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Samia Joseph Khoury, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R13NS080494 (KHOURY, SAMIA J.) Sep 1, 2012 - Aug 31, 2013
    11th International Congress of Neuroimmunology
    Role: Principal Investigator
  2. R56AI093838 (KHOURY, SAMIA J.) Aug 15, 2012 - Jul 31, 2014
    Neural Stem Cells and Regulatory T Cells
    Role: Principal Investigator
  3. R01AI067472 (KHOURY, SAMIA J.) Apr 1, 2008 - Sep 30, 2013
    Role: Principal Investigator
  4. R01AI071448 (KHOURY, SAMIA J.) Apr 1, 2007 - Mar 31, 2011
    Impact of IFN-gamma on Neural Stem Cell Repair Potential in EAE
    Role: Principal Investigator
  5. R56AI058680 (KHOURY, SAMIA J.) Dec 1, 2003 - May 31, 2011
    Role and mechanism of negative costimulatory pathways in EAE
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Darwish H, Zeinoun P, Farran N, Ghusn H, Yamout B, Khoury SJ. The Brief International Cognitive Assessment in Multiple Sclerosis (BICAMS): Validation in Arabic and Lebanese Normative Values. J Int Neuropsychol Soc. 2021 Feb 10; 1-10. PMID: 33563350.
    Citations:    Fields:    
  2. Jaafar N, Khoueiry M, Khoury SJ, Makki A. Rare Case of Spinal Neurosarcoidosis with Concomitant Epidural Lipomatosis. Case Rep Neurol Med. 2021; 2021:5952724. PMID: 33604089.
  3. Khoury SJ. Progressive Multiple Sclerosis. Ann Neurol. 2020 09; 88(3):436-437. PMID: 32628321.
    Citations:    Fields:    Translation:Humans
  4. Zeinoun P, Farran N, Khoury SJ, Darwish H. Development, psychometric properties, and pilot norms of the first Arabic indigenous memory test: The Verbal Memory Arabic Test (VMAT). J Clin Exp Neuropsychol. 2020 07; 42(5):505-515. PMID: 32567997.
    Citations:    Fields:    Translation:Humans
  5. Amor S, Baker D, Khoury SJ, Schmierer K, Giovanonni G. SARS-CoV-2 and Multiple Sclerosis: Not All Immune Depleting DMTs are Equal or Bad. Ann Neurol. 2020 06; 87(6):794-797. PMID: 32383812.
    Citations: 15     Fields:    Translation:HumansCellsPHPublic Health
  6. Darwish H, Farran N, Hannoun S, Tadros N, Yamout B, El Ayoubi NK, Khoury SJ. Serum vitamin D level is associated with speed of processing in multiple sclerosis patients. J Steroid Biochem Mol Biol. 2020 06; 200:105628. PMID: 32061642.
    Citations:    Fields:    Translation:Humans
  7. Mayssam EN, Eid C, Khoury SJ, Hannoun S. "No evidence of disease activity": Is it an aspirational therapeutic goal in multiple sclerosis? Mult Scler Relat Disord. 2020 May; 40:101935. PMID: 31951861.
    Citations:    Fields:    Translation:Humans
  8. Tamim H, Zeineldine S, Tabbara F, Khoury S, Akiki Z, Khansa S, Taher A. Structure and evaluation of a residency research program in a university hospital. BMC Med Educ. 2019 Nov 06; 19(1):406. PMID: 31694614.
    Citations:    Fields:    Translation:Humans
  9. Yamout B, Sahraian M, Bohlega S, Al-Jumah M, Goueider R, Dahdaleh M, Inshasi J, Hashem S, Alsharoqi I, Khoury S, Alkhawajah M, Koussa S, Al Khaburi J, Almahdawi A, Alsaadi T, Slassi E, Daodi S, Zakaria M, Alroughani R. Consensus recommendations for the diagnosis and treatment of multiple sclerosis: 2019 revisions to the MENACTRIMS guidelines. Mult Scler Relat Disord. 2020 Jan; 37:101459. PMID: 31670208.
    Citations: 5     Fields:    Translation:Humans
  10. Maalouf FT, Alamiri B, Atweh S, Becker AE, Cheour M, Darwish H, Ghandour LA, Ghuloum S, Hamze M, Karam E, Khoury B, Khoury SJ, Mokdad A, Meho LI, Okasha T, Reed GM, Sbaity E, Zeinoun P, Akl EA. Mental health research in the Arab region: challenges and call for action. Lancet Psychiatry. 2019 11; 6(11):961-966. PMID: 31327707.
