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James Chodosh, M.D.

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Mentoring
current student opportunities
Available: 08/01/12, Expires: 07/01/21

Our laboratory’s long-term goal is to connect genomics and pathogenesis for ocular adenovirus infections. Rapid growth in the number of whole adenovirus genomes in GenBank affords new opportunities to identify genomic correlates of tissue tropism and virulence. Members of the laboratory employ a full range of in vivo, in vitro, and in silico techniques, permitting us to answer questions ranging from how adenoviruses cause specific disease manifestations at the molecular level, to how new adenoviral pathogens evolve.

Available: 07/01/17, Expires: 06/30/20

Human adenoviruses within species D evolve principally through homologous recombination during co-infections. Recently, species D adenoviruses have undergone a rapid expansion, with severe consequences for infected patients. The student will develop in vitro models of viral co-infection to identify basic mechanisms of genetic recombination among human adenoviruses. This project may involve basic bioinformatics as well as wet bench methods.

completed student projects
Sterile Vitritis in the Setting of a Boston Keratoprosthesis
Full Time/Year Long, 07/01/13 - 06/30/14
Identifying Different Roles of Cornea Stromal Cells in the Adenovirus 37 Keratitis Mouse Model
Summer, 06/15/09 - 07/31/09

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
  1. R01EY021558 (RAJAIYA, JAYA) Sep 30, 2011 - Jun 30, 2021
    NIH/NEI
    Endocytosis in Adenoviral Ocular Pathogenesis
    Role: Co-Principal Investigator
  2. R03EY015222 (CHODOSH, JAMES) Jan 1, 2004 - Dec 31, 2007
    NIH/NEI
    Genetics of Ocular Adenoviruses
    Role: Principal Investigator
  3. R01EY013124 (CHODOSH, JAMES) Jul 1, 2000 - Mar 31, 2021
    NIH/NEI
    Immunopathogenesis of Adenovirus Keratitis
    Role: Principal Investigator
  4. K08EY000357 (CHODOSH, JAMES) Jul 1, 1996 - Nov 30, 2000
    NIH/NEI
    IMMUNOPATHOLOGY OF ADENOVIRUS KERATITIS
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Paschalis EI, Lei F, Zhou C, Kapoulea V, Dana R, Chodosh J, Vavvas DG, Dohlman CH. Permanent neuroglial remodeling of the retina following infiltration of CSF1R inhibition-resistant peripheral monocytes. Proc Natl Acad Sci U S A. 2018 Nov 15. PMID: 30442669.
    View in: PubMed
  2. Shanbhag SS, Saeed HN, Colby KA, Chodosh J. Comparative Outcomes of Boston Keratoprosthesis Type 1 Implantation Based on Vision in the Contralateral Eye. Cornea. 2018 Nov; 37(11):1408-1413. PMID: 30179893.
    View in: PubMed
  3. Pan H, Yan Y, Zhang J, Zhao S, Feng L, Ou J, Cao N, Li M, Zhao W, Wan C, Ismail AM, Rajaiya J, Chodosh J, Zhang Q. Rapid Construction of a Replication-Competent Infectious Clone of Human Adenovirus Type 14 by Gibson Assembly. Viruses. 2018 Oct 18; 10(10). PMID: 30340336.
    View in: PubMed
  4. Ismail AM, Lee JS, Lee JY, Singh G, Dyer DW, Seto D, Chodosh J, Rajaiya J. Adenoviromics: Mining the Human Adenovirus Species D Genome. Front Microbiol. 2018; 9:2178. PMID: 30254627.
    View in: PubMed
  5. Avadhanam VS, Zarei-Ghanavati M, Bardan AS, Iyer G, Srinivasan B, Agarwal S, Goweida M, Masahiko F, Hille K, Chodosh J, Liu CS. When there is no tooth - Looking beyond the Falcinelli MOOKP. Ocul Surf. 2018 Aug 28. PMID: 30170034.
    View in: PubMed
  6. Lee JY, Lee JS, Materne EC, Rajala R, Ismail AM, Seto D, Dyer DW, Rajaiya J, Chodosh J. Bacterial RecA Protein Promotes Adenoviral Recombination during In Vitro Infection. mSphere. 2018 06 27; 3(3). PMID: 29925671.
    View in: PubMed
  7. Sié A, Diarra A, Millogo O, Zongo A, Lebas E, Bärnighausen T, Chodosh J, Porco TC, Deiner MS, Lietman TM, Keenan JD, Oldenburg CE. Seasonal and Temporal Trends in Childhood Conjunctivitis in Burkina Faso. Am J Trop Med Hyg. 2018 Jul; 99(1):229-232. PMID: 29761759.
