM, Gall H, Leening MJ, Lahousse L, Loth DW, Krijthe BP, Kiefte-de Jong JC, Brusselle GG, Hofman A, Stricker BH, Ghofrani HA, Franco OH, Felix JF. Prevalence of Pulmonary Hypertension in the General Population: The Rotterdam Study. PLoS One. 2015; 10(6):e0130072. PMID: 26102085; PMCID: PMC4478029.
  358. Niemeijer MN, Leening MJ, van den Berg ME, Hofman A, Franco OH, Deckers JW, Rijnbeek PR, Stricker BH, Eijgelsheim M. Subclinical Abnormalities in Echocardiographic Parameters and Risk of Sudden Cardiac Death in a General Population: The Rotterdam Study. J Card Fail. 2016 Jan; 22(1):17-23. PMID: 26093333.
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  359. Sedaghat S, Cremers LG, de Groot M, Hoorn EJ, Hofman A, van der Lugt A, Franco OH, Vernooij MW, Dehghan A, Ikram MA. Kidney function and microstructural integrity of brain white matter. Neurology. 2015 Jul 14; 85(2):154-61. PMID: 26085601.
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  360. Mous SE, Hammerschlag AR, Polderman TJ, Verhulst FC, Tiemeier H, van der Lugt A, Jaddoe VW, Hofman A, White T, Posthuma D. A Population-Based Imaging Genetics Study of Inattention/Hyperactivity: Basal Ganglia and Genetic Pathways. J Am Acad Child Adolesc Psychiatry. 2015 Sep; 54(9):745-52. PMID: 26299296.
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  361. Krishnadath IS, Smits CC, Jaddoe VW, Hofman A, Toelsie JR. A National Surveillance Survey on Noncommunicable Disease Risk Factors: Suriname Health Study Protocol. JMIR Res Protoc. 2015 Jun 17; 4(2):e75. PMID: 26085372; PMCID: PMC4526944.
  362. Muka T, Trajanoska K, Kiefte-de Jong JC, Oei L, Uitterlinden AG, Hofman A, Dehghan A, Zillikens MC, Franco OH, Rivadeneira F. The Association between Metabolic Syndrome, Bone Mineral Density, Hip Bone Geometry and Fracture Risk: The Rotterdam Study. PLoS One. 2015; 10(6):e0129116. PMID: 26066649; PMCID: PMC4466576.
  363. Power RA, Steinberg S, Bjornsdottir G, Rietveld CA, Abdellaoui A, Nivard MM, Johannesson M, Galesloot TE, Hottenga JJ, Willemsen G, Cesarini D, Benjamin DJ, Magnusson PK, Ullén F, Tiemeier H, Hofman A, van Rooij FJ, Walters GB, Sigurdsson E, Thorgeirsson TE, Ingason A, Helgason A, Kong A, Kiemeney LA, Koellinger P, Boomsma DI, Gudbjartsson D, Stefansson H, Stefansson K. Polygenic risk scores for schizophrenia and bipolar disorder predict creativity. Nat Neurosci. 2015 Jul; 18(7):953-5. PMID: 26053403.
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  364. Cuellar-Partida G, Springelkamp H, Lucas SE, Yazar S, Hewitt AW, Iglesias AI, Montgomery GW, Martin NG, Pennell CE, van Leeuwen EM, Verhoeven VJ, Hofman A, Uitterlinden AG, Ramdas WD, Wolfs RC, Vingerling JR, Brown MA, Mills RA, Craig JE, Klaver CC, van Duijn CM, Burdon KP, MacGregor S, Mackey DA. WNT10A exonic variant increases the risk of keratoconus by decreasing corneal thickness. Hum Mol Genet. 2015 Sep 01; 24(17):5060-8. PMID: 26049155.
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  365. Riba-Llena I, Koek M, Verhaaren BF, Vrooman HA, van der Lugt A, Hofman A, Ikram MA, Vernooij MW. Small cortical infarcts: prevalence, determinants, and cognitive correlates in the general population. Int J Stroke. 2015 Oct; 10 Suppl A100:18-24. PMID: 26043763.
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  366. Kraja B, Muka T, Ruiter R, de Keyser CE, Hofman A, Franco OH, Stricker BH, Kiefte-de Jong JC. Dietary Fiber Intake Modifies the Positive Association between n-3 PUFA Intake and Colorectal Cancer Risk in a Caucasian Population. J Nutr. 2015 Aug; 145(8):1709-16. PMID: 26041678.
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  367. van Berkel AC, den Dekker HT, Jaddoe VW, Reiss IK, Gaillard R, Hofman A, de Jongste JC, Duijts L. Mode of delivery and childhood fractional exhaled nitric oxide, interrupter resistance and asthma: the Generation R study. Pediatr Allergy Immunol. 2015 Jun; 26(4):330-6. PMID: 25845270.
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  368. de Keyser CE, de Lima FV, de Jong FH, Hofman A, de Rijke YB, Uitterlinden AG, Visser LE, Stricker BH. Use of statins is associated with lower serum total and non-sex hormone-binding globulin-bound testosterone levels in male participants of the Rotterdam Study. Eur J Endocrinol. 2015 Aug; 173(2):155-65. PMID: 26034077.
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  369. Noordam R, Aarts N, Tiemeier H, Hofman A, Stricker BH, Visser LE. Sex-specific association between antidepressant use and body weight in a population-based study in older adults. J Clin Psychiatry. 2015 Jun; 76(6):e745-51. PMID: 26132681.
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  370. Noordam R, van den Berg ME, Niemeijer MN, Aarts N, Leening MJ, Deckers JW, Hofman A, Rijnbeek PR, Eijgelsheim M, Kors JA, Stricker BH, Visser LE. Assessing Prolongation of the Heart Rate Corrected QT Interval in Users of Tricyclic Antidepressants: Advice to Use Fridericia Rather Than Bazett's Correction. J Clin Psychopharmacol. 2015 Jun; 35(3):260-5. PMID: 25856783.
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  371. van Nistelrooij AM, van der Korput HA, Broer L, van Marion R, van Berge Henegouwen MI, van Noesel CJ, Biermann K, Spaander MC, Tilanus HW, van Lanschot JJ, Hofman A, Uitterlinden AG, Wijnhoven BP, Dinjens WN. Single nucleotide polymorphisms in CRTC1 and BARX1 are associated with esophageal adenocarcinoma. J Carcinog. 2015; 14:5. PMID: 26085818; PMCID: PMC4453126.
  372. Nettleton JA, Follis JL, Ngwa JS, Smith CE, Ahmad S, Tanaka T, Wojczynski MK, Voortman T, Lemaitre RN, Kristiansson K, Nuotio ML, Houston DK, Perälä MM, Qi Q, Sonestedt E, Manichaikul A, Kanoni S, Ganna A, Mikkilä V, North KE, Siscovick DS, Harald K, Mckeown NM, Johansson I, Rissanen H, Liu Y, Lahti J, Hu FB, Bandinelli S, Rukh G, Rich S, Booij L, Dmitriou M, Ax E, Raitakari O, Mukamal K, Männistö S, Hallmans G, Jula A, Ericson U, Jacobs DR, Van Rooij FJ, Deloukas P, Sjögren P, Kähönen M, Djousse L, Perola M, Barroso I, Hofman A, Stirrups K, Viikari J, Uitterlinden AG, Kalafati IP, Franco OH, Mozaffarian D, Salomaa V, Borecki IB, Knekt P, Kritchevsky SB, Eriksson JG, Dedoussis GV, Qi L, Ferrucci L, Orho-Melander M, Zillikens MC, Ingelsson E, Lehtimäki T, Renström F, Cupples LA, Loos RJ, Franks PW. Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry. Hum Mol Genet. 2015 Aug 15; 24(16):4728-38. PMID: 25994509; PMCID: PMC4512626.
  373. Jansen MA, van den Heuvel D, van Zelm MC, Jaddoe VW, Hofman A, de Jongste JC, Hooijkaas H, Moll HA. Decreased memory B cells and increased CD8 memory T cells in blood of breastfed children: the generation R study. PLoS One. 2015; 10(5):e0126019. PMID: 25993335; PMCID: PMC4436360.
  374. Verlinden M, Jansen PW, Veenstra R, Jaddoe VW, Hofman A, Verhulst FC, Shaw P, Tiemeier H. Preschool Attention-Deficit/Hyperactivity and Oppositional Defiant Problems as Antecedents of School Bullying. J Am Acad Child Adolesc Psychiatry. 2015 Jul; 54(7):571-9. PMID: 26088662.
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  375. Steenaard RV, Ligthart S, Stolk L, Peters MJ, van Meurs JB, Uitterlinden AG, Hofman A, Franco OH, Dehghan A. Tobacco smoking is associated with methylation of genes related to coronary artery disease. Clin Epigenetics. 2015; 7:54. PMID: 26015811; PMCID: PMC4443552.
  376. Williams KM, Bertelsen G, Cumberland P, Wolfram C, Verhoeven VJ, Anastasopoulos E, Buitendijk GH, Cougnard-Grégoire A, Creuzot-Garcher C, Erke MG, Hogg R, Höhn R, Hysi P, Khawaja AP, Korobelnik JF, Ried J, Vingerling JR, Bron A, Dartigues JF, Fletcher A, Hofman A, Kuijpers RW, Luben RN, Oxele K, Topouzis F, von Hanno T, Mirshahi A, Foster PJ, van Duijn CM, Pfeiffer N, Delcourt C, Klaver CC, Rahi J, Hammond CJ. Increasing Prevalence of Myopia in Europe and the Impact of Education. Ophthalmology. 2015 Jul; 122(7):1489-97. PMID: 25983215; PMCID: PMC4504030.
  377. Miliku K, Voortman T, van den Hooven EH, Hofman A, Franco OH, Jaddoe VW. First-trimester maternal protein intake and childhood kidney outcomes: the Generation R Study. Am J Clin Nutr. 2015 Jul; 102(1):123-9. PMID: 25971715.
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  378. Liu F, Visser M, Duffy DL, Hysi PG, Jacobs LC, Lao O, Zhong K, Walsh S, Chaitanya L, Wollstein A, Zhu G, Montgomery GW, Henders AK, Mangino M, Glass D, Bataille V, Sturm RA, Rivadeneira F, Hofman A, van IJcken WF, Uitterlinden AG, Palstra RJ, Spector TD, Martin NG, Nijsten TE, Kayser M. Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up. Hum Genet. 2015 Aug; 134(8):823-35. PMID: 25963972; PMCID: PMC4495261.
  379. Korevaar TI, Steegers EA, de Rijke YB, Schalekamp-Timmermans S, Visser WE, Hofman A, Jaddoe VW, Tiemeier H, Visser TJ, Medici M, Peeters RP. Reference ranges and determinants of total hCG levels during pregnancy: the Generation R Study. Eur J Epidemiol. 2015 Sep; 30(9):1057-66. PMID: 25963653; PMCID: PMC4584104.
  380. Voortman T, Bakker H, Sedaghat S, Kiefte-de Jong JC, Hofman A, Jaddoe VW, Franco OH, van den Hooven EH. Protein intake in infancy and kidney size and function at the age of 6 years: The Generation R Study. Pediatr Nephrol. 2015 Oct; 30(10):1825-33. PMID: 25956700; PMCID: PMC4549379.
  381. Westra HJ, Arends D, Esko T, Peters MJ, Schurmann C, Schramm K, Kettunen J, Yaghootkar H, Fairfax BP, Andiappan AK, Li Y, Fu J, Karjalainen J, Platteel M, Visschedijk M, Weersma RK, Kasela S, Milani L, Tserel L, Peterson P, Reinmaa E, Hofman A, Uitterlinden AG, Rivadeneira F, Homuth G, Petersmann A, Lorbeer R, Prokisch H, Meitinger T, Herder C, Roden M, Grallert H, Ripatti S, Perola M, Wood AR, Melzer D, Ferrucci L, Singleton AB, Hernandez DG, Knight JC, Melchiotti R, Lee B, Poidinger M, Zolezzi F, Larbi A, Wang de Y, van den Berg LH, Veldink JH, Rotzschke O, Makino S, Salomaa V, Strauch K, Völker U, van Meurs JB, Metspalu A, Wijmenga C, Jansen RC, Franke L. Cell Specific eQTL Analysis without Sorting Cells. PLoS Genet. 2015 May; 11(5):e1005223. PMID: 25955312; PMCID: PMC4425538.
  382. van den Bouwhuijsen QJ, Bos D, Ikram MA, Hofman A, Krestin GP, Franco OH, van der Lugt A, Vernooij MW. Coexistence of Calcification, Intraplaque Hemorrhage and Lipid Core within the Asymptomatic Atherosclerotic Carotid Plaque: The Rotterdam Study. Cerebrovasc Dis. 2015; 39(5-6):319-24. PMID: 25966822.
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  383. de Vries PS, Kavousi M, Ligthart S, Uitterlinden AG, Hofman A, Franco OH, Dehghan A. Incremental predictive value of 152 single nucleotide polymorphisms in the 10-year risk prediction of incident coronary heart disease: the Rotterdam Study. Int J Epidemiol. 2015 Apr; 44(2):682-8. PMID: 25953786.
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  384. Hoeven TA, Kavousi M, Ikram MA, van Meurs JB, Bindels PJ, Hofman A, Franco OH, Bierma-Zeinstra SM. Markers of atherosclerosis in relation to presence and progression of knee osteoarthritis: a population-based cohort study. Rheumatology (Oxford). 2015 Sep; 54(9):1692-8. PMID: 25953699.
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  385. de Vries PS, Boender J, Sonneveld MA, Rivadeneira F, Ikram MA, Rottensteiner H, Hofman A, Uitterlinden AG, Leebeek FW, Franco OH, Dehghan A, de Maat MP. Genetic variants in the ADAMTS13 and SUPT3H genes are associated with ADAMTS13 activity. Blood. 2015 Jun 18; 125(25):3949-55. PMID: 25934476.
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  386. Vitezova A, Cartolano NS, Heeringa J, Zillikens MC, Hofman A, Franco OH, Kiefte-de Jong JC. Vitamin D and the risk of atrial fibrillation--the Rotterdam Study. PLoS One. 2015; 10(5):e0125161. PMID: 25933375; PMCID: PMC4416919.
  387. Zhang L, Buitendijk GH, Lee K, Sonka M, Springelkamp H, Hofman A, Vingerling JR, Mullins RF, Klaver CC, Abràmoff MD. Validity of Automated Choroidal Segmentation in SS-OCT and SD-OCT. Invest Ophthalmol Vis Sci. 2015 May; 56(5):3202-11. PMID: 26024104; PMCID: PMC4451615.
  388. Sanchez-Juan P, Bishop MT, Kovacs GG, Calero M, Aulchenko YS, Ladogana A, Boyd A, Lewis V, Ponto C, Calero O, Poleggi A, Carracedo Á, van der Lee SJ, Ströbel T, Rivadeneira F, Hofman A, Haïk S, Combarros O, Berciano J, Uitterlinden AG, Collins SJ, Budka H, Brandel JP, Laplanche JL, Pocchiari M, Zerr I, Knight RS, Will RG, van Duijn CM. A genome wide association study links glutamate receptor pathway to sporadic Creutzfeldt-Jakob disease risk. PLoS One. 2014; 10(4):e0123654. PMID: 25918841; PMCID: PMC4412535.
  389. Lahousse L, Niemeijer MN, van den Berg ME, Rijnbeek PR, Joos GF, Hofman A, Franco OH, Deckers JW, Eijgelsheim M, Stricker BH, Brusselle GG. Chronic obstructive pulmonary disease and sudden cardiac death: the Rotterdam study. Eur Heart J. 2015 Jul 14; 36(27):1754-61. PMID: 25920404.
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  390. Mirza SS, de Bruijn RF, Koudstaal PJ, van den Meiracker AH, Franco OH, Hofman A, Tiemeier H, Ikram MA. The N-terminal pro B-type natriuretic peptide, and risk of dementia and cognitive decline: a 10-year follow-up study in the general population. J Neurol Neurosurg Psychiatry. 2016 Apr; 87(4):356-62. PMID: 25918047.
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  391. Adams HH, de Bruijn RF, Hofman A, Uitterlinden AG, van Duijn CM, Vernooij MW, Koudstaal PJ, Ikram MA. Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia. Alzheimers Dement. 2015 Nov; 11(11):1277-85. PMID: 25916564.
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  392. Punwasi RV, Monnereau C, Hofman A, Jaddoe VW, Felix JF. The Influence of Known Genetic Variants on Subclinical Cardiovascular Outcomes in Childhood: Generation R Study. Circ Cardiovasc Genet. 2015 Aug; 8(4):596-602. PMID: 25911650.
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  393. Bos D, Shahzad R, van Walsum T, van Vliet LJ, Franco OH, Hofman A, Niessen WJ, Vernooij MW, van der Lugt A. Epicardial fat volume is related to atherosclerotic calcification in multiple vessel beds. Eur Heart J Cardiovasc Imaging. 2015 Nov; 16(11):1264-9. PMID: 25908795.
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  394. Chaker L, Buitendijk GH, Dehghan A, Medici M, Hofman A, Vingerling JR, Franco OH, Klaver CC, Peeters RP. Thyroid function and age-related macular degeneration: a prospective population-based cohort study--the Rotterdam Study. BMC Med. 2015 Apr 23; 13:94. PMID: 25903050; PMCID: PMC4407352.
  395. Muka T, Kiefte-de Jong JC, Hofman A, Dehghan A, Rivadeneira F, Franco OH. Polyunsaturated fatty acids and serum C-reactive protein: the Rotterdam study. Am J Epidemiol. 2015 Jun 01; 181(11):846-56. PMID: 25899092.
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  396. Gishti O, Gaillard R, Felix JF, Bouthoorn S, Steegers E, Raat H, Hofman A, Duijts L, Franco OH, Jaddoe VW. Early origins of ethnic disparities in cardiovascular risk factors. Prev Med. 2015 Jul; 76:84-91. PMID: 25895837.
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  397. Feigin VL, Krishnamurthi R, Bhattacharjee R, Parmar P, Theadom A, Hussein T, Purohit M, Hume P, Abbott M, Rush E, Kasabov N, Crezee I, Frielick S, Barker-Collo S, Barber PA, Arroll B, Poulton R, Ratnasabathy Y, Tobias M, Cabral N, Martins SC, Furtado LE, Lindsay P, Saposnik G, Giroud M, Béjot Y, Hacke W, Mehndiratta MM, Pandian JD, Gupta S, Padma V, Mandal DK, Kokubo Y, Ibrahim NM, Sahathevan R, Fu H, Wang W, Liu L, Hou ZG, Goncalves AF, Correia M, Varakin Y, Kravchenko M, Piradov M, Saadah M, Thrift AG, Cadilhac D, Davis S, Donnan G, Lopez AD, Hankey GJ, Maujean A, Kendall E, Brainin M, Abd-Allah F, Bornstein NM, Caso V, Marquez-Romero JM, Akinyemi RO, Bin Dhim NF, Norrving B, Sindi S, Kivipelto M, Mendis S, Ikram MA, Hofman A, Mirza SS, Rothwell PM, Sandercock P, Shakir R, Sacco RL, Culebras A, Roth GA, Moradi-Lakeh M, Murray C, Narayan KM, Mensah GA, Wiebers D, Moran AE. New strategy to reduce the global burden of stroke. Stroke. 2015 Jun; 46(6):1740-7. PMID: 25882050.
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  398. Luik AI, Zuurbier LA, Hofman A, Van Someren EJ, Ikram MA, Tiemeier H. Associations of the 24-h activity rhythm and sleep with cognition: a population-based study of middle-aged and elderly persons. Sleep Med. 2015 Jul; 16(7):850-5. PMID: 26028055.
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  399. Chaker L, Baumgartner C, den Elzen WP, Ikram MA, Blum MR, Collet TH, Bakker SJ, Dehghan A, Drechsler C, Luben RN, Hofman A, Portegies ML, Medici M, Iervasi G, Stott DJ, Ford I, Bremner A, Wanner C, Ferrucci L, Newman AB, Dullaart RP, Sgarbi JA, Ceresini G, Maciel RM, Westendorp RG, Jukema JW, Imaizumi M, Franklyn JA, Bauer DC, Walsh JP, Razvi S, Khaw KT, Cappola AR, Völzke H, Franco OH, Gussekloo J, Rodondi N, Peeters RP. Subclinical Hypothyroidism and the Risk of Stroke Events and Fatal Stroke: An Individual Participant Data Analysis. J Clin Endocrinol Metab. 2015 Jun; 100(6):2181-91. PMID: 25856213; PMCID: PMC4454799.
  400. Postmus I, Deelen J, Sedaghat S, Trompet S, de Craen AJ, Heijmans BT, Franco OH, Hofman A, Dehghan A, Slagboom PE, Westendorp RG, Jukema JW. LDL cholesterol still a problem in old age? A Mendelian randomization study. Int J Epidemiol. 2015 Apr; 44(2):604-12. PMID: 25855712.
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  401. van der Lee SJ, Holstege H, Wong TH, Jakobsdottir J, Bis JC, Chouraki V, van Rooij JG, Grove ML, Smith AV, Amin N, Choi SH, Beiser AS, Garcia ME, van IJcken WF, Pijnenburg YA, Louwersheimer E, Brouwer RW, van den Hout MC, Oole E, Eirkisdottir G, Levy D, Rotter JI, Emilsson V, O'Donnell CJ, Aspelund T, Uitterlinden AG, Launer LJ, Hofman A, Boerwinkle E, Psaty BM, DeStefano AL, Scheltens P, Seshadri S, van Swieten JC, Gudnason V, van der Flier WM, Ikram MA, van Duijn CM. PLD3 variants in population studies. Nature. 2015 Apr 02; 520(7545):E2-3. PMID: 25832410; PMCID: PMC4544703.
  402. Reinthaler EM, Dejanovic B, Lal D, Semtner M, Merkler Y, Reinhold A, Pittrich DA, Hotzy C, Feucht M, Steinböck H, Gruber-Sedlmayr U, Ronen GM, Neophytou B, Geldner J, Haberlandt E, Muhle H, Ikram MA, van Duijn CM, Uitterlinden AG, Hofman A, Altmüller J, Kawalia A, Toliat MR, Nürnberg P, Lerche H, Nothnagel M, Thiele H, Sander T, Meier JC, Schwarz G, Neubauer BA, Zimprich F. Rare variants in ?-aminobutyric acid type A receptor genes in rolandic epilepsy and related syndromes. Ann Neurol. 2015 Jun; 77(6):972-86. PMID: 25726841.
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  404. Huffman JE, Albrecht E, Teumer A, Mangino M, Kapur K, Johnson T, Kutalik Z, Pirastu N, Pistis G, Lopez LM, Haller T, Salo P, Goel A, Li M, Tanaka T, Dehghan A, Ruggiero D, Malerba G, Smith AV, Nolte IM, Portas L, Phipps-Green A, Boteva L, Navarro P, Johansson A, Hicks AA, Polasek O, Esko T, Peden JF, Harris SE, Murgia F, Wild SH, Tenesa A, Tin A, Mihailov E, Grotevendt A, Gislason GK, Coresh J, D'Adamo P, Ulivi S, Vollenweider P, Waeber G, Campbell S, Kolcic I, Fisher K, Viigimaa M, Metter JE, Masciullo C, Trabetti E, Bombieri C, Sorice R, Döring A, Reischl E, Strauch K, Hofman A, Uitterlinden AG, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Dalbeth N, Stamp L, Smit JH, Kirin M, Nagaraja R, Nauck M, Schurmann C, Budde K, Farrington SM, Theodoratou E, Jula A, Salomaa V, Sala C, Hengstenberg C, Burnier M, Mägi R, Klopp N, Kloiber S, Schipf S, Ripatti S, Cabras S, Soranzo N, Homuth G, Nutile T, Munroe PB, Hastie N, Campbell H, Rudan I, Cabrera C, Haley C, Franco OH, Merriman TR, Gudnason V, Pirastu M, Penninx BW, Snieder H, Metspalu A, Ciullo M, Pramstaller PP, van Duijn CM, Ferrucci L, Gambaro G, Deary IJ, Dunlop MG, Wilson JF, Gasparini P, Gyllensten U, Spector TD, Wright AF, Hayward C, Watkins H, Perola M, Bochud M, Kao WH, Caulfield M, Toniolo D, Völzke H, Gieger C, Köttgen A, Vitart V. Modulation of genetic associations with serum urate levels by body-mass-index in humans. PLoS One. 2015; 10(3):e0119752. PMID: 25811787; PMCID: PMC4374966.
  405. Ringoot AP, Tiemeier H, Jaddoe VW, So P, Hofman A, Verhulst FC, Jansen PW. Parental depression and child well-being: young children's self-reports helped addressing biases in parent reports. J Clin Epidemiol. 2015 Aug; 68(8):928-38. PMID: 25900418.
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  406. Verkouteren JAC, Pardo LM, Uitterlinden AG, Hofman A, Nijsten T. Common Variants Affecting Susceptibility to Develop Multiple Basal Cell Carcinomas. J Invest Dermatol. 2015 Aug; 135(8):2135-2138. PMID: 25801793.
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  407. Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C, Joehanes R, Johnson AD, Yao C, Ying SX, Courchesne P, Milani L, Raghavachari N, Wang R, Liu P, Reinmaa E, Dehghan A, Hofman A, Uitterlinden AG, Hernandez DG, Bandinelli S, Singleton A, Melzer D, Metspalu A, Carstensen M, Grallert H, Herder C, Meitinger T, Peters A, Roden M, Waldenberger M, Dörr M, Felix SB, Zeller T, Vasan R, O'Donnell CJ, Munson PJ, Yang X, Prokisch H, Völker U, van Meurs JB, Ferrucci L, Levy D. A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet. 2015 Mar; 11(3):e1005035. PMID: 25785607; PMCID: PMC4365001.
  408. Williams KM, Verhoeven VJ, Cumberland P, Bertelsen G, Wolfram C, Buitendijk GH, Hofman A, van Duijn CM, Vingerling JR, Kuijpers RW, Höhn R, Mirshahi A, Khawaja AP, Luben RN, Erke MG, von Hanno T, Mahroo O, Hogg R, Gieger C, Cougnard-Grégoire A, Anastasopoulos E, Bron A, Dartigues JF, Korobelnik JF, Creuzot-Garcher C, Topouzis F, Delcourt C, Rahi J, Meitinger T, Fletcher A, Foster PJ, Pfeiffer N, Klaver CC, Hammond CJ. Prevalence of refractive error in Europe: the European Eye Epidemiology (E(3)) Consortium. Eur J Epidemiol. 2015 Apr; 30(4):305-15. PMID: 25784363; PMCID: PMC4385146.
  409. Ligthart S, de Vries PS, Uitterlinden AG, Hofman A, Franco OH, Chasman DI, Dehghan A. Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein. PLoS One. 2015; 10(3):e0118859. PMID: 25768928; PMCID: PMC4358943.
  410. Medina-Gomez C, Felix JF, Estrada K, Peters MJ, Herrera L, Kruithof CJ, Duijts L, Hofman A, van Duijn CM, Uitterlinden AG, Jaddoe VW, Rivadeneira F. Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study. Eur J Epidemiol. 2015 Apr; 30(4):317-30. PMID: 25762173; PMCID: PMC4385148.
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  412. van Leeuwen EM, Karssen LC, Deelen J, Isaacs A, Medina-Gomez C, Mbarek H, Kanterakis A, Trompet S, Postmus I, Verweij N, van Enckevort DJ, Huffman JE, White CC, Feitosa MF, Bartz TM, Manichaikul A, Joshi PK, Peloso GM, Deelen P, van Dijk F, Willemsen G, de Geus EJ, Milaneschi Y, Penninx BW, Francioli LC, Menelaou A, Pulit SL, Rivadeneira F, Hofman A, Oostra BA, Franco OH, Mateo Leach I, Beekman M, de Craen AJ, Uh HW, Trochet H, Hocking LJ, Porteous DJ, Sattar N, Packard CJ, Buckley BM, Brody JA, Bis JC, Rotter JI, Mychaleckyj JC, Campbell H, Duan Q, Lange LA, Wilson JF, Hayward C, Polasek O, Vitart V, Rudan I, Wright AF, Rich SS, Psaty BM, Borecki IB, Kearney PM, Stott DJ, Adrienne Cupples L, Jukema JW, van der Harst P, Sijbrands EJ, Hottenga JJ, Uitterlinden AG, Swertz MA, van Ommen GJ, de Bakker PI, Eline Slagboom P, Boomsma DI, Wijmenga C, van Duijn CM. Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nat Commun. 2015 Mar 09; 6:6065. PMID: 25751400; PMCID: PMC4366498.
  413. Akoudad S, Sedaghat S, Hofman A, Koudstaal PJ, van der Lugt A, Ikram MA, Vernooij MW. Kidney function and cerebral small vessel disease in the general population. Int J Stroke. 2015 Jun; 10(4):603-8. PMID: 25753173.
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  415. Verkouteren JAC, Smedinga H, Steyerberg EW, Hofman A, Nijsten T. Predicting the Risk of a Second Basal Cell Carcinoma. J Invest Dermatol. 2015 Nov; 135(11):2649-2656. PMID: 26121210.
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  416. de Keyser CE, Becker ML, Hofman A, Lous JJ, Uitterlinden AG, Visser LE, Stricker BH. The rs13064411 polymorphism in the WDR52 gene, associated with PCSK9 levels, modifies statin-induced changes in serum total and LDL cholesterol levels. Pharmacogenet Genomics. 2015 Mar; 25(3):134-42. PMID: 25602530.
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  417. Jacobs LC, Liu F, Pardo LM, Hofman A, Uitterlinden AG, Kayser M, Nijsten T. IRF4, MC1R and TYR genes are risk factors for actinic keratosis independent of skin color. Hum Mol Genet. 2015 Jun 01; 24(11):3296-303. PMID: 25724930.
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  418. Schultheiss UT, Teumer A, Medici M, Li Y, Daya N, Chaker L, Homuth G, Uitterlinden AG, Nauck M, Hofman A, Selvin E, Völzke H, Peeters RP, Köttgen A. A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations. J Clin Endocrinol Metab. 2015 May; 100(5):E799-807. PMID: 25719932; PMCID: PMC4422885 [Available on 05/01/16].
  419. Rijlaarsdam J, Stevens GW, van der Ende J, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Prevalence of DSM-IV disorders in a population-based sample of 5- to 8-year-old children: the impact of impairment criteria. Eur Child Adolesc Psychiatry. 2015 Nov; 24(11):1339-48. PMID: 25715995; PMCID: PMC4628613.
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  421. Brown ZA, Schalekamp-Timmermans S, Hofman A, Jaddoe V, Steegers E. [60-OR]: Fetal sex specific differences in maternal vascular adaptation to pregnancy. Pregnancy Hypertens. 2015 Jan; 5(1):31-2. PMID: 25787410.
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  422. Jacobs LC, Hamer MA, Gunn DA, Deelen J, Lall JS, van Heemst D, Uh HW, Hofman A, Uitterlinden AG, Griffiths CEM, Beekman M, Slagboom PE, Kayser M, Liu F, Nijsten T. A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots. J Invest Dermatol. 2015 Jul; 135(7):1735-1742. PMID: 25705849.
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  424. Lahousse L, Verlinden VJ, van der Geest JN, Joos GF, Hofman A, Stricker BH, Brusselle GG, Ikram MA. Gait patterns in COPD: the Rotterdam Study. Eur Respir J. 2015 Jul; 46(1):88-95. PMID: 25700390.
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  426. Luik AI, Zuurbier LA, Direk N, Hofman A, Van Someren EJ, Tiemeier H. 24-HOUR ACTIVITY RHYTHM AND SLEEP DISTURBANCES IN DEPRESSION AND ANXIETY: A POPULATION-BASED STUDY OF MIDDLE-AGED AND OLDER PERSONS. Depress Anxiety. 2015 Sep; 32(9):684-92. PMID: 25693731.
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  427. Voortman T, van den Hooven EH, Heijboer AC, Hofman A, Jaddoe VW, Franco OH. Vitamin D deficiency in school-age children is associated with sociodemographic and lifestyle factors. J Nutr. 2015 Apr; 145(4):791-8. PMID: 25833782.
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  430. Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Croteau-Chonka DC, Esko T, Fall T, Ferreira T, Gustafsson S, Kutalik Z, Luan J, Mägi R, Randall JC, Winkler TW, Wood AR, Workalemahu T, Faul JD, Smith JA, Zhao JH, Zhao W, Chen J, Fehrmann R, Hedman ÅK, Karjalainen J, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bolton JL, Bragg-Gresham JL, Buyske S, Demirkan A, Deng G, Ehret GB, Feenstra B, Feitosa MF, Fischer K, Goel A, Gong J, Jackson AU, Kanoni S, Kleber ME, Kristiansson K, Lim U, Lotay V, Mangino M, Leach IM, Medina-Gomez C, Medland SE, Nalls MA, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Shungin D, Stancáková A, Strawbridge RJ, Sung YJ, Tanaka T, Teumer A, Trompet S, van der Laan SW, van Setten J, Van Vliet-Ostaptchouk JV, Wang Z, Yengo L, Zhang W, Isaacs A, Albrecht E, Ärnlöv J, Arscott GM, Attwood AP, Bandinelli S, Barrett A, Bas IN, Bellis C, Bennett AJ, Berne C, Blagieva R, Blüher M, Böhringer S, Bonnycastle LL, Böttcher Y, Boyd HA, Bruinenberg M, Caspersen IH, Chen YI, Clarke R, Daw EW, de Craen AJM, Delgado G, Dimitriou M, Doney ASF, Eklund N, Estrada K, Eury E, Folkersen L, Fraser RM, Garcia ME, Geller F, Giedraitis V, Gigante B, Go AS, Golay A, Goodall AH, Gordon SD, Gorski M, Grabe HJ, Grallert H, Grammer TB, Gräßler J, Grönberg H, Groves CJ, Gusto G, Haessler J, Hall P, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heard-Costa NL, Helmer Q, Hengstenberg C, Holmen O, Hottenga JJ, James AL, Jeff JM, Johansson Å, Jolley J, Juliusdottir T, Kinnunen L, Koenig W, Koskenvuo M, Kratzer W, Laitinen J, Lamina C, Leander K, Lee NR, Lichtner P, Lind L, Lindström J, Lo KS, Lobbens S, Lorbeer R, Lu Y, Mach F, Magnusson PKE, Mahajan A, McArdle WL, McLachlan S, Menni C, Merger S, Mihailov E, Milani L, Moayyeri A, Monda KL, Morken MA, Mulas A, Müller G, Müller-Nurasyid M, Musk AW, Nagaraja R, Nöthen MM, Nolte IM, Pilz S, Rayner NW, Renstrom F, Rettig R, Ried JS, Ripke S, Robertson NR, Rose LM, Sanna S, Scharnagl H, Scholtens S, Schumacher FR, Scott WR, Seufferlein T, Shi J, Smith AV, Smolonska J, Stanton AV, Steinthorsdottir V, Stirrups K, Stringham HM, Sundström J, Swertz MA, Swift AJ, Syvänen AC, Tan ST, Tayo BO, Thorand B, Thorleifsson G, Tyrer JP, Uh HW, Vandenput L, Verhulst FC, Vermeulen SH, Verweij N, Vonk JM, Waite LL, Warren HR, Waterworth D, Weedon MN, Wilkens LR, Willenborg C, Wilsgaard T, Wojczynski MK, Wong A, Wright AF, Zhang Q, Brennan EP, Choi M, Dastani Z, Drong AW, Eriksson P, Franco-Cereceda A, Gådin JR, Gharavi AG, Goddard ME, Handsaker RE, Huang J, Karpe F, Kathiresan S, Keildson S, Kiryluk K, Kubo M, Lee JY, Liang L, Lifton RP, Ma B, McCarroll SA, McKnight AJ, Min JL, Moffatt MF, Montgomery GW, Murabito JM, Nicholson G, Nyholt DR, Okada Y, Perry JRB, Dorajoo R, Reinmaa E, Salem RM, Sandholm N, Scott RA, Stolk L, Takahashi A, Tanaka T, van 't Hooft FM, Vinkhuyzen AAE, Westra HJ, Zheng W, Zondervan KT, Heath AC, Arveiler D, Bakker SJL, Beilby J, Bergman RN, Blangero J, Bovet P, Campbell H, Caulfield MJ, Cesana G, Chakravarti A, Chasman DI, Chines PS, Collins FS, Crawford DC, Cupples LA, Cusi D, Danesh J, de Faire U, den Ruijter HM, Dominiczak AF, Erbel R, Erdmann J, Eriksson JG, Farrall M, Felix SB, Ferrannini E, Ferrières J, Ford I, Forouhi NG, Forrester T, Franco OH, Gansevoort RT, Gejman PV, Gieger C, Gottesman O, Gudnason V, Gyllensten U, Hall AS, Harris TB, Hattersley AT, Hicks AA, Hindorff LA, Hingorani AD, Hofman A, Homuth G, Hovingh GK, Humphries SE, Hunt SC, Hyppönen E, Illig T, Jacobs KB, Jarvelin MR, Jöckel KH, Johansen B, Jousilahti P, Jukema JW, Jula AM, Kaprio J, Kastelein JJP, Keinanen-Kiukaanniemi SM, Kiemeney LA, Knekt P, Kooner JS, Kooperberg C, Kovacs P, Kraja AT, Kumari M, Kuusisto J, Lakka TA, Langenberg C, Marchand LL, Lehtimäki T, Lyssenko V, Männistö S, Marette A, Matise TC, McKenzie CA, McKnight B, Moll FL, Morris AD, Morris AP, Murray JC, Nelis M, Ohlsson C, Oldehinkel AJ, Ong KK, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015 Feb 12; 518(7538):197-206. PMID: 25673413; PMCID: PMC4382211.
  431. Campos-Obando N, Kavousi M, Roeters van Lennep JE, Rivadeneira F, Hofman A, Uitterlinden AG, Franco OH, Zillikens MC. Bone health and coronary artery calcification: The Rotterdam Study. Atherosclerosis. 2015 Jul; 241(1):278-83. PMID: 25690697.
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  432. Gishti O, Gaillard R, Durmus B, Abrahamse M, van der Beek EM, Hofman A, Franco OH, de Jonge LL, Jaddoe VW. BMI, total and abdominal fat distribution, and cardiovascular risk factors in school-age children. Pediatr Res. 2015 May; 77(5):710-8. PMID: 25665058.
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  433. Verhaaren BF, Debette S, Bis JC, Smith JA, Ikram MK, Adams HH, Beecham AH, Rajan KB, Lopez LM, Barral S, van Buchem MA, van der Grond J, Smith AV, Hegenscheid K, Aggarwal NT, de Andrade M, Atkinson EJ, Beekman M, Beiser AS, Blanton SH, Boerwinkle E, Brickman AM, Bryan RN, Chauhan G, Chen CP, Chouraki V, de Craen AJ, Crivello F, Deary IJ, Deelen J, De Jager PL, Dufouil C, Elkind MS, Evans DA, Freudenberger P, Gottesman RF, Guðnason V, Habes M, Heckbert SR, Heiss G, Hilal S, Hofer E, Hofman A, Ibrahim-Verbaas CA, Knopman DS, Lewis CE, Liao J, Liewald DC, Luciano M, van der Lugt A, Martinez OO, Mayeux R, Mazoyer B, Nalls M, Nauck M, Niessen WJ, Oostra BA, Psaty BM, Rice KM, Rotter JI, von Sarnowski B, Schmidt H, Schreiner PJ, Schuur M, Sidney SS, Sigurdsson S, Slagboom PE, Stott DJ, van Swieten JC, Teumer A, Töglhofer AM, Traylor M, Trompet S, Turner ST, Tzourio C, Uh HW, Uitterlinden AG, Vernooij MW, Wang JJ, Wong TY, Wardlaw JM, Windham BG, Wittfeld K, Wolf C, Wright CB, Yang Q, Zhao W, Zijdenbos A, Jukema JW, Sacco RL, Kardia SL, Amouyel P, Mosley TH, Longstreth WT, DeCarli CC, van Duijn CM, Schmidt R, Launer LJ, Grabe HJ, Seshadri SS, Ikram MA, Fornage M. Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circ Cardiovasc Genet. 2015 Apr; 8(2):398-409. PMID: 25663218; PMCID: PMC4427240.
  434. Freak-Poli R, Mirza SS, Franco OH, Ikram MA, Hofman A, Tiemeier H. Positive affect is not associated with incidence of cardiovascular disease: a population-based study of older persons. Prev Med. 2015 May; 74:14-20. PMID: 25661731.
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  435. Reppe S, Noer A, Grimholt RM, Halldórsson BV, Medina-Gomez C, Gautvik VT, Olstad OK, Berg JP, Datta H, Estrada K, Hofman A, Uitterlinden AG, Rivadeneira F, Lyle R, Collas P, Gautvik KM. Methylation of bone SOST, its mRNA, and serum sclerostin levels correlate strongly with fracture risk in postmenopausal women. J Bone Miner Res. 2015 Feb; 30(2):249-56. PMID: 25155887.
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  436. Saeed Mirza S, Ikram MA, Hofman A, Tiemeier H. Anxiety does not predict mortality. A population-based study. World Psychiatry. 2015 Feb; 14(1):103-4. PMID: 25655167; PMCID: PMC4329906.
  437. Springelkamp H, Iglesias AI, Cuellar-Partida G, Amin N, Burdon KP, van Leeuwen EM, Gharahkhani P, Mishra A, van der Lee SJ, Hewitt AW, Rivadeneira F, Viswanathan AC, Wolfs RC, Martin NG, Ramdas WD, van Koolwijk LM, Pennell CE, Vingerling JR, Mountain JE, Uitterlinden AG, Hofman A, Mitchell P, Lemij HG, Wang JJ, Klaver CC, Mackey DA, Craig JE, van Duijn CM, MacGregor S. ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure. Hum Mol Genet. 2015 May 01; 24(9):2689-99. PMID: 25637523.
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  438. Kooijman MN, Bakker H, Franco OH, Hofman A, Taal HR, Jaddoe VW. Fetal Smoke Exposure and Kidney Outcomes in School-Aged Children. Am J Kidney Dis. 2015 Sep; 66(3):412-20. PMID: 25641064.
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  439. Cardona Cano S, Tiemeier H, Van Hoeken D, Tharner A, Jaddoe VW, Hofman A, Verhulst FC, Hoek HW. Trajectories of picky eating during childhood: A general population study. Int J Eat Disord. 2015 Sep; 48(6):570-9. PMID: 25644130.
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  440. Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L, Hidalgo B, Fox K, Huffman JE, An P, Lu Y, Rasmussen-Torvik LJ, Grarup N, Ehm MG, Li L, Baldridge AS, Stancáková A, Abrol R, Besse C, Boland A, Bork-Jensen J, Fornage M, Freitag DF, Garcia ME, Guo X, Hara K, Isaacs A, Jakobsdottir J, Lange LA, Layton JC, Li M, Hua Zhao J, Meidtner K, Morrison AC, Nalls MA, Peters MJ, Sabater-Lleal M, Schurmann C, Silveira A, Smith AV, Southam L, Stoiber MH, Strawbridge RJ, Taylor KD, Varga TV, Allin KH, Amin N, Aponte JL, Aung T, Barbieri C, Bihlmeyer NA, Boehnke M, Bombieri C, Bowden DW, Burns SM, Chen Y, Chen YD, Cheng CY, Correa A, Czajkowski J, Dehghan A, Ehret GB, Eiriksdottir G, Escher SA, Farmaki AE, Frånberg M, Gambaro G, Giulianini F, Goddard WA, Goel A, Gottesman O, Grove ML, Gustafsson S, Hai Y, Hallmans G, Heo J, Hoffmann P, Ikram MK, Jensen RA, Jørgensen ME, Jørgensen T, Karaleftheri M, Khor CC, Kirkpatrick A, Kraja AT, Kuusisto J, Lange EM, Lee IT, Lee WJ, Leong A, Liao J, Liu C, Liu Y, Lindgren CM, Linneberg A, Malerba G, Mamakou V, Marouli E, Maruthur NM, Matchan A, McKean-Cowdin R, McLeod O, Metcalf GA, Mohlke KL, Muzny DM, Ntalla I, Palmer ND, Pasko D, Peter A, Rayner NW, Renström F, Rice K, Sala CF, Sennblad B, Serafetinidis I, Smith JA, Soranzo N, Speliotes EK, Stahl EA, Stirrups K, Tentolouris N, Thanopoulou A, Torres M, Traglia M, Tsafantakis E, Javad S, Yanek LR, Zengini E, Becker DM, Bis JC, Brown JB, Cupples LA, Hansen T, Ingelsson E, Karter AJ, Lorenzo C, Mathias RA, Norris JM, Peloso GM, Sheu WH, Toniolo D, Vaidya D, Varma R, Wagenknecht LE, Boeing H, Bottinger EP, Dedoussis G, Deloukas P, Ferrannini E, Franco OH, Franks PW, Gibbs RA, Gudnason V, Hamsten A, Harris TB, Hattersley AT, Hayward C, Hofman A, Jansson JH, Langenberg C, Launer LJ, Levy D, Oostra BA, O'Donnell CJ, O'Rahilly S, Padmanabhan S, Pankow JS, Polasek O, Province MA, Rich SS, Ridker PM, Rudan I, Schulze MB, Smith BH, Uitterlinden AG, Walker M, Watkins H, Wong TY, Zeggini E, Laakso M, Borecki IB, Chasman DI, Pedersen O, Psaty BM, Tai ES, van Duijn CM, Wareham NJ, Waterworth DM, Boerwinkle E, Kao WH, Florez JC, Loos RJ, Wilson JG, Frayling TM, Siscovick DS, Dupuis J, Rotter JI, Meigs JB, Scott RA, Goodarzi MO. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nat Commun. 2015 Jan 29; 6:5897. PMID: 25631608; PMCID: PMC4311266.
  441. de Bruijn RF, Portegies ML, Leening MJ, Bos MJ, Hofman A, van der Lugt A, Niessen WJ, Vernooij MW, Franco OH, Koudstaal PJ, Ikram MA. Subclinical cardiac dysfunction increases the risk of stroke and dementia: the Rotterdam Study. Neurology. 2015 Feb 24; 84(8):833-40. PMID: 25632093.
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  442. Springelkamp H, Mishra A, Hysi PG, Gharahkhani P, Höhn R, Khor CC, Cooke Bailey JN, Luo X, Ramdas WD, Vithana E, Koh V, Yazar S, Xu L, Forward H, Kearns LS, Amin N, Iglesias AI, Sim KS, van Leeuwen EM, Demirkan A, van der Lee S, Loon SC, Rivadeneira F, Nag A, Sanfilippo PG, Schillert A, de Jong PT, Oostra BA, Uitterlinden AG, Hofman A, Zhou T, Burdon KP, Spector TD, Lackner KJ, Saw SM, Vingerling JR, Teo YY, Pasquale LR, Wolfs RC, Lemij HG, Tai ES, Jonas JB, Cheng CY, Aung T, Jansonius NM, Klaver CC, Craig JE, Young TL, Haines JL, MacGregor S, Mackey DA, Pfeiffer N, Wong TY, Wiggs JL, Hewitt AW, van Duijn CM, Hammond CJ. Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology. Genet Epidemiol. 2015 Mar; 39(3):207-16. PMID: 25631615; PMCID: PMC4480365.
  443. Noordam R, Direk N, Sitlani CM, Aarts N, Tiemeier H, Hofman A, Uitterlinden AG, Psaty BM, Stricker BH, Visser LE. Identifying genetic loci associated with antidepressant drug response with drug-gene interaction models in a population-based study. J Psychiatr Res. 2015 Mar; 62:31-7. PMID: 25649181.
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  444. Luik AI, Direk N, Zuurbier LA, Hofman A, Van Someren EJ, Tiemeier H. Sleep and 24-h activity rhythms in relation to cortisol change after a very low-dose of dexamethasone. Psychoneuroendocrinology. 2015 Mar; 53:207-16. PMID: 25635613.
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  445. Zuurbier LA, Luik AI, Leening MJ, Hofman A, Freak-Poli R, Franco OH, Stricker BH, Tiemeier H. Associations of heart failure with sleep quality: the Rotterdam Study. J Clin Sleep Med. 2015 Jan 15; 11(2):117-21. PMID: 25406270; PMCID: PMC4298768.
  446. de Goede B, Timmermans L, van Kempen BJ, van Rooij FJ, Kazemier G, Lange JF, Hofman A, Jeekel J. Risk factors for inguinal hernia in middle-aged and elderly men: results from the Rotterdam Study. Surgery. 2015 Mar; 157(3):540-6. PMID: 25596770.
