Harvard Catalyst Profiles

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Jinjun Shi, Ph.D.

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Biography
2011
NIH Pathway to Independence Award (K99/R00)
2013
Movember-PCF Challenge Award
2014
PCF Young Investigator Award
2018
DoD LCRP Concept Award
2019
DoD PRCRP Idea Award with Special Focus
2019
ALA Lung Cancer Discovery Award
2021
Elected Fellow of the AIMBE
2021
MGB Innovation Discovery Award
2022
Clarivate Highly Cited Researcher
2023
DoD PRCRP Impact Award
2023
Clarivate Highly Cited Researcher

Overview
Our laboratory has a broad interest in nanomedicine, biomaterials, RNA therapy, immunotherapy, and antioxidative therapy for transformative biomedical applications. We are currently working on i) RNAi delivery for gene silencing; ii) mRNA delivery for protein replacement; iii) nanoparticle-mediated immune modulation; and iv) development of stimuli-responsive nanomaterials and bioinspired antioxidative polymers.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R33HL168751 (SHI, JINJUN) Jun 15, 2023 - May 31, 2025
    NIH
    A New Lipid Nanoparticle Technology Enabling Long-acting mRNA Therapy
    Role: Principal Investigator
  2. R01HL159012 (SHI, JINJUN) Jul 1, 2021 - Jun 30, 2025
    NIH
    Long-Acting RNAi Therapy for Atherosclerosis and Insulin Resistance
    Role: Principal Investigator
  3. R01HL156362 (CHEN, HONG ;SHI, JINJUN ;SRIVASTAVA, SANJAY) Dec 15, 2020 - Nov 30, 2024
    NIH
    The role of signaling adaptor protein epsin in atherosclerosis
    Role: Co-Principal Investigator
  4. R01HL127464 (TABAS, IRA A) Jan 1, 2016 - Dec 31, 2020
    NIH
    Enhancing Inflammation Resolution in Atherosclerosis via Targeted Nanoparticle-Mediated Delivery of Biologics
    Role: Co-Principal Investigator
  5. R01CA200900 (SHI, JINJUN) Dec 21, 2015 - Jun 30, 2026
    NIH
    Systemic RNA Delivery to Tumors
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.