    View in: PubMed
  8. Paschalis EI, Lei F, Zhou C, Kapoulea V, Thanos A, Dana R, Vavvas DG, Chodosh J, Dohlman CH. The Role of Microglia and Peripheral Monocytes in Retinal Damage after Corneal Chemical Injury. Am J Pathol. 2018 Jul; 188(7):1580-1596. PMID: 29630857.
    View in: PubMed
  9. Gonzalez-Andrades M, Sharifi R, Islam MM, Divoux T, Haist M, Paschalis EI, Gelfand L, Mamodaly S, Di Cecilia L, Cruzat A, Ulm FJ, Chodosh J, Delori F, Dohlman CH. Improving the practicality and safety of artificial corneas: Pre-assembly and gamma-rays sterilization of the Boston Keratoprosthesis. Ocul Surf. 2018 Jul; 16(3):322-330. PMID: 29627599.
    View in: PubMed
  10. Lee CS, Lee AY, Akileswaran L, Stroman D, Najafi-Tagol K, Kleiboeker S, Chodosh J, Magaret A, Wald A, Van Gelder RN. Determinants of Outcomes of Adenoviral Keratoconjunctivitis. Ophthalmology. 2018 Sep; 125(9):1344-1353. PMID: 29602567.
    View in: PubMed
  11. Shanbhag SS, Saeed HN, Paschalis EI, Chodosh J. Boston keratoprosthesis type 1 for limbal stem cell deficiency after severe chemical corneal injury: A systematic review. Ocul Surf. 2018 Jul; 16(3):272-281. PMID: 29597010.
    View in: PubMed
  12. Ismail AM, Cui T, Dommaraju K, Singh G, Dehghan S, Seto J, Shrivastava S, Fedorova NB, Gupta N, Stockwell TB, Madupu R, Heim A, Kajon AE, Romanowski EG, Kowalski RP, Malathi J, Therese KL, Madhavan HN, Zhang Q, Ferreyra LJ, Jones MS, Rajaiya J, Dyer DW, Chodosh J, Seto D. Genomic analysis of a large set of currently-and historically-important human adenovirus pathogens. Emerg Microbes Infect. 2018 Feb 07; 7(1):10. PMID: 29410402.
    View in: PubMed
  13. Deiner MS, McLeod SD, Chodosh J, Oldenburg CE, Fathy CA, Lietman TM, Porco TC. Clinical Age-Specific Seasonal Conjunctivitis Patterns and Their Online Detection in Twitter, Blog, Forum, and Comment Social Media Posts. Invest Ophthalmol Vis Sci. 2018 02 01; 59(2):910-920. PMID: 29450538.
    View in: PubMed
  14. Dohlman CH, Cade F, Regatieri CV, Zhou C, Lei F, Crnej A, Harissi-Dagher M, Robert MC, Papaliodis GN, Chen D, Aquavella JV, Akpek EK, Aldave AJ, Sippel KC, D'Amico DJ, Dohlman JG, Fagerholm P, Wang L, Shen LQ, González-Andrades M, Chodosh J, Kenyon KR, Foster CS, Pineda R, Melki S, Colby KA, Ciolino JB, Vavvas DG, Kinoshita S, Dana R, Paschalis EI. Chemical Burns of the Eye: The Role of Retinal Injury and New Therapeutic Possibilities. Cornea. 2018 Feb; 37(2):248-251. PMID: 29135604.
    View in: PubMed
  15. White KD, Abe R, Ardern-Jones M, Beachkofsky T, Bouchard C, Carleton B, Chodosh J, Cibotti R, Davis R, Denny JC, Dodiuk-Gad RP, Ergen EN, Goldman JL, Holmes JH, Hung SI, Lacouture ME, Lehloenya RJ, Mallal S, Manolio TA, Micheletti RG, Mitchell CM, Mockenhaupt M, Ostrov DA, Pavlos R, Pirmohamed M, Pope E, Redwood A, Rosenbach M, Rosenblum MD, Roujeau JC, Saavedra AP, Saeed HN, Struewing JP, Sueki H, Sukasem C, Sung C, Trubiano JA, Weintraub J, Wheatley LM, Williams KB, Worley B, Chung WH, Shear NH, Phillips EJ. SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation. J Allergy Clin Immunol Pract. 2018 Jan - Feb; 6(1):38-69. PMID: 29310768.
    View in: PubMed
  16. Cruzat A, Gonzalez-Andrades M, Mauris J, AbuSamra DB, Chidambaram P, Kenyon KR, Chodosh J, Dohlman CH, Argüeso P. Colocalization of Galectin-3 With CD147 Is Associated With Increased Gelatinolytic Activity in Ulcerating Human Corneas. Invest Ophthalmol Vis Sci. 2018 01 01; 59(1):223-230. PMID: 29340650.
