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Kelan Tantisira, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL129935 (TANTISIRA, KELAN G) Sep 15, 2015 - Jun 30, 2018
    NIH/NHLBI
    DISEASE AND HEALTH: ASTHMA RESILIENCE THROUGH MICRORNA ATTRIBUTES (DHARMA)
    Role: Principal Investigator
  2. R01HL127332 (TANTISIRA, KELAN G) Sep 1, 2015 - Jun 30, 2019
    NIH/NHLBI
    MICRORNAS IN CIRCULATION: ONTOLOGIES OF ASTHMA SEVERITY AND TREATMENT (MICROCOAST)
    Role: Principal Investigator
  3. R01NR013391 (TANTISIRA, KELAN G) Sep 27, 2011 - Jul 31, 2014
    NIH/NINR
    GENOMICS AND PHARMACOGENOMICS OF SYMPTOMS IN ASTHMA
    Role: Principal Investigator
  4. R21HL107927 (DEMEO, DAWN L) Apr 1, 2011 - Jan 31, 2014
    NIH/NHLBI
    CIGARETTE SMOKE IMPACTS FETAL LUNG DNA METHYLATION AND GENE EXPRESSION
    Role: Co-Principal Investigator
  5. R01HL092197 (TANTISIRA, KELAN G) May 1, 2009 - Mar 31, 2014
    NIH/NHLBI
    INTEGRATIVE PHARMACOGENOMICS OF LEUKOTRIENE INHIBITION IN ASTHMA
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wang AL, Qiu W, DeMeo DL, Raby BA, Weiss ST, Tantisira KG. DNA methylation is associated with improvement in lung function on inhaled corticosteroids in pediatric asthmatics. Pharmacogenet Genomics. 2019 Jan 11. PMID: 30640894.
    Citations:    Fields:    
  2. Sordillo JE, McGeachie M, Lutz SM, Lasky-Su J, Tantisira K, Tsai CH, Dahlin A, Kelly R, Wu AC. Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype. Pediatr Pulmonol. 2019 Feb; 54(2):158-164. PMID: 30585438.
    Citations:    Fields:    
  3. Dahlin A, Sordillo JE, Ziniti J, Iribarren C, Lu M, Weiss ST, Tantisira KG, Lu Q, Kan M, Himes BE, Jorgenson E, Wu AC. Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults. J Allergy Clin Immunol. 2018 Dec 20. PMID: 30578877.
    Citations:    Fields:    
  4. Barrios J, Kho AT, Aven L, Mitchel JA, Park JA, Randell SH, Miller LA, Tantisira KG, Ai X. Pulmonary Neuroendocrine Cells Secrete GABA to Induce Goblet Cell Hyperplasia in Primate Models. Am J Respir Cell Mol Biol. 2018 Dec 20. PMID: 30571139.
    Citations:    Fields:    
  5. Park HW, Dahlin A, Qiu W, Tantisira KG. Gene expression changes in lymphoblastoid cell lines and primary B cells by dexamethasone. Pharmacogenet Genomics. 2018 Dec 15. PMID: 30562215.
    Citations:    Fields:    
  6. Wang AL, Datta S, Weiss ST, Tantisira KG. Remission of persistent childhood asthma: Early predictors of adult outcomes. J Allergy Clin Immunol. 2018 Nov 14. PMID: 30445065.
    Citations:    
  7. Choi J, Tantisira KG, Duan QL. Whole genome sequencing identifies high-impact variants in well-known pharmacogenomic genes. Pharmacogenomics J. 2018 Sep 14. PMID: 30214008.
    Citations:    Fields:    
  8. Cho M, Tantisira K. ¡HOLA! The Influence of Being Hispanic on Lung Ancestry. Am J Respir Crit Care Med. 2018 Jul 15; 198(2):148-149. PMID: 29533681.
    Citations:    Fields:    
  9. Li X, Fu Y, Wang X, DeMeo DL, Tantisira K, Weiss ST, Qiu W. Detecting Differentially Variable MicroRNAs via Model-Based Clustering. Int J Genomics. 2018; 2018:6591634. PMID: 30116730.
    Citations:    
  10. Farzan N, Vijverberg SJ, Hernandez-Pacheco N, Bel EHD, Berce V, Bønnelykke K, Bisgaard H, Burchard EG, Canino G, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Forno E, Francis B, Hawcutt DB, Herrera-Luis E, Kabesch M, Karimi L, Melén E, Mukhopadhyay S, Merid SK, Palmer CN, Pino-Yanes M, Pirmohamed M, Potocnik U, Repnik K, Schieck M, Sevelsted A, Sio YY, Smyth RL, Soares P, Söderhäll C, Tantisira KG, Tavendale R, Tse SM, Turner S, Verhamme KM, Maitland-van der Zee AH. 17q21 variant increases the risk of exacerbations in asthmatic children despite inhaled corticosteroids use. Allergy. 2018 Oct; 73(10):2083-2088. PMID: 29885281.
    Citations:    Fields:    
  11. Park HW, Song WJ, Cho SH, McGeachie MJ, Martinez F, Mauger D, Bender BG, Tantisira KG. Assessment of genetic factor and depression interactions for asthma symptom severity in cohorts of childhood and elderly asthmatics. Exp Mol Med. 2018 07 04; 50(7):77. PMID: 29973587.
    Citations:    Fields:    
  12. Kho AT, McGeachie MJ, Moore KG, Sylvia JM, Weiss ST, Tantisira KG. Circulating microRNAs and prediction of asthma exacerbation in childhood asthma. Respir Res. 2018 06 26; 19(1):128. PMID: 29940952.
    Citations:    Fields:    Translation:Humans
  13. Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton TJ, Nguyen TA, Torgerson DG, Kwok PY, Levin AM, Celedón JC, Forno E, Hakonarson H, Sleiman PM, Dahlin A, Tantisira KG, Weiss ST, Serebrisky D, Brigino-Buenaventura E, Farber HJ, Meade K, Lenoir MA, Avila PC, Sen S, Thyne SM, Rodriguez-Cintron W, Winkler CA, Moreno-Estrada A, Sandoval K, Rodriguez-Santana JR, Kumar R, Williams LK, Ahituv N, Ziv E, Seibold MA, Darnell RB, Zaitlen N, Hernandez RD, Burchard EG. Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. Am J Respir Crit Care Med. 2018 Jun 15; 197(12):1552-1564. PMID: 29509491.
    Citations:    Fields:    
  14. Cho MH, Tantisira KG. Adrenal insufficiency and ICS: genetics takes a breath. Lancet Respir Med. 2018 06; 6(6):407-408. PMID: 29551625.
    Citations:    Fields:    Translation:Humans
  15. McGeachie MJ, Clemmer GL, Hayete B, Xing H, Runge K, Wu AC, Jiang X, Lu Q, Church B, Khalil I, Tantisira K, Weiss S. Systems biology and in vitro validation identifies family with sequence similarity 129 member A (FAM129A) as an asthma steroid response modulator. J Allergy Clin Immunol. 2018 Nov; 142(5):1479-1488.e12. PMID: 29410046.
    Citations:    Fields:    
  16. Panganiban RA, Sun M, Dahlin A, Park HR, Kan M, Himes BE, Mitchel JA, Iribarren C, Jorgenson E, Randell SH, Israel E, Tantisira K, Shore S, Park JA, Weiss ST, Wu AC, Lu Q. A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis. J Allergy Clin Immunol. 2018 Nov; 142(5):1469-1478.e2. PMID: 29330013.
    Citations: 1     Fields:    
  17. Dahlin A, Qiu W, Litonjua AA, Lima JJ, Tamari M, Kubo M, Irvin CG, Peters SP, Wu AC, Weiss ST, Tantisira KG. The phosphatidylinositide 3-kinase (PI3K) signaling pathway is a determinant of zileuton response in adults with asthma. Pharmacogenomics J. 2018 09; 18(5):665-677. PMID: 29298996.