    Citations: 6     Fields:    Translation:Humans
  11. Alroughani R, Akhtar S, Zeineddine M, El Kouzi Y, El Ayoubi NK, Ahmed SF, Behbehani R, Khoury SJ, Al-Hashel JY, Yamout BI. Risk of relapses during pregnancy among multiple sclerosis patients. Mult Scler Relat Disord. 2019 Sep; 34:9-13. PMID: 31202959.
    Citations: 2     Fields:    Translation:Humans
  12. Chehabeddine L, Al Saleh T, Baalbaki M, Saleh E, Khoury SJ, Hannoun S. Cumulative administrations of gadolinium-based contrast agents: risks of accumulation and toxicity of linear vs macrocyclic agents. Crit Rev Toxicol. 2019 03; 49(3):262-279. PMID: 30942117.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  13. Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E. Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance. J Immunol. 2019 03 01; 202(5):1373-1382. PMID: 30683697.
    Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
  14. Starossom SC, Campo Garcia J, Woelfle T, Romero-Suarez S, Olah M, Watanabe F, Cao L, Yeste A, Tukker JJ, Quintana FJ, Imitola J, Witzel F, Schmitz D, Morkel M, Paul F, Infante-Duarte C, Khoury SJ. Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation. Nat Commun. 2019 01 15; 10(1):217. PMID: 30644388.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  15. Kivisäkk P, Khoury SJ. Co-signaling Molecules in Neurological Diseases. Adv Exp Med Biol. 2019; 1189:233-265. PMID: 31758537.
    Citations:    Fields:    Translation:AnimalsCells
  16. Hannoun S, Issa R, El Ayoubi NK, Haddad R, Baalbaki M, Yamout BI, Khoury SJ, Hourani R. Gadoterate Meglumine Administration in Multiple Sclerosis has no Effect on the Dentate Nucleus and the Globus Pallidus Signal Intensities. Acad Radiol. 2019 10; 26(10):e284-e291. PMID: 30527456.
    Citations: 1     Fields:    Translation:Humans
  17. Yamout BI, El-Ayoubi NK, Nicolas J, El Kouzi Y, Khoury SJ, Zeineddine MM. Safety and Efficacy of Rituximab in Multiple Sclerosis: A Retrospective Observational Study. J Immunol Res. 2018; 2018:9084759. PMID: 30539030.
    Citations: 5     Fields:    Translation:Humans
  18. Said M, El Ayoubi NK, Hannoun S, Haddad R, Saba L, Jalkh Y, Yamout BI, Khoury SJ. The Bayesian risk estimate at onset (BREMSO) correlates with cognitive and physical disability in patients with early multiple sclerosis. Mult Scler Relat Disord. 2018 Nov; 26:96-102. PMID: 30243236.
    Citations: 1     Fields:    Translation:Humans
  19. Hannoun S, Baalbaki M, Haddad R, Saaybi S, El Ayoubi NK, Yamout BI, Khoury SJ, Hourani R. Gadolinium effect on thalamus and whole brain tissue segmentation. Neuroradiology. 2018 Nov; 60(11):1167-1173. PMID: 30128599.
    Citations: 1     Fields:    Translation:Humans
  20. Regev K, Healy BC, Paul A, Diaz-Cruz C, Mazzola MA, Raheja R, Glanz BI, Kivisäkk P, Chitnis T, Jagodic M, Piehl F, Olsson T, Khademi M, Hauser S, Oksenberg J, Khoury SJ, Weiner HL, Gandhi R. Identification of MS-specific serum miRNAs in an international multicenter study. Neurol Neuroimmunol Neuroinflamm. 2018 Sep; 5(5):e491. PMID: 30175165.
    Citations: 10     Fields:    
  21. Yamout BI, Sahraian MA, Ayoubi NE, Tamim H, Nicolas J, Khoury SJ, Zeineddine MM. Efficacy and safety of natalizumab extended interval dosing. Mult Scler Relat Disord. 2018 Aug; 24:113-116. PMID: 29982107.
    Citations: 7     Fields:    Translation:Humans
  22. Longbrake EE, Kantor D, Pawate S, Bradshaw MJ, von Geldern G, Chahin S, Cross AH, Parks BJ, Rice M, Khoury SJ, Yamout B, Zeineddine M, Russell-Giller S, Caminero-Rodriguez A, Edwards K, Lathi E, VanderKodde D, Meador W, Berkovich R, Ge L, Bacon TE, Kister I. Effectiveness of alternative dose fingolimod for multiple sclerosis. Neurol Clin Pract. 2018 Apr; 8(2):102-107. PMID: 29708225.