    View in: PubMed
  17. Shanbhag SS, Saeed HN, Paschalis EI, Chodosh J. Keratolimbal allograft for limbal stem cell deficiency after severe corneal chemical injury: a systematic review. Br J Ophthalmol. 2018 Aug; 102(8):1114-1121. PMID: 29141906.
    View in: PubMed
  18. Choi CJ, Jakobiec FA, Zakka FR, Foster CS, Chodosh J, Freitag SK. Conjunctival Squamous Cell Neoplasia Associated With Ocular Cicatricial Pemphigoid. Ophthalmic Plast Reconstr Surg. 2017 Nov/Dec; 33(6):e157-e160. PMID: 28509683.
    View in: PubMed
  19. Taniguchi EV, Paschalis EI, Crnej A, Ren A, Colby KA, Chodosh J, Pasquale LR, Shen LQ, Dohlman CH, Cruzat A. The Role of the Back Plate in Angle Anatomy with the Boston Type I Keratoprosthesis. Cornea. 2017 Sep; 36(9):1096-1101. PMID: 28614155.
    View in: PubMed
  20. Saeed HN, Shanbhag S, Chodosh J. The Boston keratoprosthesis. Curr Opin Ophthalmol. 2017 Jul; 28(4):390-396. PMID: 28383302.
    View in: PubMed
  21. Li H, Reksten TR, Ice JA, Kelly JA, Adrianto I, Rasmussen A, Wang S, He B, Grundahl KM, Glenn SB, Miceli-Richard C, Bowman S, Lester S, Eriksson P, Eloranta ML, Brun JG, Gøransson LG, Harboe E, Guthridge JM, Kaufman KM, Kvarnström M, Cunninghame Graham DS, Patel K, Adler AJ, Farris AD, Brennan MT, Chodosh J, Gopalakrishnan R, Weisman MH, Venuturupalli S, Wallace DJ, Hefner KS, Houston GD, Huang AJW, Hughes PJ, Lewis DM, Radfar L, Vista ES, Edgar CE, Rohrer MD, Stone DU, Vyse TJ, Harley JB, Gaffney PM, James JA, Turner S, Alevizos I, Anaya JM, Rhodus NL, Segal BM, Montgomery CG, Scofield RH, Kovats S, Mariette X, Rönnblom L, Witte T, Rischmueller M, Wahren-Herlenius M, Omdal R, Jonsson R, Ng WF, Nordmark G, Lessard CJ, Sivils KL. Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons. PLoS Genet. 2017 Jun; 13(6):e1006820. PMID: 28640813.
    View in: PubMed
  22. Barton K, Chodosh J, Jonas JB. Highlights from this issue. Br J Ophthalmol. 2017 May; 101(5):i. PMID: 28424172.
    View in: PubMed
  23. Paschalis EI, Zhou C, Lei F, Scott N, Kapoulea V, Robert MC, Vavvas D, Dana R, Chodosh J, Dohlman CH. Mechanisms of Retinal Damage after Ocular Alkali Burns. Am J Pathol. 2017 Jun; 187(6):1327-1342. PMID: 28412300.
    View in: PubMed
  24. Ramke M, Lee JY, Dyer DW, Seto D, Rajaiya J, Chodosh J. The 5'UTR in human adenoviruses: leader diversity in late gene expression. Sci Rep. 2017 04 04; 7(1):618. PMID: 28377580.
    View in: PubMed
  25. Poon LY, Chodosh J, Vavvas DG, Dohlman CH, Chen TC. Endoscopic Cyclophotocoagulation for the Treatment of Glaucoma in Boston Keratoprosthesis Type II Patient. J Glaucoma. 2017 Apr; 26(4):e146-e149. PMID: 28079656.
    View in: PubMed
  26. Choi CJ, Stagner AM, Jakobiec FA, Chodosh J, Yoon MK. Eyelid Mass in Boston Keratoprosthesis Type 2. Ophthalmic Plast Reconstr Surg. 2017 Mar/Apr; 33(2):e39-e41. PMID: 27163939.
    View in: PubMed
  27. Kaliki S, Freitag SK, Chodosh J. Nodulo-Ulcerative Ocular Surface Squamous Neoplasia in 6 Patients: A Rare Presentation. Cornea. 2017 Mar; 36(3):322-326. PMID: 27749454.
    View in: PubMed
  28. Cruzat A, Shukla AN, Arafat SN, Alageel S, Colon C, Chodosh J, Ciolino JB. Ex Vivo Study of Transepithelial Corneal Cross-linking. J Refract Surg. 2017 Mar 01; 33(3):171-177. PMID: 28264131.
