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R. John Collier, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yang NJ, Isensee J, Neel DV, Quadros AU, Zhang HB, Lauzadis J, Liu SM, Shiers S, Belu A, Palan S, Marlin S, Maignel J, Kennedy-Curran A, Tong VS, Moayeri M, Röderer P, Nitzsche A, Lu M, Pentelute BL, Brüstle O, Tripathi V, Foster KA, Price TJ, Collier RJ, Leppla SH, Puopolo M, Bean BP, Cunha TM, Hucho T, Chiu IM. Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons. Nat Neurosci. 2022 Feb; 25(2):168-179. PMID: 34931070.
    Citations:    Fields:    
  2. Loftis AR, Zhang G, Backlund C, Quartararo AJ, Pishesha N, Hanna CC, Schissel CK, Garafola D, Loas A, Collier RJ, Ploegh H, Irvine DJ, Pentelute BL. An in vivo selection-derived d-peptide for engineering erythrocyte-binding antigens that promote immune tolerance. Proc Natl Acad Sci U S A. 2021 08 24; 118(34). PMID: 34417313.
    Citations:    Fields:    Translation:AnimalsCells
  3. Collier RJ, Casadevall A. The Holobiont/Hologenome Concept Series. mBio. 2016 Apr 14; 7(2):e00605-16. PMID: 27084955.
    Citations:    Fields:    Translation:Humans
  4. Collier RJ. A tribute to Sjur: Sjur Olsnes, 1939-2014. Pathog Dis. 2015 Nov; 73(8):ftv077. PMID: 26432819.
    Citations:    Fields:    Translation:Humans
  5. Jiang J, Pentelute BL, Collier RJ, Zhou ZH. Atomic structure of anthrax protective antigen pore elucidates toxin translocation. Nature. 2015 May 28; 521(7553):545-9. PMID: 25778700.
    Citations: 102     Fields:    Translation:Cells
  6. Sharma O, Collier RJ. Polylysine-mediated translocation of the diphtheria toxin catalytic domain through the anthrax protective antigen pore. Biochemistry. 2014 Nov 11; 53(44):6934-40. PMID: 25317832.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  7. Naik S, Brock S, Akkaladevi N, Tally J, McGinn-Straub W, Zhang N, Gao P, Gogol EP, Pentelute BL, Collier RJ, Fisher MT. Monitoring the kinetics of the pH-driven transition of the anthrax toxin prepore to the pore by biolayer interferometry and surface plasmon resonance. Biochemistry. 2013 Sep 17; 52(37):6335-47. PMID: 23964683.
    Citations: 15     Fields:    Translation:HumansCells
  8. McCluskey AJ, Collier RJ. Receptor-directed chimeric toxins created by sortase-mediated protein fusion. Mol Cancer Ther. 2013 Oct; 12(10):2273-81. PMID: 23945077.
    Citations: 16     Fields:    Translation:HumansCells
  9. Gogol EP, Akkaladevi N, Szerszen L, Mukherjee S, Chollet-Hinton L, Katayama H, Pentelute BL, Collier RJ, Fisher MT. Three dimensional structure of the anthrax toxin translocon-lethal factor complex by cryo-electron microscopy. Protein Sci. 2013 May; 22(5):586-94. PMID: 23494942.
    Citations: 19     Fields:    Translation:Cells
  10. Akkaladevi N, Hinton-Chollet L, Katayama H, Mitchell J, Szerszen L, Mukherjee S, Gogol EP, Pentelute BL, Collier RJ, Fisher MT. Assembly of anthrax toxin pore: lethal-factor complexes into lipid nanodiscs. Protein Sci. 2013 Apr; 22(4):492-501. PMID: 23389868.
    Citations: 15     Fields:    
  11. Slater LH, Hett EC, Mark K, Chumbler NM, Patel D, Lacy DB, Collier RJ, Hung DT. Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death. ACS Chem Biol. 2013 Apr 19; 8(4):812-22. PMID: 23343607.
    Citations: 7     Fields:    Translation:AnimalsCells
  12. McCluskey AJ, Olive AJ, Starnbach MN, Collier RJ. Targeting HER2-positive cancer cells with receptor-redirected anthrax protective antigen. Mol Oncol. 2013 Jun; 7(3):440-51. PMID: 23290417.
    Citations: 35     Fields:    Translation:HumansCells
  13. Mechaly A, McCluskey AJ, Collier RJ. Changing the receptor specificity of anthrax toxin. mBio. 2012; 3(3). PMID: 22550037.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  14. Rodnin MV, Kyrychenko A, Kienker P, Sharma O, Vargas-Uribe M, Collier RJ, Finkelstein A, Ladokhin AS. Replacement of C-terminal histidines uncouples membrane insertion and translocation in diphtheria toxin T-domain. Biophys J. 2011 Nov 16; 101(10):L41-3. PMID: 22098755.
