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Mathias Lichterfeld, Ph.D., M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K24AI155233 (LICHTERFELD, MATHIAS) Jul 13, 2021 - Jun 30, 2026
    Mentoring in patient-oriented research to finding a cure for HIV-1 infection
    Role: Principal Investigator
  2. R01AI152979 (LICHTERFELD, MATHIAS) Sep 23, 2020 - Aug 31, 2025
    Selection and Evolution of HIV-1 reservoir cells in blood and tissues
    Role: Principal Investigator
  3. R01DK120387 (YUKL, STEVEN A) Jun 1, 2019 - Apr 30, 2024
    Novel single genome approaches to determine the mechanisms of HIV latent infection in blood, gut, and lymph nodes
    Role: Co-Principal Investigator
  4. R61DA047034 (YU, XU) Aug 15, 2018 - May 31, 2021
    Molecular profile of proviral reservoirs in HIV-infected drug users
    Role: Co-Principal Investigator
  5. U01AI135940 (SHAPIRO, ROGER L) Feb 20, 2018 - Jan 31, 2023
    A clinical trial to evaluate the impact of broadly neutralizing antibody VRC01 on HIV viral reservoir and maintenance of suppression in a cohort of early-treated children in Botswana
    Role: Co-Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lichterfeld M, Gao C, Yu XG. An ordeal that does not heal: understanding barriers to a cure for HIV-1 infection. Trends Immunol. 2022 Aug; 43(8):608-616. PMID: 35905706; PMCID: PMC9346997.
    Citations:    Fields:    
  2. Hartana CA, Garcia-Broncano P, Rassadkina Y, Lian X, Jiang C, Einkauf KB, Maswabi K, Ajibola G, Moyo S, Mohammed T, Maphorisa C, Makhema J, Yuki Y, Martin M, Bennett K, Jean-Philippe P, Viard M, Hughes MD, Powis KM, Carrington M, Lockman S, Gao C, Yu XG, Kuritzkes DR, Shapiro R, Lichterfeld M. Immune correlates of HIV-1 reservoir cell decline in early-treated infants. Cell Rep. 2022 Jul 19; 40(3):111126. PMID: 35858580; PMCID: PMC9314543.
    Citations:    Fields:    Translation:HumansCells
  3. Kaneko N, Boucau J, Kuo HH, Perugino C, Mahajan VS, Farmer JR, Liu H, Diefenbach TJ, Piechocka-Trocha A, Lefteri K, Waring MT, Premo KR, Walker BD, Li JZ, Gaiha G, Yu XG, Lichterfeld M, Padera RF, Pillai S. Temporal changes in T cell subsets and expansion of cytotoxic CD4+ T cells in the lungs in severe COVID-19. Clin Immunol. 2022 04; 237:108991. PMID: 35364330; PMCID: PMC8961941.
    Citations: 3     Fields:    Translation:HumansCells
  4. Francis JM, Leistritz-Edwards D, Dunn A, Tarr C, Lehman J, Dempsey C, Hamel A, Rayon V, Liu G, Wang Y, Wille M, Durkin M, Hadley K, Sheena A, Roscoe B, Ng M, Rockwell G, Manto M, Gienger E, Nickerson J, Moarefi A, Noble M, Malia T, Bardwell PD, Gordon W, Swain J, Skoberne M, Sauer K, Harris T, Goldrath AW, Shalek AK, Coyle AJ, Benoist C, Pregibon DC. Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2. Sci Immunol. 2022 01 21; 7(67):eabk3070. PMID: 34793243; PMCID: PMC9017864.
    Citations: 10     Fields:    Translation:HumansCells
  5. Einkauf KB, Osborn MR, Gao C, Sun W, Sun X, Lian X, Parsons EM, Gladkov GT, Seiger KW, Blackmer JE, Jiang C, Yukl SA, Rosenberg ES, Yu XG, Lichterfeld M. Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses. Cell. 2022 01 20; 185(2):266-282.e15. PMID: 35026153; PMCID: PMC8809251.
    Citations: 13     Fields:    Translation:HumansCells
  6. Lee GQ, Lichterfeld M. Near-Full-Length Single-Genome HIV-1 DNA Sequencing. Methods Mol Biol. 2022; 2407:357-364. PMID: 34985675; PMCID: PMC9135474.
    Citations:    Fields:    Translation:HumansCells
  7. Lian X, Gao C, Sun X, Jiang C, Einkauf KB, Seiger KW, Chevalier JM, Yuki Y, Martin M, Hoh R, Peluso MJ, Carrington M, Ruiz-Mateos E, Deeks SG, Rosenberg ES, Walker BD, Lichterfeld M, Yu XG. Signatures of immune selection in intact and defective proviruses distinguish HIV-1 elite controllers. Sci Transl Med. 2021 12 15; 13(624):eabl4097. PMID: 34910552; PMCID: PMC9202005.
    Citations: 3     Fields:    Translation:HumansCells
  8. Moraka NO, Garcia-Broncano P, Hu Z, Ajibola G, Bareng OT, Pretorius-Holme M, Maswabi K, Maphorisa C, Mohammed T, Gaseitsiwe S, VanZyl GU, Kuritzkes DR, Lichterfeld M, Moyo S, Shapiro RL. Patterns of pretreatment drug resistance mutations of very early diagnosed and treated infants in Botswana. AIDS. 2021 12 01; 35(15):2413-2421. PMID: 34324451; PMCID: PMC8631156.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  9. Cummins NW, Baker J, Chakraborty R, Dean PG, Garcia-Rivera E, Krogman A, Kumar S, Kuzmichev YV, Laird GM, Landay A, Lichterfeld M, Mahmood M, Martinson J, Maynes M, Natesampillai S, Rajkumar V, Rassadkina Y, Ritter KD, Rivera CG, Rizza SA, Subramanian K, Tande AJ, Wonderlich ER, Whitaker JA, Zeuli J, Badley AD. Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo. EClinicalMedicine. 2021 Dec; 42:101225. PMID: 34901797; PMCID: PMC8639424.
  10. Turk G, Seiger K, Lian X, Sun W, Parsons EM, Gao C, Rassadkina Y, Polo ML, Czernikier A, Ghiglione Y, Vellicce A, Varriale J, Lai J, Yuki Y, Martin M, Rhodes A, Lewin SR, Walker BD, Carrington M, Siliciano R, Siliciano J, Lichterfeld M, Laufer N, Yu XG. A Possible Sterilizing Cure of HIV-1 Infection Without Stem Cell Transplantation. Ann Intern Med. 2022 01; 175(1):95-100. PMID: 34781719; PMCID: PMC9215120.
    Citations: 7     Fields:    Translation:HumansCells
  11. Collins DR, Urbach JM, Racenet ZJ, Arshad U, Power KA, Newman RM, Mylvaganam GH, Ly NL, Lian X, Rull A, Rassadkina Y, Yanez AG, Peluso MJ, Deeks SG, Vidal F, Lichterfeld M, Yu XG, Gaiha GD, Allen TM, Walker BD. Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia. Immunity. 2021 10 12; 54(10):2372-2384.e7. PMID: 34496223; PMCID: PMC8516715.
    Citations: 3     Fields:    Translation:HumansCells
  12. Ajibola G, Garcia-Broncano P, Maswabi K, Bennett K, Hughes MD, Moyo S, Mohammed T, Jean-Philippe P, Sakoi M, Batlang O, Lockman S, Makhema J, Kuritzkes DR, Lichterfeld M, Shapiro RL. Viral Reservoir in Early-Treated Human Immunodeficiency Virus-Infected Children and Markers for Sustained Viral Suppression. Clin Infect Dis. 2021 08 16; 73(4):e997-e1003. PMID: 33605999; PMCID: PMC8366827.
    Citations: 3     Fields:    Translation:HumansCells
  13. Li Y, Etemad B, Dele-Oni R, Sharaf R, Gao C, Lichterfeld M, Li JZ. Drug resistance mutations in HIV provirus are associated with defective proviral genomes with hypermutation. AIDS. 2021 06 01; 35(7):1015-1020. PMID: 33635848; PMCID: PMC8102365.
    Citations:    Fields:    Translation:HumansCells
  14. Hartana CA, Rassadkina Y, Gao C, Martin-Gayo E, Walker BD, Lichterfeld M, Yu XG. Long noncoding RNA MIR4435-2HG enhances metabolic function of myeloid dendritic cells from HIV-1 elite controllers. J Clin Invest. 2021 05 03; 131(9). PMID: 33938445; PMCID: PMC8087208.