    View in: PubMed
  29. Stryjewski TP, Chodosh J, Kim IK, Barshak MB, Miller JB. Severe corneal ulcer with progression to endophthalmitis and high-grade bacteremia. Am J Ophthalmol Case Rep. 2017 Jun; 6:30-32. PMID: 29260050.
    View in: PubMed
  30. Barton K, Chodosh J, Jonas J. Highlights from this issue. Br J Ophthalmol. 2017 Feb; 101(2):i. PMID: 28108480.
    View in: PubMed
  31. Rao R, Saeed HN, Chodosh J. Advances in Imaging of Ocular Surface Tumors. Int Ophthalmol Clin. 2017; 57(4):21-29. PMID: 28885244.
    View in: PubMed
  32. Wolkow N, Chodosh J, Freitag SK. Innovations in Treatment of Lagophthalmos and Exposure Keratopathy. Int Ophthalmol Clin. 2017; 57(4):85-103. PMID: 28885249.
    View in: PubMed
  33. Barton K, Chodosh J, Jonas J. Highlights from this issue. Br J Ophthalmol. 2016 Dec; 100(12):i. PMID: 27879263.
    View in: PubMed
  34. Yu Z, Zeng Z, Zhang J, Pan Y, Chen M, Guo Y, Yu N, Chodosh J, Fu N, Che X, Zhang Q. Fatal Community-acquired Pneumonia in Children Caused by Re-emergent Human Adenovirus 7d Associated with Higher Severity of Illness and Fatality Rate. Sci Rep. 2016 11 16; 6:37216. PMID: 27848998.
    View in: PubMed
  35. Saeed HN, Chodosh J. Ocular manifestations of Stevens-Johnson syndrome and their management. Curr Opin Ophthalmol. 2016 Nov; 27(6):522-529. PMID: 27585215.
    View in: PubMed
  36. Jain R, Sharma N, Basu S, Iyer G, Ueta M, Sotozono C, Kannibiran C, Rathi VM, Gupta N, Kinoshita S, Gomes JA, Chodosh J, Sangwan VS. Reply: amniotic membrane transplantation in Stevens-Johnson syndrome. Surv Ophthalmol. 2017 Mar - Apr; 62(2):249-250. PMID: 27751824.
    View in: PubMed
  37. Ismail AM, Lee JS, Dyer DW, Seto D, Rajaiya J, Chodosh J. Selection Pressure in the Human Adenovirus Fiber Knob Drives Cell Specificity in Epidemic Keratoconjunctivitis. J Virol. 2016 Nov 01; 90(21):9598-9607. PMID: 27512073.
    View in: PubMed
  38. Yousuf MA, Lee JS, Zhou X, Ramke M, Lee JY, Chodosh J, Rajaiya J. Protein kinase C Signaling in Adenoviral Infection. Biochemistry. 2016 Oct 04. PMID: 27700064.
    View in: PubMed
  39. Deiner MS, Lietman TM, McLeod SD, Chodosh J, Porco TC. Surveillance Tools Emerging From Search Engines and Social Media Data for Determining Eye Disease Patterns. JAMA Ophthalmol. 2016 Sep 01; 134(9):1024-30. PMID: 27416554.
    View in: PubMed
  40. Zhou X, Ramke M, Chintakuntlawar AV, Lee JY, Rajaiya J, Chodosh J. Role of MyD88 in adenovirus keratitis. Immunol Cell Biol. 2017 01; 95(1):108-116. PMID: 27528076.
    View in: PubMed
  41. Lee R, Khoueir Z, Tsikata E, Chodosh J, Dohlman CH, Chen TC. Long-term Visual Outcomes and Complications of Boston Keratoprosthesis Type II Implantation. Ophthalmology. 2017 01; 124(1):27-35. PMID: 27538795.
    View in: PubMed
  42. Homayounfar G, Grassi CM, Al-Moujahed A, Colby KA, Dohlman CH, Chodosh J. Boston keratoprosthesis type I in the elderly. Br J Ophthalmol. 2017 04; 101(4):514-518. PMID: 27381593.
    View in: PubMed
  43. Saeed HN, Kohanim S, Le HG, Chodosh J, Jacobs DS. Stevens-Johnson Syndrome and Corneal Ectasia: Management and a Case for Association. Am J Ophthalmol. 2016 09; 169:276-281. PMID: 27386788.
    View in: PubMed
  44. Davies E, Chodosh J. Infections after keratoprosthesis. Curr Opin Ophthalmol. 2016 Jul; 27(4):373-7. PMID: 27138637.
    View in: PubMed
  45. Robert MC, Arafat SN, Spurr-Michaud S, Chodosh J, Dohlman CH, Gipson IK. Tear Matrix Metalloproteinases and Myeloperoxidase Levels in Patients With Boston Keratoprosthesis Type I. Cornea. 2016 Jul; 35(7):1008-14. PMID: 27191670; PMCID: PMC4899168 [Available on 07/01/17].