    Citations: 18     Fields:    Translation:Cells
  15. Fischer A, Holden MA, Pentelute BL, Collier RJ. Ultrasensitive detection of protein translocated through toxin pores in droplet-interface bilayers. Proc Natl Acad Sci U S A. 2011 Oct 04; 108(40):16577-81. PMID: 21949363.
    Citations: 13     Fields:    
  16. Janowiak BE, Jennings-Antipov LD, Collier RJ. Cys-Cys cross-linking shows contact between the N-terminus of lethal factor and Phe427 of the anthrax toxin pore. Biochemistry. 2011 May 03; 50(17):3512-6. PMID: 21425869.
    Citations: 7     Fields:    Translation:Cells
  17. Pentelute BL, Sharma O, Collier RJ. Chemical dissection of protein translocation through the anthrax toxin pore. Angew Chem Int Ed Engl. 2011 Mar 01; 50(10):2294-6. PMID: 21351339.
    Citations: 22     Fields:    Translation:AnimalsCells
  18. Jennings-Antipov LD, Song L, Collier RJ. Interactions of anthrax lethal factor with protective antigen defined by site-directed spin labeling. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):1868-73. PMID: 21262847.
    Citations: 11     Fields:    
  19. Dmochewitz L, Lillich M, Kaiser E, Jennings LD, Lang AE, Buchner J, Fischer G, Aktories K, Collier RJ, Barth H. Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen. Cell Microbiol. 2011 Mar; 13(3):359-73. PMID: 20946244.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  20. Zornetta I, Brandi L, Janowiak B, Dal Molin F, Tonello F, Collier RJ, Montecucco C. Imaging the cell entry of the anthrax oedema and lethal toxins with fluorescent protein chimeras. Cell Microbiol. 2010 Oct; 12(10):1435-45. PMID: 20438574.
    Citations: 22     Fields:    Translation:AnimalsCells
  21. Rodnin MV, Kyrychenko A, Kienker P, Sharma O, Posokhov YO, Collier RJ, Finkelstein A, Ladokhin AS. Conformational switching of the diphtheria toxin T domain. J Mol Biol. 2010 Sep 10; 402(1):1-7. PMID: 20654627.
    Citations: 24     Fields:    Translation:Cells
  22. Collier RJ. Microbiology. Salmonella's safety catch. Science. 2010 May 21; 328(5981):981-2. PMID: 20489009.
    Citations:    Fields:    Translation:HumansCells
  23. Sun J, Collier RJ. Disulfide bonds in the ectodomain of anthrax toxin receptor 2 are required for the receptor-bound protective-antigen pore to function. PLoS One. 2010 May 10; 5(5):e10553. PMID: 20479891.
    Citations: 12     Fields:    Translation:AnimalsCells
  24. Pentelute BL, Barker AP, Janowiak BE, Kent SB, Collier RJ. A semisynthesis platform for investigating structure-function relationships in the N-terminal domain of the anthrax Lethal Factor. ACS Chem Biol. 2010 Apr 16; 5(4):359-64. PMID: 20180595.
    Citations: 19     Fields:    Translation:Cells
  25. Katayama H, Wang J, Tama F, Chollet L, Gogol EP, Collier RJ, Fisher MT. Three-dimensional structure of the anthrax toxin pore inserted into lipid nanodiscs and lipid vesicles. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3453-7. PMID: 20142512.
    Citations: 57     Fields:    Translation:Cells
  26. Janowiak BE, Fischer A, Collier RJ. Effects of introducing a single charged residue into the phenylalanine clamp of multimeric anthrax protective antigen. J Biol Chem. 2010 Mar 12; 285(11):8130-7. PMID: 20061382.
    Citations: 14     Fields:    Translation:Cells
  27. Vernier G, Wang J, Jennings LD, Sun J, Fischer A, Song L, Collier RJ. Solubilization and characterization of the anthrax toxin pore in detergent micelles. Protein Sci. 2009 Sep; 18(9):1882-95. PMID: 19609933.
    Citations: 14     Fields:    Translation:Cells
  28. Wang J, Vernier G, Fischer A, Collier RJ. Functions of phenylalanine residues within the beta-barrel stem of the anthrax toxin pore. PLoS One. 2009 Jul 17; 4(7):e6280. PMID: 19609431.
    Citations: 4     Fields:    Translation:Cells
  29. Collier RJ. Membrane translocation by anthrax toxin. Mol Aspects Med. 2009 Dec; 30(6):413-22. PMID: 19563824.
    Citations: 70     Fields:    Translation:AnimalsCells
  30. Basilio D, Juris SJ, Collier RJ, Finkelstein A. Evidence for a proton-protein symport mechanism in the anthrax toxin channel. J Gen Physiol. 2009 Mar; 133(3):307-14. PMID: 19204186.