    Citations: 1     Fields:    
  18. Mirzakhani H, De Vivo I, Leeder JS, Gaedigk R, Vyhlidal CA, Weiss ST, Tantisira K. Early pregnancy intrauterine fetal exposure to maternal smoking and impact on fetal telomere length. Eur J Obstet Gynecol Reprod Biol. 2017 Nov; 218:27-32. PMID: 28926727.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  19. Jiang X, Dahlin A, Weiss ST, Tantisira K, Lu Q. A high-throughput chemical screen identifies novel inhibitors and enhancers of anti-inflammatory functions of the glucocorticoid receptor. Sci Rep. 2017 08 07; 7(1):7405. PMID: 28785063.
    Citations:    Fields:    
  20. Davis JS, Sun M, Kho AT, Moore KG, Sylvia JM, Weiss ST, Lu Q, Tantisira KG. Circulating microRNAs and association with methacholine PC20 in the Childhood Asthma Management Program (CAMP) cohort. PLoS One. 2017; 12(7):e0180329. PMID: 28749975.
    Citations: 1     Fields:    Translation:HumansCells
  21. Qiu W, Guo F, Glass K, Yuan GC, Quackenbush J, Zhou X, Tantisira KG. Differential connectivity of gene regulatory networks distinguishes corticosteroid response in asthma. J Allergy Clin Immunol. 2018 Apr; 141(4):1250-1258. PMID: 28736268.
    Citations:    Fields:    
  22. Farzan N, Vijverberg SJ, Andiappan AK, Arianto L, Berce V, Blanca-López N, Bisgaard H, Bønnelykke K, Burchard EG, Campo P, Canino G, Carleton B, Celedón JC, Chew FT, Chiang WC, Cloutier MM, Daley D, Den Dekker HT, Dijk FN, Duijts L, Flores C, Forno E, Hawcutt DB, Hernandez-Pacheco N, de Jongste JC, Kabesch M, Koppelman GH, Manolopoulos VG, Melén E, Mukhopadhyay S, Nilsson S, Palmer CN, Pino-Yanes M, Pirmohamed M, Potocnik U, Raaijmakers JA, Repnik K, Schieck M, Sio YY, Smyth RL, Szalai C, Tantisira KG, Turner S, van der Schee MP, Verhamme KM, Maitland-van der Zee AH. Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium. Pharmacogenomics. 2017 07; 18(10):931-943. PMID: 28639505.
    Citations: 1     Fields:    Translation:Humans
  23. Suratt BT, Ubags NDJ, Rastogi D, Tantisira KG, Marsland BJ, Petrache I, Allen JB, Bates JHT, Holguin F, McCormack MC, Michelakis ED, Black SM, Jain M, Mora AL, Natarajan V, Miller YI, Fessler MB, Birukov KG, Summer RS, Shore SA, Dixon AE. An Official American Thoracic Society Workshop Report: Obesity and Metabolism. An Emerging Frontier in Lung Health and Disease. Ann Am Thorac Soc. 2017 Jun; 14(6):1050-1059. PMID: 28570148.
    Citations: 5     Fields:    Translation:Humans
  24. Park HW, Tantisira KG. Genetic Signatures of Asthma Exacerbation. Allergy Asthma Immunol Res. 2017 May; 9(3):191-199. PMID: 28293925.
    Citations: 3     
  25. Li Y, Morrow J, Raby B, Tantisira K, Weiss ST, Huang W, Qiu W. Detecting disease-associated genomic outcomes using constrained mixture of Bayesian hierarchical models for paired data. PLoS One. 2017; 12(3):e0174602. PMID: 28358896.
    Citations:    Fields:    Translation:Humans
  26. Hardin M, Cho MH, Sharma S, Glass K, Castaldi PJ, McDonald ML, Aschard H, Senter-Sylvia J, Tantisira K, Weiss ST, Hersh CP, Morrow JD, Lomas D, Agusti A, Bakke P, Gulsvik A, O'Connor GT, Dupuis J, Hokanson J, Crapo JD, Beaty TH, Laird N, Silverman EK, DeMeo DL. Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women. Am J Respir Cell Mol Biol. 2017 03; 56(3):332-341. PMID: 27854507.
    Citations: 2     Fields:    Translation:Humans
  27. McGeachie MJ, Davis JS, Kho AT, Dahlin A, Sordillo JE, Sun M, Lu Q, Weiss ST, Tantisira KG. Asthma remission: Predicting future airways responsiveness using an miRNA network. J Allergy Clin Immunol. 2017 Aug; 140(2):598-600.e8. PMID: 28238746.
    Citations: 1     Fields:    
  28. Wang AL, Tantisira KG. Personalized management of asthma exacerbations: lessons from genetic studies. Expert Rev Precis Med Drug Dev. 2016; 1(6):487-495. PMID: 29051920.
    Citations:    
  29. McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Strunk RC, Weiss ST. Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma. Am J Respir Crit Care Med. 2016 12 15; 194(12):1465-1474. PMID: 27367781.
    Citations: 4     Fields:    Translation:Humans
  30. McGeachie MJ, Clemmer GL, Croteau-Chonka DC, Castaldi PJ, Cho MH, Sordillo JE, Lasky-Su JA, Raby BA, Tantisira KG, Weiss ST. Whole genome prediction and heritability of childhood asthma phenotypes. Immun Inflamm Dis. 2016 12; 4(4):487-496. PMID: 27980782.
    Citations:    Fields:    Translation:Humans
  31. Kho AT, Sharma S, Davis JS, Spina J, Howard D, McEnroy K, Moore K, Sylvia J, Qiu W, Weiss ST, Tantisira KG. Circulating MicroRNAs: Association with Lung Function in Asthma. PLoS One. 2016; 11(6):e0157998. PMID: 27362794; PMCID: PMC4928864.
    Citations: 3     Fields:    Translation:Humans
  32. Kho AT, Chhabra D, Sharma S, Qiu W, Carey VJ, Gaedigk R, Vyhlidal CA, Leeder JS, Tantisira KG, Weiss ST. Age, Sexual Dimorphism, and Disease Associations in the Developing Human Fetal Lung Transcriptome. Am J Respir Cell Mol Biol. 2016 06; 54(6):814-21. PMID: 26584061.
    Citations: 8     Fields:    Translation:HumansCells
  33. Tam E, Miike R, Labrenz S, Sutton AJ, Elias T, Davis J, Chen YL, Tantisira K, Dockery D, Avol E. Volcanic air pollution over the Island of Hawai'i: Emissions, dispersal, and composition. Association with respiratory symptoms and lung function in Hawai'i Island school children. Environ Int. 2016 Jul-Aug; 92-93:543-52. PMID: 27197039.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  34. McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Weiss ST, Strunk RC. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med. 2016 May 12; 374(19):1842-1852. PMID: 27168434.
    Citations: 32     Fields:    Translation:Humans
  35. Park HW, Song WJ, Chang YS, Cho SH, Datta S, Weiss ST, Tantisira KG. Bronchodilator response following methacholine-induced bronchoconstriction predicts acute asthma exacerbations. Eur Respir J. 2016 07; 48(1):104-14. PMID: 27076579.
    Citations: 1     Fields:    Translation:Humans
  36. Park HW, Tse S, Yang W, Kelly HW, Kaste SC, Pui CH, Relling MV, Tantisira KG. A genetic factor associated with low final bone mineral density in children after a long-term glucocorticoids treatment. Pharmacogenomics J. 2017 03; 17(2):180-185. PMID: 26856247.
    Citations: 1     Fields:    Translation:Humans
  37. Haas DM, Lai D, Sharma S, Then J, Kho A, Flockhart DA, Tantisira K, Foroud T. Steroid Pathway Genes and Neonatal Respiratory Distress After Betamethasone Use in Anticipated Preterm Birth. Reprod Sci. 2016 May; 23(5):680-6. PMID: 26507871.
    Citations:    Fields:    Translation:HumansCells
  38. Cornejo S, Tantisira K, Raby BA, Weiss ST, Kaplan F. Nuclear bioavailability of the glucocorticoid receptor in a pediatric asthma cohort with variable corticosteroid responsiveness. Pediatr Res. 2015 Nov; 78(5):505-12. PMID: 26270571.
    Citations: 2     Fields:    Translation:HumansCells
  39. Park JA, Kim JH, Bi D, Mitchel JA, Qazvini NT, Tantisira K, Park CY, McGill M, Kim SH, Gweon B, Notbohm J, Steward R, Burger S, Randell SH, Kho AT, Tambe DT, Hardin C, Shore SA, Israel E, Weitz DA, Tschumperlin DJ, Henske EP, Weiss ST, Manning ML, Butler JP, Drazen JM, Fredberg JJ. Unjamming and cell shape in the asthmatic airway epithelium. Nat Mater. 2015 Oct; 14(10):1040-8. PMID: 26237129; PMCID: PMC4666305.
    Citations: 24     Fields:    Translation:HumansCells
  40. Himes BE, Koziol-White C, Johnson M, Nikolos C, Jester W, Klanderman B, Litonjua AA, Tantisira KG, Truskowski K, MacDonald K, Panettieri RA, Weiss ST. Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma. PLoS One. 2015; 10(7):e0134057. PMID: 26207385; PMCID: PMC4514847.
    Citations: 10     Fields:    Translation:HumansCells
  41. Dahlin A, Denny J, Roden DM, Brilliant MH, Ingram C, Kitchner TE, Linneman JG, Shaffer CM, Weeke P, Xu H, Kubo M, Tamari M, Clemmer GL, Ziniti J, McGeachie MJ, Tantisira KG, Weiss ST, Wu AC. CMTR1 is associated with increased asthma exacerbations in patients taking inhaled corticosteroids. Immun Inflamm Dis. 2015 Dec; 3(4):350-9. PMID: 26734457.
    Citations: 3     Fields:    
  42. Strunk RC, Colvin R, Bacharier LB, Fuhlbrigge A, Forno E, Arbelaez AM, Tantisira KG. Airway Obstruction Worsens in Young Adults with Asthma Who Become Obese. J Allergy Clin Immunol Pract. 2015 Sep-Oct; 3(5):765-71.e2. PMID: 26164807.
    Citations: 5     Fields:    Translation:Humans
  43. Davis JS, Weiss ST, Tantisira KG. Asthma Pharmacogenomics: 2015 Update. Curr Allergy Asthma Rep. 2015 Jul; 15(7):42. PMID: 26143396.
    Citations:    
  44. Dahlin A, Litonjua A, Lima JJ, Tamari M, Kubo M, Irvin CG, Peters SP, Tantisira KG. Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma. PLoS One. 2015; 10(6):e0129385. PMID: 26083242; PMCID: PMC4470685.
    Citations: 5     Fields:    Translation:Humans
  45. McGeachie MJ, Wu AC, Tse SM, Clemmer GL, Sordillo J, Himes BE, Lasky-Su J, Chase RP, Martinez FD, Weeke P, Shaffer CM, Xu H, Denny JC, Roden DM, Panettieri RA, Raby BA, Weiss ST, Tantisira KG. CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies. J Allergy Clin Immunol. 2015 Dec; 136(6):1503-1510. PMID: 26073756.
    Citations: 8     Fields:    Translation:Humans
  46. Dahlin A, Litonjua A, Irvin CG, Peters SP, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genome-wide association study of leukotriene modifier response in asthma. Pharmacogenomics J. 2016 Apr; 16(2):151-7. PMID: 26031901; PMCID: PMC4668236.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  47. Vijverberg SJ, Koster ES, Tavendale R, Leusink M, Koenderman L, Raaijmakers JA, Postma DS, Koppelman GH, Turner SW, Mukhopadhyay S, Tse SM, Tantisira KG, Hawcutt DB, Francis B, Pirmohamed M, Pino-Yanes M, Eng C, Burchard EG, Palmer CN, Maitland-van der Zee AH. ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults. Clin Exp Allergy. 2015 Jun; 45(6):1051-9. PMID: 25616159; PMCID: PMC4461653.
    Citations: 7     Fields:    Translation:Humans
  48. Park HW, Ge B, Tse S, Grundberg E, Pastinen T, Kelly HW, Tantisira KG. Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts. J Allergy Clin Immunol. 2015 Nov; 136(5):1240-6.e1-8. PMID: 26025128.
    Citations: 1     Fields:    Translation:HumansCells
  49. Clemmer GL, Wu AC, Rosner B, McGeachie MJ, Litonjua AA, Tantisira KG, Weiss ST. Measuring the corticosteroid responsiveness endophenotype in asthmatic patients. J Allergy Clin Immunol. 2015 Aug; 136(2):274-81.e8. PMID: 25951964; PMCID: PMC4530065.
    Citations: 8     Fields:    Translation:Humans
  50. Sharma S, Kho AT, Chhabra D, Qiu W, Gaedigk R, Vyhlidal CA, Leeder JS, Barraza-Villarreal A, London SJ, Gilliland F, Raby BA, Weiss ST, Tantisira KG. Glucocorticoid genes and the developmental origins of asthma susceptibility and treatment response. Am J Respir Cell Mol Biol. 2015 May; 52(5):543-53. PMID: 25192440; PMCID: PMC4491138.
    Citations: 4     Fields:    Translation:HumansAnimals
  51. Israel E, Lasky-Su J, Markezich A, Damask A, Szefler SJ, Schuemann B, Klanderman B, Sylvia J, Kazani S, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Tantisira KG. Genome-wide association study of short-acting ß2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3. Am J Respir Crit Care Med. 2015 Mar 01; 191(5):530-7. PMID: 25562107; PMCID: PMC4384768.
    Citations: 2     Fields:    Translation:HumansCells
  52. Wang Y, Tong C, Wang Z, Wang Z, Mauger D, Tantisira KG, Israel E, Szefler SJ, Chinchilli VM, Boushey HA, Lazarus SC, Lemanske RF, Wu R. Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma. Pharmacogenomics J. 2015 Oct; 15(5):422-9. PMID: 25601762.
    Citations: 1     Fields:    Translation:Humans
  53. Sharma A, Menche J, Huang CC, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, Barnathan E, Liu H, Panettieri RA, Tantisira KG, Qiu W, Raby BA, Silverman EK, Vidal M, Weiss ST, Barabási AL. A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma. Hum Mol Genet. 2015 Jun 01; 24(11):3005-20. PMID: 25586491; PMCID: PMC4447811.
    Citations: 24     Fields:    Translation:HumansCells
  54. Chhibber A, Kroetz DL, Tantisira KG, McGeachie M, Cheng C, Plenge R, Stahl E, Sadee W, Ritchie MD, Pendergrass SA. Genomic architecture of pharmacological efficacy and adverse events. Pharmacogenomics. 2014 Dec; 15(16):2025-48. PMID: 25521360; PMCID: PMC4308414.
    Citations: 8     Fields:    Translation:Humans
  55. Chhabra D, Sharma S, Kho AT, Gaedigk R, Vyhlidal CA, Leeder JS, Morrow J, Carey VJ, Weiss ST, Tantisira KG, DeMeo DL. Fetal lung and placental methylation is associated with in utero nicotine exposure. Epigenetics. 2014 Nov; 9(11):1473-84. PMID: 25482056; PMCID: PMC4623268.
    Citations: 14     Fields:    Translation:HumansCellsPHPublic Health
  56. Park HW, Tantisira KG, Weiss ST. Pharmacogenomics in asthma therapy: where are we and where do we go? Annu Rev Pharmacol Toxicol. 2015; 55:129-47. PMID: 25292431.
    Citations: 3     Fields:    Translation:HumansAnimals
  57. Wu K, Gamazon ER, Im HK, Geeleher P, White SR, Solway J, Clemmer GL, Weiss ST, Tantisira KG, Cox NJ, Ratain MJ, Huang RS. Genome-wide interrogation of longitudinal FEV1 in children with asthma. Am J Respir Crit Care Med. 2014 Sep 15; 190(6):619-27. PMID: 25221879; PMCID: PMC4214107.
    Citations: 4     Fields:    Translation:HumansCells
  58. Himes BE, Jiang X, Wagner P, Hu R, Wang Q, Klanderman B, Whitaker RM, Duan Q, Lasky-Su J, Nikolos C, Jester W, Johnson M, Panettieri RA, Tantisira KG, Weiss ST, Lu Q. RNA-Seq transcriptome profiling identifies CRISPLD2 as a glucocorticoid responsive gene that modulates cytokine function in airway smooth muscle cells. PLoS One. 2014; 9(6):e99625. PMID: 24926665.
    Citations: 25     Fields:    Translation:HumansCells
  59. Qiu W, Rogers AJ, Damask A, Raby BA, Klanderman BJ, Duan QL, Tyagi S, Niu S, Anderson C, Cahir-Mcfarland E, Mariani TJ, Carey V, Tantisira KG. Pharmacogenomics: novel loci identification via integrating gene differential analysis and eQTL analysis. Hum Mol Genet. 2014 Sep 15; 23(18):5017-24. PMID: 24770851; PMCID: PMC4140460.
    Citations: 4     Fields:    Translation:HumansCells
  60. Sharma S, Chhabra D, Kho AT, Hayden LP, Tantisira KG, Weiss ST. The genomic origins of asthma. Thorax. 2014 May; 69(5):481-7. PMID: 24668408; PMCID: PMC4343201.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  61. Hu R, Pan W, Fedulov AV, Jester W, Jones MR, Weiss ST, Panettieri RA, Tantisira K, Lu Q. MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway. FASEB J. 2014 May; 28(5):2347-57. PMID: 24522205; PMCID: PMC3986841.
    Citations: 21     Fields:    Translation:HumansCells
  62. Park HW, Dahlin A, Tse S, Duan QL, Schuemann B, Martinez FD, Peters SP, Szefler SJ, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J Allergy Clin Immunol. 2014 Mar; 133(3):664-9.e5. PMID: 24486069; PMCID: PMC4112383.
    Citations: 7     Fields:    Translation:Humans
  63. Wu AC, Himes BE, Lasky-Su J, Litonjua A, Peters SP, Lima J, Kubo M, Tamari M, Nakamura Y, Qiu W, Weiss ST, Tantisira K. Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics. J Allergy Clin Immunol. 2014 Mar; 133(3):723-8.e3. PMID: 24280104.
    Citations: 1     Fields:    Translation:HumansCells
  64. Kho AT, Sharma S, Qiu W, Gaedigk R, Klanderman B, Niu S, Anderson C, Leeder JS, Weiss ST, Tantisira KG. Vitamin D related genes in lung development and asthma pathogenesis. BMC Med Genomics. 2013 Nov 05; 6:47. PMID: 24188128; PMCID: PMC4228235.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  65. Bolotin E, Armendariz A, Kim K, Heo SJ, Boffelli D, Tantisira K, Rotter JI, Krauss RM, Medina MW. Statin-induced changes in gene expression in EBV-transformed and native B-cells. Hum Mol Genet. 2014 Mar 01; 23(5):1202-10. PMID: 24179175; PMCID: PMC3919007.
    Citations: 3     Fields:    Translation:HumansCells
  66. Himes BE, Qiu W, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Nieuwenhuis MA, Postma DS, Vonk JM, Rafaels N, Hansel NN, Barnes K, Raby B, Tantisira KG, Weiss ST. ITGB5 and AGFG1 variants are associated with severity of airway responsiveness. BMC Med Genet. 2013 Aug 28; 14:86. PMID: 23984888; PMCID: PMC3765944.
    Citations: 3     Fields:    Translation:Humans
  67. McGeachie MJ, Stahl EA, Himes BE, Pendergrass SA, Lima JJ, Irvin CG, Peters SP, Ritchie MD, Plenge RM, Tantisira KG. Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes. Pharmacogenet Genomics. 2013 Jun; 23(6):324-8. PMID: 23532052; PMCID: PMC3767309.
    Citations: 5     Fields:    Translation:Humans
  68. Tse SM, Gold DR, Sordillo JE, Hoffman EB, Gillman MW, Rifas-Shiman SL, Fuhlbrigge AL, Tantisira KG, Weiss ST, Litonjua AA. Diagnostic accuracy of the bronchodilator response in children. J Allergy Clin Immunol. 2013 Sep; 132(3):554-559.e5. PMID: 23683464.
    Citations: 11     Fields:    Translation:Humans
  69. Duan QL, Lasky-Su J, Himes BE, Qiu W, Litonjua AA, Damask A, Lazarus R, Klanderman B, Irvin CG, Peters SP, Hanrahan JP, Lima JJ, Martinez FD, Mauger D, Chinchilli VM, Soto-Quiros M, Avila L, Celedón JC, Lange C, Weiss ST, Tantisira KG. A genome-wide association study of bronchodilator response in asthmatics. Pharmacogenomics J. 2014 Feb; 14(1):41-7. PMID: 23508266; PMCID: PMC3706515.
    Citations: 6     Fields:    Translation:Humans
  70. Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One. 2013; 8(2):e56179. PMID: 23457522; PMCID: PMC3572953.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  71. Blake K, Cury JD, Hossain J, Tantisira K, Wang J, Mougey E, Lima J. Methacholine PC20 in African Americans and whites with asthma with homozygous genotypes at ADRB2 codon 16. Pulm Pharmacol Ther. 2013 Jun; 26(3):342-7. PMID: 23384627; PMCID: PMC3624039.
    Citations: 1     Fields:    Translation:Humans
  72. Vyhlidal CA, Riffel AK, Haley KJ, Sharma S, Dai H, Tantisira KG, Weiss ST, Leeder JS. Cotinine in human placenta predicts induction of gene expression in fetal tissues. Drug Metab Dispos. 2013 Feb; 41(2):305-11. PMID: 23209192; PMCID: PMC3558855.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  73. Lasky-Su J, Himes BE, Raby BA, Klanderman BJ, Sylvia JS, Lange C, Melen E, Martinez FD, Israel E, Gauderman J, Gilliland F, Sleiman P, Hakonarson H, Celedón JC, Soto-Quiros M, Avila L, Lima JJ, Irvin CG, Peters SP, Boushey H, Chinchilli VM, Mauger D, Tantisira K, Weiss ST. HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults. Clin Exp Allergy. 2012 Dec; 42(12):1724-33. PMID: 23181788.
    Citations: 15     Fields:    Translation:Humans
  74. Carpe N, Mandeville I, Kho AT, Qiu W, Martin JG, Tantisira KG, Raby BA, Weiss ST, Kaplan F. Maternal allergen exposure reprograms the developmental lung transcriptome in atopic and normoresponsive rat pups. Am J Physiol Lung Cell Mol Physiol. 2012 Nov 15; 303(10):L899-911. PMID: 22983352; PMCID: PMC3517678.
    Citations:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
  75. Dahlin A, Tantisira KG. Integrative systems biology approaches in asthma pharmacogenomics. Pharmacogenomics. 2012 Sep; 13(12):1387-404. PMID: 22966888; PMCID: PMC3553555.
    Citations: 5     Fields:    Translation:HumansAnimals
  76. Wu AC, Tantisira K, Li L, Fuhlbrigge AL, Weiss ST, Litonjua A. Effect of vitamin D and inhaled corticosteroid treatment on lung function in children. Am J Respir Crit Care Med. 2012 Sep 15; 186(6):508-13. PMID: 22798322; PMCID: PMC3480528.
    Citations: 35     Fields:    Translation:Humans
  77. Himes BE, Jiang X, Hu R, Wu AC, Lasky-Su JA, Klanderman BJ, Ziniti J, Senter-Sylvia J, Lima JJ, Irvin CG, Peters SP, Meyers DA, Bleecker ER, Kubo M, Tamari M, Nakamura Y, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Hanrahan JP, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Panettieri RA, Markezich A, Israel E, Carey VJ, Tantisira KG, Litonjua AA, Lu Q, Weiss ST. Genome-wide association analysis in asthma subjects identifies SPATS2L as a novel bronchodilator response gene. PLoS Genet. 2012 Jul; 8(7):e1002824. PMID: 22792082.
    Citations: 28     Fields:    Translation:HumansCells
  78. McGeachie MJ, Wu AC, Chang HH, Lima JJ, Peters SP, Tantisira KG. Predicting inhaled corticosteroid response in asthma with two associated SNPs. Pharmacogenomics J. 2013 Aug; 13(4):306-11. PMID: 22641026; PMCID: PMC3434304.
    Citations: 8     Fields:    Translation:Humans
  79. Tse SM, Kelly HW, Litonjua AA, Van Natta ML, Weiss ST, Tantisira KG. Corticosteroid use and bone mineral accretion in children with asthma: effect modification by vitamin D. J Allergy Clin Immunol. 2012 Jul; 130(1):53-60.e4. PMID: 22608570.
    Citations: 15     Fields:    Translation:Humans
  80. Forno E, Lasky-Su J, Himes B, Howrylak J, Ramsey C, Brehm J, Klanderman B, Ziniti J, Melén E, Pershagen G, Wickman M, Martinez F, Mauger D, Sorkness C, Tantisira K, Raby BA, Weiss ST, Celedón JC. Genome-wide association study of the age of onset of childhood asthma. J Allergy Clin Immunol. 2012 Jul; 130(1):83-90.e4. PMID: 22560479.
    Citations: 9     Fields:    Translation:Humans
  81. Tantisira KG, Damask A, Szefler SJ, Schuemann B, Markezich A, Su J, Klanderman B, Sylvia J, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Israel E. Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus. Am J Respir Crit Care Med. 2012 Jun 15; 185(12):1286-91. PMID: 22538805; PMCID: PMC3381232.
    Citations: 19     Fields:    Translation:Humans
  82. Mougey EB, Chen C, Tantisira KG, Blake KV, Peters SP, Wise RA, Weiss ST, Lima JJ. Pharmacogenetics of asthma controller treatment. Pharmacogenomics J. 2013 Jun; 13(3):242-50. PMID: 22370858.
    Citations: 6     Fields:    Translation:Humans
  83. Duan QL, Du R, Lasky-Su J, Klanderman BJ, Partch AB, Peters SP, Irvin CG, Hanrahan JP, Lima JJ, Blake KV, Liggett SB, Litonjua AA, Tantisira KG. A polymorphism in the thyroid hormone receptor gene is associated with bronchodilator response in asthmatics. Pharmacogenomics J. 2013 Apr; 13(2):130-6. PMID: 22212731; PMCID: PMC3349771.
    Citations: 8     Fields:    Translation:HumansCells
  84. Du R, Litonjua AA, Tantisira KG, Lasky-Su J, Sunyaev SR, Klanderman BJ, Celedón JC, Avila L, Soto-Quiros ME, Weiss ST. Genome-wide association study reveals class I MHC-restricted T cell-associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations. J Allergy Clin Immunol. 2012 Feb; 129(2):368-73, 373.e1-5. PMID: 22051697.
    Citations: 9     Fields:    Translation:Humans
  85. Tse SM, Tantisira K, Weiss ST. The pharmacogenetics and pharmacogenomics of asthma therapy. Pharmacogenomics J. 2011 Dec; 11(6):383-92. PMID: 21987090; PMCID: PMC3298891.
    Citations: 13     Fields:    Translation:Humans
  86. Tantisira KG, Lasky-Su J, Harada M, Murphy A, Litonjua AA, Himes BE, Lange C, Lazarus R, Sylvia J, Klanderman B, Duan QL, Qiu W, Hirota T, Martinez FD, Mauger D, Sorkness C, Szefler S, Lazarus SC, Lemanske RF, Peters SP, Lima JJ, Nakamura Y, Tamari M, Weiss ST. Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med. 2011 Sep 29; 365(13):1173-83. PMID: 21991891; PMCID: PMC3667396.
    Citations: 73     Fields:    Translation:Humans
  87. Wu R, Tong C, Wang Z, Mauger D, Tantisira K, Szefler SJ, Chinchilli VM, Israel E. A conceptual framework for pharmacodynamic genome-wide association studies in pharmacogenomics. Drug Discov Today. 2011 Oct; 16(19-20):884-90. PMID: 21920452; PMCID: PMC4029408.
    Citations: 4     Fields:    Translation:Humans
  88. Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Doi S, Fujita K, Miyatake A, Enomoto T, Miyagawa T, Adachi M, Tanaka H, Niimi A, Matsumoto H, Ito I, Masuko H, Sakamoto T, Hizawa N, Taniguchi M, Lima JJ, Irvin CG, Peters SP, Himes BE, Litonjua AA, Tantisira KG, Weiss ST, Kamatani N, Nakamura Y, Tamari M. Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. Nat Genet. 2011 Jul 31; 43(9):893-6. PMID: 21804548; PMCID: PMC4310726.
    Citations: 98     Fields:    Translation:HumansCells
  89. Haley KJ, Lasky-Su J, Manoli SE, Smith LA, Shahsafaei A, Weiss ST, Tantisira K. RUNX transcription factors: association with pediatric asthma and modulated by maternal smoking. Am J Physiol Lung Cell Mol Physiol. 2011 Nov; 301(5):L693-701. PMID: 21803869; PMCID: PMC3213989.
    Citations: 16     Fields:    Translation:HumansAnimalsPHPublic Health
  90. Xu M, Tantisira KG, Wu A, Litonjua AA, Chu JH, Himes BE, Damask A, Weiss ST. Genome Wide Association Study to predict severe asthma exacerbations in children using random forests classifiers. BMC Med Genet. 2011 Jun 30; 12:90. PMID: 21718536; PMCID: PMC3148549.
    Citations: 20     Fields:    Translation:Humans
  91. Melén E, Kho AT, Sharma S, Gaedigk R, Leeder JS, Mariani TJ, Carey VJ, Weiss ST, Tantisira KG. Expression analysis of asthma candidate genes during human and murine lung development. Respir Res. 2011 Jun 23; 12:86. PMID: 21699702; PMCID: PMC3141421.
    Citations: 25     Fields:    Translation:HumansAnimals
  92. Wu AC, Davis R, Tantisira K, Dutta-Linn MM, Hemmes M, Weiss ST. Acceptance of Asthma Pharmacogenetic Study by Children and Adults. J Pharmacogenomics Pharmacoproteomics. 2011 Apr 04; 2(103). PMID: 23560243.
    Citations: 1     
  93. Wu AC, Tantisira K, Li L, Schuemann B, Weiss ST, Fuhlbrigge AL. Predictors of symptoms are different from predictors of severe exacerbations from asthma in children. Chest. 2011 Jul; 140(1):100-107. PMID: 21292760; PMCID: PMC3130529.
    Citations: 21     Fields:    Translation:Humans
  94. Grundberg E, Adoue V, Kwan T, Ge B, Duan QL, Lam KC, Koka V, Kindmark A, Weiss ST, Tantisira K, Mallmin H, Raby BA, Nilsson O, Pastinen T. Global analysis of the impact of environmental perturbation on cis-regulation of gene expression. PLoS Genet. 2011 Jan 20; 7(1):e1001279. PMID: 21283786; PMCID: PMC3024267.
    Citations: 49     Fields:    Translation:HumansCellsPHPublic Health
  95. Duan QL, Gaume BR, Hawkins GA, Himes BE, Bleecker ER, Klanderman B, Irvin CG, Peters SP, Meyers DA, Hanrahan JP, Lima JJ, Litonjua AA, Tantisira KG, Liggett SB. Regulatory haplotypes in ARG1 are associated with altered bronchodilator response. Am J Respir Crit Care Med. 2011 Feb 15; 183(4):449-54. PMID: 20851928; PMCID: PMC3056223.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
  96. Harada M, Hirota T, Jodo AI, Hitomi Y, Sakashita M, Tsunoda T, Miyagawa T, Doi S, Kameda M, Fujita K, Miyatake A, Enomoto T, Noguchi E, Masuko H, Sakamoto T, Hizawa N, Suzuki Y, Yoshihara S, Adachi M, Ebisawa M, Saito H, Matsumoto K, Nakajima T, Mathias RA, Rafaels N, Barnes KC, Himes BE, Duan QL, Tantisira KG, Weiss ST, Nakamura Y, Ziegler SF, Tamari M. Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma. Am J Respir Cell Mol Biol. 2011 Jun; 44(6):787-93. PMID: 20656951; PMCID: PMC3159073.
    Citations: 47     Fields:    Translation:HumansCells
  97. Carpe N, Mandeville I, Ribeiro L, Ponton A, Martin JG, Kho AT, Chu JH, Tantisira K, Weiss ST, Raby BA, Kaplan F. Genetic influences on asthma susceptibility in the developing lung. Am J Respir Cell Mol Biol. 2010 Dec; 43(6):720-30. PMID: 20118217; PMCID: PMC3159089.
    Citations: 5     Fields:    Translation:AnimalsCells
  98. Welsh M, Mangravite L, Medina MW, Tantisira K, Zhang W, Huang RS, McLeod H, Dolan ME. Pharmacogenomic discovery using cell-based models. Pharmacol Rev. 2009 Dec; 61(4):413-29. PMID: 20038569; PMCID: PMC2802425.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  99. Sharma S, Tantisira K, Carey V, Murphy AJ, Lasky-Su J, Celedón JC, Lazarus R, Klanderman B, Rogers A, Soto-Quirós M, Avila L, Mariani T, Gaedigk R, Leeder S, Torday J, Warburton D, Raby B, Weiss ST. A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma. Am J Respir Crit Care Med. 2010 Feb 15; 181(4):328-36. PMID: 19926868.
    Citations: 30     Fields:    Translation:Humans
  100. Kho AT, Bhattacharya S, Tantisira KG, Carey VJ, Gaedigk R, Leeder JS, Kohane IS, Weiss ST, Mariani TJ. Transcriptomic analysis of human lung development. Am J Respir Crit Care Med. 2010 Jan 01; 181(1):54-63. PMID: 19815808; PMCID: PMC2797628.
    Citations: 40     Fields:    Translation:Humans
  101. Himes BE, Wu AC, Duan QL, Klanderman B, Litonjua AA, Tantisira K, Ramoni MF, Weiss ST. Predicting response to short-acting bronchodilator medication using Bayesian networks. Pharmacogenomics. 2009 Sep; 10(9):1393-412. PMID: 19761364; PMCID: PMC2804237.
    Citations: 12     Fields:    Translation:Humans
  102. Tantisira KG, Drazen JM. Genetics and pharmacogenetics of the leukotriene pathway. J Allergy Clin Immunol. 2009 Sep; 124(3):422-7. PMID: 19665766; PMCID: PMC2794036.
    Citations: 23     Fields:    Translation:HumansAnimals
  103. Rogers AJ, Tantisira KG, Fuhlbrigge AL, Litonjua AA, Lasky-Su JA, Szefler SJ, Strunk RC, Zeiger RS, Weiss ST. Predictors of poor response during asthma therapy differ with definition of outcome. Pharmacogenomics. 2009 Aug; 10(8):1231-42. PMID: 19663668; PMCID: PMC2746392.
    Citations: 16     Fields:    Translation:Humans
  104. Raby BA, Van Steen K, Lasky-Su J, Tantisira K, Kaplan F, Weiss ST. Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma. Respir Res. 2009 Jul 20; 10:67. PMID: 19619331; PMCID: PMC2724419.
    Citations: 8     Fields:    Translation:Humans
  105. Murphy A, Tantisira KG, Soto-Quirós ME, Avila L, Klanderman BJ, Lake S, Weiss ST, Celedón JC. PRKCA: a positional candidate gene for body mass index and asthma. Am J Hum Genet. 2009 Jul; 85(1):87-96. PMID: 19576566; PMCID: PMC2706964.
    Citations: 21     Fields:    Translation:Humans
  106. Du R, Tantisira K, Carey V, Bhattacharya S, Metje S, Kho AT, Klanderman BJ, Gaedigk R, Lazarus R, Mariani TJ, Leeder JS, Weiss ST. Platform dependence of inference on gene-wise and gene-set involvement in human lung development. BMC Bioinformatics. 2009 Jun 19; 10:189. PMID: 19545372; PMCID: PMC2711081.
    Citations: 2     Fields:    Translation:Humans
  107. Tantisira KG. In asthma, the apple falls faster than the pear. J Allergy Clin Immunol. 2009 May; 123(5):1075-6. PMID: 19410692.
    Citations:    Fields:    Translation:Humans
  108. Tantisira KG, Lima J, Sylvia J, Klanderman B, Weiss ST. 5-lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci. Pharmacogenet Genomics. 2009 Mar; 19(3):244-7. PMID: 19214143; PMCID: PMC2731688.
    Citations: 19     Fields:    Translation:Humans
  109. Hawkins GA, Lazarus R, Smith RS, Tantisira KG, Meyers DA, Peters SP, Weiss ST, Bleecker ER. The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids. J Allergy Clin Immunol. 2009 Jun; 123(6):1376-83.e7. PMID: 19254810; PMCID: PMC4317788.
    Citations: 31     Fields:    Translation:Humans
  110. Tantisira KG, Lima J, Sylvia J, Klanderman B, Weiss ST. 5-lipoxygenase Pharmacogenetics in Asthma: Overlap with CystLTR1 Loci. Pharmacogenet Genomics. 2009; (In Press).
  111. Tantisira KG. Novel approaches to pharmacogenomic investigations. Curr Pharm Des. 2009; 15(32):3732-3. PMID: 19925423.
    Citations:    Fields:    Translation:Humans
  112. Murphy A, Lasky-Su J, Tantisira KG, Litonjua AA, Lange C, Weiss ST. Genome-wide association studies of family data in pharmacogenetics: a case study. Curr Pharm Des. 2009; 15(32):3764-72. PMID: 19925427.
    Citations: 1     Fields:    Translation:Humans
  113. Tantisira K, Weiss S. The pharmacogenetics of asthma treatment. Curr Allergy Asthma Rep. 2009 Jan; 9(1):10-7. PMID: 19063819.
    Citations: 7     Fields:    Translation:Humans
  114. Duan QL, Tantisira KG. Pharmacogenetics of asthma therapy. Curr Pharm Des. 2009; 15(32):3742-53. PMID: 19925425.
    Citations: 3     Fields:    Translation:HumansAnimals
  115. Lima JJ, Blake KV, Tantisira KG, Weiss ST. Pharmacogenetics of asthma. Curr Opin Pulm Med. 2009 Jan; 15(1):57-62. PMID: 19077707; PMCID: PMC2754311.
    Citations: 22     Fields:    Translation:Humans
  116. Wu AC, Tantisira K, Li L, Schuemann B, Weiss S. Repeatability of response to asthma medications. J Allergy Clin Immunol. 2009 Feb; 123(2):385-90. PMID: 19064281; PMCID: PMC2980870.
    Citations: 8     Fields:    Translation:Humans
  117. Sharma S, Litonjua AA, Tantisira KG, Fuhlbrigge AL, Szefler SJ, Strunk RC, Zeiger RS, Murphy AJ, Weiss ST. Clinical predictors and outcomes of consistent bronchodilator response in the childhood asthma management program. J Allergy Clin Immunol. 2008 Nov; 122(5):921-928.e4. PMID: 18848350; PMCID: PMC2947830.
    Citations: 21     Fields:    Translation:Humans
  118. Tantisira KG, Lazarus R, Litonjua AA, Klanderman B, Weiss ST. Chromosome 17: association of a large inversion polymorphism with corticosteroid response in asthma. Pharmacogenet Genomics. 2008 Aug; 18(8):733-7. PMID: 18622266; PMCID: PMC3225071.
    Citations: 14     Fields:    Translation:HumansCells
  119. Litonjua AA, Lasky-Su J, Schneiter K, Tantisira KG, Lazarus R, Klanderman B, Lima JJ, Irvin CG, Peters SP, Hanrahan JP, Liggett SB, Hawkins GA, Meyers DA, Bleecker ER, Lange C, Weiss ST. ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts. Am J Respir Crit Care Med. 2008 Oct 01; 178(7):688-94. PMID: 18617639; PMCID: PMC2556451.
    Citations: 34     Fields:    Translation:Humans
  120. Tantisira K. Genetic variation in FCER2: implications for children with asthma. Pharmacogenomics. 2008 Jul; 9(7):805-7. PMID: 18597642.
    Citations: 1     Fields:    Translation:Humans
  121. Jones TS, Kaste SC, Liu W, Cheng C, Yang W, Tantisira KG, Pui CH, Relling MV. CRHR1 polymorphisms predict bone density in survivors of acute lymphoblastic leukemia. J Clin Oncol. 2008 Jun 20; 26(18):3031-7. PMID: 18565889.
    Citations: 13     Fields:    Translation:Humans
  122. Jones TS, Kaste SC, Liu W, Cheng C, Yang W, Tantisira KG, Ching-Hon P, Relling MV. Corticotropin Releasing Hormone Receptor-1 (CRHR1) Polymorphisms Predict Bone Density in Acute Lymphoblastic Leukemia Survivors. J Clin Oncology. 2008; 26(18):3031-7.
  123. Poon AH, Tantisira KG, Litonjua AA, Lazarus R, Xu J, Lasky-Su J, Lima JJ, Irvin CG, Hanrahan JP, Lange C, Weiss ST. Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma. Pharmacogenet Genomics. 2008 May; 18(5):373-82. PMID: 18408560; PMCID: PMC3208318.
    Citations: 14     Fields:    Translation:Humans
  124. Tantisira KG, Colvin R, Tonascia J, Strunk RC, Weiss ST, Fuhlbrigge AL. Airway responsiveness in mild to moderate childhood asthma: sex influences on the natural history. Am J Respir Crit Care Med. 2008 Aug 15; 178(4):325-31. PMID: 18420965; PMCID: PMC2542438.
    Citations: 29     Fields:    Translation:Humans
  125. Tantisira KG, Silverman ES, Mariani TJ, Xu J, Richter BG, Klanderman BJ, Litonjua AA, Lazarus R, Rosenwasser LJ, Fuhlbrigge AL, Weiss ST. FCER2: a pharmacogenetic basis for severe exacerbations in children with asthma. J Allergy Clin Immunol. 2007 Dec; 120(6):1285-91. PMID: 17980418.
    Citations: 39     Fields:    Translation:Humans
  126. Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I. The pharmacogenetics research network: from SNP discovery to clinical drug response. Clin Pharmacol Ther. 2007 Mar; 81(3):328-45. PMID: 17339863; PMCID: PMC5006950.
    Citations: 59     Fields:    Translation:HumansAnimals
  127. Ly NP, Rifas-Shiman SL, Litonjua AA, Tzianabos AO, Schaub B, Ruiz-Pérez B, Tantisira KG, Finn PW, Gillman MW, Weiss ST, Gold DR. Cord blood cytokines and acute lower respiratory illnesses in the first year of life. Pediatrics. 2007 Jan; 119(1):e171-8. PMID: 17145902; PMCID: PMC1994927.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  128. Tantisira KG, Weiss ST. The pharmacogenetics of asthma therapy. Curr Drug Targets. 2006 Dec; 7(12):1697-708. PMID: 17168844.
    Citations:    Fields:    Translation:HumansCells
  129. Tantisira KG, Gold DR. Adipositas in Infants and Children: A New Disease on the Horizon. U. Frey, J. Gerritsen, editors. European Respiratory Monograph: Respiratory Diseases in Infants and Children. 2006; 11(37):314-344.
  130. Hawkins GA, Tantisira K, Meyers DA, Ampleford EJ, Klanderman B, Liggett SB, Peters SP, Weiss ST, Bleecker ER. Sequence, Haplotype and Association Analysis of ADR{beta}2 in Multi-Ethnic Asthma Case/Control Subjects. Am J Respir Crit Care Med. 2006; 174(10):1101-9.
  131. Litonjua AA, Rifas-Shiman SL, Ly NP, Tantisira KG, Rich-Edwards JW, Camargo CA, Weiss ST, Gillman MW, Gold DR. Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 y of age. Am J Clin Nutr. 2006 Oct; 84(4):903-11. PMID: 17023719.
    Citations: 45     Fields:    Translation:Humans
  132. Tantisira KG, Bleecker ER. Pharmacogenetics. D. Postma, S.T. Weiss, editors. Genetics of Asthma and Chronic Obstructive Pulmonary Disease. 2006; 218:357-397.
  133. Hawkins GA, Tantisira K, Meyers DA, Ampleford EJ, Moore WC, Klanderman B, Liggett SB, Peters SP, Weiss ST, Bleecker ER. Sequence, haplotype, and association analysis of ADRbeta2 in a multiethnic asthma case-control study. Am J Respir Crit Care Med. 2006 Nov 15; 174(10):1101-9. PMID: 16931635; PMCID: PMC2648111.
    Citations: 47     Fields:    Translation:Humans
  134. Gold DR, Willwerth BM, Tantisira KG, Palmer LJ, Finn PW, Perkins DL, Schroeter C, Gibbons F, Schuab B, Campos H, Gillman MW, Weiss ST. Association of Cord Blood Fatty Acids with Lymphocyte Proliferation, IL-13 and Interferon Gamma. J Allergy Clin Immunol. 2006; 117(4):931-8.
  135. Tantisira KG, Fuhlbrigge AL, Tonascia J, Van Natta M, Zeiger RS, Strunk RC, Szefler SJ, Weiss ST. Bronchodilation and bronchoconstriction: predictors of future lung function in childhood asthma. J Allergy Clin Immunol. 2006 Jun; 117(6):1264-71. PMID: 16750985.
    Citations: 26     Fields:    Translation:Humans
  136. Weiss ST, Litonjua AA, Lange C, Lazarus R, Liggett SB, Bleecker ER, Tantisira KG. Overview of the pharmacogenetics of asthma treatment. Pharmacogenomics J. 2006 Sep-Oct; 6(5):311-26. PMID: 16568148.
    Citations: 20     Fields:    Translation:HumansAnimals
  137. Tantisira KG, Schneiter K, Litonjua AA, Lazarus R, Raby B, Silverman EK, Klanderman B, Lange C, Weiss ST. Identification of Novel Asthma Susceptibility Loci Using a Family-Based Screening Approach. Proceedings of the American Thoracic Society. 2006; 3:A351.
  138. Tantisira KG, Schneiter K, Litonjua AA, Su J, Lange C, Klanderman B, Lazarus R, Weiss ST. Asthma Pharmacogenetics: Novel Steroid Response Genes Identified Via a Family-Based Screening Approach. Proceedings of the American Thoracic Society. 2006; 3:A214.
  139. Willwerth BM, Schaub B, Tantisira KG, Gold DR, Palmer LJ, Litonjua AA, Perkins DL, Schroeter C, Gibbons FK, Gillman MW, Weiss ST, Finn PW. Prenatal, perinatal, and heritable influences on cord blood immune responses. Ann Allergy Asthma Immunol. 2006 Mar; 96(3):445-53. PMID: 16597079; PMCID: PMC1562525.
    Citations: 11     Fields:    Translation:HumansCellsPHPublic Health
  140. Gold DR, Willwerth BM, Tantisira KG, Finn PW, Schaub B, Perkins DL, Tzianabos A, Ly NP, Schroeter C, Gibbons F, Campos H, Oken E, Gillman MW, Palmer LJ, Ryan LM, Weiss ST. Associations of cord blood fatty acids with lymphocyte proliferation, IL-13, and IFN-gamma. J Allergy Clin Immunol. 2006 Apr; 117(4):931-8. PMID: 16630954; PMCID: PMC1508138.
    Citations: 7     Fields:    Translation:HumansCells
  141. Lima JJ, Zhang S, Grant A, Shao L, Tantisira KG, Allayee H, Wang J, Sylvester J, Holbrook J, Wise R, Weiss ST, Barnes K. Influence of leukotriene pathway polymorphisms on response to montelukast in asthma. Am J Respir Crit Care Med. 2006 Feb 15; 173(4):379-85. PMID: 16293801; PMCID: PMC2662939.
    Citations: 58     Fields:    Translation:Humans
  142. Tantisira KG, Drazen JM. Pharmacogenetics. EK Silverman, S Shapiro, and ST Weiss, editors. Respiratory Genetics. 2005; 191-216.
  143. Raby BA, Hwang ES, Van Steen K, Tantisira K, Peng S, Litonjua A, Lazarus R, Giallourakis C, Rioux JD, Sparrow D, Silverman EK, Glimcher LH, Weiss ST. T-bet polymorphisms are associated with asthma and airway hyperresponsiveness. Am J Respir Crit Care Med. 2006 Jan 01; 173(1):64-70. PMID: 16179640; PMCID: PMC2662983.
    Citations: 30     Fields:    Translation:Humans
  144. Schaub B, Tantisira KG, Gibbons FK, He H, Litonjua AA, Gillman MW, Weiss S, Perkins DL, Gold DR, Finn PW. Fetal cord blood: aspects of heightened immune responses. J Clin Immunol. 2005 Jul; 25(4):329-37. PMID: 16133989; PMCID: PMC1488727.
    Citations: 10     Fields:    Translation:HumansCells
  145. Litonjua AA, Tantisira KG, Lake S, Lazarus R, Richter BG, Gabriel S, Silverman ES, Weiss ST. Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma. Respir Res. 2005 Jun 03; 6:52. PMID: 15935090; PMCID: PMC1180474.
    Citations: 15     Fields:    Translation:Humans
  146. Tantisira KG, Weiss ST. The pharmacogenetics of asthma: an update. Curr Opin Mol Ther. 2005 Jun; 7(3):209-17. PMID: 15977417.
    Citations: 7     Fields:    Translation:Humans
  147. Tantisira KG, Small KM, Litonjua AA, Weiss ST, Liggett SB. Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways. Hum Mol Genet. 2005 Jun 15; 14(12):1671-7. PMID: 15879435.
    Citations: 30     Fields:    Translation:HumansCellsCTClinical Trials
  148. Tam EK, Kunimoto J, Labrenz S, Sutherland J, Chen YL, Sutton AJ, Elias T, Tantisira K, Dockery DW, Avol E . Concentration and Acidity of Airborne Particulate Matter in Communities on the Big Island of Hawaii. Proceedings of the American Thoracic Society. 2005; 2:A264.
  149. Levy H, Raby BA, Lake S, Tantisira KG, Kwiatkowski D, Lazarus R, Silverman EK, Richter B, Klimecki WT, Vercelli D, Martinez FD, Weiss ST. Association of defensin beta-1 gene polymorphisms with asthma. J Allergy Clin Immunol. 2005 Feb; 115(2):252-8. PMID: 15696078; PMCID: PMC4475026.
    Citations: 20     Fields:    Translation:Humans
  150. Silverman ES, Lake SL, Tantisira KG, Richter BG, Litonjua AA, Lazarus R, Valone J, Shore SA, Weiss ST. Association of corticotropin releasing factor receptor-2 variants with response to inhaled glucocorticoids in asthma. Clinical Pharmacology and Therapeutics. 2005; 77(2):P8.
  151. Tantisira KG, Hwang ES, Raby BA, Silverman ES, Lake SL, Richter BG, Peng SL, Drazen JM, Glimcher LH, Weiss ST. TBX21: a functional variant predicts improvement in asthma with the use of inhaled corticosteroids. Proc Natl Acad Sci U S A. 2004 Dec 28; 101(52):18099-104. PMID: 15604153; PMCID: PMC539815.
    Citations: 41     Fields:    Translation:HumansCellsCTClinical Trials
  152. Licinio J, O'Kirwan F, Irizarry K, Merriman B, Thakur S, Jepson R, Lake S, Tantisira KG, Weiss ST, Wong ML. Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans. Mol Psychiatry. 2004 Dec; 9(12):1075-82. PMID: 15365580.
    Citations: 49     Fields:    Translation:HumansCTClinical Trials
  153. Silverman ES, Breault DT, Vallone J, Subramanian S, Yilmaz AD, Mathew S, Subramaniam V, Tantisira K, Pacák K, Weiss ST, Majzoub JA. Corticotropin-releasing hormone deficiency increases allergen-induced airway inflammation in a mouse model of asthma. J Allergy Clin Immunol. 2004 Oct; 114(4):747-54. PMID: 15480311.
    Citations: 17     Fields:    Translation:Animals
  154. Tantisira K, Klimecki WT, Lazarus R, Palmer LJ, Raby BA, Kwiatkowski DJ, Silverman E, Vercelli D, Martinez FD, Weiss ST. Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma. Genes Immun. 2004 Aug; 5(5):343-6. PMID: 15266299.
    Citations: 23     Fields:    Translation:Humans
  155. Litonjua AA, Silverman EK, Tantisira KG, Sparrow D, Sylvia JS, Weiss ST. Beta 2-adrenergic receptor polymorphisms and haplotypes are associated with airways hyperresponsiveness among nonsmoking men. Chest. 2004 Jul; 126(1):66-74. PMID: 15249444.
    Citations: 14     Fields:    Translation:Humans
  156. Tam EK, Kunimoto J, Labrenz S, Sutherland J, Chen YL, Sutton AJ, Elias T, Avol E, Dockery D, Tantisira K. Hawaii Island Children's Lung Assessment Scientific Study (HICLASS). Neurotoxicology. 2004; 25(4):725-6.
  157. Tantisira KG, Lake S, Silverman ES, Palmer LJ, Lazarus R, Silverman EK, Liggett SB, Gelfand EW, Rosenwasser LJ, Richter B, Israel E, Wechsler M, Gabriel S, Altshuler D, Lander E, Drazen J, Weiss ST. Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. Hum Mol Genet. 2004 Jul 01; 13(13):1353-9. PMID: 15128701.
    Citations: 85     Fields:    Translation:Humans
  158. Weiss ST, Tantisira KG. Diagnostic Assay and Related Products. 2004.
  159. Weiss ST, Lake SL, Silverman ES, Silverman EK, Richter B, Drazen JM, Tantisira KG. Asthma steroid pharmacogenetics: a study strategy to identify replicated treatment responses. Proc Am Thorac Soc. 2004; 1(4):364-7. PMID: 16113459.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  160. Tantisira KG, Litonjua AA, Weiss ST, Fuhlbrigge AL. Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP). Thorax. 2003 Dec; 58(12):1036-41. PMID: 14645968; PMCID: PMC1746552.
    Citations: 67     Fields:    Translation:HumansCTClinical Trials
  161. Silverman ES, Hjoberg J, Palmer LJ, Tantisira KG, Weiss ST, Drazen JM. Application of Pharmacogenetics to the Therapeutics of Asthma. N. Tony Eissa and David Huston, editors. Therapeutic Targets of Airway Inflammation. 2003; 823-838.
  162. Tantisira KG, Willwerth BM, Palmer LJ, Oken E, Finn PW, Perkins D, Schroeter C, Gibbons F, Schuab B, Camargo CA, Gillman MW, Weiss ST, Gold DR. Birth Weight Influences Cord Blood Cytokine Levels. Am J Respir Crit Care Med. 2003; 167:A61.
  163. Lake SL, Lyon H, Tantisira K, Silverman EK, Weiss ST, Laird NM, Schaid DJ. Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous. Hum Hered. 2003; 55(1):56-65. PMID: 12890927.
    Citations: 151     Fields:    Translation:Humans
  164. Baron RM, Palmer LJ, Tantisira K, Gabriel S, Sonna LA, Le L, Hallock A, Libermann TA, Drazen JM, Weiss ST, Silverman ES. DNA sequence variants in epithelium-specific ETS-2 and ETS-3 are not associated with asthma. Am J Respir Crit Care Med. 2002 Oct 01; 166(7):927-32. PMID: 12359648.
    Citations: 5     Fields:    Translation:HumansCells
  165. Tantisira KG, Systrom DM, Ginns LC. An elevated breathing reserve index at the lactate threshold is a predictor of mortality in patients with cystic fibrosis awaiting lung transplantation. Am J Respir Crit Care Med. 2002 Jun 15; 165(12):1629-33. PMID: 12070064.
    Citations: 3     Fields:    Translation:Humans
  166. Stanchina ML, Tantisira KG, Aquino SL, Wain JC, Ginns LC. Association of lung perfusion disparity and mortality in patients with cystic fibrosis awaiting lung transplantation. J Heart Lung Transplant. 2002 Feb; 21(2):217-25. PMID: 11834350.
    Citations: 3     Fields:    Translation:Humans
  167. Tantisira KG, Weiss ST. Childhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses. Respir Res. 2001; 2(6):324-7. PMID: 11737930; PMCID: PMC64800.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  168. Tantisira KG, Weiss ST. Complex interactions in complex traits: obesity and asthma. Thorax. 2001 Sep; 56 Suppl 2:ii64-73. PMID: 11514709; PMCID: PMC1765987.
    Citations: 45     Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.