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Alan D Michelson, M.B.,B.S.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Charnigo RJ, Beidler D, Rybin D, Pittman DD, Tan B, Howard J, Michelson AD, Frelinger AL, Clarke N. PF-04447943, a Phosphodiesterase 9A Inhibitor, in Stable Sickle Cell Disease Patients: A Phase Ib Randomized, Placebo-Controlled Study. Clin Transl Sci. 2018 Dec 31. PMID: 30597771.
    Citations:    Fields:    
  2. Smolensky Koganov E, Michelson AD, Yanachkov IB, Yanachkova MI, Wright GE, Przyklenk K, Frelinger AL. Publisher Correction: GLS-409, an Antagonist of Both P2Y1 and P2Y12, Potently Inhibits Canine Coronary Artery Thrombosis and Reversibly Inhibits Human Platelet Activation. Sci Rep. 2018 Nov 29; 8(1):17580. PMID: 30498241.
    Citations:    Fields:    
  3. Smolensky Koganov E, Michelson AD, Yanachkov IB, Yanachkova MI, Wright GE, Przyklenk K, Frelinger AL. GLS-409, an Antagonist of Both P2Y1 and P2Y12, Potently Inhibits Canine Coronary Artery Thrombosis and Reversibly Inhibits Human Platelet Activation. Sci Rep. 2018 Sep 28; 8(1):14529. PMID: 30266987.
    Citations:    Fields:    
  4. Michelson AD, Smolensky Koganov E, Forde EE, Carmichael SL, Frelinger AL. Avatrombopag increases platelet count but not platelet activation in patients with thrombocytopenia resulting from liver disease. J Thromb Haemost. 2018 Sep 28. PMID: 30264918.
    Citations:    Fields:    
  5. Frelinger AL, Gerrits AJ, Neculaes VB, Gremmel T, Torres AS, Caiafa A, Carmichael SL, Michelson AD. Tunable activation of therapeutic platelet-rich plasma by pulse electric field: Differential effects on clot formation, growth factor release, and platelet morphology. PLoS One. 2018; 13(9):e0203557. PMID: 30256831.
    Citations:    Fields:    
  6. Blair TA, Michelson AD, Frelinger AL. Mass Cytometry Reveals Distinct Platelet Subtypes in Healthy Subjects and Novel Alterations in Surface Glycoproteins in Glanzmann Thrombasthenia. Sci Rep. 2018 Jul 09; 8(1):10300. PMID: 29985398.
    Citations:    Fields:    
  7. Gremmel T, Michelson AD, Frelinger AL, Bhatt DL. Novel aspects of antiplatelet therapy in cardiovascular disease. Res Pract Thromb Haemost. 2018 Jul; 2(3):439-449. PMID: 30046748.
    Citations:    
  8. Gerrits AJ, Jakubowski JA, Michelson AD, Frelinger AL. Incomplete reversibility of platelet inhibition following prolonged exposure to ticagrelor: reply. J Thromb Haemost. 2018 Mar; 16(3):607-608. PMID: 29314666.
    Citations:    Fields:    
  9. Frelinger AL, Grace RF, Gerrits AJ, Carmichael SL, Forde EE, Michelson AD. Platelet Function in ITP, Independent of Platelet Count, Is Consistent Over Time and Is Associated with Both Current and Subsequent Bleeding Severity. Thromb Haemost. 2018 Jan; 118(1):143-151. PMID: 29304534.
    Citations: 1     Fields:    
  10. Michelson AD. Immature platelet fraction in immune thrombocytopenia: Useful in diagnosis but does it predict bleeding? Pediatr Blood Cancer. 2018 Feb; 65(2). PMID: 28988440.
    Citations:    Fields:    
  11. Haynes RL, Frelinger AL, Giles EK, Goldstein RD, Tran H, Kozakewich HP, Haas EA, Gerrits AJ, Mena OJ, Trachtenberg FL, Paterson DS, Berry GT, Adeli K, Kinney HC, Michelson AD. High serum serotonin in sudden infant death syndrome. Proc Natl Acad Sci U S A. 2017 07 18; 114(29):7695-7700. PMID: 28674018.
    Citations: 3     Fields:    Translation:Humans
  12. Michelson AD, Bhatt DL. How I use laboratory monitoring of antiplatelet therapy. Blood. 2017 08 10; 130(6):713-721. PMID: 28600334.
    Citations: 3     Fields:    Translation:HumansCells
  13. Gerrits AJ, Jakubowski JA, Sugidachi A, Michelson AD, Frelinger AL. Incomplete reversibility of platelet inhibition following prolonged exposure to ticagrelor. J Thromb Haemost. 2017 05; 15(5):858-867. PMID: 28092426.
    Citations: 2     Fields:    Translation:HumansCells
  14. Gerrits AJ, Frelinger AL, Michelson AD. Whole Blood Analysis of Leukocyte-Platelet Aggregates. Curr Protoc Cytom. 2016 10 10; 78:6.15.1-6.15.10. PMID: 27723089.
    Citations: 2     Fields:    Translation:HumansCells
  15. Frelinger AL, Gerrits AJ, Garner AL, Torres AS, Caiafa A, Morton CA, Berny-Lang MA, Carmichael SL, Neculaes VB, Michelson AD. Modification of Pulsed Electric Field Conditions Results in Distinct Activation Profiles of Platelet-Rich Plasma. PLoS One. 2016; 11(8):e0160933. PMID: 27556645.
    Citations: 7     Fields:    Translation:HumansCells
  16. Jain A, van der Meer AD, Papa AL, Barrile R, Lai A, Schlechter BL, Otieno MA, Louden CS, Hamilton GA, Michelson AD, Frelinger AL, Ingber DE. Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium. Biomed Microdevices. 2016 08; 18(4):73. PMID: 27464497; PMCID: PMC4963439.
    Citations: 8     Fields:    Translation:HumansCells
  17. Carreras ET, Hochholzer W, Frelinger AL, Nordio F, O'Donoghue ML, Wiviott SD, Angiolillo DJ, Michelson AD, Sabatine MS, Mega JL. Diabetes mellitus, CYP2C19 genotype, and response to escalating doses of clopidogrel. Insights from the ELEVATE-TIMI 56 Trial. Thromb Haemost. 2016 07 04; 116(1):69-77. PMID: 27009617.
    Citations: 4     Fields:    Translation:Humans
  18. Gremmel T, Frelinger AL, Michelson AD. Platelet Physiology. Semin Thromb Hemost. 2016 Apr; 42(3):191-204. PMID: 26926581.
    Citations: 8     Fields:    Translation:HumansCells
  19. Gremmel T, Yanachkov IB, Yanachkova MI, Wright GE, Wider J, Undyala VV, Michelson AD, Frelinger AL, Przyklenk K. Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):501-9. PMID: 26743169; PMCID: PMC4767596.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  20. Gremmel T, Michelson AD, Frelinger AL. In Vivo and protease-activated receptor-1-mediated platelet activation in patients presenting for cardiac catheterization. Platelets. 2016 Jun; 27(4):308-16. PMID: 26556638.
    Citations: 2     Fields:    Translation:HumansCells
  21. Yanachkov IB, Chang H, Yanachkova MI, Dix EJ, Berny-Lang MA, Gremmel T, Michelson AD, Wright GE, Frelinger AL. New highly active antiplatelet agents with dual specificity for platelet P2Y1 and P2Y12 adenosine diphosphate receptors. Eur J Med Chem. 2016 Jan 01; 107:204-18. PMID: 26588064; PMCID: PMC4674339.
    Citations: 4     Fields:    Translation:HumansAnimals
  22. Brun C, Daali Y, Combescure C, Zufferey A, Michelson AD, Fontana P, Reny JL, Frelinger AL. Aspirin response: Differences in serum thromboxane B2 levels between clinical studies. Platelets. 2016; 27(3):196-202. PMID: 26270593.
