Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Sushrut Subhash Waikar, M.D.

Title
Institution
Department
Address
Phone
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Profile Picture

Biography
awards and honors
1992
James Olds Memorial Neuroscience Award
1993
Sigma Xi Research Honors Society
2001
Mentor of the Year Award (by internal medicine housestaff)
2007
Excellence in tutorial facilitation -- Introduction to Human Physiology
2011
Physician of the Year, Renal Division
2015 - 2019
Constantine L. Hampers, MD Distinguished Chair in Renal Medicine
2019
Norman G. Levinsky Professor of Medicine

Overview

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
  1. U01DK130060 (BHALLA, VIVEK) Aug 25, 2021 - Jun 30, 2026
    NIH
    Discovery Science Collaborative for CKDu
    Role: Co-Principal Investigator
  2. R25DK128858 (WAIKAR, SUSHRUT S.) Apr 1, 2021 - Feb 28, 2026
    NIH
    The Boston University Kidney and Medical Engineering Program (BU-KIDMEP)
    Role: Principal Investigator
  3. R21DK119751 (WAIKAR, SUSHRUT S.) Sep 15, 2019 - Jan 31, 2021
    NIH
    Metabolomics and Renal Functional Reserve
    Role: Principal Investigator
  4. UH3DK114915 (WAIKAR, SUSHRUT S.) Sep 18, 2017 - Jun 30, 2022
    NIH
    Harvard Chronic Kidney Disease Research Biopsy Center
    Role: Principal Investigator
  5. UG3DK114915 (WAIKAR, SUSHRUT S.) Sep 18, 2017 - Jun 30, 2019
    NIH
    Harvard Chronic Kidney Disease Research Biopsy Center
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Johnson MJ, Tommerdahl KL, Vinovskis C, Waikar S, Reinicke T, Parikh CR, Obeid W, Nelson RG, van Raalte DH, Pyle L, Nadeau KJ, Bjornstad P. Relationship between biomarkers of tubular injury and intrarenal hemodynamic dysfunction in youth with type 1 diabetes. Pediatr Nephrol. 2022 Mar 14. PMID: 35286453.
    Citations:    Fields:    
  2. Singh AT, Waikar SS, Mc Causland FR. Association of Different Definitions of Intradialytic Hypertension With Long-Term Mortality in Hemodialysis. Hypertension. 2022 Apr; 79(4):855-862. PMID: 35166122.
    Citations:    Fields:    
  3. Rhee EP, Surapaneni A, Zheng Z, Zhou L, Dutta D, Arking DE, Zhang J, Duong T, Chatterjee N, Luo S, Schlosser P, Mehta R, Waikar SS, Saraf SL, Kelly TN, Hamm LL, Rao PS, Mathew AV, Hsu CY, Parsa A, Vasan RS, Kimmel PL, Clish CB, Coresh J, Feldman HI, Grams ME. Trans-ethnic genome-wide association study of blood metabolites in the Chronic Renal Insufficiency Cohort (CRIC) study. Kidney Int. 2022 Apr; 101(4):814-823. PMID: 35120996.
    Citations:    Fields:    
  4. Liu J, Tio MC, Verma A, Schmidt IM, Ilori TO, Knauf F, Mc Causland FR, Waikar SS. Determinants and Outcomes Associated With Urinary Calcium Excretion in Chronic Kidney Disease. J Clin Endocrinol Metab. 2022 01 01; 107(1):e281-e292. PMID: 34390334.
    Citations:    Fields:    Translation:Humans
  5. Koopman JJE, Rennke HG, McMahon GM, Waikar SS, Costenbader KH. Associations between renal deposits of complement factors, disease activity and loss of renal function in lupus nephritis. J Clin Pathol. 2021 Dec 30. PMID: 34969783.
    Citations:    Fields:    
  6. Kilgallon JL, Gannon M, Burns Z, McMahon G, Dykes P, Linder J, Bates DW, Waikar S, Lipsitz S, Baer HJ, Samal L. Multicomponent intervention to improve blood pressure management in chronic kidney disease: a protocol for a pragmatic clinical trial. BMJ Open. 2021 12 22; 11(12):e054065. PMID: 34937722.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  7. Kelly YP, Mistry K, Ahmed S, Shaykevich S, Desai S, Lipsitz SR, Leaf DE, Mandel EI, Robinson E, McMahon G, Czarnecki PG, Charytan DM, Waikar SS, Mendu ML. Controlled Study of Decision-Making Algorithms for Kidney Replacement Therapy Initiation in Acute Kidney Injury. Clin J Am Soc Nephrol. 2022 02; 17(2):194-204. PMID: 34911731.
    Citations:    Fields:    
  8. Butler CR, Appelbaum PS, Ascani H, Aulisio M, Campbell CE, de Boer IH, Dighe AL, Hall DE, Himmelfarb J, Knight R, Mehl K, Murugan R, Rosas SE, Sedor JR, O'Toole JF, Tuttle KR, Waikar SS, Freeman M. A Participant-Centered Approach to Understanding Risks and Benefits of Participation in Research Informed by the Kidney Precision Medicine Project. Am J Kidney Dis. 2021 Dec 04. PMID: 34871700.
    Citations:    Fields:    
  9. Perkovic V, Blackorby A, Cizman B, Carroll K, Cobitz AR, Davies R, DiMino TL, Jha V, Johansen KL, Lopes RD, Kler L, Macdougall IC, McMurray JJV, Meadowcroft AM, Obrador GT, Solomon S, Taft L, Wanner C, Waikar SS, Wheeler DC, Wiecek A, Singh AK. The ASCEND-ND trial: Study design and participant characteristics. Nephrol Dial Transplant. 2021 Dec 02. PMID: 34865143.
    Citations: 1     Fields:    
  10. Causland FRM, Ravi KS, Curtis KA, Kibbelaar ZA, Short SAP, Singh AT, Correa S, Waikar SS. A randomized controlled trial of two dialysate sodium concentrations in hospitalized hemodialysis patients. Nephrol Dial Transplant. 2021 Nov 18. PMID: 34792161.