    View in: PubMed, PubMed Central
  46. Ramke M, Zhou X, Materne EC, Rajaiya J, Chodosh J. Resident corneal c-fms(+) macrophages and dendritic cells mediate early cellular infiltration in adenovirus keratitis. Exp Eye Res. 2016 06; 147:144-147. PMID: 27185163.
    View in: PubMed
  47. Liu K, Kurien BT, Zimmerman SL, Kaufman KM, Taft DH, Kottyan LC, Lazaro S, Weaver CA, Ice JA, Adler AJ, Chodosh J, Radfar L, Rasmussen A, Stone DU, Lewis DM, Li S, Koelsch KA, Igoe A, Talsania M, Kumar J, Maier-Moore JS, Harris VM, Gopalakrishnan R, Jonsson R, Lessard JA, Lu X, Gottenberg JE, Anaya JM, Cunninghame-Graham DS, Huang AJW, Brennan MT, Hughes P, Illei GG, Miceli-Richard C, Keystone EC, Bykerk VP, Hirschfield G, Xie G, Ng WF, Nordmark G, Eriksson P, Omdal R, Rhodus NL, Rischmueller M, Rohrer M, Segal BM, Vyse TJ, Wahren-Herlenius M, Witte T, Pons-Estel B, Alarcon-Riquelme ME, Guthridge JM, James JA, Lessard CJ, Kelly JA, Thompson SD, Gaffney PM, Montgomery CG, Edberg JC, Kimberly RP, Alarcón GS, Langefeld CL, Gilkeson GS, Kamen DL, Tsao BP, McCune WJ, Salmon JE, Merrill JT, Weisman MH, Wallace DJ, Utset TO, Bottinger EP, Amos CI, Siminovitch KA, Mariette X, Sivils KL, Harley JB, Scofield RH. X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome. Arthritis Rheumatol. 2016 05; 68(5):1290-1300. PMID: 26713507; PMCID: PMC5019501 [Available on 05/01/17].
    View in: PubMed, PubMed Central
  48. Salvador-Culla B, Jeong KJ, Kolovou PE, Chiang HH, Chodosh J, Dohlman CH, Kohane DS. Titanium Coating of the Boston Keratoprosthesis. Transl Vis Sci Technol. 2016 Apr; 5(2):17. PMID: 27152247.
    View in: PubMed
  49. Zhou C, Lei F, Chodosh J, Paschalis EI. The Role of Titanium Surface Microtopography on Adhesion, Proliferation, Transformation, and Matrix Deposition of Corneal Cells. Invest Ophthalmol Vis Sci. 2016 Apr 01; 57(4):1927-38. PMID: 27092719.
    View in: PubMed
  50. Robert MC, Crnej A, Shen LQ, Papaliodis GN, Dana R, Foster CS, Chodosh J, Dohlman CH. Infliximab after Boston Keratoprosthesis in Stevens-Johnson Syndrome: An Update. Ocul Immunol Inflamm. 2017 Jun; 25(3):413-417. PMID: 27015032.
    View in: PubMed
  51. Robert MC, Frenette M, Zhou C, Yan Y, Chodosh J, Jakobiec FA, Stagner AM, Vavvas D, Dohlman CH, Paschalis EI. A Drug Delivery System for Administration of Anti-TNF-a Antibody. Transl Vis Sci Technol. 2016 Mar; 5(2):11. PMID: 26981333.
    View in: PubMed
  52. Kohanim S, Palioura S, Saeed HN, Akpek EK, Amescua G, Basu S, Blomquist PH, Bouchard CS, Dart JK, Gai X, Gomes JA, Gregory DG, Iyer G, Jacobs DS, Johnson AJ, Kinoshita S, Mantagos IS, Mehta JS, Perez VL, Pflugfelder SC, Sangwan VS, Sippel KC, Sotozono C, Srinivasan B, Tan DT, Tandon R, Tseng SC, Ueta M, Chodosh J. Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis - A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease. Ocul Surf. 2016 04; 14(2):168-88. PMID: 26882981.
    View in: PubMed
  53. Menon BB, Zhou X, Spurr-Michaud S, Rajaiya J, Chodosh J, Gipson IK. Epidemic Keratoconjunctivitis-Causing Adenoviruses Induce MUC16 Ectodomain Release To Infect Ocular Surface Epithelial Cells. mSphere. 2016 Jan-Feb; 1(1). PMID: 27303700; PMCID: PMC4863608.