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  447. Hanewinckel R, Maksimovic A, Verlinden VJ, van der Geest JN, Hofman A, van Doorn PA, Boon AJ, Tiemeier H, Ikram MA. The impact of restless legs syndrome on physical functioning in a community-dwelling population of middle-aged and elderly people. Sleep Med. 2015 Mar; 16(3):399-405. PMID: 25747142.
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  448. Blanken LM, Mous SE, Ghassabian A, Muetzel RL, Schoemaker NK, El Marroun H, van der Lugt A, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, White T. Cortical morphology in 6- to 10-year old children with autistic traits: a population-based neuroimaging study. Am J Psychiatry. 2015 May; 172(5):479-86. PMID: 25585034.
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  449. Luik AI, Zuurbier LA, Whitmore H, Hofman A, Tiemeier H. REM sleep and depressive symptoms in a population-based study of middle-aged and elderly persons. J Sleep Res. 2015 Jun; 24(3):305-8. PMID: 25581509.
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  450. Yu B, Li AH, Muzny D, Veeraraghavan N, de Vries PS, Bis JC, Musani SK, Alexander D, Morrison AC, Franco OH, Uitterlinden A, Hofman A, Dehghan A, Wilson JG, Psaty BM, Gibbs R, Wei P, Boerwinkle E. Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease. Circ Cardiovasc Genet. 2015 Apr; 8(2):351-5. PMID: 25575548; PMCID: PMC4406800 [Available on 04/01/16].
  451. Ghanbari M, Sedaghat S, de Looper HW, Hofman A, Erkeland SJ, Franco OH, Dehghan A. The association of common polymorphisms in miR-196a2 with waist to hip ratio and miR-1908 with serum lipid and glucose. Obesity (Silver Spring). 2015 Feb; 23(2):495-503. PMID: 25557604.
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  452. Baumert J, Huang J, McKnight B, Sabater-Lleal M, Steri M, Chu AY, Trompet S, Lopez LM, Fornage M, Teumer A, Tang W, Rudnicka AR, Mälarstig A, Hottenga JJ, Kavousi M, Lahti J, Tanaka T, Hayward C, Huffman JE, Morange PE, Rose LM, Basu S, Rumley A, Stott DJ, Buckley BM, de Craen AJ, Sanna S, Masala M, Biffar R, Homuth G, Silveira A, Sennblad B, Goel A, Watkins H, Müller-Nurasyid M, Rückerl R, Taylor K, Chen MH, de Geus EJ, Hofman A, Witteman JC, de Maat MP, Palotie A, Davies G, Siscovick DS, Kolcic I, Wild SH, Song J, McArdle WL, Ford I, Sattar N, Schlessinger D, Grotevendt A, Franzosi MG, Illig T, Waldenberger M, Lumley T, Tofler GH, Willemsen G, Uitterlinden AG, Rivadeneira F, Räikkönen K, Chasman DI, Folsom AR, Lowe GD, Westendorp RG, Slagboom PE, Cucca F, Wallaschofski H, Strawbridge RJ, Seedorf U, Koenig W, Bis JC, Mukamal KJ, van Dongen J, Widen E, Franco OH, Starr JM, Liu K, Ferrucci L, Polasek O, Wilson JF, Oudot-Mellakh T, Campbell H, Navarro P, Bandinelli S, Eriksson J, Boomsma DI, Dehghan A, Clarke R, Hamsten A, Boerwinkle E, Jukema JW, Naitza S, Ridker PM, Völzke H, Deary IJ, Reiner AP, Trégouët DA, O'Donnell CJ, Strachan DP, Peters A, Smith NL. No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects. PLoS One. 2014; 9(12):e111156. PMID: 25551457; PMCID: PMC4281156.
  453. Kruithof CJ, Kooijman MN, van Duijn CM, Franco OH, de Jongste JC, Klaver CC, Mackenbach JP, Moll HA, Raat H, Rings EH, Rivadeneira F, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Wolvius EB, Hofman A, Jaddoe VW. The Generation R Study: Biobank update 2015. Eur J Epidemiol. 2014 Dec; 29(12):911-27. PMID: 25527369.
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  454. Steenweg-de Graaff JC, Tiemeier H, Basten MG, Rijlaarsdam J, Demmelmair H, Koletzko B, Hofman A, Jaddoe VW, Verhulst FC, Roza SJ. Maternal LC-PUFA status during pregnancy and child problem behavior: the Generation R Study. Pediatr Res. 2015 Mar; 77(3):489-97. PMID: 25521921.
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  455. Spaan S, Pronk A, Koch HM, Jusko TA, Jaddoe VW, Shaw PA, Tiemeier HM, Hofman A, Pierik FH, Longnecker MP. Reliability of concentrations of organophosphate pesticide metabolites in serial urine specimens from pregnancy in the Generation R Study. J Expo Sci Environ Epidemiol. 2015 May; 25(3):286-94. PMID: 25515376; PMCID: PMC4409451.
  456. Wijtzes AI, Jansen W, Bouthoorn SH, Pot N, Hofman A, Jaddoe VW, Raat H. Social inequalities in young children's sports participation and outdoor play. Int J Behav Nutr Phys Act. 2014 Dec 16; 11:155. PMID: 25510552; PMCID: PMC4272790.
  457. Dhana K, Ikram MA, Hofman A, Franco OH, Kavousi M. Anthropometric measures in cardiovascular disease prediction: comparison of laboratory-based versus non-laboratory-based model. Heart. 2015 Mar; 101(5):377-83. PMID: 25502814.
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  458. Sajjad A, Mirza SS, Portegies ML, Bos MJ, Hofman A, Koudstaal PJ, Tiemeier H, Ikram MA. Subjective memory complaints and the risk of stroke. Stroke. 2015 Jan; 46(1):170-5. PMID: 25503545.
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  459. Parmar P, Krishnamurthi R, Ikram MA, Hofman A, Mirza SS, Varakin Y, Kravchenko M, Piradov M, Thrift AG, Norrving B, Wang W, Mandal DK, Barker-Collo S, Sahathevan R, Davis S, Saposnik G, Kivipelto M, Sindi S, Bornstein NM, Giroud M, Béjot Y, Brainin M, Poulton R, Narayan KM, Correia M, Freire A, Kokubo Y, Wiebers D, Mensah G, BinDhim NF, Barber PA, Pandian JD, Hankey GJ, Mehndiratta MM, Azhagammal S, Ibrahim NM, Abbott M, Rush E, Hume P, Hussein T, Bhattacharjee R, Purohit M, Feigin VL. The Stroke Riskometer(TM) App: validation of a data collection tool and stroke risk predictor. Int J Stroke. 2015 Feb; 10(2):231-44. PMID: 25491651; PMCID: PMC4335600.
  460. Voortman T, Kiefte-de Jong JC, Geelen A, Villamor E, Moll HA, de Jongste JC, Raat H, Hofman A, Jaddoe VW, Franco OH, van den Hooven EH. The development of a diet quality score for preschool children and its validation and determinants in the Generation R Study. J Nutr. 2015 Feb; 145(2):306-14. PMID: 25644352.
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  461. Gorski M, Tin A, Garnaas M, McMahon GM, Chu AY, Tayo BO, Pattaro C, Teumer A, Chasman DI, Chalmers J, Hamet P, Tremblay J, Woodward M, Aspelund T, Eiriksdottir G, Gudnason V, Harris TB, Launer LJ, Smith AV, Mitchell BD, O'Connell JR, Shuldiner AR, Coresh J, Li M, Freudenberger P, Hofer E, Schmidt H, Schmidt R, Holliday EG, Mitchell P, Wang JJ, de Boer IH, Li G, Siscovick DS, Kutalik Z, Corre T, Vollenweider P, Waeber G, Gupta J, Kanetsky PA, Hwang SJ, Olden M, Yang Q, de Andrade M, Atkinson EJ, Kardia SL, Turner ST, Stafford JM, Ding J, Liu Y, Barlassina C, Cusi D, Salvi E, Staessen JA, Ridker PM, Grallert H, Meisinger C, Müller-Nurasyid M, Krämer BK, Kramer H, Rosas SE, Nolte IM, Penninx BW, Snieder H, Fabiola Del Greco M, Franke A, Nöthlings U, Lieb W, Bakker SJ, Gansevoort RT, van der Harst P, Dehghan A, Franco OH, Hofman A, Rivadeneira F, Sedaghat S, Uitterlinden AG, Coassin S, Haun M, Kollerits B, Kronenberg F, Paulweber B, Aumann N, Endlich K, Pietzner M, Völker U, Rettig R, Chouraki V, Helmer C, Lambert JC, Metzger M, Stengel B, Lehtimäki T, Lyytikäinen LP, Raitakari O, Johnson A, Parsa A, Bochud M, Heid IM, Goessling W, Köttgen A, Kao WH, Fox CS, Böger CA. Genome-wide association study of kidney function decline in individuals of European descent. Kidney Int. 2015 May; 87(5):1017-29. PMID: 25493955; PMCID: PMC4425568.
  462. Luijk MP, Sonnenschein-van der Voort AM, Mileva-Seitz VR, Jansen PW, Verhulst FC, Hofman A, Jaddoe VW, de Jongste JC, van IJzendoorn MH, Duijts L, Tiemeier H. Is parent-child bed-sharing a risk for wheezing and asthma in early childhood? Eur Respir J. 2015 Mar; 45(3):661-9. PMID: 25504998.
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  463. Portegies ML, Selwaness M, Hofman A, Koudstaal PJ, Vernooij MW, Ikram MA. Left-sided strokes are more often recognized than right-sided strokes: the Rotterdam study. Stroke. 2015 Jan; 46(1):252-4. PMID: 25492906.
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  464. Zuurbier LA, Luik AI, Hofman A, Franco OH, Van Someren EJ, Tiemeier H. Fragmentation and stability of circadian activity rhythms predict mortality: the Rotterdam study. Am J Epidemiol. 2015 Jan 01; 181(1):54-63. PMID: 25491893.
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  465. Levin D, Bell S, Sund R, Hartikainen SA, Tuomilehto J, Pukkala E, Keskimäki I, Badrick E, Renehan AG, Buchan IE, Bowker SL, Minhas-Sandhu JK, Zafari Z, Marra C, Johnson JA, Stricker BH, Uitterlinden AG, Hofman A, Ruiter R, de Keyser CE, MacDonald TM, Wild SH, McKeigue PM, Colhoun HM. Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis. Diabetologia. 2015 Mar; 58(3):493-504. PMID: 25481707.
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  466. Medici M, Korevaar TI, Schalekamp-Timmermans S, Gaillard R, de Rijke YB, Visser WE, Visser W, de Muinck Keizer-Schrama SM, Hofman A, Hooijkaas H, Bongers-Schokking JJ, Tiemeier H, Jaddoe VW, Visser TJ, Peeters RP, Steegers EA. Maternal early-pregnancy thyroid function is associated with subsequent hypertensive disorders of pregnancy: the generation R study. J Clin Endocrinol Metab. 2014 Dec; 99(12):E2591-8. PMID: 25157540.
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  467. Heppe DH, Medina-Gomez C, de Jongste JC, Raat H, Steegers EA, Hofman A, Rivadeneira F, Jaddoe VW. Fetal and childhood growth patterns associated with bone mass in school-age children: the Generation R Study. J Bone Miner Res. 2014 Dec; 29(12):2584-93. PMID: 24935163.
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  468. van Mil NH, Bouwland-Both MI, Stolk L, Verbiest MM, Hofman A, Jaddoe VW, Verhulst FC, Eilers PH, Uitterlinden AG, Steegers EA, Tiemeier H, Steegers-Theunissen RP. Determinants of maternal pregnancy one-carbon metabolism and newborn human DNA methylation profiles. Reproduction. 2014 Dec; 148(6):581-92. PMID: 25392189.
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  469. Ghanbari M, de Vries PS, de Looper H, Peters MJ, Schurmann C, Yaghootkar H, Dörr M, Frayling TM, Uitterlinden AG, Hofman A, van Meurs JB, Erkeland SJ, Franco OH, Dehghan A. A genetic variant in the seed region of miR-4513 shows pleiotropic effects on lipid and glucose homeostasis, blood pressure, and coronary artery disease. Hum Mutat. 2014 Dec; 35(12):1524-31. PMID: 25256095.
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  470. O'Doherty MG, Jørgensen T, Borglykke A, Brenner H, Schöttker B, Wilsgaard T, Siganos G, Kavousi M, Hughes M, Müezzinler A, Holleczek B, Franco OH, Hofman A, Boffetta P, Trichopoulou A, Kee F. Repeated measures of body mass index and C-reactive protein in relation to all-cause mortality and cardiovascular disease: results from the consortium on health and ageing network of cohorts in Europe and the United States (CHANCES). Eur J Epidemiol. 2014 Dec; 29(12):887-97. PMID: 25421782.
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  471. Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, Grabe HJ, Smith JA, Priebe L, Yu L, Karbalai N, Hayward C, Wilson JF, Campbell H, Petrovic K, Fornage M, Chauhan G, Yeo R, Boxall R, Becker J, Stegle O, Mather KA, Chouraki V, Sun Q, Rose LM, Resnick S, Oldmeadow C, Kirin M, Wright AF, Jonsdottir MK, Au R, Becker A, Amin N, Nalls MA, Turner ST, Kardia SL, Oostra B, Windham G, Coker LH, Zhao W, Knopman DS, Heiss G, Griswold ME, Gottesman RF, Vitart V, Hastie ND, Zgaga L, Rudan I, Polasek O, Holliday EG, Schofield P, Choi SH, Tanaka T, An Y, Perry RT, Kennedy RE, Sale MM, Wang J, Wadley VG, Liewald DC, Ridker PM, Gow AJ, Pattie A, Starr JM, Porteous D, Liu X, Thomson R, Armstrong NJ, Eiriksdottir G, Assareh AA, Kochan NA, Widen E, Palotie A, Hsieh YC, Eriksson JG, Vogler C, van Swieten JC, Shulman JM, Beiser A, Rotter J, Schmidt CO, Hoffmann W, Nöthen MM, Ferrucci L, Attia J, Uitterlinden AG, Amouyel P, Dartigues JF, Amieva H, Räikkönen K, Garcia M, Wolf PA, Hofman A, Longstreth WT, Psaty BM, Boerwinkle E, DeJager PL, Sachdev PS, Schmidt R, Breteler MM, Teumer A, Lopez OL, Cichon S, Chasman DI, Grodstein F, Müller-Myhsok B, Tzourio C, Papassotiropoulos A, Bennett DA, Ikram MA, Deary IJ, van Duijn CM, Launer L, Fitzpatrick AL, Seshadri S, Mosley TH. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77(8):749-63. PMID: 25648963; PMCID: PMC4513651.
  472. Willeit P, Thompson SG, Agewall S, Bergström G, Bickel H, Catapano AL, Chien KL, de Groot E, Empana JP, Etgen T, Franco OH, Iglseder B, Johnsen SH, Kavousi M, Lind L, Liu J, Mathiesen EB, Norata GD, Olsen MH, Papagianni A, Poppert H, Price JF, Sacco RL, Yanez DN, Zhao D, Schminke U, Bülbül A, Polak JF, Sitzer M, Hofman A, Grigore L, Dörr M, Su TC, Ducimetière P, Xie W, Ronkainen K, Kiechl S, Rundek T, Robertson C, Fagerberg B, Bokemark L, Steinmetz H, Ikram MA, Völzke H, Lin HJ, Plichart M, Tuomainen TP, Desvarieux M, McLachlan S, Schmidt C, Kauhanen J, Willeit J, Lorenz MW, Sander D. Inflammatory markers and extent and progression of early atherosclerosis: Meta-analysis of individual-participant-data from 20 prospective studies of the PROG-IMT collaboration. Eur J Prev Cardiol. 2016 Jan; 23(2):194-205. PMID: 25416041; PMCID: PMC4544641.
  473. Springelkamp H, Lee K, Wolfs RC, Buitendijk GH, Ramdas WD, Hofman A, Vingerling JR, Klaver CC, Abràmoff MD, Jansonius NM. Population-based evaluation of retinal nerve fiber layer, retinal ganglion cell layer, and inner plexiform layer as a diagnostic tool for glaucoma. Invest Ophthalmol Vis Sci. 2014 Nov 20; 55(12):8428-38. PMID: 25414193; PMCID: PMC4280090.
  474. Leening MJ, Ferket BS, Steyerberg EW, Kavousi M, Deckers JW, Nieboer D, Heeringa J, Portegies ML, Hofman A, Ikram MA, Hunink MG, Franco OH, Stricker BH, Witteman JC, Roos-Hesselink JW. Sex differences in lifetime risk and first manifestation of cardiovascular disease: prospective population based cohort study. BMJ. 2014 Nov 17; 349:g5992. PMID: 25403476; PMCID: PMC4233917.
  475. Mileva-Seitz VR, Ghassabian A, Bakermans-Kranenburg MJ, van den Brink JD, Linting M, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, van IJzendoorn MH. Are boys more sensitive to sensitivity? Parenting and executive function in preschoolers. J Exp Child Psychol. 2015 Feb; 130:193-208. PMID: 25462041.
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  476. de Barse LM, Tharner A, Micali N, Jaddoe VV, Hofman A, Verhulst FC, Franco OH, Tiemeier H, Jansen PW. Does maternal history of eating disorders predict mothers' feeding practices and preschoolers' emotional eating? Appetite. 2015 Feb; 85:1-7. PMID: 25450896.
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  477. Li Q, Wojciechowski R, Simpson CL, Hysi PG, Verhoeven VJ, Ikram MK, Höhn R, Vitart V, Hewitt AW, Oexle K, Mäkelä KM, MacGregor S, Pirastu M, Fan Q, Cheng CY, St Pourcain B, McMahon G, Kemp JP, Northstone K, Rahi JS, Cumberland PM, Martin NG, Sanfilippo PG, Lu Y, Wang YX, Hayward C, Polašek O, Campbell H, Bencic G, Wright AF, Wedenoja J, Zeller T, Schillert A, Mirshahi A, Lackner K, Yip SP, Yap MK, Ried JS, Gieger C, Murgia F, Wilson JF, Fleck B, Yazar S, Vingerling JR, Hofman A, Uitterlinden A, Rivadeneira F, Amin N, Karssen L, Oostra BA, Zhou X, Teo YY, Tai ES, Vithana E, Barathi V, Zheng Y, Siantar RG, Neelam K, Shin Y, Lam J, Yonova-Doing E, Venturini C, Hosseini SM, Wong HS, Lehtimäki T, Kähönen M, Raitakari O, Timpson NJ, Evans DM, Khor CC, Aung T, Young TL, Mitchell P, Klein B, van Duijn CM, Meitinger T, Jonas JB, Baird PN, Mackey DA, Wong TY, Saw SM, Pärssinen O, Stambolian D, Hammond CJ, Klaver CC, Williams C, Paterson AD, Bailey-Wilson JE, Guggenheim JA. Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium. Hum Genet. 2015 Feb; 134(2):131-46. PMID: 25367360; PMCID: PMC4291519.
  478. Tharner A, Jansen PW, Kiefte-de Jong JC, Moll HA, Hofman A, Jaddoe VW, Tiemeier H, Franco OH. Bidirectional associations between fussy eating and functional constipation in preschool children. J Pediatr. 2015 Jan; 166(1):91-6. PMID: 25443999.
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  479. Postmus I, Trompet S, Deshmukh HA, Barnes MR, Li X, Warren HR, Chasman DI, Zhou K, Arsenault BJ, Donnelly LA, Wiggins KL, Avery CL, Griffin P, Feng Q, Taylor KD, Li G, Evans DS, Smith AV, de Keyser CE, Johnson AD, de Craen AJ, Stott DJ, Buckley BM, Ford I, Westendorp RG, Slagboom PE, Sattar N, Munroe PB, Sever P, Poulter N, Stanton A, Shields DC, O'Brien E, Shaw-Hawkins S, Chen YD, Nickerson DA, Smith JD, Dubé MP, Boekholdt SM, Hovingh GK, Kastelein JJ, McKeigue PM, Betteridge J, Neil A, Durrington PN, Doney A, Carr F, Morris A, McCarthy MI, Groop L, Ahlqvist E, Bis JC, Rice K, Smith NL, Lumley T, Whitsel EA, Stürmer T, Boerwinkle E, Ngwa JS, O'Donnell CJ, Vasan RS, Wei WQ, Wilke RA, Liu CT, Sun F, Guo X, Heckbert SR, Post W, Sotoodehnia N, Arnold AM, Stafford JM, Ding J, Herrington DM, Kritchevsky SB, Eiriksdottir G, Launer LJ, Harris TB, Chu AY, Giulianini F, MacFadyen JG, Barratt BJ, Nyberg F, Stricker BH, Uitterlinden AG, Hofman A, Rivadeneira F, Emilsson V, Franco OH, Ridker PM, Gudnason V, Liu Y, Denny JC, Ballantyne CM, Rotter JI, Adrienne Cupples L, Psaty BM, Palmer CN, Tardif JC, Colhoun HM, Hitman G, Krauss RM, Wouter Jukema J, Caulfield MJ. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun. 2014 Oct 28; 5:5068. PMID: 25350695; PMCID: PMC4220464.
  480. Bouthoorn SH, Silva LM, Murray SE, Steegers EA, Jaddoe VW, Moll H, Hofman A, Mackenbach JP, Raat H. Low-educated women have an increased risk of gestational diabetes mellitus: the Generation R Study. Acta Diabetol. 2015 Jun; 52(3):445-52. PMID: 25344768.
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  481. Ligthart S, Sedaghat S, Ikram MA, Hofman A, Franco OH, Dehghan A. EN-RAGE: a novel inflammatory marker for incident coronary heart disease. Arterioscler Thromb Vasc Biol. 2014 Dec; 34(12):2695-9. PMID: 25341801.
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  482. van Leeuwen EM, Smouter FA, Kam-Thong T, Karbalai N, Smith AV, Harris TB, Launer LJ, Sitlani CM, Li G, Brody JA, Bis JC, White CC, Jaiswal A, Oostra BA, Hofman A, Rivadeneira F, Uitterlinden AG, Boerwinkle E, Ballantyne CM, Gudnason V, Psaty BM, Cupples LA, Järvelin MR, Ripatti S, Isaacs A, Müller-Myhsok B, Karssen LC, van Duijn CM. The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels. PLoS One. 2014; 9(10):e109290. PMID: 25329471; PMCID: PMC4203717.
  483. Pantavos A, Ruiter R, Feskens EF, de Keyser CE, Hofman A, Stricker BH, Franco OH, Kiefte-de Jong JC. Total dietary antioxidant capacity, individual antioxidant intake and breast cancer risk: the Rotterdam Study. Int J Cancer. 2015 May 01; 136(9):2178-86. PMID: 25284450.
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  484. Akoudad S, Darweesh SK, Leening MJ, Koudstaal PJ, Hofman A, van der Lugt A, Stricker BH, Ikram MA, Vernooij MW. Use of coumarin anticoagulants and cerebral microbleeds in the general population. Stroke. 2014 Nov; 45(11):3436-9. PMID: 25316276.
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  485. Praagman J, Franco OH, Ikram MA, Soedamah-Muthu SS, Engberink MF, van Rooij FJ, Hofman A, Geleijnse JM. Dairy products and the risk of stroke and coronary heart disease: the Rotterdam Study. Eur J Nutr. 2015 Sep; 54(6):981-90. PMID: 25296885.
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  486. Plompen EP, Hansen BE, Schouten JN, Darwish Murad S, Loth DW, Brouwer WP, Isaacs A, Taimr P, Hofman A, van Duijn CM, Uitterlinden AG, Stricker BH, Leebeek FW, Janssen HL. Interferon gamma receptor 2 gene variants are associated with liver fibrosis in the general population: the Rotterdam Study. Gut. 2015 Apr; 64(4):692-4. PMID: 25301852.
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  489. van der Valk RJ, Kreiner-Møller E, Kooijman MN, Guxens M, Stergiakouli E, Sääf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Körner A, Thiering E, Curtin JA, Myhre R, Huikari V, Joro R, Kerkhof M, Warrington NM, Pitkänen N, Ntalla I, Horikoshi M, Veijola R, Freathy RM, Teo YY, Barton SJ, Evans DM, Kemp JP, St Pourcain B, Ring SM, Davey Smith G, Bergström A, Kull I, Hakonarson H, Mentch FD, Bisgaard H, Chawes B, Stokholm J, Waage J, Eriksen P, Sevelsted A, Melbye M, van Duijn CM, Medina-Gomez C, Hofman A, de Jongste JC, Taal HR, Uitterlinden AG, Armstrong LL, Eriksson J, Palotie A, Bustamante M, Estivill X, Gonzalez JR, Llop S, Kiess W, Mahajan A, Flexeder C, Tiesler CM, Murray CS, Simpson A, Magnus P, Sengpiel V, Hartikainen AL, Keinanen-Kiukaanniemi S, Lewin A, Da Silva Couto Alves A, Blakemore AI, Buxton JL, Kaakinen M, Rodriguez A, Sebert S, Vaarasmaki M, Lakka T, Lindi V, Gehring U, Postma DS, Ang W, Newnham JP, Lyytikäinen LP, Pahkala K, Raitakari OT, Panoutsopoulou K, Zeggini E, Boomsma DI, Groen-Blokhuis M, Ilonen J, Franke L, Hirschhorn JN, Pers TH, Liang L, Huang J, Hocher B, Knip M, Saw SM, Holloway JW, Melén E, Grant SF, Feenstra B, Lowe WL, Widén E, Sergeyev E, Grallert H, Custovic A, Jacobsson B, Jarvelin MR, Atalay M, Koppelman GH, Pennell CE, Niinikoski H, Dedoussis GV, Mccarthy MI, Frayling TM, Sunyer J, Timpson NJ, Rivadeneira F, Bønnelykke K, Jaddoe VW. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet. 2015 Feb 15; 24(4):1155-68. PMID: 25281659; PMCID: PMC4447786.
  490. Loehrer E, Vernooij MW, van der Lugt A, Hofman A, Ikram MA. Migraine and cerebral blood flow in the general population. Cephalalgia. 2015 Feb; 35(2):190-8. PMID: 25281221.
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  491. Gishti O, Kruithof CJ, Felix JF, Raat H, Hofman A, Duijts L, Gaillard R, Jaddoe VW. Ethnic disparities in general and abdominal adiposity at school age: a multiethnic population-based cohort study in the Netherlands. Ann Nutr Metab. 2014; 64(3-4):208-17. PMID: 25300262.
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  492. Hoogendam YY, van der Geest JN, Niessen WJ, van der Lugt A, Hofman A, Vernooij MW, Ikram MA. The role of cerebellar volume in cognition in the general elderly population. Alzheimer Dis Assoc Disord. 2014 Oct-Dec; 28(4):352-7. PMID: 24577204.
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  493. Rodenburg EM, Visser LE, Hoorn EJ, Ruiter R, Lous JJ, Hofman A, Uitterlinden AG, Stricker BH. Thiazides and the risk of hypokalemia in the general population. J Hypertens. 2014 Oct; 32(10):2092-7; discussion 2097. PMID: 25105457.
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  494. Niemeijer MN, van den Berg ME, Leening MJ, Hofman A, Franco OH, Deckers JW, Heeringa J, Rijnbeek PR, Stricker BH, Eijgelsheim M. Declining incidence of sudden cardiac death from 1990-2010 in a general middle-aged and elderly population: The Rotterdam Study. Heart Rhythm. 2015 Jan; 12(1):123-9. PMID: 25277989.
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  495. Hoogendam YY, van der Lijn F, Vernooij MW, Hofman A, Niessen WJ, van der Lugt A, Ikram MA, van der Geest JN. Older age relates to worsening of fine motor skills: a population-based study of middle-aged and elderly persons. Front Aging Neurosci. 2014; 6:259. PMID: 25309436; PMCID: PMC4174769.
  496. Windhorst DA, Mileva-Seitz VR, Linting M, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H, van IJzendoorn MH, Bakermans-Kranenburg MJ. Differential susceptibility in a developmental perspective: DRD4 and maternal sensitivity predicting externalizing behavior. Dev Psychobiol. 2015 Jan; 57(1):35-49. PMID: 25251423.
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  497. Jansen MA, Kiefte-de Jong JC, Gaillard R, Escher JC, Hofman A, Jaddoe VW, Hooijkaas H, Moll HA. Growth trajectories and bone mineral density in anti-tissue transglutaminase antibody-positive children: the Generation R Study. Clin Gastroenterol Hepatol. 2015 May; 13(5):913-20.e5. PMID: 25245626.
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  498. Springelkamp H, Höhn R, Mishra A, Hysi PG, Khor CC, Loomis SJ, Bailey JN, Gibson J, Thorleifsson G, Janssen SF, Luo X, Ramdas WD, Vithana E, Nongpiur ME, Montgomery GW, Xu L, Mountain JE, Gharahkhani P, Lu Y, Amin N, Karssen LC, Sim KS, van Leeuwen EM, Iglesias AI, Verhoeven VJ, Hauser MA, Loon SC, Despriet DD, Nag A, Venturini C, Sanfilippo PG, Schillert A, Kang JH, Landers J, Jonasson F, Cree AJ, van Koolwijk LM, Rivadeneira F, Souzeau E, Jonsson V, Menon G, Weinreb RN, de Jong PT, Oostra BA, Uitterlinden AG, Hofman A, Ennis S, Thorsteinsdottir U, Burdon KP, Spector TD, Mirshahi A, Saw SM, Vingerling JR, Teo YY, Haines JL, Wolfs RC, Lemij HG, Tai ES, Jansonius NM, Jonas JB, Cheng CY, Aung T, Viswanathan AC, Klaver CC, Craig JE, Macgregor S, Mackey DA, Lotery AJ, Stefansson K, Bergen AA, Young TL, Wiggs JL, Pfeiffer N, Wong TY, Pasquale LR, Hewitt AW, van Duijn CM, Hammond CJ. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. Nat Commun. 2014 Sep 22; 5:4883. PMID: 25241763; PMCID: PMC4199103.
  499. Verlinden VJ, van der Geest JN, Heeringa J, Hofman A, Ikram MA. Gait shows a sex-specific pattern of associations with daily functioning in a community-dwelling population of older people. Gait Posture. 2015 Jan; 41(1):119-24. PMID: 25278463.
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  500. Simpson CL, Wojciechowski R, Oexle K, Murgia F, Portas L, Li X, Verhoeven VJ, Vitart V, Schache M, Hosseini SM, Hysi PG, Raffel LJ, Cotch MF, Chew E, Klein BE, Klein R, Wong TY, van Duijn CM, Mitchell P, Saw SM, Fossarello M, Wang JJ, Polašek O, Campbell H, Rudan I, Oostra BA, Uitterlinden AG, Hofman A, Rivadeneira F, Amin N, Karssen LC, Vingerling JR, Döring A, Bettecken T, Bencic G, Gieger C, Wichmann HE, Wilson JF, Venturini C, Fleck B, Cumberland PM, Rahi JS, Hammond CJ, Hayward C, Wright AF, Paterson AD, Baird PN, Klaver CC, Rotter JI, Pirastu M, Meitinger T, Bailey-Wilson JE, Stambolian D. Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci. PLoS One. 2014; 9(9):e107110. PMID: 25233373; PMCID: PMC4169415.
  501. Vojinovic D, Adams HH, van der Lee SJ, Ibrahim-Verbaas CA, Brouwer R, van den Hout MC, Oole E, van Rooij J, Uitterlinden A, Hofman A, van IJcken WF, Aartsma-Rus A, van Ommen GB, Ikram MA, van Duijn CM, Amin N. The dystrophin gene and cognitive function in the general population. Eur J Hum Genet. 2015 Jun; 23(6):837-43. PMID: 25227141; PMCID: PMC4795046.
  502. Pappa I, Mileva-Seitz VR, Szekely E, Verhulst FC, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Tiemeier H, van IJzendoorn MH. DRD4 VNTRs, observed stranger fear in preschoolers and later ADHD symptoms. Psychiatry Res. 2014 Dec 30; 220(3):982-6. PMID: 25262643.
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  503. Selwaness M, van den Bouwhuijsen Q, van Onkelen RS, Hofman A, Franco OH, van der Lugt A, Wentzel JJ, Vernooij M. Atherosclerotic plaque in the left carotid artery is more vulnerable than in the right. Stroke. 2014 Nov; 45(11):3226-30. PMID: 25228259.
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  504. St Pourcain B, Cents RA, Whitehouse AJ, Haworth CM, Davis OS, O'Reilly PF, Roulstone S, Wren Y, Ang QW, Velders FP, Evans DM, Kemp JP, Warrington NM, Miller L, Timpson NJ, Ring SM, Verhulst FC, Hofman A, Rivadeneira F, Meaburn EL, Price TS, Dale PS, Pillas D, Yliherva A, Rodriguez A, Golding J, Jaddoe VW, Jarvelin MR, Plomin R, Pennell CE, Tiemeier H, Davey Smith G. Common variation near ROBO2 is associated with expressive vocabulary in infancy. Nat Commun. 2014 Sep 16; 5:4831. PMID: 25226531; PMCID: PMC4175587.
  505. de Keyser CE, Leening MJ, Romio SA, Jukema JW, Hofman A, Ikram MA, Franco OH, Stijnen T, Stricker BH. Comparing a marginal structural model with a Cox proportional hazard model to estimate the effect of time-dependent drug use in observational studies: statin use for primary prevention of cardiovascular disease as an example from the Rotterdam Study. Eur J Epidemiol. 2014 Nov; 29(11):841-50. PMID: 25213404.
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  506. de Groot M, Ikram MA, Akoudad S, Krestin GP, Hofman A, van der Lugt A, Niessen WJ, Vernooij MW. Tract-specific white matter degeneration in aging: the Rotterdam Study. Alzheimers Dement. 2015 Mar; 11(3):321-30. PMID: 25217294.
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  507. Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM. GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. J Gerontol A Biol Sci Med Sci. 2015 Jan; 70(1):110-8. PMID: 25199915; PMCID: PMC4296168.
  508. Verhoeven VJ, Wong KT, Buitendijk GH, Hofman A, Vingerling JR, Klaver CC. Visual consequences of refractive errors in the general population. Ophthalmology. 2015 Jan; 122(1):101-9. PMID: 25208857.
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  509. Jansen PW, Tharner A, van der Ende J, Wake M, Raat H, Hofman A, Verhulst FC, van Ijzendoorn MH, Jaddoe VW, Tiemeier H. Feeding practices and child weight: is the association bidirectional in preschool children? Am J Clin Nutr. 2014 Nov; 100(5):1329-36. PMID: 25332330.
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  510. Chaker L, Baumgartner C, Ikram MA, Dehghan A, Medici M, Visser WE, Hofman A, Rodondi N, Peeters RP, Franco OH. Subclinical thyroid dysfunction and the risk of stroke: a systematic review and meta-analysis. Eur J Epidemiol. 2014 Nov; 29(11):791-800. PMID: 25179793.
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  511. Sedaghat S, Pazoki R, Uitterlinden AG, Hofman A, Stricker BH, Ikram MA, Franco OH, Dehghan A. Association of uric acid genetic risk score with blood pressure: the Rotterdam study. Hypertension. 2014 Nov; 64(5):1061-6. PMID: 25185132.
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  512. Jansen PW, Verlinden M, Dommisse-van Berkel A, Mieloo CL, Raat H, Hofman A, Jaddoe VW, Verhulst FC, Jansen W, Tiemeier H. Teacher and peer reports of overweight and bullying among young primary school children. Pediatrics. 2014 Sep; 134(3):473-80. PMID: 25157018.
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  513. de Kruijf M, Kerkhof HJ, Peters MJ, Bierma-Zeinstra S, Hofman A, Uitterlinden AG, Huggen FJ, van Meurs JB. Finger length pattern as a biomarker for osteoarthritis and chronic joint pain: a population-based study and meta-analysis after systematic review. Arthritis Care Res (Hoboken). 2014 Sep; 66(9):1337-43. PMID: 24623639.
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  514. Hysi PG, Cheng CY, Springelkamp H, Macgregor S, Bailey JNC, Wojciechowski R, Vitart V, Nag A, Hewitt AW, Höhn R, Venturini C, Mirshahi A, Ramdas WD, Thorleifsson G, Vithana E, Khor CC, Stefansson AB, Liao J, Haines JL, Amin N, Wang YX, Wild PS, Ozel AB, Li JZ, Fleck BW, Zeller T, Staffieri SE, Teo YY, Cuellar-Partida G, Luo X, Allingham RR, Richards JE, Senft A, Karssen LC, Zheng Y, Bellenguez C, Xu L, Iglesias AI, Wilson JF, Kang JH, van Leeuwen EM, Jonsson V, Thorsteinsdottir U, Despriet DDG, Ennis S, Moroi SE, Martin NG, Jansonius NM, Yazar S, Tai ES, Amouyel P, Kirwan J, van Koolwijk LME, Hauser MA, Jonasson F, Leo P, Loomis SJ, Fogarty R, Rivadeneira F, Kearns L, Lackner KJ, de Jong PTVM, Simpson CL, Pennell CE, Oostra BA, Uitterlinden AG, Saw SM, Lotery AJ, Bailey-Wilson JE, Hofman A, Vingerling JR, Maubaret C, Pfeiffer N, Wolfs RCW, Lemij HG, Young TL, Pasquale LR, Delcourt C, Spector TD, Klaver CCW, Small KS, Burdon KP, Stefansson K, Wong TY, Viswanathan A, Mackey DA, Craig JE, Wiggs JL, van Duijn CM, Hammond CJ, Aung T. Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma. Nat Genet. 2014 Oct; 46(10):1126-1130. PMID: 25173106; PMCID: PMC4177225.
  515. den Hollander WJ, Holster IL, van Gilst B, van Vuuren AJ, Jaddoe VW, Hofman A, Perez-Perez GI, Kuipers EJ, Moll HA, Blaser MJ. Intergenerational reduction in Helicobacter pylori prevalence is similar between different ethnic groups living in a Western city. Gut. 2015 Aug; 64(8):1200-8. PMID: 25192563; PMCID: PMC4492887.
  516. Mirza SS, Tiemeier H, de Bruijn RF, Hofman A, Franco OH, Kiefte-de Jong J, Koudstaal PJ, Ikram MA. Coffee consumption and incident dementia. Eur J Epidemiol. 2014 Oct; 29(10):735-41. PMID: 25154552.
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  517. Saridjan NS, Velders FP, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. The longitudinal association of the diurnal cortisol rhythm with internalizing and externalizing problems in pre-schoolers. The Generation R Study. Psychoneuroendocrinology. 2014 Dec; 50:118-29. PMID: 25202831.
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  518. Buitendijk GH, Amin N, Hofman A, van Duijn CM, Vingerling JR, Klaver CC. Direct-to-consumer personal genome testing for age-related macular degeneration. Invest Ophthalmol Vis Sci. 2014 Aug 21; 55(10):6167-74. PMID: 25146986.
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  519. Sedaghat S, Dawkins Arce FG, Verwoert GC, Hofman A, Ikram MA, Franco OH, Dehghan A, Witteman JC, Mattace-Raso F. Association of renal function with vascular stiffness in older adults: the Rotterdam study. Age Ageing. 2014 Nov; 43(6):827-33. PMID: 25146410.
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  520. Bos D, Vernooij MW, de Bruijn RF, Koudstaal PJ, Hofman A, Franco OH, van der Lugt A, Ikram MA. Atherosclerotic calcification is related to a higher risk of dementia and cognitive decline. Alzheimers Dement. 2015 Jun; 11(6):639-47.e1. PMID: 25150731.
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  521. Wijtzes AI, Bouthoorn SH, Jansen W, Franco OH, Hofman A, Jaddoe VW, Raat H. Sedentary behaviors, physical activity behaviors, and body fat in 6-year-old children: the Generation R Study. Int J Behav Nutr Phys Act. 2014; 11:96. PMID: 25927189.
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  522. Wijtzes AI, Bouthoorn SH, Jansen W, Franco OH, Hofman A, Jaddoe VW, Raat H. Sedentary behaviors, physical activity behaviors, and body fat in 6-year-old children: the generation R study. Int J Behav Nutr Phys Act. 2014 Aug 15; 11:96. PMID: 25124336; PMCID: PMC4145220.
  523. Sinner MF, Tucker NR, Lunetta KL, Ozaki K, Smith JG, Trompet S, Bis JC, Lin H, Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J, Gollob MH, Tsunoda T, Müller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith JD, Psaty BM, Smith NL, Jukema JW, Chasman DI, Albert CM, Ebana Y, Furukawa T, Macfarlane PW, Harris TB, Darbar D, Dörr M, Holst AG, Svendsen JH, Hofman A, Uitterlinden AG, Gudnason V, Isobe M, Malik R, Dichgans M, Rosand J, Van Wagoner DR, Benjamin EJ, Milan DJ, Melander O, Heckbert SR, Ford I, Liu Y, Barnard J, Olesen MS, Stricker BH, Tanaka T, Kääb S, Ellinor PT. Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation. 2014 Oct 07; 130(15):1225-35. PMID: 25124494; PMCID: PMC4190011.
  524. Mackenbach JD, Ringoot AP, van der Ende J, Verhulst FC, Jaddoe VW, Hofman A, Jansen PW, Tiemeier HW. Exploring the relation of harsh parental discipline with child emotional and behavioral problems by using multiple informants. The generation R study. PLoS One. 2014; 9(8):e104793. PMID: 25120014; PMCID: PMC4132073.
  525. Jansen MA, Tromp II, Kiefte-de Jong JC, Jaddoe VW, Hofman A, Escher JC, Hooijkaas H, Moll HA. Infant feeding and anti-tissue transglutaminase antibody concentrations in the Generation R Study. Am J Clin Nutr. 2014 Oct; 100(4):1095-101. PMID: 25240074.
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  526. Qi Q, Kilpeläinen TO, Downer MK, Tanaka T, Smith CE, Sluijs I, Sonestedt E, Chu AY, Renström F, Lin X, Ängquist LH, Huang J, Liu Z, Li Y, Asif Ali M, Xu M, Ahluwalia TS, Boer JM, Chen P, Daimon M, Eriksson J, Perola M, Friedlander Y, Gao YT, Heppe DH, Holloway JW, Houston DK, Kanoni S, Kim YM, Laaksonen MA, Jääskeläinen T, Lee NR, Lehtimäki T, Lemaitre RN, Lu W, Luben RN, Manichaikul A, Männistö S, Marques-Vidal P, Monda KL, Ngwa JS, Perusse L, van Rooij FJ, Xiang YB, Wen W, Wojczynski MK, Zhu J, Borecki IB, Bouchard C, Cai Q, Cooper C, Dedoussis GV, Deloukas P, Ferrucci L, Forouhi NG, Hansen T, Christiansen L, Hofman A, Johansson I, Jørgensen T, Karasawa S, Khaw KT, Kim MK, Kristiansson K, Li H, Lin X, Liu Y, Lohman KK, Long J, Mikkilä V, Mozaffarian D, North K, Pedersen O, Raitakari O, Rissanen H, Tuomilehto J, van der Schouw YT, Uitterlinden AG, Zillikens MC, Franco OH, Shyong Tai E, Ou Shu X, Siscovick DS, Toft U, Verschuren WM, Vollenweider P, Wareham NJ, Witteman JC, Zheng W, Ridker PM, Kang JH, Liang L, Jensen MK, Curhan GC, Pasquale LR, Hunter DJ, Mohlke KL, Uusitupa M, Cupples LA, Rankinen T, Orho-Melander M, Wang T, Chasman DI, Franks PW, Sørensen TI, Hu FB, Loos RJ, Nettleton JA, Qi L. FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Hum Mol Genet. 2014 Dec 20; 23(25):6961-72. PMID: 25104851; PMCID: PMC4271061.
  527. Keller MF, Reiner AP, Okada Y, van Rooij FJ, Johnson AD, Chen MH, Smith AV, Morris AP, Tanaka T, Ferrucci L, Zonderman AB, Lettre G, Harris T, Garcia M, Bandinelli S, Qayyum R, Yanek LR, Becker DM, Becker LC, Kooperberg C, Keating B, Reis J, Tang H, Boerwinkle E, Kamatani Y, Matsuda K, Kamatani N, Nakamura Y, Kubo M, Liu S, Dehghan A, Felix JF, Hofman A, Uitterlinden AG, van Duijn CM, Franco OH, Longo DL, Singleton AB, Psaty BM, Evans MK, Cupples LA, Rotter JI, O'Donnell CJ, Takahashi A, Wilson JG, Ganesh SK, Nalls MA. Trans-ethnic meta-analysis of white blood cell phenotypes. Hum Mol Genet. 2014 Dec 20; 23(25):6944-60. PMID: 25096241; PMCID: PMC4245044.
  528. Sabater-Lleal M, Mälarstig A, Folkersen L, Soler Artigas M, Baldassarre D, Kavousi M, Almgren P, Veglia F, Brusselle G, Hofman A, Engström G, Franco OH, Melander O, Paulsson-Berne G, Watkins H, Eriksson P, Humphries SE, Tremoli E, de Faire U, Tobin MD, Hamsten A. Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease. PLoS One. 2014; 9(8):e104082. PMID: 25093840; PMCID: PMC4122436.
  529. Rijnbeek PR, van Herpen G, Bots ML, Man S, Verweij N, Hofman A, Hillege H, Numans ME, Swenne CA, Witteman JC, Kors JA. Normal values of the electrocardiogram for ages 16-90 years. J Electrocardiol. 2014 Nov-Dec; 47(6):914-21. PMID: 25194872.
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  530. Gaillard R, Rurangirwa AA, Williams MA, Hofman A, Mackenbach JP, Franco OH, Steegers EA, Jaddoe VW. Maternal parity, fetal and childhood growth, and cardiometabolic risk factors. Hypertension. 2014 Aug; 64(2):266-74. PMID: 24866145.
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  531. Leusink M, de Keyser CE, Onland-Moret NC, Hofman A, Visser LE, Stricker BH, de Bakker PI, de Boer A, van Schaik RH, Maitland-van der Zee AH. No association between CYP3A4*22 and statin effectiveness in reducing the risk for myocardial infarction. Pharmacogenomics. 2014 Aug; 15(11):1471-7. PMID: 25303298.
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  532. El Marroun H, White TJ, van der Knaap NJ, Homberg JR, Fernández G, Schoemaker NK, Jaddoe VW, Hofman A, Verhulst FC, Hudziak JJ, Stricker BH, Tiemeier H. Prenatal exposure to selective serotonin reuptake inhibitors and social responsiveness symptoms of autism: population-based study of young children. Br J Psychiatry. 2014 Aug; 205(2):95-102. PMID: 25252317.
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  533. Jacobs LC, Liu F, Bleyen I, Gunn DA, Hofman A, Klaver CC, Uitterlinden AG, Neumann HA, Bataille V, Spector TD, Kayser M, Nijsten T. Intrinsic and extrinsic risk factors for sagging eyelids. JAMA Dermatol. 2014 Aug; 150(8):836-43. PMID: 24869959.
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  534. White T, Muetzel R, Schmidt M, Langeslag SJ, Jaddoe V, Hofman A, Calhoun VD, Verhulst FC, Tiemeier H. Time of acquisition and network stability in pediatric resting-state functional magnetic resonance imaging. Brain Connect. 2014 Aug; 4(6):417-27. PMID: 24874884; PMCID: PMC4120810.
  535. Choté AA, Koopmans GT, de Groot CJ, Hoefman RJ, Jaddoe VW, Hofman A, Steegers EA, Mackenbach JP, Trappenburg M, Foets M. Differences in timely antenatal care between first and second-generation migrants in the Netherlands. J Immigr Minor Health. 2014 Aug; 16(4):631-7. PMID: 23702785.
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  536. Verlinden M, Veenstra R, Ghassabian A, Jansen PW, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Executive functioning and non-verbal intelligence as predictors of bullying in early elementary school. J Abnorm Child Psychol. 2014 Aug; 42(6):953-66. PMID: 24337736.
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  537. Verwoert GC, Franco OH, Hoeks AP, Reneman RS, Hofman A, V Duijn CM, Sijbrands EJ, Witteman JC, Mattace-Raso FU. Arterial stiffness and hypertension in a large population of untreated individuals: the Rotterdam Study. J Hypertens. 2014 Aug; 32(8):1606-12; discussion 1612. PMID: 24886821.