    Citations:    Fields:    
  11. Jain A, Huang R, Lee J, Jawa N, Lim YJ, Guron M, Abish S, Boutros PC, Brudno M, Carleton B, Cuvelier GDE, Gunaratnam L, Ho C, Adeli K, Kuruvilla S, Lajoie G, Liu G, Nathan PC, Rod Rassekh S, Rieder M, Waikar SS, Welch SA, Weir MA, Winquist E, Wishart DS, Zorzi AP, Blydt-Hansen T, Zappitelli M, Urquhart B. A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol. Can J Kidney Health Dis. 2021; 8:20543581211057708. PMID: 34820133.
    Citations:    
  12. Schmidt IM, Sarvode Mothi S, Wilson PC, Palsson R, Srivastava A, Onul IF, Kibbelaar ZA, Zhuo M, Amodu A, Stillman IE, Rennke HG, Humphreys BD, Waikar SS. Circulating Plasma Biomarkers in Biopsy-Confirmed Kidney Disease. Clin J Am Soc Nephrol. 2022 01; 17(1):27-37. PMID: 34759008.
    Citations:    Fields:    
  13. Gutiérrez OM, Shlipak MG, Katz R, Waikar SS, Greenberg JH, Schrauben SJ, Coca S, Parikh CR, Vasan RS, Feldman HI, Kimmel PL, Cushman M, Bonventre JV, Sarnak MJ, Ix JH. Associations of Plasma Biomarkers of Inflammation, Fibrosis, and Kidney Tubular Injury With Progression of Diabetic Kidney Disease: A Cohort Study. Am J Kidney Dis. 2021 Nov 06. PMID: 34752914.
    Citations: 2     Fields:    
  14. Singh AK, Carroll K, Perkovic V, Solomon S, Jha V, Johansen KL, Lopes RD, Macdougall IC, Obrador GT, Waikar SS, Wanner C, Wheeler DC, Wiecek A, Blackorby A, Cizman B, Cobitz AR, Davies R, Dole J, Kler L, Meadowcroft AM, Zhu X, McMurray JJV. Daprodustat for the Treatment of Anemia in Patients Undergoing Dialysis. N Engl J Med. 2021 12 16; 385(25):2325-2335. PMID: 34739194.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  15. Singh AK, Carroll K, McMurray JJV, Solomon S, Jha V, Johansen KL, Lopes RD, Macdougall IC, Obrador GT, Waikar SS, Wanner C, Wheeler DC, Wiecek A, Blackorby A, Cizman B, Cobitz AR, Davies R, DiMino TL, Kler L, Meadowcroft AM, Taft L, Perkovic V. Daprodustat for the Treatment of Anemia in Patients Not Undergoing Dialysis. N Engl J Med. 2021 12 16; 385(25):2313-2324. PMID: 34739196.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  16. Watts AJB, Keller KH, Lerner G, Rosales I, Collins AB, Sekulic M, Waikar SS, Chandraker A, Riella LV, Alexander MP, Troost JP, Chen J, Fermin D, Yee JL, Sampson MG, Beck LH, Henderson JM, Greka A, Rennke HG, Weins A. Discovery of Autoantibodies Targeting Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology. J Am Soc Nephrol. 2022 01; 33(1):238-252. PMID: 34732507.
    Citations: 3     Fields:    Translation:HumansCells
  17. Correa S, Guerra-Torres XE, Waikar SS, Mc Causland FR. Serum Magnesium, Blood Pressure, and Risk of Hypertension and Chronic Kidney Disease Progression in the CRIC Study. Hypertension. 2021 12; 78(6):1771-1780. PMID: 34757763.
    Citations: 1     Fields:    Translation:Humans
  18. Raundhal M, Ghosh S, Myers SA, Cuoco MS, Singer M, Carr SA, Waikar SS, Bonventre JV, Ritz J, Stone RM, Steensma DP, Regev A, Glimcher LH. Author Correction: Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias. Nat Immunol. 2021 Nov; 22(11):1465. PMID: 34522041.
    Citations:    Fields:    
  19. Garimella PS, Katz R, Waikar SS, Srivastava A, Schmidt I, Hoofnagle A, Palsson R, Rennke HG, Stillman IE, Wang K, Kestenbaum BR, Ix JH. Kidney Tubulointerstitial Fibrosis and Tubular Secretion. Am J Kidney Dis. 2021 Sep 24. PMID: 34571064.
    Citations:    Fields:    
  20. Hsu CY, Yang W, Parikh RV, Anderson AH, Chen TK, Cohen DL, He J, Mohanty MJ, Lash JP, Mills KT, Muiru AN, Parsa A, Saunders MR, Shafi T, Townsend RR, Waikar SS, Wang J, Wolf M, Tan TC, Feldman HI, Go AS. Race, Genetic Ancestry, and Estimating Kidney Function in CKD. N Engl J Med. 2021 11 04; 385(19):1750-1760. PMID: 34554660.
    Citations: 7     Fields:    Translation:Humans
  21. Amodu A, Porteny T, Schmidt IM, Ladin K, Waikar SS. Nephrologists' Attitudes Toward Native Kidney Biopsy: A Qualitative Study. Kidney Med. 2021 Nov-Dec; 3(6):1022-1031. PMID: 34939011.
    Citations: 1     
  22. Greenberg JH, Abraham AG, Xu Y, Schelling JR, Feldman HI, Sabbisetti VS, Ix JH, Jogalekar MP, Coca S, Waikar SS, Shlipak MG, Warady BA, Vasan RS, Kimmel PL, Bonventre JV, Denburg M, Parikh CR, Furth S. Urine Biomarkers of Kidney Tubule Health, Injury, and Inflammation are Associated with Progression of CKD in Children. J Am Soc Nephrol. 2021 10; 32(10):2664-2677. PMID: 34544821.
