Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Martin Joseph Kelly Jr., M.D.

Title
Institution
Department
Address
Phone

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Stincic TL, Rønnekleiv OK, Kelly MJ. Membrane and nuclear initiated estrogenic regulation of homeostasis. Steroids. 2019 Jun 20; 108428. PMID: 31229508.
    Citations:    
  2. Qiu J, Bosch MA, Zhang C, Rønnekleiv OK, Kelly MJ. Estradiol Protects Neuropeptide Y/Agouti-related Peptide Neurons against Insulin Resistance in Females. Neuroendocrinology. 2019 Jun 19. PMID: 31212279.
    Citations:    
  3. Stincic TL, Grachev P, Bosch MA, Rønnekleiv OK, Kelly MJ. Estradiol Drives the Anorexigenic Activity of Proopiomelanocortin Neurons in Female Mice. eNeuro. 2018 Jul-Aug; 5(4). PMID: 30310864.
    Citations:    Fields:    
  4. Qiu J, Rivera HM, Bosch MA, Padilla SL, Stincic TL, Palmiter RD, Kelly MJ, Rønnekleiv OK. Estrogenic-dependent glutamatergic neurotransmission from kisspeptin neurons governs feeding circuits in females. Elife. 2018 08 06; 7. PMID: 30079889.
    Citations:    Fields:    
  5. Kelly MJ, Qiu J, Rønnekleiv OK. TRPCing around the hypothalamus. Front Neuroendocrinol. 2018 10; 51:116-124. PMID: 29859883.
    Citations:    Fields:    
  6. Stincic TL, Rønnekleiv OK, Kelly MJ. Diverse actions of estradiol on anorexigenic and orexigenic hypothalamic arcuate neurons. Horm Behav. 2018 08; 104:146-155. PMID: 29626486.
    Citations: 1     Fields:    
  7. Lehman MN, Coolen LM, Steiner RA, Neal-Perry G, Wang L, Moenter SM, Moore AM, Goodman RL, Hwa-Yeo S, Padilla SL, Kauffman AS, Garcia J, Kelly MJ, Clarkson J, Radovick S, Babwah AV, Leon S, Tena-Sempere M, Comninos A, Seminara S, Dhillo WS, Levine J, Terasawa E, Negron A, Herbison AE. The 3rd World Conference on Kisspeptin, "Kisspeptin 2017: Brain and Beyond":Unresolved questions, challenges and future directions for the field. J Neuroendocrinol. 2018 Apr 14; e12600. PMID: 29656508.
    Citations:    Fields:    
  8. Qiu J, Bosch MA, Meza C, Navarro UV, Nestor CC, Wagner EJ, Rønnekleiv OK, Kelly MJ. Estradiol Protects Proopiomelanocortin Neurons Against Insulin Resistance. Endocrinology. 2018 02 01; 159(2):647-664. PMID: 29165691.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  9. Qiu J, Wagner EJ, Rønnekleiv OK, Kelly MJ. Insulin and leptin excite anorexigenic pro-opiomelanocortin neurones via activation of TRPC5 channels. J Neuroendocrinol. 2018 02; 30(2). PMID: 28675783.
    Citations: 3     Fields:    
  10. Chan W, Drummond A, Kelly M. Deep vein thrombosis in a transgender woman. CMAJ. 2017 04 03; 189(13):E502-E504. PMID: 28385895.
    Citations: 2     Fields:    Translation:Humans
  11. Padilla SL, Qiu J, Nestor CC, Zhang C, Smith AW, Whiddon BB, Rønnekleiv OK, Kelly MJ, Palmiter RD. AgRP to Kiss1 neuron signaling links nutritional state and fertility. Proc Natl Acad Sci U S A. 2017 02 28; 114(9):2413-2418. PMID: 28196880.
    Citations: 10     Fields:    Translation:AnimalsCells
  12. Qiu J, Nestor CC, Zhang C, Padilla SL, Palmiter RD, Kelly MJ, Rønnekleiv OK. High-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neurons. Elife. 2016 08 23; 5. PMID: 27549338.
    Citations: 17     Fields:    Translation:AnimalsCells
  13. Nestor CC, Qiu J, Padilla SL, Zhang C, Bosch MA, Fan W, Aicher SA, Palmiter RD, Rønnekleiv OK, Kelly MJ. Optogenetic Stimulation of Arcuate Nucleus Kiss1 Neurons Reveals a Steroid-Dependent Glutamatergic Input to POMC and AgRP Neurons in Male Mice. Mol Endocrinol. 2016 Jun; 30(6):630-44. PMID: 27093227.
    Citations: 10     Fields:    Translation:AnimalsCells
  14. Padilla SL, Qiu J, Soden ME, Sanz E, Nestor CC, Barker FD, Quintana A, Zweifel LS, Rønnekleiv OK, Kelly MJ, Palmiter RD. Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state. Nat Neurosci. 2016 05; 19(5):734-741. PMID: 27019015.
    Citations: 24     Fields:    Translation:AnimalsCells
  15. Kelly MJ, Feeley IH, O'Byrne JM. A Qualitative and Quantitative Comparative Analysis of Commercial and Independent Online Information for Hip Surgery: A Bias in Online Information Targeting Patients? J Arthroplasty. 2016 10; 31(10):2124-9. PMID: 27071521.
    Citations:    Fields:    Translation:Humans
  16. Conde K, Meza C, Kelly MJ, Sinchak K, Wagner EJ. Estradiol Rapidly Attenuates ORL-1 Receptor-Mediated Inhibition of Proopiomelanocortin Neurons via Gq-Coupled, Membrane-Initiated Signaling. Neuroendocrinology. 2016; 103(6):787-805. PMID: 26765570.