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  538. Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, Paternoster L, Porcu E, Smith AV, Stolk L, Teumer A, Tšernikova N, Tikkanen E, Ulivi S, Wagner EK, Amin N, Bierut LJ, Byrne EM, Hottenga JJ, Koller DL, Mangino M, Pers TH, Yerges-Armstrong LM, Zhao JH, Andrulis IL, Anton-Culver H, Atsma F, Bandinelli S, Beckmann MW, Benitez J, Blomqvist C, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Brenner H, Buring JE, Chang-Claude J, Chanock S, Chen J, Chenevix-Trench G, Collée JM, Couch FJ, Couper D, Coveillo AD, Cox A, Czene K, D'adamo AP, Smith GD, De Vivo I, Demerath EW, Dennis J, Devilee P, Dieffenbach AK, Dunning AM, Eiriksdottir G, Eriksson JG, Fasching PA, Ferrucci L, Flesch-Janys D, Flyger H, Foroud T, Franke L, Garcia ME, García-Closas M, Geller F, de Geus EE, Giles GG, Gudbjartsson DF, Gudnason V, Guénel P, Guo S, Hall P, Hamann U, Haring R, Hartman CA, Heath AC, Hofman A, Hooning MJ, Hopper JL, Hu FB, Hunter DJ, Karasik D, Kiel DP, Knight JA, Kosma VM, Kutalik Z, Lai S, Lambrechts D, Lindblom A, Mägi R, Magnusson PK, Mannermaa A, Martin NG, Masson G, McArdle PF, McArdle WL, Melbye M, Michailidou K, Mihailov E, Milani L, Milne RL, Nevanlinna H, Neven P, Nohr EA, Oldehinkel AJ, Oostra BA, Palotie A, Peacock M, Pedersen NL, Peterlongo P, Peto J, Pharoah PD, Postma DS, Pouta A, Pylkäs K, Radice P, Ring S, Rivadeneira F, Robino A, Rose LM, Rudolph A, Salomaa V, Sanna S, Schlessinger D, Schmidt MK, Southey MC, Sovio U, Stampfer MJ, Stöckl D, Storniolo AM, Timpson NJ, Tyrer J, Visser JA, Vollenweider P, Völzke H, Waeber G, Waldenberger M, Wallaschofski H, Wang Q, Willemsen G, Winqvist R, Wolffenbuttel BH, Wright MJ, Boomsma DI, Econs MJ, Khaw KT, Loos RJ, McCarthy MI, Montgomery GW, Rice JP, Streeten EA, Thorsteinsdottir U, van Duijn CM, Alizadeh BZ, Bergmann S, Boerwinkle E, Boyd HA, Crisponi L, Gasparini P, Gieger C, Harris TB, Ingelsson E, Järvelin MR, Kraft P, Lawlor D, Metspalu A, Pennell CE, Ridker PM, Snieder H, Sørensen TI, Spector TD, Strachan DP, Uitterlinden AG, Wareham NJ, Widen E, Zygmunt M, Murray A, Easton DF, Stefansson K, Murabito JM, Ong KK. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 2014 Oct 02; 514(7520):92-97. PMID: 25231870; PMCID: PMC4185210.
  539. Stergiakouli E, Gaillard R, Tavaré JM, Balthasar N, Loos RJ, Taal HR, Evans DM, Rivadeneira F, St Pourcain B, Uitterlinden AG, Kemp JP, Hofman A, Ring SM, Cole TJ, Jaddoe VW, Davey Smith G, Timpson NJ. Genome-wide association study of height-adjusted BMI in childhood identifies functional variant in ADCY3. Obesity (Silver Spring). 2014 Oct; 22(10):2252-9. PMID: 25044758; PMCID: PMC4265207.
  540. De Bruijn KM, Ruiter R, de Keyser CE, Hofman A, Stricker BH, van Eijck CH. Detection bias may be the main cause of increased cancer incidence among diabetics: results from the Rotterdam Study. Eur J Cancer. 2014 Sep; 50(14):2449-55. PMID: 25047425.
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  541. Sinner MF, Stepas KA, Moser CB, Krijthe BP, Aspelund T, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Vasan RS, Wang TJ, Agarwal SK, McManus DD, Franco OH, Yin X, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kääb S, Couper D, Harris TB, Astor BC, Ballantyne CM, Hoogeveen RC, Arai AE, Soliman EZ, Ellinor PT, Stricker BH, Gudnason V, Heckbert SR, Pencina MJ, Benjamin EJ, Alonso A. B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies. Europace. 2014 Oct; 16(10):1426-33. PMID: 25037055; PMCID: PMC4197895.
  542. van der Knaap NJ, El Marroun H, Klumpers F, Mous SE, Jaddoe VW, Hofman A, Homberg JR, White T, Tiemeier H, Fernández G. Beyond classical inheritance: the influence of maternal genotype upon child's brain morphology and behavior. J Neurosci. 2014 Jul 16; 34(29):9516-21. PMID: 25031395.
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  543. van Rossem L, Hafkamp-de Groen E, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. The role of early life factors in the development of ethnic differences in growth and overweight in preschool children: a prospective birth cohort. BMC Public Health. 2014 Jul 15; 14:722. PMID: 25022314; PMCID: PMC4227130.
  544. Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A, Cavadino A, Drogan D, Padmanabhan S, Li S, Yesupriya A, Leusink M, Sundstrom J, Hubacek JA, Pikhart H, Swerdlow DI, Panayiotou AG, Borinskaya SA, Finan C, Shah S, Kuchenbaecker KB, Shah T, Engmann J, Folkersen L, Eriksson P, Ricceri F, Melander O, Sacerdote C, Gamble DM, Rayaprolu S, Ross OA, McLachlan S, Vikhireva O, Sluijs I, Scott RA, Adamkova V, Flicker L, Bockxmeer FM, Power C, Marques-Vidal P, Meade T, Marmot MG, Ferro JM, Paulos-Pinheiro S, Humphries SE, Talmud PJ, Mateo Leach I, Verweij N, Linneberg A, Skaaby T, Doevendans PA, Cramer MJ, van der Harst P, Klungel OH, Dowling NF, Dominiczak AF, Kumari M, Nicolaides AN, Weikert C, Boeing H, Ebrahim S, Gaunt TR, Price JF, Lannfelt L, Peasey A, Kubinova R, Pajak A, Malyutina S, Voevoda MI, Tamosiunas A, Maitland-van der Zee AH, Norman PE, Hankey GJ, Bergmann MM, Hofman A, Franco OH, Cooper J, Palmen J, Spiering W, de Jong PA, Kuh D, Hardy R, Uitterlinden AG, Ikram MA, Ford I, Hyppönen E, Almeida OP, Wareham NJ, Khaw KT, Hamsten A, Husemoen LL, Tjønneland A, Tolstrup JS, Rimm E, Beulens JW, Verschuren WM, Onland-Moret NC, Hofker MH, Wannamethee SG, Whincup PH, Morris R, Vicente AM, Watkins H, Farrall M, Jukema JW, Meschia J, Cupples LA, Sharp SJ, Fornage M, Kooperberg C, LaCroix AZ, Dai JY, Lanktree MB, Siscovick DS, Jorgenson E, Spring B, Coresh J, Li YR, Buxbaum SG, Schreiner PJ, Ellison RC, Tsai MY, Patel SR, Redline S, Johnson AD, Hoogeveen RC, Hakonarson H, Rotter JI, Boerwinkle E, de Bakker PI, Kivimaki M, Asselbergs FW, Sattar N, Lawlor DA, Whittaker J, Davey Smith G, Mukamal K, Psaty BM, Wilson JG, Lange LA, Hamidovic A, Hingorani AD, Nordestgaard BG, Bobak M, Leon DA, Langenberg C, Palmer TM, Reiner AP, Keating BJ, Dudbridge F, Casas JP. Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ. 2014 Jul 10; 349:g4164. PMID: 25011450; PMCID: PMC4091648.
  545. Bouthoorn SH, Wijtzes AI, Jaddoe VW, Hofman A, Raat H, van Lenthe FJ. Development of socioeconomic inequalities in obesity among Dutch pre-school and school-aged children. Obesity (Silver Spring). 2014 Oct; 22(10):2230-7. PMID: 25044908.
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  546. Bolton JL, Hayward C, Direk N, Lewis JG, Hammond GL, Hill LA, Anderson A, Huffman J, Wilson JF, Campbell H, Rudan I, Wright A, Hastie N, Wild SH, Velders FP, Hofman A, Uitterlinden AG, Lahti J, Räikkönen K, Kajantie E, Widen E, Palotie A, Eriksson JG, Kaakinen M, Järvelin MR, Timpson NJ, Davey Smith G, Ring SM, Evans DM, St Pourcain B, Tanaka T, Milaneschi Y, Bandinelli S, Ferrucci L, van der Harst P, Rosmalen JG, Bakker SJ, Verweij N, Dullaart RP, Mahajan A, Lindgren CM, Morris A, Lind L, Ingelsson E, Anderson LN, Pennell CE, Lye SJ, Matthews SG, Eriksson J, Mellstrom D, Ohlsson C, Price JF, Strachan MW, Reynolds RM, Tiemeier H, Walker BR. Genome wide association identifies common variants at the SERPINA6/SERPINA1 locus influencing plasma cortisol and corticosteroid binding globulin. PLoS Genet. 2014 Jul; 10(7):e1004474. PMID: 25010111; PMCID: PMC4091794.
  547. Verlinden VJ, van der Geest JN, de Groot M, Hofman A, Niessen WJ, van der Lugt A, Vernooij MW, Ikram MA. Structural and microstructural brain changes predict impairment in daily functioning. Am J Med. 2014 Nov; 127(11):1089-96.e2. PMID: 25016128.
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  549. Elfrink ME, Moll HA, Kiefte-de Jong JC, Jaddoe VW, Hofman A, ten Cate JM, Veerkamp JS. Pre- and postnatal determinants of deciduous molar hypomineralisation in 6-year-old children. The generation R study. PLoS One. 2014; 9(7):e91057. PMID: 24988443; PMCID: PMC4079596.
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  551. Diekstra FP, Van Deerlin VM, van Swieten JC, Al-Chalabi A, Ludolph AC, Weishaupt JH, Hardiman O, Landers JE, Brown RH, van Es MA, Pasterkamp RJ, Koppers M, Andersen PM, Estrada K, Rivadeneira F, Hofman A, Uitterlinden AG, van Damme P, Melki J, Meininger V, Shatunov A, Shaw CE, Leigh PN, Shaw PJ, Morrison KE, Fogh I, Chiò A, Traynor BJ, Czell D, Weber M, Heutink P, de Bakker PI, Silani V, Robberecht W, van den Berg LH, Veldink JH. C9orf72 and UNC13A are shared risk loci for amyotrophic lateral sclerosis and frontotemporal dementia: a genome-wide meta-analysis. Ann Neurol. 2014 Jul; 76(1):120-33. PMID: 24931836; PMCID: PMC4137231.
  552. Román GC, Ghassabian A, Bongers-Schokking JJ, Jaddoe VW, Hofman A, de Rijke YB, Verhulst FC, Tiemeier H. Reply: To PMID 23943579. Ann Neurol. 2014 Jun; 75(6):971-2. PMID: 24644016.
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  553. Ganesh SK, Chasman DI, Larson MG, Guo X, Verwoert G, Bis JC, Gu X, Smith AV, Yang ML, Zhang Y, Ehret G, Rose LM, Hwang SJ, Papanicolau GJ, Sijbrands EJ, Rice K, Eiriksdottir G, Pihur V, Ridker PM, Vasan RS, Newton-Cheh C, Raffel LJ, Amin N, Rotter JI, Liu K, Launer LJ, Xu M, Caulfield M, Morrison AC, Johnson AD, Vaidya D, Dehghan A, Li G, Bouchard C, Harris TB, Zhang H, Boerwinkle E, Siscovick DS, Gao W, Uitterlinden AG, Rivadeneira F, Hofman A, Willer CJ, Franco OH, Huo Y, Witteman JC, Munroe PB, Gudnason V, Palmas W, van Duijn C, Fornage M, Levy D, Psaty BM, Chakravarti A. Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. Am J Hum Genet. 2014 Jul 03; 95(1):49-65. PMID: 24975945; PMCID: PMC4085637.
  554. Akoudad S, Ikram MA, Koudstaal PJ, Hofman A, Niessen WJ, Greenberg SM, van der Lugt A, Vernooij MW. Cerebral microbleeds are associated with the progression of ischemic vascular lesions. Cerebrovasc Dis. 2014; 37(5):382-8. PMID: 24970709.
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  556. Lundby A, Rossin EJ, Steffensen AB, Acha MR, Newton-Cheh C, Pfeufer A, Lynch SN, Olesen SP, Brunak S, Ellinor PT, Jukema JW, Trompet S, Ford I, Macfarlane PW, Krijthe BP, Hofman A, Uitterlinden AG, Stricker BH, Nathoe HM, Spiering W, Daly MJ, Asselbergs FW, van der Harst P, Milan DJ, de Bakker PI, Lage K, Olsen JV. Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics. Nat Methods. 2014 Aug; 11(8):868-74. PMID: 24952909; PMCID: PMC4117722.
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  558. Verwoert GC, Hofland J, Amin N, Mattace-Raso FU, Sijbrands EJ, Hofman A, van den Meiracker AH, Uitterlinden AG, van Duijn CM, de Jong FH, Danser AH. Expression and gene variation studies deny association of human HSD3B1 gene with aldosterone production or blood pressure. Am J Hypertens. 2015 Jan; 28(1):113-20. PMID: 24951726.
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  559. Simino J, Shi G, Bis JC, Chasman DI, Ehret GB, Gu X, Guo X, Hwang SJ, Sijbrands E, Smith AV, Verwoert GC, Bragg-Gresham JL, Cadby G, Chen P, Cheng CY, Corre T, de Boer RA, Goel A, Johnson T, Khor CC, Lluís-Ganella C, Luan J, Lyytikäinen LP, Nolte IM, Sim X, Sõber S, van der Most PJ, Verweij N, Zhao JH, Amin N, Boerwinkle E, Bouchard C, Dehghan A, Eiriksdottir G, Elosua R, Franco OH, Gieger C, Harris TB, Hercberg S, Hofman A, James AL, Johnson AD, Kähönen M, Khaw KT, Kutalik Z, Larson MG, Launer LJ, Li G, Liu J, Liu K, Morrison AC, Navis G, Ong RT, Papanicolau GJ, Penninx BW, Psaty BM, Raffel LJ, Raitakari OT, Rice K, Rivadeneira F, Rose LM, Sanna S, Scott RA, Siscovick DS, Stolk RP, Uitterlinden AG, Vaidya D, van der Klauw MM, Vasan RS, Vithana EN, Völker U, Völzke H, Watkins H, Young TL, Aung T, Bochud M, Farrall M, Hartman CA, Laan M, Lakatta EG, Lehtimäki T, Loos RJ, Lucas G, Meneton P, Palmer LJ, Rettig R, Snieder H, Tai ES, Teo YY, van der Harst P, Wareham NJ, Wijmenga C, Wong TY, Fornage M, Gudnason V, Levy D, Palmas W, Ridker PM, Rotter JI, van Duijn CM, Witteman JC, Chakravarti A, Rao DC. Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. Am J Hum Genet. 2014 Jul 03; 95(1):24-38. PMID: 24954895; PMCID: PMC4085636.
  560. Kemp JP, Medina-Gomez C, Estrada K, St Pourcain B, Heppe DH, Warrington NM, Oei L, Ring SM, Kruithof CJ, Timpson NJ, Wolber LE, Reppe S, Gautvik K, Grundberg E, Ge B, van der Eerden B, van de Peppel J, Hibbs MA, Ackert-Bicknell CL, Choi K, Koller DL, Econs MJ, Williams FM, Foroud T, Zillikens MC, Ohlsson C, Hofman A, Uitterlinden AG, Davey Smith G, Jaddoe VW, Tobias JH, Rivadeneira F, Evans DM. Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment. PLoS Genet. 2014 Jun; 10(6):e1004423. PMID: 24945404; PMCID: PMC4063697.
  561. Lahousse L, Maes B, Ziere G, Loth DW, Verlinden VJ, Zillikens MC, Uitterlinden AG, Rivadeneira F, Tiemeier H, Franco OH, Ikram MA, Hofman A, Brusselle GG, Stricker BH. Adverse outcomes of frailty in the elderly: the Rotterdam Study. Eur J Epidemiol. 2014 Jun; 29(6):419-27. PMID: 24935872.
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  562. Loth DW, Soler Artigas M, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, Ramasamy A, Wareham NJ, Kaprio J, Wang XQ, Trochet H, Kähönen M, Flexeder C, Albrecht E, Lopez LM, de Jong K, Thyagarajan B, Alves AC, Enroth S, Omenaas E, Joshi PK, Fall T, Viñuela A, Launer LJ, Loehr LR, Fornage M, Li G, Wilk JB, Tang W, Manichaikul A, Lahousse L, Harris TB, North KE, Rudnicka AR, Hui J, Gu X, Lumley T, Wright AF, Hastie ND, Campbell S, Kumar R, Pin I, Scott RA, Pietiläinen KH, Surakka I, Liu Y, Holliday EG, Schulz H, Heinrich J, Davies G, Vonk JM, Wojczynski M, Pouta A, Johansson A, Wild SH, Ingelsson E, Rivadeneira F, Völzke H, Hysi PG, Eiriksdottir G, Morrison AC, Rotter JI, Gao W, Postma DS, White WB, Rich SS, Hofman A, Aspelund T, Couper D, Smith LJ, Psaty BM, Lohman K, Burchard EG, Uitterlinden AG, Garcia M, Joubert BR, McArdle WL, Musk AB, Hansel N, Heckbert SR, Zgaga L, van Meurs JB, Navarro P, Rudan I, Oh YM, Redline S, Jarvis DL, Zhao JH, Rantanen T, O'Connor GT, Ripatti S, Scott RJ, Karrasch S, Grallert H, Gaddis NC, Starr JM, Wijmenga C, Minster RL, Lederer DJ, Pekkanen J, Gyllensten U, Campbell H, Morris AP, Gläser S, Hammond CJ, Burkart KM, Beilby J, Kritchevsky SB, Gudnason V, Hancock DB, Williams OD, Polasek O, Zemunik T, Kolcic I, Petrini MF, Wjst M, Kim WJ, Porteous DJ, Scotland G, Smith BH, Viljanen A, Heliövaara M, Attia JR, Sayers I, Hampel R, Gieger C, Deary IJ, Boezen HM, Newman A, Jarvelin MR, Wilson JF, Lind L, Stricker BH, Teumer A, Spector TD, Melén E, Peters MJ, Lange LA, Barr RG, Bracke KR, Verhamme FM, Sung J, Hiemstra PS, Cassano PA, Sood A, Hayward C, Dupuis J, Hall IP, Brusselle GG, Tobin MD, London SJ. Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nat Genet. 2014 Jul; 46(7):669-77. PMID: 24929828; PMCID: PMC4140093.
  563. Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hernández I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-García A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. PLoS One. 2014; 9(6):e94661. PMID: 24922517; PMCID: PMC4055488.
  564. Ghassabian A, Steenweg-de Graaff J, Peeters RP, Ross HA, Jaddoe VW, Hofman A, Verhulst FC, White T, Tiemeier H. Maternal urinary iodine concentration in pregnancy and children's cognition: results from a population-based birth cohort in an iodine-sufficient area. BMJ Open. 2014 Jun 12; 4(6):e005520. PMID: 24928597; PMCID: PMC4067856.
  565. Versmissen J, Oosterveer DM, Yazdanpanah M, Dehghan A, Hólm H, Erdman J, Aulchenko YS, Thorleifsson G, Schunkert H, Huijgen R, Vongpromek R, Uitterlinden AG, Defesche JC, van Duijn CM, Mulder M, Dadd T, Karlsson HD, Ordovas J, Kindt I, Jarman A, Hofman A, van Vark-van der Zee L, Blommesteijn-Touw AC, Kwekkeboom J, Liem AH, van der Ouderaa FJ, Calandra S, Bertolini S, Averna M, Langslet G, Ose L, Ros E, Almagro F, de Leeuw PW, Civeira F, Masana L, Pintó X, Simoons ML, Schinkel AF, Green MR, Zwinderman AH, Johnson KJ, Schaefer A, Neil A, Witteman JC, Humphries SE, Kastelein JJ, Sijbrands EJ. Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach. Eur J Hum Genet. 2015 Mar; 23(3):381-7. PMID: 24916650; PMCID: PMC4326701.
  566. Vucic S, de Vries E, Eilers PH, Willemsen SP, Kuijpers MA, Prahl-Andersen B, Jaddoe VW, Hofman A, Wolvius EB, Ongkosuwito EM. Secular trend of dental development in Dutch children. Am J Phys Anthropol. 2014 Sep; 155(1):91-8. PMID: 24912457.
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  567. Korevaar TI, Steegers EA, Schalekamp-Timmermans S, Ligthart S, de Rijke YB, Visser WE, Visser W, de Muinck Keizer-Schrama SM, Hofman A, Hooijkaas H, Bongers-Schokking JJ, Russcher H, Tiemeier H, Jaddoe VW, Visser TJ, Medici M, Peeters RP. Soluble Flt1 and placental growth factor are novel determinants of newborn thyroid (dys)function: the generation R study. J Clin Endocrinol Metab. 2014 Sep; 99(9):E1627-34. PMID: 24885632.
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  568. Kooijman MN, de Jonge LL, Steegers EA, van Osch-Gevers L, Verburg BO, Hofman A, Helbing WA, Jaddoe VW. Third trimester fetal hemodynamics and cardiovascular outcomes in childhood: the Generation R study. J Hypertens. 2014 Jun; 32(6):1275-82. PMID: 24682032.
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  569. Aarts N, Akoudad S, Noordam R, Hofman A, Ikram MA, Stricker BH, Visser LE, Vernooij MW. Inhibition of serotonin reuptake by antidepressants and cerebral microbleeds in the general population. Stroke. 2014 Jul; 45(7):1951-7. PMID: 24876079.
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  570. Klein R, Myers CE, Buitendijk GH, Rochtchina E, Gao X, de Jong PT, Sivakumaran TA, Burlutsky G, McKean-Cowdin R, Hofman A, Iyengar SK, Lee KE, Stricker BH, Vingerling JR, Mitchell P, Klein BE, Klaver CC, Wang JJ. Lipids, lipid genes, and incident age-related macular degeneration: the three continent age-related macular degeneration consortium. Am J Ophthalmol. 2014 Sep; 158(3):513-24.e3. PMID: 24879949; PMCID: PMC4138281.
  571. Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpeläinen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD, Feitosa MF, Tekola-Ayele F, Chu AY, Nolte IM, Dastani Z, Morris A, Pendergrass SA, Sun YV, Ritchie MD, Vaez A, Lin H, Ligthart S, Marullo L, Rohde R, Shao Y, Ziegler MA, Im HK, Schnabel RB, Jørgensen T, Jørgensen ME, Hansen T, Pedersen O, Stolk RP, Snieder H, Hofman A, Uitterlinden AG, Franco OH, Ikram MA, Richards JB, Rotimi C, Wilson JG, Lange L, Ganesh SK, Nalls M, Rasmussen-Torvik LJ, Pankow JS, Coresh J, Tang W, Linda Kao WH, Boerwinkle E, Morrison AC, Ridker PM, Becker DM, Rotter JI, Kardia SL, Loos RJ, Larson MG, Hsu YH, Province MA, Tracy R, Voight BF, Vaidya D, O'Donnell CJ, Benjamin EJ, Alizadeh BZ, Prokopenko I, Meigs JB, Borecki IB. Pleiotropic genes for metabolic syndrome and inflammation. Mol Genet Metab. 2014 Aug; 112(4):317-38. PMID: 24981077; PMCID: PMC4122618.
  572. Kooijman MN, Bakker H, van der Heijden AJ, Hofman A, Franco OH, Steegers EA, Taal HR, Jaddoe VW. Childhood kidney outcomes in relation to fetal blood flow and kidney size. J Am Soc Nephrol. 2014 Nov; 25(11):2616-24. PMID: 24812167; PMCID: PMC4214517.
  573. Bakker H, Gaillard R, Franco OH, Hofman A, van der Heijden AJ, Steegers EA, Taal HR, Jaddoe VW. Fetal and infant growth patterns and kidney function at school age. J Am Soc Nephrol. 2014 Nov; 25(11):2607-15. PMID: 24812164; PMCID: PMC4214527.
  574. Basten M, van der Ende J, Tiemeier H, Althoff RR, Rijlaarsdam J, Jaddoe VW, Hofman A, Hudziak JJ, Verhulst FC, White T. Nonverbal intelligence in young children with dysregulation: the Generation R Study. Eur Child Adolesc Psychiatry. 2014 Nov; 23(11):1061-70. PMID: 24802760.
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  575. de Keyser CE, Koehler EM, Schouten JN, Visser LE, Hofman A, Janssen HL, Stricker BH. Statin therapy is associated with a reduced risk of non-alcoholic fatty liver in overweight individuals. Dig Liver Dis. 2014 Aug; 46(8):720-5. PMID: 24815080.
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  576. Turin TC, Matsushita K, Coresh J, Arima H, Chadban SJ, Cirillo M, Djurdjev O, Green JA, Irie F, Ix JH, Kovesdy CP, Ohkubo T, Shankar A, Wen CP, De Jong PE, Iseki K, Stengel B, Gansevoort RT, De Nicola L, Donfrancesco C, Minutolo R, Iacoviello L, Zoccali C, Gesualdo L, Conte G, Vanuzzo D, Giampaoli S, Gorriz JL, Molina-Vila P, Nieto J, Bover J, Martinez-Castelao A, Martinde Francisco AL, Barril G, Del Pino MD, Escudero V, Coresh J, Matsushita K, Sang Y, Ballew SH, Appel LJ, Green JA, Heine GH, Inker LA, Ishani A, Marks A, Shalev V, Turin TC, Iseki K, Levey AS, Sedaghat S, Mattace-Raso FU, Uitterlinden AG, Hoorn EJ, Hofman A, Ikram MA, Franco OH, Dehghan A. Ckd epidemiology. Nephrol Dial Transplant. 2014 May; 29 Suppl 3:iii54-iii55. PMID: 24850007.
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  577. Leening MJ, Heeringa J, Deckers JW, Franco OH, Hofman A, Witteman JC, Stricker BH. Healthy volunteer effect and cardiovascular risk. Epidemiology. 2014 May; 25(3):470-1. PMID: 24713887.
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  578. Bos MJ, Koudstaal PJ, Hofman A, Ikram MA. Modifiable etiological factors and the burden of stroke from the Rotterdam study: a population-based cohort study. PLoS Med. 2014 Apr; 11(4):e1001634. PMID: 24781247; PMCID: PMC4004543.
  579. Ferket BS, van Kempen BJ, Wieberdink RG, Steyerberg EW, Koudstaal PJ, Hofman A, Shahar E, Gottesman RF, Rosamond W, Kizer JR, Kronmal RA, Psaty BM, Longstreth WT, Mosley T, Folsom AR, Hunink MG, Ikram MA. Separate prediction of intracerebral hemorrhage and ischemic stroke. Neurology. 2014 May 20; 82(20):1804-12. PMID: 24759844; PMCID: PMC4035707.
  580. Jusko TA, Shaw PA, Snijder CA, Pierik FH, Koch HM, Hauser R, Jaddoe VW, Burdorf A, Hofman A, Tiemeier H, Longnecker MP. Reproducibility of urinary bisphenol A concentrations measured during pregnancy in the Generation R Study. J Expo Sci Environ Epidemiol. 2014 Sep-Oct; 24(5):532-6. PMID: 24736100; PMCID: PMC4140995.
  581. Duvvari MR, Paun CC, Buitendijk GH, Saksens NT, Volokhina EB, Ristau T, Schoenmaker-Koller FE, van de Ven JP, Groenewoud JM, van den Heuvel LP, Hofman A, Fauser S, Uitterlinden AG, Klaver CC, Hoyng CB, de Jong EK, den Hollander AI. Analysis of rare variants in the C3 gene in patients with age-related macular degeneration. PLoS One. 2014; 9(4):e94165. PMID: 24736606; PMCID: PMC3988049.
  582. Styrkarsdottir U, Thorleifsson G, Helgadottir HT, Bomer N, Metrustry S, Bierma-Zeinstra S, Strijbosch AM, Evangelou E, Hart D, Beekman M, Jonasdottir A, Sigurdsson A, Eiriksson FF, Thorsteinsdottir M, Frigge ML, Kong A, Gudjonsson SA, Magnusson OT, Masson G, Hofman A, Arden NK, Ingvarsson T, Lohmander S, Kloppenburg M, Rivadeneira F, Nelissen RG, Spector T, Uitterlinden A, Slagboom PE, Thorsteinsdottir U, Jonsdottir I, Valdes AM, Meulenbelt I, van Meurs J, Jonsson H, Stefansson K. Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31. Nat Genet. 2014 May; 46(5):498-502. PMID: 24728293.
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  583. Ghassabian A, Székely E, Herba CM, Jaddoe VW, Hofman A, Oldehinkel AJ, Verhulst FC, Tiemeier H. From positive emotionality to internalizing problems: the role of executive functioning in preschoolers. Eur Child Adolesc Psychiatry. 2014 Sep; 23(9):729-41. PMID: 24728546.
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  584. Kavousi M, Leening MJ, Nanchen D, Greenland P, Graham IM, Steyerberg EW, Ikram MA, Stricker BH, Hofman A, Franco OH. Comparison of application of the ACC/AHA guidelines, Adult Treatment Panel III guidelines, and European Society of Cardiology guidelines for cardiovascular disease prevention in a European cohort. JAMA. 2014 Apr 09; 311(14):1416-23. PMID: 24681960.
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  585. Krijthe BP, Heeringa J, Hofman A, Franco OH, Stricker BH. Non-steroidal anti-inflammatory drugs and the risk of atrial fibrillation: a population-based follow-up study. BMJ Open. 2014 Apr 08; 4(4):e004059. PMID: 24713211; PMCID: PMC3987714.
  586. Gishti O, Gaillard R, Manniesing R, Abrahamse-Berkeveld M, van der Beek EM, Heppe DH, Steegers EA, Hofman A, Duijts L, Durmus B, Jaddoe VW. Fetal and infant growth patterns associated with total and abdominal fat distribution in school-age children. J Clin Endocrinol Metab. 2014 Jul; 99(7):2557-66. PMID: 24712569.
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  587. Rodriguez-Fontenla C, Calaza M, Evangelou E, Valdes AM, Arden N, Blanco FJ, Carr A, Chapman K, Deloukas P, Doherty M, Esko T, Garcés Aletá CM, Gomez-Reino Carnota JJ, Helgadottir H, Hofman A, Jonsdottir I, Kerkhof HJ, Kloppenburg M, McCaskie A, Ntzani EE, Ollier WE, Oreiro N, Panoutsopoulou K, Ralston SH, Ramos YF, Riancho JA, Rivadeneira F, Slagboom PE, Styrkarsdottir U, Thorsteinsdottir U, Thorleifsson G, Tsezou A, Uitterlinden AG, Wallis GA, Wilkinson JM, Zhai G, Zhu Y, Felson DT, Ioannidis JP, Loughlin J, Metspalu A, Meulenbelt I, Stefansson K, van Meurs JB, Zeggini E, Spector TD, Gonzalez A. Assessment of osteoarthritis candidate genes in a meta-analysis of nine genome-wide association studies. Arthritis Rheumatol. 2014 Apr; 66(4):940-9. PMID: 24757145; PMCID: PMC4660891.
  588. Bos D, Portegies ML, van der Lugt A, Bos MJ, Koudstaal PJ, Hofman A, Krestin GP, Franco OH, Vernooij MW, Ikram MA. Intracranial carotid artery atherosclerosis and the risk of stroke in whites: the Rotterdam Study. JAMA Neurol. 2014 Apr; 71(4):405-11. PMID: 24535643.
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  589. Dierckx B, Kok R, Tulen JH, Jaddoe VW, Hofman A, Verhulst FC, Bakermans-Kranenburg MJ, van Ijzendoorn MH, Tiemeier H. A prospective study of heart rate and externalising behaviours in young children. J Child Psychol Psychiatry. 2014 Apr; 55(4):402-10. PMID: 24795956.
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  590. Ghassabian A, El Marroun H, Peeters RP, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, White T. Downstream effects of maternal hypothyroxinemia in early pregnancy: nonverbal IQ and brain morphology in school-age children. J Clin Endocrinol Metab. 2014 Jul; 99(7):2383-90. PMID: 24684462.
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  591. Deelen J, Beekman M, Uh HW, Broer L, Ayers KL, Tan Q, Kamatani Y, Bennet AM, Tamm R, Trompet S, Guðbjartsson DF, Flachsbart F, Rose G, Viktorin A, Fischer K, Nygaard M, Cordell HJ, Crocco P, van den Akker EB, Böhringer S, Helmer Q, Nelson CP, Saunders GI, Alver M, Andersen-Ranberg K, Breen ME, van der Breggen R, Caliebe A, Capri M, Cevenini E, Collerton JC, Dato S, Davies K, Ford I, Gampe J, Garagnani P, de Geus EJ, Harrow J, van Heemst D, Heijmans BT, Heinsen FA, Hottenga JJ, Hofman A, Jeune B, Jonsson PV, Lathrop M, Lechner D, Martin-Ruiz C, Mcnerlan SE, Mihailov E, Montesanto A, Mooijaart SP, Murphy A, Nohr EA, Paternoster L, Postmus I, Rivadeneira F, Ross OA, Salvioli S, Sattar N, Schreiber S, Stefánsson H, Stott DJ, Tiemeier H, Uitterlinden AG, Westendorp RG, Willemsen G, Samani NJ, Galan P, Sørensen TI, Boomsma DI, Jukema JW, Rea IM, Passarino G, de Craen AJ, Christensen K, Nebel A, Stefánsson K, Metspalu A, Magnusson P, Blanché H, Christiansen L, Kirkwood TB, van Duijn CM, Franceschi C, Houwing-Duistermaat JJ, Slagboom PE. Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Hum Mol Genet. 2014 Aug 15; 23(16):4420-32. PMID: 24688116; PMCID: PMC4103672.
  592. Strawbridge RJ, Deleskog A, McLeod O, Folkersen L, Kavousi M, Gertow K, Baldassarre D, Veglia F, Leander K, Gigante B, Kauhanen J, Rauramaa R, Smit AJ, Mannarino E, Giral P, Dehghan A, Hofman A, Franco OH, Humphries SE, Tremoli E, de Faire U, Gustafsson S, Östensson CG, Eriksson P, Öhrvik J, Hamsten A. A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness). Diabetologia. 2014 Jun; 57(6):1159-72. PMID: 24663808.
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  593. Rijlaarsdam J, Stevens GW, Jansen PW, Ringoot AP, Jaddoe VW, Hofman A, Ayer L, Verhulst FC, Hudziak JJ, Tiemeier H. Maternal Childhood Maltreatment and Offspring Emotional and Behavioral Problems: Maternal and Paternal Mechanisms of Risk Transmission. Child Maltreat. 2014 May; 19(2):67-78. PMID: 24642695.
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  594. de Bruijn RF, Direk N, Mirza SS, Hofman A, Koudstaal PJ, Tiemeier H, Ikram MA. Anxiety is not associated with the risk of dementia or cognitive decline: the Rotterdam Study. Am J Geriatr Psychiatry. 2014 Dec; 22(12):1382-90. PMID: 24745561.
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  595. Adams HH, Verhaaren BF, Vrooman HA, Uitterlinden AG, Hofman A, van Duijn CM, van der Lugt A, Niessen WJ, Vernooij MW, Ikram MA. TMEM106B influences volume of left-sided temporal lobe and interhemispheric structures in the general population. Biol Psychiatry. 2014 Sep 15; 76(6):503-8. PMID: 24731779.
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  596. Bouthoorn SH, van Lenthe FJ, Gaillard R, Hofman A, Steegers EA, Jaddoe VW, Raat H. Socioeconomic inequalities in placental vascular resistance: a prospective cohort study. Fertil Steril. 2014 May; 101(5):1367-74. PMID: 24636396.
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  597. Hafkamp-de Groen E, van der Valk RJ, Mohangoo AD, van der Wouden JC, Duijts L, Jaddoe VW, Hofman A, de Koning HJ, de Jongste JC, Raat H. Evaluation of systematic assessment of asthma-like symptoms and tobacco smoke exposure in early childhood by well-child professionals: a randomised trial. PLoS One. 2014; 9(3):e90982. PMID: 24626147; PMCID: PMC3953324.
  598. Durmus B, Heppe DH, Gishti O, Manniesing R, Abrahamse-Berkeveld M, van der Beek EM, Hofman A, Duijts L, Gaillard R, Jaddoe VW. General and abdominal fat outcomes in school-age children associated with infant breastfeeding patterns. Am J Clin Nutr. 2014 Jun; 99(6):1351-8. PMID: 24622802.
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  599. Bots ML, Groenewegen KA, Anderson TJ, Britton AR, Dekker JM, Engström G, Evans GW, de Graaf J, Grobbee DE, Hedblad B, Hofman A, Holewijn S, Ikeda A, Kavousi M, Kitagawa K, Kitamura A, Ikram MA, Lonn EM, Lorenz MW, Mathiesen EB, Nijpels G, Okazaki S, O'Leary DH, Polak JF, Price JF, Robertson C, Rembold CM, Rosvall M, Rundek T, Salonen JT, Sitzer M, Stehouwer CD, Franco OH, Peters SA, den Ruijter HM. Common carotid intima-media thickness measurements do not improve cardiovascular risk prediction in individuals with elevated blood pressure: the USE-IMT collaboration. Hypertension. 2014 Jun; 63(6):1173-81. PMID: 24614213; PMCID: PMC4523133.
  600. Bakker H, Kooijman MN, van der Heijden AJ, Hofman A, Franco OH, Taal HR, Jaddoe VW. Kidney size and function in a multi-ethnic population-based cohort of school-age children. Pediatr Nephrol. 2014 Sep; 29(9):1589-98. PMID: 24599444.
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  601. Gaillard R, Steegers EA, de Jongste JC, Hofman A, Jaddoe VW. Tracking of fetal growth characteristics during different trimesters and the risks of adverse birth outcomes. Int J Epidemiol. 2014 Aug; 43(4):1140-53. PMID: 24603318; PMCID: PMC4258770.
  602. Medici M, Porcu E, Pistis G, Teumer A, Brown SJ, Jensen RA, Rawal R, Roef GL, Plantinga TS, Vermeulen SH, Lahti J, Simmonds MJ, Husemoen LL, Freathy RM, Shields BM, Pietzner D, Nagy R, Broer L, Chaker L, Korevaar TI, Plia MG, Sala C, Völker U, Richards JB, Sweep FC, Gieger C, Corre T, Kajantie E, Thuesen B, Taes YE, Visser WE, Hattersley AT, Kratzsch J, Hamilton A, Li W, Homuth G, Lobina M, Mariotti S, Soranzo N, Cocca M, Nauck M, Spielhagen C, Ross A, Arnold A, van de Bunt M, Liyanarachchi S, Heier M, Grabe HJ, Masciullo C, Galesloot TE, Lim EM, Reischl E, Leedman PJ, Lai S, Delitala A, Bremner AP, Philips DI, Beilby JP, Mulas A, Vocale M, Abecasis G, Forsen T, James A, Widen E, Hui J, Prokisch H, Rietzschel EE, Palotie A, Feddema P, Fletcher SJ, Schramm K, Rotter JI, Kluttig A, Radke D, Traglia M, Surdulescu GL, He H, Franklyn JA, Tiller D, Vaidya B, de Meyer T, Jørgensen T, Eriksson JG, O'Leary PC, Wichmann E, Hermus AR, Psaty BM, Ittermann T, Hofman A, Bosi E, Schlessinger D, Wallaschofski H, Pirastu N, Aulchenko YS, de la Chapelle A, Netea-Maier RT, Gough SC, Meyer Zu Schwabedissen H, Frayling TM, Kaufman JM, Linneberg A, Räikkönen K, Smit JW, Kiemeney LA, Rivadeneira F, Uitterlinden AG, Walsh JP, Meisinger C, den Heijer M, Visser TJ, Spector TD, Wilson SG, Völzke H, Cappola A, Toniolo D, Sanna S, Naitza S, Peeters RP. Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease. PLoS Genet. 2014 Feb; 10(2):e1004123. PMID: 24586183; PMCID: PMC3937134.
  603. Huang J, Huffman JE, Yamakuchi M, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët DA, Chen WM, Smith NL, Kleber ME, Shin SY, Becker DM, Tang W, Dehghan A, Johnson AD, Truong V, Folkersen L, Yang Q, Oudot-Mellkah T, Buckley BM, Moore JH, Williams FM, Campbell H, Silbernagel G, Vitart V, Rudan I, Tofler GH, Navis GJ, Destefano A, Wright AF, Chen MH, de Craen AJ, Worrall BB, Rudnicka AR, Rumley A, Bookman EB, Psaty BM, Chen F, Keene KL, Franco OH, Böhm BO, Uitterlinden AG, Carter AM, Jukema JW, Sattar N, Bis JC, Ikram MA, Sale MM, McKnight B, Fornage M, Ford I, Taylor K, Slagboom PE, McArdle WL, Hsu FC, Franco-Cereceda A, Goodall AH, Yanek LR, Furie KL, Cushman M, Hofman A, Witteman JC, Folsom AR, Basu S, Matijevic N, van Gilst WH, Wilson JF, Westendorp RG, Kathiresan S, Reilly MP, Tracy RP, Polasek O, Winkelmann BR, Grant PJ, Hillege HL, Cambien F, Stott DJ, Lowe GD, Spector TD, Meigs JB, Marz W, Eriksson P, Becker LC, Morange PE, Soranzo N, Williams SM, Hayward C, van der Harst P, Hamsten A, Lowenstein CJ, Strachan DP, O'Donnell CJ. Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol. 2014 May; 34(5):1093-101. PMID: 24578379; PMCID: PMC4009733.
  604. Campos-Obando N, Castano-Betancourt MC, Oei L, Franco OH, Stricker BH, Brusselle GG, Lahousse L, Hofman A, Tiemeier H, Rivadeneira F, Uitterlinden AG, Zillikens MC. Bone mineral density and chronic lung disease mortality: the rotterdam study. J Clin Endocrinol Metab. 2014 May; 99(5):1834-42. PMID: 24606086.
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  605. Medici M, Direk N, Visser WE, Korevaar TI, Hofman A, Visser TJ, Tiemeier H, Peeters RP. Thyroid function within the normal range and the risk of depression: a population-based cohort study. J Clin Endocrinol Metab. 2014 Apr; 99(4):1213-9. PMID: 24564323.
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  606. Hoogendam YY, Hofman A, van der Geest JN, van der Lugt A, Ikram MA. Patterns of cognitive function in aging: the Rotterdam Study. Eur J Epidemiol. 2014 Feb; 29(2):133-40. PMID: 24553905.
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  607. Mirza SS, de Bruijn RF, Direk N, Hofman A, Koudstaal PJ, Ikram MA, Tiemeier H. Depressive symptoms predict incident dementia during short- but not long-term follow-up period. Alzheimers Dement. 2014 Oct; 10(5 Suppl):S323-S329.e1. PMID: 24530024.
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  608. Verlinden M, Tiemeier H, Veenstra R, Mieloo CL, Jansen W, Jaddoe VW, Raat H, Hofman A, Verhulst FC, Jansen PW. Television viewing through ages 2-5 years and bullying involvement in early elementary school. BMC Public Health. 2014 Feb 12; 14:157. PMID: 24520886; PMCID: PMC3944918.
  609. Verlinden M, Veenstra R, Ringoot AP, Jansen PW, Raat H, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Detecting bullying in early elementary school with a computerized peer-nomination instrument. Psychol Assess. 2014 Jun; 26(2):628-41. PMID: 24512423.
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  610. Gaillard R, Eilers PH, Yassine S, Hofman A, Steegers EA, Jaddoe VW. Risk factors and consequences of maternal anaemia and elevated haemoglobin levels during pregnancy: a population-based prospective cohort study. Paediatr Perinat Epidemiol. 2014 May; 28(3):213-26. PMID: 24506330.
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  611. Tharner A, Jansen PW, Kiefte-de Jong JC, Moll HA, van der Ende J, Jaddoe VW, Hofman A, Tiemeier H, Franco OH. Toward an operative diagnosis of fussy/picky eating: a latent profile approach in a population-based cohort. Int J Behav Nutr Phys Act. 2014 Feb 10; 11:14. PMID: 24512388; PMCID: PMC3922255.
  612. Mahajan A, Go MJ, Zhang W, Below JE, Gaulton KJ, Ferreira T, Horikoshi M, Johnson AD, Ng MC, Prokopenko I, Saleheen D, Wang X, Zeggini E, Abecasis GR, Adair LS, Almgren P, Atalay M, Aung T, Baldassarre D, Balkau B, Bao Y, Barnett AH, Barroso I, Basit A, Been LF, Beilby J, Bell GI, Benediktsson R, Bergman RN, Boehm BO, Boerwinkle E, Bonnycastle LL, Burtt N, Cai Q, Campbell H, Carey J, Cauchi S, Caulfield M, Chan JC, Chang LC, Chang TJ, Chang YC, Charpentier G, Chen CH, Chen H, Chen YT, Chia KS, Chidambaram M, Chines PS, Cho NH, Cho YM, Chuang LM, Collins FS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Danesh J, Das D, de Faire U, Dedoussis G, Deloukas P, Dimas AS, Dina C, Doney AS, Donnelly PJ, Dorkhan M, van Duijn C, Dupuis J, Edkins S, Elliott P, Emilsson V, Erbel R, Eriksson JG, Escobedo J, Esko T, Eury E, Florez JC, Fontanillas P, Forouhi NG, Forsen T, Fox C, Fraser RM, Frayling TM, Froguel P, Frossard P, Gao Y, Gertow K, Gieger C, Gigante B, Grallert H, Grant GB, Grrop LC, Groves CJ, Grundberg E, Guiducci C, Hamsten A, Han BG, Hara K, Hassanali N, Hattersley AT, Hayward C, Hedman AK, Herder C, Hofman A, Holmen OL, Hovingh K, Hreidarsson AB, Hu C, Hu FB, Hui J, Humphries SE, Hunt SE, Hunter DJ, Hveem K, Hydrie ZI, Ikegami H, Illig T, Ingelsson E, Islam M, Isomaa B, Jackson AU, Jafar T, James A, Jia W, Jöckel KH, Jonsson A, Jowett JB, Kadowaki T, Kang HM, Kanoni S, Kao WH, Kathiresan S, Kato N, Katulanda P, Keinanen-Kiukaanniemi KM, Kelly AM, Khan H, Khaw KT, Khor CC, Kim HL, Kim S, Kim YJ, Kinnunen L, Klopp N, Kong A, Korpi-Hyövälti E, Kowlessur S, Kraft P, Kravic J, Kristensen MM, Krithika S, Kumar A, Kumate J, Kuusisto J, Kwak SH, Laakso M, Lagou V, Lakka TA, Langenberg C, Langford C, Lawrence R, Leander K, Lee JM, Lee NR, Li M, Li X, Li Y, Liang J, Liju S, Lim WY, Lind L, Lindgren CM, Lindholm E, Liu CT, Liu JJ, Lobbens S, Long J, Loos RJ, Lu W, Luan J, Lyssenko V, Ma RC, Maeda S, Mägi R, Männisto S, Matthews DR, Meigs JB, Melander O, Metspalu A, Meyer J, Mirza G, Mihailov E, Moebus S, Mohan V, Mohlke KL, Morris AD, Mühleisen TW, Müller-Nurasyid M, Musk B, Nakamura J, Nakashima E, Navarro P, Ng PK, Nica AC, Nilsson PM, Njølstad I, Nöthen MM, Ohnaka K, Ong TH, Owen KR, Palmer CN, Pankow JS, Park KS, Parkin M, Pechlivanis S, Pedersen NL, Peltonen L, Perry JR, Peters A, Pinidiyapathirage JM, Platou CG, Potter S, Price JF, Qi L, Radha V, Rallidis L, Rasheed A, Rathman W, Rauramaa R, Raychaudhuri S, Rayner NW, Rees SD, Rehnberg E, Ripatti S, Robertson N, Roden M, Rossin EJ, Rudan I, Rybin D, Saaristo TE, Salomaa V, Saltevo J, Samuel M, Sanghera DK, Saramies J, Scott J, Scott LJ, Scott RA, Segrè AV, Sehmi J, Sennblad B, Shah N, Shah S, Shera AS, Shu XO, Shuldiner AR, Sigurdsson G, Sijbrands E, Silveira A, Sim X, Sivapalaratnam S, Small KS, So WY, Stancáková A, Stefansson K, Steinbach G, Steinthorsdottir V, Stirrups K, Strawbridge RJ, Stringham HM, Sun Q, Suo C, Syvänen AC, Takayanagi R, Takeuchi F, Tay WT, Teslovich TM, Thorand B, Thorleifsson G, Thorsteinsdottir U, Tikkanen E, Trakalo J, Tremoli E, Trip MD, Tsai FJ, Tuomi T, Tuomilehto J, Uitterlinden AG, Valladares-Salgado A, Vedantam S, Veglia F, Voight BF, Wang C, Wareham NJ, Wennauer R, Wickremasinghe AR, Wilsgaard T, Wilson JF, Wiltshire S, Winckler W, Wong TY, Wood AR, Wu JY, Wu Y, Yamamoto K, Yamauchi T, Yang M, Yengo L, Yokota M, Young R, Zabaneh D, Zhang F, Zhang R, Zheng W, Zimmet PZ, Altshuler D, Bowden DW, Cho YS, Cox NJ, Cruz M, Hanis CL, Kooner J, Lee JY, Seielstad M, Teo YY, Boehnke M, Parra EJ, Chambers JC, Tai ES, McCarthy MI, Morris AP. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Mar; 46(3):234-44. PMID: 24509480; PMCID: PMC3969612.