    Citations:    Fields:    Translation:Humans
  23. Schwarzschild MA, Ascherio A, Casaceli C, Curhan GC, Fitzgerald R, Kamp C, Lungu C, Macklin EA, Marek K, Mozaffarian D, Oakes D, Rudolph A, Shoulson I, Videnovic A, Scott B, Gauger L, Aldred J, Bixby M, Ciccarello J, Gunzler SA, Henchcliffe C, Brodsky M, Keith K, Hauser RA, Goetz C, LeDoux MS, Hinson V, Kumar R, Espay AJ, Jimenez-Shahed J, Hunter C, Christine C, Daley A, Leehey M, de Marcaida JA, Friedman JH, Hung A, Bwala G, Litvan I, Simon DK, Simuni T, Poon C, Schiess MC, Chou K, Park A, Bhatti D, Peterson C, Criswell SR, Rosenthal L, Durphy J, Shill HA, Mehta SH, Ahmed A, Deik AF, Fang JY, Stover N, Zhang L, Dewey RB, Gerald A, Boyd JT, Houston E, Suski V, Mosovsky S, Cloud L, Shah BB, Saint-Hilaire M, James R, Zauber SE, Reich S, Shprecher D, Pahwa R, Langhammer A, LaFaver K, LeWitt PA, Kaminski P, Goudreau J, Russell D, Houghton DJ, Laroche A, Thomas K, McGraw M, Mari Z, Serrano C, Blindauer K, Rabin M, Kurlan R, Morgan JC, Soileau M, Ainslie M, Bodis-Wollner I, Schneider RB, Waters C, Ratel AS, Beck CA, Bolger P, Callahan KF, Crotty GF, Klements D, Kostrzebski M, McMahon GM, Pothier L, Waikar SS, Lang A, Mestre T. Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial. JAMA. 2021 09 14; 326(10):926-939. PMID: 34519802.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  24. Correa S, Guerra-Torres XE, Ravi KS, Mothi SS, Waikar SS, Mc Causland FR. Risk of Intradialytic Hypotension by Day of the Week in Maintenance Hemodialysis. ASAIO J. 2021 Sep 07. PMID: 34494985.
    Citations:    Fields:    
  25. Adler JT, Xiang L, Weissman JS, Rodrigue JR, Patzer RE, Waikar SS, Tsai TC. Association of Public Reporting of Medicare Dialysis Facility Quality Ratings With Access to Kidney Transplantation. JAMA Netw Open. 2021 09 01; 4(9):e2126719. PMID: 34559227.
    Citations:    Fields:    Translation:Humans
  26. Pfau A, Ermer T, Coca SG, Tio MC, Genser B, Reichel M, Finkelstein FO, März W, Wanner C, Waikar SS, Eckardt KU, Aronson PS, Drechsler C, Knauf F. High Oxalate Concentrations Correlate with Increased Risk for Sudden Cardiac Death in Dialysis Patients. J Am Soc Nephrol. 2021 09; 32(9):2375-2385. PMID: 34281958.
    Citations:    Fields:    Translation:Humans
  27. Kelly YP, Sharma S, Mothi SS, McCausland FR, Mendu ML, McMahon GM, Palevsky PM, Waikar SS. Hypocalcemia is associated with hypotension during CRRT: A secondary analysis of the Acute Renal Failure Trial Network Study. J Crit Care. 2021 10; 65:261-267. PMID: 34274834.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  28. Ravi KS, Reeves PB, Correa S, Neves JS, Waikar SS, Mothi SS, Mc Causland FR. Predialysis serum phosphate and intradialytic hypotension. Hemodial Int. 2022 01; 26(1):38-47. PMID: 34236130.
    Citations:    Fields:    
  29. Singh AT, Mothi SS, Li P, Sabbisetti V, Waikar SS, Mc Causland FR. Endothelin-1 and Parameters of Systolic Blood Pressure in Hemodialysis. Am J Hypertens. 2021 Jun 30. PMID: 34192305.
    Citations: 1     Fields:    
  30. Verma A, Chitalia VC, Waikar SS, Kolachalama VB. Machine Learning Applications in Nephrology: A Bibliometric Analysis Comparing Kidney Studies to Other Medicine Subspecialities. Kidney Med. 2021 Sep-Oct; 3(5):762-767. PMID: 34693256.
    Citations:    
  31. Schmidt IM, Srivastava A, Sabbisetti V, McMahon GM, He J, Chen J, Kusek JW, Taliercio J, Ricardo AC, Hsu CY, Kimmel PL, Liu KD, Mifflin TE, Nelson RG, Vasan RS, Xie D, Zhang X, Palsson R, Stillman IE, Rennke HG, Feldman HI, Bonventre JV, Waikar SS. Plasma Kidney Injury Molecule 1 in CKD: Findings From the Boston Kidney Biopsy Cohort and CRIC Studies. Am J Kidney Dis. 2022 02; 79(2):231-243.e1. PMID: 34175376.
    Citations: 4     Fields:    Translation:Humans
  32. Gannon MP, Wu E, McMahon GM, Aaron S, Bates DW, Waikar S, Samal L. Uncontrolled blood pressure and treatment of hypertension in older chronic kidney disease patients. J Am Geriatr Soc. 2021 10; 69(10):2985-2987. PMID: 34089261.
    Citations:    Fields:    Translation:Humans
  33. Kamel MH, Mahmoud H, Zhen A, Liu J, Bielick CG, Mostaghim A, Lin N, Chitalia V, Ilori T, Waikar SS, Upadhyay A. End-stage kidney disease and COVID-19 in an urban safety-net hospital in Boston, Massachusetts. PLoS One. 2021; 16(6):e0252679. PMID: 34086775.
    Citations: 1     Fields:    Translation:HumansCells
  34. Schmidt IM, Colona MR, Kestenbaum BR, Alexopoulos LG, Palsson R, Srivastava A, Liu J, Stillman IE, Rennke HG, Vaidya VS, Wu H, Humphreys BD, Waikar SS. Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis. Kidney Int. 2021 09; 100(3):672-683. PMID: 34051265.