    Citations: 26     Fields:    Translation:Cells
  31. Janowiak BE, Finkelstein A, Collier RJ. An approach to characterizing single-subunit mutations in multimeric prepores and pores of anthrax protective antigen. Protein Sci. 2009 Feb; 18(2):348-58. PMID: 19165720.
    Citations: 10     Fields:    Translation:AnimalsCells
  32. Lang AE, Neumeyer T, Sun J, Collier RJ, Benz R, Aktories K. Amino acid residues involved in membrane insertion and pore formation of Clostridium botulinum C2 toxin. Biochemistry. 2008 Aug 12; 47(32):8406-13. PMID: 18636745.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  33. Katayama H, Janowiak BE, Brzozowski M, Juryck J, Falke S, Gogol EP, Collier RJ, Fisher MT. GroEL as a molecular scaffold for structural analysis of the anthrax toxin pore. Nat Struct Mol Biol. 2008 Jul; 15(7):754-60. PMID: 18568038.
    Citations: 58     Fields:    Translation:Cells
  34. Kim C, Wilcox-Adelman S, Sano Y, Tang WJ, Collier RJ, Park JM. Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus. Proc Natl Acad Sci U S A. 2008 Apr 22; 105(16):6150-5. PMID: 18427110.
    Citations: 40     Fields:    Translation:AnimalsCells
  35. Sun J, Lang AE, Aktories K, Collier RJ. Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation. Proc Natl Acad Sci U S A. 2008 Mar 18; 105(11):4346-51. PMID: 18334631.
    Citations: 40     Fields:    Translation:AnimalsCells
  36. Bolcome RE, Sullivan SE, Zeller R, Barker AP, Collier RJ, Chan J. Anthrax lethal toxin induces cell death-independent permeability in zebrafish vasculature. Proc Natl Acad Sci U S A. 2008 Feb 19; 105(7):2439-44. PMID: 18268319.
    Citations: 31     Fields:    Translation:Animals
  37. Wimalasena DS, Cramer JC, Janowiak BE, Juris SJ, Melnyk RA, Anderson DE, Kirk KL, Collier RJ, Bann JG. Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation, and translocation. Biochemistry. 2007 Dec 25; 46(51):14928-36. PMID: 18044973.
    Citations: 19     Fields:    Translation:AnimalsCells
  38. Rogers MS, Christensen KA, Birsner AE, Short SM, Wigelsworth DJ, Collier RJ, D'Amato RJ. Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth. Cancer Res. 2007 Oct 15; 67(20):9980-5. PMID: 17942931.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  39. Juris SJ, Melnyk RA, Bolcome RE, Chan J, Collier RJ. Cross-linked forms of the isolated N-terminal domain of the lethal factor are potent inhibitors of anthrax toxin. Infect Immun. 2007 Oct; 75(10):5052-8. PMID: 17635861.
    Citations: 6     Fields:    Translation:AnimalsCells
  40. Scobie HM, Marlett JM, Rainey GJ, Lacy DB, Collier RJ, Young JA. Anthrax toxin receptor 2 determinants that dictate the pH threshold of toxin pore formation. PLoS One. 2007 Mar 28; 2(3):e329. PMID: 17389920.
    Citations: 29     Fields:    Translation:AnimalsCells
  41. Young JA, Collier RJ. Anthrax toxin: receptor binding, internalization, pore formation, and translocation. Annu Rev Biochem. 2007; 76:243-65. PMID: 17335404.
    Citations: 302     Fields:    Translation:HumansAnimalsCells
  42. Sun J, Vernier G, Wigelsworth DJ, Collier RJ. Insertion of anthrax protective antigen into liposomal membranes: effects of a receptor. J Biol Chem. 2007 Jan 12; 282(2):1059-65. PMID: 17107945.
    Citations: 30     Fields:    Translation:HumansCells
  43. Scobie HM, Wigelsworth DJ, Marlett JM, Thomas D, Rainey GJ, Lacy DB, Manchester M, Collier RJ, Young JA. Anthrax toxin receptor 2-dependent lethal toxin killing in vivo. PLoS Pathog. 2006 Oct; 2(10):e111. PMID: 17054395.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  44. Rivera J, Nakouzi A, Abboud N, Revskaya E, Goldman D, Collier RJ, Dadachova E, Casadevall A. A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1. Infect Immun. 2006 Jul; 74(7):4149-56. PMID: 16790789.