    Citations: 3     
  23. Buttrick TS, Wang W, Yung C, Trieu KG, Patel K, Khoury SJ, Ai X, Elyaman W. Foxo1 Promotes Th9 Cell Differentiation and Airway Allergy. Sci Rep. 2018 01 16; 8(1):818. PMID: 29339772.
    Citations: 5     Fields:    Translation:AnimalsCells
  24. Yamout BI, Khoury SJ, Ayyoubi N, Doumiati H, Fakhreddine M, Ahmed SF, Tamim H, Al-Hashel JY, Behbehani R, Alroughani R. Alternative diagnoses in patients referred to specialized centers for suspected MS. Mult Scler Relat Disord. 2017 Nov; 18:85-89. PMID: 29141828.
    Citations: 3     Fields:    Translation:Humans
  25. Buttrick T, Khoury SJ, Elyaman W. Opposite functions of STAT3 and Smad3 in regulating Tiam1 expression in Th17 cells. Small GTPases. 2020 01; 11(1):62-68. PMID: 28609201.
    Citations: 1     Fields:    
  26. Bove R, Chitnis T, Cree BA, Tintoré M, Naegelin Y, Uitdehaag BM, Kappos L, Khoury SJ, Montalban X, Hauser SL, Weiner HL. SUMMIT (Serially Unified Multicenter Multiple Sclerosis Investigation): creating a repository of deeply phenotyped contemporary multiple sclerosis cohorts. Mult Scler. 2018 10; 24(11):1485-1498. PMID: 28847219.
    Citations: 5     Fields:    Translation:Humans
  27. Yamout BI, Said M, Hannoun S, Zeineddine M, Massouh J, Khoury SJ. Rebound syndrome after teriflunomide cessation in a patient with multiple sclerosis. J Neurol Sci. 2017 Sep 15; 380:79-81. PMID: 28870594.
    Citations:    Fields:    Translation:Humans
  28. Mrad MF, El Ayoubi NK, Esmerian MO, Kazan JM, Khoury SJ. Effect of vitamin D replacement on immunological biomarkers in patients with multiple sclerosis. Clin Immunol. 2017 08; 181:9-15. PMID: 28536054.
    Citations: 2     Fields:    Translation:HumansCells
  29. Darwish H, Haddad R, Osman S, Ghassan S, Yamout B, Tamim H, Khoury S. Effect of Vitamin D Replacement on Cognition in Multiple Sclerosis Patients. Sci Rep. 2017 04 04; 7:45926. PMID: 28374837.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  30. El Ayoubi NK, Khoury SJ. Blood Biomarkers as Outcome Measures in Inflammatory Neurologic Diseases. Neurotherapeutics. 2017 01; 14(1):135-147. PMID: 27757816.
    Citations: 3     Fields:    Translation:Humans
  31. Azcutia V, Bassil R, Herter JM, Engelbertsen D, Newton G, Autio A, Mayadas T, Lichtman AH, Khoury SJ, Parkos CA, Elyaman W, Luscinskas FW. Defects in CD4+ T cell LFA-1 integrin-dependent adhesion and proliferation protect Cd47-/- mice from EAE. J Leukoc Biol. 2017 02; 101(2):493-505. PMID: 27965383.
    Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  32. Elyaman W, Khoury SJ. Th9 cells in the pathogenesis of EAE and multiple sclerosis. Semin Immunopathol. 2017 01; 39(1):79-87. PMID: 27844107.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  33. Khoury S, Graczyk T, Burnham G, Jurdi M, Goldman L. Drinking water system treatment and contamination in Shatila Refugee Camp in Beirut, Lebanon. East Mediterr Health J. 2016 Nov 02; 22(8):568-578. PMID: 27834438.
    Citations:    Fields:    Translation:HumansPHPublic Health
  34. Kurdi AT, Bassil R, Olah M, Wu C, Xiao S, Taga M, Frangieh M, Buttrick T, Orent W, Bradshaw EM, Khoury SJ, Elyaman W. Tiam1/Rac1 complex controls Il17a transcription and autoimmunity. Nat Commun. 2016 10 11; 7:13048. PMID: 27725632.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  35. El Ayoubi NK, Ghassan S, Said M, Allam J, Darwish H, Khoury SJ. Retinal measures correlate with cognitive and physical disability in early multiple sclerosis. J Neurol. 2016 Nov; 263(11):2287-2295. PMID: 27544501.
    Citations: 8     Fields:    Translation:Humans
  36. Khoury SJ, Rochon J, Ding L, Byron M, Ryker K, Tosta P, Gao W, Freedman MS, Arnold DL, Sayre PH, Smilek DE. ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis. Mult Scler. 2017 Apr; 23(5):686-695. PMID: 27481207.