    Citations:    Fields:    Translation:Humans
  35. Zheng Y, Cassol CA, Jung S, Veerapaneni D, Chitalia VC, Ren KYM, Bellur SS, Boor P, Barisoni LM, Waikar SS, Betke M, Kolachalama VB. Deep-Learning-Driven Quantification of Interstitial Fibrosis in Digitized Kidney Biopsies. Am J Pathol. 2021 08; 191(8):1442-1453. PMID: 34033750.
    Citations: 1     Fields:    Translation:Humans
  36. Scovner KM, Correa S, Claggett BL, Barrett CD, Waikar SS, Solomon SD, Mc Causland FR. Specific Electrocardiograph Intervals Predict Hospitalization with Atrial Fibrillation in Those with Chronic Kidney Disease. Am J Nephrol. 2021; 52(5):412-419. PMID: 33951623.
    Citations:    Fields:    Translation:Humans
  37. Wettersten N, Katz R, Shlipak MG, Scherzer R, Waikar SS, Ix JH, Estrella MM. Urinary Biomarkers and Kidney Outcomes: Impact of Indexing Versus Adjusting for Urinary Creatinine. Kidney Med. 2021 Jul-Aug; 3(4):546-554.e1. PMID: 34401722.
    Citations:    
  38. Correa S, Curtis KA, Waikar SS, Mc Causland FR. Serum Myeloperoxidase, Uric Acid, and the Risk of Atrial Fibrillation in Chronic Kidney Disease. Circ Arrhythm Electrophysiol. 2021 04; 14(4):e009483. PMID: 33858180.
    Citations:    Fields:    Translation:Humans
  39. Muto Y, Wilson PC, Ledru N, Wu H, Dimke H, Waikar SS, Humphreys BD. Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney. Nat Commun. 2021 04 13; 12(1):2190. PMID: 33850129.
    Citations: 24     Fields:    Translation:HumansCells
  40. Srivastava A, Cai X, Mehta R, Lee J, Chu DI, Mills KT, Shafi T, Taliercio JJ, Hsu JY, Schrauben SJ, Saunders MR, Diamantidis CJ, Hsu CY, Waikar SS, Lash JP, Isakova T. Hospitalization Trajectories and Risks of ESKD and Death in Individuals With CKD. Kidney Int Rep. 2021 Jun; 6(6):1592-1602. PMID: 34169199.
    Citations: 1     
  41. Raundhal M, Ghosh S, Myers SA, Cuoco MS, Singer M, Carr SA, Waikar SS, Bonventre JV, Ritz J, Stone RM, Steensma DP, Regev A, Glimcher LH. Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias. Nat Immunol. 2021 04; 22(4):520-529. PMID: 33753942.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  42. Singh AK, Blackorby A, Cizman B, Carroll K, Cobitz AR, Davies R, Jha V, Johansen KL, Lopes RD, Kler L, Macdougall IC, McMurray J, Meadowcroft AM, Obrador GT, Perkovic V, Solomon S, Wanner C, Waikar SS, Wheeler DC, Wiecek A. Study design and baseline characteristics of patients on dialysis in the ASCEND-D trial. Nephrol Dial Transplant. 2021 Mar 21. PMID: 33744933.
    Citations: 1     Fields:    
  43. de Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, He Y, Hodgin JB, Jain S, Kellum JA, Kiryluk K, Knight R, Laszik ZG, Lienczewski C, Mariani LH, McClelland RL, Menez S, Moledina DG, Mooney SD, O'Toole JF, Palevsky PM, Parikh CR, Poggio ED, Rosas SE, Rosengart MR, Sarwal MM, Schaub JA, Sedor JR, Sharma K, Steck B, Toto RD, Troyanskaya OG, Tuttle KR, Vazquez MA, Waikar SS, Williams K, Wilson FP, Zhang K, Iyengar R, Kretzler M, Himmelfarb J. Rationale and design of the Kidney Precision Medicine Project. Kidney Int. 2021 03; 99(3):498-510. PMID: 33637194.
    Citations: 9     Fields:    Translation:Humans
  44. Schmidt IM, Waikar SS. Separate and Unequal: Race-Based Algorithms and Implications for Nephrology. J Am Soc Nephrol. 2021 03; 32(3):529-533. PMID: 33510038.
    Citations: 3     Fields:    Translation:Humans
  45. Jadhav S, Tripathi S, Chandrekar A, Waikar SS, Hsiao LL. A novel antibody for the detection of alternatively spliced secreted KLOTHO isoform in human plasma. PLoS One. 2021; 16(1):e0245614. PMID: 33481901.
    Citations: 1     Fields:    Translation:HumansCells
  46. Zheng Z, Waikar SS, Schmidt IM, Landis JR, Hsu CY, Shafi T, Feldman HI, Anderson AH, Wilson FP, Chen J, Rincon-Choles H, Ricardo AC, Saab G, Isakova T, Kallem R, Fink JC, Rao PS, Xie D, Yang W. Subtyping CKD Patients by Consensus Clustering: The Chronic Renal Insufficiency Cohort (CRIC) Study. J Am Soc Nephrol. 2021 03; 32(3):639-653. PMID: 33462081.
    Citations: 6     Fields:    Translation:Humans
  47. Chen Y, Zelnick LR, Huber MP, Wang K, Bansal N, Hoofnagle AN, Paranji RK, Heckbert SR, Weiss NS, Go AS, Hsu CY, Feldman HI, Waikar SS, Mehta RC, Srivastava A, Seliger SL, Lash JP, Porter AC, Raj DS, Kestenbaum BR. Association Between Kidney Clearance of Secretory Solutes and Cardiovascular Events: The Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2021 08; 78(2):226-235.e1. PMID: 33421453.