    View in: PubMed, PubMed Central
  54. Jain R, Sharma N, Basu S, Iyer G, Ueta M, Sotozono C, Kannabiran C, Rathi VM, Gupta N, Kinoshita S, Gomes JA, Chodosh J, Sangwan VS. Stevens-Johnson syndrome: The role of an ophthalmologist. Surv Ophthalmol. 2016 Jul-Aug; 61(4):369-99. PMID: 26829569.
    View in: PubMed
  55. Vazirani J, Ali MH, Sharma N, Gupta N, Mittal V, Atallah M, Amescua G, Chowdhury T, Abdala-Figuerola A, Ramirez-Miranda A, Navas A, Graue-Hernández EO, Chodosh J. Autologous simple limbal epithelial transplantation for unilateral limbal stem cell deficiency: multicentre results. Br J Ophthalmol. 2016 Oct; 100(10):1416-20. PMID: 26817481.
    View in: PubMed
  56. Le HG, Saeed H, Mantagos IS, Mitchell CM, Goverman J, Chodosh J. Burn unit care of Stevens Johnson syndrome/toxic epidermal necrolysis: A survey. Burns. 2016 Jun; 42(4):830-5. PMID: 26810444.
    View in: PubMed
  57. Chang VS, Chodosh J, Papaliodis GN. Chronic Ocular Complications of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: The Role of Systemic Immunomodulatory Therapy. Semin Ophthalmol. 2016; 31(1-2):178-87. PMID: 26959145.
    View in: PubMed
  58. Saeed HN, Chodosh J. Immunologic Mediators in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. Semin Ophthalmol. 2016; 31(1-2):85-90. PMID: 26959133.
    View in: PubMed
  59. Khan-Farooqi H, Chodosh J. Autologous Limbal Stem Cell Transplantation: The Progression of Diagnosis and Treatment. Semin Ophthalmol. 2016; 31(1-2):91-8. PMID: 26959134.
    View in: PubMed
  60. Jardeleza MS, Rheaume MA, Chodosh J, Lane AM, Dohlman CH. Retinal detachments after Boston Keratoprosthesis: incidence, predisposing factors, and visual outcomes. Digit J Ophthalmol. 2015; 21(4):1-15. PMID: 27330474; PMCID: PMC4902639.
    View in: PubMed, PubMed Central
  61. White ML, Chodosh J, Jang J, Dohlman C. Incidence of Stevens-Johnson Syndrome and Chemical Burns to the Eye. Cornea. 2015 Dec; 34(12):1527-33. PMID: 26488629.
    View in: PubMed
  62. Kohanim S, Palioura S, Saeed HN, Akpek EK, Amescua G, Basu S, Blomquist PH, Bouchard CS, Dart JK, Gai X, Gomes JA, Gregory DG, Iyer G, Jacobs DS, Johnson AJ, Kinoshita S, Mantagos IS, Mehta JS, Perez VL, Pflugfelder SC, Sangwan VS, Sippel KC, Sotozono C, Srinivasan B, Tan DT, Tandon R, Tseng SC, Ueta M, Chodosh J. Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis--A Comprehensive Review and Guide to Therapy. I. Systemic Disease. Ocul Surf. 2016 Jan; 14(1):2-19. PMID: 26549248.
    View in: PubMed
  63. Grassi CM, Cruzat A, Taniguchi EV, Crnej A, Colby KA, Dohlman CH, Chodosh J. Periprosthetic Tissue Loss in Patients With Idiopathic Vitreous Inflammation After the Boston Keratoprosthesis. Cornea. 2015 Nov; 34(11):1378-82. PMID: 26226472.
    View in: PubMed
  64. Al-Moujahed A, Chodosh J. Outcomes of an algorithmic approach to treating mild ocular alkali burns. JAMA Ophthalmol. 2015 Oct; 133(10):1214-6. PMID: 26226389.
    View in: PubMed
  65. Ma KN, Thanos A, Chodosh J, Shah AS, Mantagos IS. A Novel Technique for Amniotic Membrane Transplantation in Patients with Acute Stevens-Johnson Syndrome. Ocul Surf. 2016 Jan; 14(1):31-6. PMID: 26387869.
    View in: PubMed
  66. Singh G, Zhou X, Lee JY, Yousuf MA, Ramke M, Ismail AM, Lee JS, Robinson CM, Seto D, Dyer DW, Jones MS, Rajaiya J, Chodosh J. Recombination of the epsilon determinant and corneal tropism: Human adenovirus species D types 15, 29, 56, and 69. Virology. 2015 Nov; 485:452-9. PMID: 26343864; PMCID: PMC4619159 [Available on 11/01/16].