    Citations: 6     Fields:    Translation:AnimalsCells
  17. Kelly MJ, O'Keeffe GW, Sullivan AM. Viral vector delivery of neurotrophic factors for Parkinson's disease therapy. Expert Rev Mol Med. 2015 May 13; 17:e8. PMID: 25997719.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  18. Kelly MJ, Rønnekleiv OK. Minireview: neural signaling of estradiol in the hypothalamus. Mol Endocrinol. 2015 May; 29(5):645-57. PMID: 25751314.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  19. Zhang C, Bosch MA, Qiu J, Rønnekleiv OK, Kelly MJ. 17ß-Estradiol increases persistent Na(+) current and excitability of AVPV/PeN Kiss1 neurons in female mice. Mol Endocrinol. 2015 Apr; 29(4):518-27. PMID: 25734516.
    Citations: 10     Fields:    Translation:AnimalsCells
  20. Rønnekleiv OK, Zhang C, Bosch MA, Kelly MJ. Kisspeptin and Gonadotropin-Releasing Hormone Neuronal Excitability: Molecular Mechanisms Driven by 17ß-Estradiol. Neuroendocrinology. 2015; 102(3):184-93. PMID: 25612870.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  21. Rønnekleiv OK, Fang Y, Zhang C, Nestor CC, Mao P, Kelly MJ. Research resource: Gene profiling of G protein-coupled receptors in the arcuate nucleus of the female. Mol Endocrinol. 2014 Aug; 28(8):1362-80. PMID: 24933249.
    Citations: 7     Fields:    Translation:AnimalsCells
  22. Qiu J, Zhang C, Borgquist A, Nestor CC, Smith AW, Bosch MA, Ku S, Wagner EJ, Rønnekleiv OK, Kelly MJ. Insulin excites anorexigenic proopiomelanocortin neurons via activation of canonical transient receptor potential channels. Cell Metab. 2014 Apr 01; 19(4):682-93. PMID: 24703699.
    Citations: 38     Fields:    Translation:AnimalsCells
  23. Nestor CC, Kelly MJ, Rønnekleiv OK. Cross-talk between reproduction and energy homeostasis: central impact of estrogens, leptin and kisspeptin signaling. Horm Mol Biol Clin Investig. 2014 Mar; 17(3):109-28. PMID: 25372735.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  24. Zhang C, Tonsfeldt KJ, Qiu J, Bosch MA, Kobayashi K, Steiner RA, Kelly MJ, Rønnekleiv OK. Molecular mechanisms that drive estradiol-dependent burst firing of Kiss1 neurons in the rostral periventricular preoptic area. Am J Physiol Endocrinol Metab. 2013 Dec 01; 305(11):E1384-97. PMID: 24105416.
    Citations: 19     Fields:    Translation:AnimalsCells
  25. Kelly MJ, Zhang C, Qiu J, Rønnekleiv OK. Pacemaking kisspeptin neurons. Exp Physiol. 2013 Nov; 98(11):1535-43. PMID: 23884368.
    Citations: 10     Fields:    Translation:AnimalsCells
  26. Smith AW, Bosch MA, Wagner EJ, Rønnekleiv OK, Kelly MJ. The membrane estrogen receptor ligand STX rapidly enhances GABAergic signaling in NPY/AgRP neurons: role in mediating the anorexigenic effects of 17ß-estradiol. Am J Physiol Endocrinol Metab. 2013 Sep 01; 305(5):E632-40. PMID: 23820624.
    Citations: 27     Fields:    Translation:AnimalsCells
  27. Zhang C, Bosch MA, Rønnekleiv OK, Kelly MJ. Kisspeptin activation of TRPC4 channels in female GnRH neurons requires PIP2 depletion and cSrc kinase activation. Endocrinology. 2013 Aug; 154(8):2772-83. PMID: 23744639.
    Citations: 13     Fields:    Translation:AnimalsCells
  28. Kaufman KR, Kelly MJ, Roselli CE. Rapid effects of 17ß-estradiol on male copulatory behaviors are not elicited by the novel membrane active estrogenic compound STX. Behav Neurosci. 2013 Aug; 127(4):598-605. PMID: 23731070.
    Citations: 1     Fields:    Translation:Animals
  29. Zhang C, Rønnekleiv OK, Kelly MJ. Kisspeptin inhibits a slow afterhyperpolarization current via protein kinase C and reduces spike frequency adaptation in GnRH neurons. Am J Physiol Endocrinol Metab. 2013 Jun 01; 304(11):E1237-44. PMID: 23548613.
    Citations: 6     Fields:    Translation:AnimalsCells
  30. Kelly MJ, Rønnekleiv OK. A selective membrane estrogen receptor agonist maintains autonomic functions in hypoestrogenic states. Brain Res. 2013 Jun 13; 1514:75-82. PMID: 23535448.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  31. Rønnekleiv OK, Kelly MJ. Kisspeptin excitation of GnRH neurons. Adv Exp Med Biol. 2013; 784:113-31. PMID: 23550004.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  32. Micevych PE, Kelly MJ. Membrane estrogen receptor regulation of hypothalamic function. Neuroendocrinology. 2012; 96(2):103-10. PMID: 22538318.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  33. Kelly MJ. Introduction. Neuroendocrinology. 2012; 96(2):101-2. PMID: 22986409.
    Citations:    Fields:    Translation:HumansAnimalsCells
  34. Washburn N, Borgquist A, Wang K, Jeffery GS, Kelly MJ, Wagner EJ. Receptor subtypes and signal transduction mechanisms contributing to the estrogenic attenuation of cannabinoid-induced changes in energy homeostasis. Neuroendocrinology. 2013; 97(2):160-75. PMID: 22538462.
    Citations: 12     Fields:    Translation:AnimalsCells
  35. Kelly MJ, Rønnekleiv OK. Membrane-initiated actions of estradiol that regulate reproduction, energy balance and body temperature. Front Neuroendocrinol. 2012 Oct; 33(4):376-87. PMID: 22871514.