    Citations: 32     Fields:    Translation:AnimalsCells
  45. Melnyk RA, Collier RJ. A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation. Proc Natl Acad Sci U S A. 2006 Jun 27; 103(26):9802-7. PMID: 16785422.
    Citations: 28     Fields:    Translation:Cells
  46. Christensen KA, Krantz BA, Collier RJ. Assembly and disassembly kinetics of anthrax toxin complexes. Biochemistry. 2006 Feb 21; 45(7):2380-6. PMID: 16475827.
    Citations: 9     Fields:    Translation:Cells
  47. Krantz BA, Finkelstein A, Collier RJ. Protein translocation through the anthrax toxin transmembrane pore is driven by a proton gradient. J Mol Biol. 2006 Feb 03; 355(5):968-79. PMID: 16343527.
    Citations: 107     Fields:    Translation:AnimalsCells
  48. Melnyk RA, Hewitt KM, Lacy DB, Lin HC, Gessner CR, Li S, Woods VL, Collier RJ. Structural determinants for the binding of anthrax lethal factor to oligomeric protective antigen. J Biol Chem. 2006 Jan 20; 281(3):1630-5. PMID: 16293620.
    Citations: 27     Fields:    Translation:Cells
  49. Lacy DB, Lin HC, Melnyk RA, Schueler-Furman O, Reither L, Cunningham K, Baker D, Collier RJ. A model of anthrax toxin lethal factor bound to protective antigen. Proc Natl Acad Sci U S A. 2005 Nov 08; 102(45):16409-14. PMID: 16251269.
    Citations: 36     Fields:    Translation:Cells
  50. Wolfe JT, Krantz BA, Rainey GJ, Young JA, Collier RJ. Whole-cell voltage clamp measurements of anthrax toxin pore current. J Biol Chem. 2005 Nov 25; 280(47):39417-22. PMID: 16183642.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  51. Rainey GJ, Wigelsworth DJ, Ryan PL, Scobie HM, Collier RJ, Young JA. Receptor-specific requirements for anthrax toxin delivery into cells. Proc Natl Acad Sci U S A. 2005 Sep 13; 102(37):13278-83. PMID: 16141341.
    Citations: 69     Fields:    Translation:Cells
  52. Scobie HM, Thomas D, Marlett JM, Destito G, Wigelsworth DJ, Collier RJ, Young JA, Manchester M. A soluble receptor decoy protects rats against anthrax lethal toxin challenge. J Infect Dis. 2005 Sep 15; 192(6):1047-51. PMID: 16107958.
    Citations: 44     Fields:    Translation:AnimalsCells
  53. Krantz BA, Melnyk RA, Zhang S, Juris SJ, Lacy DB, Wu Z, Finkelstein A, Collier RJ. A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore. Science. 2005 Jul 29; 309(5735):777-81. PMID: 16051798.
    Citations: 154     Fields:    Translation:Cells
  54. Qa'dan M, Christensen KA, Zhang L, Roberts TM, Collier RJ. Membrane insertion by anthrax protective antigen in cultured cells. Mol Cell Biol. 2005 Jul; 25(13):5492-8. PMID: 15964805.
    Citations: 7     Fields:    Translation:AnimalsCells
  55. Aulinger BA, Roehrl MH, Mekalanos JJ, Collier RJ, Wang JY. Combining anthrax vaccine and therapy: a dominant-negative inhibitor of anthrax toxin is also a potent and safe immunogen for vaccines. Infect Immun. 2005 Jun; 73(6):3408-14. PMID: 15908368.
    Citations: 28     Fields:    Translation:AnimalsPHPublic Health
  56. Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, Falkow S, Galan JE, Gottesman M, Gourse R, Grindley ND, Gross CA, Grossman A, Hochschild A, Howe M, Hurwitz J, Isberg RR, Kaplan S, Kornberg A, Kustu SG, Landick RC, Landy A, Levy SB, Losick R, Long SR, Maloy SR, Mekalanos JJ, Neidhardt FC, Pace NR, Ptashne M, Roberts JW, Roth JR, Rothman-Denes LB, Salyers A, Schaechter M, Shapiro L, Silhavy TJ, Simon MI, Walker G, Yanofsky C, Zinder N. An open letter to Elias Zerhouni. Science. 2005 Mar 04; 307(5714):1409-10. PMID: 15746409.
    Citations: 3     Fields:    Translation:PHPublic Health
  57. Christensen KA, Krantz BA, Melnyk RA, Collier RJ. Interaction of the 20 kDa and 63 kDa fragments of anthrax protective antigen: kinetics and thermodynamics. Biochemistry. 2005 Jan 25; 44(3):1047-53. PMID: 15654761.