    Citations: 9     Fields:    Translation:Humans
  37. Bou Fakhredin R, Saade C, Kerek R, El-Jamal L, Khoury SJ, El-Merhi F. Imaging in multiple sclerosis: A new spin on lesions. J Med Imaging Radiat Oncol. 2016 Oct; 60(5):577-586. PMID: 27464473.
    Citations: 2     Fields:    Translation:Humans
  38. Yamout BI, Abou Zeid N, Taha AJ, Zeineddine MM, Khoury SJ. Three cases of herpes zoster radiculitis in MS patients treated with natalizumab. Mult Scler Relat Disord. 2016 Sep; 9:122-4. PMID: 27645358.
    Citations:    Fields:    Translation:Humans
  39. Dagher MM, Atieh JA, Soubra MK, Khoury SJ, Tamim H, Kaafarani BR. Medical Research Volunteer Program (MRVP): innovative program promoting undergraduate research in the medical field. BMC Med Educ. 2016 Jun 06; 16:160. PMID: 27267261.
    Citations: 3     Fields:    Translation:Humans
  40. Fawaz L, Mrad MF, Kazan JM, Sayegh S, Akika R, Khoury SJ. Comparative effect of 25(OH)D3 and 1,25(OH)2D3 on Th17 cell differentiation. Clin Immunol. 2016 May; 166-167:59-71. PMID: 27041081.
    Citations: 12     Fields:    Translation:HumansCells
  41. Alroughani R, Akhtar S, Ahmed SF, Khoury SJ, Al-Hashel JY, Sahraian MA, Al Jumah M, Zeineddine M, Farhat S, Doumiati H, Yamout BI. JC virus seroprevalence and seroconversion in multiple sclerosis cohort: A Middle-Eastern study. J Neurol Sci. 2016 Jan 15; 360:61-5. PMID: 26723975.
    Citations: 8     Fields:    Translation:HumansCells
  42. Orent W, Mchenry AR, Rao DA, White C, Klein HU, Bassil R, Srivastava G, Replogle JM, Raj T, Frangieh M, Cimpean M, Cuerdon N, Chibnik L, Khoury SJ, Karlson EW, Brenner MB, De Jager P, Bradshaw EM, Elyaman W. Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells. Hum Mol Genet. 2016 Jan 15; 25(2):404-17. PMID: 26604133.
    Citations: 3     Fields:    Translation:HumansCells
  43. Yamout BI, Zeineddine MM, Tamim H, Khoury SJ. Safety and efficacy of fingolimod in clinical practice: The experience of an academic center in the Middle East. J Neuroimmunol. 2015 Dec 15; 289:93-7. PMID: 26616877.
    Citations: 7     Fields:    Translation:Humans
  44. Darwish H, Zeinoun P, Ghusn H, Khoury B, Tamim H, Khoury SJ. Serum 25-hydroxyvitamin D predicts cognitive performance in adults. Neuropsychiatr Dis Treat. 2015; 11:2217-23. PMID: 26346368.
    Citations: 8     
  45. Merzaban JS, Imitola J, Starossom SC, Zhu B, Wang Y, Lee J, Ali AJ, Olah M, Abuelela AF, Khoury SJ, Sackstein R. Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosis. Glycobiology. 2015 Dec; 25(12):1392-409. PMID: 26153105.
    Citations: 19     Fields:    Translation:AnimalsCells
  46. Yamout B, Alroughani R, Al-Jumah M, Goueider R, Dahdaleh M, Inshasi J, Hashem S, Alsharoqi I, Sahraian M, Khoury S, Alkawi Z, Koussa S, Zakaria M, Al Khaburi J, Alsaadi T, Bohlega S. Consensus recommendations for the diagnosis and treatment of multiple sclerosis: the Middle East North Africa Committee for Treatment and Research In Multiple Sclerosis (MENACTRIMS). Curr Med Res Opin. 2015; 31(7):1349-61. PMID: 25946578.
    Citations: 4     Fields:    Translation:Humans
  47. Yamout BI, Zeineddine MM, Sawaya RA, Khoury SJ. Safety and efficacy of reduced fingolimod dosage treatment. J Neuroimmunol. 2015 Aug 15; 285:13-5. PMID: 26198913.
    Citations: 5     Fields:    Translation:HumansCells
  48. Mouhieddine TH, Darwish H, Fawaz L, Yamout B, Tamim H, Khoury SJ. Risk factors for multiple sclerosis and associations with anti-EBV antibody titers. Clin Immunol. 2015 May; 158(1):59-66. PMID: 25805657.