    Citations: 2     Fields:    Translation:HumansCells
  23. Gremmel T, Frelinger AL, Michelson AD. Soluble CD40 Ligand in Aspirin-Treated Patients Undergoing Cardiac Catheterization. PLoS One. 2015; 10(8):e0134599. PMID: 26237513; PMCID: PMC4523196.
    Citations: 1     Fields:    Translation:Humans
  24. Gerrits AJ, Leven EA, Frelinger AL, Brigstocke SL, Berny-Lang MA, Mitchell WB, Revel-Vilk S, Tamary H, Carmichael SL, Barnard MR, Michelson AD, Bussel JB. Effects of eltrombopag on platelet count and platelet activation in Wiskott-Aldrich syndrome/X-linked thrombocytopenia. Blood. 2015 Sep 10; 126(11):1367-78. PMID: 26224646; PMCID: PMC4729539.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  25. Frelinger AL, Grace RF, Gerrits AJ, Berny-Lang MA, Brown T, Carmichael SL, Neufeld EJ, Michelson AD. Platelet function tests, independent of platelet count, are associated with bleeding severity in ITP. Blood. 2015 Aug 13; 126(7):873-9. PMID: 26138687; PMCID: PMC4536541.
    Citations: 13     Fields:    Translation:HumansCells
  26. Frelinger AL, Torres AS, Caiafa A, Morton CA, Berny-Lang MA, Gerrits AJ, Carmichael SL, Neculaes VB, Michelson AD. Platelet-rich plasma stimulated by pulse electric fields: Platelet activation, procoagulant markers, growth factor release and cell proliferation. Platelets. 2016; 27(2):128-35. PMID: 26030682.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  27. Sakurai Y, Fitch-Tewfik JL, Qiu Y, Ahn B, Myers DR, Tran R, Fay ME, Ding L, Spearman PW, Michelson AD, Flaumenhaft R, Lam WA. Platelet geometry sensing spatially regulates a-granule secretion to enable matrix self-deposition. Blood. 2015 Jul 23; 126(4):531-8. PMID: 25964667; PMCID: PMC4513253.
    Citations: 2     Fields:    Translation:HumansCells
  28. McCrindle BW, Li JS, Manlhiot C, Tweddell JS, Giglia TM, Massicotte MP, Monagle P, Krishnamurthy R, Mahaffey KW, Michelson AD, Verdun N, Almond CS, Newburger JW, Brandão LR, Esmon CT, Manco-Johnson MJ, Ichord R, Ortel TL, Chan AK, Portman R, Rose M, Strony J, Kaltman JR. Challenges and priorities for research: a report from the National Heart, Lung, and Blood Institute (NHLBI)/National Institutes of Health (NIH) Working Group on thrombosis in pediatric cardiology and congenital heart disease. Circulation. 2014 Sep 30; 130(14):1192-203. PMID: 25266860.
    Citations: 2     Fields:    Translation:Humans
  29. Torres AS, Caiafa A, Garner AL, Klopman S, LaPlante N, Morton C, Conway K, Michelson AD, Frelinger AL, Neculaes VB. Platelet activation using electric pulse stimulation: growth factor profile and clinical implications. J Trauma Acute Care Surg. 2014 Sep; 77(3 Suppl 2):S94-S100. PMID: 25159369.
    Citations: 5     Fields:    Translation:HumansAnimals
  30. Hochholzer W, Ruff CT, Mesa RA, Mattimore JF, Cyr JF, Lei L, Frelinger AL, Michelson AD, Berg DD, Angiolillo DJ, O'Donoghue ML, Sabatine MS, Mega JL. Variability of individual platelet reactivity over time in patients treated with clopidogrel: insights from the ELEVATE-TIMI 56 trial. J Am Coll Cardiol. 2014 Jul 29; 64(4):361-8. PMID: 25060370.
    Citations: 9     Fields:    Translation:Humans
  31. Berny-Lang MA, Darling CE, Frelinger AL, Barnard MR, Smith CS, Michelson AD. Do immature platelet levels in chest pain patients presenting to the emergency department aid in the diagnosis of acute coronary syndrome? Int J Lab Hematol. 2015 Feb; 37(1):112-9. PMID: 24806286; PMCID: PMC4225001.
    Citations: 1     Fields:    Translation:HumansCells
  32. Chang H, Yanachkov IB, Dix EJ, Yanachkova M, Li Y, Barnard MR, Wright GE, Michelson AD, Frelinger AL. Antiplatelet activity, P2Y1 and P2Y12 inhibition, and metabolism in plasma of stereoisomers of diadenosine 5',5'?-P¹ ,P4-dithio-P²,P³-chloromethylenetetraphosphate. PLoS One. 2014; 9(4):e94780. PMID: 24722456; PMCID: PMC3983250.
    Citations: 6     Fields:    Translation:Humans
  33. Darling CE, Sala Mercado JA, Quiroga-Castro W, Tecco GF, Zelaya FR, Conci EC, Sala JP, Smith CS, Michelson AD, Whittaker P, Welch RD, Przyklenk K. Point-of-care assessment of platelet reactivity in the emergency department may facilitate rapid rule-out of acute coronary syndromes: a prospective cohort pilot feasibility study. BMJ Open. 2014 Jan 17; 4(1):e003883. PMID: 24441051; PMCID: PMC3902349.
    Citations: 1     Fields:    Translation:Humans
  34. Siller-Matula JM, Trenk D, Krähenbühl S, Michelson AD, Delle-Karth G. Clinical implications of drug-drug interactions with P2Y12 receptor inhibitors. J Thromb Haemost. 2014 Jan; 12(1):2-13. PMID: 24406062.
    Citations: 9     Fields:    Translation:Humans
  35. Chang H, Shih LY, Michelson AD, Dunn P, Frelinger AL, Wang PN, Kuo MC, Lin TL, Wu JH, Tang TC. Clinical and laboratory significance of defective P2Y(12) pathway function in patients with myeloproliferative neoplasms: a pilot study. Acta Haematol. 2013; 130(3):181-7. PMID: 23751441.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  36. Smith BW, Rozelle SS, Leung A, Ubellacker J, Parks A, Nah SK, French D, Gadue P, Monti S, Chui DH, Steinberg MH, Frelinger AL, Michelson AD, Theberge R, McComb ME, Costello CE, Kotton DN, Mostoslavsky G, Sherr DH, Murphy GJ. The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. Blood. 2013 Jul 18; 122(3):376-85. PMID: 23723449.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  37. Berny-Lang MA, Jakubowski JA, Sugidachi A, Barnard MR, Michelson AD, Frelinger AL. P2Y12 receptor blockade augments glycoprotein IIb-IIIa antagonist inhibition of platelet activation, aggregation, and procoagulant activity. J Am Heart Assoc. 2013 May 15; 2(3):e000026. PMID: 23676293; PMCID: PMC3698756.
    Citations: 3     Fields:    Translation:HumansCells
  38. Psaila B, Bussel JB, Frelinger AL, Michelson AD. Differences in platelet function in patients with acute myeloid leukemia and myelodysplasia compared to equally thrombocytopenic patients with immune thrombocytopenia: a reply to a rebuttal. J Thromb Haemost. 2013 May; 11(5):1002-3. PMID: 23496753.
    Citations:    Fields:    Translation:HumansCells
  39. Cattaneo M, Cerletti C, Harrison P, Hayward CP, Kenny D, Nugent D, Nurden P, Rao AK, Schmaier AH, Watson SP, Lussana F, Pugliano MT, Michelson AD. Recommendations for the Standardization of Light Transmission Aggregometry: A Consensus of the Working Party from the Platelet Physiology Subcommittee of SSC/ISTH. J Thromb Haemost. 2013 Apr 10. PMID: 23574625.
    Citations: 43     Fields:    
  40. Frelinger AL, Jakubowski JA, Brooks JK, Carmichael SL, Berny-Lang MA, Barnard MR, Heeney MM, Michelson AD. Platelet activation and inhibition in sickle cell disease (pains) study. Platelets. 2014; 25(1):27-35. PMID: 23469943.