    Citations: 12     Fields:    Translation:Cells
  58. Krantz BA, Trivedi AD, Cunningham K, Christensen KA, Collier RJ. Acid-induced unfolding of the amino-terminal domains of the lethal and edema factors of anthrax toxin. J Mol Biol. 2004 Nov 26; 344(3):739-56. PMID: 15533442.
    Citations: 73     Fields:    Translation:Cells
  59. Zhang S, Finkelstein A, Collier RJ. Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel. Proc Natl Acad Sci U S A. 2004 Nov 30; 101(48):16756-61. PMID: 15548616.
    Citations: 70     Fields:    Translation:AnimalsCells
  60. Oh KJ, Barbuto S, Meyer N, Kim RS, Collier RJ, Korsmeyer SJ. Conformational changes in BID, a pro-apoptotic BCL-2 family member, upon membrane binding. A site-directed spin labeling study. J Biol Chem. 2005 Jan 07; 280(1):753-67. PMID: 15501827.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  61. Zhang S, Udho E, Wu Z, Collier RJ, Finkelstein A. Protein translocation through anthrax toxin channels formed in planar lipid bilayers. Biophys J. 2004 Dec; 87(6):3842-9. PMID: 15377524.
    Citations: 58     Fields:    Translation:Cells
  62. Pimental RA, Christensen KA, Krantz BA, Collier RJ. Anthrax toxin complexes: heptameric protective antigen can bind lethal factor and edema factor simultaneously. Biochem Biophys Res Commun. 2004 Sep 10; 322(1):258-62. PMID: 15313199.
    Citations: 20     Fields:    Translation:Cells
  63. Lacy DB, Wigelsworth DJ, Melnyk RA, Harrison SC, Collier RJ. Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation. Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13147-51. PMID: 15326297.
    Citations: 123     Fields:    Translation:Cells
  64. Boll W, Ehrlich M, Collier RJ, Kirchhausen T. Effects of dynamin inactivation on pathways of anthrax toxin uptake. Eur J Cell Biol. 2004 Jul; 83(6):281-8. PMID: 15511085.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  65. Ladokhin AS, Legmann R, Collier RJ, White SH. Reversible refolding of the diphtheria toxin T-domain on lipid membranes. Biochemistry. 2004 Jun 15; 43(23):7451-8. PMID: 15182188.
    Citations: 26     Fields:    Translation:Cells
  66. Zhang S, Cunningham K, Collier RJ. Anthrax protective antigen: efficiency of translocation is independent of the number of ligands bound to the prepore. Biochemistry. 2004 May 25; 43(20):6339-43. PMID: 15147218.
    Citations: 6     Fields:    Translation:AnimalsCells
  67. Lacy DB, Wigelsworth DJ, Scobie HM, Young JA, Collier RJ. Crystal structure of the von Willebrand factor A domain of human capillary morphogenesis protein 2: an anthrax toxin receptor. Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6367-72. PMID: 15079089.
    Citations: 57     Fields:    Translation:HumansCells
  68. Wigelsworth DJ, Krantz BA, Christensen KA, Lacy DB, Juris SJ, Collier RJ. Binding stoichiometry and kinetics of the interaction of a human anthrax toxin receptor, CMG2, with protective antigen. J Biol Chem. 2004 May 28; 279(22):23349-56. PMID: 15044490.
    Citations: 90     Fields:    Translation:HumansCells
  69. Mourez M, Collier RJ. Use of phage display and polyvalency to design inhibitors of protein-protein interactions. Methods Mol Biol. 2004; 261:213-28. PMID: 15064461.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  70. Turk BE, Wong TY, Schwarzenbacher R, Jarrell ET, Leppla SH, Collier RJ, Liddington RC, Cantley LC. The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat Struct Mol Biol. 2004 Jan; 11(1):60-6. PMID: 14718924.
    Citations: 68     Fields:    Translation:HumansCells
  71. Mourez M, Yan M, Lacy DB, Dillon L, Bentsen L, Marpoe A, Maurin C, Hotze E, Wigelsworth D, Pimental RA, Ballard JD, Collier RJ, Tweten RK. Mapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):13803-8. PMID: 14623961.
    Citations: 37     Fields:    Translation:AnimalsCells
  72. Rhie GE, Roehrl MH, Mourez M, Collier RJ, Mekalanos JJ, Wang JY. A dually active anthrax vaccine that confers protection against both bacilli and toxins. Proc Natl Acad Sci U S A. 2003 Sep 16; 100(19):10925-30. PMID: 12960361.
    Citations: 39     Fields:    Translation:AnimalsCells
  73. Croney JC, Cunningham KM, Collier RJ, Jameson DM. Fluorescence resonance energy transfer studies on anthrax lethal toxin. FEBS Lett. 2003 Aug 28; 550(1-3):175-8. PMID: 12935906.