    Citations: 5     Fields:    Translation:HumansCells
  49. Kivisäkk P, Francois K, Mbianda J, Gandhi R, Weiner HL, Khoury SJ. Effect of natalizumab treatment on circulating plasmacytoid dendritic cells: a cross-sectional observational study in patients with multiple sclerosis. PLoS One. 2014; 9(7):e103716. PMID: 25075741.
    Citations: 3     Fields:    Translation:HumansCells
  50. Bassil R, Orent W, Olah M, Kurdi AT, Frangieh M, Buttrick T, Khoury SJ, Elyaman W. BCL6 controls Th9 cell development by repressing Il9 transcription. J Immunol. 2014 Jul 01; 193(1):198-207. PMID: 24879792.
    Citations: 22     Fields:    Translation:AnimalsCells
  51. Messina S, Vargas-Lowy D, Musallam A, Healy BC, Kivisakk P, Gandhi R, Bove R, Gholipour T, Khoury S, Weiner HL, Chitnis T. Increased leptin and A-FABP levels in relapsing and progressive forms of MS. BMC Neurol. 2013 Nov 11; 13:172. PMID: 24215402.
    Citations: 4     Fields:    Translation:Humans
  52. Ottoboni L, Frohlich IY, Lee M, Healy BC, Keenan BT, Xia Z, Chitnis T, Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, De Jager PL. Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus. Neurology. 2013 Nov 26; 81(22):1891-9. PMID: 24174586.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  53. Yamout B, El-Salem K, Gebeily S, Khoury S, Abu Zeid N, Hamoulila K, Alhalabi MS, Hasan ZN, Al Hamadani H, Hamoodi H, Al Omar A, Dahdaleh M. Multiple sclerosis in the Levant: a regional consensus statement. Int J Neurosci. 2014 May; 124(5):377-82. PMID: 23927564.
    Citations: 1     Fields:    Translation:Humans
  54. Kivisäkk P, Healy BC, Francois K, Gandhi R, Gholipour T, Egorova S, Sevdalinova V, Quintana F, Chitnis T, Weiner HL, Khoury SJ. Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development. Mult Scler. 2014 Apr; 20(4):438-44. PMID: 24005026.
    Citations: 12     Fields:    Translation:Humans
  55. Zhu B, Buttrick T, Bassil R, Zhu C, Olah M, Wu C, Xiao S, Orent W, Elyaman W, Khoury SJ. IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing Aldh1a2. J Immunol. 2013 Sep 15; 191(6):3139-51. PMID: 23960232.
    Citations: 21     Fields:    Translation:AnimalsCells
  56. Chitnis T, Khoury SJ. Sex influences in autoimmune disease. Clin Immunol. 2013 Nov; 149(2):169. PMID: 24012474.
    Citations:    Fields:    Translation:Humans
  57. Gandhi R, Healy B, Gholipour T, Egorova S, Musallam A, Hussain MS, Nejad P, Patel B, Hei H, Khoury S, Quintana F, Kivisakk P, Chitnis T, Weiner HL. Circulating microRNAs as biomarkers for disease staging in multiple sclerosis. Ann Neurol. 2013 Jun; 73(6):729-40. PMID: 23494648.
    Citations: 78     Fields:    Translation:Humans
  58. Bove R, Musallam A, Healy BC, Houtchens M, Glanz BI, Khoury S, Guttmann CR, De Jager PL, Chitnis T. No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50. BMC Neurol. 2013 Jul 03; 13:73. PMID: 23822612.
    Citations: 10     Fields:    Translation:Humans
  59. Yamout B, Alroughani R, Al-Jumah M, Khoury S, Abouzeid N, Dahdaleh M, Alsharoqi I, Inshasi J, Hashem S, Zakaria M, ElKallab K, Alsaadi T, Tawfeek T, Bohlega S. Consensus guidelines for the diagnosis and treatment of multiple sclerosis. Curr Med Res Opin. 2013 Jun; 29(6):611-21. PMID: 23514115.
    Citations: 4     Fields:    Translation:Humans
  60. Abrams P, Chapple C, Khoury S, Roehrborn C, de la Rosette J. Evaluation and treatment of lower urinary tract symptoms in older men. J Urol. 2013 Jan; 189(1 Suppl):S93-S101. PMID: 23234640.
    Citations: 25     Fields:    Translation:Humans
  61. Vargas-Lowy D, Kivisäkk P, Gandhi R, Raddassi K, Soltany P, Gorman MP, Khoury SJ, Chitnis T. Increased Th17 response to myelin peptides in pediatric MS. Clin Immunol. 2013 Mar; 146(3):176-84. PMID: 23352968.