    Citations: 12     Fields:    Translation:HumansCells
  41. Frelinger AL, Bhatt DL, Lee RD, Mulford DJ, Wu J, Nudurupati S, Nigam A, Lampa M, Brooks JK, Barnard MR, Michelson AD. Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in platelet function. J Am Coll Cardiol. 2013 Feb 26; 61(8):872-9. PMID: 23333143.
    Citations: 33     Fields:    Translation:Humans
  42. Michelson AD. Gray platelet syndrome. Blood. 2013 Jan 10; 121(2):250. PMID: 23427340.
    Citations: 1     Fields:    Translation:Humans
  43. Chang H, Yanachkov IB, Dix EJ, Li YF, Barnard MR, Wright GE, Michelson AD, Frelinger AL. Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation. J Thromb Haemost. 2012 Dec; 10(12):2573-80. PMID: 23083103.
    Citations: 7     Fields:    Translation:HumansCells
  44. Fuster V, Bhatt DL, Califf RM, Michelson AD, Sabatine MS, Angiolillo DJ, Bates ER, Cohen DJ, Coller BS, Furie B, Hulot JS, Mann KG, Mega JL, Musunuru K, O'Donnell CJ, Price MJ, Schneider DJ, Simon DI, Weitz JI, Williams MS, Hoots WK, Rosenberg YD, Hasan AA. Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group. Circulation. 2012 Sep 25; 126(13):1645-62. PMID: 23008471; PMCID: PMC4086864.
    Citations: 7     Fields:    Translation:Humans
  45. Peters CG, Michelson AD, Flaumenhaft R. Granule exocytosis is required for platelet spreading: differential sorting of a-granules expressing VAMP-7. Blood. 2012 Jul 05; 120(1):199-206. PMID: 22589474; PMCID: PMC3390958.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  46. Frelinger AL, Lee RD, Mulford DJ, Wu J, Nudurupati S, Nigam A, Brooks JK, Bhatt DL, Michelson AD. A randomized, 2-period, crossover design study to assess the effects of dexlansoprazole, lansoprazole, esomeprazole, and omeprazole on the steady-state pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers. J Am Coll Cardiol. 2012 Apr 03; 59(14):1304-11. PMID: 22464259.
    Citations: 32     Fields:    Translation:HumansCells
  47. Jennings LK, Michelson AD, Jacoski MV, Tyagi A, Grgurevich S, Li JS. Pharmacodynamic effects of clopidogrel in pediatric cardiac patients: a comparative study of platelet aggregation response. Platelets. 2012; 23(6):430-8. PMID: 22309046.
    Citations:    Fields:    Translation:HumansCells
  48. Psaila B, Bussel JB, Linden MD, Babula B, Li Y, Barnard MR, Tate C, Mathur K, Frelinger AL, Michelson AD. In vivo effects of eltrombopag on platelet function in immune thrombocytopenia: no evidence of platelet activation. Blood. 2012 Apr 26; 119(17):4066-72. PMID: 22294727; PMCID: PMC3350368.
    Citations: 12     Fields:    Translation:HumansCells
  49. Mega JL, Hochholzer W, Frelinger AL, Kluk MJ, Angiolillo DJ, Kereiakes DJ, Isserman S, Rogers WJ, Ruff CT, Contant C, Pencina MJ, Scirica BM, Longtine JA, Michelson AD, Sabatine MS. Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease. JAMA. 2011 Nov 23; 306(20):2221-8. PMID: 22088980.
    Citations: 79     Fields:    Translation:Humans
  50. Psaila B, Bussel JB, Frelinger AL, Babula B, Linden MD, Li Y, Barnard MR, Tate C, Feldman EJ, Michelson AD. Differences in platelet function in patients with acute myeloid leukemia and myelodysplasia compared to equally thrombocytopenic patients with immune thrombocytopenia. J Thromb Haemost. 2011 Nov; 9(11):2302-10. PMID: 21920014; PMCID: PMC3210015.
    Citations: 11     Fields:    Translation:HumansCells
  51. Scheer FA, Michelson AD, Frelinger AL, Evoniuk H, Kelly EE, McCarthy M, Doamekpor LA, Barnard MR, Shea SA. The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors. PLoS One. 2011; 6(9):e24549. PMID: 21931750; PMCID: PMC3169622.
    Citations: 23     Fields:    Translation:Humans
  52. Frelinger AL, Michelson AD, Wiviott SD, Trenk D, Neumann FJ, Miller DL, Jakubowski JA, Costigan TM, McCabe CH, Antman EM, Braunwald E. Intrinsic platelet reactivity before P2Y12 blockade contributes to residual platelet reactivity despite high-level P2Y12 blockade by prasugrel or high-dose clopidogrel. Results from PRINCIPLE-TIMI 44. Thromb Haemost. 2011 Aug; 106(2):219-26. PMID: 21713327.
    Citations: 2     Fields:    Translation:Humans
  53. Ferrer-Marin F, Chavda C, Lampa M, Michelson AD, Frelinger AL, Sola-Visner M. Effects of in vitro adult platelet transfusions on neonatal hemostasis. J Thromb Haemost. 2011 May; 9(5):1020-8. PMID: 21320282; PMCID: PMC3130591.
    Citations: 7     Fields:    Translation:HumansCells
  54. Rahangdale S, Yeh SY, Novack V, Stevenson K, Barnard MR, Furman MI, Frelinger AL, Michelson AD, Malhotra A. The influence of intermittent hypoxemia on platelet activation in obese patients with obstructive sleep apnea. J Clin Sleep Med. 2011 Apr 15; 7(2):172-8. PMID: 21509332; PMCID: PMC3077345.
    Citations: 15     Fields:    Translation:Humans
  55. Angiolillo DJ, Badimon JJ, Saucedo JF, Frelinger AL, Michelson AD, Jakubowski JA, Zhu B, Ojeh CK, Baker BA, Effron MB. A pharmacodynamic comparison of prasugrel vs. high-dose clopidogrel in patients with type 2 diabetes mellitus and coronary artery disease: results of the Optimizing anti-Platelet Therapy In diabetes MellitUS (OPTIMUS)-3 Trial. Eur Heart J. 2011 Apr; 32(7):838-46. PMID: 21252171; PMCID: PMC3069388.
    Citations: 32     Fields:    Translation:Humans
  56. Trenor CC, Chung RJ, Michelson AD, Neufeld EJ, Gordon CM, Laufer MR, Emans SJ. Hormonal contraception and thrombotic risk: a multidisciplinary approach. Pediatrics. 2011 Feb; 127(2):347-57. PMID: 21199853; PMCID: PMC3025417.
    Citations: 12     Fields:    Translation:HumansAnimals
  57. Michelson AD. Advances in antiplatelet therapy. Hematology Am Soc Hematol Educ Program. 2011; 2011:62-9. PMID: 22160013.
    Citations: 13     Fields:    Translation:Humans
  58. Frelinger AL, Barnard MR, Fox ML, Michelson AD. The Platelet Activity After Clopidogrel Termination (PACT) study. Circ Cardiovasc Interv. 2010 Oct; 3(5):442-9. PMID: 20736449.
    Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
  59. Trenor CC, Michelson AD. Thrombophilia and pediatric stroke. Circulation. 2010 Apr 27; 121(16):1795-7. PMID: 20385934.
    Citations: 1     Fields:    Translation:Humans
  60. Michelson AD. Antiplatelet therapies for the treatment of cardiovascular disease. Nat Rev Drug Discov. 2010 Feb; 9(2):154-69. PMID: 20118963.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  61. Lajer M, Tarnow I, Michelson AD, Jorsal A, Frelinger AL, Parving HH, Rossing P, Tarnow L. Soluble CD40 ligand is elevated in type 1 diabetic nephropathy but not predictive of mortality, cardiovascular events or kidney function. Platelets. 2010; 21(7):525-32. PMID: 20701458.