    View in: PubMed, PubMed Central
  67. Kammerdiener LL, Speiser JL, Aquavella JV, Harissi-Dagher M, Dohlman CH, Chodosh J, Ciolino JB. Protective effect of soft contact lenses after Boston keratoprosthesis. Br J Ophthalmol. 2016 Apr; 100(4):549-52. PMID: 26276169.
    View in: PubMed
  68. Müller RT, Abedi F, Cruzat A, Witkin D, Baniasadi N, Cavalcanti BM, Jamali A, Chodosh J, Dana R, Pavan-Langston D, Hamrah P. Degeneration and Regeneration of Subbasal Corneal Nerves after Infectious Keratitis: A Longitudinal In Vivo Confocal Microscopy Study. Ophthalmology. 2015 Nov; 122(11):2200-9. PMID: 26256833; PMCID: PMC4623997 [Available on 11/01/16].
    View in: PubMed, PubMed Central
  69. Davies EC, Pavan-Langston D, Chodosh J. Herpes zoster ophthalmicus: declining age at presentation. Br J Ophthalmol. 2016 Mar; 100(3):312-4. PMID: 26178905.
    View in: PubMed
  70. Rajaiya J, Zhou X, Barequet I, Gilmore MS, Chodosh J. Novel model of innate immunity in corneal infection. In Vitro Cell Dev Biol Anim. 2015 Sep; 51(8):827-34. PMID: 25977076.
    View in: PubMed
  71. Saeed H, Mantagos IS, Chodosh J. Complications of Stevens-Johnson syndrome beyond the eye and skin. Burns. 2016 Feb; 42(1):20-27. PMID: 25865527.
    View in: PubMed
  72. Stefater JA, Borkar DS, Chodosh J. Pink hypopyon in a patient with Serratia marcescens corneal ulceration. J Ophthalmic Inflamm Infect. 2015; 5:9. PMID: 25861400; PMCID: PMC4385303.
    View in: PubMed, PubMed Central
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  162. Chintakuntlawar AV, Astley R, Chodosh J. Adenovirus type 37 keratitis in the C57BL/6J mouse. Invest Ophthalmol Vis Sci. 2007 Feb; 48(2):781-8. PMID: 17251478.
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  163. Callegan MC, Cochran DC, Kane ST, Ramadan RT, Chodosh J, McLean C, Stroman DW. Virulence factor profiles and antimicrobial susceptibilities of ocular bacillus isolates. Curr Eye Res. 2006 Sep; 31(9):693-702. PMID: 16966141.
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  164. Butt AL, Chodosh J. Adenoviral keratoconjunctivitis in a tertiary care eye clinic. Cornea. 2006 Feb; 25(2):199-202. PMID: 16371782.
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  165. Chodosh J. Human adenovirus type 37 and the BALB/c mouse: progress toward a restricted adenovirus keratitis model (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc. 2006; 104:346-65. PMID: 17471351; PMCID: PMC1809897.
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  166. McDermott AM, Perez V, Huang AJ, Pflugfelder SC, Stern ME, Baudouin C, Beuerman RW, Burns AR, Calder VL, Calonge M, Chodosh J, Coster DJ, Dana R, Hazlett LD, Jones DB, Kim SK, Knop E, Li DQ, Mitchell BM, Niederkorn JY, Pearlman E, Wilhelmus KR, Kurie E. Pathways of corneal and ocular surface inflammation: a perspective from the cullen symposium. Ocul Surf. 2005 Oct; 3(4 Suppl):S131-8. PMID: 17216102.
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  167. Xiao J, Chodosh J. JNK regulates MCP-1 expression in adenovirus type 19-infected human corneal fibroblasts. Invest Ophthalmol Vis Sci. 2005 Oct; 46(10):3777-82. PMID: 16186362.
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  168. Rajala MS, Rajala RV, Astley RA, Butt AL, Chodosh J. Corneal cell survival in adenovirus type 19 infection requires phosphoinositide 3-kinase/Akt activation. J Virol. 2005 Oct; 79(19):12332-41. PMID: 16160160; PMCID: PMC1211526.
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  169. Nour M, Chodosh J. Chemokine signaling pathways in corneal fibroblasts. Ocul Surf. 2005 Oct; 3(4 Suppl):S149-51. PMID: 17216106.
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  170. Xiao J, Natarajan K, Nataraja K, Rajala MS, Astley RA, Ramadan RT, Chodosh J. Vitronectin: a possible determinant of adenovirus type 19 tropism for human corneal epithelium. Am J Ophthalmol. 2005 Sep; 140(3):363-9. PMID: 16084788.
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  171. Stone DU, Chodosh J. Epibulbar nodular fasciitis associated with floppy eyelids. Cornea. 2005 Apr; 24(3):361-2. PMID: 15778617.
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  172. Stone DU, Butt AL, Chodosh J. Ocular surface squamous neoplasia: a standard of care survey. Cornea. 2005 Apr; 24(3):297-300. PMID: 15778602.
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  173. Astley RA, Chodosh J. Selective uptake of iron oxide by rabbit conjunctival lymphoid follicles. Cornea. 2005 Apr; 24(3):334-6. PMID: 15778608.
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  174. Pereira HA, Ruan X, Gonzalez ML, Tsyshevskaya-Hoover I, Chodosh J. Modulation of corneal epithelial cell functions by the neutrophil-derived inflammatory mediator CAP37. Invest Ophthalmol Vis Sci. 2004 Dec; 45(12):4284-92. PMID: 15557434.
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  175. Stone DU, Chodosh J. Ocular rosacea: an update on pathogenesis and therapy. Curr Opin Ophthalmol. 2004 Dec; 15(6):499-502. PMID: 15523195.
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  176. Pflugfelder SC, Maskin SL, Anderson B, Chodosh J, Holland EJ, De Paiva CS, Bartels SP, Micuda T, Proskin HM, Vogel R. A randomized, double-masked, placebo-controlled, multicenter comparison of loteprednol etabonate ophthalmic suspension, 0.5%, and placebo for treatment of keratoconjunctivitis sicca in patients with delayed tear clearance. Am J Ophthalmol. 2004 Sep; 138(3):444-57. PMID: 15364229.
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  177. Chodosh J, Burris RD. Images in clinical medicine. Ocular melanocytosis. N Engl J Med. 2004 Feb 19; 350(8):809. PMID: 14973212.
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  178. Stone DU, Chodosh J. Oral tetracyclines for ocular rosacea: an evidence-based review of the literature. Cornea. 2004 Jan; 23(1):106-9. PMID: 14701969.
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  179. Nazir SA, Murphy S, Siatkowski RM, Chodosh J, Siatkowski RL. Ocular rosacea in childhood. Am J Ophthalmol. 2004 Jan; 137(1):138-44. PMID: 14700657.
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  180. Carr DJ, Chodosh J, Ash J, Lane TE. Effect of anti-CXCL10 monoclonal antibody on herpes simplex virus type 1 keratitis and retinal infection. J Virol. 2003 Sep; 77(18):10037-46. PMID: 12941914; PMCID: PMC224594.
    View in: PubMed, PubMed Central
  181. Natarajan K, Rajala MS, Chodosh J. Corneal IL-8 expression following adenovirus infection is mediated by c-Src activation in human corneal fibroblasts. J Immunol. 2003 Jun 15; 170(12):6234-43. PMID: 12794155.
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  182. Astley RA, Kennedy RC, Chodosh J. Structural and cellular architecture of conjunctival lymphoid follicles in the baboon (Papio anubis). Exp Eye Res. 2003 Jun; 76(6):685-94. PMID: 12742351.
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  183. Hampton DE, Adesina A, Chodosh J. Conjunctival sporotrichosis in the absence of antecedent trauma. Cornea. 2002 Nov; 21(8):831-3. PMID: 12410047.
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  184. Natarajan K, Ghalayini AJ, Sterling RS, Holbrook RM, Kennedy RC, Chodosh J. Activation of focal adhesion kinase in adenovirus-infected human corneal fibroblasts. Invest Ophthalmol Vis Sci. 2002 Aug; 43(8):2685-90. PMID: 12147603.
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  185. Fortney AC, Chodosh J. Conjunctival ulceration in recurrent Wegener granulomatosis. Cornea. 2002 Aug; 21(6):623-4. PMID: 12131047.
    View in: PubMed
  186. Ruan X, Chodosh J, Callegan MC, Booth MC, Lee TD, Kumar P, Gilmore MS, Pereira HA. Corneal expression of the inflammatory mediator CAP37. Invest Ophthalmol Vis Sci. 2002 May; 43(5):1414-21. PMID: 11980855.
    View in: PubMed
  187. Chodosh J, Kennedy RC. The conjunctival lymphoid follicle in mucosal immunology. DNA Cell Biol. 2002 May-Jun; 21(5-6):421-33. PMID: 12167245.
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  188. Natarajan K, Chodosh J, Kennedy R. Innate immunity in th e cornea: a putative role for keratocytes in the chemokine response to viral infection of the human corneal stroma. Adv Exp Med Biol. 2002; 506(Pt B):745-51. PMID: 12613987.
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  189. Tu EY, Culbertson WW, Pflugfelder SC, Huang A, Chodosh JC. Therapy of nonnecrotizing anterior scleritis with subconjunctival corticosteroid injection. Ophthalmology. 1995 May; 102(5):718-24. PMID: 7777270.
    View in: PubMed
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©2018 President and Fellows of Harvard College
Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.