    Citations: 1     Fields:    Translation:Humans
  48. Srivastava A, Schmidt IM, Palsson R, Weins A, Bonventre JV, Sabbisetti V, Stillman IE, Rennke HG, Waikar SS. The Associations of Plasma Biomarkers of Inflammation With Histopathologic Lesions, Kidney Disease Progression, and Mortality-The Boston Kidney Biopsy Cohort Study. Kidney Int Rep. 2021 Mar; 6(3):685-694. PMID: 33732983.
    Citations: 4     
  49. Feldman CH, Speyer C, Ashby R, L Bermas B, Bhattacharyya S, Chakravarty E, Everett B, Ferucci E, Hersh AO, Marty FM, Merola JF, Ramsey-Goldman R, Rovin BH, Son MB, Tarter L, Waikar S, Yazdany J, Weissman JS, Costenbader KH. Development of a Set of Lupus-Specific, Ambulatory Care-Sensitive, Potentially Preventable Adverse Conditions: A Delphi Consensus Study. Arthritis Care Res (Hoboken). 2021 01; 73(1):146-157. PMID: 31628721.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  50. Koopman JJE, Rennke HG, Leatherwood C, Speyer CB, D'Silva K, McMahon GM, Waikar SS, Costenbader KH. Renal deposits of complement factors as predictors of end-stage renal disease and death in patients with lupus nephritis. Rheumatology (Oxford). 2020 12 01; 59(12):3751-3758. PMID: 32413140.
    Citations: 1     Fields:    Translation:Humans
  51. Chen Y, Zelnick LR, Wang K, Katz R, Hoofnagle AN, Becker JO, Hsu CY, Go AS, Feldman HI, Mehta RC, Lash JP, Waikar SS, Hamm L, Chen J, Shafi T, Kestenbaum BR. Association of tubular solute clearances with the glomerular filtration rate and complications of chronic kidney disease: the Chronic Renal Insufficiency Cohort study. Nephrol Dial Transplant. 2020 Nov 17. PMID: 33330914.
    Citations:    Fields:    
  52. Hannan M, Ansari S, Meza N, Anderson AH, Srivastava A, Waikar S, Charleston J, Weir MR, Taliercio J, Horwitz E, Saunders MR, Wolfrum K, Feldman HI, Lash JP, Ricardo AC. Risk Factors for CKD Progression: Overview of Findings from the CRIC Study. Clin J Am Soc Nephrol. 2021 04 07; 16(4):648-659. PMID: 33177074.
    Citations: 10     Fields:    Translation:Humans
  53. Schrauben SJ, Shou H, Zhang X, Anderson AH, Bonventre JV, Chen J, Coca S, Furth SL, Greenberg JH, Gutierrez OM, Ix JH, Lash JP, Parikh CR, Rebholz CM, Sabbisetti V, Sarnak MJ, Shlipak MG, Waikar SS, Kimmel PL, Vasan RS, Feldman HI, Schelling JR. Association of Multiple Plasma Biomarker Concentrations with Progression of Prevalent Diabetic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study. J Am Soc Nephrol. 2021 01; 32(1):115-126. PMID: 33122288.
    Citations: 13     Fields:    Translation:Humans
  54. Li P, Gupta S, Mothi SS, Rennke HG, Leaf DE, Waikar SS, McMahon GM. Histopathologic Correlates of Kidney Function: Insights From Nephrectomy Specimens. Am J Kidney Dis. 2021 03; 77(3):336-345. PMID: 33098926.
    Citations: 3     Fields:    Translation:Humans
  55. Verma A, Patel AB, Tio MC, Waikar SS. Caring for Dialysis Patients in a Time of COVID-19. Kidney Med. 2020 Oct 14. PMID: 33073227.
    Citations: 5     
  56. Gupta S, Tio MC, Gutowski ED, Stecker MS, Verma A, Motwani SS, Mount DB, McMahon GM, Waikar SS. Incidence of Hyponatremia in Patients With Indwelling Peritoneal Catheters for Drainage of Malignant Ascites. JAMA Netw Open. 2020 10 01; 3(10):e2017859. PMID: 33104204.
    Citations: 1     Fields:    Translation:Humans
  57. Nuzzo PV, Berchuck JE, Korthauer K, Spisak S, Nassar AH, Alaiwi SA, Chakravarthy A, Shen SY, Bakouny Z, Boccardo F, Steinharter J, Bouchard G, Curran CR, Pan W, Baca SC, Seo JH, Lee GM, Michaelson MD, Chang SL, Waikar SS, Sonpavde G, Irizarry RA, Pomerantz M, De Carvalho DD, Choueiri TK, Freedman ML. Author Correction: Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nat Med. 2020 Oct; 26(10):1663. PMID: 32895574.
    Citations: 3     Fields:    
  58. Liu CK, Ghai S, Waikar SS, Weiner DE. COVID-19 Infection Risk Among Hemodialysis Patients in Long-term Care Facilities. Kidney Med. 2020 Nov-Dec; 2(6):810-811. PMID: 33015605.
    Citations: 5     
  59. Ong E, Wang LL, Schaub J, O'Toole JF, Steck B, Rosenberg AZ, Dowd F, Hansen J, Barisoni L, Jain S, de Boer IH, Valerius MT, Waikar SS, Park C, Crawford DC, Alexandrov T, Anderton CR, Stoeckert C, Weng C, Diehl AD, Mungall CJ, Haendel M, Robinson PN, Himmelfarb J, Iyengar R, Kretzler M, Mooney S, He Y. Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project. Nat Rev Nephrol. 2020 11; 16(11):686-696. PMID: 32939051.
    Citations: 9     Fields:    Translation:Humans
  60. Koopman JJE, Scherzer R, Ix JH, Shlipak MG, Waikar SS. A Comparison of Different Estimates of Albuminuria in Association with Mortality in Epidemiologic Research. Clin J Am Soc Nephrol. 2020 12 07; 15(12):1814-1816. PMID: 32928745.
    Citations: 1     Fields:    Translation:Humans
  61. Bargagli M, Tio MC, Waikar SS, Ferraro PM. Dietary Oxalate Intake and Kidney Outcomes. Nutrients. 2020 Sep 02; 12(9). PMID: 32887293.
    Citations: 6     Fields:    Translation:HumansAnimals
  62. Burns RB, Waikar SS, Wachterman MW, Kanjee Z. Management Options for an Older Adult With Advanced Chronic Kidney Disease and Dementia: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Ann Intern Med. 2020 08 04; 173(3):217-225. PMID: 32745449.
    Citations:    Fields:    Translation:Humans
  63. Palsson R, Colona MR, Hoenig MP, Lundquist AL, Novak JE, Perazella MA, Waikar SS. Assessment of Interobserver Reliability of Nephrologist Examination of Urine Sediment. JAMA Netw Open. 2020 08 03; 3(8):e2013959. PMID: 32821922.
    Citations: 2     Fields:    Translation:Humans
  64. Verma A, Patel AB, Waikar SS. SGLT2 Inhibitor: Not a Traditional Diuretic for Heart Failure. Cell Metab. 2020 07 07; 32(1):13-14. PMID: 32640243.
    Citations: 2     Fields:    Translation:Humans
  65. Schmidt IM, Verma A, Waikar SS. Circulating plasma angiotensin-converting enzyme 2 concentrations in patients with kidney disease. Eur Heart J. 2020 07 01; 41(32):3097-3098. PMID: 32691065.
    Citations: 3     Fields:    Translation:Humans
  66. Ayus JC, Fuentes N, Go AS, Achinger SG, Moritz ML, Nigwekar SU, Waikar SS, Negri AL. Chronicity of Uncorrected Hyponatremia and Clinical Outcomes in Older Patients Undergoing Hip Fracture Repair. Front Med (Lausanne). 2020; 7:263. PMID: 32695787.
    Citations: 1     
  67. Nuzzo PV, Berchuck JE, Korthauer K, Spisak S, Nassar AH, Abou Alaiwi S, Chakravarthy A, Shen SY, Bakouny Z, Boccardo F, Steinharter J, Bouchard G, Curran CR, Pan W, Baca SC, Seo JH, Lee GM, Michaelson MD, Chang SL, Waikar SS, Sonpavde G, Irizarry RA, Pomerantz M, De Carvalho DD, Choueiri TK, Freedman ML. Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nat Med. 2020 07; 26(7):1041-1043. PMID: 32572266.
    Citations: 40     Fields:    Translation:HumansCells
  68. Sise ME, Strohbehn I, Chute D, Corey KE, Fusco DN, Sabbisetti VS, Waikar SS, Chung RT. Low Complement C4 Predicts Improvement of Kidney Function After Direct-Acting Antiviral Therapy for Hepatitis C Virus. Hepatol Commun. 2020 Aug; 4(8):1206-1217. PMID: 32766479.
    Citations: 1     Fields:    
  69. Stern LD, Waikar S. Time to Expand Access and Utilization of Home Dialysis: Lessons From the COVID-19 Pandemic. Mayo Clin Proc. 2020 07; 95(7):1323-1324. PMID: 32622441.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  70. Hod T, Freedberg KJ, Motwani SS, Chen M, Frendl G, Leaf DE, Gupta S, Mothi SS, Richards WG, Bueno R, Waikar SS. Acute kidney injury after cytoreductive surgery and hyperthermic intraoperative cisplatin chemotherapy for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2021 Apr; 161(4):1510-1518. PMID: 32631662.
    Citations: 3     Fields:    Translation:Humans
  71. Sharma S, Kelly YP, Palevsky PM, Waikar SS. Intensity of Renal Replacement Therapy and Duration of Mechanical Ventilation: Secondary Analysis of the Acute Renal Failure Trial Network Study. Chest. 2020 10; 158(4):1473-1481. PMID: 32470389.
    Citations: 5     Fields:    Translation:Humans
  72. Li P, Schmidt IM, Sabbisetti V, Tio MC, Opotowsky AR, Waikar SS. Plasma Endothelin-1 and Risk of Death and Hospitalization in Patients Undergoing Maintenance Hemodialysis. Clin J Am Soc Nephrol. 2020 06 08; 15(6):784-793. PMID: 32381583.
    Citations: 2     Fields:    Translation:Humans
  73. Kwan B, Fuhrer T, Zhang J, Darshi M, Van Espen B, Montemayor D, de Boer IH, Dobre M, Hsu CY, Kelly TN, Raj DS, Rao PS, Saraf SL, Scialla J, Waikar SS, Sharma K, Natarajan L. Metabolomic Markers of Kidney Function Decline in Patients With Diabetes: Evidence From the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2020 10; 76(4):511-520. PMID: 32387023.
    Citations: 11     Fields:    Translation:Humans
  74. Palsson R, Chandraker AK, Curhan GC, Rennke HG, McMahon GM, Waikar SS. The association of calcium oxalate deposition in kidney allografts with graft and patient survival. Nephrol Dial Transplant. 2020 05 01; 35(5):888-894. PMID: 30165691.
    Citations: 11     Fields:    Translation:Humans
  75. Hudson JI, Kanayama G, Pope HG, Muse S, Kaufman MJ, Baggish A, Waikar SS. Glomerular Filtration Rate and Supraphysiologic-Dose Anabolic-Androgenic Steroid Use: A Cross-sectional Cohort Study. Am J Kidney Dis. 2020 07; 76(1):152-155. PMID: 32362416.
    Citations: 1     Fields:    Translation:Humans
  76. Verma A, Patel AB, Upadhyay A, Waikar SS. CREDENCE: Significant Victory for Diabetic Kidney Disease. Trends Endocrinol Metab. 2020 06; 31(6):391-393. PMID: 32327275.
    Citations:    Fields:    Translation:Humans
  77. Neves JS, Correa S, Baeta Baptista R, Bigotte Vieira M, Waikar SS, Mc Causland FR. Association of Prediabetes With CKD Progression and Adverse Cardiovascular Outcomes: An Analysis of the CRIC Study. J Clin Endocrinol Metab. 2020 04 01; 105(4). PMID: 31943096.
    Citations: 3     Fields:    Translation:Humans
  78. Greenberg JH, Abraham AG, Xu Y, Schelling JR, Feldman HI, Sabbisetti VS, Gonzalez MC, Coca S, Schrauben SJ, Waikar SS, Ramachandran VS, Shlipak MG, Warady B, Kimmel PL, Bonventre JV, Denburg M, Parikh CR, Furth S. Plasma Biomarkers of Tubular Injury and Inflammation Are Associated with CKD Progression in Children. J Am Soc Nephrol. 2020 05; 31(5):1067-1077. PMID: 32234829.
    Citations: 21     Fields:    Translation:Humans
  79. Chen Y, Zelnick LR, Wang K, Hoofnagle AN, Becker JO, Hsu CY, Feldman HI, Mehta RC, Lash JP, Waikar SS, Shafi T, Seliger SL, Shlipak MG, Rahman M, Kestenbaum BR. Kidney Clearance of Secretory Solutes Is Associated with Progression of CKD: The CRIC Study. J Am Soc Nephrol. 2020 04; 31(4):817-827. PMID: 32205410.
    Citations: 12     Fields:    Translation:Humans
  80. Palsson R, Short SAP, Kibbelaar ZA, Amodu A, Stillman IE, Rennke HG, McMahon GM, Waikar SS. Bleeding Complications After Percutaneous Native Kidney Biopsy: Results From the Boston Kidney Biopsy Cohort. Kidney Int Rep. 2020 Apr; 5(4):511-518. PMID: 32274455.
    Citations: 10     
  81. Simic P, Kim W, Zhou W, Pierce KA, Chang W, Sykes DB, Aziz NB, Elmariah S, Ngo D, Pajevic PD, Govea N, Kestenbaum BR, de Boer IH, Cheng Z, Christov M, Chun J, Leaf DE, Waikar SS, Tager AM, Gerszten RE, Thadhani RI, Clish CB, Jüppner H, Wein MN, Rhee EP. Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney. J Clin Invest. 2020 03 02; 130(3):1513-1526. PMID: 32065590.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  82. Hayek SS, Leaf DE, Samman Tahhan A, Raad M, Sharma S, Waikar SS, Sever S, Camacho A, Wang X, Dande RR, Ibrahim NE, Baron RM, Altintas MM, Wei C, Sheikh-Hamad D, Pan JS, Holliday MW, Januzzi JL, Weisbord SD, Quyyumi AA, Reiser J. Soluble Urokinase Receptor and Acute Kidney Injury. N Engl J Med. 2020 01 30; 382(5):416-426. PMID: 31995687.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  83. Gupta S, McMahon GM, Motwani SS, Mount DB, Waikar SS. "Pleurex Desalination" in Malignancy-related Ascites: A Novel Mechanism of Hyponatremia. Am J Clin Oncol. 2020 01; 43(1):14-19. PMID: 31592807.
    Citations: 1     Fields:    Translation:Humans
  84. Correa S, Pena-Esparragoza JK, Scovner KM, Waikar SS, Mc Causland FR. Myeloperoxidase and the Risk of CKD Progression, Cardiovascular Disease, and Death in the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2020 07; 76(1):32-41. PMID: 31864821.
    Citations: 7     Fields:    Translation:Humans
  85. McMahon GM, Amodu A, Sise ME, Mothi SS, Palsson R, Waikar SS. Physician Attitudes on Kidney Biopsies for Research: A Survey Study. Kidney Med. 2020 Jan-Feb; 2(1):82-84. PMID: 32734230.
    Citations:    
  86. Ku E, Yang W, McCulloch CE, Feldman HI, Go AS, Lash J, Bansal N, He J, Horwitz E, Ricardo AC, Shafi T, Sondheimer J, Townsend RR, Waikar SS, Hsu CY. Race and Mortality in CKD and Dialysis: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2020 03; 75(3):394-403. PMID: 31732235.
    Citations: 4     Fields:    Translation:Humans
  87. Kefaloyianni E, Keerthi Raja MR, Schumacher J, Muthu ML, Krishnadoss V, Waikar SS, Herrlich A. Proximal Tubule-Derived Amphiregulin Amplifies and Integrates Profibrotic EGF Receptor Signals in Kidney Fibrosis. J Am Soc Nephrol. 2019 12; 30(12):2370-2383. PMID: 31676723.
    Citations: 10     Fields:    Translation:AnimalsCells
  88. Wachterman MW, Leveille T, Keating NL, Simon SR, Waikar SS, Bokhour B. Nephrologists' emotional burden regarding decision-making about dialysis initiation in older adults: a qualitative study. BMC Nephrol. 2019 10 24; 20(1):385. PMID: 31651262.
    Citations: 2     Fields:    Translation:Humans
  89. Wilson PC, Wu H, Kirita Y, Uchimura K, Ledru N, Rennke HG, Welling PA, Waikar SS, Humphreys BD. The single-cell transcriptomic landscape of early human diabetic nephropathy. Proc Natl Acad Sci U S A. 2019 09 24; 116(39):19619-19625. PMID: 31506348.
    Citations: 89     Fields:    Translation:HumansCells
  90. Leaf DE, Waikar SS. IDEAL-ICU in Context. Clin J Am Soc Nephrol. 2019 08 07; 14(8):1264-1267. PMID: 31315886.
    Citations: 2     Fields:    Translation:Humans
  91. Efe O, Verma A, Waikar SS. Urinary oxalate as a potential mediator of kidney disease in diabetes mellitus and obesity. Curr Opin Nephrol Hypertens. 2019 07; 28(4):316-320. PMID: 31045662.
    Citations: 5     Fields:    Translation:Humans
  92. Leatherwood C, Speyer CB, Feldman CH, D'Silva K, Gómez-Puerta JA, Hoover PJ, Waikar SS, McMahon GM, Rennke HG, Costenbader KH. Clinical characteristics and renal prognosis associated with interstitial fibrosis and tubular atrophy (IFTA) and vascular injury in lupus nephritis biopsies. Semin Arthritis Rheum. 2019 12; 49(3):396-404. PMID: 31277928.
    Citations: 9     Fields:    Translation:Humans
  93. Opotowsky AR, Carazo M, Singh MN, Dimopoulos K, Cardona-Estrada DA, Elantably A, Waikar SS, Mc Causland FR, Veldtman G, Grewal J, Gray C, Loukas BN, Rajpal S. Creatinine versus cystatin C to estimate glomerular filtration rate in adults with congenital heart disease: Results of the Boston Adult Congenital Heart Disease Biobank. Am Heart J. 2019 08; 214:142-155. PMID: 31203159.
    Citations: 1     Fields:    Translation:Humans
  94. Sekulic M, Waikar S, Motwani SS, Weins A, Rennke HG. Chromogranin A Tubulopathy: Differing Histopathologic Patterns of Acute Tubular Injury in the Setting of Neuroendocrine Neoplasms. Kidney Int Rep. 2019 Aug; 4(8):1085-1093. PMID: 31440699.
    Citations: 1     
  95. Sharma S, Christov M, Ix JH, Waikar SS. Clearance of FGF-23 during continuous renal replacement therapy. Hemodial Int. 2019 07; 23(3):366-368. PMID: 31037817.
    Citations: 1     Fields:    Translation:Humans
  96. Mc Causland FR, Claggett B, Sabbisetti VS, Jarolim P, Waikar SS. Hypertonic Mannitol for the Prevention of Intradialytic Hypotension: A Randomized Controlled Trial. Am J Kidney Dis. 2019 10; 74(4):483-490. PMID: 31040088.
    Citations: 2     Fields:    Translation:Humans
  97. Waikar SS. Precision nosology versus precision nephrology: defining acute kidney injury, again. Kidney Int. 2019 04; 95(4):741-743. PMID: 30904062.
    Citations: 1     Fields:    Translation:Humans
  98. Waikar SS, Srivastava A, Palsson R, Shafi T, Hsu CY, Sharma K, Lash JP, Chen J, He J, Lieske J, Xie D, Zhang X, Feldman HI, Curhan GC. Association of Urinary Oxalate Excretion With the Risk of Chronic Kidney Disease Progression. JAMA Intern Med. 2019 04 01; 179(4):542-551. PMID: 30830167.
    Citations: 21     Fields:    Translation:Humans
  99. Naik GS, Waikar SS, Johnson AEW, Buchbinder EI, Haq R, Hodi FS, Schoenfeld JD, Ott PA. Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition. J Immunother Cancer. 2019 03 29; 7(1):89. PMID: 30922394.
    Citations: 37     Fields:    Translation:Humans
  100. Mendu ML, Ahmed S, Maron JK, Rao SK, Chaguturu SK, May MF, Mutter WP, Burdge KA, Steele DJR, Mount DB, Waikar SS, Weilburg JB, Sequist TD. Development of an electronic health record-based chronic kidney disease registry to promote population health management. BMC Nephrol. 2019 03 01; 20(1):72. PMID: 30823871.
    Citations: 4     Fields:    Translation:Humans
  101. Palsson R, Srivastava A, Waikar SS. Performance of the Automated Urinalysis in Diagnosis of Proliferative Glomerulonephritis. Kidney Int Rep. 2019 May; 4(5):723-727. PMID: 31080928.
    Citations: 1     
  102. Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Boerger EAS, Mc Causland FR, Eisenga MF, Singh K, Babitt JL, Kellum JA, Palevsky PM, Christov M, Waikar SS. Iron, Hepcidin, and Death in Human AKI. J Am Soc Nephrol. 2019 03; 30(3):493-504. PMID: 30737269.
    Citations: 12     Fields:    Translation:Humans
  103. Luo S, Coresh J, Tin A, Rebholz CM, Appel LJ, Chen J, Vasan RS, Anderson AH, Feldman HI, Kimmel PL, Waikar SS, Köttgen A, Evans AM, Levey AS, Inker LA, Sarnak MJ, Grams ME. Serum Metabolomic Alterations Associated with Proteinuria in CKD. Clin J Am Soc Nephrol. 2019 03 07; 14(3):342-353. PMID: 30733224.
    Citations: 18     Fields:    Translation:Humans
  104. Kelly YP, Waikar SS, Mendu ML. When to stop renal replacement therapy in anticipation of renal recovery in AKI: The need for consensus guidelines. Semin Dial. 2019 05; 32(3):205-209. PMID: 30690779.
    Citations: 2     Fields:    Translation:Humans
  105. Srivastava A, Palsson R, Leaf DE, Higuera A, Chen ME, Palacios P, Baron RM, Sabbisetti V, Hoofnagle AN, Vaingankar SM, Palevsky PM, Waikar SS. Uric Acid and Acute Kidney Injury in the Critically Ill. Kidney Med. 2019 Jan-Feb; 1(1):21-30. PMID: 32734180.
    Citations: 2     
  106. Coresh J, Heerspink HJL, Sang Y, Matsushita K, Arnlov J, Astor BC, Black C, Brunskill NJ, Carrero JJ, Feldman HI, Fox CS, Inker LA, Ishani A, Ito S, Jassal S, Konta T, Polkinghorne K, Romundstad S, Solbu MD, Stempniewicz N, Stengel B, Tonelli M, Umesawa M, Waikar SS, Wen CP, Wetzels JFM, Woodward M, Grams ME, Kovesdy CP, Levey AS, Gansevoort RT. Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies. Lancet Diabetes Endocrinol. 2019 02; 7(2):115-127. PMID: 30635225.