    Citations: 7     Fields:    Translation:Humans
  62. Frelinger AL, Li Y, Linden MD, Barnard MR, Fox ML, Christie DJ, Furman MI, Michelson AD. Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. Circulation. 2009 Dec 22; 120(25):2586-96. PMID: 19996015.
    Citations: 30     Fields:    Translation:HumansCells
  63. Chang H, Yanachkov IB, Michelson AD, Li Y, Barnard MR, Wright GE, Frelinger AL. Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors. Thromb Res. 2010 Feb; 125(2):159-65. PMID: 19945153; PMCID: PMC2826549.
    Citations: 14     Fields:    Translation:HumansCells
  64. Przyklenk K, Frelinger AL, Linden MD, Whittaker P, Li Y, Barnard MR, Adams J, Morgan M, Al-Shamma H, Michelson AD. Targeted inhibition of the serotonin 5HT2A receptor improves coronary patency in an in vivo model of recurrent thrombosis. J Thromb Haemost. 2010 Feb; 8(2):331-40. PMID: 19922435; PMCID: PMC2916638.
    Citations: 19     Fields:    Translation:AnimalsCells
  65. Tarnow I, Michelson AD, Barnard MR, Frelinger AL, Aasted B, Jensen BR, Parving HH, Rossing P, Tarnow L. Nephropathy in type 1 diabetes is associated with increased circulating activated platelets and platelet hyperreactivity. Platelets. 2009 Nov; 20(7):513-9. PMID: 19852691.
    Citations: 3     Fields:    Translation:HumansCells
  66. Michelson AD. New P2Y12 antagonists. Curr Opin Hematol. 2009 Sep; 16(5):371-7. PMID: 19550317.
    Citations: 9     Fields:    Translation:Humans
  67. O'Donoghue ML, Braunwald E, Antman EM, Murphy SA, Bates ER, Rozenman Y, Michelson AD, Hautvast RW, Ver Lee PN, Close SL, Shen L, Mega JL, Sabatine MS, Wiviott SD. Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials. Lancet. 2009 Sep 19; 374(9694):989-997. PMID: 19726078.
    Citations: 120     Fields:    Translation:Humans
  68. Michelson AD, Frelinger AL, Braunwald E, Downey WE, Angiolillo DJ, Xenopoulos NP, Jakubowski JA, Li Y, Murphy SA, Qin J, McCabe CH, Antman EM, Wiviott SD. Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial. Eur Heart J. 2009 Jul; 30(14):1753-63. PMID: 19435740.
    Citations: 36     Fields:    Translation:HumansCells
  69. Cattaneo M, Hayward CP, Moffat KA, Pugliano MT, Liu Y, Michelson AD. Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of the SSC of the ISTH. J Thromb Haemost. 2009 Jun; 7(6):1029. PMID: 19422455.
    Citations: 22     Fields:    Translation:HumansCells
  70. Michelson AD. Methods for the measurement of platelet function. Am J Cardiol. 2009 Feb 02; 103(3 Suppl):20A-26A. PMID: 19166709.
    Citations: 47     Fields:    Translation:HumansCells
  71. Bednarek FJ, Bean S, Barnard MR, Frelinger AL, Michelson AD. The platelet hyporeactivity of extremely low birth weight neonates is age-dependent. Thromb Res. 2009 May; 124(1):42-5. PMID: 19026437.
    Citations: 4     Fields:    Translation:HumansCells
  72. Frelinger AL, Li Y, Linden MD, Tarnow I, Barnard MR, Fox ML, Michelson AD. Aspirin 'resistance': role of pre-existent platelet reactivity and correlation between tests. J Thromb Haemost. 2008 Dec; 6(12):2035-44. PMID: 18983514.
    Citations: 13     Fields:    Translation:Humans
  73. Trier DA, Gank KD, Kupferwasser D, Yount NY, French WJ, Michelson AD, Kupferwasser LI, Xiong YQ, Bayer AS, Yeaman MR. Platelet antistaphylococcal responses occur through P2X1 and P2Y12 receptor-induced activation and kinocidin release. Infect Immun. 2008 Dec; 76(12):5706-13. PMID: 18824536; PMCID: PMC2583569.
    Citations: 13     Fields:    Translation:AnimalsCells
  74. Darling CE, Michelson AD, Volturo GA, Przyklenk K. Platelet reactivity and the identification of acute coronary syndromes in the emergency department. J Thromb Thrombolysis. 2009 Jul; 28(1):31-7. PMID: 18600429.
    Citations: 2     Fields:    Translation:Humans
  75. Monagle P, Chalmers E, Chan A, deVeber G, Kirkham F, Massicotte P, Michelson AD. Antithrombotic therapy in neonates and children: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008 Jun; 133(6 Suppl):887S-968S. PMID: 18574281.
    Citations: 109     Fields:    Translation:Humans
  76. Tarnow I, Kristensen AT, Krogh AK, Frelinger AL, Barnard MR, Michelson AD. Effects of physiologic agonists on canine whole blood flow cytometry assays of leukocyte-platelet aggregation and platelet activation. Vet Immunol Immunopathol. 2008 Jun 15; 123(3-4):345-52. PMID: 18405981.
    Citations: 2     Fields:    Translation:AnimalsCells
  77. Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Antiplatelet therapy and platelet function testing. Introduction. Clin Cardiol. 2008 Mar; 31(3 Suppl 1):I1. PMID: 18481815.
    Citations:    Fields:    Translation:HumansCells
  78. Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Investigating the mechanisms of hyporesponse to antiplatelet approaches. Clin Cardiol. 2008 Mar; 31(3 Suppl 1):I21-7. PMID: 18481819.
    Citations:    Fields:    Translation:HumansCells
  79. Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Clinical considerations with the use of antiplatelet therapy in patients undergoing percutaneous coronary intervention. Clin Cardiol. 2008 Mar; 31(3 Suppl 1):I28-35. PMID: 18481820.
    Citations: 1     Fields:    Translation:HumansCells
  80. Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Antiplatelet therapy and platelet function testing. Clin Cardiol. 2008 Mar; 31(3 Suppl 1):I36. PMID: 18481821.
    Citations: 2     Fields:    Translation:HumansCells
  81. Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. The problem of persistent platelet activation in acute coronary syndromes and following percutaneous coronary intervention. Clin Cardiol. 2008 Mar; 31(3 Suppl 1):I17-20. PMID: 18481817.
    Citations: 4     Fields:    Translation:Humans
  82. Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Antiplatelet strategies: evaluating their current role in the setting of acute coronary syndromes. Clin Cardiol. 2008 Mar; 31(3 Suppl 1):I2-9. PMID: 18481818.
    Citations: 3     Fields:    Translation:HumansCells
  83. Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson AD, Peterson E, Wiviott S. Assessing the current role of platelet function testing. Clin Cardiol. 2008 Mar; 31(3 Suppl 1):I10-6. PMID: 18481816.
    Citations: 7     Fields:    Translation:HumansCells
  84. Li JS, Yow E, Berezny KY, Bokesch PM, Takahashi M, Graham TP, Sanders SP, Sidi D, Bonnet D, Ewert P, Jennings LK, Michelson AD. Dosing of clopidogrel for platelet inhibition in infants and young children: primary results of the Platelet Inhibition in Children On cLOpidogrel (PICOLO) trial. Circulation. 2008 Jan 29; 117(4):553-9. PMID: 18195173.
    Citations: 21     Fields:    Translation:Humans
  85. Michelson AD. P2Y12 antagonism: promises and challenges. Arterioscler Thromb Vasc Biol. 2008 Mar; 28(3):s33-8. PMID: 18174449.
    Citations: 19     Fields:    Translation:Humans
  86. Wiviott SD, Trenk D, Frelinger AL, O'Donoghue M, Neumann FJ, Michelson AD, Angiolillo DJ, Hod H, Montalescot G, Miller DL, Jakubowski JA, Cairns R, Murphy SA, McCabe CH, Antman EM, Braunwald E. Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial. Circulation. 2007 Dec 18; 116(25):2923-32. PMID: 18056526.