    Citations: 7     Fields:    Translation:HumansCells
  62. Ottoboni L, Keenan BT, Tamayo P, Kuchroo M, Mesirov JP, Buckle GJ, Khoury SJ, Hafler DA, Weiner HL, De Jager PL. An RNA profile identifies two subsets of multiple sclerosis patients differing in disease activity. Sci Transl Med. 2012 Sep 26; 4(153):153ra131. PMID: 23019656.
    Citations: 25     Fields:    Translation:HumansCells
  63. Cousens LP, Najafian N, Mingozzi F, Elyaman W, Mazer B, Moise L, Messitt TJ, Su Y, Sayegh M, High K, Khoury SJ, Scott DW, De Groot AS. In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity. J Clin Immunol. 2013 Jan; 33 Suppl 1:S43-9. PMID: 22941509.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  64. Starossom SC, Mascanfroni ID, Imitola J, Cao L, Raddassi K, Hernandez SF, Bassil R, Croci DO, Cerliani JP, Delacour D, Wang Y, Elyaman W, Khoury SJ, Rabinovich GA. Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration. Immunity. 2012 Aug 24; 37(2):249-63. PMID: 22884314.
    Citations: 114     Fields:    Translation:HumansAnimalsCells
  65. Purwar R, Schlapbach C, Xiao S, Kang HS, Elyaman W, Jiang X, Jetten AM, Khoury SJ, Fuhlbrigge RC, Kuchroo VK, Clark RA, Kupper TS. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat Med. 2012 Aug; 18(8):1248-53. PMID: 22772464.
    Citations: 141     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  66. Elyaman W, Bassil R, Bradshaw EM, Orent W, Lahoud Y, Zhu B, Radtke F, Yagita H, Khoury SJ. Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells. Immunity. 2012 Apr 20; 36(4):623-34. PMID: 22503540.
    Citations: 54     Fields:    Translation:AnimalsCells
  67. Ceccarelli A, Jackson JS, Tauhid S, Arora A, Gorky J, Dell'Oglio E, Bakshi A, Chitnis T, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R, Neema M. The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis. AJNR Am J Neuroradiol. 2012 Sep; 33(8):1579-85. PMID: 22460341.
    Citations: 33     Fields:    Translation:Humans
  68. Okada H, Khoury SJ. Type17 T-cells in central nervous system autoimmunity and tumors. J Clin Immunol. 2012 Aug; 32(4):802-8. PMID: 22454247.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  69. Zhu B, Trikudanathan S, Zozulya AL, Sandoval-Garcia C, Kennedy JK, Atochina O, Norberg T, Castagner B, Seeberger P, Fabry Z, Harn D, Khoury SJ, Guleria I. Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis. Clin Immunol. 2012 Mar; 142(3):351-61. PMID: 22264636.
    Citations: 17     Fields:    Translation:AnimalsCells
  70. Moodie J, Healy BC, Buckle GJ, Gauthier SA, Glanz BI, Arora A, Ceccarelli A, Tauhid S, Han XM, Venkataraman A, Chitnis T, Khoury SJ, Guttmann CR, Weiner HL, Neema M, Bakshi R. Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study. J Neurol Sci. 2012 Apr 15; 315(1-2):49-54. PMID: 22209496.
    Citations: 9     Fields:    Translation:Humans
  71. Comabella M, Khoury SJ. Therapeutic strategies in multiple sclerosis. Clin Immunol. 2012 Jan; 142(1):1. PMID: 22155340.
    Citations:    Fields:    Translation:Humans
  72. Elyaman W, Khoury SJ, Scott DW, De Groot AS. Potential application of tregitopes as immunomodulating agents in multiple sclerosis. Neurol Res Int. 2011; 2011:256460. PMID: 21941651.
    Citations: 12     
  73. Zhu B, Kennedy JK, Wang Y, Sandoval-Garcia C, Cao L, Xiao S, Wu C, Elyaman W, Khoury SJ. Plasticity of Ly-6C(hi) myeloid cells in T cell regulation. J Immunol. 2011 Sep 01; 187(5):2418-32. PMID: 21824867.
    Citations: 27     Fields:    Translation:AnimalsCells
  74. Bassil R, Zhu B, Lahoud Y, Riella LV, Yagita H, Elyaman W, Khoury SJ. Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development. J Immunol. 2011 Sep 01; 187(5):2322-8. PMID: 21813770.
    Citations: 29     Fields:    Translation:AnimalsCells
  75. Stankiewicz JM, Glanz BI, Healy BC, Arora A, Neema M, Benedict RH, Guss ZD, Tauhid S, Buckle GJ, Houtchens MK, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R. Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis. J Neuroimaging. 2011 Apr; 21(2):e50-6. PMID: 19888926.
    Citations: 45     Fields:    Translation:Humans
  76. Holland CM, Charil A, Csapo I, Liptak Z, Ichise M, Khoury SJ, Bakshi R, Weiner HL, Guttmann CR. The relationship between normal cerebral perfusion patterns and white matter lesion distribution in 1,249 patients with multiple sclerosis. J Neuroimaging. 2012 Apr; 22(2):129-36. PMID: 21447022.
    Citations: 23     Fields:    Translation:HumansCells
  77. Khoury SJ. Th17 and Treg balance in systemic sclerosis. Clin Immunol. 2011 Jun; 139(3):231-2. PMID: 21482482.
    Citations: 8     Fields:    Translation:HumansCells
  78. Liguori M, Meier DS, Hildenbrand P, Healy BC, Chitnis T, Baruch NF, Khoury SJ, Weiner HL, Bakshi R, Barkhof F, Guttmann CR. One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2011 Oct; 82(10):1125-31. PMID: 21429902.
    Citations: 3     Fields:    Translation:Humans
  79. Comabella M, Khoury SJ. Immunopathogenesis of multiple sclerosis. Clin Immunol. 2012 Jan; 142(1):2-8. PMID: 21458377.
    Citations: 40     Fields:    Translation:Humans
  80. Rasmussen S, Imitola J, Ayuso-Sacido A, Wang Y, Starossom SC, Kivisäkk P, Zhu B, Meyer M, Bronson RT, Garcia-Verdugo JM, Khoury SJ. Reversible neural stem cell niche dysfunction in a model of multiple sclerosis. Ann Neurol. 2011 May; 69(5):878-91. PMID: 21391234.
    Citations: 36     Fields:    Translation:AnimalsCellsPHPublic Health
  81. Imitola J, Côté D, Rasmussen S, Xie XS, Liu Y, Chitnis T, Sidman RL, Lin CP, Khoury SJ. Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice. J Biomed Opt. 2011 Feb; 16(2):021109. PMID: 21361672.
    Citations: 23     Fields:    Translation:AnimalsCells
  82. Liguori M, Healy BC, Glanz BI, Khoury SJ, Moscufo N, Weiner HL, De Jager PL, Guttmann CR. HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study. Genes Immun. 2011 Apr; 12(3):183-90. PMID: 21179117.
    Citations: 3     Fields:    Translation:Humans
  83. Khoury S, Bakshi R. Cerebral pseudoatrophy or real atrophy after therapy in multiple sclerosis. Ann Neurol. 2010 Dec; 68(6):778-9. PMID: 21194148.
    Citations: 9     Fields:    Translation:Humans
  84. Xia Z, Chibnik LB, Glanz BI, Liguori M, Shulman JM, Tran D, Khoury SJ, Chitnis T, Holyoak T, Weiner HL, Guttmann CR, De Jager PL. A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis. PLoS One. 2010 Nov 30; 5(11):e14169. PMID: 21152065.
    Citations: 11     Fields:    Translation:Humans
  85. Gross R, Healy BC, Cepok S, Chitnis T, Khoury SJ, Hemmer B, Weiner HL, Hafler DA, De Jager PL. Population structure and HLA DRB1 1501 in the response of subjects with multiple sclerosis to first-line treatments. J Neuroimmunol. 2011 Apr; 233(1-2):168-74. PMID: 21115201.
    Citations: 10     Fields:    Translation:Humans
  86. Starossom SC, Imitola J, Wang Y, Cao L, Khoury SJ. Subventricular zone microglia transcriptional networks. Brain Behav Immun. 2011 Jul; 25(5):991-9. PMID: 21074605.
    Citations: 5     Fields:    Translation:AnimalsCells
  87. Khoury SJ, Healy BC, Kivisäkk P, Viglietta V, Egorova S, Guttmann CR, Wedgwood JF, Hafler DA, Weiner HL, Buckle G, Cook S, Reddy S. A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis. Arch Neurol. 2010 Sep; 67(9):1055-61. PMID: 20837847.
    Citations: 13     Fields:    Translation:Humans
  88. Healy BC, Liguori M, Tran D, Chitnis T, Glanz B, Wolfish C, Gauthier S, Buckle G, Houtchens M, Stazzone L, Khoury S, Hartzmann R, Fernandez-Vina M, Hafler DA, Weiner HL, Guttmann CR, De Jager PL. HLA B*44: protective effects in MS susceptibility and MRI outcome measures. Neurology. 2010 Aug 17; 75(7):634-40. PMID: 20713950.
    Citations: 23     Fields:    Translation:Humans
  89. Beriou G, Bradshaw EM, Lozano E, Costantino CM, Hastings WD, Orban T, Elyaman W, Khoury SJ, Kuchroo VK, Baecher-Allan C, Hafler DA. TGF-beta induces IL-9 production from human Th17 cells. J Immunol. 2010 Jul 01; 185(1):46-54. PMID: 20498357.
    Citations: 60     Fields:    Translation:HumansCells
  90. Liu Y, Bando Y, Vargas-Lowy D, Elyaman W, Khoury SJ, Huang T, Reif K, Chitnis T. CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis. J Neurosci. 2010 Feb 10; 30(6):2025-38. PMID: 20147531.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  91. Abrams P, Andersson KE, Birder L, Brubaker L, Cardozo L, Chapple C, Cottenden A, Davila W, de Ridder D, Dmochowski R, Drake M, Dubeau C, Fry C, Hanno P, Smith JH, Herschorn S, Hosker G, Kelleher C, Koelbl H, Khoury S, Madoff R, Milsom I, Moore K, Newman D, Nitti V, Norton C, Nygaard I, Payne C, Smith A, Staskin D, Tekgul S, Thuroff J, Tubaro A, Vodusek D, Wein A, Wyndaele JJ. Fourth International Consultation on Incontinence Recommendations of the International Scientific Committee: Evaluation and treatment of urinary incontinence, pelvic organ prolapse, and fecal incontinence. Neurourol Urodyn. 2010; 29(1):213-40. PMID: 20025020.
    Citations: 228     Fields:    Translation:Humans
  92. Ilan Y, Zigmond E, Lalazar G, Dembinsky A, Ben Ya'acov A, Hemed N, Kasis I, Axelrod E, Zolotarov L, Klein A, El Haj M, Gandhi R, Baecher-Allan C, Wu H, Murugaiyan G, Kivisakk P, Farez MF, Quintana FJ, Khoury SJ, Weiner HL. Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells. J Clin Immunol. 2010 Jan; 30(1):167-77. PMID: 19756989.
    Citations: 28     Fields:    Translation:HumansCellsCTClinical Trials
  93. McLaughlin KA, Chitnis T, Newcombe J, Franz B, Kennedy J, McArdel S, Kuhle J, Kappos L, Rostasy K, Pohl D, Gagne D, Ness JM, Tenembaum S, O'Connor KC, Viglietta V, Wong SJ, Tavakoli NP, de Seze J, Idrissova Z, Khoury SJ, Bar-Or A, Hafler DA, Banwell B, Wucherpfennig KW. Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis. J Immunol. 2009 Sep 15; 183(6):4067-76. PMID: 19687098.
    Citations: 70     Fields:    Translation:HumansCells
  94. Healy BC, Ali EN, Guttmann CR, Chitnis T, Glanz BI, Buckle G, Houtchens M, Stazzone L, Moodie J, Berger AM, Duan Y, Bakshi R, Khoury S, Weiner H, Ascherio A. Smoking and disease progression in multiple sclerosis. Arch Neurol. 2009 Jul; 66(7):858-64. PMID: 19597087.
    Citations: 47     Fields:    Translation:Humans
  95. Kivisäkk P, Healy BC, Viglietta V, Quintana FJ, Hootstein MA, Weiner HL, Khoury SJ. Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells. Neurology. 2009 Jun 02; 72(22):1922-30. PMID: 19487650.
    Citations: 55     Fields:    Translation:HumansCells
  96. Elyaman W, Bradshaw EM, Uyttenhove C, Dardalhon V, Awasthi A, Imitola J, Bettelli E, Oukka M, van Snick J, Renauld JC, Kuchroo VK, Khoury SJ. IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells. Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):12885-90. PMID: 19433802.
    Citations: 168     Fields:    Translation:AnimalsCells
  97. Gauthier SA, Glanz BI, Mandel M, Tsagkaropoulos A, Neema M, Stankiewicz J, Arora A, Duan Y, Liptak Z, Egorova S, Buckle GJ, Bakshi R, Guttmann CR, Khoury SJ, Weiner HL. Incidence and factors associated with treatment failure in the CLIMB multiple sclerosis cohort study. J Neurol Sci. 2009 Sep 15; 284(1-2):116-9. PMID: 19428028.
    Citations: 6     Fields:    Translation:Humans
  98. Kivisäkk P, Imitola J, Rasmussen S, Elyaman W, Zhu B, Ransohoff RM, Khoury SJ. Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis. Ann Neurol. 2009 Apr; 65(4):457-69. PMID: 18496841.
    Citations: 111     Fields:    Translation:AnimalsCells
  99. Gauthier SA, Berger AM, Liptak Z, Duan Y, Egorova S, Buckle GJ,