  613. Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, Flannick J, Zhang J, Fuchsberger C, Gaulton K, Lindgren C, Locke A, Manning A, Sim X, Rivas MA, Holmen OL, Gottesman O, Lu Y, Ruderfer D, Stahl EA, Duan Q, Li Y, Durda P, Jiao S, Isaacs A, Hofman A, Bis JC, Correa A, Griswold ME, Jakobsdottir J, Smith AV, Schreiner PJ, Feitosa MF, Zhang Q, Huffman JE, Crosby J, Wassel CL, Do R, Franceschini N, Martin LW, Robinson JG, Assimes TL, Crosslin DR, Rosenthal EA, Tsai M, Rieder MJ, Farlow DN, Folsom AR, Lumley T, Fox ER, Carlson CS, Peters U, Jackson RD, van Duijn CM, Uitterlinden AG, Levy D, Rotter JI, Taylor HA, Gudnason V, Siscovick DS, Fornage M, Borecki IB, Hayward C, Rudan I, Chen YE, Bottinger EP, Loos RJ, Sætrom P, Hveem K, Boehnke M, Groop L, McCarthy M, Meitinger T, Ballantyne CM, Gabriel SB, O'Donnell CJ, Post WS, North KE, Reiner AP, Boerwinkle E, Psaty BM, Altshuler D, Kathiresan S, Lin DY, Jarvik GP, Cupples LA, Kooperberg C, Wilson JG, Nickerson DA, Abecasis GR, Rich SS, Tracy RP, Willer CJ. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. Am J Hum Genet. 2014 Feb 06; 94(2):233-45. PMID: 24507775; PMCID: PMC3928660.
  614. Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, Isaacs A, Jakobsdottir J, Feitosa MF, Davies G, Huffman JE, Manichaikul A, Davis B, Lohman K, Joon AY, Smith AV, Grove ML, Zanoni P, Redon V, Demissie S, Lawson K, Peters U, Carlson C, Jackson RD, Ryckman KK, Mackey RH, Robinson JG, Siscovick DS, Schreiner PJ, Mychaleckyj JC, Pankow JS, Hofman A, Uitterlinden AG, Harris TB, Taylor KD, Stafford JM, Reynolds LM, Marioni RE, Dehghan A, Franco OH, Patel AP, Lu Y, Hindy G, Gottesman O, Bottinger EP, Melander O, Orho-Melander M, Loos RJ, Duga S, Merlini PA, Farrall M, Goel A, Asselta R, Girelli D, Martinelli N, Shah SH, Kraus WE, Li M, Rader DJ, Reilly MP, McPherson R, Watkins H, Ardissino D, Zhang Q, Wang J, Tsai MY, Taylor HA, Correa A, Griswold ME, Lange LA, Starr JM, Rudan I, Eiriksdottir G, Launer LJ, Ordovas JM, Levy D, Chen YD, Reiner AP, Hayward C, Polasek O, Deary IJ, Borecki IB, Liu Y, Gudnason V, Wilson JG, van Duijn CM, Kooperberg C, Rich SS, Psaty BM, Rotter JI, O'Donnell CJ, Rice K, Boerwinkle E, Kathiresan S, Cupples LA. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014 Feb 06; 94(2):223-32. PMID: 24507774; PMCID: PMC3928662.
  615. Oei L, Estrada K, Duncan EL, Christiansen C, Liu CT, Langdahl BL, Obermayer-Pietsch B, Riancho JA, Prince RL, van Schoor NM, McCloskey E, Hsu YH, Evangelou E, Ntzani E, Evans DM, Alonso N, Husted LB, Valero C, Hernandez JL, Lewis JR, Kaptoge SK, Zhu K, Cupples LA, Medina-Gómez C, Vandenput L, Kim GS, Hun Lee S, Castaño-Betancourt MC, Oei EH, Martinez J, Daroszewska A, van der Klift M, Mellström D, Herrera L, Karlsson MK, Hofman A, Ljunggren Ö, Pols HA, Stolk L, van Meurs JB, Ioannidis JP, Zillikens MC, Lips P, Karasik D, Uitterlinden AG, Styrkarsdottir U, Brown MA, Koh JM, Richards JB, Reeve J, Ohlsson C, Ralston SH, Kiel DP, Rivadeneira F. Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus. Bone. 2014 Feb; 59:20-7. PMID: 24516880; PMCID: PMC4102322.
  616. Cents RA, Kok R, Tiemeier H, Lucassen N, Székely E, Bakermans-Kranenburg MJ, Hofman A, Jaddoe VW, van IJzendoorn MH, Verhulst FC, Lambregtse-van den Berg MP. Variations in maternal 5-HTTLPR affect observed sensitive parenting. J Child Psychol Psychiatry. 2014 Sep; 55(9):1025-32. PMID: 24484301.
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  617. Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dörr M, Ozaki K, Smith AV, Müller-Nurasyid M, Walter S, Agarwal SK, Bis JC, Brody JA, Chen LY, Everett BM, Ford I, Franco OH, Harris TB, Hofman A, Kääb S, Mahida S, Kathiresan S, Kubo M, Launer LJ, MacFarlane PW, Magnani JW, McKnight B, McManus DD, Peters A, Psaty BM, Rose LM, Rotter JI, Silbernagel G, Smith JD, Sotoodehnia N, Stott DJ, Taylor KD, Tomaschitz A, Tsunoda T, Uitterlinden AG, Van Wagoner DR, Völker U, Völzke H, Murabito JM, Sinner MF, Gudnason V, Felix SB, März W, Chung M, Albert CM, Stricker BH, Tanaka T, Heckbert SR, Jukema JW, Alonso A, Benjamin EJ, Ellinor PT. Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. J Am Coll Cardiol. 2014 Apr 01; 63(12):1200-1210. PMID: 24486271; PMCID: PMC4009240.
  618. Selwaness M, van den Bouwhuijsen Q, Mattace-Raso FU, Verwoert GC, Hofman A, Franco OH, Witteman JC, van der Lugt A, Vernooij MW, Wentzel JJ. Arterial stiffness is associated with carotid intraplaque hemorrhage in the general population: the Rotterdam study. Arterioscler Thromb Vasc Biol. 2014 Apr; 34(4):927-32. PMID: 24482373.
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  619. Godoy GA, Korevaar TI, Peeters RP, Hofman A, de Rijke YB, Bongers-Schokking JJ, Tiemeier H, Jaddoe VW, Gaillard R. Maternal thyroid hormones during pregnancy, childhood adiposity and cardiovascular risk factors: the Generation R Study. Clin Endocrinol (Oxf). 2014 Jul; 81(1):117-25. PMID: 24386874.
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  620. Jaddoe VW, de Jonge LL, Hofman A, Franco OH, Steegers EA, Gaillard R. First trimester fetal growth restriction and cardiovascular risk factors in school age children: population based cohort study. BMJ. 2014 Jan 23; 348:g14. PMID: 24458585; PMCID: PMC3901421.
  621. Liebrechts-Akkerman G, Liu F, Lao O, Ooms AH, van Duijn K, Vermeulen M, Jaddoe VW, Hofman A, Engelberts AC, Kayser M. PHOX2B polyalanine repeat length is associated with sudden infant death syndrome and unclassified sudden infant death in the Dutch population. Int J Legal Med. 2014 Jul; 128(4):621-9. PMID: 24442913.
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  622. Székely E, Lucassen N, Tiemeier H, Bakermans-Kranenburg MJ, Van Ijzendoorn MH, Kok R, Jaddoe VW, Hofman A, Verhulst FC, Herba CM. Maternal depressive symptoms and sensitivity are related to young children's facial expression recognition: the Generation R Study. Dev Psychopathol. 2014 May; 26(2):333-45. PMID: 24439036.
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  623. Tromp II, Gaillard R, Kiefte-de Jong JC, Steegers EA, Jaddoe VW, Duijts L, Hofman A, de Jongste JC, Moll HA. Maternal hemoglobin levels during pregnancy and asthma in childhood: the Generation R Study. Ann Allergy Asthma Immunol. 2014 Mar; 112(3):263-5. PMID: 24439422.
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  624. Ibrahim-Verbaas CA, Fornage M, Bis JC, Choi SH, Psaty BM, Meigs JB, Rao M, Nalls M, Fontes JD, O'Donnell CJ, Kathiresan S, Ehret GB, Fox CS, Malik R, Dichgans M, Schmidt H, Lahti J, Heckbert SR, Lumley T, Rice K, Rotter JI, Taylor KD, Folsom AR, Boerwinkle E, Rosamond WD, Shahar E, Gottesman RF, Koudstaal PJ, Amin N, Wieberdink RG, Dehghan A, Hofman A, Uitterlinden AG, Destefano AL, Debette S, Xue L, Beiser A, Wolf PA, Decarli C, Ikram MA, Seshadri S, Mosley TH, Longstreth WT, van Duijn CM, Launer LJ. Predicting stroke through genetic risk functions: the CHARGE Risk Score Project. Stroke. 2014 Feb; 45(2):403-12. PMID: 24436238; PMCID: PMC3955258.
  625. Deelen J, Beekman M, Codd V, Trompet S, Broer L, Hägg S, Fischer K, Thijssen PE, Suchiman HE, Postmus I, Uitterlinden AG, Hofman A, de Craen AJ, Metspalu A, Pedersen NL, van Duijn CM, Jukema JW, Houwing-Duistermaat JJ, Samani NJ, Slagboom PE. Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers. Int J Epidemiol. 2014 Jun; 43(3):878-86. PMID: 24425829; PMCID: PMC4052133.
  626. Moayyeri A, Hsu YH, Karasik D, Estrada K, Xiao SM, Nielson C, Srikanth P, Giroux S, Wilson SG, Zheng HF, Smith AV, Pye SR, Leo PJ, Teumer A, Hwang JY, Ohlsson C, McGuigan F, Minster RL, Hayward C, Olmos JM, Lyytikäinen LP, Lewis JR, Swart KM, Masi L, Oldmeadow C, Holliday EG, Cheng S, van Schoor NM, Harvey NC, Kruk M, del Greco M F, Igl W, Trummer O, Grigoriou E, Luben R, Liu CT, Zhou Y, Oei L, Medina-Gomez C, Zmuda J, Tranah G, Brown SJ, Williams FM, Soranzo N, Jakobsdottir J, Siggeirsdottir K, Holliday KL, Hannemann A, Go MJ, Garcia M, Polasek O, Laaksonen M, Zhu K, Enneman AW, McEvoy M, Peel R, Sham PC, Jaworski M, Johansson Å, Hicks AA, Pludowski P, Scott R, Dhonukshe-Rutten RA, van der Velde N, Kähönen M, Viikari JS, Sievänen H, Raitakari OT, González-Macías J, Hernández JL, Mellström D, Ljunggren O, Cho YS, Völker U, Nauck M, Homuth G, Völzke H, Haring R, Brown MA, McCloskey E, Nicholson GC, Eastell R, Eisman JA, Jones G, Reid IR, Dennison EM, Wark J, Boonen S, Vanderschueren D, Wu FC, Aspelund T, Richards JB, Bauer D, Hofman A, Khaw KT, Dedoussis G, Obermayer-Pietsch B, Gyllensten U, Pramstaller PP, Lorenc RS, Cooper C, Kung AW, Lips P, Alen M, Attia J, Brandi ML, de Groot LC, Lehtimäki T, Riancho JA, Campbell H, Liu Y, Harris TB, Akesson K, Karlsson M, Lee JY, Wallaschofski H, Duncan EL, O'Neill TW, Gudnason V, Spector TD, Rousseau F, Orwoll E, Cummings SR, Wareham NJ, Rivadeneira F, Uitterlinden AG, Prince RL, Kiel DP, Reeve J, Kaptoge SK. Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium. Hum Mol Genet. 2014 Jun 01; 23(11):3054-68. PMID: 24430505; PMCID: PMC4038791.
  627. Székely E, Tiemeier H, Jansen PW, Jaddoe VW, Hofman A, Verhulst FC, Herba CM. Maternal depressive symptoms are associated with low fearfulness in preschoolers. J Clin Child Adolesc Psychol. 2014; 43(5):791-8. PMID: 24400706.
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  628. de Bruijn RF, Akoudad S, Cremers LG, Hofman A, Niessen WJ, van der Lugt A, Koudstaal PJ, Vernooij MW, Ikram MA. Determinants, MRI correlates, and prognosis of mild cognitive impairment: the Rotterdam Study. J Alzheimers Dis. 2014; 42 Suppl 3:S239-49. PMID: 24825566.
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  629. de Bruijn RF, Janssen JA, Brugts MP, van Duijn CM, Hofman A, Koudstaal PJ, Ikram MA. Insulin-like growth factor-I receptor stimulating activity is associated with dementia. J Alzheimers Dis. 2014; 42(1):137-42. PMID: 24820016.
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  630. Loth DW, Brusselle GG, Lahousse L, Hofman A, Leufkens HG, Stricker BH. ß-Adrenoceptor blockers and pulmonary function in the general population: the Rotterdam Study. Br J Clin Pharmacol. 2014 Jan; 77(1):190-200. PMID: 23772842; PMCID: PMC3895360.
  631. de Keyser CE, Peters BJ, Becker ML, Visser LE, Uitterlinden AG, Klungel OH, Verstuyft C, Hofman A, Maitland-van der Zee AH, Stricker BH. The SLCO1B1 c.521T>C polymorphism is associated with dose decrease or switching during statin therapy in the Rotterdam Study. Pharmacogenet Genomics. 2014 Jan; 24(1):43-51. PMID: 24263182.
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  632. Gaillard R, Steegers EA, Duijts L, Felix JF, Hofman A, Franco OH, Jaddoe VW. Childhood cardiometabolic outcomes of maternal obesity during pregnancy: the Generation R Study. Hypertension. 2014 Apr; 63(4):683-91. PMID: 24379180.
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  633. van Kempen BJ, Ferket BS, Kavousi M, Leening MJ, Steyerberg EW, Ikram MA, Witteman JC, Hofman A, Franco OH, Hunink MG. Performance of Framingham cardiovascular disease (CVD) predictions in the Rotterdam Study taking into account competing risks and disentangling CVD into coronary heart disease (CHD) and stroke. Int J Cardiol. 2014 Feb 15; 171(3):413-8. PMID: 24438922.
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  634. van der Voort EA, Koehler EM, Dowlatshahi EA, Hofman A, Stricker BH, Janssen HL, Schouten JN, Nijsten T. Psoriasis is independently associated with nonalcoholic fatty liver disease in patients 55 years old or older: Results from a population-based study. J Am Acad Dermatol. 2014 Mar; 70(3):517-24. PMID: 24373781.
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  635. Oei L, Hsu YH, Styrkarsdottir U, Eussen BH, de Klein A, Peters MJ, Halldorsson B, Liu CT, Alonso N, Kaptoge SK, Thorleifsson G, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Kruk M, Lewis JR, Patel MS, Scollen S, Svensson O, Trompet S, van Schoor NM, Zhu K, Buckley BM, Cooper C, Ford I, Goltzman D, González-Macías J, Langdahl BL, Leslie WD, Lips P, Lorenc RS, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Slagboom PE, Garcia-Ibarbia C, Ingvarsson T, Johannsdottir H, Luben R, Medina-Gómez C, Arp P, Nandakumar K, Palsson ST, Sigurdsson G, van Meurs JB, Zhou Y, Hofman A, Jukema JW, Pols HA, Prince RL, Cupples LA, Marshall CR, Pinto D, Sato D, Scherer SW, Reeve J, Thorsteinsdottir U, Karasik D, Richards JB, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F, Estrada K. A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. J Med Genet. 2014 Feb; 51(2):122-31. PMID: 24343915.
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  636. Bouwland-Both MI, van Mil NH, Stolk L, Eilers PH, Verbiest MM, Heijmans BT, Tiemeier H, Hofman A, Steegers EA, Jaddoe VW, Steegers-Theunissen RP. DNA methylation of IGF2DMR and H19 is associated with fetal and infant growth: the generation R study. PLoS One. 2013; 8(12):e81731. PMID: 24349121; PMCID: PMC3861253.
  637. Fernandes CP, Christoforou A, Giddaluru S, Ersland KM, Djurovic S, Mattheisen M, Lundervold AJ, Reinvang I, Nöthen MM, Rietschel M, Ophoff RA, Hofman A, Uitterlinden AG, Werge T, Cichon S, Espeseth T, Andreassen OA, Steen VM, Le Hellard S. A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder. PLoS One. 2013; 8(12):e81052. PMID: 24349030; PMCID: PMC3861303.
  638. van der Valk RJ, Duijts L, Timpson NJ, Salam MT, Standl M, Curtin JA, Genuneit J, Kerhof M, Kreiner-Møller E, Cáceres A, Gref A, Liang LL, Taal HR, Bouzigon E, Demenais F, Nadif R, Ober C, Thompson EE, Estrada K, Hofman A, Uitterlinden AG, van Duijn C, Rivadeneira F, Li X, Eckel SP, Berhane K, Gauderman WJ, Granell R, Evans DM, St Pourcain B, McArdle W, Kemp JP, Smith GD, Tiesler CM, Flexeder C, Simpson A, Murray CS, Fuchs O, Postma DS, Bønnelykke K, Torrent M, Andersson M, Sleiman P, Hakonarson H, Cookson WO, Moffatt MF, Paternoster L, Melén E, Sunyer J, Bisgaard H, Koppelman GH, Ege M, Custovic A, Heinrich J, Gilliland FD, Henderson AJ, Jaddoe VW, de Jongste JC. Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. J Allergy Clin Immunol. 2014 Jul; 134(1):46-55. PMID: 24315451; PMCID: PMC4334587.
  639. Chain AS, Dieleman JP, van Noord C, Hofman A, Stricker BH, Danhof M, Sturkenboom MC, Della Pasqua O. Not-in-trial simulation I: Bridging cardiovascular risk from clinical trials to real-life conditions. Br J Clin Pharmacol. 2013 Dec; 76(6):964-72. PMID: 23617533; PMCID: PMC3845320.
  640. Driessen LM, Kiefte-de Jong JC, Wijtzes A, de Vries SI, Jaddoe VW, Hofman A, Raat H, Moll HA. Preschool physical activity and functional constipation: the Generation R study. J Pediatr Gastroenterol Nutr. 2013 Dec; 57(6):768-74. PMID: 23857342.
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  641. Kok R, Linting M, Bakermans-Kranenburg MJ, van Ijzendoorn MH, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Maternal sensitivity and internalizing problems: evidence from two longitudinal studies in early childhood. Child Psychiatry Hum Dev. 2013 Dec; 44(6):751-65. PMID: 23408268.
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  642. Wang JJ, Buitendijk GH, Rochtchina E, Lee KE, Klein BE, van Duijn CM, Flood VM, Meuer SM, Attia J, Myers C, Holliday EG, Tan AG, Smith WT, Iyengar SK, de Jong PT, Hofman A, Vingerling JR, Mitchell P, Klein R, Klaver CC. Genetic susceptibility, dietary antioxidants, and long-term incidence of age-related macular degeneration in two populations. Ophthalmology. 2014 Mar; 121(3):667-75. PMID: 24290803.
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  643. Hofman A, Darwish Murad S, van Duijn CM, Franco OH, Goedegebure A, Ikram MA, Klaver CC, Nijsten TE, Peeters RP, Stricker BH, Tiemeier HW, Uitterlinden AG, Vernooij MW. The Rotterdam Study: 2014 objectives and design update. Eur J Epidemiol. 2013 Nov; 28(11):889-926. PMID: 24258680.
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  644. Liu F, Hendriks AE, Ralf A, Boot AM, Benyi E, Sävendahl L, Oostra BA, van Duijn C, Hofman A, Rivadeneira F, Uitterlinden AG, Drop SL, Kayser M. Common DNA variants predict tall stature in Europeans. Hum Genet. 2014 May; 133(5):587-97. PMID: 24253421.
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  645. Koehler EM, Sanna D, Hansen BE, van Rooij FJ, Heeringa J, Hofman A, Tiemeier H, Stricker BH, Schouten JN, Janssen HL. Serum liver enzymes are associated with all-cause mortality in an elderly population. Liver Int. 2014 Feb; 34(2):296-304. PMID: 24219360.
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  646. Sedaghat S, Hoorn EJ, van Rooij FJ, Hofman A, Franco OH, Witteman JC, Dehghan A. Serum uric acid and chronic kidney disease: the role of hypertension. PLoS One. 2013; 8(11):e76827. PMID: 24265674; PMCID: PMC3827035.
  647. Hafkamp-de Groen E, Sonnenschein-van der Voort AM, Mackenbach JP, Duijts L, Jaddoe VW, Moll HA, Hofman A, de Jongste JC, Raat H. Socioeconomic and sociodemographic factors associated with asthma related outcomes in early childhood: the Generation R Study. PLoS One. 2013; 8(11):e78266. PMID: 24244299; PMCID: PMC3823924.
  648. Portegies ML, de Bruijn RF, Hofman A, Koudstaal PJ, Ikram MA. Cerebral vasomotor reactivity and risk of mortality: the Rotterdam Study. Stroke. 2014 Jan; 45(1):42-7. PMID: 24203842.
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  649. van Mil NH, Steegers-Theunissen RP, Bouwland-Both MI, Verbiest MM, Rijlaarsdam J, Hofman A, Steegers EA, Heijmans BT, Jaddoe VW, Verhulst FC, Stolk L, Eilers PH, Uitterlinden AG, Tiemeier H. DNA methylation profiles at birth and child ADHD symptoms. J Psychiatr Res. 2014 Feb; 49:51-9. PMID: 24290898.
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  650. den Hollander WJ, Holster IL, den Hoed CM, van Deurzen F, van Vuuren AJ, Jaddoe VW, Hofman A, Perez Perez GI, Blaser MJ, Moll HA, Kuipers EJ. Ethnicity is a strong predictor for Helicobacter pylori infection in young women in a multi-ethnic European city. J Gastroenterol Hepatol. 2013 Nov; 28(11):1705-11. PMID: 23808840; PMCID: PMC3822168.
  651. Akoudad S, de Groot M, Koudstaal PJ, van der Lugt A, Niessen WJ, Hofman A, Ikram MA, Vernooij MW. Cerebral microbleeds are related to loss of white matter structural integrity. Neurology. 2013 Nov 26; 81(22):1930-7. PMID: 24174590.
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  652. Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F, Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannefelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltuenen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet. 2013 Dec; 45(12):1452-8. PMID: 24162737; PMCID: PMC3896259.
  653. Oei L, Estrada K, Duncan EL, Christiansen C, Liu CT, Langdahl BL, Obermayer-Pietsch B, Riancho JA, Prince RL, van Schoor NM, McCloskey E, Hsu YH, Evangelou E, Ntzani E, Evans DM, Alonso N, Husted LB, Valero C, Hernandez JL, Lewis JR, Kaptoge SK, Zhu K, Cupples LA, Medina-Gómez C, Vandenput L, Kim GS, Lee SH, Castaño-Betancourt MC, Oei EH, Martinez J, Daroszewska A, van der Klift M, Mellström D, Herrera L, Karlsson MK, Hofman A, Ljunggren O, Pols HA, Stolk L, van Meurs JB, Ioannidis JP, Zillikens MC, Lips P, Karasik D, Uitterlinden AG, Styrkarsdottir U, Brown MA, Koh JM, Richards JB, Reeve J, Ohlsson C, Ralston SH, Kiel DP, Rivadeneira F. Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition. Bone. 2013 Oct 25. PMID: 24513584.
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  654. Iglesias AI, Springelkamp H, van der Linde H, Severijnen LA, Amin N, Oostra B, Kockx CE, van den Hout MC, van Ijcken WF, Hofman A, Uitterlinden AG, Verdijk RM, Klaver CC, Willemsen R, van Duijn CM. Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation-differentiation balance early in life and optic nerve degeneration at old age. Hum Mol Genet. 2014 Mar 01; 23(5):1320-32. PMID: 24150847.
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  655. Verhoeven VJ, Buitendijk GH, Rivadeneira F, Uitterlinden AG, Vingerling JR, Hofman A, Klaver CC. Education influences the role of genetics in myopia. Eur J Epidemiol. 2013 Dec; 28(12):973-80. PMID: 24142238; PMCID: PMC3898347.
  656. Gaillard R, Steegers EA, Tiemeier H, Hofman A, Jaddoe VW. Placental vascular dysfunction, fetal and childhood growth, and cardiovascular development: the generation R study. Circulation. 2013 Nov 12; 128(20):2202-10. PMID: 24135069.
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  657. Buitendijk GH, Rochtchina E, Myers C, van Duijn CM, Lee KE, Klein BE, Meuer SM, de Jong PT, Holliday EG, Tan AG, Uitterlinden AG, Sivakumaran TA, Sivakumaran TS, Attia J, Hofman A, Mitchell P, Vingerling JR, Iyengar SK, Janssens AC, Wang JJ, Klein R, Klaver CC. Prediction of age-related macular degeneration in the general population: the Three Continent AMD Consortium. Ophthalmology. 2013 Dec; 120(12):2644-55. PMID: 24120328; PMCID: PMC3986722.
  658. Loehrer E, Ikram MA, Akoudad S, Vrooman HA, van der Lugt A, Niessen WJ, Hofman A, Vernooij MW. Apolipoprotein E genotype influences spatial distribution of cerebral microbleeds. Neurobiol Aging. 2014 Apr; 35(4):899-905. PMID: 24119543.
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  659. Medici M, Ghassabian A, Visser W, de Muinck Keizer-Schrama SM, Jaddoe VW, Visser WE, Hooijkaas H, Hofman A, Steegers EA, Bongers-Schokking JJ, Ross HA, Tiemeier H, Visser TJ, de Rijke YB, Peeters RP. Women with high early pregnancy urinary iodine levels have an increased risk of hyperthyroid newborns: the population-based Generation R Study. Clin Endocrinol (Oxf). 2014 Apr; 80(4):598-606. PMID: 23992400.
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  660. El Marroun H, Schmidt MN, Franken IH, Jaddoe VW, Hofman A, van der Lugt A, Verhulst FC, Tiemeier H, White T. Prenatal tobacco exposure and brain morphology: a prospective study in young children. Neuropsychopharmacology. 2014 Mar; 39(4):792-800. PMID: 24096296; PMCID: PMC3924517.
  661. Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Do R, Donnelly LA, Ehret GB, Esko T, Feitosa MF, Ferreira T, Fischer K, Fontanillas P, Fraser RM, Freitag DF, Gurdasani D, Heikkilä K, Hyppönen E, Isaacs A, Jackson AU, Johansson Å, Johnson T, Kaakinen M, Kettunen J, Kleber ME, Li X, Luan J, Lyytikäinen LP, Magnusson PKE, Mangino M, Mihailov E, Montasser ME, Müller-Nurasyid M, Nolte IM, O'Connell JR, Palmer CD, Perola M, Petersen AK, Sanna S, Saxena R, Service SK, Shah S, Shungin D, Sidore C, Song C, Strawbridge RJ, Surakka I, Tanaka T, Teslovich TM, Thorleifsson G, Van den Herik EG, Voight BF, Volcik KA, Waite LL, Wong A, Wu Y, Zhang W, Absher D, Asiki G, Barroso I, Been LF, Bolton JL, Bonnycastle LL, Brambilla P, Burnett MS, Cesana G, Dimitriou M, Doney ASF, Döring A, Elliott P, Epstein SE, Ingi Eyjolfsson G, Gigante B, Goodarzi MO, Grallert H, Gravito ML, Groves CJ, Hallmans G, Hartikainen AL, Hayward C, Hernandez D, Hicks AA, Holm H, Hung YJ, Illig T, Jones MR, Kaleebu P, Kastelein JJP, Khaw KT, Kim E, Klopp N, Komulainen P, Kumari M, Langenberg C, Lehtimäki T, Lin SY, Lindström J, Loos RJF, Mach F, McArdle WL, Meisinger C, Mitchell BD, Müller G, Nagaraja R, Narisu N, Nieminen TVM, Nsubuga RN, Olafsson I, Ong KK, Palotie A, Papamarkou T, Pomilla C, Pouta A, Rader DJ, Reilly MP, Ridker PM, Rivadeneira F, Rudan I, Ruokonen A, Samani N, Scharnagl H, Seeley J, Silander K, Stancáková A, Stirrups K, Swift AJ, Tiret L, Uitterlinden AG, van Pelt LJ, Vedantam S, Wainwright N, Wijmenga C, Wild SH, Willemsen G, Wilsgaard T, Wilson JF, Young EH, Zhao JH, Adair LS, Arveiler D, Assimes TL, Bandinelli S, Bennett F, Bochud M, Boehm BO, Boomsma DI, Borecki IB, Bornstein SR, Bovet P, Burnier M, Campbell H, Chakravarti A, Chambers JC, Chen YI, Collins FS, Cooper RS, Danesh J, Dedoussis G, de Faire U, Feranil AB, Ferrières J, Ferrucci L, Freimer NB, Gieger C, Groop LC, Gudnason V, Gyllensten U, Hamsten A, Harris TB, Hingorani A, Hirschhorn JN, Hofman A, Hovingh GK, Hsiung CA, Humphries SE, Hunt SC, Hveem K, Iribarren C, Järvelin MR, Jula A, Kähönen M, Kaprio J, Kesäniemi A, Kivimaki M, Kooner JS, Koudstaal PJ, Krauss RM, Kuh D, Kuusisto J, Kyvik KO, Laakso M, Lakka TA, Lind L, Lindgren CM, Martin NG, März W, McCarthy MI, McKenzie CA, Meneton P, Metspalu A, Moilanen L, Morris AD, Munroe PB, Njølstad I, Pedersen NL, Power C, Pramstaller PP, Price JF, Psaty BM, Quertermous T, Rauramaa R, Saleheen D, Salomaa V, Sanghera DK, Saramies J, Schwarz PEH, Sheu WH, Shuldiner AR, Siegbahn A, Spector TD, Stefansson K, Strachan DP, Tayo BO, Tremoli E, Tuomilehto J, Uusitupa M, van Duijn CM, Vollenweider P, Wallentin L, Wareham NJ, Whitfield JB, Wolffenbuttel BHR, Ordovas JM, Boerwinkle E, Palmer CNA, Thorsteinsdottir U, Chasman DI, Rotter JI, Franks PW, Ripatti S, Cupples LA, Sandhu MS, Rich SS, Boehnke M, Deloukas P, Kathiresan S, Mohlke KL, Ingelsson E, Abecasis GR. Discovery and refinement of loci associated with lipid levels. Nat Genet. 2013 Nov; 45(11):1274-1283. PMID: 24097068; PMCID: PMC3838666.
  662. Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Donnelly LA, Ehret GB, Esko T, Feitosa MF, Ferreira T, Fischer K, Fontanillas P, Fraser RM, Freitag DF, Gurdasani D, Heikkilä K, Hyppönen E, Isaacs A, Jackson AU, Johansson A, Johnson T, Kaakinen M, Kettunen J, Kleber ME, Li X, Luan J, Lyytikäinen LP, Magnusson PK, Mangino M, Mihailov E, Montasser ME, Müller-Nurasyid M, Nolte IM, O'Connell JR, Palmer CD, Perola M, Petersen AK, Sanna S, Saxena R, Service SK, Shah S, Shungin D, Sidore C, Song C, Strawbridge RJ, Surakka I, Tanaka T, Teslovich TM, Thorleifsson G, Van den Herik EG, Voight BF, Volcik KA, Waite LL, Wong A, Wu Y, Zhang W, Absher D, Asiki G, Barroso I, Been LF, Bolton JL, Bonnycastle LL, Brambilla P, Burnett MS, Cesana G, Dimitriou M, Doney AS, Döring A, Elliott P, Epstein SE, Eyjolfsson GI, Gigante B, Goodarzi MO, Grallert H, Gravito ML, Groves CJ, Hallmans G, Hartikainen AL, Hayward C, Hernandez D, Hicks AA, Holm H, Hung YJ, Illig T, Jones MR, Kaleebu P, Kastelein JJ, Khaw KT, Kim E, Klopp N, Komulainen P, Kumari M, Langenberg C, Lehtimäki T, Lin SY, Lindström J, Loos RJ, Mach F, McArdle WL, Meisinger C, Mitchell BD, Müller G, Nagaraja R, Narisu N, Nieminen TV, Nsubuga RN, Olafsson I, Ong KK, Palotie A, Papamarkou T, Pomilla C, Pouta A, Rader DJ, Reilly MP, Ridker PM, Rivadeneira F, Rudan I, Ruokonen A, Samani N, Scharnagl H, Seeley J, Silander K, Stancáková A, Stirrups K, Swift AJ, Tiret L, Uitterlinden AG, van Pelt LJ, Vedantam S, Wainwright N, Wijmenga C, Wild SH, Willemsen G, Wilsgaard T, Wilson JF, Young EH, Zhao JH, Adair LS, Arveiler D, Assimes TL, Bandinelli S, Bennett F, Bochud M, Boehm BO, Boomsma DI, Borecki IB, Bornstein SR, Bovet P, Burnier M, Campbell H, Chakravarti A, Chambers JC, Chen YD, Collins FS, Cooper RS, Danesh J, Dedoussis G, de Faire U, Feranil AB, Ferrières J, Ferrucci L, Freimer NB, Gieger C, Groop LC, Gudnason V, Gyllensten U, Hamsten A, Harris TB, Hingorani A, Hirschhorn JN, Hofman A, Hovingh GK, Hsiung CA, Humphries SE, Hunt SC, Hveem K, Iribarren C, Järvelin MR, Jula A, Kähönen M, Kaprio J, Kesäniemi A, Kivimaki M, Kooner JS, Koudstaal PJ, Krauss RM, Kuh D, Kuusisto J, Kyvik KO, Laakso M, Lakka TA, Lind L, Lindgren CM, Martin NG, März W, McCarthy MI, McKenzie CA, Meneton P, Metspalu A, Moilanen L, Morris AD, Munroe PB, Njølstad I, Pedersen NL, Power C, Pramstaller PP, Price JF, Psaty BM, Quertermous T, Rauramaa R, Saleheen D, Salomaa V, Sanghera DK, Saramies J, Schwarz PE, Sheu WH, Shuldiner AR, Siegbahn A, Spector TD, Stefansson K, Strachan DP, Tayo BO, Tremoli E, Tuomilehto J, Uusitupa M, van Duijn CM, Vollenweider P, Wallentin L, Wareham NJ, Whitfield JB, Wolffenbuttel BH, Altshuler D, Ordovas JM, Boerwinkle E, Palmer CN, Thorsteinsdottir U, Chasman DI, Rotter JI, Franks PW, Ripatti S, Cupples LA, Sandhu MS, Rich SS, Boehnke M, Deloukas P, Mohlke KL, Ingelsson E, Abecasis GR, Daly MJ, Neale BM, Kathiresan S. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet. 2013 Nov; 45(11):1345-52. PMID: 24097064; PMCID: PMC3904346.
  663. van Dijk FS, Zillikens MC, Micha D, Riessland M, Marcelis CL, de Die-Smulders CE, Milbradt J, Franken AA, Harsevoort AJ, Lichtenbelt KD, Pruijs HE, Rubio-Gozalbo ME, Zwertbroek R, Moutaouakil Y, Egthuijsen J, Hammerschmidt M, Bijman R, Semeins CM, Bakker AD, Everts V, Klein-Nulend J, Campos-Obando N, Hofman A, te Meerman GJ, Verkerk AJ, Uitterlinden AG, Maugeri A, Sistermans EA, Waisfisz Q, Meijers-Heijboer H, Wirth B, Simon ME, Pals G. PLS3 mutations in X-linked osteoporosis with fractures. N Engl J Med. 2013 Oct 17; 369(16):1529-36. PMID: 24088043.
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  664. Dehghan A, Leening MJ, Solouki AM, Boersma E, Deckers JW, van Herpen G, Heeringa J, Hofman A, Kors JA, Franco OH, Ikram MA, Witteman JC. Comparison of prognosis in unrecognized versus recognized myocardial infarction in men versus women >55 years of age (from the Rotterdam Study). Am J Cardiol. 2014 Jan 01; 113(1):1-6. PMID: 24216125.
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  665. de Jonge LL, Langhout MA, Taal HR, Franco OH, Raat H, Hofman A, van Osch-Gevers L, Jaddoe VW. Infant feeding patterns are associated with cardiovascular structures and function in childhood. J Nutr. 2013 Dec; 143(12):1959-65. PMID: 24089417.
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  666. Ikram MK, de Jong FJ, Vernooij MW, Hofman A, Niessen WJ, van der Lugt A, Klaver CC, Ikram MA. Retinal vascular calibers associate differentially with cerebral gray matter and white matter atrophy. Alzheimer Dis Assoc Disord. 2013 Oct-Dec; 27(4):351-5. PMID: 23632264.
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  667. Oei L, Ly F, El Saddy S, Makurthou AA, Hofman A, van Rooij FJ, Uitterlinden AG, Zillikens MC, Rivadeneira F, Oei EH. Multi-functionality of computer-aided quantitative vertebral fracture morphometry analyses. Quant Imaging Med Surg. 2013 Oct; 3(5):249-55. PMID: 24273742; PMCID: PMC3834208.
  668. Taal HR, de Jonge LL, van Osch-Gevers L, Steegers EA, Hofman A, Helbing WA, van der Heijden AJ, Jaddoe VW. Parental smoking during pregnancy and cardiovascular structures and function in childhood: the Generation R Study. Int J Epidemiol. 2013 Oct; 42(5):1371-80. PMID: 24159077.
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  669. Lahousse L, Vernooij MW, Darweesh SK, Akoudad S, Loth DW, Joos GF, Hofman A, Stricker BH, Ikram MA, Brusselle GG. Chronic obstructive pulmonary disease and cerebral microbleeds. The Rotterdam Study. Am J Respir Crit Care Med. 2013 Oct 01; 188(7):783-8. PMID: 23885754.
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  670. Felix JF, Voortman T, van den Hooven EH, Sajjad A, Leermakers ET, Tharner A, Kiefte-de Jong JC, Duijts L, Verhulst FC, de Jongste JC, Tiemeier H, Hofman A, Rivadeneira F, Moll HA, Raat H, Jaddoe VW, Franco OH. Health in children: a conceptual framework for use in healthy ageing research. Maturitas. 2014 Jan; 77(1):47-51. PMID: 24139819.
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  671. Bouthoorn SH, Van Lenthe FJ, De Jonge LL, Hofman A, Van Osch-Gevers L, Jaddoe VW, Raat H. Maternal educational level and blood pressure, aortic stiffness, cardiovascular structure and functioning in childhood: the generation R study. Am J Hypertens. 2014 Jan; 27(1):89-98. PMID: 24077827.
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  672. Darweesh SK, Leening MJ, Akoudad S, Loth DW, Hofman A, Ikram MA, Vernooij MW, Stricker BH. Clopidogrel use is associated with an increased prevalence of cerebral microbleeds in a stroke-free population: the Rotterdam study. J Am Heart Assoc. 2013 Sep 26; 2(5):e000359. PMID: 24072532; PMCID: PMC3835244.
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  674. van den Hooven EH, de Jonge LL, Kiefte-de Jong JC, Raat H, Villamor E, Hofman A, Felix JF, Jaddoe VW, Moll HA, Franco OH. Infant macronutrient composition is associated with differences in cardiovascular structures and function in childhood. J Nutr. 2013 Dec; 143(12):1989-98. PMID: 24068791.
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  676. Zhan X, Larson DE, Wang C, Koboldt DC, Sergeev YV, Fulton RS, Fulton LL, Fronick CC, Branham KE, Bragg-Gresham J, Jun G, Hu Y, Kang HM, Liu D, Othman M, Brooks M, Ratnapriya R, Boleda A, Grassmann F, von Strachwitz C, Olson LM, Buitendijk GH, Hofman A, van Duijn CM, Cipriani V, Moore AT, Shahid H, Jiang Y, Conley YP, Morgan DJ, Kim IK, Johnson MP, Cantsilieris S, Richardson AJ, Guymer RH, Luo H, Ouyang H, Licht C, Pluthero FG, Zhang MM, Zhang K, Baird PN, Blangero J, Klein ML, Farrer LA, DeAngelis MM, Weeks DE, Gorin MB, Yates JR, Klaver CC, Pericak-Vance MA, Haines JL, Weber BH, Wilson RK, Heckenlively JR, Chew EY, Stambolian D, Mardis ER, Swaroop A, Abecasis GR. Identification of a rare coding variant in complement 3 associated with age-related macular degeneration. Nat Genet. 2013 Nov; 45(11):1375-9. PMID: 24036949; PMCID: PMC3812337.
  677. Korevaar TI, Schalekamp-Timmermans S, de Rijke YB, Visser WE, Visser W, de Muinck Keizer-Schrama SM, Hofman A, Ross HA, Hooijkaas H, Tiemeier H, Bongers-Schokking JJ, Jaddoe VW, Visser TJ, Steegers EA, Medici M, Peeters RP. Hypothyroxinemia and TPO-antibody positivity are risk factors for premature delivery: the generation R study. J Clin Endocrinol Metab. 2013 Nov; 98(11):4382-90. PMID: 24037884.
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  678. Kok R, Lucassen N, Bakermans-Kranenburg MJ, van IJzendoorn MH, Ghassabian A, Roza SJ, Govaert P, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Parenting, corpus callosum, and executive function in preschool children. Child Neuropsychol. 2014; 20(5):583-606. PMID: 24028215.
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  679. Parsa A, Fuchsberger C, Köttgen A, O'Seaghdha CM, Pattaro C, de Andrade M, Chasman DI, Teumer A, Endlich K, Olden M, Chen MH, Tin A, Kim YJ, Taliun D, Li M, Feitosa M, Gorski M, Yang Q, Hundertmark C, Foster MC, Glazer N, Isaacs A, Rao M, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Couraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Hofer E, Hu F, Demirkan A, Oostra BA, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Döring A, Wichmann HE, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, van Duijn CM, Borecki I, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Bochud M, Heid IM, Siscovick DS, Fox CS, Kao WL, Böger CA. Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol. 2013 Dec; 24(12):2105-17. PMID: 24029420; PMCID: PMC3839542.
  680. Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, Christiansen MW, Fairfax BP, Schramm K, Powell JE, Zhernakova A, Zhernakova DV, Veldink JH, Van den Berg LH, Karjalainen J, Withoff S, Uitterlinden AG, Hofman A, Rivadeneira F, Hoen PAC', Reinmaa E, Fischer K, Nelis M, Milani L, Melzer D, Ferrucci L, Singleton AB, Hernandez DG, Nalls MA, Homuth G, Nauck M, Radke D, Völker U, Perola M, Salomaa V, Brody J, Suchy-Dicey A, Gharib SA, Enquobahrie DA, Lumley T, Montgomery GW, Makino S, Prokisch H, Herder C, Roden M, Grallert H, Meitinger T, Strauch K, Li Y, Jansen RC, Visscher PM, Knight JC, Psaty BM, Ripatti S, Teumer A, Frayling TM, Metspalu A, van Meurs JBJ, Franke L. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat Genet. 2013 Oct; 45(10):1238-1243. PMID: 24013639; PMCID: PMC3991562.
  681. Makurthou AA, Oei L, El Saddy S, Breda SJ, Castaño-Betancourt MC, Hofman A, van Meurs JB, Uitterlinden AG, Rivadeneira F, Oei EH. Scheuermann disease: evaluation of radiological criteria and population prevalence. Spine (Phila Pa 1976). 2013 Sep 01; 38(19):1690-4. PMID: 24509552.
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  682. Luijk MP, Mileva-Seitz VR, Jansen PW, van IJzendoorn MH, Jaddoe VW, Raat H, Hofman A, Verhulst FC, Tiemeier H. Ethnic differences in prevalence and determinants of mother-child bed-sharing in early childhood. Sleep Med. 2013 Nov; 14(11):1092-9. PMID: 23994270.
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  683. Evangelou E, Kerkhof HJ, Styrkarsdottir U, Ntzani EE, Bos SD, Esko T, Evans DS, Metrustry S, Panoutsopoulou K, Ramos YF, Thorleifsson G, Tsilidis KK, Arden N, Aslam N, Bellamy N, Birrell F, Blanco FJ, Carr A, Chapman K, Day-Williams AG, Deloukas P, Doherty M, Engström G, Helgadottir HT, Hofman A, Ingvarsson T, Jonsson H, Keis A, Keurentjes JC, Kloppenburg M, Lind PA, McCaskie A, Martin NG, Milani L, Montgomery GW, Nelissen RG, Nevitt MC, Nilsson PM, Ollier WE, Parimi N, Rai A, Ralston SH, Reed MR, Riancho JA, Rivadeneira F, Rodriguez-Fontenla C, Southam L, Thorsteinsdottir U, Tsezou A, Wallis GA, Wilkinson JM, Gonzalez A, Lane NE, Lohmander LS, Loughlin J, Metspalu A, Uitterlinden AG, Jonsdottir I, Stefansson K, Slagboom PE, Zeggini E, Meulenbelt I, Ioannidis JP, Spector TD, van Meurs JB, Valdes AM. A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip. Ann Rheum Dis. 2014 Dec; 73(12):2130-6. PMID: 23989986; PMCID: PMC4251181.
  684. Wijtzes AI, Jansen W, Jansen PW, Jaddoe VW, Hofman A, Raat H. Maternal educational level and preschool children's consumption of high-calorie snacks and sugar-containing beverages: mediation by the family food environment. Prev Med. 2013 Nov; 57(5):607-12. PMID: 23988496.
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  685. Hafkamp-de Groen E, Lingsma HF, Caudri D, Levie D, Wijga A, Koppelman GH, Duijts L, Jaddoe VW, Smit HA, Kerkhof M, Moll HA, Hofman A, Steyerberg EW, de Jongste JC, Raat H. Predicting asthma in preschool children with asthma-like symptoms: validating and updating the PIAMA risk score. J Allergy Clin Immunol. 2013 Dec; 132(6):1303-10. PMID: 23987795.
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  686. Krijthe BP, Heeringa J, Kors JA, Hofman A, Franco OH, Witteman JC, Stricker BH. Serum potassium levels and the risk of atrial fibrillation: the Rotterdam Study. Int J Cardiol. 2013 Oct 15; 168(6):5411-5. PMID: 24012173.
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  687. Luik AI, Zuurbier LA, Hofman A, Van Someren EJ, Tiemeier H. Stability and fragmentation of the activity rhythm across the sleep-wake cycle: the importance of age, lifestyle, and mental health. Chronobiol Int. 2013 Dec; 30(10):1223-30. PMID: 23971909.
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  688. Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Rudnicka AR, Trompet S, Mälarstig A, Baumert J, Bis JC, Guo X, Hottenga JJ, Shin SY, Lopez LM, Lahti J, Tanaka T, Yanek LR, Oudot-Mellakh T, Wilson JF, Navarro P, Huffman JE, Zemunik T, Redline S, Mehra R, Pulanic D, Rudan I, Wright AF, Kolcic I, Polasek O, Wild SH, Campbell H, Curb JD, Wallace R, Liu S, Eaton CB, Becker DM, Becker LC, Bandinelli S, Räikkönen K, Widen E, Palotie A, Fornage M, Green D, Gross M, Davies G, Harris SE, Liewald DC, Starr JM, Williams FM, Grant PJ, Spector TD, Strawbridge RJ, Silveira A, Sennblad B, Rivadeneira F, Uitterlinden AG, Franco OH, Hofman A, van Dongen J, Willemsen G, Boomsma DI, Yao J, Swords Jenny N, Haritunians T, McKnight B, Lumley T, Taylor KD, Rotter JI, Psaty BM, Peters A, Gieger C, Illig T, Grotevendt A, Homuth G, Völzke H, Kocher T, Goel A, Franzosi MG, Seedorf U, Clarke R, Steri M, Tarasov KV, Sanna S, Schlessinger D, Stott DJ, Sattar N, Buckley BM, Rumley A, Lowe GD, McArdle WL, Chen MH, Tofler GH, Song J, Boerwinkle E, Folsom AR, Rose LM, Franco-Cereceda A, Teichert M, Ikram MA, Mosley TH, Bevan S, Dichgans M, Rothwell PM, Sudlow CL, Hopewell JC, Chambers JC, Saleheen D, Kooner JS, Danesh J, Nelson CP, Erdmann J, Reilly MP, Kathiresan S, Schunkert H, Morange PE, Ferrucci L, Eriksson JG, Jacobs D, Deary IJ, Soranzo N, Witteman JC, de Geus EJ, Tracy RP, Hayward C, Koenig W, Cucca F, Jukema JW, Eriksson P, Seshadri S, Markus HS, Watkins H, Samani NJ, Wallaschofski H, Smith NL, Tregouet D, Ridker PM, Tang W, Strachan DP, Hamsten A, O'Donnell CJ. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 2013 Sep 17; 128(12):1310-24. PMID: 23969696; PMCID: PMC3842025.
  689. Flink IJ, Prins RG, Mackenbach JJ, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H, Raat H. Neighborhood ethnic diversity and behavioral and emotional problems in 3 year olds: results from the Generation R Study. PLoS One. 2013; 8(8):e70070. PMID: 23967068; PMCID: PMC3743872.
  690. Román GC, Ghassabian A, Bongers-Schokking JJ, Jaddoe VW, Hofman A, de Rijke YB, Verhulst FC, Tiemeier H. Association of gestational maternal hypothyroxinemia and increased autism risk. Ann Neurol. 2013 Nov; 74(5):733-42. PMID: 23943579.
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  691. Ringoot AP, Jansen PW, Steenweg-de Graaff J, Measelle JR, van der Ende J, Raat H, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Young children's self-reported emotional, behavioral, and peer problems: the Berkeley Puppet Interview. Psychol Assess. 2013 Dec; 25(4):1273-85. PMID: 23937536.
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  692. Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St Pourcain B, Kemp JP, McMahon G, Timpson NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, van Leeuwen EM, Wilson JF, Pennell CE, van Duijn CM, de Jong PT, Vingerling JR, Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M, Burdon KP, Craig JE, Iyengar SK, Igo RP, Lass JH, Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, Höhn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ, Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD, Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MK, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E, Tai ES, Fan Q, Xu L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, Pärssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CC, Wong TY, Saw SM, Baird PN. Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. Am J Hum Genet. 2013 Aug 08; 93(2):264-77. PMID: 24144296; PMCID: PMC3772747.
  693. Elfrink ME, Moll HA, Kiefte-de Jong JC, El Marroun H, Jaddoe VW, Hofman A, Stricker BH, ten Cate JM, Veerkamp JS. Is maternal use of medicines during pregnancy associated with deciduous molar hypomineralisation in the offspring? A prospective, population-based study. Drug Saf. 2013 Aug; 36(8):627-33. PMID: 23743695.
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  694. Noordam R, Aarts N, Hofman A, van Schaik RH, Stricker BH, Visser LE. Association between genetic variation in the ABCB1 gene and switching, discontinuation, and dosage of antidepressant therapy: results from the Rotterdam Study. J Clin Psychopharmacol. 2013 Aug; 33(4):546-50. PMID: 23771194.
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  695. Chowdhury R, Khan H, Heydon E, Shroufi A, Fahimi S, Moore C, Stricker B, Mendis S, Hofman A, Mant J, Franco OH. Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences. Eur Heart J. 2013 Oct; 34(38):2940-8. PMID: 23907142.
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  696. de Keyser CE, Becker ML, Uitterlinden AG, Hofman A, Lous JJ, Elens L, Visser LE, van Schaik RH, Stricker BH. Genetic variation in the PPARA gene is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study. Pharmacogenomics. 2013 Aug; 14(11):1295-304. PMID: 23930676.
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  697. Holmes MV, Simon T, Exeter HJ, Folkersen L, Asselbergs FW, Guardiola M, Cooper JA, Palmen J, Hubacek JA, Carruthers KF, Horne BD, Brunisholz KD, Mega JL, van Iperen EP, Li M, Leusink M, Trompet S, Verschuren JJ, Hovingh GK, Dehghan A, Nelson CP, Kotti S, Danchin N, Scholz M, Haase CL, Rothenbacher D, Swerdlow DI, Kuchenbaecker KB, Staines-Urias E, Goel A, van 't Hooft F, Gertow K, de Faire U, Panayiotou AG, Tremoli E, Baldassarre D, Veglia F, Holdt LM, Beutner F, Gansevoort RT, Navis GJ, Mateo Leach I, Breitling LP, Brenner H, Thiery J, Dallmeier D, Franco-Cereceda A, Boer JM, Stephens JW, Hofker MH, Tedgui A, Hofman A, Uitterlinden AG, Adamkova V, Pitha J, Onland-Moret NC, Cramer MJ, Nathoe HM, Spiering W, Klungel OH, Kumari M, Whincup PH, Morrow DA, Braund PS, Hall AS, Olsson AG, Doevendans PA, Trip MD, Tobin MD, Hamsten A, Watkins H, Koenig W, Nicolaides AN, Teupser D, Day IN, Carlquist JF, Gaunt TR, Ford I, Sattar N, Tsimikas S, Schwartz GG, Lawlor DA, Morris RW, Sandhu MS, Poledne R, Maitland-van der Zee AH, Khaw KT, Keating BJ, van der Harst P, Price JF, Mehta SR, Yusuf S, Witteman JC, Franco OH, Jukema JW, de Knijff P, Tybjaerg-Hansen A, Rader DJ, Farrall M, Samani NJ, Kivimaki M, Fox KA, Humphries SE, Anderson JL, Boekholdt SM, Palmer TM, Eriksson P, Paré G, Hingorani AD, Sabatine MS, Mallat Z, Casas JP, Talmud PJ. Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol. 2013 Nov 19; 62(21):1966-76. PMID: 23916927; PMCID: PMC3826105.
  698. Krijthe BP, Kunst A, Benjamin EJ, Lip GY, Franco OH, Hofman A, Witteman JC, Stricker BH, Heeringa J. Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060. Eur Heart J. 2013 Sep; 34(35):2746-51. PMID: 23900699; PMCID: PMC3858024.
  699. Ittermann T, Tiller D, Meisinger C, Agger C, Nauck M, Rettig R, Hofman A, Jørgensen T, Linneberg A, Witteman JC, Franco OH, Greiser KH, Werdan K, Döring A, Kluttig A, Stricker BH, Völzke H. High serum thyrotropin levels are associated with current but not with incident hypertension. Thyroid. 2013 Aug; 23(8):955-63. PMID: 23427935; PMCID: PMC3752519.
  700. Driessen LM, Kiefte-de Jong JC, Jaddoe VW, Hofman A, Raat H, de Jongste JC, Moll HA. Physical activity and respiratory symptoms in children: the Generation R Study. Pediatr Pulmonol. 2014 Jan; 49(1):36-42. PMID: 23843308.
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  701. Verlinden VJ, van der Geest JN, Hofman A, Ikram MA. Cognition and gait show a distinct pattern of association in the general population. Alzheimers Dement. 2014 May; 10(3):328-35. PMID: 23849591.
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  702. Korevaar TI, Medici M, de Rijke YB, Visser W, de Muinck Keizer-Schrama SM, Jaddoe VW, Hofman A, Ross HA, Visser WE, Hooijkaas H, Steegers EA, Tiemeier H, Bongers-Schokking JJ, Visser TJ, Peeters RP. Ethnic differences in maternal thyroid parameters during pregnancy: the Generation R study. J Clin Endocrinol Metab. 2013 Sep; 98(9):3678-86. PMID: 23836936.
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  703. van Meurs JB, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, Mälarstig A, Bandinelli S, Bis JC, Blom H, Brown MJ, Chen C, Chen YD, Clarke RJ, Dehghan A, Erdmann J, Ferrucci L, Hamsten A, Hofman A, Hunter DJ, Goel A, Johnson AD, Kathiresan S, Kampman E, Kiel DP, Kiemeney LA, Chambers JC, Kraft P, Lindemans J, McKnight B, Nelson CP, O'Donnell CJ, Psaty BM, Ridker PM, Rivadeneira F, Rose LM, Seedorf U, Siscovick DS, Schunkert H, Selhub J, Ueland PM, Vollenweider P, Waeber G, Waterworth DM, Watkins H, Witteman JC, den Heijer M, Jacques P, Uitterlinden AG, Kooner JS, Rader DJ, Reilly MP, Mooser V, Chasman DI, Samani NJ, Ahmadi KR. Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. Am J Clin Nutr. 2013 Sep; 98(3):668-76. PMID: 23824729; PMCID: PMC4321227.
  704. van Velsen EF, Vernooij MW, Vrooman HA, van der Lugt A, Breteler MM, Hofman A, Niessen WJ, Ikram MA. Brain cortical thickness in the general elderly population: the Rotterdam Scan Study. Neurosci Lett. 2013 Aug 29; 550:189-94. PMID: 23831346.
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  705. van Blijderveen JC, Verhamme KM, Zietse R, Visser LE, Romio SA, Buhre PN, Sturkenboom MC, Hofman A, Straus SM, Stricker BH. Overanticoagulation is associated with renal function decline. J Nephrol. 2013 Jul-Aug; 26(4):691-8. PMID: 23843045.
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  707. Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, de Vries B, Terwindt G, Medland SE, Todt U, McArdle WL, Quaye L, Koiranen M, Ikram MA, Lehtimäki T, Stam AH, Ligthart L, Wedenoja J, Dunham I, Neale BM, Palta P, Hamalainen E, Schürks M, Rose LM, Buring JE, Ridker PM, Steinberg S, Stefansson H, Jakobsson F, Lawlor DA, Evans DM, Ring SM, Färkkilä M, Artto V, Kaunisto MA, Freilinger T, Schoenen J, Frants RR, Pelzer N, Weller CM, Zielman R, Heath AC, Madden PAF, Montgomery GW, Martin NG, Borck G, Göbel H, Heinze A, Heinze-Kuhn K, Williams FMK, Hartikainen AL, Pouta A, van den Ende J, Uitterlinden AG, Hofman A, Amin N, Hottenga JJ, Vink JM, Heikkilä K, Alexander M, Muller-Myhsok B, Schreiber S, Meitinger T, Wichmann HE, Aromaa A, Eriksson JG, Traynor B, Trabzuni D, Rossin E, Lage K, Jacobs SBR, Gibbs JR, Birney E, Kaprio J, Penninx BW, Boomsma DI, van Duijn C, Raitakari O, Jarvelin MR, Zwart JA, Cherkas L, Strachan DP, Kubisch C, Ferrari MD, van den Maagdenberg AMJM, Dichgans M, Wessman M, Smith GD, Stefansson K, Daly MJ, Nyholt DR, Chasman D, Palotie A. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nat Genet. 2013 Aug; 45(8):912-917. PMID: 23793025; PMCID: PMC4041123.
  708. Basten MM, Althoff RR, Tiemeier H, Jaddoe VW, Hofman A, Hudziak JJ, Verhulst FC, van der Ende J. The dysregulation profile in young children: empirically defined classes in the Generation R study. J Am Acad Child Adolesc Psychiatry. 2013 Aug; 52(8):841-850.e2. PMID: 23880494; PMCID: PMC3813902.
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  710. Guxens M, Sonnenschein-van der Voort AM, Tiemeier H, Hofman A, Sunyer J, de Jongste JC, Jaddoe VW, Duijts L. Parental psychological distress during pregnancy and wheezing in preschool children: the Generation R Study. J Allergy Clin Immunol. 2014 Jan; 133(1):59-67.e1-12. PMID: 23777854.
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  711. Isaacs A, Willems SM, Bos D, Dehghan A, Hofman A, Ikram MA, Uitterlinden AG, Oostra BA, Franco OH, Witteman JC, van Duijn CM. Risk scores of common genetic variants for lipid levels influence atherosclerosis and incident coronary heart disease. Arterioscler Thromb Vasc Biol. 2013 Sep; 33(9):2233-9. PMID: 23766260.
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  712. van der Loos MJ, Haring R, Rietveld CA, Baumeister SE, Groenen PJ, Hofman A, de Jong FH, Koellinger PD, Kohlmann T, Nauck MA, Rivadeneira F, Uitterlinden AG, van Rooij FJ, Wallaschofski H, Thurik AR. Serum testosterone levels in males are not associated with entrepreneurial behavior in two independent observational studies. Physiol Behav. 2013 Jul 02; 119:110-4. PMID: 23770427.
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  713. Sim X, Jensen RA, Ikram MK, Cotch MF, Li X, MacGregor S, Xie J, Smith AV, Boerwinkle E, Mitchell P, Klein R, Klein BE, Glazer NL, Lumley T, McKnight B, Psaty BM, de Jong PT, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, Aspelund T, Eiriksdottir G, Harris TB, Jonasson F, Launer LJ, Attia J, Baird PN, Harrap S, Holliday EG, Inouye M, Rochtchina E, Scott RJ, Viswanathan A, Li G, Smith NL, Wiggins KL, Kuo JZ, Taylor KD, Hewitt AW, Martin NG, Montgomery GW, Sun C, Young TL, Mackey DA, van Zuydam NR, Doney AS, Palmer CN, Morris AD, Rotter JI, Tai ES, Gudnason V, Vingerling JR, Siscovick DS, Wang JJ, Wong TY. Genetic loci for retinal arteriolar microcirculation. PLoS One. 2013; 8(6):e65804. PMID: 23776548; PMCID: PMC3680438.
  714. Makurthou AA, Oei L, Saddy SE, Breda SJ, Castaño-Betancourt MC, Hofman A, van Meurs JB, Uitterlinden AG, Rivadeneira F, Oei EH. Scheuermann's Disease: Evaluation of Radiological Criteria and Population Prevalence. Spine (Phila Pa 1976). 2013 Jun 11. PMID: 23759818.
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  715. Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, Ferreira T, Gustafsson S, Locke AE, Mathieson I, Scherag A, Vedantam S, Wood AR, Liang L, Steinthorsdottir V, Thorleifsson G, Dermitzakis ET, Dimas AS, Karpe F, Min JL, Nicholson G, Clegg DJ, Person T, Krohn JP, Bauer S, Buechler C, Eisinger K, Bonnefond A, Froguel P, Hottenga JJ, Prokopenko I, Waite LL, Harris TB, Smith AV, Shuldiner AR, McArdle WL, Caulfield MJ, Munroe PB, Grönberg H, Chen YD, Li G, Beckmann JS, Johnson T, Thorsteinsdottir U, Teder-Laving M, Khaw KT, Wareham NJ, Zhao JH, Amin N, Oostra BA, Kraja AT, Province MA, Cupples LA, Heard-Costa NL, Kaprio J, Ripatti S, Surakka I, Collins FS, Saramies J, Tuomilehto J, Jula A, Salomaa V, Erdmann J, Hengstenberg C, Loley C, Schunkert H, Lamina C, Wichmann HE, Albrecht E, Gieger C, Hicks AA, Johansson A, Pramstaller PP, Kathiresan S, Speliotes EK, Penninx B, Hartikainen AL, Jarvelin MR, Gyllensten U, Boomsma DI, Campbell H, Wilson JF, Chanock SJ, Farrall M, Goel A, Medina-Gomez C, Rivadeneira F, Estrada K, Uitterlinden AG, Hofman A, Zillikens MC, den Heijer M, Kiemeney LA, Maschio A, Hall P, Tyrer J, Teumer A, Völzke H, Kovacs P, Tönjes A, Mangino M, Spector TD, Hayward C, Rudan I, Hall AS, Samani NJ, Attwood AP, Sambrook JG, Hung J, Palmer LJ, Lokki ML, Sinisalo J, Boucher G, Huikuri H, Lorentzon M, Ohlsson C, Eklund N, Eriksson JG, Barlassina C, Rivolta C, Nolte IM, Snieder H, Van der Klauw MM, Van Vliet-Ostaptchouk JV, Gejman PV, Shi J, Jacobs KB, Wang Z, Bakker SJ, Mateo Leach I, Navis G, van der Harst P, Martin NG, Medland SE, Montgomery GW, Yang J, Chasman DI, Ridker PM, Rose LM, Lehtimäki T, Raitakari O, Absher D, Iribarren C, Basart H, Hovingh KG, Hyppönen E, Power C, Anderson D, Beilby JP, Hui J, Jolley J, Sager H, Bornstein SR, Schwarz PE, Kristiansson K, Perola M, Lindström J, Swift AJ, Uusitupa M, Atalay M, Lakka TA, Rauramaa R, Bolton JL, Fowkes G, Fraser RM, Price JF, Fischer K, Krjutå Kov K, Metspalu A, Mihailov E, Langenberg C, Luan J, Ong KK, Chines PS, Keinanen-Kiukaanniemi SM, Saaristo TE, Edkins S, Franks PW, Hallmans G, Shungin D, Morris AD, Palmer CN, Erbel R, Moebus S, Nöthen MM, Pechlivanis S, Hveem K, Narisu N, Hamsten A, Humphries SE, Strawbridge RJ, Tremoli E, Grallert H, Thorand B, Illig T, Koenig W, Müller-Nurasyid M, Peters A, Boehm BO, Kleber ME, März W, Winkelmann BR, Kuusisto J, Laakso M, Arveiler D, Cesana G, Kuulasmaa K, Virtamo J, Yarnell JW, Kuh D, Wong A, Lind L, de Faire U, Gigante B, Magnusson PK, Pedersen NL, Dedoussis G, Dimitriou M, Kolovou G, Kanoni S, Stirrups K, Bonnycastle LL, Njølstad I, Wilsgaard T, Ganna A, Rehnberg E, Hingorani A, Kivimaki M, Kumari M, Assimes TL, Barroso I, Boehnke M, Borecki IB, Deloukas P, Fox CS, Frayling T, Groop LC, Haritunians T, Hunter D, Ingelsson E, Kaplan R, Mohlke KL, O'Connell JR, Schlessinger D, Strachan DP, Stefansson K, van Duijn CM, Abecasis GR, McCarthy MI, Hirschhorn JN, Qi L, Loos RJ, Lindgren CM, North KE, Heid IM. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet. 2013 Jun; 9(6):e1003500. PMID: 23754948; PMCID: PMC3674993.
  716. van Batenburg-Eddes T, Henrichs J, Schenk JJ, Sincer I, de Groot L, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Early infant neuromotor assessment is associated with language and nonverbal cognitive function in toddlers: the Generation R Study. J Dev Behav Pediatr. 2013 Jun; 34(5):326-34. PMID: 23708382.
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  717. Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, Benke KS, Bielak LF, Boatman JA, Boyle PA, Davies G, de Leeuw C, Eklund N, Evans DS, Ferhmann R, Fischer K, Gieger C, Gjessing HK, Hägg S, Harris JR, Hayward C, Holzapfel C, Ibrahim-Verbaas CA, Ingelsson E, Jacobsson B, Joshi PK, Jugessur A, Kaakinen M, Kanoni S, Karjalainen J, Kolcic I, Kristiansson K, Kutalik Z, Lahti J, Lee SH, Lin P, Lind PA, Liu Y, Lohman K, Loitfelder M, McMahon G, Vidal PM, Meirelles O, Milani L, Myhre R, Nuotio ML, Oldmeadow CJ, Petrovic KE, Peyrot WJ, Polasek O, Quaye L, Reinmaa E, Rice JP, Rizzi TS, Schmidt H, Schmidt R, Smith AV, Smith JA, Tanaka T, Terracciano A, van der Loos MJ, Vitart V, Völzke H, Wellmann J, Yu L, Zhao W, Allik J, Attia JR, Bandinelli S, Bastardot F, Beauchamp J, Bennett DA, Berger K, Bierut LJ, Boomsma DI, Bültmann U, Campbell H, Chabris CF, Cherkas L, Chung MK, Cucca F, de Andrade M, De Jager PL, De Neve JE, Deary IJ, Dedoussis GV, Deloukas P, Dimitriou M, Eiríksdóttir G, Elderson MF, Eriksson JG, Evans DM, Faul JD, Ferrucci L, Garcia ME, Grönberg H, Guðnason V, Hall P, Harris JM, Harris TB, Hastie ND, Heath AC, Hernandez DG, Hoffmann W, Hofman A, Holle R, Holliday EG, Hottenga JJ, Iacono WG, Illig T, Järvelin MR, Kähönen M, Kaprio J, Kirkpatrick RM, Kowgier M, Latvala A, Launer LJ, Lawlor DA, Lehtimäki T, Li J, Lichtenstein P, Lichtner P, Liewald DC, Madden PA, Magnusson PK, Mäkinen TE, Masala M, McGue M, Metspalu A, Mielck A, Miller MB, Montgomery GW, Mukherjee S, Nyholt DR, Oostra BA, Palmer LJ, Palotie A, Penninx BW, Perola M, Peyser PA, Preisig M, Räikkönen K, Raitakari OT, Realo A, Ring SM, Ripatti S, Rivadeneira F, Rudan I, Rustichini A, Salomaa V, Sarin AP, Schlessinger D, Scott RJ, Snieder H, St Pourcain B, Starr JM, Sul JH, Surakka I, Svento R, Teumer A, Tiemeier H, van Rooij FJ, Van Wagoner DR, Vartiainen E, Viikari J, Vollenweider P, Vonk JM, Waeber G, Weir DR, Wichmann HE, Widen E, Willemsen G, Wilson JF, Wright AF, Conley D, Davey-Smith G, Franke L, Groenen PJ, Hofman A, Johannesson M, Kardia SL, Krueger RF, Laibson D, Martin NG, Meyer MN, Posthuma D, Thurik AR, Timpson NJ, Uitterlinden AG, van Duijn CM, Visscher PM, Benjamin DJ, Cesarini D, Koellinger PD. GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science. 2013 Jun 21; 340(6139):1467-71. PMID: 23722424; PMCID: PMC3751588.
  718. Heppe DH, Medina-Gomez C, Hofman A, Franco OH, Rivadeneira F, Jaddoe VW. Maternal first-trimester diet and childhood bone mass: the Generation R Study. Am J Clin Nutr. 2013 Jul; 98(1):224-32. PMID: 23719545.
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  719. Boomsma DI, Wijmenga C, Slagboom EP, Swertz MA, Karssen LC, Abdellaoui A, Ye K, Guryev V, Vermaat M, van Dijk F, Francioli LC, Hottenga JJ, Laros JF, Li Q, Li Y, Cao H, Chen R, Du Y, Li N, Cao S, van Setten J, Menelaou A, Pulit SL, Hehir-Kwa JY, Beekman M, Elbers CC, Byelas H, de Craen AJ, Deelen P, Dijkstra M, den Dunnen JT, de Knijff P, Houwing-Duistermaat J, Koval V, Estrada K, Hofman A, Kanterakis A, Enckevort Dv, Mai H, Kattenberg M, van Leeuwen EM, Neerincx PB, Oostra B, Rivadeneira F, Suchiman EH, Uitterlinden AG, Willemsen G, Wolffenbuttel BH, Wang J, de Bakker PI, van Ommen GJ, van Duijn CM. The Genome of the Netherlands: design, and project goals. Eur J Hum Genet. 2014 Feb; 22(2):221-7. PMID: 23714750; PMCID: PMC3895638.
  720. Taal HR, Vd Heijden AJ, Steegers EA, Hofman A, Jaddoe VW. Small and large size for gestational age at birth, infant growth, and childhood overweight. Obesity (Silver Spring). 2013 Jun; 21(6):1261-8. PMID: 23666877.
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  721. van 't Hof FN, Ruigrok YM, Baas AF, Kiemeney LA, Vermeulen SH, Uitterlinden AG, Hofman A, Rivadeneira F, Rinkel GJ, de Bakker PI. Impact of inherited genetic variants associated with lipid profile, hypertension, and coronary artery disease on the risk of intracranial and abdominal aortic aneurysms. Circ Cardiovasc Genet. 2013 Jun; 6(3):264-70. PMID: 23661678.
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  722. Mayerle J, den Hoed CM, Schurmann C, Stolk L, Homuth G, Peters MJ, Capelle LG, Zimmermann K, Rivadeneira F, Gruska S, Völzke H, de Vries AC, Völker U, Teumer A, van Meurs JB, Steinmetz I, Nauck M, Ernst F, Weiss FU, Hofman A, Zenker M, Kroemer HK, Prokisch H, Uitterlinden AG, Lerch MM, Kuipers EJ, Kuipers E. Identification of genetic loci associated with Helicobacter pylori serologic status. JAMA. 2013 May 08; 309(18):1912-20. PMID: 23652523.
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  723. Tang W, Teichert M, Chasman DI, Heit JA, Morange PE, Li G, Pankratz N, Leebeek FW, Paré G, de Andrade M, Tzourio C, Psaty BM, Basu S, Ruiter R, Rose L, Armasu SM, Lumley T, Heckbert SR, Uitterlinden AG, Lathrop M, Rice KM, Cushman M, Hofman A, Lambert JC, Glazer NL, Pankow JS, Witteman JC, Amouyel P, Bis JC, Bovill EG, Kong X, Tracy RP, Boerwinkle E, Rotter JI, Trégouët DA, Loth DW, Stricker BHC, Ridker PM, Folsom AR, Smith NL. A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Genet Epidemiol. 2013 Jul; 37(5):512-521. PMID: 23650146; PMCID: PMC3990406.
  724. Gaillard R, Durmus B, Hofman A, Mackenbach JP, Steegers EA, Jaddoe VW. Risk factors and outcomes of maternal obesity and excessive weight gain during pregnancy. Obesity (Silver Spring). 2013 May; 21(5):1046-55. PMID: 23784909.
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  725. Tanaka T, Ngwa JS, van Rooij FJ, Zillikens MC, Wojczynski MK, Frazier-Wood AC, Houston DK, Kanoni S, Lemaitre RN, Luan J, Mikkilä V, Renstrom F, Sonestedt E, Zhao JH, Chu AY, Qi L, Chasman DI, de Oliveira Otto MC, Dhurandhar EJ, Feitosa MF, Johansson I, Khaw KT, Lohman KK, Manichaikul A, McKeown NM, Mozaffarian D, Singleton A, Stirrups K, Viikari J, Ye Z, Bandinelli S, Barroso I, Deloukas P, Forouhi NG, Hofman A, Liu Y, Lyytikäinen LP, North KE, Dimitriou M, Hallmans G, Kähönen M, Langenberg C, Ordovas JM, Uitterlinden AG, Hu FB, Kalafati IP, Raitakari O, Franco OH, Johnson A, Emilsson V, Schrack JA, Semba RD, Siscovick DS, Arnett DK, Borecki IB, Franks PW, Kritchevsky SB, Lehtimäki T, Loos RJ, Orho-Melander M, Rotter JI, Wareham NJ, Witteman JC, Ferrucci L, Dedoussis G, Cupples LA, Nettleton JA. Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake. Am J Clin Nutr. 2013 Jun; 97(6):1395-402. PMID: 23636237; PMCID: PMC3652928.
  726. Schiphof D, Kerkhof HJ, Damen J, de Klerk BM, Hofman A, Koes BW, van Meurs JB, Bierma-Zeinstra SM. Factors for pain in patients with different grades of knee osteoarthritis. Arthritis Care Res (Hoboken). 2013 May; 65(5):695-702. PMID: 23203619.
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  727. Nanchen D, Leening MJ, Locatelli I, Cornuz J, Kors JA, Heeringa J, Deckers JW, Hofman A, Franco OH, Stricker BH, Witteman JC, Dehghan A. Resting heart rate and the risk of heart failure in healthy adults: the Rotterdam Study. Circ Heart Fail. 2013 May; 6(3):403-10. PMID: 23599310.
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  728. Rodenburg EM, Hoorn EJ, Ruiter R, Lous JJ, Hofman A, Uitterlinden AG, Stricker BH, Visser LE. Thiazide-associated hyponatremia: a population-based study. Am J Kidney Dis. 2013 Jul; 62(1):67-72. PMID: 23602191.
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  735. Loth DW, Ittermann T, Lahousse L, Hofman A, Leufkens HG, Brusselle GG, Stricker BH. Normal spirometry values in healthy elderly: the Rotterdam Study. Eur J Epidemiol. 2013 Apr; 28(4):329-34. PMID: 23539359.
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  736. van den Hil LC, Rob Taal H, de Jonge LL, Heppe DH, Steegers EA, Hofman A, van der Heijden AJ, Jaddoe VW. Maternal first-trimester dietary intake and childhood blood pressure: the Generation R Study. Br J Nutr. 2013 Oct; 110(8):1454-64. PMID: 23528150.
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  737. Verhaaren BF, Vernooij MW, de Boer R, Hofman A, Niessen WJ, van der Lugt A, Ikram MA. High blood pressure and cerebral white matter lesion progression in the general population. Hypertension. 2013 Jun; 61(6):1354-9. PMID: 23529163.
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  738. Wijtzes AI, Kooijman MN, Kiefte-de Jong JC, de Vries SI, Henrichs J, Jansen W, Jaddoe VW, Hofman A, Moll HA, Raat H. Correlates of physical activity in 2-year-old toddlers: the generation R study. J Pediatr. 2013 Sep; 163(3):791-9.e1-2. PMID: 23523279.
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  739. Verhaaren BF, Vernooij MW, Dehghan A, Vrooman HA, de Boer R, Hofman A, Witteman JC, Niessen WJ, Breteler MM, van der Lugt A, Ikram MA. The relation of uric acid to brain atrophy and cognition: the Rotterdam Scan Study. Neuroepidemiology. 2013; 41(1):29-34. PMID: 23548762.
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  740. Flohil SC, van der Leest RJ, Dowlatshahi EA, Hofman A, de Vries E, Nijsten T. Prevalence of actinic keratosis and its risk factors in the general population: the Rotterdam Study. J Invest Dermatol. 2013 Aug; 133(8):1971-8. PMID: 23510990.
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  741. Alonso A, Krijthe BP, Aspelund T, Stepas KA, Pencina MJ, Moser CB, Sinner MF, Sotoodehnia N, Fontes JD, Janssens AC, Kronmal RA, Magnani JW, Witteman JC, Chamberlain AM, Lubitz SA, Schnabel RB, Agarwal SK, McManus DD, Ellinor PT, Larson MG, Burke GL, Launer LJ, Hofman A, Levy D, Gottdiener JS, Kääb S, Couper D, Harris TB, Soliman EZ, Stricker BH, Gudnason V, Heckbert SR, Benjamin EJ. Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium. J Am Heart Assoc. 2013 Mar 18; 2(2):e000102. PMID: 23537808; PMCID: PMC3647274.
  742. Dowlatshahi EA, Kavousi M, Nijsten T, Ikram MA, Hofman A, Franco OH, Wakkee M. Psoriasis is not associated with atherosclerosis and incident cardiovascular events: the Rotterdam Study. J Invest Dermatol. 2013 Oct; 133(10):2347-2354. PMID: 23492918.
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  743. Steenweg-de Graaff J, Tiemeier H, Steegers-Theunissen RP, Hofman A, Jaddoe VW, Verhulst FC, Roza SJ. Maternal dietary patterns during pregnancy and child internalising and externalising problems. The Generation R Study. Clin Nutr. 2014 Feb; 33(1):115-21. PMID: 23541912.
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  744. Visser AM, Jaddoe VW, Hofman A, Moll HA, Arts WF. Validity of parentally reported febrile seizures: the generation R study. Neuropediatrics. 2013 Aug; 44(4):183-6. PMID: 23483446.
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  745. Gaillard R, Arends LR, Steegers EA, Hofman A, Jaddoe VW. Second- and third-trimester placental hemodynamics and the risks of pregnancy complications: the Generation R Study. Am J Epidemiol. 2013 Apr 15; 177(8):743-54. PMID: 23479346.
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  746. Leermakers ET, Sonnenschein-van der Voort AM, Gaillard R, Hofman A, de Jongste JC, Jaddoe VW, Duijts L. Maternal weight, gestational weight gain and preschool wheezing: the Generation R Study. Eur Respir J. 2013 Nov; 42(5):1234-43. PMID: 23471348.
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  747. Stambolian D, Wojciechowski R, Oexle K, Pirastu M, Li X, Raffel LJ, Cotch MF, Chew EY, Klein B, Klein R, Wong TY, Simpson CL, Klaver CC, van Duijn CM, Verhoeven VJ, Baird PN, Vitart V, Paterson AD, Mitchell P, Saw SM, Fossarello M, Kazmierkiewicz K, Murgia F, Portas L, Schache M, Richardson A, Xie J, Wang JJ, Rochtchina E, Viswanathan AC, Hayward C, Wright AF, Polasek O, Campbell H, Rudan I, Oostra BA, Uitterlinden AG, Hofman A, Rivadeneira F, Amin N, Karssen LC, Vingerling JR, Hosseini SM, Döring A, Bettecken T, Vatavuk Z, Gieger C, Wichmann HE, Wilson JF, Fleck B, Foster PJ, Topouzis F, McGuffin P, Sim X, Inouye M, Holliday EG, Attia J, Scott RJ, Rotter JI, Meitinger T, Bailey-Wilson JE. Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error. Hum Mol Genet. 2013 Jul 01; 22(13):2754-64. PMID: 23474815; PMCID: PMC3674806.
  748. Castaño-Betancourt MC, Rivadeneira F, Bierma-Zeinstra S, Kerkhof HJ, Hofman A, Uitterlinden AG, van Meurs JB. Bone parameters across different types of hip osteoarthritis and their relationship to osteoporotic fracture risk. Arthritis Rheum. 2013 Mar; 65(3):693-700. PMID: 23203458.
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  749. Cousminer DL, Berry DJ, Timpson NJ, Ang W, Thiering E, Byrne EM, Taal HR, Huikari V, Bradfield JP, Kerkhof M, Groen-Blokhuis MM, Kreiner-Møller E, Marinelli M, Holst C, Leinonen JT, Perry JR, Surakka I, Pietiläinen O, Kettunen J, Anttila V, Kaakinen M, Sovio U, Pouta A, Das S, Lagou V, Power C, Prokopenko I, Evans DM, Kemp JP, St Pourcain B, Ring S, Palotie A, Kajantie E, Osmond C, Lehtimäki T, Viikari JS, Kähönen M, Warrington NM, Lye SJ, Palmer LJ, Tiesler CM, Flexeder C, Montgomery GW, Medland SE, Hofman A, Hakonarson H, Guxens M, Bartels M, Salomaa V, Murabito JM, Kaprio J, Sørensen TI, Ballester F, Bisgaard H, Boomsma DI, Koppelman GH, Grant SF, Jaddoe VW, Martin NG, Heinrich J, Pennell CE, Raitakari OT, Eriksson JG, Smith GD, Hyppönen E, Järvelin MR, McCarthy MI, Ripatti S, Widén E. Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Hum Mol Genet. 2013 Jul 01; 22(13):2735-47. PMID: 23449627; PMCID: PMC3674797.
  750. Guxens M, Tiemeier H, Jansen PW, Raat H, Hofman A, Sunyer J, Jaddoe VW. Parental psychological distress during pregnancy and early growth in preschool children: the generation R study. Am J Epidemiol. 2013 Mar 15; 177(6):538-47. PMID: 23436897.
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  751. de Groot M, Verhaaren BF, de Boer R, Klein S, Hofman A, van der Lugt A, Ikram MA, Niessen WJ, Vernooij MW. Changes in normal-appearing white matter precede development of white matter lesions. Stroke. 2013 Apr; 44(4):1037-42. PMID: 23429507.
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  752. Devore EE, Feskens E, Ikram MA, den Heijer T, Vernooij M, van der Lijn F, Hofman A, Niessen WJ, Breteler MM. Total antioxidant capacity of the diet and major neurologic outcomes in older adults. Neurology. 2013 Mar 05; 80(10):904-10. PMID: 23427318; PMCID: PMC3653208.
  753. Ma H, Lin H, Hofman A, Hu Y, Li X, He W, Jeekel J, Jin X, Gao J, Zhao N, Gao X. Low-grade albuminuria is associated with carotid atherosclerosis in normotensive and euglycemic Chinese middle-aged and elderly adults: the Shanghai Changfeng Study. Atherosclerosis. 2013 May; 228(1):237-42. PMID: 23453351.
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  754. Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Höhn R, MacGregor S, Hewitt AW, Nag A, Cheng CY, Yonova-Doing E, Zhou X, Ikram MK, Buitendijk GH, McMahon G, Kemp JP, Pourcain BS, Simpson CL, Mäkelä KM, Lehtimäki T, Kähönen M, Paterson AD, Hosseini SM, Wong HS, Xu L, Jonas JB, Pärssinen O, Wedenoja J, Yip SP, Ho DW, Pang CP, Chen LJ, Burdon KP, Craig JE, Klein BE, Klein R, Haller T, Metspalu A, Khor CC, Tai ES, Aung T, Vithana E, Tay WT, Barathi VA, Chen P, Li R, Liao J, Zheng Y, Ong RT, Döring A, Evans DM, Timpson NJ, Verkerk AJ, Meitinger T, Raitakari O, Hawthorne F, Spector TD, Karssen LC, Pirastu M, Murgia F, Ang W, Mishra A, Montgomery GW, Pennell CE, Cumberland PM, Cotlarciuc I, Mitchell P, Wang JJ, Schache M, Janmahasatian S, Janmahasathian S, Igo RP, Lass JH, Chew E, Iyengar SK, Gorgels TG, Rudan I, Hayward C, Wright AF, Polasek O, Vatavuk Z, Wilson JF, Fleck B, Zeller T, Mirshahi A, Müller C, Uitterlinden AG, Rivadeneira F, Vingerling JR, Hofman A, Oostra BA, Amin N, Bergen AA, Teo YY, Rahi JS, Vitart V, Williams C, Baird PN, Wong TY, Oexle K, Pfeiffer N, Mackey DA, Young TL, van Duijn CM, Saw SM, Bailey-Wilson JE, Stambolian D, Klaver CC, Hammond CJ. Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet. 2013 Mar; 45(3):314-8. PMID: 23396134; PMCID: PMC3740568.
  755. Saridjan NS, Henrichs J, Schenk JJ, Jaddoe VW, Hofman A, Kirschbaum C, Verhulst FC, Tiemeier H. Diurnal cortisol rhythm and cognitive functioning in toddlers: the Generation R Study. Child Neuropsychol. 2014 Mar; 20(2):210-29. PMID: 23391483.
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  756. Porcu E, Medici M, Pistis G, Volpato CB, Wilson SG, Cappola AR, Bos SD, Deelen J, den Heijer M, Freathy RM, Lahti J, Liu C, Lopez LM, Nolte IM, O'Connell JR, Tanaka T, Trompet S, Arnold A, Bandinelli S, Beekman M, Böhringer S, Brown SJ, Buckley BM, Camaschella C, de Craen AJ, Davies G, de Visser MC, Ford I, Forsen T, Frayling TM, Fugazzola L, Gögele M, Hattersley AT, Hermus AR, Hofman A, Houwing-Duistermaat JJ, Jensen RA, Kajantie E, Kloppenburg M, Lim EM, Masciullo C, Mariotti S, Minelli C, Mitchell BD, Nagaraja R, Netea-Maier RT, Palotie A, Persani L, Piras MG, Psaty BM, Räikkönen K, Richards JB, Rivadeneira F, Sala C, Sabra MM, Sattar N, Shields BM, Soranzo N, Starr JM, Stott DJ, Sweep FC, Usala G, van der Klauw MM, van Heemst D, van Mullem A, Vermeulen SH, Visser WE, Walsh JP, Westendorp RG, Widen E, Zhai G, Cucca F, Deary IJ, Eriksson JG, Ferrucci L, Fox CS, Jukema JW, Kiemeney LA, Pramstaller PP, Schlessinger D, Shuldiner AR, Slagboom EP, Uitterlinden AG, Vaidya B, Visser TJ, Wolffenbuttel BH, Meulenbelt I, Rotter JI, Spector TD, Hicks AA, Toniolo D, Sanna S, Peeters RP, Naitza S. A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. PLoS Genet. 2013; 9(2):e1003266. PMID: 23408906; PMCID: PMC3567175.
  757. de Bruijn RF, Schrijvers EM, de Groot KA, Witteman JC, Hofman A, Franco OH, Koudstaal PJ, Ikram MA. The association between physical activity and dementia in an elderly population: the Rotterdam Study. Eur J Epidemiol. 2013 Mar; 28(3):277-83. PMID: 23385659.
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  758. Taal HR, de Jonge LL, Tiemeier H, van Osch-Gevers L, Hofman A, Verhulst FC, Helbing WA, van der Heijden AJ, Jaddoe VW. Parental psychological distress during pregnancy and childhood cardiovascular development. The Generation R Study. Early Hum Dev. 2013 Aug; 89(8):547-53. PMID: 23391482.
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  759. Jensen RA, Sim X, Li X, Cotch MF, Ikram MK, Holliday EG, Eiriksdottir G, Harris TB, Jonasson F, Klein BE, Launer LJ, Smith AV, Boerwinkle E, Cheung N, Hewitt AW, Liew G, Mitchell P, Wang JJ, Attia J, Scott R, Glazer NL, Lumley T, McKnight B, Psaty BM, Taylor K, Hofman A, de Jong PT, Rivadeneira F, Uitterlinden AG, Tay WT, Teo YY, Seielstad M, Liu J, Cheng CY, Saw SM, Aung T, Ganesh SK, O'Donnell CJ, Nalls MA, Wiggins KL, Kuo JZ, van Duijn CM, Gudnason V, Klein R, Siscovick DS, Rotter JI, Tai ES, Vingerling J, Wong TY. Genome-wide association study of retinopathy in individuals without diabetes. PLoS One. 2013; 8(2):e54232. PMID: 23393555; PMCID: PMC3564946.
  760. Wijtzes AI, Jansen W, Jaddoe VW, Moll HA, Tiemeier H, Verhulst FC, Hofman A, Mackenbach JP, Raat H. Ethnic background and television viewing time among 4-year-old preschool children: the generation R study. J Dev Behav Pediatr. 2013 Feb; 34(2):63-71. PMID: 23369955.
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  761. White T, El Marroun H, Nijs I, Schmidt M, van der Lugt A, Wielopolki PA, Jaddoe VW, Hofman A, Krestin GP, Tiemeier H, Verhulst FC. Pediatric population-based neuroimaging and the Generation R Study: the intersection of developmental neuroscience and epidemiology. Eur J Epidemiol. 2013 Jan; 28(1):99-111. PMID: 23354984.
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  762. Ganna A, Rivadeneira F, Hofman A, Uitterlinden AG, Magnusson PK, Pedersen NL, Ingelsson E, Tiemeier H. Genetic determinants of mortality. Can findings from genome-wide association studies explain variation in human mortality? Hum Genet. 2013 May; 132(5):553-61. PMID: 23354976.
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  763. Hruby A, Ngwa JS, Renström F, Wojczynski MK, Ganna A, Hallmans G, Houston DK, Jacques PF, Kanoni S, Lehtimäki T, Lemaitre RN, Manichaikul A, North KE, Ntalla I, Sonestedt E, Tanaka T, van Rooij FJ, Bandinelli S, Djoussé L, Grigoriou E, Johansson I, Lohman KK, Pankow JS, Raitakari OT, Riserus U, Yannakoulia M, Zillikens MC, Hassanali N, Liu Y, Mozaffarian D, Papoutsakis C, Syvänen AC, Uitterlinden AG, Viikari J, Groves CJ, Hofman A, Lind L, McCarthy MI, Mikkilä V, Mukamal K, Franco OH, Borecki IB, Cupples LA, Dedoussis GV, Ferrucci L, Hu FB, Ingelsson E, Kähönen M, Kao WH, Kritchevsky SB, Orho-Melander M, Prokopenko I, Rotter JI, Siscovick DS, Witteman JC, Franks PW, Meigs JB, McKeown NM, Nettleton JA. Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies. J Nutr. 2013 Mar; 143(3):345-53. PMID: 23343670; PMCID: PMC3713023.
  764. Koehler EM, Schouten JN, Hansen BE, Hofman A, Stricker BH, Janssen HL. External validation of the fatty liver index for identifying nonalcoholic fatty liver disease in a population-based study. Clin Gastroenterol Hepatol. 2013 Sep; 11(9):1201-4. PMID: 23353640.
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  765. Liamis G, Rodenburg EM, Hofman A, Zietse R, Stricker BH, Hoorn EJ. Electrolyte disorders in community subjects: prevalence and risk factors. Am J Med. 2013 Mar; 126(3):256-63. PMID: 23332973.
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  766. Krijthe BP, Leening MJ, Heeringa J, Kors JA, Hofman A, Franco OH, Witteman JC, Stricker BH. Unrecognized myocardial infarction and risk of atrial fibrillation: the Rotterdam Study. Int J Cardiol. 2013 Sep 30; 168(2):1453-7. PMID: 23332895.
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  767. Oei L, Zillikens MC, Dehghan A, Buitendijk GH, Castaño-Betancourt MC, Estrada K, Stolk L, Oei EH, van Meurs JB, Janssen JA, Hofman A, van Leeuwen JP, Witteman JC, Pols HA, Uitterlinden AG, Klaver CC, Franco OH, Rivadeneira F. High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study. Diabetes Care. 2013 Jun; 36(6):1619-28. PMID: 23315602; PMCID: PMC3661786.
  768. Direk N, Schrijvers EM, de Bruijn RF, Mirza S, Hofman A, Ikram MA, Tiemeier H. Plasma amyloid ß, depression, and dementia in community-dwelling elderly. J Psychiatr Res. 2013 Apr; 47(4):479-85. PMID: 23312759.
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  769. Perry JR, Corre T, Esko T, Chasman DI, Fischer K, Franceschini N, He C, Kutalik Z, Mangino M, Rose LM, Vernon Smith A, Stolk L, Sulem P, Weedon MN, Zhuang WV, Arnold A, Ashworth A, Bergmann S, Buring JE, Burri A, Chen C, Cornelis MC, Couper DJ, Goodarzi MO, Gudnason V, Harris T, Hofman A, Jones M, Kraft P, Launer L, Laven JS, Li G, McKnight B, Masciullo C, Milani L, Orr N, Psaty BM, Ridker PM, Rivadeneira F, Sala C, Salumets A, Schoemaker M, Traglia M, Waeber G, Chanock SJ, Demerath EW, Garcia M, Hankinson SE, Hu FB, Hunter DJ, Lunetta KL, Metspalu A, Montgomery GW, Murabito JM, Newman AB, Ong KK, Spector TD, Stefansson K, Swerdlow AJ, Thorsteinsdottir U, Van Dam RM, Uitterlinden AG, Visser JA, Vollenweider P, Toniolo D, Murray A. A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet. 2013 Apr 01; 22(7):1465-72. PMID: 23307926; PMCID: PMC3596848.
  770. Kiefte-de Jong JC, Jaddoe VW, Uitterlinden AG, Steegers EA, Willemsen SP, Hofman A, Hooijkaas H, Moll HA. Levels of antibodies against tissue transglutaminase during pregnancy are associated with reduced fetal weight and birth weight. Gastroenterology. 2013 Apr; 144(4):726-735.e2. PMID: 23313966.
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  771. Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, de Geus E, De Jager PL, Diez-Roux AV, Purcell S, Hu FB, Rimma EB, Hunter DJ, Jensen MK, Curhan G, Rice K, Penman AD, Rotter JI, Sotoodehnia N, Emeny R, Eriksson JG, Evans DA, Ferrucci L, Fornage M, Gudnason V, Hofman A, Illig T, Kardia S, Kelly-Hayes M, Koenen K, Kraft P, Kuningas M, Massaro JM, Melzer D, Mulas A, Mulder CL, Murray A, Oostra BA, Palotie A, Penninx B, Petersmann A, Pilling LC, Psaty B, Rawal R, Reiman EM, Schulz A, Shulman JM, Singleton AB, Smith AV, Sutin AR, Uitterlinden AG, Völzke H, Widen E, Yaffe K, Zonderman AB, Cucca F, Harris T, Ladwig KH, Llewellyn DJ, Räikkönen K, Tanaka T, van Duijn CM, Grabe HJ, Launer LJ, Lunetta KL, Mosley TH, Newman AB, Tiemeier H, Murabito J. A genome-wide association study of depressive symptoms. Biol Psychiatry. 2013 Apr 01; 73(7):667-78. PMID: 23290196; PMCID: PMC3845085.
  772. Altorf-van der Kuil W, Engberink MF, De Neve M, van Rooij FJ, Hofman A, van't Veer P, Witteman JC, Franco OH, Geleijnse JM. Dietary amino acids and the risk of hypertension in a Dutch older population: the Rotterdam Study. Am J Clin Nutr. 2013 Feb; 97(2):403-10. PMID: 23283504.
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  773. Williams FM, Carter AM, Hysi PG, Surdulescu G, Hodgkiss D, Soranzo N, Traylor M, Bevan S, Dichgans M, Rothwell PM, Sudlow C, Farrall M, Silander K, Kaunisto M, Wagner P, Saarela O, Kuulasmaa K, Virtamo J, Salomaa V, Amouyel P, Arveiler D, Ferrieres J, Wiklund PG, Ikram MA, Hofman A, Boncoraglio GB, Parati EA, Helgadottir A, Gretarsdottir S, Thorsteinsdottir U, Thorleifsson G, Stefansson K, Seshadri S, DeStefano A, Gschwendtner A, Psaty B, Longstreth W, Mitchell BD, Cheng YC, Clarke R, Ferrario M, Bis JC, Levi C, Attia J, Holliday EG, Scott RJ, Fornage M, Sharma P, Furie KL, Rosand J, Nalls M, Meschia J, Mosely TH, Evans A, Palotie A, Markus HS, Grant PJ, Spector TD. Ischemic stroke is associated with the ABO locus: the EuroCLOT study. Ann Neurol. 2013 Jan; 73(1):16-31. PMID: 23381943; PMCID: PMC3582024.
  774. Rijlaarsdam J, Stevens GW, van der Ende J, Hofman A, Jaddoe VW, Mackenbach JP, Verhulst FC, Tiemeier H. Economic disadvantage and young children's emotional and behavioral problems: mechanisms of risk. J Abnorm Child Psychol. 2013 Jan; 41(1):125-37. PMID: 22736330; PMCID: PMC3540352.
  775. Ferket BS, van Kempen BJ, Heeringa J, Spronk S, Fleischmann KE, Nijhuis RL, Hofman A, Steyerberg EW, Hunink MG. Personalized prediction of lifetime benefits with statin therapy for asymptomatic individuals: a modeling study. PLoS Med. 2012; 9(12):e1001361. PMID: 23300388; PMCID: PMC3531501.
  776. Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Kähönen M, Viikari J, Hengstenberg C, Nelson CP, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Völzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Polašek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, März W, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tönjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet. 2013 Feb; 45(2):145-54. PMID: 23263486; PMCID: PMC3663712.
  777. Hancock DB, Soler Artigas M, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, Zhai G, Zhao JH, Aschard H, Burkart KM, Curjuric I, Eijgelsheim M, Elliott P, Gu X, Harris TB, Janson C, Homuth G, Hysi PG, Liu JZ, Loehr LR, Lohman K, Loos RJ, Manning AK, Marciante KD, Obeidat M, Postma DS, Aldrich MC, Brusselle GG, Chen TH, Eiriksdottir G, Franceschini N, Heinrich J, Rotter JI, Wijmenga C, Williams OD, Bentley AR, Hofman A, Laurie CC, Lumley T, Morrison AC, Joubert BR, Rivadeneira F, Couper DJ, Kritchevsky SB, Liu Y, Wjst M, Wain LV, Vonk JM, Uitterlinden AG, Rochat T, Rich SS, Psaty BM, O'Connor GT, North KE, Mirel DB, Meibohm B, Launer LJ, Khaw KT, Hartikainen AL, Hammond CJ, Gläser S, Marchini J, Kraft P, Wareham NJ, Völzke H, Stricker BH, Spector TD, Probst-Hensch NM, Jarvis D, Jarvelin MR, Heckbert SR, Gudnason V, Boezen HM, Barr RG, Cassano PA, Strachan DP, Fornage M, Hall IP, Dupuis J, Tobin MD, London SJ. Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. PLoS Genet. 2012; 8(12):e1003098. PMID: 23284291; PMCID: PMC3527213.
  778. Nettleton JA, Hivert MF, Lemaitre RN, McKeown NM, Mozaffarian D, Tanaka T, Wojczynski MK, Hruby A, Djoussé L, Ngwa JS, Follis JL, Dimitriou M, Ganna A, Houston DK, Kanoni S, Mikkilä V, Manichaikul A, Ntalla I, Renström F, Sonestedt E, van Rooij FJ, Bandinelli S, de Koning L, Ericson U, Hassanali N, Kiefte-de Jong JC, Lohman KK, Raitakari O, Papoutsakis C, Sjogren P, Stirrups K, Ax E, Deloukas P, Groves CJ, Jacques PF, Johansson I, Liu Y, McCarthy MI, North K, Viikari J, Zillikens MC, Dupuis J, Hofman A, Kolovou G, Mukamal K, Prokopenko I, Rolandsson O, Seppälä I, Cupples LA, Hu FB, Kähönen M, Uitterlinden AG, Borecki IB, Ferrucci L, Jacobs DR, Kritchevsky SB, Orho-Melander M, Pankow JS, Lehtimäki T, Witteman JC, Ingelsson E, Siscovick DS, Dedoussis G, Meigs JB, Franks PW. Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. Am J Epidemiol. 2013 Jan 15; 177(2):103-15. PMID: 23255780; PMCID: PMC3707424.
  779. Flink IJ, Jansen PW, Beirens TM, Tiemeier H, van IJzendoorn MH, Jaddoe VW, Hofman A, Raat H. Differences in problem behaviour among ethnic minority and majority preschoolers in the Netherlands and the role of family functioning and parenting factors as mediators: the Generation R Study. BMC Public Health. 2012 Dec 19; 12:1092. PMID: 23253397; PMCID: PMC3577476.
  780. Tharner A, Dierckx B, Luijk MP, van Ijzendoorn MH, Bakermans-Kranenburg MJ, van Ginkel JR, Moll HA, Jaddoe VW, Hofman A, Hudziak JJ, Verhulst FC, Tiemeier H. Attachment disorganization moderates the effect of maternal postnatal depressive symptoms on infant autonomic functioning. Psychophysiology. 2013 Feb; 50(2):195-203. PMID: 23252764.
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  781. Bos D, Ikram MA, Isaacs A, Verhaaren BF, Hofman A, van Duijn CM, Witteman JC, van der Lugt A, Vernooij MW. Genetic loci for coronary calcification and serum lipids relate to aortic and carotid calcification. Circ Cardiovasc Genet. 2013 Feb; 6(1):47-53. PMID: 23247144.
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  782. Singaraja RR, Sivapalaratnam S, Hovingh K, Dubé MP, Castro-Perez J, Collins HL, Adelman SJ, Riwanto M, Manz J, Hubbard B, Tietjen I, Wong K, Mitnaul LJ, van Heek M, Lin L, Roddy TA, McEwen J, Dallinge-Thie G, van Vark-van der Zee L, Verwoert G, Winther M, van Duijn C, Hofman A, Trip MD, Marais AD, Asztalos B, Landmesser U, Sijbrands E, Kastelein JJ, Hayden MR. The impact of partial and complete loss-of-function mutations in endothelial lipase on high-density lipoprotein levels and functionality in humans. Circ Cardiovasc Genet. 2013 Feb; 6(1):54-62. PMID: 23243195.
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  783. Springelkamp H, Lee K, Ramdas WD, Vingerling JR, Hofman A, Klaver CC, Sonka M, Abràmoff MD, Jansonius NM. Optimizing the information yield of 3-D OCT in glaucoma. Invest Ophthalmol Vis Sci. 2012 Dec 13; 53(13):8162-71. PMID: 23154462; PMCID: PMC3522440.
  784. Richardson K, Nettleton JA, Rotllan N, Tanaka T, Smith CE, Lai CQ, Parnell LD, Lee YC, Lahti J, Lemaitre RN, Manichaikul A, Keller M, Mikkilä V, Ngwa J, van Rooij FJ, Ballentyne CM, Borecki IB, Cupples LA, Garcia M, Hofman A, Ferrucci L, Mozaffarian D, Perälä MM, Raitakari O, Tracy RP, Arnett DK, Bandinelli S, Boerwinkle E, Eriksson JG, Franco OH, Kähönen M, Nalls M, Siscovick DS, Houston DK, Psaty BM, Viikari J, Witteman JC, Goodarzi MO, Lehtimäki T, Liu Y, Zillikens MC, Chen YD, Uitterlinden AG, Rotter JI, Fernandez-Hernando C, Ordovas JM. Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. Am J Hum Genet. 2013 Jan 10; 92(1):5-14. PMID: 23246289; PMCID: PMC3542456.
  785. Sonnenschein-van der Voort AM, de Kluizenaar Y, Jaddoe VW, Gabriele C, Raat H, Moll HA, Hofman A, Pierik FH, Miedema HM, de Jongste JC, Duijts L. Air pollution, fetal and infant tobacco smoke exposure, and wheezing in preschool children: a population-based prospective birth cohort. Environ Health. 2012 Dec 11; 11:91. PMID: 23231783; PMCID: PMC3533997.
  786. van Kempen BJ, Ferket BS, Hofman A, Steyerberg EW, Colkesen EB, Boekholdt SM, Wareham NJ, Khaw KT, Hunink MG. Validation of a model to investigate the effects of modifying cardiovascular disease (CVD) risk factors on the burden of CVD: the rotterdam ischemic heart disease and stroke computer simulation (RISC) model. BMC Med. 2012 Dec 06; 10:158. PMID: 23217019; PMCID: PMC3566939.
  787. Selwaness M, van den Bouwhuijsen QJ, Verwoert GC, Dehghan A, Mattace-Raso FU, Vernooij M, Franco OH, Hofman A, van der Lugt A, Wentzel JJ, Witteman JC. Blood pressure parameters and carotid intraplaque hemorrhage as measured by magnetic resonance imaging: The Rotterdam Study. Hypertension. 2013 Jan; 61(1):76-81. PMID: 23213192.
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  788. Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, Kaakinen M, Cousminer DL, Lehtimäki T, Kreiner-Møller E, Warrington NM, Bustamante M, Feenstra B, Berry DJ, Thiering E, Pfab T, Barton SJ, Shields BM, Kerkhof M, van Leeuwen EM, Fulford AJ, Kutalik Z, Zhao JH, den Hoed M, Mahajan A, Lindi V, Goh LK, Hottenga JJ, Wu Y, Raitakari OT, Harder MN, Meirhaeghe A, Ntalla I, Salem RM, Jameson KA, Zhou K, Monies DM, Lagou V, Kirin M, Heikkinen J, Adair LS, Alkuraya FS, Al-Odaib A, Amouyel P, Andersson EA, Bennett AJ, Blakemore AI, Buxton JL, Dallongeville J, Das S, de Geus EJ, Estivill X, Flexeder C, Froguel P, Geller F, Godfrey KM, Gottrand F, Groves CJ, Hansen T, Hirschhorn JN, Hofman A, Hollegaard MV, Hougaard DM, Hyppönen E, Inskip HM, Isaacs A, Jørgensen T, Kanaka-Gantenbein C, Kemp JP, Kiess W, Kilpeläinen TO, Klopp N, Knight BA, Kuzawa CW, McMahon G, Newnham JP, Niinikoski H, Oostra BA, Pedersen L, Postma DS, Ring SM, Rivadeneira F, Robertson NR, Sebert S, Simell O, Slowinski T, Tiesler CM, Tönjes A, Vaag A, Viikari JS, Vink JM, Vissing NH, Wareham NJ, Willemsen G, Witte DR, Zhang H, Zhao J, Wilson JF, Stumvoll M, Prentice AM, Meyer BF, Pearson ER, Boreham CA, Cooper C, Gillman MW, Dedoussis GV, Moreno LA, Pedersen O, Saarinen M, Mohlke KL, Boomsma DI, Saw SM, Lakka TA, Körner A, Loos RJ, Ong KK, Vollenweider P, van Duijn CM, Koppelman GH, Hattersley AT, Holloway JW, Hocher B, Heinrich J, Power C, Melbye M, Guxens M, Pennell CE, Bønnelykke K, Bisgaard H, Eriksson JG, Widén E, Hakonarson H, Uitterlinden AG, Pouta A, Lawlor DA, Smith GD, Frayling TM, McCarthy MI, Grant SF, Jaddoe VW, Jarvelin MR, Timpson NJ, Prokopenko I, Freathy RM. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet. 2013 Jan; 45(1):76-82. PMID: 23202124; PMCID: PMC3605762.
  789. Marcus MW, Müskens RP, Ramdas WD, Wolfs RC, De Jong PT, Vingerling JR, Hofman A, Stricker BH, Jansonius NM. Corticosteroids and open-angle glaucoma in the elderly: a population-based cohort study. Drugs Aging. 2012 Dec; 29(12):963-70. PMID: 23150239.
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  790. van Schie RM, Wessels JA, Verhoef TI, Schalekamp T, le Cessie S, van der Meer FJ, Rosendaal FR, Visser LE, Teichert M, Hofman A, Buhre PN, de Boer A, Maitland-van der Zee AH. Evaluation of the effect of genetic variations in GATA-4 on the phenprocoumon and acenocoumarol maintenance dose. Pharmacogenomics. 2012 Dec; 13(16):1917-23. PMID: 23215884.
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  791. Herba CM, Roza S, Govaert P, Hofman A, Jaddoe V, Verhulst FC, Tiemeier H. Breastfeeding and early brain development: the Generation R study. Matern Child Nutr. 2013 Jul; 9(3):332-49. PMID: 23167730.
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  792. Gertow K, Sennblad B, Strawbridge RJ, Ohrvik J, Zabaneh D, Shah S, Veglia F, Fava C, Kavousi M, McLachlan S, Kivimäki M, Bolton JL, Folkersen L, Gigante B, Leander K, Vikström M, Larsson M, Silveira A, Deanfield J, Voight BF, Fontanillas P, Sabater-Lleal M, Colombo GI, Kumari M, Langenberg C, Wareham NJ, Uitterlinden AG, Gabrielsen A, Hedin U, Franco-Cereceda A, Nyyssönen K, Rauramaa R, Tuomainen TP, Savonen K, Smit AJ, Giral P, Mannarino E, Robertson CM, Talmud PJ, Hedblad B, Hofman A, Erdmann J, Reilly MP, O'Donnell CJ, Farrall M, Clarke R, Franzosi MG, Seedorf U, Syvänen AC, Hansson GK, Eriksson P, Samani NJ, Watkins H, Price JF, Hingorani AD, Melander O, Witteman JC, Baldassarre D, Tremoli E, de Faire U, Humphries SE, Hamsten A. Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk. Circ Cardiovasc Genet. 2012 Dec; 5(6):656-65. PMID: 23152477.
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  793. Krijthe BP, de Jong FH, Hofman A, Franco OH, Witteman JC, Stricker BH, Heeringa J. Dehydroepiandrosterone sulfate levels and risk of atrial fibrillation: the Rotterdam Study. Eur J Prev Cardiol. 2014 Mar; 21(3):291-8. PMID: 23152363.
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  794. Jonsson T, Stefansson H, Steinberg S, Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S, Huttenlocher J, Levey AI, Lah JJ, Rujescu D, Hampel H, Giegling I, Andreassen OA, Engedal K, Ulstein I, Djurovic S, Ibrahim-Verbaas C, Hofman A, Ikram MA, van Duijn CM, Thorsteinsdottir U, Kong A, Stefansson K. Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med. 2013 Jan 10; 368(2):107-16. PMID: 23150908; PMCID: PMC3677583.
  795. Velders FP, De Wit JE, Jansen PW, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. FTO at rs9939609, food responsiveness, emotional control and symptoms of ADHD in preschool children. PLoS One. 2012; 7(11):e49131. PMID: 23155456; PMCID: PMC3498333.
  796. Saavedra Perez HC, Direk N, Hofman A, Vernooij MW, Tiemeier H, Ikram MA. Silent brain infarcts: a cause of depression in the elderly? Psychiatry Res. 2013 Feb 28; 211(2):180-2. PMID: 23154097.
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  797. Medici M, Timmermans S, Visser W, de Muinck Keizer-Schrama SM, Jaddoe VW, Hofman A, Hooijkaas H, de Rijke YB, Tiemeier H, Bongers-Schokking JJ, Visser TJ, Peeters RP, Steegers EA. Maternal thyroid hormone parameters during early pregnancy and birth weight: the Generation R Study. J Clin Endocrinol Metab. 2013 Jan; 98(1):59-66. PMID: 23150694.
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  798. Kiefte-de Jong JC, de Vries JH, Franco OH, Jaddoe VW, Hofman A, Raat H, de Jongste JC, Moll HA. Fish consumption in infancy and asthma-like symptoms at preschool age. Pediatrics. 2012 Dec; 130(6):1060-8. PMID: 23147966.
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  799. Lahousse L, van den Bouwhuijsen QJ, Loth DW, Joos GF, Hofman A, Witteman JC, van der Lugt A, Brusselle GG, Stricker BH. Chronic obstructive pulmonary disease and lipid core carotid artery plaques in the elderly: the Rotterdam Study. Am J Respir Crit Care Med. 2013 Jan 01; 187(1):58-64. PMID: 23144329.
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  800. Heppe DH, Kiefte-de Jong JC, Durmus B, Moll HA, Raat H, Hofman A, Jaddoe VW. Parental, fetal, and infant risk factors for preschool overweight: the Generation R Study. Pediatr Res. 2013 Jan; 73(1):120-7. PMID: 23138398.
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  801. de Schepper EI, Damen J, Bos PK, Hofman A, Koes BW, Bierma-Zeinstra SM. Disk degeneration of the upper lumbar disks is associated with hip pain. Eur Spine J. 2013 Apr; 22(4):721-6. PMID: 23135791; PMCID: PMC3631034.
  802. Lahousse L, Loth DW, Joos GF, Hofman A, Leufkens HG, Brusselle GG, Stricker BH. Statins, systemic inflammation and risk of death in COPD: the Rotterdam study. Pulm Pharmacol Ther. 2013 Apr; 26(2):212-7. PMID: 23142156.
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  804. Jansen PW, Roza SJ, Jaddoe VW, Mackenbach JD, Raat H, Hofman A, Verhulst FC, Tiemeier H. Children's eating behavior, feeding practices of parents and weight problems in early childhood: results from the population-based Generation R Study. Int J Behav Nutr Phys Act. 2012 Oct 30; 9:130. PMID: 23110748; PMCID: PMC3543222.
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  806. Jaddoe VW, van Duijn CM, Franco OH, van der Heijden AJ, van Iizendoorn MH, de Jongste JC, van der Lugt A, Mackenbach JP, Moll HA, Raat H, Rivadeneira F, Steegers EA, Tiemeier H, Uitterlinden AG, Verhulst FC, Hofman A. The Generation R Study: design and cohort update 2012. Eur J Epidemiol. 2012 Sep; 27(9):739-56. PMID: 23086283.
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  807. Medici M, Ikram MA, van der Lijn F, den Heijer T, Vernooij MW, Hofman A, Niessen WJ, Visser TJ, Breteler MM, Peeters RP. The thyroid hormone receptor alpha locus and white matter lesions: a role for the clock gene REV-ERBa. Thyroid. 2012 Nov; 22(11):1181-6. PMID: 23083441; PMCID: PMC3487114.
  808. van Mil NH, Tiemeier H, Bongers-Schokking JJ, Ghassabian A, Hofman A, Hooijkaas H, Jaddoe VW, de Muinck Keizer-Schrama SM, Steegers EA, Visser TJ, Visser W, Ross HA, Verhulst FC, de Rijke YB, Steegers-Theunissen RP. Low urinary iodine excretion during early pregnancy is associated with alterations in executive functioning in children. J Nutr. 2012 Dec; 142(12):2167-74. PMID: 23077186.
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  809. Jacobs LC, Wollstein A, Lao O, Hofman A, Klaver CC, Uitterlinden AG, Nijsten T, Kayser M, Liu F. Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans. Hum Genet. 2013 Feb; 132(2):147-58. PMID: 23052946.
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  811. Kaptoge S, Di Angelantonio E, Pennells L, Wood AM, White IR, Gao P, Walker M, Thompson A, Sarwar N, Caslake M, Butterworth AS, Amouyel P, Assmann G, Bakker SJ, Barr EL, Barrett-Connor E, Benjamin EJ, Björkelund C, Brenner H, Brunner E, Clarke R, Cooper JA, Cremer P, Cushman M, Dagenais GR, D'Agostino RB, Dankner R, Davey-Smith G, Deeg D, Dekker JM, Engström G, Folsom AR, Fowkes FG, Gallacher J, Gaziano JM, Giampaoli S, Gillum RF, Hofman A, Howard BV, Ingelsson E, Iso H, Jørgensen T, Kiechl S, Kitamura A, Kiyohara Y, Koenig W, Kromhout D, Kuller LH, Lawlor DA, Meade TW, Nissinen A, Nordestgaard BG, Onat A, Panagiotakos DB, Psaty BM, Rodriguez B, Rosengren A, Salomaa V, Kauhanen J, Salonen JT, Shaffer JA, Shea S, Ford I, Stehouwer CD, Strandberg TE, Tipping RW, Tosetto A, Wassertheil-Smoller S, Wennberg P, Westendorp RG, Whincup PH, Wilhelmsen L, Woodward M, Lowe GD, Wareham NJ, Khaw KT, Sattar N, Packard CJ, Gudnason V, Ridker PM, Pepys MB, Thompson SG, Danesh J. C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med. 2012 Oct 04; 367(14):1310-20. PMID: 23034020; PMCID: PMC3714101.
  812. Franco OH, Hofman A. The future of preventive medicine: polypill prescriptions in the context of Plato's physical perspective. Prev Med. 2012 Dec; 55(6):550-1. PMID: 23041429.
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  813. Wieberdink RG, Koudstaal PJ, Hofman A, Witteman JC, Breteler MM, Ikram MA. Insulin resistance and the risk of stroke and stroke subtypes in the nondiabetic elderly. Am J Epidemiol. 2012 Oct 15; 176(8):699-707. PMID: 23035021.
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  814. Mackenbach JD, Tiemeier H, Ende Jv, Nijs IM, Jaddoe VW, Hofman A, Verhulst FC, Jansen PW. Relation of emotional and behavioral problems with body mass index in preschool children: the Generation R study. J Dev Behav Pediatr. 2012 Oct; 33(8):641-8. PMID: 23027138.
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  815. Verlinden M, Tiemeier H, Hudziak JJ, Jaddoe VW, Raat H, Guxens M, Hofman A, Verhulst FC, Jansen PW. Television viewing and externalizing problems in preschool children: the Generation R Study. Arch Pediatr Adolesc Med. 2012 Oct; 166(10):919-25. PMID: 22869354.
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  816. Liu CT, Estrada K, Yerges-Armstrong LM, Amin N, Evangelou E, Li G, Minster RL, Carless MA, Kammerer CM, Oei L, Zhou Y, Alonso N, Dailiana Z, Eriksson J, García-Giralt N, Giroux S, Husted LB, Khusainova RI, Koromila T, Kung AW, Lewis JR, Masi L, Mencej-Bedrac S, Nogues X, Patel MS, Prezelj J, Richards JB, Sham PC, Spector T, Vandenput L, Xiao SM, Zheng HF, Zhu K, Balcells S, Brandi ML, Frost M, Goltzman D, González-Macías J, Karlsson M, Khusnutdinova EK, Kollia P, Langdahl BL, Ljunggren O, Lorentzon M, Marc J, Mellström D, Ohlsson C, Olmos JM, Ralston SH, Riancho JA, Rousseau F, Urreizti R, Van Hul W, Zarrabeitia MT, Castano-Betancourt M, Demissie S, Grundberg E, Herrera L, Kwan T, Medina-Gómez C, Pastinen T, Sigurdsson G, Thorleifsson G, Vanmeurs JB, Blangero J, Hofman A, Liu Y, Mitchell BD, O'Connell JR, Oostra BA, Rotter JI, Stefansson K, Streeten EA, Styrkarsdottir U, Thorsteinsdottir U, Tylavsky FA, Uitterlinden A, Cauley JA, Harris TB, Ioannidis JP, Psaty BM, Robbins JA, Zillikens MC, Vanduijn CM, Prince RL, Karasik D, Rivadeneira F, Kiel DP, Cupples LA, Hsu YH. Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res. 2012 Oct; 27(10):2051-64. PMID: 22692763; PMCID: PMC3447125.
  817. Tiemeier H, Velders FP, Szekely E, Roza SJ, Dieleman G, Jaddoe VW, Uitterlinden AG, White TJ, Bakermans-Kranenburg MJ, Hofman A, Van Ijzendoorn MH, Hudziak JJ, Verhulst FC. The Generation R Study: a review of design, findings to date, and a study of the 5-HTTLPR by environmental interaction from fetal life onward. J Am Acad Child Adolesc Psychiatry. 2012 Nov; 51(11):1119-1135.e7. PMID: 23101739.
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  818. Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, Okada Y, Polasek O, Westra HJ, Wang YA, Del Greco M F, Glazer NL, Kapur K, Kema IP, Lopez LM, Schillert A, Smith AV, Winkler CA, Zgaga L, Bandinelli S, Bergmann S, Boban M, Bochud M, Chen YD, Davies G, Dehghan A, Ding J, Doering A, Durda JP, Ferrucci L, Franco OH, Franke L, Gunjaca G, Hofman A, Hsu FC, Kolcic I, Kraja A, Kubo M, Lackner KJ, Launer L, Loehr LR, Li G, Meisinger C, Nakamura Y, Schwienbacher C, Starr JM, Takahashi A, Torlak V, Uitterlinden AG, Vitart V, Waldenberger M, Wild PS, Kirin M, Zeller T, Zemunik T, Zhang Q, Ziegler A, Blankenberg S, Boerwinkle E, Borecki IB, Campbell H, Deary IJ, Frayling TM, Gieger C, Harris TB, Hicks AA, Koenig W, O' Donnell CJ, Fox CS, Pramstaller PP, Psaty BM, Reiner AP, Rotter JI, Rudan I, Snieder H, Tanaka T, van Duijn CM, Vollenweider P, Waeber G, Wilson JF, Witteman JC, Wolffenbuttel BH, Wright AF, Wu Q, Liu Y, Jenny NS, North KE, Felix JF, Alizadeh BZ, Cupples LA, Perry JR, Morris AP. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet. 2012 Oct 05; 91(4):744-53. PMID: 23022100; PMCID: PMC3484648.
  819. Lambregtse-van den Berg MP, Lucassen N, Kuipers-Nap MF, Dingemans PM, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Assessing expressed emotion during pregnancy. Psychiatry Res. 2013 Feb 28; 205(3):285-8. PMID: 23021321.
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  820. Langeslag SJ, Schmidt M, Ghassabian A, Jaddoe VW, Hofman A, van der Lugt A, Verhulst FC, Tiemeier H, White TJ. Functional connectivity between parietal and frontal brain regions and intelligence in young children: the Generation R study. Hum Brain Mapp. 2013 Dec; 34(12):3299-307. PMID: 23008156.
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  821. Williams FM, Bansal AT, van Meurs JB, Bell JT, Meulenbelt I, Suri P, Rivadeneira F, Sambrook PN, Hofman A, Bierma-Zeinstra S, Menni C, Kloppenburg M, Slagboom PE, Hunter DJ, MacGregor AJ, Uitterlinden AG, Spector TD. Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects. Ann Rheum Dis. 2013 Jul; 72(7):1141-8. PMID: 22993228; PMCID: PMC3686263.
  822. Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD, Smith NL, Williams SM, Ikram MA, Kleber ME, Becker DM, Truong V, Mychaleckyj JC, Tang W, Yang Q, Sennblad B, Moore JH, Williams FM, Dehghan A, Silbernagel G, Schrijvers EM, Smith S, Karakas M, Tofler GH, Silveira A, Navis GJ, Lohman K, Chen MH, Peters A, Goel A, Hopewell JC, Chambers JC, Saleheen D, Lundmark P, Psaty BM, Strawbridge RJ, Boehm BO, Carter AM, Meisinger C, Peden JF, Bis JC, McKnight B, Öhrvik J, Taylor K, Franzosi MG, Seedorf U, Collins R, Franco-Cereceda A, Syvänen AC, Goodall AH, Yanek LR, Cushman M, Müller-Nurasyid M, Folsom AR, Basu S, Matijevic N, van Gilst WH, Kooner JS, Hofman A, Danesh J, Clarke R, Meigs JB, Kathiresan S, Reilly MP, Klopp N, Harris TB, Winkelmann BR, Grant PJ, Hillege HL, Watkins H, Spector TD, Becker LC, Tracy RP, März W, Uitterlinden AG, Eriksson P, Cambien F, Morange PE, Koenig W, Soranzo N, van der Harst P, Liu Y, O'Donnell CJ, Hamsten A. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood. 2012 Dec 06; 120(24):4873-81. PMID: 22990020; PMCID: PMC3520624.
  823. Koller MT, Leening MJ, Wolbers M, Steyerberg EW, Hunink MG, Schoop R, Hofman A, Bucher HC, Psaty BM, Lloyd-Jones DM, Witteman JC. Development and validation of a coronary risk prediction model for older U.S. and European persons in the Cardiovascular Health Study and the Rotterdam Study. Ann Intern Med. 2012 Sep 18; 157(6):389-97. PMID: 22986376; PMCID: PMC3644640.
  824. Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R, Waite L, Smith AV, Yerges-Armstrong LM, Monda KL, Hadley D, Mahajan A, Li G, Kapur K, Vitart V, Huffman JE, Wang SR, Palmer C, Esko T, Fischer K, Zhao JH, Demirkan A, Isaacs A, Feitosa MF, Luan J, Heard-Costa NL, White C, Jackson AU, Preuss M, Ziegler A, Eriksson J, Kutalik Z, Frau F, Nolte IM, Van Vliet-Ostaptchouk JV, Hottenga JJ, Jacobs KB, Verweij N, Goel A, Medina-Gomez C, Estrada K, Bragg-Gresham JL, Sanna S, Sidore C, Tyrer J, Teumer A, Prokopenko I, Mangino M, Lindgren CM, Assimes TL, Shuldiner AR, Hui J, Beilby JP, McArdle WL, Hall P, Haritunians T, Zgaga L, Kolcic I, Polasek O, Zemunik T, Oostra BA, Junttila MJ, Grönberg H, Schreiber S, Peters A, Hicks AA, Stephens J, Foad NS, Laitinen J, Pouta A, Kaakinen M, Willemsen G, Vink JM, Wild SH, Navis G, Asselbergs FW, Homuth G, John U, Iribarren C, Harris T, Launer L, Gudnason V, O'Connell JR, Boerwinkle E, Cadby G, Palmer LJ, James AL, Musk AW, Ingelsson E, Psaty BM, Beckmann JS, Waeber G, Vollenweider P, Hayward C, Wright AF, Rudan I, Groop LC, Metspalu A, Khaw KT, van Duijn CM, Borecki IB, Province MA, Wareham NJ, Tardif JC, Huikuri HV, Cupples LA, Atwood LD, Fox CS, Boehnke M, Collins FS, Mohlke KL, Erdmann J, Schunkert H, Hengstenberg C, Stark K, Lorentzon M, Ohlsson C, Cusi D, Staessen JA, Van der Klauw MM, Pramstaller PP, Kathiresan S, Jolley JD, Ripatti S, Jarvelin MR, de Geus EJ, Boomsma DI, Penninx B, Wilson JF, Campbell H, Chanock SJ, van der Harst P, Hamsten A, Watkins H, Hofman A, Witteman JC, Zillikens MC, Uitterlinden AG, Rivadeneira F, Zillikens MC, Kiemeney LA, Vermeulen SH, Abecasis GR, Schlessinger D, Schipf S, Stumvoll M, Tönjes A, Spector TD, North KE, Lettre G, McCarthy MI, Berndt SI, Heath AC, Madden PA, Nyholt DR, Montgomery GW, Martin NG, McKnight B, Strachan DP, Hill WG, Snieder H, Ridker PM, Thorsteinsdottir U, Stefansson K, Frayling TM, Hirschhorn JN, Goddard ME, Visscher PM. FTO genotype is associated with phenotypic variability of body mass index. Nature. 2012 Oct 11; 490(7419):267-72. PMID: 22982992; PMCID: PMC3564953.
  825. Liu F, van der Lijn F, Schurmann C, Zhu G, Chakravarty MM, Hysi PG, Wollstein A, Lao O, de Bruijne M, Ikram MA, van der Lugt A, Rivadeneira F, Uitterlinden AG, Hofman A, Niessen WJ, Homuth G, de Zubicaray G, McMahon KL, Thompson PM, Daboul A, Puls R, Hegenscheid K, Bevan L, Pausova Z, Medland SE, Montgomery GW, Wright MJ, Wicking C, Boehringer S, Spector TD, Paus T, Martin NG, Biffar R, Kayser M. A genome-wide association study identifies five loci influencing facial morphology in Europeans. PLoS Genet. 2012 Sep; 8(9):e1002932. PMID: 23028347; PMCID: PMC3441666.
  826. Oosterveer DM, Versmissen J, Defesche JC, Sivapalaratnam S, Yazdanpanah M, Mulder M, van der Zee L, Uitterlinden AG, van Duijn CM, Hofman A, Kastelein JJ, Aulchenko YS, Sijbrands EJ. Low-density lipoprotein receptor mutations generate synthetic genome-wide associations. Eur J Hum Genet. 2013 May; 21(5):563-6. PMID: 22968135; PMCID: PMC3641383.
  827. Ertel KA, Kleinman K, van Rossem L, Sagiv S, Tiemeier H, Hofman A, Jaddoe VW, Raat H. Maternal perinatal depression is not independently associated with child body mass index in the Generation R Study: methods and missing data matter. J Clin Epidemiol. 2012 Dec; 65(12):1300-9. PMID: 22974499.
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  829. Peters MJ, Broer L, Willemen HL, Eiriksdottir G, Hocking LJ, Holliday KL, Horan MA, Meulenbelt I, Neogi T, Popham M, Schmidt CO, Soni A, Valdes AM, Amin N, Dennison EM, Eijkelkamp N, Harris TB, Hart DJ, Hofman A, Huygen FJ, Jameson KA, Jones GT, Launer LJ, Kerkhof HJ, de Kruijf M, McBeth J, Kloppenburg M, Ollier WE, Oostra B, Payton A, Rivadeneira F, Smith BH, Smith AV, Stolk L, Teumer A, Thomson W, Uitterlinden AG, Wang K, van Wingerden SH, Arden NK, Cooper C, Felson D, Gudnason V, Macfarlane GJ, Pendleton N, Slagboom PE, Spector TD, Völzke H, Kavelaars A, van Duijn CM, Williams FM, van Meurs JB. Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region. Ann Rheum Dis. 2013 Mar; 72(3):427-36. PMID: 22956598; PMCID: PMC3691951.
  830. Tyrrell J, Huikari V, Christie JT, Cavadino A, Bakker R, Brion MJ, Geller F, Paternoster L, Myhre R, Potter C, Johnson PC, Ebrahim S, Feenstra B, Hartikainen AL, Hattersley AT, Hofman A, Kaakinen M, Lowe LP, Magnus P, McConnachie A, Melbye M, Ng JW, Nohr EA, Power C, Ring SM, Sebert SP, Sengpiel V, Taal HR, Watt GC, Sattar N, Relton CL, Jacobsson B, Frayling TM, Sørensen TI, Murray JC, Lawlor DA, Pennell CE, Jaddoe VW, Hypponen E, Lowe WL, Jarvelin MR, Davey Smith G, Freathy RM. Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight. Hum Mol Genet. 2012 Dec 15; 21(24):5344-58. PMID: 22956269; PMCID: PMC3516066.
  831. Visser AM, Jaddoe VW, Ghassabian A, Schenk JJ, Verhulst FC, Hofman A, Tiemeier H, Moll HA, Arts WF. Febrile seizures and behavioural and cognitive outcomes in preschool children: the Generation R study. Dev Med Child Neurol. 2012 Nov; 54(11):1006-11. PMID: 22937894.
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  832. Leening MJ, Elias-Smale SE, Kavousi M, Felix JF, Deckers JW, Vliegenthart R, Oudkerk M, Hofman A, Steyerberg EW, Stricker BH, Witteman JC. Coronary calcification and the risk of heart failure in the elderly: the Rotterdam Study. JACC Cardiovasc Imaging. 2012 Sep; 5(9):874-80. PMID: 22974798.
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  833. Choté A, de Groot C, Redekop K, Hoefman R, Koopmans G, Jaddoe V, Hofman A, Steegers E, Trappenburg M, Mackenbach J, Foets M. Differences in quality of antenatal care provided by midwives to low-risk pregnant dutch women in different ethnic groups. J Midwifery Womens Health. 2012 Sep-Oct; 57(5):461-8. PMID: 22954076.
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  834. Ghassabian A, Herba CM, Roza SJ, Govaert P, Schenk JJ, Jaddoe VW, Hofman A, White T, Verhulst FC, Tiemeier H. Infant brain structures, executive function, and attention deficit/hyperactivity problems at preschool age. A prospective study. J Child Psychol Psychiatry. 2013 Jan; 54(1):96-104. PMID: 22928649.
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  835. van den Hooven EH, Pierik FH, de Kluizenaar Y, Hofman A, van Ratingen SW, Zandveld PY, Russcher H, Lindemans J, Miedema HM, Steegers EA, Jaddoe VW. Air pollution exposure and markers of placental growth and function: the generation R study. Environ Health Perspect. 2012 Dec; 120(12):1753-9. PMID: 22922820; PMCID: PMC3548279.
  836. Poels MM, Steyerberg EW, Wieberdink RG, Hofman A, Koudstaal PJ, Ikram MA, Breteler MM. Assessment of cerebral small vessel disease predicts individual stroke risk. J Neurol Neurosurg Psychiatry. 2012 Dec; 83(12):1174-9. PMID: 22917672.
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  837. Den Ruijter HM, Peters SA, Anderson TJ, Britton AR, Dekker JM, Eijkemans MJ, Engström G, Evans GW, de Graaf J, Grobbee DE, Hedblad B, Hofman A, Holewijn S, Ikeda A, Kavousi M, Kitagawa K, Kitamura A, Koffijberg H, Lonn EM, Lorenz MW, Mathiesen EB, Nijpels G, Okazaki S, O'Leary DH, Polak JF, Price JF, Robertson C, Rembold CM, Rosvall M, Rundek T, Salonen JT, Sitzer M, Stehouwer CD, Witteman JC, Moons KG, Bots ML. Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis. JAMA. 2012 Aug 22; 308(8):796-803. PMID: 22910757.
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  838. Sikorska K, Rivadeneira F, Groenen PJ, Hofman A, Uitterlinden AG, Eilers PH, Lesaffre E. Fast linear mixed model computations for genome-wide association studies with longitudinal data. Stat Med. 2013 Jan 15; 32(1):165-80. PMID: 22911890.
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  839. Oei L, Rivadeneira F, Ly F, Breda SJ, Zillikens MC, Hofman A, Uitterlinden AG, Krestin GP, Oei EH. Review of radiological scoring methods of osteoporotic vertebral fractures for clinical and research settings. Eur Radiol. 2013 Feb; 23(2):476-86. PMID: 22892721.
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  842. Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, Kanoni S, Kumar A, Lagou V, Langenberg C, Luan J, Lindgren CM, Müller-Nurasyid M, Pechlivanis S, Rayner NW, Scott LJ, Wiltshire S, Yengo L, Kinnunen L, Rossin EJ, Raychaudhuri S, Johnson AD, Dimas AS, Loos RJ, Vedantam S, Chen H, Florez JC, Fox C, Liu CT, Rybin D, Couper DJ, Kao WH, Li M, Cornelis MC, Kraft P, Sun Q, van Dam RM, Stringham HM, Chines PS, Fischer K, Fontanillas P, Holmen OL, Hunt SE, Jackson AU, Kong A, Lawrence R, Meyer J, Perry JR, Platou CG, Potter S, Rehnberg E, Robertson N, Sivapalaratnam S, Stancáková A, Stirrups K, Thorleifsson G, Tikkanen E, Wood AR, Almgren P, Atalay M, Benediktsson R, Bonnycastle LL, Burtt N, Carey J, Charpentier G, Crenshaw AT, Doney AS, Dorkhan M, Edkins S, Emilsson V, Eury E, Forsen T, Gertow K, Gigante B, Grant GB, Groves CJ, Guiducci C, Herder C, Hreidarsson AB, Hui J, James A, Jonsson A, Rathmann W, Klopp N, Kravic J, Krjutškov K, Langford C, Leander K, Lindholm E, Lobbens S, Männistö S, Mirza G, Mühleisen TW, Musk B, Parkin M, Rallidis L, Saramies J, Sennblad B, Shah S, Sigurðsson G, Silveira A, Steinbach G, Thorand B, Trakalo J, Veglia F, Wennauer R, Winckler W, Zabaneh D, Campbell H, van Duijn C, Uitterlinden AG, Hofman A, Sijbrands E, Abecasis GR, Owen KR, Zeggini E, Trip MD, Forouhi NG, Syvänen AC, Eriksson JG, Peltonen L, Nöthen MM, Balkau B, Palmer CN, Lyssenko V, Tuomi T, Isomaa B, Hunter DJ, Qi L, Shuldiner AR, Roden M, Barroso I, Wilsgaard T, Beilby J, Hovingh K, Price JF, Wilson JF, Rauramaa R, Lakka TA, Lind L, Dedoussis G, Njølstad I, Pedersen NL, Khaw KT, Wareham NJ, Keinanen-Kiukaanniemi SM, Saaristo TE, Korpi-Hyövälti E, Saltevo J, Laakso M, Kuusisto J, Metspalu A, Collins FS, Mohlke KL, Bergman RN, Tuomilehto J, Boehm BO, Gieger C, Hveem K, Cauchi S, Froguel P, Baldassarre D, Tremoli E, Humphries SE, Saleheen D, Danesh J, Ingelsson E, Ripatti S, Salomaa V, Erbel R, Jöckel KH, Moebus S, Peters A, Illig T, de Faire U, Hamsten A, Morris AD, Donnelly PJ, Frayling TM, Hattersley AT, Boerwinkle E, Melander O, Kathiresan S, Nilsson PM, Deloukas P, Thorsteinsdottir U, Groop LC, Stefansson K, Hu F, Pankow JS, Dupuis J, Meigs JB, Altshuler D, Boehnke M, McCarthy MI. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012 Sep; 44(9):981-90. PMID: 22885922; PMCID: PMC3442244.
  843. van Mil NH, Steegers-Theunissen RP, Bongers-Schokking JJ, El Marroun H, Ghassabian A, Hofman A, Jaddoe VW, Visser TJ, Verhulst FC, de Rijke YB, Steegers EA, Tiemeier H. Maternal hypothyroxinemia during pregnancy and growth of the fetal and infant head. Reprod Sci. 2012 Dec; 19(12):1315-22. PMID: 22878528.
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  844. Poels MM, Zaccai K, Verwoert GC, Vernooij MW, Hofman A, van der Lugt A, Witteman JC, Breteler MM, Mattace-Raso FU, Ikram MA. Arterial stiffness and cerebral small vessel disease: the Rotterdam Scan Study. Stroke. 2012 Oct; 43(10):2637-42. PMID: 22879099.
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  845. Wijtzes AI, Jansen W, Kamphuis CB, Jaddoe VW, Moll HA, Tiemeier H, Verhulst FC, Hofman A, Mackenbach JP, Raat H. Increased risk of exceeding entertainment-media guidelines in preschool children from low socioeconomic background: the Generation R Study. Prev Med. 2012 Oct; 55(4):325-9. PMID: 22890021.
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  846. Koehler EM, Schouten JN, Hansen BE, van Rooij FJ, Hofman A, Stricker BH, Janssen HL. Prevalence and risk factors of non-alcoholic fatty liver disease in the elderly: results from the Rotterdam study. J Hepatol. 2012 Dec; 57(6):1305-11. PMID: 22871499.
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  847. van Schie RM, el Khedr N, Verhoef TI, Teichert M, Stricker BH, Hofman A, Buhre PN, Wessels JA, Schalekamp T, le Cessie S, van der Meer FJ, Rosendaal FR, de Boer A, Maitland-van der Zee AH, Visser LE. Validation of the acenocoumarol EU-PACT algorithms: similar performance in the Rotterdam Study cohort as in the original study. Pharmacogenomics. 2012 Aug; 13(11):1239-45. PMID: 22920394.
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  848. Li X, Xia M, Ma H, Hofman A, Hu Y, Yan H, He W, Lin H, Jeekel J, Zhao N, Gao J, Gao X. Liver fat content is associated with increased carotid atherosclerosis in a Chinese middle-aged and elderly population: the Shanghai Changfeng study. Atherosclerosis. 2012 Oct; 224(2):480-5. PMID: 22884916.
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  849. Rijlaarsdam J, Stevens GW, van der Ende J, Arends LR, Hofman A, Jaddoe VW, Mackenbach JP, Verhulst FC, Tiemeier H. A brief observational instrument for the assessment of infant home environment: development and psychometric testing. Int J Methods Psychiatr Res. 2012 Sep; 21(3):195-204. PMID: 22836590.
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  850. Boraska V, Jeroncic A, Colonna V, Southam L, Nyholt DR, Rayner NW, Perry JR, Toniolo D, Albrecht E, Ang W, Bandinelli S, Barbalic M, Barroso I, Beckmann JS, Biffar R, Boomsma D, Campbell H, Corre T, Erdmann J, Esko T, Fischer K, Franceschini N, Frayling TM, Girotto G, Gonzalez JR, Harris TB, Heath AC, Heid IM, Hoffmann W, Hofman A, Horikoshi M, Zhao JH, Jackson AU, Hottenga JJ, Jula A, Kähönen M, Khaw KT, Kiemeney LA, Klopp N, Kutalik Z, Lagou V, Launer LJ, Lehtimäki T, Lemire M, Lokki ML, Loley C, Luan J, Mangino M, Mateo Leach I, Medland SE, Mihailov E, Montgomery GW, Navis G, Newnham J, Nieminen MS, Palotie A, Panoutsopoulou K, Peters A, Pirastu N, Polasek O, Rehnström K, Ripatti S, Ritchie GR, Rivadeneira F, Robino A, Samani NJ, Shin SY, Sinisalo J, Smit JH, Soranzo N, Stolk L, Swinkels DW, Tanaka T, Teumer A, Tönjes A, Traglia M, Tuomilehto J, Valsesia A, van Gilst WH, van Meurs JB, Smith AV, Viikari J, Vink JM, Waeber G, Warrington NM, Widen E, Willemsen G, Wright AF, Zanke BW, Zgaga L, Boehnke M, d'Adamo AP, de Geus E, Demerath EW, den Heijer M, Eriksson JG, Ferrucci L, Gieger C, Gudnason V, Hayward C, Hengstenberg C, Hudson TJ, Järvelin MR, Kogevinas M, Loos RJ, Martin NG, Metspalu A, Pennell CE, Penninx BW, Perola M, Raitakari O, Salomaa V, Schreiber S, Schunkert H, Spector TD, Stumvoll M, Uitterlinden AG, Ulivi S, van der Harst P, Vollenweider P, Völzke H, Wareham NJ, Wichmann HE, Wilson JF, Rudan I, Xue Y, Zeggini E. Genome-wide meta-analysis of common variant differences between men and women. Hum Mol Genet. 2012 Nov 01; 21(21):4805-15. PMID: 22843499; PMCID: PMC3471397.
  851. Wilk JB, Shrine NR, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AV, Heckbert SR, Smolonska J, Tang W, Loth DW, Curjuric I, Hui J, Cho MH, Latourelle JC, Henry AP, Aldrich M, Bakke P, Beaty TH, Bentley AR, Borecki IB, Brusselle GG, Burkart KM, Chen TH, Couper D, Crapo JD, Davies G, Dupuis J, Franceschini N, Gulsvik A, Hancock DB, Harris TB, Hofman A, Imboden M, James AL, Khaw KT, Lahousse L, Launer LJ, Litonjua A, Liu Y, Lohman KK, Lomas DA, Lumley T, Marciante KD, McArdle WL, Meibohm B, Morrison AC, Musk AW, Myers RH, North KE, Postma DS, Psaty BM, Rich SS, Rivadeneira F, Rochat T, Rotter JI, Soler Artigas M, Starr JM, Uitterlinden AG, Wareham NJ, Wijmenga C, Zanen P, Province MA, Silverman EK, Deary IJ, Palmer LJ, Cassano PA, Gudnason V, Barr RG, Loos RJ, Strachan DP, London SJ, Boezen HM, Probst-Hensch N, Gharib SA, Hall IP, O'Connor GT, Tobin MD, Stricker BH. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med. 2012 Oct 01; 186(7):622-32. PMID: 22837378; PMCID: PMC3480517.
  852. Mook-Kanamori DO, van Beijsterveldt CE, Steegers EA, Aulchenko YS, Raat H, Hofman A, Eilers PH, Boomsma DI, Jaddoe VW. Heritability estimates of body size in fetal life and early childhood. PLoS One. 2012; 7(7):e39901. PMID: 22848364; PMCID: PMC3405108.
  853. McQuillan R, Eklund N, Pirastu N, Kuningas M, McEvoy BP, Esko T, Corre T, Davies G, Kaakinen M, Lyytikäinen LP, Kristiansson K, Havulinna AS, Gögele M, Vitart V, Tenesa A, Aulchenko Y, Hayward C, Johansson A, Boban M, Ulivi S, Robino A, Boraska V, Igl W, Wild SH, Zgaga L, Amin N, Theodoratou E, Polašek O, Girotto G, Lopez LM, Sala C, Lahti J, Laatikainen T, Prokopenko I, Kals M, Viikari J, Yang J, Pouta A, Estrada K, Hofman A, Freimer N, Martin NG, Kähönen M, Milani L, Heliövaara M, Vartiainen E, Räikkönen K, Masciullo C, Starr JM, Hicks AA, Esposito L, Kolcic I, Farrington SM, Oostra B, Zemunik T, Campbell H, Kirin M, Pehlic M, Faletra F, Porteous D, Pistis G, Widén E, Salomaa V, Koskinen S, Fischer K, Lehtimäki T, Heath A, McCarthy MI, Rivadeneira F, Montgomery GW, Tiemeier H, Hartikainen AL, Madden PA, d'Adamo P, Hastie ND, Gyllensten U, Wright AF, van Duijn CM, Dunlop M, Rudan I, Gasparini P, Pramstaller PP, Deary IJ, Toniolo D, Eriksson JG, Jula A, Raitakari OT, Metspalu A, Perola M, Järvelin MR, Uitterlinden A, Visscher PM, Wilson JF. Evidence of inbreeding depression on human height. PLoS Genet. 2012; 8(7):e1002655. PMID: 22829771; PMCID: PMC3400549.
  854. Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimäki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V, Mangino M, Onland-Moret NC, Chen B, Eriksson J, Garcia M, Liu YM, Koster A, Lohman K, Lyytikäinen LP, Petersen AK, Prescott J, Stolk L, Vandenput L, Wood AR, Zhuang WV, Ruokonen A, Hartikainen AL, Pouta A, Bandinelli S, Biffar R, Brabant G, Cox DG, Chen Y, Cummings S, Ferrucci L, Gunter MJ, Hankinson SE, Martikainen H, Hofman A, Homuth G, Illig T, Jansson JO, Johnson AD, Karasik D, Karlsson M, Kettunen J, Kiel DP, Kraft P, Liu J, Ljunggren Ö, Lorentzon M, Maggio M, Markus MR, Mellström D, Miljkovic I, Mirel D, Nelson S, Morin Papunen L, Peeters PH, Prokopenko I, Raffel L, Reincke M, Reiner AP, Rexrode K, Rivadeneira F, Schwartz SM, Siscovick D, Soranzo N, Stöckl D, Tworoger S, Uitterlinden AG, van Gils CH, Vasan RS, Wichmann HE, Zhai G, Bhasin S, Bidlingmaier M, Chanock SJ, De Vivo I, Harris TB, Hunter DJ, Kähönen M, Liu S, Ouyang P, Spector TD, van der Schouw YT, Viikari J, Wallaschofski H, McCarthy MI, Frayling TM, Murray A, Franks S, Järvelin MR, de Jong FH, Raitakari O, Teumer A, Ohlsson C, Murabito JM, Perry JR. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet. 2012; 8(7):e1002805. PMID: 22829776; PMCID: PMC3400553.
  855. Hafkamp-de Groen E, Mohangoo AD, Landgraf JM, de Jongste JC, Duijts L, Moll HA, Jaddoe VW, Hofman A, Raat H. The impact of preschool wheezing patterns on health-related quality of life at age 4 years. Eur Respir J. 2013 Apr; 41(4):952-9. PMID: 22790911.
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  856. Velders FP, Dieleman G, Cents RA, Bakermans-Kranenburg MJ, Jaddoe VW, Hofman A, Van Ijzendoorn MH, Verhulst FC, Tiemeier H. Variation in the glucocorticoid receptor gene at rs41423247 moderates the effect of prenatal maternal psychological symptoms on child cortisol reactivity and behavior. Neuropsychopharmacology. 2012 Oct; 37(11):2541-9. PMID: 22781842; PMCID: PMC3442349.
  857. Schrijvers EM, Buitendijk GH, Ikram MK, Koudstaal PJ, Hofman A, Vingerling JR, Breteler MM. Retinopathy and risk of dementia: the Rotterdam Study. Neurology. 2012 Jul 24; 79(4):365-70. PMID: 22786586; PMCID: PMC3400091.
  858. Hek K, Direk N, Newson RS, Hofman A, Hoogendijk WJ, Mulder CL, Tiemeier H. Anxiety disorders and salivary cortisol levels in older adults: a population-based study. Psychoneuroendocrinology. 2013 Feb; 38(2):300-5. PMID: 22776419.
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  859. Medina-Gomez C, Kemp JP, Estrada K, Eriksson J, Liu J, Reppe S, Evans DM, Heppe DH, Vandenput L, Herrera L, Ring SM, Kruithof CJ, Timpson NJ, Zillikens MC, Olstad OK, Zheng HF, Richards JB, St Pourcain B, Hofman A, Jaddoe VW, Smith GD, Lorentzon M, Gautvik KM, Uitterlinden AG, Brommage R, Ohlsson C, Tobias JH, Rivadeneira F. Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. PLoS Genet. 2012 Jul; 8(7):e1002718. PMID: 22792070; PMCID: PMC3390371.
  860. Rijlaarsdam J, Tiemeier H, Hofman A, Jaddoe VW, Mackenbach JP, Verhulst FC, Stevens GW. Home environments of infants: relations with child development through age 3. J Epidemiol Community Health. 2013 Jan; 67(1):14-20. PMID: 22766779.
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  861. El Marroun H, Jaddoe VW, Hudziak JJ, Roza SJ, Steegers EA, Hofman A, Verhulst FC, White TJ, Stricker BH, Tiemeier H. Maternal use of selective serotonin reuptake inhibitors, fetal growth, and risk of adverse birth outcomes. Arch Gen Psychiatry. 2012 Jul; 69(7):706-14. PMID: 22393202.
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  862. Bouthoorn SH, van Lenthe FJ, Hokken-Koelega AC, Moll HA, Tiemeier H, Hofman A, Mackenbach JP, Jaddoe VW, Raat H. Head circumference of infants born to mothers with different educational levels; the Generation R Study. PLoS One. 2012; 7(6):e39798. PMID: 22768125; PMCID: PMC3387269.
  863. Snijder CA, Brand T, Jaddoe V, Hofman A, Mackenbach JP, Steegers EA, Burdorf A. Physically demanding work, fetal growth and the risk of adverse birth outcomes. The Generation R Study. Occup Environ Med. 2012 Aug; 69(8):543-50. PMID: 22744766.
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  864. Marcus MW, Müskens RP, Ramdas WD, Wolfs RC, de Jong PT, Vingerling JR, Hofman A, Stricker BH, Jansonius NM. Antithrombotic medication and incident open-angle glaucoma. Invest Ophthalmol Vis Sci. 2012 Jun 20; 53(7):3801-5. PMID: 22589449.
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  865. Di Angelantonio E, Gao P, Pennells L, Kaptoge S, Caslake M, Thompson A, Butterworth AS, Sarwar N, Wormser D, Saleheen D, Ballantyne CM, Psaty BM, Sundström J, Ridker PM, Nagel D, Gillum RF, Ford I, Ducimetiere P, Kiechl S, Koenig W, Dullaart RP, Assmann G, D'Agostino RB, Dagenais GR, Cooper JA, Kromhout D, Onat A, Tipping RW, Gómez-de-la-Cámara A, Rosengren A, Sutherland SE, Gallacher J, Fowkes FG, Casiglia E, Hofman A, Salomaa V, Barrett-Connor E, Clarke R, Brunner E, Jukema JW, Simons LA, Sandhu M, Wareham NJ, Khaw KT, Kauhanen J, Salonen JT, Howard WJ, Nordestgaard BG, Wood AM, Thompson SG, Boekholdt SM, Sattar N, Packard C, Gudnason V, Danesh J. Lipid-related markers and cardiovascular disease prediction. JAMA. 2012 Jun 20; 307(23):2499-506. PMID: 22797450; PMCID: PMC4211641.
  866. Nugteren JJ, Snijder CA, Hofman A, Jaddoe VW, Steegers EA, Burdorf A. Work-related maternal risk factors and the risk of pregnancy induced hypertension and preeclampsia during pregnancy. The Generation R Study. PLoS One. 2012; 7(6):e39263. PMID: 22720087; PMCID: PMC3376127.
  867. Durik M, Kavousi M, van der Pluijm I, Isaacs A, Cheng C, Verdonk K, Loot AE, Oeseburg H, Bhaggoe UM, Leijten F, van Veghel R, de Vries R, Rudez G, Brandt R, Ridwan YR, van Deel ED, de Boer M, Tempel D, Fleming I, Mitchell GF, Verwoert GC, Tarasov KV, Uitterlinden AG, Hofman A, Duckers HJ, van Duijn CM, Oostra BA, Witteman JC, Duncker DJ, Danser AH, Hoeijmakers JH, Roks AJ. Nucleotide excision DNA repair is associated with age-related vascular dysfunction. Circulation. 2012 Jul 24; 126(4):468-78. PMID: 22705887; PMCID: PMC3430727.
  868. Brautbar A, Pompeii LA, Dehghan A, Ngwa JS, Nambi V, Virani SS, Rivadeneira F, Uitterlinden AG, Hofman A, Witteman JC, Pencina MJ, Folsom AR, Cupples LA, Ballantyne CM, Boerwinkle E. A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies. Atherosclerosis. 2012 Aug; 223(2):421-6. PMID: 22789513; PMCID: PMC3595115.
  869. Freilinger T, Anttila V, de Vries B, Malik R, Kallela M, Terwindt GM, Pozo-Rosich P, Winsvold B, Nyholt DR, van Oosterhout WP, Artto V, Todt U, Hämäläinen E, Fernández-Morales J, Louter MA, Kaunisto MA, Schoenen J, Raitakari O, Lehtimäki T, Vila-Pueyo M, Göbel H, Wichmann E, Sintas C, Uitterlinden AG, Hofman A, Rivadeneira F, Heinze A, Tronvik E, van Duijn CM, Kaprio J, Cormand B, Wessman M, Frants RR, Meitinger T, Müller-Myhsok B, Zwart JA, Färkkilä M, Macaya A, Ferrari MD, Kubisch C, Palotie A, Dichgans M, van den Maagdenberg AM. Genome-wide association analysis identifies susceptibility loci for migraine without aura. Nat Genet. 2012 Jun 10; 44(7):777-82. PMID: 22683712; PMCID: PMC3773912.
  870. Verhoeven VJ, Hysi PG, Saw SM, Vitart V, Mirshahi A, Guggenheim JA, Cotch MF, Yamashiro K, Baird PN, Mackey DA, Wojciechowski R, Ikram MK, Hewitt AW, Duggal P, Janmahasatian S, Khor CC, Fan Q, Zhou X, Young TL, Tai ES, Goh LK, Li YJ, Aung T, Vithana E, Teo YY, Tay W, Sim X, Rudan I, Hayward C, Wright AF, Polasek O, Campbell H, Wilson JF, Fleck BW, Nakata I, Yoshimura N, Yamada R, Matsuda F, Ohno-Matsui K, Nag A, McMahon G, St Pourcain B, Lu Y, Rahi JS, Cumberland PM, Bhattacharya S, Simpson CL, Atwood LD, Li X, Raffel LJ, Murgia F, Portas L, Despriet DD, van Koolwijk LM, Wolfram C, Lackner KJ, Tönjes A, Mägi R, Lehtimäki T, Kähönen M, Esko T, Metspalu A, Rantanen T, Pärssinen O, Klein BE, Meitinger T, Spector TD, Oostra BA, Smith AV, de Jong PT, Hofman A, Amin N, Karssen LC, Rivadeneira F, Vingerling JR, Eiríksdóttir G, Gudnason V, Döring A, Bettecken T, Uitterlinden AG, Williams C, Zeller T, Castagné R, Oexle K, van Duijn CM, Iyengar SK, Mitchell P, Wang JJ, Höhn R, Pfeiffer N, Bailey-Wilson JE, Stambolian D, Wong TY, Hammond CJ, Klaver CC. Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. Hum Genet. 2012 Sep; 131(9):1467-80. PMID: 22665138; PMCID: PMC3418496.
  871. Tharner A, Luijk MP, Raat H, Ijzendoorn MH, Bakermans-Kranenburg MJ, Moll HA, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. Breastfeeding and its relation to maternal sensitivity and infant attachment. J Dev Behav Pediatr. 2012 Jun; 33(5):396-404. PMID: 22580735.
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  872. Coolman M, Timmermans S, de Groot CJ, Russcher H, Lindemans J, Hofman A, Geurts-Moespot AJ, Sweep FC, Jaddoe VV, Steegers EA. Angiogenic and fibrinolytic factors in blood during the first half of pregnancy and adverse pregnancy outcomes. Obstet Gynecol. 2012 Jun; 119(6):1190-200. PMID: 22617584.
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  873. Rurangirwa AA, Gaillard R, Steegers EA, Hofman A, Jaddoe VW. Hemodynamic adaptations in different trimesters among nulliparous and multiparous pregnant women; the Generation R study. Am J Hypertens. 2012 Aug; 25(8):892-9. PMID: 22647784.
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  874. Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, Balkau B, Benediktsson R, Bergman RN, Boerwinkle E, Bonnycastle L, Burtt NP, Campbell H, Charpentier G, Collins FS, Gieger C, Green T, Hadjadj S, Hattersley AT, Herder C, Hofman A, Johnson AD, Kottgen A, Kraft P, Labrune Y, Langenberg C, Manning AK, Mohlke KL, Morris AP, Oostra B, Pankow J, Petersen AK, Pramstaller PP, Prokopenko I, Rathmann W, Rayner W, Roden M, Rudan I, Rybin D, Scott LJ, Sigurdsson G, Sladek R, Thorleifsson G, Thorsteinsdottir U, Tuomilehto J, Uitterlinden AG, Vivequin S, Weedon MN, Wright AF, Hu FB, Illig T, Kao L, Meigs JB, Wilson JF, Stefansson K, van Duijn C, Altschuler D, Morris AD, Boehnke M, McCarthy MI, Froguel P, Palmer CN, Wareham NJ, Groop L, Frayling TM, Cauchi S. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet. 2012 May; 8(5):e1002741. PMID: 22693455; PMCID: PMC3364960.
  875. Rodenburg EM, Eijgelsheim M, Geleijnse JM, Amin N, van Duijn CM, Hofman A, Uitterlinden AG, Stricker BH, Visser LE. CYP1A2 and coffee intake and the modifying effect of sex, age, and smoking. Am J Clin Nutr. 2012 Jul; 96(1):182-7. PMID: 22648710.
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  876. Silva LM, van Rossem L, Jansen PW, Hokken-Koelega AC, Moll HA, Hofman A, Mackenbach JP, Jaddoe VW, Raat H. Children of low socioeconomic status show accelerated linear growth in early childhood; results from the Generation R Study. PLoS One. 2012; 7(5):e37356. PMID: 22649522; PMCID: PMC3359354.
  877. Kok R, Bakermans-Kranenburg MJ, van Ijzendoorn MH, Velders FP, Linting M, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. The role of maternal stress during pregnancy, maternal discipline, and child COMT Val158Met genotype in the development of compliance. Dev Psychobiol. 2013 Jul; 55(5):451-64. PMID: 22614783.
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  878. Bouthoorn SH, Gaillard R, Steegers EA, Hofman A, Jaddoe VW, van Lenthe FJ, Raat H. Ethnic differences in blood pressure and hypertensive complications during pregnancy: the Generation R study. Hypertension. 2012 Jul; 60(1):198-205. PMID: 22615112.
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  879. van Woudenbergh GJ, Kuijsten A, Tigcheler B, Sijbrands EJ, van Rooij FJ, Hofman A, Witteman JC, Feskens EJ. Meat consumption and its association with C-reactive protein and incident type 2 diabetes: the Rotterdam Study. Diabetes Care. 2012 Jul; 35(7):1499-505. PMID: 22596177; PMCID: PMC3379589.
  880. Verhaaren BF, Vernooij MW, Koudstaal PJ, Uitterlinden AG, van Duijn CM, Hofman A, Breteler MM, Ikram MA. Alzheimer's disease genes and cognition in the nondemented general population. Biol Psychiatry. 2013 Mar 01; 73(5):429-34. PMID: 22592056.
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  881. Manning AK, Hivert MF, Scott RA, Grimsby JL, Bouatia-Naji N, Chen H, Rybin D, Liu CT, Bielak LF, Prokopenko I, Amin N, Barnes D, Cadby G, Hottenga JJ, Ingelsson E, Jackson AU, Johnson T, Kanoni S, Ladenvall C, Lagou V, Lahti J, Lecoeur C, Liu Y, Martinez-Larrad MT, Montasser ME, Navarro P, Perry JR, Rasmussen-Torvik LJ, Salo P, Sattar N, Shungin D, Strawbridge RJ, Tanaka T, van Duijn CM, An P, de Andrade M, Andrews JS, Aspelund T, Atalay M, Aulchenko Y, Balkau B, Bandinelli S, Beckmann JS, Beilby JP, Bellis C, Bergman RN, Blangero J, Boban M, Boehnke M, Boerwinkle E, Bonnycastle LL, Boomsma DI, Borecki IB, Böttcher Y, Bouchard C, Brunner E, Budimir D, Campbell H, Carlson O, Chines PS, Clarke R, Collins FS, Corbatón-Anchuelo A, Couper D, de Faire U, Dedoussis GV, Deloukas P, Dimitriou M, Egan JM, Eiriksdottir G, Erdos MR, Eriksson JG, Eury E, Ferrucci L, Ford I, Forouhi NG, Fox CS, Franzosi MG, Franks PW, Frayling TM, Froguel P, Galan P, de Geus E, Gigante B, Glazer NL, Goel A, Groop L, Gudnason V, Hallmans G, Hamsten A, Hansson O, Harris TB, Hayward C, Heath S, Hercberg S, Hicks AA, Hingorani A, Hofman A, Hui J, Hung J, Jarvelin MR, Jhun MA, Johnson PC, Jukema JW, Jula A, Kao WH, Kaprio J, Kardia SL, Keinanen-Kiukaanniemi S, Kivimaki M, Kolcic I, Kovacs P, Kumari M, Kuusisto J, Kyvik KO, Laakso M, Lakka T, Lannfelt L, Lathrop GM, Launer LJ, Leander K, Li G, Lind L, Lindstrom J, Lobbens S, Loos RJ, Luan J, Lyssenko V, Mägi R, Magnusson PK, Marmot M, Meneton P, Mohlke KL, Mooser V, Morken MA, Miljkovic I, Narisu N, O'Connell J, Ong KK, Oostra BA, Palmer LJ, Palotie A, Pankow JS, Peden JF, Pedersen NL, Pehlic M, Peltonen L, Penninx B, Pericic M, Perola M, Perusse L, Peyser PA, Polasek O, Pramstaller PP, Province MA, Räikkönen K, Rauramaa R, Rehnberg E, Rice K, Rotter JI, Rudan I, Ruokonen A, Saaristo T, Sabater-Lleal M, Salomaa V, Savage DB, Saxena R, Schwarz P, Seedorf U, Sennblad B, Serrano-Rios M, Shuldiner AR, Sijbrands EJ, Siscovick DS, Smit JH, Small KS, Smith NL, Smith AV, Stancáková A, Stirrups K, Stumvoll M, Sun YV, Swift AJ, Tönjes A, Tuomilehto J, Trompet S, Uitterlinden AG, Uusitupa M, Vikström M, Vitart V, Vohl MC, Voight BF, Vollenweider P, Waeber G, Waterworth DM, Watkins H, Wheeler E, Widen E, Wild SH, Willems SM, Willemsen G, Wilson JF, Witteman JC, Wright AF, Yaghootkar H, Zelenika D, Zemunik T, Zgaga L, Wareham NJ, McCarthy MI, Barroso I, Watanabe RM, Florez JC, Dupuis J, Meigs JB, Langenberg C. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet. 2012 May 13; 44(6):659-69. PMID: 22581228; PMCID: PMC3613127.
  882. Flink IJ, Beirens TM, Looman C, Landgraf JM, Tiemeier H, Mol HA, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. Health-related quality of life of infants from ethnic minority groups: the Generation R Study. Qual Life Res. 2013 Apr; 22(3):653-64. PMID: 22572975; PMCID: PMC3607719.
  883. Steenweg-de Graaff J, Roza SJ, Steegers EA, Hofman A, Verhulst FC, Jaddoe VW, Tiemeier H. Maternal folate status in early pregnancy and child emotional and behavioral problems: the Generation R Study. Am J Clin Nutr. 2012 Jun; 95(6):1413-21. PMID: 22572645.
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  884. Bos D, van der Rijk MJ, Geeraedts TE, Hofman A, Krestin GP, Witteman JC, van der Lugt A, Ikram MA, Vernooij MW. Intracranial carotid artery atherosclerosis: prevalence and risk factors in the general population. Stroke. 2012 Jul; 43(7):1878-84. PMID: 22569939.
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  885. Castaño Betancourt MC, Cailotto F, Kerkhof HJ, Cornelis FM, Doherty SA, Hart DJ, Hofman A, Luyten FP, Maciewicz RA, Mangino M, Metrustry S, Muir K, Peters MJ, Rivadeneira F, Wheeler M, Zhang W, Arden N, Spector TD, Uitterlinden AG, Doherty M, Lories RJ, Valdes AM, van Meurs JB. Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):8218-23. PMID: 22566624; PMCID: PMC3361426.
  886. Hoeven TA, Kavousi M, Clockaerts S, Kerkhof HJ, van Meurs JB, Franco O, Hofman A, Bindels P, Witteman J, Bierma-Zeinstra S. Association of atherosclerosis with presence and progression of osteoarthritis: the Rotterdam Study. Ann Rheum Dis. 2013 May; 72(5):646-51. PMID: 22563029.
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  887. van Koolwijk LM, Ramdas WD, Ikram MK, Jansonius NM, Pasutto F, Hysi PG, Macgregor S, Janssen SF, Hewitt AW, Viswanathan AC, ten Brink JB, Hosseini SM, Amin N, Despriet DD, Willemse-Assink JJ, Kramer R, Rivadeneira F, Struchalin M, Aulchenko YS, Weisschuh N, Zenkel M, Mardin CY, Gramer E, Welge-Lüssen U, Montgomery GW, Carbonaro F, Young TL, Bellenguez C, McGuffin P, Foster PJ, Topouzis F, Mitchell P, Wang JJ, Wong TY, Czudowska MA, Hofman A, Uitterlinden AG, Wolfs RC, de Jong PT, Oostra BA, Paterson AD, Mackey DA, Bergen AA, Reis A, Hammond CJ, Vingerling JR, Lemij HG, Klaver CC, van Duijn CM. Common genetic determinants of intraocular pressure and primary open-angle glaucoma. PLoS Genet. 2012; 8(5):e1002611. PMID: 22570627.
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  888. Engberink MF, Bakker SJ, Brink EJ, van Baak MA, van Rooij FJ, Hofman A, Witteman JC, Geleijnse JM. Dietary acid load and risk of hypertension: the Rotterdam Study. Am J Clin Nutr. 2012 Jun; 95(6):1438-44. PMID: 22552032.
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  889. El Marroun H, Zeegers M, Steegers EA, van der Ende J, Schenk JJ, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Post-term birth and the risk of behavioural and emotional problems in early childhood. Int J Epidemiol. 2012 Jun; 41(3):773-81. PMID: 22552873.
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  890. Bradfield JP, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, Hypponen E, Holst C, Valcarcel B, Thiering E, Salem RM, Schumacher FR, Cousminer DL, Sleiman PM, Zhao J, Berkowitz RI, Vimaleswaran KS, Jarick I, Pennell CE, Evans DM, St Pourcain B, Berry DJ, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, van Duijn CM, van der Valk RJ, de Jongste JC, Postma DS, Boomsma DI, Gauderman WJ, Hassanein MT, Lindgren CM, Mägi R, Boreham CA, Neville CE, Moreno LA, Elliott P, Pouta A, Hartikainen AL, Li M, Raitakari O, Lehtimäki T, Eriksson JG, Palotie A, Dallongeville J, Das S, Deloukas P, McMahon G, Ring SM, Kemp JP, Buxton JL, Blakemore AI, Bustamante M, Guxens M, Hirschhorn JN, Gillman MW, Kreiner-Møller E, Bisgaard H, Gilliland FD, Heinrich J, Wheeler E, Barroso I, O'Rahilly S, Meirhaeghe A, Sørensen TI, Power C, Palmer LJ, Hinney A, Widen E, Farooqi IS, McCarthy MI, Froguel P, Meyre D, Hebebrand J, Jarvelin MR, Jaddoe VW, Smith GD, Hakonarson H, Grant SF. A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet. 2012 May; 44(5):526-31. PMID: 22484627; PMCID: PMC3370100.
  891. Ellinor PT, Lunetta KL, Albert CM, Glazer NL, Ritchie MD, Smith AV, Arking DE, Müller-Nurasyid M, Krijthe BP, Lubitz SA, Bis JC, Chung MK, Dörr M, Ozaki K, Roberts JD, Smith JG, Pfeufer A, Sinner MF, Lohman K, Ding J, Smith NL, Smith JD, Rienstra M, Rice KM, Van Wagoner DR, Magnani JW, Wakili R, Clauss S, Rotter JI, Steinbeck G, Launer LJ, Davies RW, Borkovich M, Harris TB, Lin H, Völker U, Völzke H, Milan DJ, Hofman A, Boerwinkle E, Chen LY, Soliman EZ, Voight BF, Li G, Chakravarti A, Kubo M, Tedrow UB, Rose LM, Ridker PM, Conen D, Tsunoda T, Furukawa T, Sotoodehnia N, Xu S, Kamatani N, Levy D, Nakamura Y, Parvez B, Mahida S, Furie KL, Rosand J, Muhammad R, Psaty BM, Meitinger T, Perz S, Wichmann HE, Witteman JC, Kao WH, Kathiresan S, Roden DM, Uitterlinden AG, Rivadeneira F, McKnight B, Sjögren M, Newman AB, Liu Y, Gollob MH, Melander O, Tanaka T, Stricker BH, Felix SB, Alonso A, Darbar D, Barnard J, Chasman DI, Heckbert SR, Benjamin EJ, Gudnason V, Kääb S. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet. 2012 Apr 29; 44(6):670-5. PMID: 22544366; PMCID: PMC3366038.
  892. Bos D, Vernooij MW, Elias-Smale SE, Verhaaren BF, Vrooman HA, Hofman A, Niessen WJ, Witteman JC, van der Lugt A, Ikram MA. Atherosclerotic calcification relates to cognitive function and to brain changes on magnetic resonance imaging. Alzheimers Dement. 2012 Oct; 8(5 Suppl):S104-11. PMID: 22537801.
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  893. Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S, Ropele S, Taal HR, Mook-Kanamori DO, Coker LH, Longstreth WT, Niessen WJ, DeStefano AL, Beiser A, Zijdenbos AP, Struchalin M, Jack CR, Rivadeneira F, Uitterlinden AG, Knopman DS, Hartikainen AL, Pennell CE, Thiering E, Steegers EA, Hakonarson H, Heinrich J, Palmer LJ, Jarvelin MR, McCarthy MI, Grant SF, St Pourcain B, Timpson NJ, Smith GD, Sovio U, Nalls MA, Au R, Hofman A, Gudnason H, van der Lugt A, Harris TB, Meeks WM, Vernooij MW, van Buchem MA, Catellier D, Jaddoe VW, Gudnason V, Windham BG, Wolf PA, van Duijn CM, Mosley TH, Schmidt H, Launer LJ, Breteler MM, DeCarli C. Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet. 2012 Apr 15; 44(5):539-44. PMID: 22504418; PMCID: PMC3618290.
  894. Taal HR, Pourcain BS, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Møller E, Bradfield JP, Freathy RM, Geller F, Guxens M, Cousminer DL, Kerkhof M, Timpson NJ, Ikram MA, Beilin LJ, Bønnelykke K, Buxton JL, Charoen P, Chawes BLK, Eriksson J, Evans DM, Hofman A, Kemp JP, Kim CE, Klopp N, Lahti J, Lye SJ, McMahon G, Mentch FD, Müller M, O'Reilly PF, Prokopenko I, Rivadeneira F, Steegers EAP, Sunyer J, Tiesler C, Yaghootkar H, Breteler MMB, Debette S, Fornage M, Gudnason V, Launer LJ, van der Lugt A, Mosley TH, Seshadri S, Smith AV, Vernooij MW, Blakemore AI, Chiavacci RM, Feenstra B, Fernandez-Benet J, Grant SFA, Hartikainen AL, van der Heijden AJ, Iñiguez C, Lathrop M, McArdle WL, Mølgaard A, Newnham JP, Palmer LJ, Palotie A, Pouta A, Ring SM, Sovio U, Standl M, Uitterlinden AG, Wichmann HE, Vissing NH, DeCarli C, van Duijn CM, McCarthy MI, Koppelman GH, Estivill X, Hattersley AT, Melbye M, Bisgaard H, Pennell CE, Widen E, Hakonarson H, Smith GD, Heinrich J, Jarvelin MR, Jaddoe VWV. Common variants at 12q15 and 12q24 are associated with infant head circumference. Nat Genet. 2012 Apr 15; 44(5):532-538. PMID: 22504419; PMCID: PMC3773913.
  895. Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, Garcia-Giralt N, Giroux S, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Khusainova R, Kim GS, Kooperberg C, Koromila T, Kruk M, Laaksonen M, Lacroix AZ, Lee SH, Leung PC, Lewis JR, Masi L, Mencej-Bedrac S, Nguyen TV, Nogues X, Patel MS, Prezelj J, Rose LM, Scollen S, Siggeirsdottir K, Smith AV, Svensson O, Trompet S, Trummer O, van Schoor NM, Woo J, Zhu K, Balcells S, Brandi ML, Buckley BM, Cheng S, Christiansen C, Cooper C, Dedoussis G, Ford I, Frost M, Goltzman D, González-Macías J, Kähönen M, Karlsson M, Khusnutdinova E, Koh JM, Kollia P, Langdahl BL, Leslie WD, Lips P, Ljunggren Ö, Lorenc RS, Marc J, Mellström D, Obermayer-Pietsch B, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Ridker PM, Rousseau F, Slagboom PE, Tang NL, Urreizti R, Van Hul W, Viikari J, Zarrabeitia MT, Aulchenko YS, Castano-Betancourt M, Grundberg E, Herrera L, Ingvarsson T, Johannsdottir H, Kwan T, Li R, Luben R, Medina-Gómez C, Palsson ST, Reppe S, Rotter JI, Sigurdsson G, van Meurs JB, Verlaan D, Williams FM, Wood AR, Zhou Y, Gautvik KM, Pastinen T, Raychaudhuri S, Cauley JA, Chasman DI, Clark GR, Cummings SR, Danoy P, Dennison EM, Eastell R, Eisman JA, Gudnason V, Hofman A, Jackson RD, Jones G, Jukema JW, Khaw KT, Lehtimäki T, Liu Y, Lorentzon M, McCloskey E, Mitchell BD, Nandakumar K, Nicholson GC, Oostra BA, Peacock M, Pols HA, Prince RL, Raitakari O, Reid IR, Robbins J, Sambrook PN, Sham PC, Shuldiner AR, Tylavsky FA, van Duijn CM, Wareham NJ, Cupples LA, Econs MJ, Evans DM, Harris TB, Kung AW, Psaty BM, Reeve J, Spector TD, Streeten EA, Zillikens MC, Thorsteinsdottir U, Ohlsson C, Karasik D, Richards JB, Brown MA, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet. 2012 Apr 15; 44(5):491-501. PMID: 22504420; PMCID: PMC3338864.
  896. Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15; 44(5):545-51. PMID: 22504421; PMCID: PMC3427729.
  897. Fedorowski A, Franceschini N, Brody J, Liu C, Verwoert GC, Boerwinkle E, Couper D, Rice KM, Rotter JI, Mattace-Raso F, Uitterlinden A, Hofman A, Almgren P, Sjögren M, Hedblad B, Larson MG, Newton-Cheh C, Wang TJ, Rose KM, Psaty BM, Levy D, Witteman J, Melander O. Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium. Eur Heart J. 2012 Sep; 33(18):2331-41. PMID: 22504314; PMCID: PMC3442958.
  898. Diekstra FP, Saris CG, van Rheenen W, Franke L, Jansen RC, van Es MA, van Vught PW, Blauw HM, Groen EJ, Horvath S, Estrada K, Rivadeneira F, Hofman A, Uitterlinden AG, Robberecht W, Andersen PM, Melki J, Meininger V, Hardiman O, Landers JE, Brown RH, Shatunov A, Shaw CE, Leigh PN, Al-Chalabi A, Ophoff RA, van den Berg LH, Veldink JH. Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS. PLoS One. 2012; 7(4):e35333. PMID: 22509407; PMCID: PMC3324559.
  899. Mühleisen TW, Mattheisen M, Strohmaier J, Degenhardt F, Priebe L, Schultz CC, Breuer R, Meier S, Hoffmann P, Rivandeneira F, Hofman A, Uitterlinden AG, Moebus S, Gieger C, Emeny R, Ladwig KH, Wichmann HE, Schwarz M, Kammerer-Ciernioch J, Schlösser RG, Nenadic I, Sauer H, Mössner R, Maier W, Rujescu D, Lange C, Ophoff RA, Schulze TG, Rietschel M, Nöthen MM, Cichon S. Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder. Schizophr Res. 2012 Jun; 138(1):69-73. PMID: 22497794.
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  900. van Rossem L, Kiefte-de Jong JC, Looman CW, Jaddoe VW, Hofman A, Hokken-Koelega AC, Mackenbach JP, Moll HA, Raat H. Weight change before and after the introduction of solids: results from a longitudinal birth cohort. Br J Nutr. 2013 Jan 28; 109(2):370-5. PMID: 22475475.
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  901. Kiefte-de Jong JC, de Vries JH, Bleeker SE, Jaddoe VW, Hofman A, Raat H, Moll HA. Socio-demographic and lifestyle determinants of 'Western-like' and 'Health conscious' dietary patterns in toddlers. Br J Nutr. 2013 Jan 14; 109(1):137-47. PMID: 22475342.
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  902. Gabriele C, Silva LM, Arends LR, Raat H, Moll HA, Hofman A, Jaddoe VW, de Jongste JC. Early respiratory morbidity in a multicultural birth cohort: the Generation R Study. Eur J Epidemiol. 2012 Jun; 27(6):453-62. PMID: 22476729; PMCID: PMC3382637.
  903. Leermakers ET, Taal HR, Bakker R, Steegers EA, Hofman A, Jaddoe VW. A common genetic variant at 15q25 modifies the associations of maternal smoking during pregnancy with fetal growth: the generation R study. PLoS One. 2012; 7(4):e34584. PMID: 22496830; PMCID: PMC3319619.
  904. van Kempen BJ, Ferket BS, Hofman A, Spronk S, Steyerberg E, Hunink MG. Do different methods of modeling statin treatment effectiveness influence the optimal decision? Med Decis Making. 2012 May-Jun; 32(3):507-16. PMID: 22472915.
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  905. Ramdas WD, Wolfs RC, Kiefte-de Jong JC, Hofman A, de Jong PT, Vingerling JR, Jansonius NM. Nutrient intake and risk of open-angle glaucoma: the Rotterdam Study. Eur J Epidemiol. 2012 May; 27(5):385-93. PMID: 22461101; PMCID: PMC3374099.
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  908. Ray K, Wainwright NW, Visser L, Witteman J, Breteler M, Ambegaonkar B, Hofman A, Stricker B, Wareham N, Khaw KT, Sandhu M. Changes in HDL cholesterol and cardiovascular outcomes after lipid modification therapy. Heart. 2012 May; 98(10):780-5. PMID: 22447463; PMCID: PMC3773905.
  909. Taal HR, van den Hil LC, Hofman A, van der Heijden AJ, Jaddoe VW. Genetic variants associated with adult blood pressure and kidney function do not affect fetal kidney volume. The Generation R Study. Early Hum Dev. 2012 Sep; 88(9):711-6. PMID: 22445569.
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  910. Gasten AC, Ramdas WD, Broer L, van Koolwijk LM, Ikram MK, de Jong PT, Aulchenko YS, Wolfs RC, Hofman A, Rivadeneira F, Uitterlinden AG, Oostra BA, Lemij HG, Klaver CC, Jansonius NM, Vingerling JR, van Duijn CM. A genetic epidemiologic study of candidate genes involved in the optic nerve head morphology. Invest Ophthalmol Vis Sci. 2012 Mar 21; 53(3):1485-91. PMID: 22266513.
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  911. He C, Chasman DI, Dreyfus J, Hwang SJ, Ruiter R, Sanna S, Buring JE, Fernández-Rhodes L, Franceschini N, Hankinson SE, Hofman A, Lunetta KL, Palmieri G, Porcu E, Rivadeneira F, Rose LM, Splansky GL, Stolk L, Uitterlinden AG, Chanock SJ, Crisponi L, Demerath EW, Murabito JM, Ridker PM, Stricker BH, Hunter DJ. Reproductive aging-associated common genetic variants and the risk of breast cancer. Breast Cancer Res. 2012 Mar 20; 14(2):R54. PMID: 22433456; PMCID: PMC3446388.
  912. Kavousi M, Elias-Smale S, Rutten JH, Leening MJ, Vliegenthart R, Verwoert GC, Krestin GP, Oudkerk M, de Maat MP, Leebeek FW, Mattace-Raso FU, Lindemans J, Hofman A, Steyerberg EW, van der Lugt A, van den Meiracker AH, Witteman JC. Evaluation of newer risk markers for coronary heart disease risk classification: a cohort study. Ann Intern Med. 2012 Mar 20; 156(6):438-44. PMID: 22431676.
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  913. Baas DC, Ho L, Tanck MW, Fritsche LG, Merriam JE, van het Slot R, Koeleman BP, Gorgels TG, van Duijn CM, Uitterlinden AG, de Jong PT, Hofman A, ten Brink JB, Vingerling JR, Klaver CC, Dean M, Weber BH, Allikmets R, Hageman GS, Bergen AA. Multicenter cohort association study of SLC2A1 single nucleotide polymorphisms and age-related macular degeneration. Mol Vis. 2012; 18:657-74. PMID: 22509097; PMCID: PMC3324365.
  914. Wieberdink RG, Ikram MA, Hofman A, Koudstaal PJ, Breteler MM. Trends in stroke incidence rates and stroke risk factors in Rotterdam, the Netherlands from 1990 to 2008. Eur J Epidemiol. 2012 Apr; 27(4):287-95. PMID: 22426770; PMCID: PMC3370158.
  915. Sarwar N, Butterworth AS, Freitag DF, Gregson J, Willeit P, Gorman DN, Gao P, Saleheen D, Rendon A, Nelson CP, Braund PS, Hall AS, Chasman DI, Tybjærg-Hansen A, Chambers JC, Benjamin EJ, Franks PW, Clarke R, Wilde AA, Trip MD, Steri M, Witteman JC, Qi L, van der Schoot CE, de Faire U, Erdmann J, Stringham HM, Koenig W, Rader DJ, Melzer D, Reich D, Psaty BM, Kleber ME, Panagiotakos DB, Willeit J, Wennberg P, Woodward M, Adamovic S, Rimm EB, Meade TW, Gillum RF, Shaffer JA, Hofman A, Onat A, Sundström J, Wassertheil-Smoller S, Mellström D, Gallacher J, Cushman M, Tracy RP, Kauhanen J, Karlsson M, Salonen JT, Wilhelmsen L, Amouyel P, Cantin B, Best LG, Ben-Shlomo Y, Manson JE, Davey-Smith G, de Bakker PI, O'Donnell CJ, Wilson JF, Wilson AG, Assimes TL, Jansson JO, Ohlsson C, Tivesten Å, Ljunggren Ö, Reilly MP, Hamsten A, Ingelsson E, Cambien F, Hung J, Thomas GN, Boehnke M, Schunkert H, Asselbergs FW, Kastelein JJ, Gudnason V, Salomaa V, Harris TB, Kooner JS, Allin KH, Nordestgaard BG, Hopewell JC, Goodall AH, Ridker PM, Hólm H, Watkins H, Ouwehand WH, Samani NJ, Kaptoge S, Di Angelantonio E, Harari O, Danesh J. Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet. 2012 Mar 31; 379(9822):1205-13. PMID: 22421339; PMCID: PMC3316940.
  916. Hoogendam YY, van der Geest JN, van der Lijn F, van der Lugt A, Niessen WJ, Krestin GP, Hofman A, Vernooij MW, Breteler MM, Ikram MA. Determinants of cerebellar and cerebral volume in the general elderly population. Neurobiol Aging. 2012 Dec; 33(12):2774-81. PMID: 22405042.
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  917. Kiefte-de Jong JC, Timmermans S, Jaddoe VW, Hofman A, Tiemeier H, Steegers EA, de Jongste JC, Moll HA. High circulating folate and vitamin B-12 concentrations in women during pregnancy are associated with increased prevalence of atopic dermatitis in their offspring. J Nutr. 2012 Apr; 142(4):731-8. PMID: 22399526.
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  918. Leening MJ, Kavousi M, Heeringa J, van Rooij FJ, Verkroost-van Heemst J, Deckers JW, Mattace-Raso FU, Ziere G, Hofman A, Stricker BH, Witteman JC. Methods of data collection and definitions of cardiac outcomes in the Rotterdam Study. Eur J Epidemiol. 2012 Mar; 27(3):173-85. PMID: 22388767; PMCID: PMC3319884.
  919. Direk N, Koudstaal PJ, Hofman A, Ikram MA, Hoogendijk WJ, Tiemeier H. Cerebral hemodynamics and incident depression: the Rotterdam Study. Biol Psychiatry. 2012 Aug 15; 72(4):318-23. PMID: 22381733.
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  920. Tromp II, Kiefte-de Jong JC, de Vries JH, Jaddoe VW, Raat H, Hofman A, de Jongste JC, Moll HA. Dietary patterns and respiratory symptoms in pre-school children: the Generation R Study. Eur Respir J. 2012 Sep; 40(3):681-9. PMID: 22362860.
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  921. Van den Hooven EH, Pierik FH, Van Ratingen SW, Zandveld PY, Meijer EW, Hofman A, Miedema HM, Jaddoe VW, De Kluizenaar Y. Air pollution exposure estimation using dispersion modelling and continuous monitoring data in a prospective birth cohort study in The Netherlands. Environ Health. 2012 Feb 22; 11:9. PMID: 22356901; PMCID: PMC3372438.
  922. Timmermans S, Steegers-Theunissen RP, Vujkovic M, den Breeijen H, Russcher H, Lindemans J, Mackenbach J, Hofman A, Lesaffre EE, Jaddoe VV, Steegers EA. The Mediterranean diet and fetal size parameters: the Generation R Study. Br J Nutr. 2012 Oct 28; 108(8):1399-409. PMID: 22348517.
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  923. Walter S, Mackenbach J, Vokó Z, Lhachimi S, Ikram MA, Uitterlinden AG, Newman AB, Murabito JM, Garcia ME, Gudnason V, Tanaka T, Tranah GJ, Wallaschofski H, Kocher T, Launer LJ, Franceschini N, Schipper M, Hofman A, Tiemeier H. Genetic, physiological, and lifestyle predictors of mortality in the general population. Am J Public Health. 2012 Apr; 102(4):e3-10. PMID: 22397355; PMCID: PMC3489349.
  924. Demirkan A, van Duijn CM, Ugocsai P, Isaacs A, Pramstaller PP, Liebisch G, Wilson JF, Johansson Å, Rudan I, Aulchenko YS, Kirichenko AV, Janssens AC, Jansen RC, Gnewuch C, Domingues FS, Pattaro C, Wild SH, Jonasson I, Polasek O, Zorkoltseva IV, Hofman A, Karssen LC, Struchalin M, Floyd J, Igl W, Biloglav Z, Broer L, Pfeufer A, Pichler I, Campbell S, Zaboli G, Kolcic I, Rivadeneira F, Huffman J, Hastie ND, Uitterlinden A, Franke L, Franklin CS, Vitart V, Nelson CP, Preuss M, Bis JC, O'Donnell CJ, Franceschini N, Witteman JC, Axenovich T, Oostra BA, Meitinger T, Hicks AA, Hayward C, Wright AF, Gyllensten U, Campbell H, Schmitz G. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. PLoS Genet. 2012; 8(2):e1002490. PMID: 22359512; PMCID: PMC3280968.
  925. Alssema M, Newson RS, Bakker SJ, Stehouwer CD, Heymans MW, Nijpels G, Hillege HL, Hofman A, Witteman JC, Gansevoort RT, Dekker JM. One risk assessment tool for cardiovascular disease, type 2 diabetes, and chronic kidney disease. Diabetes Care. 2012 Apr; 35(4):741-8. PMID: 22338109; PMCID: PMC3308277.
  926. van den Hooven EH, de Kluizenaar Y, Pierik FH, Hofman A, van Ratingen SW, Zandveld PY, Lindemans J, Russcher H, Steegers EA, Miedema HM, Jaddoe VW. Chronic air pollution exposure during pregnancy and maternal and fetal C-reactive protein levels: the Generation R Study. Environ Health Perspect. 2012 May; 120(5):746-51. PMID: 22306530; PMCID: PMC3346784.
  927. Snijder CA, Kortenkamp A, Steegers EA, Jaddoe VW, Hofman A, Hass U, Burdorf A. Intrauterine exposure to mild analgesics during pregnancy and the occurrence of cryptorchidism and hypospadia in the offspring: the Generation R Study. Hum Reprod. 2012 Apr; 27(4):1191-201. PMID: 22301570.
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  928. Kiefte-de Jong JC, de Vries JH, Escher JC, Jaddoe VW, Hofman A, Raat H, Moll HA. Role of dietary patterns, sedentary behaviour and overweight on the longitudinal development of childhood constipation: the Generation R study. Matern Child Nutr. 2013 Oct; 9(4):511-23. PMID: 22288911.
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  929. Stolk L, Perry JR, Chasman DI, He C, Mangino M, Sulem P, Barbalic M, Broer L, Byrne EM, Ernst F, Esko T, Franceschini N, Gudbjartsson DF, Hottenga JJ, Kraft P, McArdle PF, Porcu E, Shin SY, Smith AV, van Wingerden S, Zhai G, Zhuang WV, Albrecht E, Alizadeh BZ, Aspelund T, Bandinelli S, Lauc LB, Beckmann JS, Boban M, Boerwinkle E, Broekmans FJ, Burri A, Campbell H, Chanock SJ, Chen C, Cornelis MC, Corre T, Coviello AD, d'Adamo P, Davies G, de Faire U, de Geus EJ, Deary IJ, Dedoussis GV, Deloukas P, Ebrahim S, Eiriksdottir G, Emilsson V, Eriksson JG, Fauser BC, Ferreli L, Ferrucci L, Fischer K, Folsom AR, Garcia ME, Gasparini P, Gieger C, Glazer N, Grobbee DE, Hall P, Haller T, Hankinson SE, Hass M, Hayward C, Heath AC, Hofman A, Ingelsson E, Janssens AC, Johnson AD, Karasik D, Kardia SL, Keyzer J, Kiel DP, Kolcic I, Kutalik Z, Lahti J, Lai S, Laisk T, Laven JS, Lawlor DA, Liu J, Lopez LM, Louwers YV, Magnusson PK, Marongiu M, Martin NG, Klaric IM, Masciullo C, McKnight B, Medland SE, Melzer D, Mooser V, Navarro P, Newman AB, Nyholt DR, Onland-Moret NC, Palotie A, Paré G, Parker AN, Pedersen NL, Peeters PH, Pistis G, Plump AS, Polasek O, Pop VJ, Psaty BM, Räikkönen K, Rehnberg E, Rotter JI, Rudan I, Sala C, Salumets A, Scuteri A, Singleton A, Smith JA, Snieder H, Soranzo N, Stacey SN, Starr JM, Stathopoulou MG, Stirrups K, Stolk RP, Styrkarsdottir U, Sun YV, Tenesa A, Thorand B, Toniolo D, Tryggvadottir L, Tsui K, Ulivi S, van Dam RM, van der Schouw YT, van Gils CH, van Nierop P, Vink JM, Visscher PM, Voorhuis M, Waeber G, Wallaschofski H, Wichmann HE, Widen E, Wijnands-van Gent CJ, Willemsen G, Wilson JF, Wolffenbuttel BH, Wright AF, Yerges-Armstrong LM, Zemunik T, Zgaga L, Zillikens MC, Zygmunt M, Arnold AM, Boomsma DI, Buring JE, Crisponi L, Demerath EW, Gudnason V, Harris TB, Hu FB, Hunter DJ, Launer LJ, Metspalu A, Montgomery GW, Oostra BA, Ridker PM, Sanna S, Schlessinger D, Spector TD, Stefansson K, Streeten EA, Thorsteinsdottir U, Uda M, Uitterlinden AG, van Duijn CM, Völzke H, Murray A, Murabito JM, Visser JA, Lunetta KL. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet. 2012 Jan 22; 44(3):260-8. PMID: 22267201; PMCID: PMC3288642.
  930. Sonnenschein-van der Voort AM, Jaddoe VW, Raat H, Moll HA, Hofman A, de Jongste JC, Duijts L. Fetal and infant growth and asthma symptoms in preschool children: the Generation R Study. Am J Respir Crit Care Med. 2012 Apr 01; 185(7):731-7. PMID: 22268138.
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  931. Wolff NJ, Darlington AS, Hunfeld JA, Jaddoe VW, Hofman A, Raat H, Verhulst FC, Passchier J, Tiemeier H. Concurrent and longitudinal bidirectional relationships between toddlers' chronic pain and mental health: the generation R study. J Pediatr Psychol. 2012 Jun; 37(5):546-56. PMID: 22262916.
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  932. Hafkamp-de Groen E, van Rossem L, de Jongste JC, Mohangoo AD, Moll HA, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. The role of prenatal, perinatal and postnatal factors in the explanation of socioeconomic inequalities in preschool asthma symptoms: the Generation R Study. J Epidemiol Community Health. 2012 Nov; 66(11):1017-24. PMID: 22268130.
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  933. Cents RA, Tiemeier H, Velders FP, Jaddoe VW, Hofman A, Verhulst FC, Lambregtse-van den Berg MP, Hudziak JJ. Maternal smoking during pregnancy and child emotional problems: the relevance of maternal and child 5-HTTLPR genotype. Am J Med Genet B Neuropsychiatr Genet. 2012 Apr; 159B(3):289-97. PMID: 22259195.
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  934. Ramdas WD, Wolfs RC, Hofman A, de Jong PT, Vingerling JR, Jansonius NM. Author response: incident open-angle glaucoma and ocular perfusion pressure. Invest Ophthalmol Vis Sci. 2012 Jan 17; 53(1):150-1. PMID: 22253362.
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  935. den Heijer T, van der Lijn F, Ikram A, Koudstaal PJ, van der Lugt A, Krestin GP, Vrooman HA, Hofman A, Niessen WJ, Breteler MM. Vascular risk factors, apolipoprotein E, and hippocampal decline on magnetic resonance imaging over a 10-year follow-up. Alzheimers Dement. 2012 Sep; 8(5):417-25. PMID: 22244650.
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  936. Heuvers ME, Aerts JG, Hegmans JP, Veltman JD, Uitterlinden AG, Ruiter R, Rodenburg EM, Hofman A, Bakker M, Hoogsteden HC, Stricker BH, van Klaveren RJ. History of tuberculosis as an independent prognostic factor for lung cancer survival. Lung Cancer. 2012 Jun; 76(3):452-6. PMID: 22226628.
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  955. Elens L, Becker ML, Haufroid V, Hofman A, Visser LE, Uitterlinden AG, Stricker BCh, van Schaik RH. Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study. Pharmacogenet Genomics. 2011 Dec; 21(12):861-6. PMID: 21946898.
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  956. Liu F, Struchalin MV, Duijn Kv, Hofman A, Uitterlinden AG, Duijn Cv, Aulchenko YS, Kayser M. Detecting low frequent loss-of-function alleles in genome wide association studies with red hair color as example. PLoS One. 2011; 6(11):e28145. PMID: 22140526; PMCID: PMC3226656.
  957. Broer L, Koudstaal PJ, Amin N, Rivadeneira F, Uitterlinden AG, Hofman A, Oostra BA, Breteler MM, Ikram MA, van Duijn CM. Association of heat shock proteins with Parkinson's disease. Eur J Epidemiol. 2011 Dec; 26(12):933-5. PMID: 22120601; PMCID: PMC3253286.
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  963. van Rossem L, Vogel I, Moll HA, Jaddoe VW, Hofman A, Mackenbach JP, Raat H. An observational study on socio-economic and ethnic differences in indicators of sedentary behavior and physical activity in preschool children. Prev Med. 2012 Jan; 54(1):55-60. PMID: 22064316.
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  964. Muller O, Mangiacapra F, Ntalianis A, Verhamme KM, Trana C, Hamilos M, Bartunek J, Vanderheyden M, Wyffels E, Heyndrickx GR, van Rooij FJ, Witteman JC, Hofman A, Wijns W, Barbato E, De Bruyne B. Long-term follow-up after fractional flow reserve-guided treatment strategy in patients with an isolated proximal left anterior descending coronary artery stenosis. JACC Cardiovasc Interv. 2011 Nov; 4(11):1175-82. PMID: 22035875.
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  965. Bakker R, Timmermans S, Steegers EA, Hofman A, Jaddoe VW. Folic acid supplements modify the adverse effects of maternal smoking on fetal growth and neonatal complications. J Nutr. 2011 Dec; 141(12):2172-9. PMID: 22031658.
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  992. Ramdas WD, Wolfs RC, Hofman A, de Jong PT, Vingerling JR, Jansonius NM. Ocular perfusion pressure and the incidence of glaucoma: real effect or artifact? The Rotterdam Study. Invest Ophthalmol Vis Sci. 2011 Aug 29; 52(9):6875-81. PMID: 21715354.
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  995. Verhaaren BF, de Boer R, Vernooij MW, Rivadeneira F, Uitterlinden AG, Hofman A, Krestin GP, van der Lugt A, Niessen WJ, Breteler MM, Ikram MA. Replication study of chr17q25 with cerebral white matter lesion volume. Stroke. 2011 Nov; 42(11):3297-9. PMID: 21868733.
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  996. Day-Williams AG, Southam L, Panoutsopoulou K, Rayner NW, Esko T, Estrada K, Helgadottir HT, Hofman A, Ingvarsson T, Jonsson H, Keis A, Kerkhof HJ, Thorleifsson G, Arden NK, Carr A, Chapman K, Deloukas P, Loughlin J, McCaskie A, Ollier WE, Ralston SH, Spector TD, Wallis GA, Wilkinson JM, Aslam N, Birell F, Carluke I, Joseph J, Rai A, Reed M, Walker K, Doherty SA, Jonsdottir I, Maciewicz RA, Muir KR, Metspalu A, Rivadeneira F, Stefansson K, Styrkarsdottir U, Uitterlinden AG, van Meurs JB, Zhang W, Valdes AM, Doherty M, Zeggini E. A variant in MCF2L is associated with osteoarthritis. Am J Hum Genet. 2011 Sep 09; 89(3):446-50. PMID: 21871595; PMCID: PMC3169824.
  997. Székely E, Herba CM, Arp PP, Uitterlinden AG, Jaddoe VW, Hofman A, Verhulst FC, Hudziak JJ, Tiemeier H. Recognition of scared faces and the serotonin transporter gene in young children: the Generation R Study. J Child Psychol Psychiatry. 2011 Dec; 52(12):1279-86. PMID: 21864315.
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  998. Bakker R, Steegers EA, Hofman A, Jaddoe VW. Blood pressure in different gestational trimesters, fetal growth, and the risk of adverse birth outcomes: the generation R study. Am J Epidemiol. 2011 Oct 01; 174(7):797-806. PMID: 21859836.
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  999. Kuningas M, Estrada K, Hsu YH, Nandakumar K, Uitterlinden AG, Lunetta KL, van Duijn CM, Karasik D, Hofman A, Murabito J, Rivadeneira F, Kiel DP, Tiemeier H. Large common deletions associate with mortality at old age. Hum Mol Genet. 2011 Nov 01; 20(21):4290-6. PMID: 21835882; PMCID: PMC3188993.
  1000. van den Bouwhuijsen QJ, Vernooij MW, Hofman A, Krestin GP, van der Lugt A, Witteman JC. Determinants of magnetic resonance imaging detected carotid plaque components: the Rotterdam Study. Eur Heart J. 2012 Jan; 33(2):221-9. PMID: 21821844.
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  1001. Gaillard R, Bakker R, Willemsen SP, Hofman A, Steegers EA, Jaddoe VW. Blood pressure tracking during pregnancy and the risk of gestational hypertensive disorders: the Generation R Study. Eur Heart J. 2011 Dec; 32(24):3088-97. PMID: 21821845.
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  1002. Hoorn EJ, Rivadeneira F, van Meurs JB, Ziere G, Stricker BH, Hofman A, Pols HA, Zietse R, Uitterlinden AG, Zillikens MC. Mild hyponatremia as a risk factor for fractures: the Rotterdam Study. J Bone Miner Res. 2011 Aug; 26(8):1822-8. PMID: 21381111.
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  1003. Mohangoo AD, de Koning HJ, de Jongste JC, Landgraf JM, van der Wouden JC, Jaddoe VW, Hofman A, Moll HA, Mackenbach JP, Raat H. Asthma-like symptoms in the first year of life and health-related quality of life at age 12 months: the Generation R study. Qual Life Res. 2012 Apr; 21(3):545-54. PMID: 21792733.
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  1004. Kuningas M, McQuillan R, Wilson JF, Hofman A, van Duijn CM, Uitterlinden AG, Tiemeier H. Runs of homozygosity do not influence survival to old age. PLoS One. 2011; 6(7):e22580. PMID: 21799906; PMCID: PMC3143169.
  1005. Walter S, Atzmon G, Demerath EW, Garcia ME, Kaplan RC, Kumari M, Lunetta KL, Milaneschi Y, Tanaka T, Tranah GJ, Völker U, Yu L, Arnold A, Benjamin EJ, Biffar R, Buchman AS, Boerwinkle E, Couper D, De Jager PL, Evans DA, Harris TB, Hoffmann W, Hofman A, Karasik D, Kiel DP, Kocher T, Kuningas M, Launer LJ, Lohman KK, Lutsey PL, Mackenbach J, Marciante K, Psaty BM, Reiman EM, Rotter JI, Seshadri S, Shardell MD, Smith AV, van Duijn C, Walston J, Zillikens MC, Bandinelli S, Baumeister SE, Bennett DA, Ferrucci L, Gudnason V, Kivimaki M, Liu Y, Murabito JM, Newman AB, Tiemeier H, Franceschini N. A genome-wide association study of aging. Neurobiol Aging. 2011 Nov; 32(11):2109.e15-28. PMID: 21782286; PMCID: PMC3193030.
  1006. Mook-Kanamori DO, Durmus B, Sovio U, Hofman A, Raat H, Steegers EA, Jarvelin MR, Jaddoe VW. Fetal and infant growth and the risk of obesity during early childhood: the Generation R Study. Eur J Endocrinol. 2011 Oct; 165(4):623-30. PMID: 21775498.
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  1007. Luijk MP, Roisman GI, Haltigan JD, Tiemeier H, Booth-Laforce C, van Ijzendoorn MH, Belsky J, Uitterlinden AG, Jaddoe VW, Hofman A, Verhulst FC, Tharner A, Bakermans-Kranenburg MJ. Dopaminergic, serotonergic, and oxytonergic candidate genes associated with infant attachment security and disorganization? In search of main and interaction effects. J Child Psychol Psychiatry. 2011 Dec; 52(12):1295-307. PMID: 21749372; PMCID: PMC3202071.
  1008. Tas U, Verhagen AP, Bierma-Zeinstra SM, Hofman A, Pols HA, Koes BW. Course and prognostic factors of disability in community-dwelling older people with mild disability: the Rotterdam Study. Australas J Ageing. 2012 Mar; 31(1):28-33. PMID: 22417151.
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  1009. van Loon JE, de Maat MP, Hofman A, Witteman JC, Leebeek FW. Relationship between thrombospondin gene variations, von Willebrand factor levels and the risk of coronary heart disease in an older population. J Thromb Haemost. 2011 Jul; 9(7):1415-7. PMID: 21518247.
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  1010. Arking DE, Junttila MJ, Goyette P, Huertas-Vazquez A, Eijgelsheim M, Blom MT, Newton-Cheh C, Reinier K, Teodorescu C, Uy-Evanado A, Carter-Monroe N, Kaikkonen KS, Kortelainen ML, Boucher G, Lagacé C, Moes A, Zhao X, Kolodgie F, Rivadeneira F, Hofman A, Witteman JC, Uitterlinden AG, Marsman RF, Pazoki R, Bardai A, Koster RW, Dehghan A, Hwang SJ, Bhatnagar P, Post W, Hilton G, Prineas RJ, Li M, Köttgen A, Ehret G, Boerwinkle E, Coresh J, Kao WH, Psaty BM, Tomaselli GF, Sotoodehnia N, Siscovick DS, Burke GL, Marbán E, Spooner PM, Cupples LA, Jui J, Gunson K, Kesäniemi YA, Wilde AA, Tardif JC, O'Donnell CJ, Bezzina CR, Virmani R, Stricker BH, Tan HL, Albert CM, Chakravarti A, Rioux JD, Huikuri HV, Chugh SS. Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals. PLoS Genet. 2011 Jun; 7(6):e1002158. PMID: 21738491; PMCID: PMC3128111.
  1011. Nalls MA, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Toniolo D, Zakai NA, Yang Q, Greinacher A, Wood AR, Garcia M, Gasparini P, Liu Y, Lumley T, Folsom AR, Reiner AP, Gieger C, Lagou V, Felix JF, Völzke H, Gouskova NA, Biffi A, Döring A, Völker U, Chong S, Wiggins KL, Rendon A, Dehghan A, Moore M, Taylor K, Wilson JG, Lettre G, Hofman A, Bis JC, Pirastu N, Fox CS, Meisinger C, Sambrook J, Arepalli S, Nauck M, Prokisch H, Stephens J, Glazer NL, Cupples LA, Okada Y, Takahashi A, Kamatani Y, Matsuda K, Tsunoda T, Tanaka T, Kubo M, Nakamura Y, Yamamoto K, Kamatani N, Stumvoll M, Tönjes A, Prokopenko I, Illig T, Patel KV, Garner SF, Kuhnel B, Mangino M, Oostra BA, Thein SL, Coresh J, Wichmann HE, Menzel S, Lin J, Pistis G, Uitterlinden AG, Spector TD, Teumer A, Eiriksdottir G, Gudnason V, Bandinelli S, Frayling TM, Chakravarti A, van Duijn CM, Melzer D, Ouwehand WH, Levy D, Boerwinkle E, Singleton AB, Hernandez DG, Longo DL, Soranzo N, Witteman JC, Psaty BM, Ferrucci L, Harris TB, O'Donnell CJ, Ganesh SK. Multiple loci are associated with white blood cell phenotypes. PLoS Genet. 2011 Jun; 7(6):e1002113. PMID: 21738480; PMCID: PMC3128114.
  1012. Luijk MP, Tharner A, Bakermans-Kranenburg MJ, van Ijzendoorn MH, Jaddoe VW, Hofman A, Verhulst FC, Tiemeier H. The association between parenting and attachment security is moderated by a polymorphism in the mineralocorticoid receptor gene: evidence for differential susceptibility. Biol Psychol. 2011 Sep; 88(1):37-40. PMID: 21718752.
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  1013. Kilpeläinen TO, Zillikens MC, Stancákova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS, Luan J, Vandenput L, Styrkarsdottir U, Zhou Y, Smith AV, Zhao JH, Amin N, Vedantam S, Shin SY, Haritunians T, Fu M, Feitosa MF, Kumari M, Halldorsson BV, Tikkanen E, Mangino M, Hayward C, Song C, Arnold AM, Aulchenko YS, Oostra BA, Campbell H, Cupples LA, Davis KE, Döring A, Eiriksdottir G, Estrada K, Fernández-Real JM, Garcia M, Gieger C, Glazer NL, Guiducci C, Hofman A, Humphries SE, Isomaa B, Jacobs LC, Jula A, Karasik D, Karlsson MK, Khaw KT, Kim LJ, Kivimäki M, Klopp N, Kühnel B, Kuusisto J, Liu Y, Ljunggren O, Lorentzon M, Luben RN, McKnight B, Mellström D, Mitchell BD, Mooser V, Moreno JM, Männistö S, O'Connell JR, Pascoe L, Peltonen L, Peral B, Perola M, Psaty BM, Salomaa V, Savage DB, Semple RK, Skaric-Juric T, Sigurdsson G, Song KS, Spector TD, Syvänen AC, Talmud PJ, Thorleifsson G, Thorsteinsdottir U, Uitterlinden AG, van Duijn CM, Vidal-Puig A, Wild SH, Wright AF, Clegg DJ, Schadt E, Wilson JF, Rudan I, Ripatti S, Borecki IB, Shuldiner AR, Ingelsson E, Jansson JO, Kaplan RC, Gudnason V, Harris TB, Groop L, Kiel DP, Rivadeneira F, Walker M, Barroso I, Vollenweider P, Waeber G, Chambers JC, Kooner JS, Soranzo N, Hirschhorn JN, Stefansson K, Wichmann HE, Ohlsson C, O'Rahilly S, Wareham NJ, Speliotes EK, Fox CS, Laakso M, Loos RJ. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet. 2011 Jun 26; 43(8):753-60. PMID: 21706003; PMCID: PMC3262230.
  1014. Verhaegh SJ, de Vogel CP, Riesbeck K, Lafontaine ER, Murphy TF, Verbrugh HA, Jaddoe VW, Hofman A, Moll HA, van Belkum A, Hays JP. Temporal development of the humoral immune response to surface antigens of Moraxella catarrhalis in young infants. Vaccine. 2011 Aug 05; 29(34):5603-10. PMID: 21704103.
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  1015. Boehringer S, van der Lijn F, Liu F, Günther M, Sinigerova S, Nowak S, Ludwig KU, Herberz R, Klein S, Hofman A, Uitterlinden AG, Niessen WJ, Breteler MM, van der Lugt A, Würtz RP, Nöthen MM, Horsthemke B, Wieczorek D, Mangold E, Kayser M. Genetic determination of human facial morphology: links between cleft-lips and normal variation. Eur J Hum Genet. 2011 Nov; 19(11):1192-7. PMID: 21694738; PMCID: PMC3198142.
  1016. Heppe DH, van Dam RM, Willemsen SP, den Breeijen H, Raat H, Hofman A, Steegers EA, Jaddoe VW. Maternal milk consumption, fetal growth, and the risks of neonatal complications: the Generation R Study. Am J Clin Nutr. 2011 Aug; 94(2):501-9. PMID: 21697074.
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  1017. Elias-Smale SE, Kavousi M, Verwoert GC, Koller MT, Steyerberg EW, Mattace-Raso FU, Hofman A, Hoeks AP, Reneman RS, Witteman JC. Common carotid intima-media thickness in cardiovascular risk stratification of older people: the Rotterdam Study. Eur J Prev Cardiol. 2012 Aug; 19(4):698-705. PMID: 21697209.
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  1018. Wieberdink RG, Ho L, Ikram MK, Koudstaal PJ, Hofman A, de Jong PT, Vingerling JR, Breteler MM. Age-related macular degeneration and the risk of stroke: the Rotterdam study. Stroke. 2011 Aug; 42(8):2138-42. PMID: 21680903.
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  1019. Gaillard R, Bakker R, Steegers EA, Hofman A, Jaddoe VW. Maternal age during pregnancy is associated with third trimester blood pressure level: the generation R study. Am J Hypertens. 2011 Sep; 24(9):1046-53. PMID: 21654855.
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  1020. den Heijer T, Tiemeier H, Luijendijk HJ, van der Lijn F, Koudstaal PJ, Hofman A, Breteler MM. A study of the bidirectional association between hippocampal volume on magnetic resonance imaging and depression in the elderly. Biol Psychiatry. 2011 Jul 15; 70(2):191-7. PMID: 21641582.
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  1021. Tromp II, Kiefte-de Jong JC, Lebon A, Renders CM, Jaddoe VW, Hofman A, de Jongste JC, Moll HA. The introduction of allergenic foods and the development of reported wheezing and eczema in childhood: the Generation R study. Arch Pediatr Adolesc Med. 2011 Oct; 165(10):933-8. PMID: 21646571.
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  1022. Ho L, van Leeuwen R, Witteman JC, van Duijn CM, Uitterlinden AG, Hofman A, de Jong PT, Vingerling JR, Klaver CC. Reducing the genetic risk of age-related macular degeneration with dietary antioxidants, zinc, and ?-3 fatty acids: the Rotterdam study. Arch Ophthalmol. 2011 Jun; 129(6):758-66. PMID: 21670343.
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  1023. Fornage M, Debette S, Bis JC, Schmidt H, Ikram MA, Dufouil C, Sigurdsson S, Lumley T, DeStefano AL, Fazekas F, Vrooman HA, Shibata DK, Maillard P, Zijdenbos A, Smith AV, Gudnason H, de Boer R, Cushman M, Mazoyer B, Heiss G, Vernooij MW, Enzinger C, Glazer NL, Beiser A, Knopman DS, Cavalieri M, Niessen WJ, Harris TB, Petrovic K, Lopez OL, Au R, Lambert JC, Hofman A, Gottesman RF, Garcia M, Heckbert SR, Atwood LD, Catellier DJ, Uitterlinden AG, Yang Q, Smith NL, Aspelund T, Romero JR, Rice K, Taylor KD, Nalls MA, Rotter JI, Sharrett R, van Duijn CM, Amouyel P, Wolf PA, Gudnason V, van der Lugt A, Boerwinkle E, Psaty BM, Seshadri S, Tzourio C, Breteler MM, Mosley TH, Schmidt R, Longstreth WT, DeCarli C, Launer LJ. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol. 2011 Jun; 69(6):928-39. PMID: 21681796; PMCID: PMC3122147.
  1024. Taal HR, Geelhoed JJ, Steegers EA, Hofman A, Moll HA, Lequin M, van der Heijden AJ, Jaddoe VW. Maternal smoking during pregnancy and kidney volume in the offspring: the Generation R Study. Pediatr Nephrol. 2011 Aug; 26(8):1275-83. PMID: 21617916; PMCID: PMC3119805.
  1025. Elias-Smale SE, Wieberdink RG, Odink AE, Hofman A, Hunink MG, Koudstaal PJ, Krestin GP, Breteler MM, van der Lugt A, Witteman JC. Burden of atherosclerosis improves the prediction of coronary heart disease but not cerebrovascular events: the Rotterdam Study. Eur Heart J. 2011 Aug; 32(16):2050-8. PMID: 21606087.
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  1026. Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A, Schnabel RB, Lubos E, Keller T, Eleftheriadis MS, Bickel C, Rupprecht HJ, Wilde S, Rossmann H, Diemert P, Cupples LA, Perret C, Erdmann J, Stark K, Kleber ME, Epstein SE, Voight BF, Kuulasmaa K, Li M, Schäfer AS, Klopp N, Braund PS, Sager HB, Demissie S, Proust C, König IR, Wichmann HE, Reinhard W, Hoffmann MM, Virtamo J, Burnett MS, Siscovick D, Wiklund PG, Qu L, El Mokthari NE, Thompson JR, Peters A, Smith AV, Yon E, Baumert J, Hengstenberg C, März W, Amouyel P, Devaney J, Schwartz SM, Saarela O, Mehta NN, Rubin D, Silander K, Hall AS, Ferrieres J, Harris TB, Melander O, Kee F, Hakonarson H, Schrezenmeir J, Gudnason V, Elosua R, Arveiler D, Evans A, Rader DJ, Illig T, Schreiber S, Bis JC, Altshuler D, Kavousi M, Witteman JC, Uitterlinden AG, Hofman A, Folsom AR, Barbalic M, Boerwinkle E, Kathiresan S, Reilly MP, O'Donnell CJ, Samani NJ, Schunkert H, Cambien F, Lackner KJ, Tiret L, Salomaa V, Munzel T, Ziegler A, Blankenberg S. A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet. 2011 Aug 01; 4(4):403-12. PMID: 21606135; PMCID: PMC3157552.
  1027. Durmus B, Kruithof CJ, Gillman MH, Willemsen SP, Hofman A, Raat H, Eilers PH, Steegers EA, Jaddoe VW. Parental smoking during pregnancy, early growth, and risk of obesity in preschool children: the Generation R Study. Am J Clin Nutr. 2011 Jul; 94(1):164-71. PMID: 21593510.
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  1028. Timmermans S, Steegers-Theunissen RP, Vujkovic M, Bakker R, den Breeijen H, Raat H, Russcher H, Lindemans J, Hofman A, Jaddoe VW, Steegers EA. Major dietary patterns and blood pressure patterns during pregnancy: the Generation R Study. Am J Obstet Gynecol. 2011 Oct; 205(4):337.e1-12. PMID: 21855845.
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  1029. Luijendijk HJ, Stricker BH, Wieberdink RG, Koudstaal PJ, Hofman A, Breteler MM, Tiemeier H. Transient ischemic attack and incident depression. Stroke. 2011 Jul; 42(7):1857-61. PMID: 21566240.
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  1030. Tas U, Steyerberg EW, Bierma-Zeinstra SM, Hofman A, Koes BW, Verhagen AP. Age, gender and disability predict future disability in older people: the Rotterdam Study. BMC Geriatr. 2011 May 10; 11:22. PMID: 21569279; PMCID: PMC3224098.
  1031. van Woudenbergh GJ, Kuijsten A, Sijbrands EJ, Hofman A, Witteman JC, Feskens EJ. Glycemic index and glycemic load and their association with C-reactive protein and incident type 2 diabetes. J Nutr Metab. 2011; 2011:623076. PMID: 21804937; PMCID: PMC3142706.
  1032. Rours GI, Duijts L, Moll HA, Arends LR, de Groot R, Jaddoe VW, Hofman A, Steegers EA, Mackenbach JP, Ott A, Willemse HF, van der Zwaan EA, Verkooijen RP, Verbrugh HA. Chlamydia trachomatis infection during pregnancy associated with preterm delivery: a population-based prospective cohort study. Eur J Epidemiol. 2011 Jun; 26(6):493-502. PMID: 21538042; PMCID: PMC3115062.
  1033. Ghassabian A, Bongers-Schokking JJ, Henrichs J, Jaddoe VW, Visser TJ, Visser W, de Muinck Keizer-Schrama SM, Hooijkaas H, Steegers EA, Hofman A, Verhulst FC, van der Ende J, de Rijke YB, Tiemeier H. Maternal thyroid function during pregnancy and behavioral problems in the offspring: the generation R study. Pediatr Res. 2011 May; 69(5 Pt 1):454-9. PMID: 21471776.
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  1034. Gaillard R, Steegers EA, Hofman A, Jaddoe VW. Associations of maternal obesity with blood pressure and the risks of gestational hypertensive disorders. The Generation R Study. J Hypertens. 2011 May; 29(5):937-44. PMID: 21430559.
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  1035. Mesker DJ, Poels MM, Ikram MA, Vernooij MW, Hofman A, Vrooman HA, van der Lugt A, Breteler MM. Lobar distribution of cerebral microbleeds: the Rotterdam Scan Study. Arch Neurol. 2011 May; 68(5):656-9. PMID: 21555643.
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  1036. Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, Wolf C, Ising M, Schreiber S, Czisch M, Müller MB, Uhr M, Bettecken T, Becker A, Schramm J, Rietschel M, Maier W, Bradley B, Ressler KJ, Nöthen MM, Cichon S, Craig IW, Breen G, Lewis CM, Hofman A, Tiemeier H, van Duijn CM, Holsboer F, Müller-Myhsok B, Binder EB. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 2011 Apr 28; 70(2):252-65. PMID: 21521612; PMCID: PMC3112053.
  1037. Velders FP, Dieleman G, Henrichs J, Jaddoe VW, Hofman A, Verhulst FC, Hudziak JJ, Tiemeier H. Prenatal and postnatal psychological symptoms of parents and family functioning: the impact on child emotional and behavioural problems. Eur Child Adolesc Psychiatry. 2011 Jul; 20(7):341-50. PMID: 21523465; PMCID: PMC3135831.
  1038. Duncan EL, Danoy P, Kemp JP, Leo PJ, McCloskey E, Nicholson GC, Eastell R, Prince RL, Eisman JA, Jones G, Sambrook PN, Reid IR, Dennison EM, Wark J, Richards JB, Uitterlinden AG, Spector TD, Esapa C, Cox RD, Brown SD, Thakker RV, Addison KA, Bradbury LA, Center JR, Cooper C, Cremin C, Estrada K, Felsenberg D, Glüer CC, Hadler J, Henry MJ, Hofman A, Kotowicz MA, Makovey J, Nguyen SC, Nguyen TV, Pasco JA, Pryce K, Reid DM, Rivadeneira F, Roux C, Stefansson K, Styrkarsdottir U, Thorleifsson G, Tichawangana R, Evans DM, Brown MA. Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. PLoS Genet. 2011 Apr; 7(4):e1001372. PMID: 21533022; PMCID: PMC3080863.
  1039. Smith NL, Huffman JE, Strachan DP, Huang J, Dehghan A, Trompet S, Lopez LM, Shin SY, Baumert J, Vitart V, Bis JC, Wild SH, Rumley A, Yang Q, Uitterlinden AG, Stott DJ, Davies G, Carter AM, Thorand B, Polašek O, McKnight B, Campbell H, Rudnicka AR, Chen MH, Buckley BM, Harris SE, Peters A, Pulanic D, Lumley T, de Craen AJ, Liewald DC, Gieger C, Campbell S, Ford I, Gow AJ, Luciano M, Porteous DJ, Guo X, Sattar N, Tenesa A, Cushman M, Slagboom PE, Visscher PM, Spector TD, Illig T, Rudan I, Bovill EG, Wright AF, McArdle WL, Tofler G, Hofman A, Westendorp RG, Starr JM, Grant PJ, Karakas M, Hastie ND, Psaty BM, Wilson JF, Lowe GD, O'Donnell CJ, Witteman JC, Jukema JW, Deary IJ, Soranzo N, Koenig W, Hayward C. Genetic predictors of fibrin D-dimer levels in healthy adults. Circulation. 2011 May 03; 123(17):1864-72. PMID: 21502573; PMCID: PMC3095913.
  1040. Zhai G, Teumer A, Stolk L, Perry JR, Vandenput L, Coviello AD, Koster A, Bell JT, Bhasin S, Eriksson J, Eriksson A, Ernst F, Ferrucci L, Frayling TM, Glass D, Grundberg E, Haring R, Hedman AK, Hofman A, Kiel DP, Kroemer HK, Liu Y, Lunetta KL, Maggio M, Lorentzon M, Mangino M, Melzer D, Miljkovic I, Nica A, Penninx BW, Vasan RS, Rivadeneira F, Small KS, Soranzo N, Uitterlinden AG, Völzke H, Wilson SG, Xi L, Zhuang WV, Harris TB, Murabito JM, Ohlsson C, Murray A, de Jong FH, Spector TD, Wallaschofski H. Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. PLoS Genet. 2011 Apr; 7(4):e1002025. PMID: 21533175; PMCID: PMC3077384.
  1041. Ernst GD, de Jonge LL, Hofman A, Lindemans J, Russcher H, Steegers EA, Jaddoe VW. C-reactive protein levels in early pregnancy, fetal growth patterns, and the risk for neonatal complications: the Generation R Study. Am J Obstet Gynecol. 2011 Aug; 205(2):132.e1-12. PMID: 21575931.
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  1042. Schrijvers EM, Koudstaal PJ, Hofman A, Breteler MM. Plasma clusterin and the risk of Alzheimer disease. JAMA. 2011 Apr 06; 305(13):1322-6. PMID: 21467285.
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  1043. Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, Bilbao A, de Boer RA, Beury D, Bots ML, Breetvelt EJ, Cauchi S, Cavalcanti-Proença C, Chambers JC, Clarke TK, Dahmen N, de Geus EJ, Dick D, Ducci F, Easton A, Edenberg HJ, Esko T, Esk T, Fernández-Medarde A, Foroud T, Freimer NB, Girault JA, Grobbee DE, Guarrera S, Gudbjartsson DF, Hartikainen AL, Heath AC, Hesselbrock V, Hofman A, Hottenga JJ, Isohanni MK, Kaprio J, Khaw KT, Kuehnel B, Laitinen J, Lobbens S, Luan J, Mangino M, Maroteaux M, Matullo G, McCarthy MI, Mueller C, Navis G, Numans ME, Núñez A, Nyholt DR, Onland-Moret CN, Oostra BA, O'Reilly PF, Palkovits M, Penninx BW, Polidoro S, Pouta A, Prokopenko I, Ricceri F, Santos E, Smit JH, Soranzo N, Song K, Sovio U, Stumvoll M, Surakk I, Thorgeirsson TE, Thorsteinsdottir U, Troakes C, Tyrfingsson T, Tönjes A, Uiterwaal CS, Uitterlinden AG, van der Harst P, van der Schouw YT, Staehlin O, Vogelzangs N, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Whitfield JB, Wichmann EH, Willemsen G, Witteman JC, Yuan X, Zhai G, Zhao JH, Zhang W, Martin NG, Metspalu A, Doering A, Scott J, Spector TD, Loos RJ, Boomsma DI, Mooser V, Peltonen L, Stefansson K, van Duijn CM, Vineis P, Sommer WH, Kooner JS, Spanagel R, Heberlein UA, Jarvelin MR, Elliott P. Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7119-24. PMID: 21471458; PMCID: PMC3084048.
  1044. El Marroun H, Hudziak JJ, Tiemeier H, Creemers H, Steegers EA, Jaddoe VW, Hofman A, Verhulst FC, van den Brink W, Huizink AC. Intrauterine cannabis exposure leads to more aggressive behavior and attention problems in 18-month-old girls. Drug Alcohol Depend. 2011 Nov 01; 118(2-3):470-4. PMID: 21470799.
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  1045. Székely E, Tiemeier H, Arends LR, Jaddoe VW, Hofman A, Verhulst FC, Herba CM. Recognition of facial expressions of emotions by 3-year-olds. Emotion. 2011 Apr; 11(2):425-35. PMID: 21500910.
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  1046. Krijthe BP, Walter S, Newson RS, Hofman A, Hunink MG, Tiemeier H. Is positive affect associated with survival? A population-based study of elderly persons. Am J Epidemiol. 2011 Jun 01; 173(11):1298-307. PMID: 21454828.
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  1047. Demirkan A, Amin N, Isaacs A, Jarvelin MR, Whitfield JB, Wichmann HE, Kyvik KO, Rudan I, Gieger C, Hicks AA, Johansson Å, Hottenga JJ, Smith JJ, Wild SH, Pedersen NL, Willemsen G, Mangino M, Hayward C, Uitterlinden AG, Hofman A, Witteman J, Montgomery GW, Pietiläinen KH, Rantanen T, Kaprio J, Döring A, Pramstaller PP, Gyllensten U, de Geus EJ, Penninx BW, Wilson JF, Rivadeneria F, Magnusson PK, Boomsma DI, Spector T, Campbell H, Hoehne B, Martin NG, Oostra BA, McCarthy M, Peltonen-Palotie L, Aulchenko Y, Visscher PM, Ripatti S, Janssens AC, van Duijn CM. Genetic architecture of circulating lipid levels. Eur J Hum Genet. 2011 Jul; 19(7):813-9. PMID: 21448234; PMCID: PMC3137496.
  1048. Ligthart L, de Vries B, Smith AV, Ikram MA, Amin N, Hottenga JJ, Koelewijn SC, Kattenberg VM, de Moor MH, Janssens AC, Aulchenko YS, Oostra BA, de Geus EJ, Smit JH, Zitman FG, Uitterlinden AG, Hofman A, Willemsen G, Nyholt DR, Montgomery GW, Terwindt GM, Gudnason V, Penninx BW, Breteler M, Ferrari MD, Launer LJ, van Duijn CM, van den Maagdenberg AM, Boomsma DI. Meta-analysis of genome-wide association for migraine in six population-based European cohorts. Eur J Hum Genet. 2011 Aug; 19(8):901-7. PMID: 21448238; PMCID: PMC3172930.
  1049. de Jonge LL, van Osch-Gevers L, Willemsen SP, Steegers EA, Hofman A, Helbing WA, Jaddoe VW. Growth, obesity, and cardiac structures in early childhood: the Generation R Study. Hypertension. 2011 May; 57(5):934-40. PMID: 21444837.
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  1050. Ramdas WD, van Koolwijk LM, Lemij HG, Pasutto F, Cree AJ, Thorleifsson G, Janssen SF, Jacoline TB, Amin N, Rivadeneira F, Wolfs RC, Walters GB, Jonasson F, Weisschuh N, Mardin CY, Gibson J, Zegers RH, Hofman A, de Jong PT, Uitterlinden AG, Oostra BA, Thorsteinsdottir U, Gramer E, Welgen-Lüssen UC, Kirwan JF, Bergen AA, Reis A, Stefansson K, Lotery AJ, Vingerling JR, Jansonius NM, Klaver CC, van Duijn CM. Common genetic variants associated with open-angle glaucoma. Hum Mol Genet. 2011 Jun 15; 20(12):2464-71. PMID: 21427129.
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  1051. Teichert M, van Noord C, Uitterlinden AG, Hofman A, Buhre PN, De Smet PA, Straus S, Stricker BH, Visser LE. Proton pump inhibitors and the risk of overanticoagulation during acenocoumarol maintenance treatment. Br J Haematol. 2011 May; 153(3):379-85. PMID: 21418179.
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  1052. Newson RS, Boelen PA, Hek K, Hofman A, Tiemeier H. The prevalence and characteristics of complicated grief in older adults. J Affect Disord. 2011 Jul; 132(1-2):231-8. PMID: 21397336.
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  1053. Snijder CA, Brouwers MM, Jaddoe VW, Hofman A, Roeleveld N, Burdorf A. Occupational exposure to endocrine disruptors and time to pregnancy among couples in a large birth cohort study: the Generation R Study. Fertil Steril. 2011 May; 95(6):2067-72. PMID: 21392747.
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  1054. Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand SS, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth AJ, Barnes TA, Becker DM, Becker LC, Berger K, Bis JC, Boekholdt SM, Boerwinkle E, Braund PS, Brown MJ, Burnett MS, Buysschaert I, Carlquist JF, Chen L, Cichon S, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney JM, Diemert P, Do R, Doering A, Eifert S, Mokhtari NE, Ellis SG, Elosua R, Engert JC, Epstein SE, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B, Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Halperin E, Hammond N, Hazen SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA, Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R, Lambrechts D, Leander K, Lettre G, Li M, Lieb W, Loley C, Lotery AJ, Mannucci PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O, Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Münzel T, Musunuru K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Patel RS, Patterson CC, Peters A, Peyvandi F, Qu L, Quyyumi AA, Rader DJ, Rallidis LS, Rice C, Rosendaal FR, Rubin D, Salomaa V, Sampietro ML, Sandhu MS, Schadt E, Schäfer A, Schillert A, Schreiber S, Schrezenmeir J, Schwartz SM, Siscovick DS, Sivananthan M, Sivapalaratnam S, Smith A, Smith TB, Snoep JD, Soranzo N, Spertus JA, Stark K, Stirrups K, Stoll M, Tang WH, Tennstedt S, Thorgeirsson G, Thorleifsson G, Tomaszewski M, Uitterlinden AG, van Rij AM, Voight BF, Wareham NJ, Wells GA, Wichmann HE, Wild PS, Willenborg C, Witteman JC, Wright BJ, Ye S, Zeller T, Ziegler A, Cambien F, Goodall AH, Cupples LA, Quertermous T, März W, Hengstenberg C, Blankenberg S, Ouwehand WH, Hall AS, Deloukas P, Thompson JR, Stefansson K, Roberts R, Thorsteinsdottir U, O'Donnell CJ, McPherson R, Erdmann J, Samani NJ. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 Mar 06; 43(4):333-8. PMID: 21378990; PMCID: PMC3119261.
  1055. Fox ER, Young JH, Li Y, Dreisbach AW, Keating BJ, Musani SK, Liu K, Morrison AC, Ganesh S, Kutlar A, Ramachandran VS, Polak JF, Fabsitz RR, Dries DL, Farlow DN, Redline S, Adeyemo A, Hirschorn JN, Sun YV, Wyatt SB, Penman AD, Palmas W, Rotter JI, Townsend RR, Doumatey AP, Tayo BO, Mosley TH, Lyon HN, Kang SJ, Rotimi CN, Cooper RS, Franceschini N, Curb JD, Martin LW, Eaton CB, Kardia SL, Taylor HA, Caulfield MJ, Ehret GB, Johnson T, Chakravarti A, Zhu X, Levy D. Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet. 2011 Jun 01; 20(11):2273-84. PMID: 21378095; PMCID: PMC3090190.
  1056. Medici M, van der Deure WM, Verbiest M, Vermeulen SH, Hansen PS, Kiemeney LA, Hermus AR, Breteler MM, Hofman A, Hegedüs L, Kyvik KO, den Heijer M, Uitterlinden AG, Visser TJ, Peeters RP. A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels. Eur J Endocrinol. 2011 May; 164(5):781-8. PMID: 21367965.
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  1057. IJsselstijn L, Dekker LJ, Koudstaal PJ, Hofman A, Sillevis Smitt PA, Breteler MM, Luider TM. Serum clusterin levels are not increased in presymptomatic Alzheimer's disease. J Proteome Res. 2011 Apr 01; 10(4):2006-10. PMID: 21280673.
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  1058. Direk N, Newson RS, Hofman A, Kirschbaum C, Tiemeier H. Short and long-term effects of smoking on cortisol in older adults. Int J Psychophysiol. 2011 May; 80(2):157-60. PMID: 21333696.
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  1059. Ramdas WD, Wolfs RC, Hofman A, de Jong PT, Vingerling JR, Jansonius NM. Lifestyle and risk of developing open-angle glaucoma: the Rotterdam study. Arch Ophthalmol. 2011 Jun; 129(6):767-72. PMID: 21320952.
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  1060. Velders FP, Kuningas M, Kumari M, Dekker MJ, Uitterlinden AG, Kirschbaum C, Hek K, Hofman A, Verhulst FC, Kivimaki M, Van Duijn CM, Walker BR, Tiemeier H. Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach. Psychoneuroendocrinology. 2011 Aug; 36(7):1053-61. PMID: 21316860; PMCID: PMC3940151.
  1061. Wolff NJ, Darlington AS, Hunfeld JA, Tharner A, Van Ijzendoorn MH, Bakermans-Kranenburg MJ, Moll HA, Jaddoe VW, Hofman A, Verhulst FC, Passchier J, Tiemeier H. The influence of attachment and temperament on venipuncture distress in 14-month-old infants: the Generation R Study. Infant Behav Dev. 2011 Apr; 34(2):293-302. PMID: 21316110.
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  1062. Poels MM, Ikram MA, van der Lugt A, Hofman A, Krestin GP, Breteler MM, Vernooij MW. Incidence of cerebral microbleeds in the general population: the Rotterdam Scan Study. Stroke. 2011 Mar; 42(3):656-61. PMID: 21307170.
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  1063. Mook-Kanamori DO, Marsh JA, Warrington NM, Taal HR, Newnham JP, Beilin LJ, Lye SJ, Palmer LJ, Hofman A, Steegers EA, Pennell CE, Jaddoe VW. Variants near CCNL1/LEKR1 and in ADCY5 and fetal growth characteristics in different trimesters. J Clin Endocrinol Metab. 2011 May; 96(5):E810-5. PMID: 21307140.
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  1064. Dehghan A, Dupuis J, Barbalic M, Bis JC, Eiriksdottir G, Lu C, Pellikka N, Wallaschofski H, Kettunen J, Henneman P, Baumert J, Strachan DP, Fuchsberger C, Vitart V, Wilson JF, Paré G, Naitza S, Rudock ME, Surakka I, de Geus EJ, Alizadeh BZ, Guralnik J, Shuldiner A, Tanaka T, Zee RY, Schnabel RB, Nambi V, Kavousi M, Ripatti S, Nauck M, Smith NL, Smith AV, Sundvall J, Scheet P, Liu Y, Ruokonen A, Rose LM, Larson MG, Hoogeveen RC, Freimer NB, Teumer A, Tracy RP, Launer LJ, Buring JE, Yamamoto JF, Folsom AR, Sijbrands EJ, Pankow J, Elliott P, Keaney JF, Sun W, Sarin AP, Fontes JD, Badola S, Astor BC, Hofman A, Pouta A, Werdan K, Greiser KH, Kuss O, Meyer zu Schwabedissen HE, Thiery J, Jamshidi Y, Nolte IM, Soranzo N, Spector TD, Völzke H, Parker AN, Aspelund T, Bates D, Young L, Tsui K, Siscovick DS, Guo X, Rotter JI, Uda M, Schlessinger D, Rudan I, Hicks AA, Penninx BW, Thorand B, Gieger C, Coresh J, Willemsen G, Harris TB, Uitterlinden AG, Järvelin MR, Rice K, Radke D, Salomaa V, Willems van Dijk K, Boerwinkle E, Vasan RS, Ferrucci L, Gibson QD, Bandinelli S, Snieder H, Boomsma DI, Xiao X, Campbell H, Hayward C, Pramstaller PP, van Duijn CM, Peltonen L, Psaty BM, Gudnason V, Ridker PM, Homuth G, Koenig W, Ballantyne CM, Witteman JC, Benjamin EJ, Perola M, Chasman DI. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation. 2011 Feb 22; 123(7):731-8. PMID: 21300955; PMCID: PMC3147232.
  1065. El Barzouhi A, Elias-Smale S, Dehghan A, Vliegenthart-Proença R, Oudkerk M, Hofman A, Witteman JC. Renal function is related to severity of coronary artery calcification in elderly persons: the Rotterdam study. PLoS One. 2011 Feb 02; 6(2):e16738. PMID: 21311747; PMCID: PMC3032739.
  1066. Luijendijk HJ, van den Berg JF, Hofman A, Tiemeier H, Stricker BH. ß-blockers and the risk of incident depression in the elderly. J Clin Psychopharmacol. 2011 Feb; 31(1):45-50. PMID: 21192142.
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  1067. Ay L, Jaddoe VW, Hofman A, Moll HA, Raat H, Steegers EA, Hokken-Koelega AC. Foetal and postnatal growth and bone mass at 6 months: the Generation R Study. Clin Endocrinol (Oxf). 2011 Feb; 74(2):181-90. PMID: 21050252.
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  1068. Durmus B, van Rossem L, Duijts L, Arends LR, Raat H, Moll HA, Hofman A, Steegers EA, Jaddoe VW. Breast-feeding and growth in children until the age of 3 years: the Generation R Study. Br J Nutr. 2011 Jun; 105(11):1704-11. PMID: 21276279.
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  1069. Lebon A, Verkaik NJ, Labout JA, de Vogel CP, Hooijkaas H, Verbrugh HA, van Wamel WJ, Jaddoe VW, Hofman A, Hermans PW, Ma J, Mitchell TJ, Moll HA, van Belkum A. Natural antibodies against several pneumococcal virulence proteins in children during the pre-pneumococcal-vaccine era: the generation R study. Infect Immun. 2011 Apr; 79(4):1680-7. PMID: 21282409; PMCID: PMC3067559.
  1070. Heppe DH, Steegers EA, Timmermans S, Breeijen Hd, Tiemeier H, Hofman A, Jaddoe VW. Maternal fish consumption, fetal growth and the risks of neonatal complications: the Generation R Study. Br J Nutr. 2011 Mar; 105(6):938-49. PMID: 21266095.
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  1071. Jansen PW, Saridjan NS, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H. Does disturbed sleeping precede symptoms of anxiety or depression in toddlers? The generation R study. Psychosom Med. 2011 Apr; 73(3):242-9. PMID: 21257976.
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  1072. Simón-Sánchez J, van Hilten JJ, van de Warrenburg B, Post B, Berendse HW, Arepalli S, Hernandez DG, de Bie RM, Velseboer D, Scheffer H, Bloem B, van Dijk KD, Rivadeneira F, Hofman A, Uitterlinden AG, Rizzu P, Bochdanovits Z, Singleton AB, Heutink P. Genome-wide association study confirms extant PD risk loci among the Dutch. Eur J Hum Genet. 2011 Jun; 19(6):655-61. PMID: 21248740; PMCID: PMC3110043.
  1073. Durmus B, Ay L, Hokken-Koelega AC, Raat H, Hofman A, Steegers EA, Jaddoe VW. Maternal smoking during pregnancy and subcutaneous fat mass in early childhood. The Generation R Study. Eur J Epidemiol. 2011 Apr; 26(4):295-304. PMID: 21229294; PMCID: PMC3088815.
  1074. Kuningas M, Altmäe S, Uitterlinden AG, Hofman A, van Duijn CM, Tiemeier H. The relationship between fertility and lifespan in humans. Age (Dordr). 2011 Dec; 33(4):615-22. PMID: 21222045; PMCID: PMC3220400.
  1075. van den Hooven EH, de Kluizenaar Y, Pierik FH, Hofman A, van Ratingen SW, Zandveld PY, Mackenbach JP, Steegers EA, Miedema HM, Jaddoe VW. Air pollution, blood pressure, and the risk of hypertensive complications during pregnancy: the generation R study. Hypertension. 2011 Mar; 57(3):406-12. PMID: 21220700.
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  1076. Timmermans S, Bonsel GJ, Steegers-Theunissen RP, Mackenbach JP, Steyerberg EW, Raat H, Verbrug