    Citations: 123     Fields:    Translation:HumansCTClinical Trials
  87. Frelinger AL, Jakubowski JA, Li Y, Barnard MR, Linden MD, Tarnow I, Fox ML, Sugidachi A, Winters KJ, Furman MI, Michelson AD. The active metabolite of prasugrel inhibits adenosine diphosphate- and collagen-stimulated platelet procoagulant activities. J Thromb Haemost. 2008 Feb; 6(2):359-65. PMID: 18021304.
    Citations: 7     Fields:    Translation:HumansCells
  88. Gurbel PA, Becker RC, Mann KG, Steinhubl SR, Michelson AD. Platelet function monitoring in patients with coronary artery disease. J Am Coll Cardiol. 2007 Nov 06; 50(19):1822-34. PMID: 17980247.
    Citations: 76     Fields:    Translation:Humans
  89. Linden MD, Barnard MR, Frelinger AL, Michelson AD, Przyklenk K. Effect of adenosine A2 receptor stimulation on platelet activation-aggregation: differences between canine and human models. Thromb Res. 2008; 121(5):689-98. PMID: 17727923; PMCID: PMC2346597.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  90. Frelinger AL, Jakubowski JA, Li Y, Barnard MR, Fox ML, Linden MD, Sugidachi A, Winters KJ, Furman MI, Michelson AD. The active metabolite of prasugrel inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: Influence of other blood cells, calcium, and aspirin. Thromb Haemost. 2007 Jul; 98(1):192-200. PMID: 17598013.
    Citations: 9     Fields:    Translation:HumansCells
  91. Tarnow I, Michelson AD, Frelinger AL, Linden MD, Li Y, Fox ML, Barnard MR, O'Sullivan BP. Cystic fibrosis heterozygotes do not have increased platelet activation. Thromb Res. 2007; 121(2):159-62. PMID: 17532368.
    Citations:    Fields:    Translation:Humans
  92. Linden MD, Furman MI, Frelinger AL, Fox ML, Barnard MR, Li Y, Przyklenk K, Michelson AD. Indices of platelet activation and the stability of coronary artery disease. J Thromb Haemost. 2007 Apr; 5(4):761-5. PMID: 17371489.
    Citations: 20     Fields:    Translation:HumansCells
  93. Harrison P, Frelinger AL, Furman MI, Michelson AD. Measuring antiplatelet drug effects in the laboratory. Thromb Res. 2007; 120(3):323-36. PMID: 17239428.
    Citations: 25     Fields:    Translation:HumansCells
  94. Michelson AD. Arterial ischemic stroke in children: baby steps. Circulation. 2006 Nov 14; 114(20):2094-5. PMID: 17101868.
    Citations:    Fields:    Translation:Humans
  95. Michelson AD, Frelinger AL, Furman MI. Current options in platelet function testing. Am J Cardiol. 2006 Nov 20; 98(10A):4N-10N. PMID: 17097417.
    Citations: 29     Fields:    Translation:Humans
  96. Michelson AD, Linden MD, Furman MI, Li Y, Barnard MR, Fox ML, Lau WC, McLaughlin TJ, Frelinger AL. Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance'. J Thromb Haemost. 2007 Jan; 5(1):75-81. PMID: 17002661.
    Citations: 11     Fields:    Translation:HumansCells
  97. Linden MD, Whittaker P, Frelinger AL, Barnard MR, Michelson AD, Przyklenk K. Preconditioning ischemia attenuates molecular indices of platelet activation-aggregation. J Thromb Haemost. 2006 Dec; 4(12):2670-7. PMID: 16995902.
    Citations: 8     Fields:    Translation:AnimalsCells
  98. Mirkhel A, Peyster E, Sundeen J, Greene L, Michelson AD, Hasan A, Domanski M. Frequency of aspirin resistance in a community hospital. Am J Cardiol. 2006 Sep 01; 98(5):577-9. PMID: 16923439.
    Citations: 10     Fields:    Translation:Humans
  99. Frelinger AL, Furman MI, Linden MD, Li Y, Fox ML, Barnard MR, Michelson AD. Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. Circulation. 2006 Jun 27; 113(25):2888-96. PMID: 16785341.
    Citations: 41     Fields:    Translation:HumansCells
  100. Michelson AD. Evaluation of platelet function by flow cytometry. Pathophysiol Haemost Thromb. 2006; 35(1-2):67-82. PMID: 16855350.
    Citations: 10     Fields:    Translation:Humans
  101. Kereiakes DJ, Michelson AD. Platelet activation and progression to complications. Rev Cardiovasc Med. 2006; 7(2):75-81. PMID: 16915126.
    Citations:    Fields:    Translation:HumansCells
  102. Wiviott SD, Michelson AD, Berger PB, Lepor NE, Kereiakes DJ. Therapeutic goals for effective platelet inhibition: a consensus document. Rev Cardiovasc Med. 2006; 7(4):214-25. PMID: 17224865.
    Citations: 1     Fields:    Translation:Humans
  103. Michelson AD. Aspirin resistance. Pathophysiol Haemost Thromb. 2006; 35(1-2):5-9. PMID: 16855339.
    Citations: 1     Fields:    Translation:HumansCells
  104. O'Sullivan BP, Michelson AD. The inflammatory role of platelets in cystic fibrosis. Am J Respir Crit Care Med. 2006 Mar 01; 173(5):483-90. PMID: 16339920.
    Citations: 14     Fields:    Translation:HumansCells
  105. Barnard MR, Linden MD, Frelinger AL, Li Y, Fox ML, Furman MI, Michelson AD. Effects of platelet binding on whole blood flow cytometry assays of monocyte and neutrophil procoagulant activity. J Thromb Haemost. 2005 Nov; 3(11):2563-70. PMID: 16241954.
    Citations: 12     Fields:    Translation:HumansCells
  106. Serebruany VL, Oshrine BR, Malinin AI, Atar D, Michelson AD, Ferguson JJ. Noncompliance in cardiovascular clinical trials. Am Heart J. 2005 Nov; 150(5):882-6. PMID: 16290953.
    Citations: 3     Fields:    Translation:Humans
  107. Frelinger AL, Michelson AD. Clopidogrel linking evaluation of platelet response variability to mechanism of action. J Am Coll Cardiol. 2005 Aug 16; 46(4):646-7. PMID: 16098429.
    Citations: 2     Fields:    Translation:HumansCells
  108. Eikelboom J, Feldman M, Mehta SR, Michelson AD, Oates JA, Topol E. Aspirin resistance and its implications in clinical practice. MedGenMed. 2005 Jul 11; 7(3):76. PMID: 16369302; PMCID: PMC1681651.
    Citations: 1     Fields:    Translation:HumansCells
  109. Michelson AD, Cattaneo M, Eikelboom JW, Gurbel P, Kottke-Marchant K, Kunicki TJ, Pulcinelli FM, Cerletti C, Rao AK. Aspirin resistance: position paper of the Working Group on Aspirin Resistance. J Thromb Haemost. 2005 Jun; 3(6):1309-11. PMID: 15892858.
    Citations: 39     Fields:    Translation:HumansCells
  110. O'Sullivan BP, Linden MD, Frelinger AL, Barnard MR, Spencer-Manzon M, Morris JE, Salem RO, Laposata M, Michelson AD. Platelet activation in cystic fibrosis. Blood. 2005 Jun 15; 105(12):4635-41. PMID: 15705796.
    Citations: 19     Fields:    Translation:HumansCells
  111. Furman MI, Krueger LA, Linden MD, Fox ML, Ball SP, Barnard MR, Frelinger AL, Michelson AD. GPIIb-IIIa antagonists reduce thromboinflammatory processes in patients with acute coronary syndromes undergoing percutaneous coronary intervention. J Thromb Haemost. 2005 Feb; 3(2):312-20. PMID: 15670038.
    Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
  112. Valeri CR, MacGregor H, Barnard MR, Summaria L, Michelson AD, Ragno G. Survival of baboon biotin-X-N-hydroxysuccinimide and (111)In-oxine-labelled autologous fresh and lyophilized reconstituted platelets. Vox Sang. 2005 Feb; 88(2):122-9. PMID: 15720610.
    Citations: 1     Fields:    Translation:AnimalsCells
  113. Israels SJ, Michelson AD. Antiplatelet therapy in children. Thromb Res. 2006; 118(1):75-83. PMID: 16709476.
    Citations: 7     Fields:    Translation:Humans
  114. Michelson AD. Platelet function testing in cardiovascular diseases. Hematology. 2005; 10 Suppl 1:132-7. PMID: 16188654.
    Citations: 1     Fields:    Translation:Humans
  115. Michelson AD. Platelet function testing in cardiovascular diseases. Circulation. 2004 Nov 09; 110(19):e489-93. PMID: 15533872.
    Citations: 47     Fields:    Translation:Humans
  116. Linden MD, Frelinger AL, Barnard MR, Przyklenk K, Furman MI, Michelson AD. Application of flow cytometry to platelet disorders. Semin Thromb Hemost. 2004 Oct; 30(5):501-11. PMID: 15497093.
    Citations: 15     Fields:    Translation:HumansCells
  117. Valeri CR, Macgregor H, Barnard MR, Summaria L, Michelson AD, Ragno G. In vitro testing of fresh and lyophilized reconstituted human and baboon platelets. Transfusion. 2004 Oct; 44(10):1505-12. PMID: 15383025.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  118. Monagle P, Chan A, Massicotte P, Chalmers E, Michelson AD. Antithrombotic therapy in children: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004 Sep; 126(3 Suppl):645S-687S. PMID: 15383489.
    Citations: 50     Fields:    Translation:HumansPHPublic Health
  119. Furman MI, Frelinger AL, Michelson AD. GPIIb/IIIa inhibitor-induced dethrombosis. J Thromb Thrombolysis. 2004 Aug; 18(1):11-7. PMID: 15744548.
    Citations: 4     Fields:    Translation:HumansAnimals
  120. Furman MI, Krueger LA, Linden MD, Barnard MR, Frelinger AL, Michelson AD. Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization. J Am Coll Cardiol. 2004 Jun 16; 43(12):2319-25. PMID: 15193700.
    Citations: 21     Fields:    Translation:HumansCells
  121. Frelinger AL, Furman MI, Barnard MR, Krueger LA, Dae MW, Michelson AD. Combined effects of mild hypothermia and glycoprotein IIb/IIIa antagonists on platelet-platelet and leukocyte-platelet aggregation. Am J Cardiol. 2003 Nov 01; 92(9):1099-101. PMID: 14583364.
    Citations: 7     Fields:    Translation:HumansCells
  122. Michelson AD. Platelet inhibitor therapy: mechanisms of action and clinical use. J Thromb Thrombolysis. 2003 Aug-Oct; 16(1-2):13-5. PMID: 14760206.
    Citations: 1     Fields:    Translation:HumansAnimals
  123. Michelson AD. How platelets work: platelet function and dysfunction. J Thromb Thrombolysis. 2003 Aug-Oct; 16(1-2):7-12. PMID: 14760205.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  124. Israels SJ, Rand ML, Michelson AD. Neonatal platelet function. Semin Thromb Hemost. 2003 Aug; 29(4):363-72. PMID: 14517748.
    Citations: 13     Fields:    Translation:HumansCells
  125. Alugupalli KR, Michelson AD, Joris I, Schwan TG, Hodivala-Dilke K, Hynes RO, Leong JM. Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis. Blood. 2003 Oct 15; 102(8):2843-50. PMID: 12855586.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  126. Barnard MR, Krueger LA, Frelinger AL, Furman MI, Michelson AD. Whole blood analysis of leukocyte-platelet aggregates. Curr Protoc Cytom. 2003 May; Chapter 6:Unit 6.15. PMID: 18770779.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  127. Chen J, Dong JF, Sun C, Bergeron A, McBride L, Pillai M, Barnard MR, Salmon J, Michelson AD, Bray PF. Platelet FcgammaRIIA His131Arg polymorphism and platelet function: antibodies to platelet-bound fibrinogen induce platelet activation. J Thromb Haemost. 2003 Feb; 1(2):355-62. PMID: 12871511.
    Citations: 3     Fields:    Translation:HumansCells
  128. Furman MI, Kereiakes DJ, Krueger LA, Mueller MN, Broderick TM, Schneider JF, Howard WL, Fox ML, Barnard MR, Frelinger AL, Michelson AD. Quantification of abciximab-induced platelet inhibition is assay dependent: a comparative study in patients undergoing percutaneous coronary intervention. Am Heart J. 2003 Feb; 145(2):e6. PMID: 12595861.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  129. Claytor RB, Michelson AD, Li JM, Frelinger AL, Rohrer MJ, Garnette CS, Barnard MR, Krueger LA, Furman MI. The cleaved peptide of PAR1 is a more potent stimulant of platelet-endothelial cell adhesion than is thrombin. J Vasc Surg. 2003 Feb; 37(2):440-5. PMID: 12563219.
    Citations: 1     Fields:    Translation:Humans
  130. Mitchell WB, Li JH, Singh F, Michelson AD, Bussel J, Coller BS, French DL. Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis. Blood. 2003 Mar 15; 101(6):2268-76. PMID: 12424194.
    Citations: 12     Fields:    Translation:HumansCells
  131. Rohrer MJ, Claytor RB, Garnette CS, Powell CC, Barnard MR, Furman MI, Michelson AD. Platelet-monocyte aggregates in patients with chronic venous insufficiency remain elevated following correction of reflux. Cardiovasc Surg. 2002 Oct; 10(5):464-9. PMID: 12379404.
    Citations: 1     Fields:    Translation:HumansCells
  132. Marciniak SJ, Mascelli MA, Furman MI, Michelson AD, Jakubowski JA, Jordan RE, Marchese PJ, Frelinger AL. An additional mechanism of action of abciximab: dispersal of newly formed platelet aggregates. Thromb Haemost. 2002 Jun; 87(6):1020-5. PMID: 12083481.
    Citations: 13     Fields:    Translation:HumansCells
  133. Wheeler GL, Braden GA, Steinhubl SR, Kereiakes DJ, Kottke-Marchant K, Michelson AD, Furman MI, Mueller MN, Moliterno DJ, Sane DC. The Ultegra rapid platelet-function assay: comparison to standard platelet function assays in patients undergoing percutaneous coronary intervention with abciximab therapy. Am Heart J. 2002 Apr; 143(4):602-11. PMID: 11923796.
    Citations: 5     Fields:    Translation:Humans
  134. Krueger LA, Barnard MR, Frelinger AL, Furman MI, Michelson AD. Immunophenotypic analysis of platelets. Curr Protoc Cytom. 2002 Feb; Chapter 6:Unit 6.10. PMID: 18770767.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  135. Furman MI, Kereiakes DJ, Krueger LA, Mueller MN, Pieper K, Broderick TM, Schneider JF, Howard WL, Fox ML, Barnard MR, Frelinger AL, Michelson AD. Leukocyte-platelet aggregation, platelet surface P-selectin, and platelet surface glycoprotein IIIa after percutaneous coronary intervention: Effects of dalteparin or unfractionated heparin in combination with abciximab. Am Heart J. 2001 Nov; 142(5):790-8. PMID: 11685164.
    Citations: 6     Fields:    Translation:HumansCells
  136. Furman MI, Barnard MR, Krueger LA, Fox ML, Shilale EA, Lessard DM, Marchese P, Frelinger AL, Goldberg RJ, Michelson AD. Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction. J Am Coll Cardiol. 2001 Oct; 38(4):1002-6. PMID: 11583872.
    Citations: 69     Fields:    Translation:HumansCells
  137. Michelson AD, Barnard MR, Krueger LA, Valeri CR, Furman MI. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation. 2001 Sep 25; 104(13):1533-7. PMID: 11571248.