    Citations: 1     Fields:    Translation:AnimalsCells
  74. Starnbach MN, Collier RJ. Anthrax delivers a lethal blow to host immunity. Nat Med. 2003 Aug; 9(8):996-7. PMID: 12894159.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  75. Gao-Sheridan S, Zhang S, Collier RJ. Exchange characteristics of calcium ions bound to anthrax protective antigen. Biochem Biophys Res Commun. 2003 Jan 03; 300(1):61-4. PMID: 12480521.
    Citations: 9     Fields:    Translation:Cells
  76. Collier RJ, Young JA. Anthrax toxin. Annu Rev Cell Dev Biol. 2003; 19:45-70. PMID: 14570563.
    Citations: 255     Fields:    Translation:HumansAnimals
  77. Yan M, Collier RJ. Characterization of dominant-negative forms of anthrax protective antigen. Mol Med. 2003 Jan-Feb; 9(1-2):46-51. PMID: 12765339.
    Citations: 16     Fields:    Translation:AnimalsCells
  78. Mourez M, Lacy DB, Cunningham K, Legmann R, Sellman BR, Mogridge J, Collier RJ. 2001: a year of major advances in anthrax toxin research. Trends Microbiol. 2002 Jun; 10(6):287-93. PMID: 12088665.
    Citations: 24     Fields:    Translation:Animals
  79. Cunningham K, Lacy DB, Mogridge J, Collier RJ. Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen. Proc Natl Acad Sci U S A. 2002 May 14; 99(10):7049-53. PMID: 11997439.
    Citations: 78     Fields:    Translation:AnimalsCells
  80. Mogridge J, Cunningham K, Lacy DB, Mourez M, Collier RJ. The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen. Proc Natl Acad Sci U S A. 2002 May 14; 99(10):7045-8. PMID: 11997437.
    Citations: 85     Fields:    Translation:Cells
  81. Nassi S, Collier RJ, Finkelstein A. PA63 channel of anthrax toxin: an extended beta-barrel. Biochemistry. 2002 Feb 05; 41(5):1445-50. PMID: 11814336.
    Citations: 63     Fields:    Translation:Cells
  82. Mogridge J, Cunningham K, Collier RJ. Stoichiometry of anthrax toxin complexes. Biochemistry. 2002 Jan 22; 41(3):1079-82. PMID: 11790132.
    Citations: 99     Fields:    Translation:Cells
  83. Lacy DB, Collier RJ. Structure and function of anthrax toxin. Curr Top Microbiol Immunol. 2002; 271:61-85. PMID: 12224524.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  84. Wedekind JE, Trame CB, Dorywalska M, Koehl P, Raschke TM, McKee M, FitzGerald D, Collier RJ, McKay DB. Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity. J Mol Biol. 2001 Dec 07; 314(4):823-37. PMID: 11734000.
    Citations: 45     Fields:    Translation:Cells
  85. Lacy DB, Mourez M, Fouassier A, Collier RJ. Mapping the anthrax protective antigen binding site on the lethal and edema factors. J Biol Chem. 2002 Jan 25; 277(4):3006-10. PMID: 11714723.
    Citations: 46     Fields:    Translation:AnimalsCells
  86. Paoletti LC, Peterson DL, Legmann R, Collier RJ. Preclinical evaluation of group B streptococcal polysaccharide conjugate vaccines prepared with a modified diphtheria toxin and a recombinant duck hepatitis B core antigen. Vaccine. 2001 Nov 12; 20(3-4):370-6. PMID: 11672899.
    Citations: 4     Fields:    Translation:AnimalsCells
  87. Pannifer AD, Wong TY, Schwarzenbacher R, Renatus M, Petosa C, Bienkowska J, Lacy DB, Collier RJ, Park S, Leppla SH, Hanna P, Liddington RC. Crystal structure of the anthrax lethal factor. Nature. 2001 Nov 08; 414(6860):229-33. PMID: 11700563.
    Citations: 120     Fields:    Translation:Cells
  88. Bradley KA, Mogridge J, Mourez M, Collier RJ, Young JA. Identification of the cellular receptor for anthrax toxin. Nature. 2001 Nov 08; 414(6860):225-9. PMID: 11700562.
    Citations: 391     Fields:    Translation:HumansAnimalsCells
  89. Collier RJ. Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century. Toxicon. 2001 Nov; 39(11):1793-803. PMID: 11595641.
    Citations: 111     Fields:    
  90. Mourez M, Kane RS, Mogridge J, Metallo S, Deschatelets P, Sellman BR, Whitesides GM, Collier RJ. Designing a polyvalent inhibitor of anthrax toxin. Nat Biotechnol. 2001 Oct; 19(10):958-61. PMID: 11581662.
    Citations: 72     Fields:    Translation:AnimalsCells
  91. Liu XH, Collier RJ, Youle RJ. Inhibition of axotomy-induced neuronal apoptosis by extracellular delivery of a Bcl-XL fusion protein. J Biol Chem. 2001 Dec 07; 276(49):46326-32. PMID: 11574549.
    Citations: 20     Fields:    Translation:AnimalsCells
  92. Van Dover CL, Humphris SE, Fornari D, Cavanaugh CM, Collier R, Goffredi SK, Hashimoto J, Lilley MD, Reysenbach AL, Shank TM, Von Damm KL, Banta A, Gallant RM, Gotz D, Green D, Hall J, Harmer TL, Hurtado LA, Johnson P, McKiness ZP, Meredith C, Olson E, Pan IL, Turnipseed M, Won Y, Young CR, Vrijenhoek RC. Biogeography and ecological setting of Indian Ocean hydrothermal vents. Science. 2001 Oct 26; 294(5543):818-23. PMID: 11557843.
    Citations: 37     Fields:    Translation:AnimalsCells
  93. Sellman BR, Mourez M, Collier RJ. Dominant-negative mutants of a toxin subunit: an approach to therapy of anthrax. Science. 2001 Apr 27; 292(5517):695-7. PMID: 11326092.
    Citations: 73     Fields:    Translation:AnimalsCells
  94. Crawford MJ, Krishnamoorthy RR, Rudick VL, Collier RJ, Kapin M, Aggarwal BB, Al-Ubaidi MR, Agarwal N. Bcl-2 overexpression protects photooxidative stress-induced apoptosis of photoreceptor cells via NF-kappaB preservation. Biochem Biophys Res Commun. 2001 Mar; 281(5):1304-12. PMID: 11243878.
    Citations: 8     Fields:    Translation:AnimalsCells
  95. Mogridge J, Mourez M, Collier RJ. Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin. J Bacteriol. 2001 Mar; 183(6):2111-6. PMID: 11222612.
    Citations: 30     Fields:    Translation:AnimalsCells
  96. Sellman BR, Nassi S, Collier RJ. Point mutations in anthrax protective antigen that block translocation. J Biol Chem. 2001 Mar 16; 276(11):8371-6. PMID: 11113126.
    Citations: 42     Fields:    Translation:AnimalsCells
  97. Finkelstein A, Oh KJ, Senzel L, Gordon M, Blaustein RO, Collier RJ. The diphtheria toxin channel-forming T-domain translocates its own NH2-terminal region and the catalytic domain across planar phospholipid bilayers. Int J Med Microbiol. 2000 Oct; 290(4-5):435-40. PMID: 11111923.
    Citations: 8     Fields:    Translation:Cells
  98. Elliott JL, Mogridge J, Collier RJ. A quantitative study of the interactions of Bacillus anthracis edema factor and lethal factor with activated protective antigen. Biochemistry. 2000 Jun 06; 39(22):6706-13. PMID: 10828989.
    Citations: 37     Fields:    Translation:AnimalsCells
  99. Beauregard KE, Collier RJ, Swanson JA. Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization. Cell Microbiol. 2000 Jun; 2(3):251-8. PMID: 11207581.
    Citations: 45     Fields:    Translation:AnimalsCells
  100. Senzel L, Gordon M, Blaustein RO, Oh KJ, Collier RJ, Finkelstein A. Topography of diphtheria Toxin's T domain in the open channel state. J Gen Physiol. 2000 Apr; 115(4):421-34. PMID: 10736310.
    Citations: 37     Fields:    Translation:HumansCells
  101. Zarozinski CC, Collier RJ, Starnbach MN. Use of anthrax toxin fusions to stimulate immune responses. Methods Enzymol. 2000; 326:542-51. PMID: 11036663.
    Citations: 1     Fields:    Translation:AnimalsCells
  102. Oh KJ, Altenbach C, Collier RJ, Hubbell WL. Site-directed spin labeling of proteins. Applications to diphtheria toxin. Methods Mol Biol. 2000; 145:147-69. PMID: 10820721.
    Citations: 30     Fields:    Translation:Cells
  103. Lodaya R, Blanke SR, Collier RJ, Slama JT. Photoaffinity labeling of diphtheria toxin fragment A with 8-azidoadenosyl nicotinamide adenine dinucleotide. Biochemistry. 1999 Oct 19; 38(42):13877-86. PMID: 10529233.
    Citations:    Fields:    Translation:Cells
  104. Miller CJ, Elliott JL, Collier RJ. Anthrax protective antigen: prepore-to-pore conversion. Biochemistry. 1999 Aug 10; 38(32):10432-41. PMID: 10441138.