    Citations: 15     Fields:    Translation:Humans
  36. Azzopardi P, Brown AD, Zimmet P, Fahy RE, Dent GA, Kelly MJ, Kranzusch K, Maple-Brown LJ, Nossar V, Silink M, Sinha AK, Stone ML, Wren SJ. Type 2 diabetes in young Indigenous Australians in rural and remote areas: diagnosis, screening, management and prevention. Med J Aust. 2012 Jul 02; 197(1):32-6. PMID: 22762229.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  37. Ropero AB, Alonso-Magdalena P, Soriano S, Juan-Picó P, Roepke TA, Kelly MJ, Nadal Á. Insulinotropic effect of the non-steroidal compound STX in pancreatic ß-cells. PLoS One. 2012; 7(4):e34650. PMID: 22506040.
    Citations:    Fields:    Translation:AnimalsCells
  38. Roepke TA, Smith AW, Rønnekleiv OK, Kelly MJ. Serotonin 5-HT2C receptor-mediated inhibition of the M-current in hypothalamic POMC neurons. Am J Physiol Endocrinol Metab. 2012 Jun 01; 302(11):E1399-406. PMID: 22436698.
    Citations: 14     Fields:    Translation:AnimalsCells
  39. Gottsch ML, Popa SM, Lawhorn JK, Qiu J, Tonsfeldt KJ, Bosch MA, Kelly MJ, Rønnekleiv OK, Sanz E, McKnight GS, Clifton DK, Palmiter RD, Steiner RA. Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse. Endocrinology. 2011 Nov; 152(11):4298-309. PMID: 21933870.
    Citations: 50     Fields:    Translation:AnimalsCells
  40. Roepke TA, Qiu J, Smith AW, Rønnekleiv OK, Kelly MJ. Fasting and 17ß-estradiol differentially modulate the M-current in neuropeptide Y neurons. J Neurosci. 2011 Aug 17; 31(33):11825-35. PMID: 21849543.
    Citations: 28     Fields:    Translation:AnimalsCells
  41. Hammes SR, Kelly MJ, Slingerland JM. The physiology of integrated nuclear and extranuclear steroid signaling: introductory comments. Steroids. 2011 Aug; 76(9):821. PMID: 21645536.
    Citations:    Fields:    Translation:HumansAnimalsCells
  42. Qiu J, Fang Y, Bosch MA, Rønnekleiv OK, Kelly MJ. Guinea pig kisspeptin neurons are depolarized by leptin via activation of TRPC channels. Endocrinology. 2011 Apr; 152(4):1503-14. PMID: 21285322.
    Citations: 32     Fields:    Translation:AnimalsCells
  43. Roepke TA, Ronnekleiv OK, Kelly MJ. Physiological consequences of membrane-initiated estrogen signaling in the brain. Front Biosci (Landmark Ed). 2011 Jan 01; 16:1560-73. PMID: 21196248.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  44. Kelly MJ, Qiu J. Estrogen signaling in hypothalamic circuits controlling reproduction. Brain Res. 2010 Dec 10; 1364:44-52. PMID: 20807512.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  45. Roepke TA, Bosch MA, Rick EA, Lee B, Wagner EJ, Seidlova-Wuttke D, Wuttke W, Scanlan TS, Rønnekleiv OK, Kelly MJ. Contribution of a membrane estrogen receptor to the estrogenic regulation of body temperature and energy homeostasis. Endocrinology. 2010 Oct; 151(10):4926-37. PMID: 20685867.
    Citations: 41     Fields:    Translation:AnimalsCells
  46. Zhang C, Kelly MJ, Rønnekleiv OK. 17 ß-estradiol rapidly increases ATP-sensitive potassium channel activity in gonadotropin-releasing hormone neurons [corrected] via a protein kinase signaling pathway. Endocrinology. 2010 Sep; 151(9):4477-84. PMID: 20660067.
    Citations: 39     Fields:    Translation:AnimalsCells
  47. Qiu J, Fang Y, Rønnekleiv OK, Kelly MJ. Leptin excites proopiomelanocortin neurons via activation of TRPC channels. J Neurosci. 2010 Jan 27; 30(4):1560-5. PMID: 20107083.
    Citations: 83     Fields:    Translation:AnimalsCells
  48. Lebesgue D, Traub M, De Butte-Smith M, Chen C, Zukin RS, Kelly MJ, Etgen AM. Acute administration of non-classical estrogen receptor agonists attenuates ischemia-induced hippocampal neuron loss in middle-aged female rats. PLoS One. 2010 Jan 08; 5(1):e8642. PMID: 20062809.
    Citations: 49     Fields:    Translation:AnimalsCells
  49. Zhang C, Bosch MA, Rick EA, Kelly MJ, Rønnekleiv OK. 17Beta-estradiol regulation of T-type calcium channels in gonadotropin-releasing hormone neurons. J Neurosci. 2009 Aug 26; 29(34):10552-62. PMID: 19710308.
    Citations: 49     Fields:    Translation:AnimalsCells
  50. Kelly MJ, Rønnekleiv OK. Control of CNS neuronal excitability by estrogens via membrane-initiated signaling. Mol Cell Endocrinol. 2009 Sep 24; 308(1-2):17-25. PMID: 19549588.
    Citations: 33     Fields:    Translation:Cells
  51. Roepke TA, Qiu J, Bosch MA, Rønnekleiv OK, Kelly MJ. Cross-talk between membrane-initiated and nuclear-initiated oestrogen signalling in the hypothalamus. J Neuroendocrinol. 2009 Mar; 21(4):263-70. PMID: 19187465.
    Citations: 28     Fields:    Translation:AnimalsCells
  52. Zhang C, Bosch MA, Rønnekleiv OK, Kelly MJ. Gamma-aminobutyric acid B receptor mediated inhibition of gonadotropin-releasing hormone neurons is suppressed by kisspeptin-G protein-coupled receptor 54 signaling. Endocrinology. 2009 May; 150(5):2388-94. PMID: 19164470.
    Citations: 33     Fields:    Translation:AnimalsCells
  53. Bosch MA, Hou J, Fang Y, Kelly MJ, Rønnekleiv OK. 17Beta-estradiol regulation of the mRNA expression of T-type calcium channel subunits: role of estrogen receptor alpha and estrogen receptor beta. J Comp Neurol. 2009 Jan 20; 512(3):347-58. PMID: 19003958.
    Citations: 19     Fields:    Translation:Animals
  54. Qiu J, Bosch MA, Rønnekleiv OK, Kloosterboer HJ, Kelly MJ. Tibolone rapidly attenuates the GABAB response in hypothalamic neurones. J Neuroendocrinol. 2008 Dec; 20(12):1310-8. PMID: 19094079.
    Citations: 3     Fields:    Translation:AnimalsCells
  55. Srivastava J, Barreiro G, Groscurth S, Gingras AR, Goult BT, Critchley DR, Kelly MJ, Jacobson MP, Barber DL. Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14436-41. PMID: 18780792.
    Citations: 35     Fields:    Translation:AnimalsCells
  56. Roepke TA, Xue C, Bosch MA, Scanlan TS, Kelly MJ, Rønnekleiv OK. Genes associated with membrane-initiated signaling of estrogen and energy homeostasis. Endocrinology. 2008 Dec; 149(12):6113-24. PMID: 18755790.
    Citations: 42     Fields:    Translation:AnimalsCells
  57. Kelly MJ, Rønnekleiv OK. Membrane-initiated estrogen signaling in hypothalamic neurons. Mol Cell Endocrinol. 2008 Aug 13; 290(1-2):14-23. PMID: 18538919.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  58. Zhang C, Roepke TA, Kelly MJ, Rønnekleiv OK. Kisspeptin depolarizes gonadotropin-releasing hormone neurons through activation of TRPC-like cationic channels. J Neurosci. 2008 Apr 23; 28(17):4423-34. PMID: 18434521.
    Citations: 79     Fields:    Translation:AnimalsCells
  59. Malyala A, Zhang C, Bryant DN, Kelly MJ, Rønnekleiv OK. PI3K signaling effects in hypothalamic neurons mediated by estrogen. J Comp Neurol. 2008 Feb 20; 506(6):895-911. PMID: 18085586.
    Citations: 45     Fields:    Translation:AnimalsCells
  60. Qiu J, Rønnekleiv OK, Kelly MJ. Modulation of hypothalamic neuronal activity through a novel G-protein-coupled estrogen membrane receptor. Steroids. 2008 Oct; 73(9-10):985-91. PMID: 18342349.
    Citations: 58     Fields:    Translation:AnimalsCells
  61. Xu C, Roepke TA, Zhang C, Rønnekleiv OK, Kelly MJ. Gonadotropin-releasing hormone (GnRH) activates the m-current in GnRH neurons: an autoregulatory negative feedback mechanism? Endocrinology. 2008 May; 149(5):2459-66. PMID: 18218690.
    Citations: 18     Fields:    Translation:AnimalsCells
  62. Wang C, Dehghani B, Magrisso IJ, Rick EA, Bonhomme E, Cody DB, Elenich LA, Subramanian S, Murphy SJ, Kelly MJ, Rosenbaum JS, Vandenbark AA, Offner H. GPR30 contributes to estrogen-induced thymic atrophy. Mol Endocrinol. 2008 Mar; 22(3):636-48. PMID: 18063692.
    Citations: 63     Fields:    Translation:AnimalsCells
  63. Zhang C, Bosch MA, Levine JE, Rønnekleiv OK, Kelly MJ. Gonadotropin-releasing hormone neurons express K(ATP) channels that are regulated by estrogen and responsive to glucose and metabolic inhibition. J Neurosci. 2007 Sep 19; 27(38):10153-64. PMID: 17881521.
    Citations: 59     Fields:    Translation:AnimalsCells
  64. Qiu J, Xue C, Bosch MA, Murphy JG, Fan W, Rønnekleiv OK, Kelly MJ. Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons: role in energy homeostasis in females. Mol Pharmacol. 2007 Oct; 72(4):885-96. PMID: 17622577.
    Citations: 42     Fields:    Translation:AnimalsCells
  65. Roepke TA, Malyala A, Bosch MA, Kelly MJ, Rønnekleiv OK. Estrogen regulation of genes important for K+ channel signaling in the arcuate nucleus. Endocrinology. 2007 Oct; 148(10):4937-51. PMID: 17595223.
    Citations: 39     Fields:    Translation:AnimalsCells
  66. Rønnekleiv OK, Malyala A, Kelly MJ. Membrane-initiated signaling of estrogen in the brain. Semin Reprod Med. 2007 May; 25(3):165-77. PMID: 17447206.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  67. Qiu J, Bosch MA, Jamali K, Xue C, Kelly MJ, Rønnekleiv OK. Estrogen upregulates T-type calcium channels in the hypothalamus and pituitary. J Neurosci. 2006 Oct 25; 26(43):11072-82. PMID: 17065449.
    Citations: 22     Fields:    Translation:AnimalsCells
  68. Qiu J, Bosch MA, Tobias SC, Krust A, Graham SM, Murphy SJ, Korach KS, Chambon P, Scanlan TS, Rønnekleiv OK, Kelly MJ. A G-protein-coupled estrogen receptor is involved in hypothalamic control of energy homeostasis. J Neurosci. 2006 May 24; 26(21):5649-55. PMID: 16723521.
    Citations: 96     Fields:    Translation:AnimalsCells
  69. Tobias SC, Qiu J, Kelly MJ, Scanlan TS. Synthesis and biological evaluation of SERMs with potent nongenomic estrogenic activity. ChemMedChem. 2006 May; 1(5):565-71. PMID: 16892393.
    Citations: 21     Fields:    
  70. Rønnekleiv OK, Kelly MJ. Diversity of ovarian steroid signaling in the hypothalamus. Front Neuroendocrinol. 2005 Sep; 26(2):65-84. PMID: 16009409.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  71. Malyala A, Kelly MJ, Rønnekleiv OK. Estrogen modulation of hypothalamic neurons: activation of multiple signaling pathways and gene expression changes. Steroids. 2005 May-Jun; 70(5-7):397-406. PMID: 15862823.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  72. Kelly MJ, Qiu J, Rønnekleiv OK. Estrogen signaling in the hypothalamus. Vitam Horm. 2005; 71:123-45. PMID: 16112267.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  73. Malyala A, Pattee P, Nagalla SR, Kelly MJ, Rønnekleiv OK. Suppression subtractive hybridization and microarray identification of estrogen-regulated hypothalamic genes. Neurochem Res. 2004 Jun; 29(6):1189-200. PMID: 15176476.
    Citations: 20     Fields:    Translation:AnimalsCells
  74. Kelly MJ, Qiu J, Rønnekleiv OK. Estrogen modulation of G-protein-coupled receptor activation of potassium channels in the central nervous system. Ann N Y Acad Sci. 2003 Dec; 1007:6-16. PMID: 14993035.
    Citations: 33     Fields:    Translation:HumansAnimals
  75. Qiu J, Bosch MA, Tobias SC, Grandy DK, Scanlan TS, Ronnekleiv OK, Kelly MJ. Rapid signaling of estrogen in hypothalamic neurons involves a novel G-protein-coupled estrogen receptor that activates protein kinase C. J Neurosci. 2003 Oct 22; 23(29):9529-40. PMID: 14573532.
    Citations: 180     Fields:    Translation:AnimalsCells
  76. Slugg RM, Zheng SX, Fang Y, Kelly MJ, Rønnekleiv OK. Baclofen inhibits guinea pig magnocellular neurones via activation of an inwardly rectifying K+ conductance. J Physiol. 2003 Aug 15; 551(Pt 1):295-308. PMID: 12813153.
    Citations: 11     Fields:    Translation:AnimalsCells
  77. Ibrahim N, Bosch MA, Smart JL, Qiu J, Rubinstein M, Rønnekleiv OK, Low MJ, Kelly MJ. Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels. Endocrinology. 2003 Apr; 144(4):1331-40. PMID: 12639916.
    Citations: 115     Fields:    Translation:AnimalsCells
  78. Jamali K, Naylor BR, Kelly MJ, Rønnekleiv OK. Effect of 17beta-estradiol on mRNA expression of large- conductance, voltage-dependent, and calcium-activated potassium channel alpha and beta subunits in guinea pig. Endocrine. 2003 Apr; 20(3):227-37. PMID: 12721501.
    Citations: 9     Fields:    Translation:AnimalsCells
  79. Kelly MJ, Wagner EJ. GnRH neurons and episodic bursting activity. Trends Endocrinol Metab. 2002 Dec; 13(10):409-10. PMID: 12431832.
    Citations: 20     Fields:    Translation:Cells
  80. Kelly MJ, Qiu J, Wagner EJ, Rønnekleiv OK. Rapid effects of estrogen on G protein-coupled receptor activation of potassium channels in the central nervous system (CNS). J Steroid Biochem Mol Biol. 2002 Dec; 83(1-5):187-93. PMID: 12650715.
    Citations: 32     Fields:    Translation:AnimalsCells
  81. Kelly MJ, Rønnekleiv OK, Ibrahim N, Lagrange AH, Wagner EJ. Estrogen modulation of K(+) channel activity in hypothalamic neurons involved in the control of the reproductive axis. Steroids. 2002 May; 67(6):447-56. PMID: 11960620.
    Citations: 24     Fields:    Translation:AnimalsCells
  82. Bosch MA, Kelly MJ, Rønnekleiv OK. Distribution, neuronal colocalization, and 17beta-E2 modulation of small conductance calcium-activated K(+) channel (SK3) mRNA in the guinea pig brain. Endocrinology. 2002 Mar; 143(3):1097-107. PMID: 11861537.
    Citations: 29     Fields:    Translation:AnimalsCells
  83. Bosch MA, Kelly MJ, Rønnekleiv OK. Distribution, Neuronal Colocalization, and 17ß-E2 Modulation of Small Conductance Calcium-Activated K+ Channel (SK3) mRNA in the Guinea Pig Brain. Endocrinology. 2002 Mar 01; 143(3):1097-1107. PMID: 28201389.
    Citations:    
  84. Chinman G, Kelly M, Borus J. Teaching residents the reality of current mental health care. Harv Rev Psychiatry. 2002 Jan-Feb; 10(1):56-8. PMID: 11751647.
    Citations:    Fields:    Translation:Humans
  85. Wagner EJ, Rønnekleiv OK, Kelly MJ. The noradrenergic inhibition of an apamin-sensitive, small-conductance Ca2+-activated K+ channel in hypothalamic gamma-aminobutyric acid neurons: pharmacology, estrogen sensitivity, and relevance to the control of the reproductive axis. J Pharmacol Exp Ther. 2001 Oct; 299(1):21-30. PMID: 11561059.
    Citations: 20     Fields:    Translation:AnimalsCells
  86. Kelly MJ, Levin ER. Rapid actions of plasma membrane estrogen receptors. Trends Endocrinol Metab. 2001 May-Jun; 12(4):152-6. PMID: 11295570.
    Citations: 126     Fields:    Translation:HumansAnimalsCells
  87. Wagner EJ, Ronnekleiv OK, Bosch MA, Kelly MJ. Estrogen biphasically modifies hypothalamic GABAergic function concomitantly with negative and positive control of luteinizing hormone release. J Neurosci. 2001 Mar 15; 21(6):2085-93. PMID: 11245692.
    Citations: 33     Fields:    Translation:AnimalsCells
  88. Wagner EJ, Reyes-Vazquez C, Ronnekleiv OK, Kelly MJ. The role of intrinsic and agonist-activated conductances in determining the firing patterns of preoptic area neurons in the guinea pig. Brain Res. 2000 Oct 06; 879(1-2):29-41. PMID: 11011003.
    Citations: 6     Fields:    Translation:AnimalsCells
  89. Slugg RM, Hayward MD, Ronnekleiv OK, Low MJ, Kelly MJ. Effect of the mu-opioid agonist DAMGO on medial basal hypothalamic neurons in beta-endorphin knockout mice. Neuroendocrinology. 2000 Oct; 72(4):208-17. PMID: 11070424.
    Citations: 4     Fields:    Translation:AnimalsCells
  90. Wagner EJ, Bosch MA, Kelly MJ, Rønnekleiv OK. A powerful GABA(B) receptor-mediated inhibition of GABAergic neurons in arcuate nucleus. Neuroreport. 1999 Aug 20; 10(12):2681-7. PMID: 10574392.
    Citations: 7     Fields:    Translation:AnimalsCells
  91. Slugg RM, Rønnekleiv OK, Grandy DK, Kelly MJ. Activation of an inwardly rectifying K+ conductance by orphanin-FQ/nociceptin in vasopressin-containing neurons. Neuroendocrinology. 1999 May; 69(5):385-96. PMID: 10343180.
    Citations: 5     Fields:    Translation:AnimalsCells
  92. Kelly MJ, Lagrange AH, Wagner EJ, Rønnekleiv OK. Rapid effects of estrogen to modulate G protein-coupled receptors via activation of protein kinase A and protein kinase C pathways. Steroids. 1999 Jan-Feb; 64(1-2):64-75. PMID: 10323674.
    Citations: 38     Fields:    Translation:AnimalsCells
  93. Wagner EJ, Bosch MA, Kelly MJ, Rønnekleiv K. A powerful GABA(B) receptor-mediated inhibition of GABAergic neurons in the arcuate nucleus. Neuroreport. 1998 Dec 21; 9(18):4171-7. PMID: 9926869.
    Citations:    Fields:    Translation:AnimalsCells
  94. Wagner EJ, Rønnekleiv OK, Kelly MJ. Protein kinase A maintains cellular tolerance to mu opioid receptor agonists in hypothalamic neurosecretory cells with chronic morphine treatment: convergence on a common pathway with estrogen in modulating mu opioid receptor/effector coupling. J Pharmacol Exp Ther. 1998 Jun; 285(3):1266-73. PMID: 9618432.
    Citations: 5     Fields:    Translation:Animals
  95. Cunningham MJ, Fang Y, Selley DE, Kelly MJ. mu-Opioid agonist-stimulated [35S]GTPgammaS binding in guinea pig hypothalamus: effects of estrogen. Brain Res. 1998 Apr 27; 791(1-2):341-6. PMID: 9593984.
    Citations: 10     Fields:    Translation:Animals
  96. Fang Y, Kelly MJ, Rønnekleiv OK. Proopiomelanocortin (POMC) mRNA expression: distribution and region-specific down-regulation by chronic morphine in female guinea pig hypothalamus. Brain Res Mol Brain Res. 1998 Mar 30; 55(1):1-8. PMID: 9645954.
    Citations: 7     Fields:    Translation:AnimalsCells
  97. Wagner EJ, Rønnekleiv OK, Grandy DK, Kelly MJ. The peptide orphanin FQ inhibits beta-endorphin neurons and neurosecretory cells in the hypothalamic arcuate nucleus by activating an inwardly-rectifying K+ conductance. Neuroendocrinology. 1998 Feb; 67(2):73-82. PMID: 9508037.
    Citations: 28     Fields:    Translation:AnimalsCells
  98. Lagrange AH, Ronnekleiv OK, Kelly MJ. Modulation of G protein-coupled receptors by an estrogen receptor that activates protein kinase A. Mol Pharmacol. 1997 Apr; 51(4):605-12. PMID: 9106625.
    Citations: 49     Fields:    Translation:AnimalsCells
  99. Wagner EJ, Zhang G, Lagrange AH, Rønnekleiv OK, Kelly MJ. Tolerance to mu-opioid receptor agonists but not cross-tolerance to gamma-aminobutyric acid(B) receptor agonists in arcuate A12 dopamine neurons with chronic morphine treatment. J Pharmacol Exp Ther. 1997 Feb; 280(2):1057-64. PMID: 9023324.
    Citations:    Fields:    Translation:AnimalsCells
  100. Rønnekleiv OK, Bosch MA, Cunningham MJ, Wagner EJ, Grandy DK, Kelly MJ. Downregulation of mu-opioid receptor mRNA in the mediobasal hypothalamus of the female guinea pig following morphine treatment. Neurosci Lett. 1996 Sep 27; 216(2):129-32. PMID: 8904800.
    Citations: 3     Fields:    Translation:AnimalsCells
  101. Lagrange AH, Wagner EJ, Rønnekleiv OK, Kelly MJ. Estrogen rapidly attenuates a GABAB response in hypothalamic neurons. Neuroendocrinology. 1996 Aug; 64(2):114-23. PMID: 8857605.
    Citations: 25     Fields:    Translation:AnimalsCells
  102. Zhang G, Lagrange AH, Rønnekleiv OK, Kelly MJ. Tolerance of hypothalamic beta-endorphin neurons to mu-opioid receptor activation after chronic morphine. J Pharmacol Exp Ther. 1996 Apr; 277(1):551-8. PMID: 8613967.
    Citations: 4     Fields:    Translation:Animals
  103. Lagrange AH, Rønnekleiv OK, Kelly MJ. Estradiol-17 beta and mu-opioid peptides rapidly hyperpolarize GnRH neurons: a cellular mechanism of negative feedback? Endocrinology. 1995 May; 136(5):2341-4. PMID: 7720682.
    Citations: 51     Fields:    Translation:AnimalsCells
  104. Bunzow JR, Zhang G, Bouvier C, Saez C, Ronnekleiv OK, Kelly MJ, Grandy DK. Characterization and distribution of a cloned rat mu-opioid receptor. J Neurochem. 1995 Jan; 64(1):14-24. PMID: 7798908.
    Citations: 12     Fields:    Translation:AnimalsCells
  105. Lagrange AH, Ronnekleiv OK, Kelly MJ. The potency of mu-opioid hyperpolarization of hypothalamic arcuate neurons is rapidly attenuated by 17 beta-estradiol. J Neurosci. 1994 Oct; 14(10):6196-204. PMID: 7931572.
    Citations: 23     Fields:    Translation:AnimalsCells
  106. Thornton JE, Loose MD, Kelly MJ, Rönnekleiv OK. Effects of estrogen on the number of neurons expressing beta-endorphin in the medial basal hypothalamus of the female guinea pig. J Comp Neurol. 1994 Mar 01; 341(1):68-77. PMID: 8006224.
    Citations: 27     Fields:    Translation:AnimalsCells
  107. Erickson KR, Ronnekleiv OK, Kelly MJ. Role of a T-type calcium current in supporting a depolarizing potential, damped oscillations, and phasic firing in vasopressinergic guinea pig supraoptic neurons. Neuroendocrinology. 1993 May; 57(5):789-800. PMID: 8413816.
    Citations: 24     Fields:    Translation:AnimalsCells
  108. Erickson KR, Ronnekleiv OK, Kelly MJ. Electrophysiology of guinea-pig supraoptic neurones: role of a hyperpolarization-activated cation current in phasic firing. J Physiol. 1993 Jan; 460:407-25. PMID: 8487202.
    Citations: 22     Fields:    Translation:AnimalsCells
  109. Kelly MJ, Loose MD, Ronnekleiv OK. Estrogen suppresses mu-opioid- and GABAB-mediated hyperpolarization of hypothalamic arcuate neurons. J Neurosci. 1992 Jul; 12(7):2745-50. PMID: 1319480.
    Citations: 35     Fields:    Translation:AnimalsCells
  110. Loose MD, Ronnekleiv OK, Kelly MJ. Neurons in the rat arcuate nucleus are hyperpolarized by GABAB and mu-opioid receptor agonists: evidence for convergence at a ligand-gated potassium conductance. Neuroendocrinology. 1991 Dec; 54(6):537-44. PMID: 1664497.
    Citations: 6     Fields:    Translation:AnimalsCells
  111. Ma YJ, Kelly MJ, Rönnekleiv OK. Pro-gonadotropin-releasing hormone (ProGnRH) and GnRH content in the preoptic area and the basal hypothalamus of anterior medial preoptic nucleus/suprachiasmatic nucleus-lesioned persistent estrous rats. Endocrinology. 1990 Dec; 127(6):2654-64. PMID: 2249619.
    Citations: 8     Fields:    Translation:AnimalsCells
  112. Loose MD, Ronnekleiv OK, Kelly MJ. Membrane properties and response to opioids of identified dopamine neurons in the guinea pig hypothalamus. J Neurosci. 1990 Nov; 10(11):3627-34. PMID: 1977895.
    Citations: 10     Fields:    Translation:AnimalsCells
  113. Rønnekleiv OK, Loose MD, Erickson KR, Kelly MJ. A method for immunocytochemical identification of biocytin-labeled neurons following intracellular recording. Biotechniques. 1990 Oct; 9(4):432-8. PMID: 1979496.
    Citations: 8     Fields:    Translation:AnimalsCells
  114. Kelly MJ, Loose MD, Ronnekleiv OK. Opioids hyperpolarize beta-endorphin neurons via mu-receptor activation of a potassium conductance. Neuroendocrinology. 1990 Sep; 52(3):268-75. PMID: 2170854.
    Citations: 16     Fields:    Translation:AnimalsCells
  115. Erickson KR, Ronnekleiv OK, Kelly MJ. Inward Rectification (I) in Immunocytochemically-ldentified Vasopressin and Oxytocin Neurons of Guinea-Pig Supraoptic Nucleus. J Neuroendocrinol. 1990 Jun 01; 2(3):261-5. PMID: 19215344.
    Citations: 4     Fields:    
  116. Loose MD, Kelly MJ. Opioids act at mu-receptors to hyperpolarize arcuate neurons via an inwardly rectifying potassium conductance. Brain Res. 1990 Apr 09; 513(1):15-23. PMID: 2161696.
    Citations: 12     Fields:    Translation:Animals
  117. Roselli CE, Kelly MJ, Ronnekleiv OK. Testosterone regulates progonadotropin-releasing hormone levels in the preoptic area and basal hypothalamus of the male rat. Endocrinology. 1990 Feb; 126(2):1080-6. PMID: 2404741.
    Citations: 6     Fields:    Translation:Animals
  118. Condon TP, Ronnekleiv OK, Kelly MJ. Estrogen modulation of the alpha-1-adrenergic response of hypothalamic neurons. Neuroendocrinology. 1989 Jul; 50(1):51-8. PMID: 2547176.
    Citations: 10     Fields:    Translation:AnimalsCells
  119. Loose MD, Kelly MJ. Opioid inhibition of spontaneously active neurons of the rat arcuate nucleus in vitro. Brain Res Bull. 1989 May; 22(5):819-23. PMID: 2548677.
    Citations: 1     Fields:    Translation:Animals
  120. Kelly MJ, Garrett J, Bosch MA, Roselli CE, Douglass J, Adelman JP, Ronnekleiv OK. Effects of ovariectomy on GnRH mRNA, proGnRH and GnRH levels in the preoptic hypothalamus of the female rat. Neuroendocrinology. 1989 Jan; 49(1):88-97. PMID: 2469986.
    Citations: 6     Fields:    Translation:AnimalsCells
  121. Ronnekleiv OK, Kelly MJ. Plasma prolactin and luteinizing hormone profiles during the estrous cycle of the female rat: effects of surgically induced persistent estrus. Neuroendocrinology. 1988 Feb; 47(2):133-41. PMID: 3344065.
    Citations: 10     Fields:    Translation:Animals
  122. Condon TP, Dykshoorn-Bosch MA, Kelly MJ. Episodic luteinizing-hormone release in the ovariectomized female guinea pig: rapid inhibition by estrogen. Biol Reprod. 1988 Feb; 38(1):121-6. PMID: 3284595.
    Citations: 6     Fields:    Translation:Animals
  123. Ronnekleiv OK, Adelman JP, Weber E, Herbert E, Kelly MJ. Immunohistochemical demonstration of proGnRH and GnRH in the preoptic-basal hypothalamus of the primate. Neuroendocrinology. 1987 Jun; 45(6):518-21. PMID: 3302746.
    Citations: 2     Fields:    Translation:Animals
  124. Ronnekleiv OK, Kelly MJ. Luteinizing hormone-releasing hormone neuronal system during the estrous cycle of the female rat: effects of surgically induced persistent estrus. Neuroendocrinology. 1986; 43(5):564-76. PMID: 3528898.
    Citations: 10     Fields:    Translation:AnimalsCells
  125. Kelly MJ, Condon TP, Levine JE, Ronnekleiv OK. Combined electrophysiological, immunocytochemical and peptide release measurements in the hypothalamic slice. Brain Res. 1985 Oct 21; 345(2):264-70. PMID: 3899282.
    Citations: 5     Fields:    Translation:Animals
  126. Ellinwood WE, Ronnekleiv OK, Kelly MJ, Resko JA. A new antiserum with conformational specificity for LHRH: usefulness for radioimmunoassay and immunocytochemistry. Peptides. 1985 Jan-Feb; 6(1):45-52. PMID: 3887335.
    Citations: 4     Fields:    Translation:AnimalsCells
  127. Kelly MJ, Ronnekleiv OK, Eskay RL. Identification of estrogen-responsive LHRH neurons in the guinea pig hypothalamus. Brain Res Bull. 1984 Apr; 12(4):399-407. PMID: 6203621.
    Citations: 32     Fields:    Translation:Animals
  128. Rønnekleiv OK, Kelly MJ, Eskay RL. Distribution of immunoreactive substance P neurons in the hypothalamus and pituitary of the rhesus monkey. J Comp Neurol. 1984 Mar 20; 224(1):51-9. PMID: 6201513.
    Citations: 7     Fields:    Translation:AnimalsCells
  129. Rønnekleiv OK, Kelly MJ. Distribution of substance P neurons in the epithalamus of the rat: an immunohistochemical investigation. J Pineal Res. 1984; 1(4):355-70. PMID: 6085878.
    Citations: 6     Fields:    Translation:AnimalsCells
  130. Kelly MJ, Ronnekleiv OK, Eskay RL. Immunocytochemical localization of luteinizing hormone-releasing hormone in neurons in the medial basal hypothalamus of the female rat. Exp Brain Res. 1982; 48(1):97-106. PMID: 6183141.
    Citations: 4     Fields:    Translation:AnimalsCells
  131. Kelly MJ, Kuhnt U, Wuttke W. Electrophysiological and morphological properties of E2-responsive neurons. Exp Brain Res. 1981; Suppl 3:294-308. PMID: 7195824.
    Citations: 1     Fields:    Translation:AnimalsCells
  132. Rønnekleiv OK, Kelly MJ, Wuttke W. Single unit recordings in the rat pineal gland: evidence for habenulo-pineal neural connections. Exp Brain Res. 1980; 39(2):187-92. PMID: 7398816.
    Citations: 14     Fields:    Translation:AnimalsCells
  133. Kelly MJ, Kuhnt U, Wuttke W. Hyperpolarization of hypothalamic parvocellular neurons by 17 beta-estradiol and their identification through intracellular staining with procion yellow. Exp Brain Res. 1980; 40(4):440-7. PMID: 6254791.
    Citations: 11     Fields:    Translation:AnimalsCells
  134. Kuhnt U, Kelly MJ, Schaumberg R. Transynaptic transport of procion yellow in the central nervous system. Exp Brain Res. 1979 Apr 02; 35(2):371-85. PMID: 220071.
    Citations: 4     Fields:    Translation:AnimalsCells
  135. Kelly MJ, Kuhnt U, Wuttke W. Morphological features of physiologically identified hypothalamic neurons as revealed by intracellular marking. Exp Brain Res. 1979 Jan 02; 34(1):107-16. PMID: 759218.
    Citations: 5     Fields:    Translation:AnimalsCells
  136. Moss RL, Kelly MJ, Dudley CA. Chemosensitivity of hypophysiotropic neurons to the microelectrophoresis of biogenic amines. Brain Res. 1978 Jan 06; 139(1):141-52. PMID: 23205.
    Citations: 6     Fields:    Translation:AnimalsCells
  137. Kelly MJ, Moss RL, Dudley CA. The effect of ovariectomy on the responsiveness of preoptic-septal neurons to microelectrophoresed estrogen. Neuroendocrinology. 1978; 25(4):204-11. PMID: 652126.
    Citations: 8     Fields:    Translation:AnimalsCells
  138. Kelly MJ, Moss RL, Dudley CA, Fawcett CP. The specificity of the response of preoptic-septal area neurons to estrogen: 17alpha-estradiol versus 17beta-estradiol and the response of extrahypothalamic neurons. Exp Brain Res. 1977 Oct 24; 30(1):43-52. PMID: 563340.
    Citations: 23     Fields:    Translation:AnimalsCells
  139. Kelly MJ, Moss RL, Dudley CA. Differential sensitivity of preoptic-septal neurons to microelectrophoresed estrogen during the estrous cycle. Brain Res. 1976 Sep 10; 114(1):152-7. PMID: 986858.
    Citations: 55     Fields:    Translation:AnimalsCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Kelly's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (455)
Explore
_
Co-Authors (3)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.