    Citations: 111     Fields:    Translation:HumansAnimalsCells
  138. Frelinger AL, Furman MI, Krueger LA, Barnard MR, Michelson AD. Dissociation of glycoprotein IIb/IIIa antagonists from platelets does not result in fibrinogen binding or platelet aggregation. Circulation. 2001 Sep 18; 104(12):1374-9. PMID: 11560852.
    Citations: 7     Fields:    Translation:HumansCells
  139. Gardiner EE, De Luca M, McNally T, Michelson AD, Andrews RK, Berndt MC. Regulation of P-selectin binding to the neutrophil P-selectin counter-receptor P-selectin glycoprotein ligand-1 by neutrophil elastase and cathepsin G. Blood. 2001 Sep 01; 98(5):1440-7. PMID: 11520793.
    Citations: 9     Fields:    Translation:HumansCells
  140. Alugupalli KR, Michelson AD, Barnard MR, Leong JM. Serial determinations of platelet counts in mice by flow cytometry. Thromb Haemost. 2001 Aug; 86(2):668-71. PMID: 11522020.
    Citations: 12     Fields:    Translation:AnimalsCells
  141. Claytor RB, Li JM, Furman MI, Garnette CS, Rohrer MJ, Barnard MR, Krueger LA, Frelinger AL, Michelson AD. Laser scanning cytometry: a novel method for the detection of platelet--endothelial cell adhesion. Cytometry. 2001 Apr 01; 43(4):308-13. PMID: 11260598.
    Citations: 2     Fields:    Translation:HumansCells
  142. Monagle P, Michelson AD, Bovill E, Andrew M. Antithrombotic therapy in children. Chest. 2001 Jan; 119(1 Suppl):344S-370S. PMID: 11157659.
    Citations: 27     Fields:    Translation:Humans
  143. Alugupalli KR, Michelson AD, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM. Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. Mol Microbiol. 2001 Jan; 39(2):330-40. PMID: 11136454.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  144. Furman MI, Nurden P, Berndt MC, Nurden AT, Benoit SE, Barnard MR, Ofosu FA, Michelson AD. The cleaved peptide of PAR1 results in a redistribution of the platelet surface GPIb-IX-V complex to the surface-connected canalicular system. Thromb Haemost. 2000 Nov; 84(5):897-903. PMID: 11127874.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  145. Michelson AD, Rajasekhar D, Bednarek FJ, Barnard MR. Platelet and platelet-derived microparticle surface factor V/Va binding in whole blood: differences between neonates and adults. Thromb Haemost. 2000 Oct; 84(4):689-94. PMID: 11057871.
    Citations: 3     Fields:    Translation:HumansCells
  146. Furman MI, Frelinger III AL, Michelson AD. Antithrombotic therapy in the cardiac catheterization laboratory: focus on antiplatelet agents. Curr Cardiol Rep. 2000 Sep; 2(5):386-94. PMID: 10980905.
    Citations: 1     Fields:    Translation:Humans
  147. Furman MI, Krueger LA, Frelinger AL, Barnard MR, Mascelli MA, Nakada MT, Michelson AD. GPIIb-IIIa antagonist-induced reduction in platelet surface factor V/Va binding and phosphatidylserine expression in whole blood. Thromb Haemost. 2000 Sep; 84(3):492-8. PMID: 11019977.
    Citations: 9     Fields:    Translation:HumansCells
  148. Michelson AD, Barnard MR, Krueger LA, Frelinger AL, Furman MI. Evaluation of platelet function by flow cytometry. Methods. 2000 Jul; 21(3):259-70. PMID: 10873480.
    Citations: 24     Fields:    Translation:HumansCells
  149. Michelson AD, Furman MI, Goldschmidt-Clermont P, Mascelli MA, Hendrix C, Coleman L, Hamlington J, Barnard MR, Kickler T, Christie DJ, Kundu S, Bray PF. Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists. Circulation. 2000 Mar 07; 101(9):1013-8. PMID: 10704169.
    Citations: 42     Fields:    Translation:HumansCells
  150. Michelson AD. Flow cytometric analysis of platelets. Vox Sang. 2000; 78 Suppl 2:137-42. PMID: 10938943.
    Citations:    Fields:    Translation:HumansAnimalsCells
  151. Loscalzo J, Freedman J, Inbal A, Keaney JF, Michelson AD, Vita JA. Nitric oxide insufficiency and arterial thrombosis. Trans Am Clin Climatol Assoc. 2000; 111:158-63. PMID: 10881340; PMCID: PMC2194373.
    Citations:    Fields:    Translation:HumansCells
  152. Bussel JB, Kunicki TJ, Michelson AD. Platelets: New Understanding of Platelet Glycoproteins and Their Role in Disease. Hematology Am Soc Hematol Educ Program. 2000; 222-240. PMID: 11701544.
    Citations: 4     Fields:    
  153. Powell CC, Rohrer MJ, Barnard MR, Peyton BD, Furman MI, Michelson AD. Chronic venous insufficiency is associated with increased platelet and monocyte activation and aggregation. J Vasc Surg. 1999 Nov; 30(5):844-51. PMID: 10550182.
    Citations: 3     Fields:    Translation:HumansCells
  154. Michelson AD, Furman MI. Laboratory markers of platelet activation and their clinical significance. Curr Opin Hematol. 1999 Sep; 6(5):342-8. PMID: 10468151.
    Citations: 16     Fields:    Translation:Humans
  155. Barnard MR, MacGregor H, Ragno G, Pivacek LE, Khuri SF, Michelson AD, Valeri CR. Fresh, liquid-preserved, and cryopreserved platelets: adhesive surface receptors and membrane procoagulant activity. Transfusion. 1999 Aug; 39(8):880-8. PMID: 10504125.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  156. Kenet G, Freedman J, Shenkman B, Regina E, Brok-Simoni F, Holzman F, Vavva F, Brand N, Michelson A, Trolliet M, Loscalzo J, Inbal A. Plasma glutathione peroxidase deficiency and platelet insensitivity to nitric oxide in children with familial stroke. Arterioscler Thromb Vasc Biol. 1999 Aug; 19(8):2017-23. PMID: 10446087.
    Citations: 21     Fields:    Translation:HumansCells
  157. Barnard MR, MacGregor H, Mercier R, Ragno G, Pivacek LE, Hechtman HB, Michelson AD, Valeri CR. Platelet surface p-selectin, platelet-granulocyte heterotypic aggregates, and plasma-soluble p-selectin during plateletpheresis. Transfusion. 1999 Jul; 39(7):735-41. PMID: 10413281.
    Citations: 1     Fields:    Translation:HumansCells
  158. Pigazzi A, Heydrick S, Folli F, Benoit S, Michelson A, Loscalzo J. Nitric oxide inhibits thrombin receptor-activating peptide-induced phosphoinositide 3-kinase activity in human platelets. J Biol Chem. 1999 May 14; 274(20):14368-75. PMID: 10318860.
    Citations: 18     Fields:    Translation:HumansCells
  159. Michelson AD, Barnard MR, Khuri SF, Rohrer MJ, MacGregor H, Valeri CR. The effects of aspirin and hypothermia on platelet function in vivo. Br J Haematol. 1999 Jan; 104(1):64-8. PMID: 10027713.
    Citations: 3     Fields:    Translation:HumansCells
  160. Khuri SF, Healey N, MacGregor H, Barnard MR, Szymanski IO, Birjiniuk V, Michelson AD, Gagnon DR, Valeri CR. Comparison of the effects of transfusions of cryopreserved and liquid-preserved platelets on hemostasis and blood loss after cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1999 Jan; 117(1):172-83; discussion 183-4. PMID: 9869772.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  161. Michelson AD, Bovill E, Monagle P, Andrew M. Antithrombotic therapy in children. Chest. 1998 Nov; 114(5 Suppl):748S-769S. PMID: 9822076.