    Citations: 115     Fields:    Translation:Cells
  105. Oh KJ, Zhan H, Cui C, Altenbach C, Hubbell WL, Collier RJ. Conformation of the diphtheria toxin T domain in membranes: a site-directed spin-labeling study of the TH8 helix and TL5 loop. Biochemistry. 1999 Aug 10; 38(32):10336-43. PMID: 10441127.
    Citations: 20     Fields:    Translation:Cells
  106. Collier RJ. Mechanism of membrane translocation by anthrax toxin: insertion and pore formation by protective antigen J Appl Microbiol. 1999 Aug; 87(2):283. PMID: 10475967.
    Citations: 5     Fields:    
  107. Liddington R, Pannifer A, Hanna P, Leppla S, Collier RJ. Crystallographic studies of the anthrax lethal toxin J Appl Microbiol. 1999 Aug; 87(2):282. PMID: 10475966.
    Citations: 1     Fields:    
  108. Oh KJ, Senzel L, Collier RJ, Finkelstein A. Translocation of the catalytic domain of diphtheria toxin across planar phospholipid bilayers by its own T domain. Proc Natl Acad Sci U S A. 1999 Jul 20; 96(15):8467-70. PMID: 10411898.
    Citations: 51     Fields:    Translation:Cells
  109. Doling AM, Ballard JD, Shen H, Krishna KM, Ahmed R, Collier RJ, Starnbach MN. Cytotoxic T-lymphocyte epitopes fused to anthrax toxin induce protective antiviral immunity. Infect Immun. 1999 Jul; 67(7):3290-6. PMID: 10377103.
    Citations: 10     Fields:    Translation:AnimalsCells
  110. Beauregard KE, Wimer-Mackin S, Collier RJ, Lencer WI. Anthrax toxin entry into polarized epithelial cells. Infect Immun. 1999 Jun; 67(6):3026-30. PMID: 10338515.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  111. Ren J, Kachel K, Kim H, Malenbaum SE, Collier RJ, London E. Interaction of diphtheria toxin T domain with molten globule-like proteins and its implications for translocation. Science. 1999 May 07; 284(5416):955-7. PMID: 10320374.
    Citations: 39     Fields:    Translation:Cells
  112. Ren J, Sharpe JC, Collier RJ, London E. Membrane translocation of charged residues at the tips of hydrophobic helices in the T domain of diphtheria toxin. Biochemistry. 1999 Jan 19; 38(3):976-84. PMID: 9893993.
    Citations: 11     Fields:    Translation:Cells
  113. Zhan H, Elliott JL, Shen WH, Huynh PD, Finkelstein A, Collier RJ. Effects of mutations in proline 345 on insertion of diphtheria toxin into model membranes. J Membr Biol. 1999 Jan 15; 167(2):173-81. PMID: 9916148.
    Citations: 6     Fields:    Translation:AnimalsCells
  114. Malenbaum SE, Collier RJ, London E. Membrane topography of the T domain of diphtheria toxin probed with single tryptophan mutants. Biochemistry. 1998 Dec 22; 37(51):17915-22. PMID: 9922159.
    Citations: 10     Fields:    Translation:Cells
  115. Wesche J, Elliott JL, Falnes PO, Olsnes S, Collier RJ. Characterization of membrane translocation by anthrax protective antigen. Biochemistry. 1998 Nov 10; 37(45):15737-46. PMID: 9843379.
    Citations: 85     Fields:    Translation:AnimalsCells
  116. Ballard JD, Collier RJ, Starnbach MN. Anthrax toxin as a molecular tool for stimulation of cytotoxic T lymphocytes: disulfide-linked epitopes, multiple injections, and role of CD4(+) cells. Infect Immun. 1998 Oct; 66(10):4696-9. PMID: 9746566.
    Citations: 9     Fields:    Translation:AnimalsCells
  117. Kachel K, Ren J, Collier RJ, London E. Identifying transmembrane states and defining the membrane insertion boundaries of hydrophobic helices in membrane-inserted diphtheria toxin T domain. J Biol Chem. 1998 Sep 04; 273(36):22950-6. PMID: 9722516.
    Citations: 22     Fields:    Translation:Cells
  118. Senzel L, Huynh PD, Jakes KS, Collier RJ, Finkelstein A. The diphtheria toxin channel-forming T domain translocates its own NH2-terminal region across planar bilayers. J Gen Physiol. 1998 Sep; 112(3):317-24. PMID: 9725891.
    Citations: 27     Fields:    Translation:Cells
  119. Benson EL, Huynh PD, Finkelstein A, Collier RJ. Identification of residues lining the anthrax protective antigen channel. Biochemistry. 1998 Mar 17; 37(11):3941-8. PMID: 9521715.
    Citations: