Harvard Catalyst Profiles

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Caroline Danielle Aline Rouaux, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Scekic-Zahirovic J, Fischer M, Stuart-Lopez G, Burg T, Gilet J, Dirrig-Grosch S, Marques C, Birling MC, Kessler P, Rouaux C. Evidence that corticofugal propagation of ALS pathology is not mediated by prion-like mechanism. Prog Neurobiol. 2020 Dec 09; 101972. PMID: 33309802.
    Citations: 1     Fields:    
  2. Burg T, Bichara C, Scekic-Zahirovic J, Fischer M, Stuart-Lopez G, Brunet A, Lefebvre F, Cordero-Erausquin M, Rouaux C. Absence of Subcerebral Projection Neurons Is Beneficial in a Mouse Model of Amyotrophic Lateral Sclerosis. Ann Neurol. 2020 10; 88(4):688-702. PMID: 32588450.
    Citations: 1     Fields:    Translation:AnimalsCells
  3. Brunet A, Stuart-Lopez G, Burg T, Scekic-Zahirovic J, Rouaux C. Cortical Circuit Dysfunction as a Potential Driver of Amyotrophic Lateral Sclerosis. Front Neurosci. 2020; 14:363. PMID: 32410944.
    Citations: 4     
  4. Rouaux C, Gonzalez De Aguilar JL, Dupuis L. Unmasking the skiptic task of TDP-43. EMBO J. 2018 06 01; 37(11). PMID: 29769403.
    Citations: 2     Fields:    Translation:AnimalsCells
  5. Tibshirani M, Zhao B, Gentil BJ, Minotti S, Marques C, Keith J, Rogaeva E, Zinman L, Rouaux C, Robertson J, Durham HD. Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis. Hum Mol Genet. 2017 11 01; 26(21):4142-4152. PMID: 28973294.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  6. El Oussini H, Scekic-Zahirovic J, Vercruysse P, Marques C, Dirrig-Grosch S, Dieterlé S, Picchiarelli G, Sinniger J, Rouaux C, Dupuis L. Degeneration of serotonin neurons triggers spasticity in amyotrophic lateral sclerosis. Ann Neurol. 2017 Sep; 82(3):444-456. PMID: 28856708.
    Citations: 6     Fields:    Translation:AnimalsCells
  7. Scekic-Zahirovic J, Sendscheid O, El Oussini H, Jambeau M, Sun Y, Mersmann S, Wagner M, Dieterlé S, Sinniger J, Dirrig-Grosch S, Drenner K, Birling MC, Qiu J, Zhou Y, Li H, Fu XD, Rouaux C, Shelkovnikova T, Witting A, Ludolph AC, Kiefer F, Storkebaum E, Lagier-Tourenne C, Dupuis L. Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss. EMBO J. 2016 05 17; 35(10):1077-97. PMID: 26951610.
    Citations: 66     Fields:    Translation:AnimalsCells
  8. Ye Z, Mostajo-Radji MA, Brown JR, Rouaux C, Tomassy GS, Hensch TK, Arlotta P. Instructing Perisomatic Inhibition by Direct Lineage Reprogramming of Neocortical Projection Neurons. Neuron. 2015 Nov 04; 88(3):475-83. PMID: 26539889.
    Citations: 20     Fields:    Translation:AnimalsCells
  9. Rouaux C, Hedin-Pereira C, Costa MR. Editorial: Progenitor diversity and neural cell specification in the central nervous system. Front Cell Neurosci. 2015; 9:358. PMID: 26441529.
  10. Heinrich C, Rouaux C. [Inducing brain regeneration from within: in vivo reprogramming of endogenous somatic cells into neurons]. Med Sci (Paris). 2015 Jan; 31(1):35-42. PMID: 25658729.
    Citations: 1     Fields:    Translation:HumansCells
  11. Rouaux C, Arlotta P. Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo. Nat Cell Biol. 2013 Feb; 15(2):214-21. PMID: 23334497.
    Citations: 86     Fields:    Translation:AnimalsCells
  12. Rouaux C, Bhai S, Arlotta P. Programming and reprogramming neuronal subtypes in the central nervous system. Dev Neurobiol. 2012 Jul; 72(7):1085-98. PMID: 22378700.
    Citations: 6     Fields:    Translation:AnimalsCells
  13. Lodato S, Rouaux C, Quast KB, Jantrachotechatchawan C, Studer M, Hensch TK, Arlotta P. Excitatory projection neuron subtypes control the distribution of local inhibitory interneurons in the cerebral cortex. Neuron. 2011 Feb 24; 69(4):763-79. PMID: 21338885.
    Citations: 76     Fields:    Translation:AnimalsCells
  14. Rouaux C, Arlotta P. Fezf2 directs the differentiation of corticofugal neurons from striatal progenitors in vivo. Nat Neurosci. 2010 Nov; 13(11):1345-7. PMID: 20953195.
    Citations: 58     Fields:    Translation:AnimalsCells
  15. Dupuis L, Pehar M, Cassina P, Rene F, Castellanos R, Rouaux C, Gandelman M, Dimou L, Schwab ME, Loeffler JP, Barbeito L, Gonzalez de Aguilar JL. Nogo receptor antagonizes p75NTR-dependent motor neuron death. Proc Natl Acad Sci U S A. 2008 Jan 15; 105(2):740-5. PMID: 18182498.
    Citations: 12     Fields:    Translation:AnimalsCells
  16. Boutillier S, Lannes B, Buée L, Delacourte A, Rouaux C, Mohr M, Bellocq JP, Sellal F, Larmet Y, Boutillier AL, Loeffler JP. Sp3 and sp4 transcription factor levels are increased in brains of patients with Alzheimer's disease. Neurodegener Dis. 2007; 4(6):413-23. PMID: 17934324.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  17. Panteleeva I, Boutillier S, See V, Spiller DG, Rouaux C, Almouzni G, Bailly D, Maison C, Lai HC, Loeffler JP, Boutillier AL. HP1alpha guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation. EMBO J. 2007 Aug 08; 26(15):3616-28. PMID: 17627279.
    Citations: 30     Fields:    Translation:AnimalsCells
  18. Rouaux C, Panteleeva I, René F, Gonzalez de Aguilar JL, Echaniz-Laguna A, Dupuis L, Menger Y, Boutillier AL, Loeffler JP. Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse model. J Neurosci. 2007 May 23; 27(21):5535-45. PMID: 17522299.
    Citations: 77     Fields:    Translation:AnimalsCells
  19. Höglinger GU, Breunig JJ, Depboylu C, Rouaux C, Michel PP, Alvarez-Fischer D, Boutillier AL, Degregori J, Oertel WH, Rakic P, Hirsch EC, Hunot S. The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease. Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9):3585-90. PMID: 17360686.
    Citations: 102     Fields:    Translation:HumansAnimalsCells
  20. Panteleeva I, Rouaux C, Larmet Y, Boutillier S, Loeffler JP, Boutillier AL. HDAC-3 participates in the repression of e2f-dependent gene transcription in primary differentiated neurons. Ann N Y Acad Sci. 2004 Dec; 1030:656-60. PMID: 15659849.
    Citations: 9     Fields:    Translation:HumansCells
  21. Rouaux C, Loeffler JP, Boutillier AL. Targeting CREB-binding protein (CBP) loss of function as a therapeutic strategy in neurological disorders. Biochem Pharmacol. 2004 Sep 15; 68(6):1157-64. PMID: 15313413.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  22. Rouaux C, Jokic N, Mbebi C, Boutillier S, Loeffler JP, Boutillier AL. Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration. EMBO J. 2003 Dec 15; 22(24):6537-49. PMID: 14657026.
    Citations: 105     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.