    Citations: 5     Fields:    Translation:HumansCells
  15. Kaneko N, Boucau J, Kuo HH, Perugino C, Mahajan VS, Farmer JR, Liu H, Diefenbach TJ, Piechocka-Trocha A, Lefteri K, Waring MT, Premo KR, Walker BD, Li JZ, Gaiha G, Yu XG, Lichterfeld M, Padera RF, Pillai S. Expansion of Cytotoxic CD4+ T cells in the lungs in severe COVID-19. medRxiv. 2021 Mar 26. PMID: 33791730; PMCID: PMC8010762.
  16. Maswabi K, Ajibola G, Bennett K, Capparelli EV, Jean-Philippe P, Moyo S, Mohammed T, Batlang O, Sakoi M, Lockman S, Makhema J, Lichterfeld M, Kuritzkes DR, Hughes MD, Shapiro RL. Safety and Efficacy of Starting Antiretroviral Therapy in the First Week of Life. Clin Infect Dis. 2021 02 01; 72(3):388-393. PMID: 31927562.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  17. Offersen R, Yu WH, Scully EP, Julg B, Euler Z, Sadanand S, Garcia-Dominguez D, Zheng L, Rasmussen TA, Jennewein MF, Linde C, Sassic J, Lofano G, Vigano S, Stephenson KE, Fischinger S, Suscovich TJ, Lichterfeld M, Lauffenburger D, Rosenberg ES, Allen T, Altfeld M, Charles RC, Østergaard L, Tolstrup M, Barouch DH, Søgaard OS, Alter G. HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound. Cell Rep. 2020 12 15; 33(11):108502. PMID: 33326789.
    Citations: 5     Fields:    Translation:HumansCells
  18. Choi B, Choudhary MC, Regan J, Sparks JA, Padera RF, Qiu X, Solomon IH, Kuo HH, Boucau J, Bowman K, Adhikari UD, Winkler ML, Mueller AA, Hsu TY, Desjardins M, Baden LR, Chan BT, Walker BD, Lichterfeld M, Brigl M, Kwon DS, Kanjilal S, Richardson ET, Jonsson AH, Alter G, Barczak AK, Hanage WP, Yu XG, Gaiha GD, Seaman MS, Cernadas M, Li JZ. Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host. N Engl J Med. 2020 12 03; 383(23):2291-2293. PMID: 33176080; PMCID: PMC7673303.
    Citations: 363     Fields:    Translation:HumansCells
  19. Abdel-Mohsen M, Richman D, Siliciano RF, Nussenzweig MC, Howell BJ, Martinez-Picado J, Chomont N, Bar KJ, Yu XG, Lichterfeld M, Alcami J, Hazuda D, Bushman F, Siliciano JD, Betts MR, Spivak AM, Planelles V, Hahn BH, Smith DM, Ho YC, Buzon MJ, Gaebler C, Paiardini M, Li Q, Estes JD, Hope TJ, Kostman J, Mounzer K, Caskey M, Fox L, Frank I, Riley JL, Tebas P, Montaner LJ. Recommendations for measuring HIV reservoir size in cure-directed clinical trials. Nat Med. 2020 09; 26(9):1339-1350. PMID: 32895573; PMCID: PMC7703694.
    Citations: 39     Fields:    Translation:HumansCellsPHPublic Health
  20. Jiang C, Lian X, Gao C, Sun X, Einkauf KB, Chevalier JM, Chen SMY, Hua S, Rhee B, Chang K, Blackmer JE, Osborn M, Peluso MJ, Hoh R, Somsouk M, Milush J, Bertagnolli LN, Sweet SE, Varriale JA, Burbelo PD, Chun TW, Laird GM, Serrao E, Engelman AN, Carrington M, Siliciano RF, Siliciano JM, Deeks SG, Walker BD, Lichterfeld M, Yu XG. Distinct viral reservoirs in individuals with spontaneous control of HIV-1. Nature. 2020 09; 585(7824):261-267. PMID: 32848246; PMCID: PMC7837306.
    Citations: 83     Fields:    Translation:HumansCells
  21. Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Alter G, Li JZ, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu XG, Padera RF, Pillai S. Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19. Cell. 2020 10 01; 183(1):143-157.e13. PMID: 32877699; PMCID: PMC7437499.
    Citations: 253     Fields:    Translation:HumansCellsPHPublic Health
  22. Kuo HH, Banga R, Lee GQ, Gao C, Cavassini M, Corpataux JM, Blackmer JE, Zur Wiesch S, Yu XG, Pantaleo G, Perreau M, Lichterfeld M. Blood and Lymph Node Dissemination of Clonal Genome-Intact Human Immunodeficiency Virus 1 DNA Sequences During Suppressive Antiretroviral Therapy. J Infect Dis. 2020 07 23; 222(4):655-660. PMID: 32236405; PMCID: PMC8493664.
    Citations: 5     Fields:    Translation:HumansCells
  23. Davey S, Ajibola G, Maswabi K, Sakoi M, Bennett K, Hughes MD, Isaacson A, Diseko M, Zash R, Batlang O, Moyo S, Lockman S, Lichterfeld M, Kuritzkes DR, Makhema J, Shapiro R. Mother-to-Child HIV Transmission With In Utero Dolutegravir vs. Efavirenz in Botswana. J Acquir Immune Defic Syndr. 2020 07 01; 84(3):235-241. PMID: 32195745; PMCID: PMC7293566.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  24. Ajibola G, Moyo S, Mohammed T, Moseki S, Jack D, Sakoi M, Batlang O, Maswabi K, Bennett K, Hughes MD, Lockman S, Makhema JM, Lichterfeld M, Kuritzkes DR, Shapiro RL. HIV diagnostic algorithm requires confirmatory testing for initial indeterminate or positive screens in the first week of life. AIDS. 2020 06 01; 34(7):1029-1035. PMID: 32287064; PMCID: PMC7773540.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  25. Sun X, Hua S, Gao C, Blackmer JE, Ouyang Z, Ard K, Ciaranello A, Yawetz S, Sax PE, Rosenberg ES, Lichterfeld M, Yu XG. Immune-profiling of ZIKV-infected patients identifies a distinct function of plasmacytoid dendritic cells for immune cross-regulation. Nat Commun. 2020 05 15; 11(1):2421. PMID: 32415086.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  26. Li JZ, Segal FP, Bosch RJ, Lalama CM, Roberts-Toler C, Delagreverie H, Getz R, Garcia-Broncano P, Kinslow J, Tressler R, Van Dam CN, Keefer M, Carrington M, Lichterfeld M, Kuritzkes D, Yu XG, Landay A, Sax PE. Antiretroviral Therapy Reduces T-cell Activation and Immune Exhaustion Markers in Human Immunodeficiency Virus Controllers. Clin Infect Dis. 2020 04 10; 70(8):1636-1642. PMID: 31131858; PMCID: PMC7146008.
    Citations: 14     Fields:    Translation:HumansCellsCTClinical Trials
  27. Lichterfeld M. Reactivation of latent HIV moves shock-and-kill treatments forward. Nature. 2020 02; 578(7793):42-43. PMID: 32020104.
    Citations: 7     Fields:    Translation:HumansCells
  28. Martin-Gayo E, Gao C, Chen HR, Ouyang Z, Kim D, Kolb KE, Shalek AK, Walker BD, Lichterfeld M, Yu XG. Immunological Fingerprints of Controllers Developing Neutralizing HIV-1 Antibodies. Cell Rep. 2020 01 28; 30(4):984-996.e4. PMID: 31995767; PMCID: PMC6990401.
    Citations: 10     Fields:    Translation:HumansCells
  29. Mavigner M, Zanoni M, Tharp GK, Habib J, Mattingly CR, Lichterfeld M, Nega MT, Vanderford TH, Bosinger SE, Chahroudi A. Pharmacological Modulation of the Wnt/ß-Catenin Pathway Inhibits Proliferation and Promotes Differentiation of Long-Lived Memory CD4+ T Cells in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques. J Virol. 2019 12 12; 94(1). PMID: 31619550; PMCID: PMC6912121.
    Citations: 6     Fields:    Translation:AnimalsCells
  30. Garcia-Broncano P, Maddali S, Einkauf KB, Jiang C, Gao C, Chevalier J, Chowdhury FZ, Maswabi K, Ajibola G, Moyo S, Mohammed T, Ncube T, Makhema J, Jean-Philippe P, Yu XG, Powis KM, Lockman S, Kuritzkes DR, Shapiro R, Lichterfeld M. Early antiretroviral therapy in neonates with HIV-1 infection restricts viral reservoir size and induces a distinct innate immune profile. Sci Transl Med. 2019 11 27; 11(520). PMID: 31776292; PMCID: PMC8397898.
    Citations: 36     Fields:    Translation:HumansCells
  31. Vibholm LK, Konrad CV, Schleimann MH, Frattari G, Winckelmann A, Klastrup V, Jensen NM, Jensen SS, Schmidt M, Wittig B, Zuwala K, Mack K, Olesen R, Hua S, Lichterfeld M, Østergaard L, Denton PW, Tolstrup M, Søgaard OS. Effects of 24-week Toll-like receptor 9 agonist treatment in HIV type 1+ individuals. AIDS. 2019 07 01; 33(8):1315-1325. PMID: 30932955.
    Citations: 29     Fields:    Translation:HumansCellsCTClinical Trials
  32. Lee GQ, Reddy K, Einkauf KB, Gounder K, Chevalier JM, Dong KL, Walker BD, Yu XG, Ndung'u T, Lichterfeld M. HIV-1 DNA sequence diversity and evolution during acute subtype C infection. Nat Commun. 2019 06 21; 10(1):2737. PMID: 31227699.
    Citations: 27     Fields:    Translation:HumansCells
  33. Einkauf KB, Lee GQ, Gao C, Sharaf R, Sun X, Hua S, Chen SM, Jiang C, Lian X, Chowdhury FZ, Rosenberg ES, Chun TW, Li JZ, Yu XG, Lichterfeld M. Intact HIV-1 proviruses accumulate at distinct chromosomal positions during prolonged antiretroviral therapy. J Clin Invest. 2019 03 01; 129(3):988-998. PMID: 30688658; PMCID: PMC6391088.
    Citations: 102     Fields:    Translation:HumansCellsCTClinical Trials
  34. Chowdhury FZ, Ouyang Z, Buzon M, Walker BD, Lichterfeld M, Yu XG. Metabolic pathway activation distinguishes transcriptional signatures of CD8+ T cells from HIV-1 elite controllers. AIDS. 2018 11 28; 32(18):2669-2677. PMID: 30289807; PMCID: PMC6317861.
    Citations: 15     Fields:    Translation:HumansCells
  35. Sharaf R, Lee GQ, Sun X, Etemad B, Aboukhater LM, Hu Z, Brumme ZL, Aga E, Bosch RJ, Wen Y, Namazi G, Gao C, Acosta EP, Gandhi RT, Jacobson JM, Skiest D, Margolis DM, Mitsuyasu R, Volberding P, Connick E, Kuritzkes DR, Lederman MM, Yu XG, Lichterfeld M, Li JZ. HIV-1 proviral landscapes distinguish posttreatment controllers from noncontrollers. J Clin Invest. 2018 08 31; 128(9):4074-4085. PMID: 30024859; PMCID: PMC6118642.
    Citations: 38     Fields:    Translation:HumansCells
  36. Hua S, Vigano S, Tse S, Zhengyu O, Harrington S, Negron J, Garcia-Broncano P, Marchetti G, Genebat M, Leal M, Resino S, Ruiz-Mateos E, Lichterfeld M, Yu XG. Pegylated Interferon-a-Induced Natural Killer Cell Activation Is Associated With Human Immunodeficiency Virus-1 DNA Decline in Antiretroviral Therapy-Treated HIV-1/Hepatitis C Virus-Coinfected Patients. Clin Infect Dis. 2018 06 01; 66(12):1910-1917. PMID: 29272392.
    Citations: 19     Fields:    Translation:HumansCells
  37. Kuo HH, Ahmad R, Lee GQ, Gao C, Chen HR, Ouyang Z, Szucs MJ, Kim D, Tsibris A, Chun TW, Battivelli E, Verdin E, Rosenberg ES, Carr SA, Yu XG, Lichterfeld M. Anti-apoptotic Protein BIRC5 Maintains Survival of HIV-1-Infected CD4+ T Cells. Immunity. 2018 06 19; 48(6):1183-1194.e5. PMID: 29802019.
    Citations: 50     Fields:    Translation:HumansCells
  38. Kuo HH, Lichterfeld M. Recent progress in understanding HIV reservoirs. Curr Opin HIV AIDS. 2018 03; 13(2):137-142. PMID: 29232209; PMCID: PMC5806203.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  39. Brinkmann CR, Højen JF, Rasmussen TA, Kjær AS, Olesen R, Denton PW, Østergaard L, Ouyang Z, Lichterfeld M, Yu X, Søgaard OS, Dinarello C, Tolstrup M. Treatment of HIV-Infected Individuals with the Histone Deacetylase Inhibitor Panobinostat Results in Increased Numbers of Regulatory T Cells and Limits Ex Vivo Lipopolysaccharide-Induced Inflammatory Responses. mSphere. 2018 Jan-Feb; 3(1). PMID: 29468194.
    Citations: 7     Fields:    
  40. Martin-Gayo E, Cole MB, Kolb KE, Ouyang Z, Cronin J, Kazer SW, Ordovas-Montanes J, Lichterfeld M, Walker BD, Yosef N, Shalek AK, Yu XG. A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers. Genome Biol. 2018 01 29; 19(1):10. PMID: 29378643.
    Citations: 20     Fields:    Translation:HumansCells
  41. Clarridge KE, Blazkova J, Einkauf K, Petrone M, Refsland EW, Justement JS, Shi V, Huiting ED, Seamon CA, Lee GQ, Yu XG, Moir S, Sneller MC, Lichterfeld M, Chun TW. Effect of analytical treatment interruption and reinitiation of antiretroviral therapy on HIV reservoirs and immunologic parameters in infected individuals. PLoS Pathog. 2018 01; 14(1):e1006792. PMID: 29324842.
    Citations: 46     Fields:    Translation:HumansCells
  42. Sun X, Hua S, Chen HR, Ouyang Z, Einkauf K, Tse S, Ard K, Ciaranello A, Yawetz S, Sax P, Rosenberg ES, Lichterfeld M, Yu XG. Transcriptional Changes during Naturally Acquired Zika Virus Infection Render Dendritic Cells Highly Conducive to Viral Replication. Cell Rep. 2017 Dec 19; 21(12):3471-3482. PMID: 29262327.
    Citations: 38     Fields:    Translation:HumansCells
  43. Cummins NW, Rizza S, Litzow MR, Hua S, Lee GQ, Einkauf K, Chun TW, Rhame F, Baker JV, Busch MP, Chomont N, Dean PG, Fromentin R, Haase AT, Hampton D, Keating SM, Lada SM, Lee TH, Natesampillai S, Richman DD, Schacker TW, Wietgrefe S, Yu XG, Yao JD, Zeuli J, Lichterfeld M, Badley AD. Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study. PLoS Med. 2017 Nov; 14(11):e1002461. PMID: 29182633.
    Citations: 26     Fields:    Translation:HumansCells
  44. Orlova-Fink N, Chowdhury FZ, Sun X, Harrington S, Rosenberg ES, Yu XG, Lichterfeld M. Preferential susceptibility of Th9 and Th2 CD4+ T cells to X4-tropic HIV-1 infection. AIDS. 2017 10 23; 31(16):2211-2215. PMID: 28857825; PMCID: PMC6354239.
    Citations: 4     Fields:    Translation:HumansCells
  45. Lee GQ, Orlova-Fink N, Einkauf K, Chowdhury FZ, Sun X, Harrington S, Kuo HH, Hua S, Chen HR, Ouyang Z, Reddy K, Dong K, Ndung'u T, Walker BD, Rosenberg ES, Yu XG, Lichterfeld M. Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells. J Clin Invest. 2017 Jun 30; 127(7):2689-2696. PMID: 28628034; PMCID: PMC5490740.
    Citations: 138     Fields:    Translation:HumansCells
  46. Vibholm L, Schleimann MH, Højen JF, Benfield T, Offersen R, Rasmussen K, Olesen R, Dige A, Agnholt J, Grau J, Buzon M, Wittig B, Lichterfeld M, Petersen AM, Deng X, Abdel-Mohsen M, Pillai SK, Rutsaert S, Trypsteen W, De Spiegelaere W, Vandekerchove L, Østergaard L, Rasmussen TA, Denton PW, Tolstrup M, Søgaard OS. Short-Course Toll-Like Receptor 9 Agonist Treatment Impacts Innate Immunity and Plasma Viremia in Individuals With Human Immunodeficiency Virus Infection. Clin Infect Dis. 2017 Jun 15; 64(12):1686-1695. PMID: 28329286; PMCID: PMC5849129.
    Citations: 71     Fields:    Translation:HumansCellsCTClinical Trials
  47. Dominguez-Molina B, Tarancon-Diez L, Hua S, Abad-Molina C, Rodriguez-Gallego E, Machmach K, Vidal F, Tural C, Moreno S, Goñi MJ, Ramírez de Arellano E, Del Val M, Gonzalez-Escribano MF, Del Romero J, Rodriguez C, Capa L, Viciana P, Alcamí J, Yu XG, Walker BD, Leal M, Lichterfeld M, Ruiz-Mateos E. HLA-B*57 and IFNL4-Related Polymorphisms Are Associated With Protection Against HIV-1 Disease Progression in Controllers. Clin Infect Dis. 2017 Feb 09. PMID: 28182214.
  48. Martin-Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb KE, Schulze Zur Wiesch J, Cubas R, Porichis F, Shalek AK, van Lunzen J, Haddad EK, Walker BD, Kaufmann DE, Lichterfeld M, Yu XG. Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth. JCI Insight. 2017 01 26; 2(2):e89574. PMID: 28138558.
    Citations: 24     Fields:    Translation:HumansCells
  49. Viganò S, Negrón JJ, Tse S, Chowdhury FZ, Lichterfeld M, Yu XG. HLA-G+ HIV-1-specific CD8+ T cells are associated with HIV-1 immune control. AIDS. 2017 01 14; 31(2):207-212. PMID: 27835619; PMCID: PMC5177477.
    Citations: 3     Fields:    Translation:HumansCells
  50. Gattinoni L, Speiser DE, Lichterfeld M, Bonini C. T memory stem cells in health and disease. Nat Med. 2017 01 06; 23(1):18-27. PMID: 28060797; PMCID: PMC6354775.
    Citations: 160     Fields:    Translation:HumansAnimalsCells
  51. McGary CS, Alvarez X, Harrington S, Cervasi B, Ryan ES, Iriele RI, Paganini S, Harper JL, Easley K, Silvestri G, Ansari AA, Lichterfeld M, Micci L, Paiardini M. The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques. Mucosal Immunol. 2017 07; 10(4):1082-1096. PMID: 28051083.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  52. Dominguez-Molina B, Tarancon-Diez L, Hua S, Abad-Molina C, Rodriguez-Gallego E, Machmach K, Vidal F, Tural C, Moreno S, Goñi JM, Ramírez de Arellano E, Del Val M, Gonzalez-Escribano MF, Del Romero J, Rodriguez C, Capa L, Viciana P, Alcamí J, Yu XG, Walker BD, Leal M, Lichterfeld M, Ruiz-Mateos E. HLA-B*57 and IFNL4-related polymorphisms are associated with protection against HIV-1 disease progression in controllers. Clin Infect Dis. 2017 03 01; 64(5):621-628. PMID: 27986689; PMCID: PMC5849048.
    Citations: 18     Fields:    Translation:HumansCells
  53. Barton K, Hiener B, Winckelmann A, Rasmussen TA, Shao W, Byth K, Lanfear R, Solomon A, McMahon J, Harrington S, Buzon M, Lichterfeld M, Denton PW, Olesen R, Østergaard L, Tolstrup M, Lewin SR, Søgaard OS, Palmer S. Broad activation of latent HIV-1 in vivo. Nat Commun. 2016 09 08; 7:12731. PMID: 27605062.
    Citations: 40     Fields:    Translation:HumansCellsCTClinical Trials
  54. Paiardini M, Lichterfeld M. Follicular T helper cells: hotspots for HIV-1 persistence. Nat Med. 2016 07 07; 22(7):711-2. PMID: 27387885.
    Citations: 6     Fields:    Translation:HumansCells
  55. Lee GQ, Lichterfeld M. Diversity of HIV-1 reservoirs in CD4+ T-cell subpopulations. Curr Opin HIV AIDS. 2016 07; 11(4):383-7. PMID: 27023286; PMCID: PMC4915926.
    Citations: 33     Fields:    Translation:HumansCells
  56. Jones RB, Mueller S, O'Connor R, Rimpel K, Sloan DD, Karel D, Wong HC, Jeng EK, Thomas AS, Whitney JB, Lim SY, Kovacs C, Benko E, Karandish S, Huang SH, Buzon MJ, Lichterfeld M, Irrinki A, Murry JP, Tsai A, Yu H, Geleziunas R, Trocha A, Ostrowski MA, Irvine DJ, Walker BD. A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4+ T-Cells to Recognition by Cytotoxic T-Lymphocytes. PLoS Pathog. 2016 Apr; 12(4):e1005545. PMID: 27082643; PMCID: PMC4833318.
    Citations: 84     Fields:    Translation:HumansCells
  57. Kiselinova M, De Spiegelaere W, Buzon MJ, Malatinkova E, Lichterfeld M, Vandekerckhove L. Correction: Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth. PLoS Pathog. 2016 Mar; 12(3):e1005532. PMID: 27003005; PMCID: PMC4803328.
    Citations: 4     Fields:    
  58. Kiselinova M, De Spiegelaere W, Buzon MJ, Malatinkova E, Lichterfeld M, Vandekerckhove L. Integrated and Total HIV-1 DNA Predict Ex Vivo Viral Outgrowth. PLoS Pathog. 2016 Mar; 12(3):e1005472. PMID: 26938995; PMCID: PMC4777389.
    Citations: 53     Fields:    Translation:HumansCells
  59. Sun H, Kim D, Li X, Kiselinova M, Ouyang Z, Vandekerckhove L, Shang H, Rosenberg ES, Yu XG, Lichterfeld M. Th1/17 Polarization of CD4 T Cells Supports HIV-1 Persistence during Antiretroviral Therapy. J Virol. 2015 Nov; 89(22):11284-93. PMID: 26339043; PMCID: PMC4645661.
    Citations: 49     Fields:    Translation:HumansCells
  60. Olesen R, Vigano S, Rasmussen TA, Søgaard OS, Ouyang Z, Buzon M, Bashirova A, Carrington M, Palmer S, Brinkmann CR, Yu XG, Østergaard L, Tolstrup M, Lichterfeld M. Innate Immune Activity Correlates with CD4 T Cell-Associated HIV-1 DNA Decline during Latency-Reversing Treatment with Panobinostat. J Virol. 2015 Oct; 89(20):10176-89. PMID: 26223643; PMCID: PMC4580197.
    Citations: 50     Fields:    Translation:HumansCellsCTClinical Trials
  61. Rokx C, Richman DD, Müller-Trutwin M, Silvestri G, Lunzen J, Khoo S, Lichterfeld M, Altfeld M, Perno CF, Hunt PW, Mallon P, Rockstroh JK, Pozniak AL, Clotet B, Boucher CA. Second European Round Table on the Future Management of HIV: 10-11 October 2014, Barcelona, Spain. J Virus Erad. 2015 Jul 01; 1(3):211-20. PMID: 27482415; PMCID: PMC4946744.
  62. Martin-Gayo E, Buzon MJ, Ouyang Z, Hickman T, Cronin J, Pimenova D, Walker BD, Lichterfeld M, Yu XG. Potent Cell-Intrinsic Immune Responses in Dendritic Cells Facilitate HIV-1-Specific T Cell Immunity in HIV-1 Elite Controllers. PLoS Pathog. 2015 Jun; 11(6):e1004930. PMID: 26067651.
    Citations: 40     Fields:    Translation:HumansCells
  63. Vigano S, Negron J, Ouyang Z, Rosenberg ES, Walker BD, Lichterfeld M, Yu XG. Prolonged Antiretroviral Therapy Preserves HIV-1-Specific CD8 T Cells with Stem Cell-Like Properties. J Virol. 2015 Aug; 89(15):7829-40. PMID: 25995260.
    Citations: 23     Fields:    Translation:HumansCells
  64. Ouyang Z, Buzon MJ, Zheng L, Sun H, Yu XG, Bosch RJ, Mellors JW, Eron JJ, Gandhi RT, Lichterfeld M. Transcriptional Changes in CD8(+) T Cells During Antiretroviral Therapy Intensified With Raltegravir. Open Forum Infect Dis. 2015 Apr; 2(2):ofv045. PMID: 26380343; PMCID: PMC4567091.
    Citations: 1     
  65. Chahroudi A, Silvestri G, Lichterfeld M. T memory stem cells and HIV: a long-term relationship. Curr HIV/AIDS Rep. 2015 Mar; 12(1):33-40. PMID: 25578055.
    Citations: 32     Fields:    Translation:HumansCells
  66. Ho HP, Rathod P, Louis M, Tada CK, Rahaman S, Mark KJ, Leng J, Dana D, Kumar S, Lichterfeld M, Chang EJ. Studies on quantitative phosphopeptide analysis by matrix-assisted laser desorption/ionization mass spectrometry without label, chromatography or calibration curves. Rapid Commun Mass Spectrom. 2014 Dec 30; 28(24):2681-9. PMID: 25380489; PMCID: PMC4225566.
    Citations: 1     Fields:    Translation:Cells
  67. Gaiha GD, McKim KJ, Woods M, Pertel T, Rohrbach J, Barteneva N, Chin CR, Liu D, Soghoian DZ, Cesa K, Wilton S, Waring MT, Chicoine A, Doering T, Wherry EJ, Kaufmann DE, Lichterfeld M, Brass AL, Walker BD. Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis. Immunity. 2014 Dec 18; 41(6):1001-12. PMID: 25526311.
    Citations: 38     Fields:    Translation:HumansCells
  68. Martin-Gayo E, Hickman T, Ouyang Z, Cubas R, Lindqvist M, Kauffman D, Haddad E, Walker B, Lichterfeld M, Yu XG. Dendritic Cells from HIV-1 Neutralizers Efficiently Induce the Generation of CXCR5(+) CXCR3(+) PD1(Lo) CD4 T Cells with B Cell Helper Function. AIDS Res Hum Retroviruses. 2014 Oct; 30 Suppl 1:A74. PMID: 25357934.
  69. Rasmussen TA, Tolstrup M, Brinkmann CR, Olesen R, Erikstrup C, Solomon A, Winckelmann A, Palmer S, Dinarello C, Buzon M, Lichterfeld M, Lewin SR, Østergaard L, Søgaard OS. Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial. Lancet HIV. 2014 Oct; 1(1):e13-21. PMID: 26423811.
    Citations: 329     Fields:    
  70. Jones RB, O'Connor R, Mueller S, Foley M, Szeto GL, Karel D, Lichterfeld M, Kovacs C, Ostrowski MA, Trocha A, Irvine DJ, Walker BD. Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes. PLoS Pathog. 2014 Aug; 10(8):e1004287. PMID: 25122219.
    Citations: 124     Fields:    Translation:HumansCells
  71. Buzon MJ, Martin-Gayo E, Pereyra F, Ouyang Z, Sun H, Li JZ, Piovoso M, Shaw A, Dalmau J, Zangger N, Martinez-Picado J, Zurakowski R, Yu XG, Telenti A, Walker BD, Rosenberg ES, Lichterfeld M. Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells. J Virol. 2014 Sep 01; 88(17):10056-65. PMID: 24965451.
    Citations: 142     Fields:    Translation:HumansCells
  72. Leng J, Ho HP, Buzon MJ, Pereyra F, Walker BD, Yu XG, Chang EJ, Lichterfeld M. A cell-intrinsic inhibitor of HIV-1 reverse transcription in CD4(+) T cells from elite controllers. Cell Host Microbe. 2014 Jun 11; 15(6):717-728. PMID: 24922574.
    Citations: 28     Fields:    Translation:HumansCells
  73. Jost S, Tomezsko PJ, Rands K, Toth I, Lichterfeld M, Gandhi RT, Altfeld M. CD4+ T-cell help enhances NK cell function following therapeutic HIV-1 vaccination. J Virol. 2014 Aug; 88(15):8349-54. PMID: 24829350.
    Citations: 25     Fields:    Translation:HumansCellsPHPublic Health
  74. Bashirova AA, Martin-Gayo E, Jones DC, Qi Y, Apps R, Gao X, Burke PS, Taylor CJ, Rogich J, Wolinsky S, Bream JH, Duggal P, Hussain S, Martinson J, Weintrob A, Kirk GD, Fellay J, Buchbinder SP, Goedert JJ, Deeks SG, Pereyra F, Trowsdale J, Lichterfeld M, Telenti A, Walker BD, Allen RL, Carrington M, Yu XG. LILRB2 interaction with HLA class I correlates with control of HIV-1 infection. PLoS Genet. 2014 Mar; 10(3):e1004196. PMID: 24603468; PMCID: PMC3945438.
    Citations: 41     Fields:    Translation:HumansCells
  75. Boufassa F, Lechenadec J, Meyer L, Costagliola D, Hunt PW, Pereyra F, Deeks S, Pancino G, Taulera O, Lichterfeld M, Delobel P, Saez-Cirion A, Lambotte O. Blunted response to combination antiretroviral therapy in HIV elite controllers: an international HIV controller collaboration. PLoS One. 2014; 9(1):e85516. PMID: 24465584.
    Citations: 17     Fields:    Translation:Humans
  76. Buzon MJ, Sun H, Li C, Shaw A, Seiss K, Ouyang Z, Martin-Gayo E, Leng J, Henrich TJ, Li JZ, Pereyra F, Zurakowski R, Walker BD, Rosenberg ES, Yu XG, Lichterfeld M. HIV-1 persistence in CD4+ T cells with stem cell-like properties. Nat Med. 2014 Feb; 20(2):139-42. PMID: 24412925.
    Citations: 235     Fields:    Translation:HumansCells
  77. Buzon MJ, Yang Y, Ouyang Z, Sun H, Seiss K, Rogich J, Le Gall S, Pereyra F, Rosenberg ES, Yu XG, Lichterfeld M. Susceptibility to CD8 T-cell-mediated killing influences the reservoir of latently HIV-1-infected CD4 T cells. J Acquir Immune Defic Syndr. 2014 Jan 01; 65(1):1-9. PMID: 23846565; PMCID: PMC3874432.
    Citations: 15     Fields:    Translation:HumansCells
  78. Sun H, Buzon MJ, Shaw A, Berg RK, Yu XG, Ferrando-Martinez S, Leal M, Ruiz-Mateos E, Lichterfeld M. Hepatitis C therapy with interferon-a and ribavirin reduces CD4 T-cell-associated HIV-1 DNA in HIV-1/hepatitis C virus-coinfected patients. J Infect Dis. 2014 May 01; 209(9):1315-20. PMID: 24277743; PMCID: PMC3982848.
    Citations: 42     Fields:    Translation:HumansCells
  79. Novis CL, Archin NM, Buzon MJ, Verdin E, Round JL, Lichterfeld M, Margolis DM, Planelles V, Bosque A. Reactivation of latent HIV-1 in central memory CD4? T cells through TLR-1/2 stimulation. Retrovirology. 2013 Oct 24; 10:119. PMID: 24156240.
    Citations: 78     Fields:    Translation:HumansCells
  80. Lichterfeld M, Rosenberg ES. Acute HIV-1 infection: a call to action. Ann Intern Med. 2013 Sep 17; 159(6):425-7. PMID: 24042369.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  81. Li C, Toth I, Schulze Zur Wiesch J, Pereyra F, Rychert J, Rosenberg ES, van Lunzen J, Lichterfeld M, Yu XG. Functional characterization of HLA-G? regulatory T cells in HIV-1 infection. PLoS Pathog. 2013 Jan; 9(1):e1003140. PMID: 23382678.
    Citations: 14     Fields:    Translation:HumansCells
  82. Yang Y, Al-Mozaini M, Buzon MJ, Beamon J, Ferrando-Martinez S, Ruiz-Mateos E, Rosenberg ES, Pereyra F, Yu XG, Lichterfeld M. CD4 T-cell regeneration in HIV-1 elite controllers. AIDS. 2012 Mar 27; 26(6):701-6. PMID: 22301416; PMCID: PMC3729591.
    Citations: 18     Fields:    Translation:HumansCells
  83. Lichterfeld M, Cung T, Seiss K, Rosenberg ES, Pereyra F, Yu XG. Shelterin dysfunction and p16(INK4a)-mediated growth inhibition in HIV-1-specific CD8 T cells. J Virol. 2012 May; 86(10):5533-40. PMID: 22398292; PMCID: PMC3347267.
    Citations: 3     Fields:    Translation:HumansCells
  84. Huang J, Al-Mozaini M, Rogich J, Carrington MF, Seiss K, Pereyra F, Lichterfeld M, Yu XG. Systemic inhibition of myeloid dendritic cells by circulating HLA class I molecules in HIV-1 infection. Retrovirology. 2012 Jan 30; 9:11. PMID: 22289474.
    Citations: 7     Fields:    Translation:HumansCells
  85. Lichterfeld M, Gandhi RT, Simmons RP, Flynn T, Sbrolla A, Yu XG, Basgoz N, Mui S, Williams K, Streeck H, Burgett-Yandow N, Roy G, Janssens M, Pedneault L, Vandepapelière P, Koutsoukos M, Demoitié MA, Bourguignon P, McNally L, Voss G, Altfeld M. Induction of strong HIV-1-specific CD4+ T-cell responses using an HIV-1 gp120/NefTat vaccine adjuvanted with AS02A in antiretroviral-treated HIV-1-infected individuals. J Acquir Immune Defic Syndr. 2012 Jan 01; 59(1):1-9. PMID: 21963936; PMCID: PMC3241906.
    Citations: 8     Fields:    Translation:HumansCells
  86. Lichterfeld M, Rosenberg ES. Antiretroviral combination therapy markedly reduces risk of heterosexual HIV-1 transmission. Evid Based Med. 2012 Jun; 17(3):95-6. PMID: 22108078.
    Citations:    Fields:    
  87. Lichterfeld M, Yu XG. The emerging role of leukocyte immunoglobulin-like receptors (LILRs) in HIV-1 infection. J Leukoc Biol. 2012 Jan; 91(1):27-33. PMID: 22028331.
    Citations: 18     Fields:    Translation:HumansCells
  88. Huang J, Yang Y, Al-Mozaini M, Burke PS, Beamon J, Carrington MF, Seiss K, Rychert J, Rosenberg ES, Lichterfeld M, Yu XG. Dendritic cell dysfunction during primary HIV-1 infection. J Infect Dis. 2011 Nov 15; 204(10):1557-62. PMID: 21969335; PMCID: PMC3192192.
    Citations: 21     Fields:    Translation:HumansCells
  89. Yu XG, Lichterfeld M. Elite control of HIV: p21 (waf-1/cip-1) at its best. Cell Cycle. 2011 Oct 01; 10(19):3213-4. PMID: 21926474.
    Citations: 6     Fields:    Translation:Humans
  90. Lichterfeld M, Zachary KC. Treating HIV-1 Infection: What Might the Future Hold? Ther Adv Chronic Dis. 2011 Sep; 2(5):293-305. PMID: 23251756.
    Citations: 1     
  91. Buzon MJ, Seiss K, Weiss R, Brass AL, Rosenberg ES, Pereyra F, Yu XG, Lichterfeld M. Inhibition of HIV-1 integration in ex vivo-infected CD4 T cells from elite controllers. J Virol. 2011 Sep; 85(18):9646-50. PMID: 21734042.
    Citations: 31     Fields:    Translation:HumansCells
  92. Chen H, Li C, Huang J, Cung T, Seiss K, Beamon J, Carrington MF, Porter LC, Burke PS, Yang Y, Ryan BJ, Liu R, Weiss RH, Pereyra F, Cress WD, Brass AL, Rosenberg ES, Walker BD, Yu XG, Lichterfeld M. CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21. J Clin Invest. 2011 Apr; 121(4):1549-60. PMID: 21403397; PMCID: PMC3069774.
    Citations: 108     Fields:    Translation:HumansCells
  93. Vigneault F, Woods M, Buzon MJ, Li C, Pereyra F, Crosby SD, Rychert J, Church G, Martinez-Picado J, Rosenberg ES, Telenti A, Yu XG, Lichterfeld M. Transcriptional profiling of CD4 T cells identifies distinct subgroups of HIV-1 elite controllers. J Virol. 2011 Mar; 85(6):3015-9. PMID: 21177805.
    Citations: 42     Fields:    Translation:HumansCells
  94. Yang Y, Huang J, Toth I, Lichterfeld M, Yu XG. Mutational escape in HIV-1 CTL epitopes leads to increased binding to inhibitory myelomonocytic MHC class I receptors. PLoS One. 2010 Dec 08; 5(12):e15084. PMID: 21170342.
    Citations: 3     Fields:    Translation:HumansCells
  95. Huang J, Burke P, Yang Y, Seiss K, Beamon J, Cung T, Toth I, Pereyra F, Lichterfeld M, Yu XG. Soluble HLA-G inhibits myeloid dendritic cell function in HIV-1 infection by interacting with leukocyte immunoglobulin-like receptor B2. J Virol. 2010 Oct; 84(20):10784-91. PMID: 20702625.
    Citations: 21     Fields:    Translation:HumansCells
  96. Williams K, Seiss K, Beamon J, Pereyra F, Rosenberg ES, Walker BD, Yu XG, Lichterfeld M. Epigenetic regulation of telomerase expression in HIV-1-specific CD8+ T cells. AIDS. 2010 Jul 31; 24(12):1964-6. PMID: 20588158; PMCID: PMC2924203.
    Citations: 6     Fields:    Translation:HumansCells
  97. Huang J, Burke PS, Cung TD, Pereyra F, Toth I, Walker BD, Borges L, Lichterfeld M, Yu XG. Leukocyte immunoglobulin-like receptors maintain unique antigen-presenting properties of circulating myeloid dendritic cells in HIV-1-infected elite controllers. J Virol. 2010 Sep; 84(18):9463-71. PMID: 20631139.
    Citations: 48     Fields:    Translation:HumansCells
  98. Huang J, Goedert JJ, Sundberg EJ, Cung TD, Burke PS, Martin MP, Preiss L, Lifson J, Lichterfeld M, Carrington M, Yu XG. HLA-B*35-Px-mediated acceleration of HIV-1 infection by increased inhibitory immunoregulatory impulses. J Exp Med. 2009 Dec 21; 206(13):2959-66. PMID: 20008523.
    Citations: 41     Fields:    Translation:HumansCells
  99. Lichterfeld M, Ferraro MJ, Davis BT. High-dose daptomycin for the treatment of endocarditis caused by Staphylococcus aureus with intermediate susceptibility to glycopeptides. Int J Antimicrob Agents. 2010 Jan; 35(1):96. PMID: 19896341.
    Citations: 8     Fields:    Translation:Humans
  100. Lichterfeld M, Mou D, Cung TD, Williams KL, Waring MT, Huang J, Pereyra F, Trocha A, Freeman GJ, Rosenberg ES, Walker BD, Yu XG. Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors. Blood. 2008 Nov 01; 112(9):3679-87. PMID: 18728248; PMCID: PMC2572795.
    Citations: 34     Fields:    Translation:HumansCells
  101. Lichterfeld M, Kavanagh D, Williams KL, Mosa B, Mui S, Miura T, Allgaier R, Pereyra F, Trocha A, Feeney M, Gandhi R, Rosenberg E, Altfeld M, Allen T, Allen R, Walker B, Sundberg E, Yu XG. A Viral CTL escape mutation leading to ILT4-mediated functional inhibition of myelomonocytic cells. Journal of Experimental Medicine (in print). 2007; 204(12):2813-24.
  102. Lichterfeld M, Kavanagh DG, Williams KL, Moza B, Mui SK, Miura T, Sivamurthy R, Allgaier R, Pereyra F, Trocha A, Feeney M, Gandhi RT, Rosenberg ES, Altfeld M, Allen TM, Allen R, Walker BD, Sundberg EJ, Yu XG. A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells. J Exp Med. 2007 Nov 26; 204(12):2813-24. PMID: 18025130.
    Citations: 56     Fields:    Translation:HumansCells
  103. Yu XG, Lichterfeld M, Williams KL, Martinez-Picado J, Walker BD. Random T-cell receptor recruitment in human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells from genetically identical twins infected with the same HIV-1 strain. J Virol. 2007 Nov; 81(22):12666-9. PMID: 17804503; PMCID: PMC2169022.
    Citations: 10     Fields:    Translation:HumansCells
  104. Brainard DM, Tager AM, Misdraji J, Frahm N, Lichterfeld M, Draenert R, Brander C, Walker BD, Luster AD. Decreased CXCR3+ CD8 T cells in advanced human immunodeficiency virus infection suggest that a homing defect contributes to cytotoxic T-lymphocyte dysfunction. J Virol. 2007 Aug; 81(16):8439-50. PMID: 17553894; PMCID: PMC1951383.
    Citations: 16     Fields:    Translation:HumansCells
  105. Streeck H, Lichterfeld M, Alter G, Meier A, Teigen N, Yassine-Diab B, Sidhu HK, Little S, Kelleher A, Routy JP, Rosenberg ES, Sekaly RP, Walker BD, Altfeld M. Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles. J Virol. 2007 Jul; 81(14):7725-31. PMID: 17494064; PMCID: PMC1933382.
    Citations: 82     Fields:    Translation:HumansCells
  106. Lichterfeld M, Yu XG, Mui SK, Williams KL, Trocha A, Brockman MA, Allgaier RL, Waring MT, Koibuchi T, Johnston MN, Cohen D, Allen TM, Rosenberg ES, Walker BD, Altfeld M. Selective depletion of high-avidity human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T cells after early HIV-1 infection. J Virol. 2007 Apr; 81(8):4199-214. PMID: 17287271; PMCID: PMC1866095.
    Citations: 59     Fields:    Translation:HumansCells
  107. Yu XG, Lichterfeld M, Chetty S, Williams KL, Mui SK, Miura T, Frahm N, Feeney ME, Tang Y, Pereyra F, Labute MX, Pfafferott K, Leslie A, Crawford H, Allgaier R, Hildebrand W, Kaslow R, Brander C, Allen TM, Rosenberg ES, Kiepiela P, Vajpayee M, Goepfert PA, Altfeld M, Goulder PJ, Walker BD. Mutually exclusive T-cell receptor induction and differential susceptibility to human immunodeficiency virus type 1 mutational escape associated with a two-amino-acid difference between HLA class I subtypes. J Virol. 2007 Feb; 81(4):1619-31. PMID: 17121793; PMCID: PMC1797559.
    Citations: 50     Fields:    Translation:HumansCells
  108. Altfeld M, Kalife ET, Qi Y, Streeck H, Lichterfeld M, Johnston MN, Burgett N, Swartz ME, Yang A, Alter G, Yu XG, Meier A, Rockstroh JK, Allen TM, Jessen H, Rosenberg ES, Carrington M, Walker BD. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1. PLoS Med. 2006 Oct; 3(10):e403. PMID: 17076553; PMCID: PMC1626551.
    Citations: 183     Fields:    Translation:HumansCells
  109. Streeck H, Jessen H, Alter G, Teigen N, Waring MT, Jessen A, Stahmer I, van Lunzen J, Lichterfeld M, Gao X, Allen TM, Carrington M, Walker BD, Rockstroh JK, Altfeld M. Immunological and virological impact of highly active antiretroviral therapy initiated during acute HIV-1 infection. J Infect Dis. 2006 Sep 15; 194(6):734-9. PMID: 16941338.
    Citations: 38     Fields:    Translation:HumansCells
  110. Vogel M, Lichterfeld M, Kaufmann DE, Mui SK, Altfeld M, Voigt E, Ahlenstiel G, Kupfer B, Walker B, Spengler U, Rockstroh JK. Structured treatment interruptions following immediate initiation of HAART in eight patients with acute HIV-1 seroconversion. Eur J Med Res. 2006 Jul 31; 11(7):273-8. PMID: 16899420.
    Citations:    Fields:    Translation:HumansCells
  112. Lichterfeld M, Williams KL, Mui SK, Shah SS, Mothe BR, Sette A, Kim A, Johnston MN, Burgett N, Frahm N, Cohen D, Brander C, Rosenberg ES, Walker BD, Altfeld M, Yu XG. T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily. Int Immunol. 2006 Jul; 18(7):1179-88. PMID: 16772368.
    Citations: 8     Fields:    Translation:HumansCells
  113. Frahm N, Kiepiela P, Adams S, Linde CH, Hewitt HS, Sango K, Feeney ME, Addo MM, Lichterfeld M, Lahaie MP, Pae E, Wurcel AG, Roach T, St John MA, Altfeld M, Marincola FM, Moore C, Mallal S, Carrington M, Heckerman D, Allen TM, Mullins JI, Korber BT, Goulder PJ, Walker BD, Brander C. Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes. Nat Immunol. 2006 Feb; 7(2):173-8. PMID: 16369537.
    Citations: 122     Fields:    Translation:HumansCells
  114. Allen TM, Yu XG, Kalife ET, Reyor LL, Lichterfeld M, John M, Cheng M, Allgaier RL, Mui S, Frahm N, Alter G, Brown NV, Johnston MN, Rosenberg ES, Mallal SA, Brander C, Walker BD, Altfeld M. De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection. J Virol. 2005 Oct; 79(20):12952-60. PMID: 16188997; PMCID: PMC1235830.
    Citations: 74     Fields:    Translation:HumansCells
  115. Yu XG, Lichterfeld M, Perkins B, Kalife E, Mui S, Chen J, Cheng M, Kang W, Alter G, Brander C, Walker BD, Altfeld M. High degree of inter-clade cross-reactivity of HIV-1-specific T cell responses at the single peptide level. AIDS. 2005 Sep 23; 19(14):1449-56. PMID: 16135897.
    Citations: 15     Fields:    Translation:HumansCells
  116. Frahm N, Adams S, Kiepiela P, Linde CH, Hewitt HS, Lichterfeld M, Sango K, Brown NV, Pae E, Wurcel AG, Altfeld M, Feeney ME, Allen TM, Roach T, St John MA, Daar ES, Rosenberg E, Korber B, Marincola F, Walker BD, Goulder PJ, Brander C. HLA-B63 presents HLA-B57/B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load. J Virol. 2005 Aug; 79(16):10218-25. PMID: 16051815; PMCID: PMC1182636.
    Citations: 41     Fields:    Translation:HumansCells
  117. Lichterfeld M, Pantaleo G, Altfeld M. Loss of HIV-1-specific T cell proliferation in chronic HIV-1 infection: cause or consequence of viral replication? AIDS. 2005 Jul 22; 19(11):1225-7. PMID: 15990577.
    Citations: 3     Fields:    Translation:HumansCells
  118. Alter G, Teigen N, Davis BT, Addo MM, Suscovich TJ, Waring MT, Streeck H, Johnston MN, Staller KD, Zaman MT, Yu XG, Lichterfeld M, Basgoz N, Rosenberg ES, Altfeld M. Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection. Blood. 2005 Nov 15; 106(10):3366-9. PMID: 16002429.
    Citations: 160     Fields:    Translation:HumansCells
  119. Koibuchi T, Allen TM, Lichterfeld M, Mui SK, O'Sullivan KM, Trocha A, Kalams SA, Johnson RP, Walker BD. Limited sequence evolution within persistently targeted CD8 epitopes in chronic human immunodeficiency virus type 1 infection. J Virol. 2005 Jul; 79(13):8171-81. PMID: 15956562; PMCID: PMC1143727.
    Citations: 24     Fields:    Translation:HumansCells
  120. Lichterfeld M, Qurishi N, Hoffmann C, Hochdorfer B, Brockmeyer NH, Arasteh K, Mauss S, Rockstroh JK. Treatment of HIV-1-associated Kaposi's sarcoma with pegylated liposomal doxorubicin and HAART simultaneously induces effective tumor remission and CD4+ T cell recovery. Infection. 2005 Jun; 33(3):140-7. PMID: 15940415.
    Citations: 14     Fields:    Translation:HumansCellsCTClinical Trials
  121. Lichterfeld M, Haas S, Fischer HP, Voigt E, Rockstroh JK, Spengler U. Liver histopathology in human immunodeficiency virus-hepatitis C virus co-infected patients with fatal liver disease. J Gastroenterol Hepatol. 2005 May; 20(5):739-45. PMID: 15853988.
    Citations: 1     Fields:    Translation:Humans
  122. Altfeld M, Allen TM, Kalife ET, Frahm N, Addo MM, Mothe BR, Rathod A, Reyor LL, Harlow J, Yu XG, Perkins B, Robinson LK, Sidney J, Alter G, Lichterfeld M, Sette A, Rosenberg ES, Goulder PJ, Brander C, Walker BD. The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design. J Virol. 2005 Apr; 79(8):5000-5. PMID: 15795285; PMCID: PMC1069570.
    Citations: 21     Fields:    Translation:HumansCells
  123. Lichterfeld M, Schmeisser N, Qurishi N, Vogel M, Brackmann HH, Spengler U, Rockstroh JK. Clinical outcomes of HIV-HCV co-infection in a large cohort of hemophiliac patients. J Infect. 2005 Apr; 50(3):221-8. PMID: 15780416.
    Citations: 3     Fields:    Translation:Humans
  124. Lichterfeld M, Yu XG, Le Gall S, Altfeld M. Immunodominance of HIV-1-specific CD8(+) T-cell responses in acute HIV-1 infection: at the crossroads of viral and host genetics. Trends Immunol. 2005 Mar; 26(3):166-71. PMID: 15745859.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  125. Yu XG, Lichterfeld M, Addo MM, Altfeld M. Regulatory and accessory HIV-1 proteins: potential targets for HIV-1 vaccines? Curr Med Chem. 2005; 12(6):741-7. PMID: 15790309.
    Citations: 8     Fields:    Translation:HumansCells
  126. Kaufmann DE, Lichterfeld M, Altfeld M, Addo MM, Johnston MN, Lee PK, Wagner BS, Kalife ET, Strick D, Rosenberg ES, Walker BD. Limited durability of viral control following treated acute HIV infection. PLoS Med. 2004 Nov; 1(2):e36. PMID: 15526059; PMCID: PMC524377.
    Citations: 68     Fields:    Translation:HumansCellsCTClinical Trials
  127. Alter G, Malenfant JM, Delabre RM, Burgett NC, Yu XG, Lichterfeld M, Zaunders J, Altfeld M. Increased natural killer cell activity in viremic HIV-1 infection. J Immunol. 2004 Oct 15; 173(8):5305-11. PMID: 15470077.
    Citations: 39     Fields:    Translation:HumansCells
  128. Lichterfeld M, Kaufmann DE, Yu XG, Mui SK, Addo MM, Johnston MN, Cohen D, Robbins GK, Pae E, Alter G, Wurcel A, Stone D, Rosenberg ES, Walker BD, Altfeld M. Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells. J Exp Med. 2004 Sep 20; 200(6):701-12. PMID: 15381726; PMCID: PMC2211961.
    Citations: 159     Fields:    Translation:HumansCells
  129. Lichterfeld M, Yu XG, Cohen D, Addo MM, Malenfant J, Perkins B, Pae E, Johnston MN, Strick D, Allen TM, Rosenberg ES, Korber B, Walker BD, Altfeld M. HIV-1 Nef is preferentially recognized by CD8 T cells in primary HIV-1 infection despite a relatively high degree of genetic diversity. AIDS. 2004 Jul 02; 18(10):1383-92. PMID: 15199314.
    Citations: 56     Fields:    Translation:HumansCells
  130. Nischalke HD, Nattermann J, Lichterfeld M, Woitas RP, Rockstroh JK, Sauerbruch T, Spengler U. Rapid determination of the Delta32 deletion in the human CC-chemokine receptor 5 (CCR5) gene without DNA extraction by lightcycler real-time polymerase chain reaction. AIDS Res Hum Retroviruses. 2004 Jul; 20(7):750-4. PMID: 15307921.
    Citations: 3     Fields:    Translation:Humans
  131. Allen TM, Altfeld M, Yu XG, O'Sullivan KM, Lichterfeld M, Le Gall S, John M, Mothe BR, Lee PK, Kalife ET, Cohen DE, Freedberg KA, Strick DA, Johnston MN, Sette A, Rosenberg ES, Mallal SA, Goulder PJ, Brander C, Walker BD. Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection. J Virol. 2004 Jul; 78(13):7069-78. PMID: 15194783; PMCID: PMC421658.
    Citations: 152     Fields:    Translation:HumansCells
  132. Kaufmann DE, Bailey PM, Sidney J, Wagner B, Norris PJ, Johnston MN, Cosimi LA, Addo MM, Lichterfeld M, Altfeld M, Frahm N, Brander C, Sette A, Walker BD, Rosenberg ES. Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides. J Virol. 2004 May; 78(9):4463-77. PMID: 15078927; PMCID: PMC387674.
    Citations: 90     Fields:    Translation:HumansCells
  133. Yu XG, Addo MM, Perkins BA, Wej F, Rathod A, Geer SC, Parta M, Cohen D, Stone DR, Russell CJ, Tanzi G, Mei S, Wurcel AG, Frahm N, Lichterfeld M, Heath L, Mullins JI, Marincola F, Goulder PJ, Brander C, Allen T, Cao Y, Walker BD, Altfeld M. Differences in the expressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians. AIDS Res Hum Retroviruses. 2004 May; 20(5):557-64. PMID: 15186531.
    Citations: 7     Fields:    Translation:HumansCells
  134. Lichterfeld M, Yu XG, Waring MT, Mui SK, Johnston MN, Cohen D, Addo MM, Zaunders J, Alter G, Pae E, Strick D, Allen TM, Rosenberg ES, Walker BD, Altfeld M. HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8(+) T cells producing both interferon-gamma and tumor necrosis factor-alpha. Blood. 2004 Jul 15; 104(2):487-94. PMID: 15059848.
    Citations: 61     Fields:    Translation:HumansCells
  135. Tarrand JJ, Lichterfeld M, Warraich I, Luna M, Han XY, May GS, Kontoyiannis DP. Diagnosis of invasive septate mold infections. A correlation of microbiological culture and histologic or cytologic examination. Am J Clin Pathol. 2003 Jun; 119(6):854-8. PMID: 12817433.
    Citations: 68     Fields:    Translation:HumansAnimals
  136. Lichterfeld M, Rockstroh JK. [Antiretroviral treatment of HIV infected patients]. Med Monatsschr Pharm. 2003 Apr; 26(4):111-21; quiz 121-2. PMID: 12722525.
    Citations:    Fields:    Translation:Humans
  137. Lichterfeld M, Nischalke HD, van Lunzen J, Söhne J, Schmeisser N, Woitas R, Sauerbruch T, Rockstroh JK, Spengler U. The tandem-repeat polymorphism of the DC-SIGNR gene does not affect the susceptibility to HIV infection and the progression to AIDS. Clin Immunol. 2003 Apr; 107(1):55-9. PMID: 12738250.
    Citations: 14     Fields:    Translation:HumansCells
  138. Lichterfeld M, Wöhrmann A, Schmeisser N, Fätkenheuer G, Salzberger B, Wyen C, Schmitz K, Sauerbruch T, Rockstroh JK. Superior virological efficacy of ritonavir-boosted protease inhibitor regimens compared to single protease inhibitor therapy. Eur J Med Res. 2003 Feb 21; 8(2):56-60. PMID: 12626282.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  139. Lichterfeld M, Fischer HP, Spengler U, Rockstroh JK. [Fatty liver and increased serum lactate in a woman with HIV]. Dtsch Med Wochenschr. 2003 Jan 17; 128(3):81-4. PMID: 12529837.
    Citations: 3     Fields:    Translation:HumansCells
  140. Rockstroh JK, Mudar M, Lichterfeld M, Nischalke HD, Klausen G, Gölz J, Dupke S, Notheis G, Stein L, Mauss S. Pilot study of interferon alpha high-dose induction therapy in combination with ribavirin for chronic hepatitis C in HIV-co-infected patients. AIDS. 2002 Oct 18; 16(15):2083-5. PMID: 12370510.
    Citations: 3     Fields:    Translation:Humans
  141. Lichterfeld M, Leifeld L, Nischalke HD, Rockstroh JK, Hess L, Sauerbruch T, Spengler U. Reduced CC chemokine receptor (CCR) 1 and CCR5 surface expression on peripheral blood T lymphocytes from patients with chronic hepatitis C infection. J Infect Dis. 2002 Jun 15; 185(12):1803-7. PMID: 12085329.
    Citations: 17     Fields:    Translation:HumansCells
  142. Spengler U, Lichterfeld M, Rockstroh JK. Antiretroviral drug toxicity -- a challenge for the hepatologist? J Hepatol. 2002 Feb; 36(2):283-94. PMID: 11830343.
    Citations: 9     Fields:    Translation:Humans
  143. Lichterfeld M, Nischalke HD, Bergmann F, Wiesel W, Rieke A, Theisen A, Fätkenheuer G, Oette M, Carls H, Fenske S, Nadler M, Knechten H, Wasmuth JC, Rockstroh JK. Long-term efficacy and safety of ritonavir/indinavir at 400/400 mg twice a day in combination with two nucleoside reverse transcriptase inhibitors as first line antiretroviral therapy. HIV Med. 2002 Jan; 3(1):37-43. PMID: 12059949.
    Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
  144. Lichterfeld M, Lorenz C, Nischalke HD, Scheurlen C, Sauerbruch T, Rockstroh JK. Decreased prevalence of Helicobacter pylori infection in HIV patients with AIDS defining diseases. Z Gastroenterol. 2002 Jan; 40(1):11-4. PMID: 11803495.
    Citations: 7     Fields:    Translation:HumansCells
  145. Lichterfeld M, Martin S, Burkly L, Haas R, Kronenwett R. Mobilization of CD34+ haematopoietic stem cells is associated with a functional inactivation of the integrin very late antigen 4. Br J Haematol. 2000 Jul; 110(1):71-81. PMID: 10930981.
    Citations: 14     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.