    Citations: 3     Fields:    Translation:Humans
  162. Himmelfarb J, Nelson S, McMonagle E, Holbrook D, Benoit SE, Michelson AD, Ault K. Elevated plasma glycocalicin levels and decreased ristocetin-induced platelet agglutination in hemodialysis patients. Am J Kidney Dis. 1998 Jul; 32(1):132-8. PMID: 9669434.
    Citations: 4     Fields:    Translation:HumansCells
  163. Peyton BD, Rohrer MJ, Furman MI, Barnard MR, Rodino LJ, Benoit SE, Hechtman HB, Valeri CR, Michelson AD. Patients with venous stasis ulceration have increased monocyte-platelet aggregation. J Vasc Surg. 1998 Jun; 27(6):1109-15; discussion 1115-6. PMID: 9652473.
    Citations: 1     Fields:    Translation:HumansCells
  164. Schmitz G, Rothe G, Ruf A, Barlage S, Tschöpe D, Clemetson KJ, Goodall AH, Michelson AD, Nurden AT, Shankey TV. European Working Group on Clinical Cell Analysis: Consensus protocol for the flow cytometric characterisation of platelet function. Thromb Haemost. 1998 May; 79(5):885-96. PMID: 9609215.
    Citations: 30     Fields:    Translation:HumansCells
  165. Andrew M, Michelson AD, Bovill E, Leaker M, Massicotte MP. Guidelines for antithrombotic therapy in pediatric patients. J Pediatr. 1998 Apr; 132(4):575-88. PMID: 9580753.
    Citations: 6     Fields:    Translation:Humans
  166. Furman MI, Liu L, Benoit SE, Becker RC, Barnard MR, Michelson AD. The cleaved peptide of the thrombin receptor is a strong platelet agonist. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):3082-7. PMID: 9501219; PMCID: PMC19698.
    Citations: 9     Fields:    Translation:HumansCells
  167. Furman MI, Benoit SE, Barnard MR, Valeri CR, Borbone ML, Becker RC, Hechtman HB, Michelson AD. Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J Am Coll Cardiol. 1998 Feb; 31(2):352-8. PMID: 9462579.
    Citations: 80     Fields:    Translation:HumansCells
  168. Michelson AD. Platelet function in the newborn. Semin Thromb Hemost. 1998; 24(6):507-12. PMID: 10066145.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  169. Freedman JE, Loscalzo J, Barnard MR, Alpert C, Keaney JF, Michelson AD. Nitric oxide released from activated platelets inhibits platelet recruitment. J Clin Invest. 1997 Jul 15; 100(2):350-6. PMID: 9218511; PMCID: PMC508197.
    Citations: 42     Fields:    Translation:HumansCells
  170. Rajasekhar D, Barnard MR, Bednarek FJ, Michelson AD. Platelet hyporeactivity in very low birth weight neonates. Thromb Haemost. 1997 May; 77(5):1002-7. PMID: 9184418.
    Citations: 7     Fields:    Translation:HumansCells
  171. Andrew M, Michelson AD, Bovill T, Leaker M, Massicotte P, Marzinotto V, Brooker LA. The prevention and treatment of thromboembolic disease in children: a need for Thrombophilia Programs. J Pediatr Hematol Oncol. 1997 Jan-Feb; 19(1):7-22. PMID: 9065714.
    Citations: 3     Fields:    Translation:Humans
  172. Michelson AD. Flow cytometric assessment of glycoprotein movements in platelets. Platelets. 1997; 8(2-3):105-15. PMID: 20297931.
    Citations:    Fields:    
  173. Michelson AD, Barnard MR, Hechtman HB, MacGregor H, Connolly RJ, Loscalzo J, Valeri CR. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11877-82. PMID: 8876231; PMCID: PMC38152.
    Citations: 65     Fields:    Translation:AnimalsCells
  174. Vander Salm TJ, Kaur S, Lancey RA, Okike ON, Pezzella AT, Stahl RF, Leone L, Li JM, Valeri CR, Michelson AD. Reduction of bleeding after heart operations through the prophylactic use of epsilon-aminocaproic acid. J Thorac Cardiovasc Surg. 1996 Oct; 112(4):1098-107. PMID: 8873738.
    Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
  175. Grabowski EF, Jang IK, Gold H, Head C, Benoit SE, Michelson AD. Variability of platelet degranulation by different contrast media. Acad Radiol. 1996 Sep; 3 Suppl 3:S485-7. PMID: 8883525.
    Citations: 5     Fields:    Translation:HumansCells
  176. Grabowski EF, Boor SE, Rodino LJ, Jang IK, Gold H, Michelson AD. Platelets are degranulated by some, but not all, contrast media. Acad Radiol. 1996 Aug; 3 Suppl 2:S328-30. PMID: 8796594.
    Citations:    Fields:    Translation:HumansCells
  177. Upchurch GR, Valeri CR, Khuri SF, Rohrer MJ, Welch GN, MacGregor H, Ragno G, Francis S, Rodino LJ, Michelson AD, Loscalzo J. Effect of heparin on fibrinolytic activity and platelet function in vivo. Am J Physiol. 1996 Aug; 271(2 Pt 2):H528-34. PMID: 8770093.
    Citations: 2     Fields:    Translation:AnimalsCells
  178. Michelson AD. Flow cytometry: a clinical test of platelet function. Blood. 1996 Jun 15; 87(12):4925-36. PMID: 8652804.
    Citations: 42     Fields:    Translation:HumansCells
  179. Michelson AD, Benoit SE, Furman MI, Breckwoldt WL, Rohrer MJ, Barnard MR, Loscalzo J. Effects of nitric oxide/EDRF on platelet surface glycoproteins. Am J Physiol. 1996 May; 270(5 Pt 2):H1640-8. PMID: 8928869.
    Citations: 18     Fields:    Translation:Humans
  180. Li JM, Podolsky RS, Rohrer MJ, Cutler BS, Massie MT, Barnard MR, Michelson AD. Adhesion of activated platelets to venous endothelial cells is mediated via GPIIb/IIIa. J Surg Res. 1996 Mar; 61(2):543-8. PMID: 8656640.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  181. Michelson AD, Benoit SE, Furman MI, Barnard MR, Nurden P, Nurden AT. The platelet surface expression of glycoprotein V is regulated by two independent mechanisms: proteolysis and a reversible cytoskeletal-mediated redistribution to the surface-connected canalicular system. Blood. 1996 Feb 15; 87(4):1396-408. PMID: 8608229.
    Citations: 2     Fields:    Translation:HumansCells
  182. Freedman JE, Loscalzo J, Benoit SE, Valeri CR, Barnard MR, Michelson AD. Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis. J Clin Invest. 1996 Feb 15; 97(4):979-87. PMID: 8613552; PMCID: PMC507144.
    Citations: 29     Fields:    Translation:Humans
  183. Barnard MR, Michelson AD. Images in clinical medicine. A morphologic question. N Engl J Med. 1995 Oct 19; 333(16):1051. PMID: 7675048.
    Citations:    Fields:    Translation:AnimalsCells
  184. Michelson AD, Bovill E, Andrew M. Antithrombotic therapy in children. Chest. 1995 Oct; 108(4 Suppl):506S-522S. PMID: 7555200.
    Citations: 13     Fields:    Translation:Humans
  185. Kamat SG, Michelson AD, Benoit SE, Moake JL, Rajasekhar D, Hellums JD, Kroll MH, Schafer AI. Fibrinolysis inhibits shear stress-induced platelet aggregation. Circulation. 1995 Sep 15; 92(6):1399-407. PMID: 7664419.
    Citations: 6     Fields:    Translation:Humans
  186. Grabowski EF, Jang IK, Gold H, Palacios IF, Boor SE, Rodino LJ, Michelson AD. Platelet degranulation induced by some contrast media is independent of their nonionic vs ionic nature. Acta Radiol Suppl. 1995; 399:182-4. PMID: 8610512.
    Citations:    Fields: