Harvard Catalyst Profiles

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Samia Joseph Khoury, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R13NS080494 (KHOURY, SAMIA J.) Sep 1, 2012 - Aug 31, 2013
    NIH/NINDS
    11th International Congress of Neuroimmunology
    Role: Principal Investigator
  2. R56AI093838 (KHOURY, SAMIA J.) Aug 15, 2012 - Jul 31, 2014
    NIH/NIAID
    Neural Stem Cells and Regulatory T Cells
    Role: Principal Investigator
  3. R01AI067472 (KHOURY, SAMIA J.) Apr 1, 2008 - Sep 30, 2013
    NIH/NIAID
    MEMORY T CELLS IN EAE
    Role: Principal Investigator
  4. R01AI071448 (KHOURY, SAMIA J.) Apr 1, 2007 - Mar 31, 2011
    NIH/NIAID
    Impact of IFN-gamma on Neural Stem Cell Repair Potential in EAE
    Role: Principal Investigator
  5. R56AI058680 (KHOURY, SAMIA J.) Dec 1, 2003 - May 31, 2011
    NIH/NIAID
    Role and mechanism of negative costimulatory pathways in EAE
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chehabeddine L, Al Saleh T, Baalbaki M, Saleh E, Khoury SJ, Hannoun S. Cumulative administrations of gadolinium-based contrast agents: risks of accumulation and toxicity of linear vs macrocyclic agents. Crit Rev Toxicol. 2019 Apr 03; 1-18. PMID: 30942117.
    Citations:    
  2. Glatigny S, Höllbacher B, Motley SJ, Tan C, Hundhausen C, Buckner JH, Smilek D, Khoury SJ, Ding L, Qin T, Pardo J, Nepom GT, Turka LA, Harris KM, Campbell DJ, Bettelli E. Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance. J Immunol. 2019 Mar 01; 202(5):1373-1382. PMID: 30683697.
    Citations:    Fields:    
  3. Starossom SC, Campo Garcia J, Woelfle T, Romero-Suarez S, Olah M, Watanabe F, Cao L, Yeste A, Tukker JJ, Quintana FJ, Imitola J, Witzel F, Schmitz D, Morkel M, Paul F, Infante-Duarte C, Khoury SJ. Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation. Nat Commun. 2019 01 15; 10(1):217. PMID: 30644388.
    Citations:    Fields:    
  4. Hannoun S, Issa R, El Ayoubi NK, Haddad R, Baalbaki M, Yamout BI, Khoury SJ, Hourani R. Gadoterate Meglumine Administration in Multiple Sclerosis has no Effect on the Dentate Nucleus and the Globus Pallidus Signal Intensities. Acad Radiol. 2018 Dec 05. PMID: 30527456.
    Citations:    Fields:    
  5. Yamout BI, El-Ayoubi NK, Nicolas J, El Kouzi Y, Khoury SJ, Zeineddine MM. Safety and Efficacy of Rituximab in Multiple Sclerosis: A Retrospective Observational Study. J Immunol Res. 2018; 2018:9084759. PMID: 30539030.
    Citations:    Fields:    Translation:Humans
  6. Said M, El Ayoubi NK, Hannoun S, Haddad R, Saba L, Jalkh Y, Yamout BI, Khoury SJ. The Bayesian risk estimate at onset (BREMSO) correlates with cognitive and physical disability in patients with early multiple sclerosis. Mult Scler Relat Disord. 2018 Nov; 26:96-102. PMID: 30243236.
    Citations:    Fields:    
  7. Hannoun S, Baalbaki M, Haddad R, Saaybi S, El Ayoubi NK, Yamout BI, Khoury SJ, Hourani R. Gadolinium effect on thalamus and whole brain tissue segmentation. Neuroradiology. 2018 Nov; 60(11):1167-1173. PMID: 30128599.
    Citations:    Fields:    Translation:Humans
  8. Regev K, Healy BC, Paul A, Diaz-Cruz C, Mazzola MA, Raheja R, Glanz BI, Kivisäkk P, Chitnis T, Jagodic M, Piehl F, Olsson T, Khademi M, Hauser S, Oksenberg J, Khoury SJ, Weiner HL, Gandhi R. Identification of MS-specific serum miRNAs in an international multicenter study. Neurol Neuroimmunol Neuroinflamm. 2018 Sep; 5(5):e491. PMID: 30175165.
    Citations:    
  9. Yamout BI, Sahraian MA, Ayoubi NE, Tamim H, Nicolas J, Khoury SJ, Zeineddine MM. Efficacy and safety of natalizumab extended interval dosing. Mult Scler Relat Disord. 2018 Aug; 24:113-116. PMID: 29982107.
    Citations:    Fields:    Translation:Humans
  10. Longbrake EE, Kantor D, Pawate S, Bradshaw MJ, von Geldern G, Chahin S, Cross AH, Parks BJ, Rice M, Khoury SJ, Yamout B, Zeineddine M, Russell-Giller S, Caminero-Rodriguez A, Edwards K, Lathi E, VanderKodde D, Meador W, Berkovich R, Ge L, Bacon TE, Kister I. Effectiveness of alternative dose fingolimod for multiple sclerosis. Neurol Clin Pract. 2018 Apr; 8(2):102-107. PMID: 29708225.
    Citations:    
  11. Buttrick TS, Wang W, Yung C, Trieu KG, Patel K, Khoury SJ, Ai X, Elyaman W. Foxo1 Promotes Th9 Cell Differentiation and Airway Allergy. Sci Rep. 2018 01 16; 8(1):818. PMID: 29339772.
    Citations: 1     Fields:    Translation:AnimalsCells
  12. Yamout BI, Khoury SJ, Ayyoubi N, Doumiati H, Fakhreddine M, Ahmed SF, Tamim H, Al-Hashel JY, Behbehani R, Alroughani R. Alternative diagnoses in patients referred to specialized centers for suspected MS. Mult Scler Relat Disord. 2017 Nov; 18:85-89. PMID: 29141828.
    Citations:    Fields:    Translation:Humans
  13. Bove R, Chitnis T, Cree BA, Tintoré M, Naegelin Y, Uitdehaag BM, Kappos L, Khoury SJ, Montalban X, Hauser SL, Weiner HL. SUMMIT (Serially Unified Multicenter Multiple Sclerosis Investigation): creating a repository of deeply phenotyped contemporary multiple sclerosis cohorts. Mult Scler. 2018 10; 24(11):1485-1498. PMID: 28847219.
    Citations: 1     Fields:    
  14. Yamout BI, Said M, Hannoun S, Zeineddine M, Massouh J, Khoury SJ. Rebound syndrome after teriflunomide cessation in a patient with multiple sclerosis. J Neurol Sci. 2017 Sep 15; 380:79-81. PMID: 28870594.
    Citations:    Fields:    Translation:Humans
  15. Buttrick T, Khoury SJ, Elyaman W. Opposite functions of STAT3 and Smad3 in regulating Tiam1 expression in Th17 cells. Small GTPases. 2017 Jun 13; 1-7. PMID: 28609201.
    Citations:    Fields:    
  16. Mrad MF, El Ayoubi NK, Esmerian MO, Kazan JM, Khoury SJ. Effect of vitamin D replacement on immunological biomarkers in patients with multiple sclerosis. Clin Immunol. 2017 08; 181:9-15. PMID: 28536054.
    Citations:    Fields:    Translation:HumansCells
  17. Darwish H, Haddad R, Osman S, Ghassan S, Yamout B, Tamim H, Khoury S. Effect of Vitamin D Replacement on Cognition in Multiple Sclerosis Patients. Sci Rep. 2017 04 04; 7:45926. PMID: 28374837.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  18. El Ayoubi NK, Khoury SJ. Blood Biomarkers as Outcome Measures in Inflammatory Neurologic Diseases. Neurotherapeutics. 2017 01; 14(1):135-147. PMID: 27757816.
    Citations: 1     Fields:    Translation:Humans
  19. Azcutia V, Bassil R, Herter JM, Engelbertsen D, Newton G, Autio A, Mayadas T, Lichtman AH, Khoury SJ, Parkos CA, Elyaman W, Luscinskas FW. Defects in CD4+ T cell LFA-1 integrin-dependent adhesion and proliferation protect Cd47-/- mice from EAE. J Leukoc Biol. 2017 02; 101(2):493-505. PMID: 27965383.
    Citations:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
  20. Elyaman W, Khoury SJ. Th9 cells in the pathogenesis of EAE and multiple sclerosis. Semin Immunopathol. 2017 01; 39(1):79-87. PMID: 27844107.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  21. Khoury S, Graczyk T, Burnham G, Jurdi M, Goldman L. Drinking water system treatment and contamination in Shatila Refugee Camp in Beirut, Lebanon. East Mediterr Health J. 2016 Nov 02; 22(8):568-578. PMID: 27834438.
    Citations:    Fields:    Translation:HumansPHPublic Health
  22. Kurdi AT, Bassil R, Olah M, Wu C, Xiao S, Taga M, Frangieh M, Buttrick T, Orent W, Bradshaw EM, Khoury SJ, Elyaman W. Tiam1/Rac1 complex controls Il17a transcription and autoimmunity. Nat Commun. 2016 10 11; 7:13048. PMID: 27725632.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  23. El Ayoubi NK, Ghassan S, Said M, Allam J, Darwish H, Khoury SJ. Retinal measures correlate with cognitive and physical disability in early multiple sclerosis. J Neurol. 2016 Nov; 263(11):2287-2295. PMID: 27544501.
    Citations: 3     Fields:    Translation:Humans
  24. Khoury SJ, Rochon J, Ding L, Byron M, Ryker K, Tosta P, Gao W, Freedman MS, Arnold DL, Sayre PH, Smilek DE. ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis. Mult Scler. 2017 Apr; 23(5):686-695. PMID: 27481207.
    Citations: 4     Fields:    Translation:Humans
  25. Bou Fakhredin R, Saade C, Kerek R, El-Jamal L, Khoury SJ, El-Merhi F. Imaging in multiple sclerosis: A new spin on lesions. J Med Imaging Radiat Oncol. 2016 Oct; 60(5):577-586. PMID: 27464473.
    Citations:    Fields:    Translation:Humans
  26. Yamout BI, Abou Zeid N, Taha AJ, Zeineddine MM, Khoury SJ. Three cases of herpes zoster radiculitis in MS patients treated with natalizumab. Mult Scler Relat Disord. 2016 Sep; 9:122-4. PMID: 27645358.
    Citations:    Fields:    Translation:Humans
  27. Dagher MM, Atieh JA, Soubra MK, Khoury SJ, Tamim H, Kaafarani BR. Medical Research Volunteer Program (MRVP): innovative program promoting undergraduate research in the medical field. BMC Med Educ. 2016 Jun 06; 16:160. PMID: 27267261.
    Citations: 1     Fields:    Translation:Humans
  28. Fawaz L, Mrad MF, Kazan JM, Sayegh S, Akika R, Khoury SJ. Comparative effect of 25(OH)D3 and 1,25(OH)2D3 on Th17 cell differentiation. Clin Immunol. 2016 May; 166-167:59-71. PMID: 27041081.
    Citations: 4     Fields:    Translation:HumansCells
  29. Alroughani R, Akhtar S, Ahmed SF, Khoury SJ, Al-Hashel JY, Sahraian MA, Al Jumah M, Zeineddine M, Farhat S, Doumiati H, Yamout BI. JC virus seroprevalence and seroconversion in multiple sclerosis cohort: A Middle-Eastern study. J Neurol Sci. 2016 Jan 15; 360:61-5. PMID: 26723975.
    Citations: 4     Fields:    Translation:HumansCells
  30. Orent W, Mchenry AR, Rao DA, White C, Klein HU, Bassil R, Srivastava G, Replogle JM, Raj T, Frangieh M, Cimpean M, Cuerdon N, Chibnik L, Khoury SJ, Karlson EW, Brenner MB, De Jager P, Bradshaw EM, Elyaman W. Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells. Hum Mol Genet. 2016 Jan 15; 25(2):404-17. PMID: 26604133.
    Citations: 2     Fields:    Translation:HumansCells
  31. Yamout BI, Zeineddine MM, Tamim H, Khoury SJ. Safety and efficacy of fingolimod in clinical practice: The experience of an academic center in the Middle East. J Neuroimmunol. 2015 Dec 15; 289:93-7. PMID: 26616877.
    Citations: 5     Fields:    Translation:Humans
  32. Darwish H, Zeinoun P, Ghusn H, Khoury B, Tamim H, Khoury SJ. Serum 25-hydroxyvitamin D predicts cognitive performance in adults. Neuropsychiatr Dis Treat. 2015; 11:2217-23. PMID: 26346368.
    Citations: 5     
  33. Merzaban JS, Imitola J, Starossom SC, Zhu B, Wang Y, Lee J, Ali AJ, Olah M, Abuelela AF, Khoury SJ, Sackstein R. Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosis. Glycobiology. 2015 Dec; 25(12):1392-409. PMID: 26153105.
    Citations: 13     Fields:    Translation:AnimalsCells
  34. Yamout B, Alroughani R, Al-Jumah M, Goueider R, Dahdaleh M, Inshasi J, Hashem S, Alsharoqi I, Sahraian M, Khoury S, Alkawi Z, Koussa S, Zakaria M, Al Khaburi J, Alsaadi T, Bohlega S. Consensus recommendations for the diagnosis and treatment of multiple sclerosis: the Middle East North Africa Committee for Treatment and Research In Multiple Sclerosis (MENACTRIMS). Curr Med Res Opin. 2015; 31(7):1349-61. PMID: 25946578.
    Citations:    
  35. Yamout BI, Zeineddine MM, Sawaya RA, Khoury SJ. Safety and efficacy of reduced fingolimod dosage treatment. J Neuroimmunol. 2015 Aug 15; 285:13-5. PMID: 26198913.
    Citations: 4     Fields:    Translation:HumansCells
  36. Mouhieddine TH, Darwish H, Fawaz L, Yamout B, Tamim H, Khoury SJ. Risk factors for multiple sclerosis and associations with anti-EBV antibody titers. Clin Immunol. 2015 May; 158(1):59-66. PMID: 25805657.
    Citations: 3     Fields:    Translation:HumansCells
  37. Kivisäkk P, Francois K, Mbianda J, Gandhi R, Weiner HL, Khoury SJ. Effect of natalizumab treatment on circulating plasmacytoid dendritic cells: a cross-sectional observational study in patients with multiple sclerosis. PLoS One. 2014; 9(7):e103716. PMID: 25075741.
    Citations: 3     Fields:    Translation:HumansCells
  38. Bassil R, Orent W, Olah M, Kurdi AT, Frangieh M, Buttrick T, Khoury SJ, Elyaman W. BCL6 controls Th9 cell development by repressing Il9 transcription. J Immunol. 2014 Jul 01; 193(1):198-207. PMID: 24879792.
    Citations: 15     Fields:    Translation:AnimalsCells
  39. Messina S, Vargas-Lowy D, Musallam A, Healy BC, Kivisakk P, Gandhi R, Bove R, Gholipour T, Khoury S, Weiner HL, Chitnis T. Increased leptin and A-FABP levels in relapsing and progressive forms of MS. BMC Neurol. 2013 Nov 11; 13:172. PMID: 24215402.
    Citations: 5     Fields:    Translation:Humans
  40. Ottoboni L, Frohlich IY, Lee M, Healy BC, Keenan BT, Xia Z, Chitnis T, Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, De Jager PL. Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus. Neurology. 2013 Nov 26; 81(22):1891-9. PMID: 24174586.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  41. Yamout B, El-Salem K, Gebeily S, Khoury S, Abu Zeid N, Hamoulila K, Alhalabi MS, Hasan ZN, Al Hamadani H, Hamoodi H, Al Omar A, Dahdaleh M. Multiple sclerosis in the Levant: a regional consensus statement. Int J Neurosci. 2014 May; 124(5):377-82. PMID: 23927564.
    Citations: 1     Fields:    Translation:Humans
  42. Kivisäkk P, Healy BC, Francois K, Gandhi R, Gholipour T, Egorova S, Sevdalinova V, Quintana F, Chitnis T, Weiner HL, Khoury SJ. Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development. Mult Scler. 2014 Apr; 20(4):438-44. PMID: 24005026.
    Citations: 9     Fields:    Translation:Humans
  43. Zhu B, Buttrick T, Bassil R, Zhu C, Olah M, Wu C, Xiao S, Orent W, Elyaman W, Khoury SJ. IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing Aldh1a2. J Immunol. 2013 Sep 15; 191(6):3139-51. PMID: 23960232.
    Citations: 14     Fields:    Translation:AnimalsCells
  44. Chitnis T, Khoury SJ. Sex influences in autoimmune disease. Clin Immunol. 2013 Nov; 149(2):169. PMID: 24012474.
    Citations:    Fields:    Translation:Humans
  45. Gandhi R, Healy B, Gholipour T, Egorova S, Musallam A, Hussain MS, Nejad P, Patel B, Hei H, Khoury S, Quintana F, Kivisakk P, Chitnis T, Weiner HL. Circulating microRNAs as biomarkers for disease staging in multiple sclerosis. Ann Neurol. 2013 Jun; 73(6):729-40. PMID: 23494648.
    Citations: 60     Fields:    Translation:Humans
  46. Bove R, Musallam A, Healy BC, Houtchens M, Glanz BI, Khoury S, Guttmann CR, De Jager PL, Chitnis T. No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50. BMC Neurol. 2013 Jul 03; 13:73. PMID: 23822612.
    Citations: 7     Fields:    Translation:Humans
  47. Yamout B, Alroughani R, Al-Jumah M, Khoury S, Abouzeid N, Dahdaleh M, Alsharoqi I, Inshasi J, Hashem S, Zakaria M, ElKallab K, Alsaadi T, Tawfeek T, Bohlega S. Consensus guidelines for the diagnosis and treatment of multiple sclerosis. Curr Med Res Opin. 2013 Jun; 29(6):611-21. PMID: 23514115.
    Citations: 3     Fields:    Translation:Humans
  48. Abrams P, Chapple C, Khoury S, Roehrborn C, de la Rosette J. Evaluation and treatment of lower urinary tract symptoms in older men. J Urol. 2013 Jan; 189(1 Suppl):S93-S101. PMID: 23234640.
    Citations: 16     Fields:    Translation:Humans
  49. Vargas-Lowy D, Kivisäkk P, Gandhi R, Raddassi K, Soltany P, Gorman MP, Khoury SJ, Chitnis T. Increased Th17 response to myelin peptides in pediatric MS. Clin Immunol. 2013 Mar; 146(3):176-84. PMID: 23352968.
    Citations: 4     Fields:    Translation:HumansCells
  50. Ottoboni L, Keenan BT, Tamayo P, Kuchroo M, Mesirov JP, Buckle GJ, Khoury SJ, Hafler DA, Weiner HL, De Jager PL. An RNA profile identifies two subsets of multiple sclerosis patients differing in disease activity. Sci Transl Med. 2012 Sep 26; 4(153):153ra131. PMID: 23019656.
    Citations: 19     Fields:    Translation:HumansCells
  51. Cousens LP, Najafian N, Mingozzi F, Elyaman W, Mazer B, Moise L, Messitt TJ, Su Y, Sayegh M, High K, Khoury SJ, Scott DW, De Groot AS. In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity. J Clin Immunol. 2013 Jan; 33 Suppl 1:S43-9. PMID: 22941509.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  52. Starossom SC, Mascanfroni ID, Imitola J, Cao L, Raddassi K, Hernandez SF, Bassil R, Croci DO, Cerliani JP, Delacour D, Wang Y, Elyaman W, Khoury SJ, Rabinovich GA. Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration. Immunity. 2012 Aug 24; 37(2):249-63. PMID: 22884314.
    Citations: 84     Fields:    Translation:HumansAnimalsCells
  53. Purwar R, Schlapbach C, Xiao S, Kang HS, Elyaman W, Jiang X, Jetten AM, Khoury SJ, Fuhlbrigge RC, Kuchroo VK, Clark RA, Kupper TS. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat Med. 2012 Aug; 18(8):1248-53. PMID: 22772464.
    Citations: 90     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  54. Elyaman W, Bassil R, Bradshaw EM, Orent W, Lahoud Y, Zhu B, Radtke F, Yagita H, Khoury SJ. Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells. Immunity. 2012 Apr 20; 36(4):623-34. PMID: 22503540.
    Citations: 43     Fields:    Translation:AnimalsCells
  55. Ceccarelli A, Jackson JS, Tauhid S, Arora A, Gorky J, Dell'Oglio E, Bakshi A, Chitnis T, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R, Neema M. The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis. AJNR Am J Neuroradiol. 2012 Sep; 33(8):1579-85. PMID: 22460341.
    Citations: 28     Fields:    Translation:Humans
  56. Okada H, Khoury SJ. Type17 T-cells in central nervous system autoimmunity and tumors. J Clin Immunol. 2012 Aug; 32(4):802-8. PMID: 22454247.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  57. Zhu B, Trikudanathan S, Zozulya AL, Sandoval-Garcia C, Kennedy JK, Atochina O, Norberg T, Castagner B, Seeberger P, Fabry Z, Harn D, Khoury SJ, Guleria I. Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis. Clin Immunol. 2012 Mar; 142(3):351-61. PMID: 22264636.
    Citations: 8     Fields:    Translation:AnimalsCells
  58. Moodie J, Healy BC, Buckle GJ, Gauthier SA, Glanz BI, Arora A, Ceccarelli A, Tauhid S, Han XM, Venkataraman A, Chitnis T, Khoury SJ, Guttmann CR, Weiner HL, Neema M, Bakshi R. Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study. J Neurol Sci. 2012 Apr 15; 315(1-2):49-54. PMID: 22209496.
    Citations: 8     Fields:    Translation:Humans
  59. Comabella M, Khoury SJ. Therapeutic strategies in multiple sclerosis. Clin Immunol. 2012 Jan; 142(1):1. PMID: 22155340.
    Citations:    Fields:    Translation:Humans
  60. Elyaman W, Khoury SJ, Scott DW, De Groot AS. Potential application of tregitopes as immunomodulating agents in multiple sclerosis. Neurol Res Int. 2011; 2011:256460. PMID: 21941651.
    Citations: 9     
  61. Zhu B, Kennedy JK, Wang Y, Sandoval-Garcia C, Cao L, Xiao S, Wu C, Elyaman W, Khoury SJ. Plasticity of Ly-6C(hi) myeloid cells in T cell regulation. J Immunol. 2011 Sep 01; 187(5):2418-32. PMID: 21824867.
    Citations: 25     Fields:    Translation:AnimalsCells
  62. Bassil R, Zhu B, Lahoud Y, Riella LV, Yagita H, Elyaman W, Khoury SJ. Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development. J Immunol. 2011 Sep 01; 187(5):2322-8. PMID: 21813770.
    Citations: 24     Fields:    Translation:AnimalsCells
  63. Stankiewicz JM, Glanz BI, Healy BC, Arora A, Neema M, Benedict RH, Guss ZD, Tauhid S, Buckle GJ, Houtchens MK, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R. Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis. J Neuroimaging. 2011 Apr; 21(2):e50-6. PMID: 19888926.
    Citations: 32     Fields:    Translation:Humans
  64. Holland CM, Charil A, Csapo I, Liptak Z, Ichise M, Khoury SJ, Bakshi R, Weiner HL, Guttmann CR. The relationship between normal cerebral perfusion patterns and white matter lesion distribution in 1,249 patients with multiple sclerosis. J Neuroimaging. 2012 Apr; 22(2):129-36. PMID: 21447022.
    Citations: 14     Fields:    Translation:HumansCells
  65. Khoury SJ. Th17 and Treg balance in systemic sclerosis. Clin Immunol. 2011 Jun; 139(3):231-2. PMID: 21482482.
    Citations: 7     Fields:    Translation:HumansCells
  66. Liguori M, Meier DS, Hildenbrand P, Healy BC, Chitnis T, Baruch NF, Khoury SJ, Weiner HL, Bakshi R, Barkhof F, Guttmann CR. One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2011 Oct; 82(10):1125-31. PMID: 21429902.
    Citations: 2     Fields:    Translation:Humans
  67. Comabella M, Khoury SJ. Immunopathogenesis of multiple sclerosis. Clin Immunol. 2012 Jan; 142(1):2-8. PMID: 21458377.
    Citations: 28     Fields:    Translation:Humans
  68. Rasmussen S, Imitola J, Ayuso-Sacido A, Wang Y, Starossom SC, Kivisäkk P, Zhu B, Meyer M, Bronson RT, Garcia-Verdugo JM, Khoury SJ. Reversible neural stem cell niche dysfunction in a model of multiple sclerosis. Ann Neurol. 2011 May; 69(5):878-91. PMID: 21391234.
    Citations: 32     Fields:    Translation:AnimalsCellsPHPublic Health
  69. Imitola J, Côté D, Rasmussen S, Xie XS, Liu Y, Chitnis T, Sidman RL, Lin CP, Khoury SJ. Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice. J Biomed Opt. 2011 Feb; 16(2):021109. PMID: 21361672.
    Citations: 19     Fields:    Translation:AnimalsCells
  70. Liguori M, Healy BC, Glanz BI, Khoury SJ, Moscufo N, Weiner HL, De Jager PL, Guttmann CR. HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study. Genes Immun. 2011 Apr; 12(3):183-90. PMID: 21179117.
    Citations: 2     Fields:    Translation:Humans
  71. Khoury S, Bakshi R. Cerebral pseudoatrophy or real atrophy after therapy in multiple sclerosis. Ann Neurol. 2010 Dec; 68(6):778-9. PMID: 21194148.
    Citations: 9     Fields:    Translation:Humans
  72. Xia Z, Chibnik LB, Glanz BI, Liguori M, Shulman JM, Tran D, Khoury SJ, Chitnis T, Holyoak T, Weiner HL, Guttmann CR, De Jager PL. A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis. PLoS One. 2010 Nov 30; 5(11):e14169. PMID: 21152065.
    Citations: 9     Fields:    Translation:Humans
  73. Gross R, Healy BC, Cepok S, Chitnis T, Khoury SJ, Hemmer B, Weiner HL, Hafler DA, De Jager PL. Population structure and HLA DRB1 1501 in the response of subjects with multiple sclerosis to first-line treatments. J Neuroimmunol. 2011 Apr; 233(1-2):168-74. PMID: 21115201.
    Citations: 7     Fields:    Translation:Humans
  74. Starossom SC, Imitola J, Wang Y, Cao L, Khoury SJ. Subventricular zone microglia transcriptional networks. Brain Behav Immun. 2011 Jul; 25(5):991-9. PMID: 21074605.
    Citations: 3     Fields:    Translation:AnimalsCells
  75. Khoury SJ, Healy BC, Kivisäkk P, Viglietta V, Egorova S, Guttmann CR, Wedgwood JF, Hafler DA, Weiner HL, Buckle G, Cook S, Reddy S. A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis. Arch Neurol. 2010 Sep; 67(9):1055-61. PMID: 20837847.
    Citations: 7     Fields:    Translation:Humans
  76. Healy BC, Liguori M, Tran D, Chitnis T, Glanz B, Wolfish C, Gauthier S, Buckle G, Houtchens M, Stazzone L, Khoury S, Hartzmann R, Fernandez-Vina M, Hafler DA, Weiner HL, Guttmann CR, De Jager PL. HLA B*44: protective effects in MS susceptibility and MRI outcome measures. Neurology. 2010 Aug 17; 75(7):634-40. PMID: 20713950.
    Citations: 19     Fields:    Translation:Humans
  77. Beriou G, Bradshaw EM, Lozano E, Costantino CM, Hastings WD, Orban T, Elyaman W, Khoury SJ, Kuchroo VK, Baecher-Allan C, Hafler DA. TGF-beta induces IL-9 production from human Th17 cells. J Immunol. 2010 Jul 01; 185(1):46-54. PMID: 20498357.
    Citations: 48     Fields:    Translation:HumansCells
  78. Liu Y, Bando Y, Vargas-Lowy D, Elyaman W, Khoury SJ, Huang T, Reif K, Chitnis T. CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis. J Neurosci. 2010 Feb 10; 30(6):2025-38. PMID: 20147531.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  79. Abrams P, Andersson KE, Birder L, Brubaker L, Cardozo L, Chapple C, Cottenden A, Davila W, de Ridder D, Dmochowski R, Drake M, Dubeau C, Fry C, Hanno P, Smith JH, Herschorn S, Hosker G, Kelleher C, Koelbl H, Khoury S, Madoff R, Milsom I, Moore K, Newman D, Nitti V, Norton C, Nygaard I, Payne C, Smith A, Staskin D, Tekgul S, Thuroff J, Tubaro A, Vodusek D, Wein A, Wyndaele JJ. Fourth International Consultation on Incontinence Recommendations of the International Scientific Committee: Evaluation and treatment of urinary incontinence, pelvic organ prolapse, and fecal incontinence. Neurourol Urodyn. 2010; 29(1):213-40. PMID: 20025020.
    Citations: 170     Fields:    Translation:Humans
  80. Ilan Y, Zigmond E, Lalazar G, Dembinsky A, Ben Ya'acov A, Hemed N, Kasis I, Axelrod E, Zolotarov L, Klein A, El Haj M, Gandhi R, Baecher-Allan C, Wu H, Murugaiyan G, Kivisakk P, Farez MF, Quintana FJ, Khoury SJ, Weiner HL. Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells. J Clin Immunol. 2010 Jan; 30(1):167-77. PMID: 19756989.
    Citations: 21     Fields:    Translation:HumansCellsCTClinical Trials
  81. McLaughlin KA, Chitnis T, Newcombe J, Franz B, Kennedy J, McArdel S, Kuhle J, Kappos L, Rostasy K, Pohl D, Gagne D, Ness JM, Tenembaum S, O'Connor KC, Viglietta V, Wong SJ, Tavakoli NP, de Seze J, Idrissova Z, Khoury SJ, Bar-Or A, Hafler DA, Banwell B, Wucherpfennig KW. Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis. J Immunol. 2009 Sep 15; 183(6):4067-76. PMID: 19687098.
    Citations: 50     Fields:    Translation:HumansCells
  82. Healy BC, Ali EN, Guttmann CR, Chitnis T, Glanz BI, Buckle G, Houtchens M, Stazzone L, Moodie J, Berger AM, Duan Y, Bakshi R, Khoury S, Weiner H, Ascherio A. Smoking and disease progression in multiple sclerosis. Arch Neurol. 2009 Jul; 66(7):858-64. PMID: 19597087.
    Citations: 33     Fields:    Translation:Humans
  83. Kivisäkk P, Healy BC, Viglietta V, Quintana FJ, Hootstein MA, Weiner HL, Khoury SJ. Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells. Neurology. 2009 Jun 02; 72(22):1922-30. PMID: 19487650.
    Citations: 44     Fields:    Translation:HumansCells
  84. Elyaman W, Bradshaw EM, Uyttenhove C, Dardalhon V, Awasthi A, Imitola J, Bettelli E, Oukka M, van Snick J, Renauld JC, Kuchroo VK, Khoury SJ. IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells. Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):12885-90. PMID: 19433802.
    Citations: 135     Fields:    Translation:AnimalsCells
  85. Gauthier SA, Glanz BI, Mandel M, Tsagkaropoulos A, Neema M, Stankiewicz J, Arora A, Duan Y, Liptak Z, Egorova S, Buckle GJ, Bakshi R, Guttmann CR, Khoury SJ, Weiner HL. Incidence and factors associated with treatment failure in the CLIMB multiple sclerosis cohort study. J Neurol Sci. 2009 Sep 15; 284(1-2):116-9. PMID: 19428028.
    Citations: 5     Fields:    Translation:Humans
  86. Kivisäkk P, Imitola J, Rasmussen S, Elyaman W, Zhu B, Ransohoff RM, Khoury SJ. Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis. Ann Neurol. 2009 Apr; 65(4):457-69. PMID: 18496841.
    Citations: 91     Fields:    Translation:AnimalsCells
  87. Gauthier SA, Berger AM, Liptak Z, Duan Y, Egorova S, Buckle GJ, Glanz BI, Khoury SJ, Bakshi R, Weiner HL, Guttmann CR. Rate of brain atrophy in benign vs early multiple sclerosis. Arch Neurol. 2009 Feb; 66(2):234-7. PMID: 19204160.
    Citations: 9     Fields:    Translation:Humans
  88. Ali EN, Healy BC, Stazzone LA, Brown BA, Weiner HL, Khoury SJ. Daclizumab in treatment of multiple sclerosis patients. Mult Scler. 2009 Feb; 15(2):272-4. PMID: 19136546.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  89. Neema M, Arora A, Healy BC, Guss ZD, Brass SD, Duan Y, Buckle GJ, Glanz BI, Stazzone L, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R. Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis. J Neuroimaging. 2009 Jan; 19(1):3-8. PMID: 19192042.
    Citations: 29     Fields:    Translation:Humans
  90. Wang Y, Evans JT, Rodriguez F, Fields P, Mueller C, Chitnis T, Khoury SJ, Bynoe MS. A tale of two STAT6 knock out mice in the induction of experimental autoimmune encephalomyelitis. J Neuroimmunol. 2009 Jan 03; 206(1-2):76-85. PMID: 19100630.
    Citations: 5     Fields:    Translation:AnimalsCells
  91. Quintana FJ, Farez MF, Viglietta V, Iglesias AH, Merbl Y, Izquierdo G, Lucas M, Basso AS, Khoury SJ, Lucchinetti CF, Cohen IR, Weiner HL. Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis. Proc Natl Acad Sci U S A. 2008 Dec 02; 105(48):18889-94. PMID: 19028871.
    Citations: 82     Fields:    Translation:HumansAnimals
  92. Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho IC, Khoury S, Oukka M, Kuchroo VK. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat Immunol. 2008 Dec; 9(12):1347-55. PMID: 18997793.
    Citations: 352     Fields:    Translation:AnimalsCells
  93. Bakshi R, Neema M, Healy BC, Liptak Z, Betensky RA, Buckle GJ, Gauthier SA, Stankiewicz J, Meier D, Egorova S, Arora A, Guss ZD, Glanz B, Khoury SJ, Guttmann CR, Weiner HL. Predicting clinical progression in multiple sclerosis with the magnetic resonance disease severity scale. Arch Neurol. 2008 Nov; 65(11):1449-53. PMID: 19001162.
    Citations: 16     Fields:    Translation:Humans
  94. Wang Y, Imitola J, Rasmussen S, O'Connor KC, Khoury SJ. Paradoxical dysregulation of the neural stem cell pathway sonic hedgehog-Gli1 in autoimmune encephalomyelitis and multiple sclerosis. Ann Neurol. 2008 Oct; 64(4):417-27. PMID: 18991353.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  95. Viglietta V, Bourcier K, Buckle GJ, Healy B, Weiner HL, Hafler DA, Egorova S, Guttmann CR, Rusche JR, Khoury SJ. CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial. Neurology. 2008 Sep 16; 71(12):917-24. PMID: 18794494.
    Citations: 30     Fields:    Translation:HumansCTClinical Trials
  96. Pluchino S, Muzio L, Imitola J, Deleidi M, Alfaro-Cervello C, Salani G, Porcheri C, Brambilla E, Cavasinni F, Bergamaschi A, Garcia-Verdugo JM, Comi G, Khoury SJ, Martino G. Persistent inflammation alters the function of the endogenous brain stem cell compartment. Brain. 2008 Oct; 131(Pt 10):2564-78. PMID: 18757884.
    Citations: 83     Fields:    Translation:AnimalsCells
  97. Lavigne GJ, Khoury S, Abe S, Yamaguchi T, Raphael K. Bruxism physiology and pathology: an overview for clinicians. J Oral Rehabil. 2008 Jul; 35(7):476-94. PMID: 18557915.
    Citations: 69     Fields:    Translation:Humans
  98. Elyaman W, Kivisäkk P, Reddy J, Chitnis T, Raddassi K, Imitola J, Bradshaw E, Kuchroo VK, Yagita H, Sayegh MH, Khoury SJ. Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis. Am J Pathol. 2008 Aug; 173(2):411-22. PMID: 18583313.
    Citations: 21     Fields:    Translation:AnimalsCells
  99. De Jager PL, Rossin E, Pyne S, Tamayo P, Ottoboni L, Viglietta V, Weiner M, Soler D, Izmailova E, Faron-Yowe L, O'Brien C, Freeman S, Granados S, Parker A, Roubenoff R, Mesirov JP, Khoury SJ, Hafler DA, Weiner HL. Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells. Brain. 2008 Jul; 131(Pt 7):1701-11. PMID: 18567923.
    Citations: 24     Fields:    Translation:HumansCells
  100. Liptak Z, Berger AM, Sampat MP, Charil A, Felsovalyi O, Healy BC, Hildenbrand P, Khoury SJ, Weiner HL, Bakshi R, Guttmann CR. Medulla oblongata volume: a biomarker of spinal cord damage and disability in multiple sclerosis. AJNR Am J Neuroradiol. 2008 Sep; 29(8):1465-70. PMID: 18556361.
    Citations: 10     Fields:    Translation:Humans
  101. Villoslada P, Moreno B, Melero I, Pablos JL, Martino G, Uccelli A, Montalban X, Avila J, Rivest S, Acarin L, Appel S, Khoury SJ, McGeer P, Ferrer I, Delgado M, Obeso J, Schwartz M. Immunotherapy for neurological diseases. Clin Immunol. 2008 Sep; 128(3):294-305. PMID: 18534912.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  102. Imitola J, Khoury SJ. Neural stem cells and the future treatment of neurological diseases: raising the standard. Methods Mol Biol. 2008; 438:9-16. PMID: 18369745.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  103. Krishnamoorthy M, Roy-Chaudhury P, Wang Y, Sinha Roy A, Zhang J, Khoury S, Munda R, Banerjee R. Measurement of hemodynamic and anatomic parameters in a swine arteriovenous fistula model. J Vasc Access. 2008 Jan-Mar; 9(1):28-34. PMID: 18379977.
    Citations: 2     Fields:    Translation:Animals
  104. Elyaman W, Bradshaw EM, Wang Y, Oukka M, Kivisäkk P, Chiba S, Yagita H, Khoury SJ. JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis. J Immunol. 2007 Nov 01; 179(9):5990-8. PMID: 17947672.
    Citations: 38     Fields:    Translation:AnimalsCells
  105. Zhu B, Bando Y, Xiao S, Yang K, Anderson AC, Kuchroo VK, Khoury SJ. CD11b+Ly-6C(hi) suppressive monocytes in experimental autoimmune encephalomyelitis. J Immunol. 2007 Oct 15; 179(8):5228-37. PMID: 17911608.
    Citations: 140     Fields:    Translation:AnimalsCells
  106. Imitola J. Prospects for neural stem cell-based therapies for neurological diseases. Neurotherapeutics. 2007 Oct; 4(4):701-14. PMID: 17920551.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  107. Viglietta V, Khoury SJ. Modulating co-stimulation. Neurotherapeutics. 2007 Oct; 4(4):666-75. PMID: 17920548.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  108. Rasmussen S, Wang Y, Kivisäkk P, Bronson RT, Meyer M, Imitola J, Khoury SJ. Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing--remitting experimental autoimmune encephalomyelitis. Brain. 2007 Nov; 130(Pt 11):2816-29. PMID: 17890734.
    Citations: 55     Fields:    Translation:AnimalsCells
  109. Glanz BI, Holland CM, Gauthier SA, Amunwa EL, Liptak Z, Houtchens MK, Sperling RA, Khoury SJ, Guttmann CR, Weiner HL. Cognitive dysfunction in patients with clinically isolated syndromes or newly diagnosed multiple sclerosis. Mult Scler. 2007 Sep; 13(8):1004-10. PMID: 17623735.
    Citations: 32     Fields:    Translation:Humans
  110. Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, Imitola J, Korn T, Anderson AC, Zhang Z, Gutierrez C, Moll T, Sobel RA, Umetsu DT, Yagita H, Akiba H, Strom T, Sayegh MH, DeKruyff RH, Khoury SJ, Kuchroo VK. Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function. J Exp Med. 2007 Jul 09; 204(7):1691-702. PMID: 17606630.
    Citations: 56     Fields:    Translation:AnimalsCells
  111. Gauthier SA, Mandel M, Guttmann CR, Glanz BI, Khoury SJ, Betensky RA, Weiner HL. Predicting short-term disability in multiple sclerosis. Neurology. 2007 Jun 12; 68(24):2059-65. PMID: 17562826.
    Citations: 23     Fields:    Translation:Humans
  112. Chitnis T, Imitola J, Wang Y, Elyaman W, Chawla P, Sharuk M, Raddassi K, Bronson RT, Khoury SJ. Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration. Am J Pathol. 2007 May; 170(5):1695-712. PMID: 17456775.
    Citations: 57     Fields:    Translation:AnimalsCells
  113. Kaneko S, Wang J, Kaneko M, Yiu G, Hurrell JM, Chitnis T, Khoury SJ, He Z. Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models. J Neurosci. 2006 Sep 20; 26(38):9794-804. PMID: 16988050.
    Citations: 50     Fields:    Translation:AnimalsCells
  114. Karni A, Abraham M, Monsonego A, Cai G, Freeman GJ, Hafler D, Khoury SJ, Weiner HL. Innate immunity in multiple sclerosis: myeloid dendritic cells in secondary progressive multiple sclerosis are activated and drive a proinflammatory immune response. J Immunol. 2006 Sep 15; 177(6):4196-202. PMID: 16951385.
    Citations: 43     Fields:    Translation:HumansCells
  115. Laplaud DA, Berthelot L, Miqueu P, Bourcier K, Moynard J, Oudinet Y, Guillet M, Ruiz C, Oden N, Brouard S, Guttmann CR, Weiner HL, Khoury SJ, Soulillou JP. Serial blood T cell repertoire alterations in multiple sclerosis patients; correlation with clinical and MRI parameters. J Neuroimmunol. 2006 Aug; 177(1-2):151-60. PMID: 16806500.
    Citations: 5     Fields:    Translation:HumansCells
  116. Monsonego A, Imitola J, Petrovic S, Zota V, Nemirovsky A, Baron R, Fisher Y, Owens T, Weiner HL. Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2006 Mar 28; 103(13):5048-53. PMID: 16549802.
    Citations: 44     Fields:    Translation:AnimalsCellsPHPublic Health
  117. Zhu B, Guleria I, Khosroshahi A, Chitnis T, Imitola J, Azuma M, Yagita H, Sayegh MH, Khoury SJ. Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis. J Immunol. 2006 Mar 15; 176(6):3480-9. PMID: 16517716.
    Citations: 41     Fields:    Translation:AnimalsCells
  118. Imitola J, Chitnis T, Khoury SJ. Insights into the molecular pathogenesis of progression in multiple sclerosis: potential implications for future therapies. Arch Neurol. 2006 Jan; 63(1):25-33. PMID: 16401734.
    Citations: 24     Fields:    Translation:Humans
  119. Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, Khoury SJ, Zheng XX, Strom TB, Kuchroo VK. The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol. 2005 Dec; 6(12):1245-52. PMID: 16286920.
    Citations: 417     Fields:    Translation:AnimalsCells
  120. Guleria I, Khosroshahi A, Ansari MJ, Habicht A, Azuma M, Yagita H, Noelle RJ, Coyle A, Mellor AL, Khoury SJ, Sayegh MH. A critical role for the programmed death ligand 1 in fetomaternal tolerance. J Exp Med. 2005 Jul 18; 202(2):231-7. PMID: 16027236.
    Citations: 90     Fields:    Translation:AnimalsCells
  121. Camelo S, Iglesias AH, Hwang D, Due B, Ryu H, Smith K, Gray SG, Imitola J, Duran G, Assaf B, Langley B, Khoury SJ, Stephanopoulos G, De Girolami U, Ratan RR, Ferrante RJ, Dangond F. Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis. J Neuroimmunol. 2005 Jul; 164(1-2):10-21. PMID: 15885809.
    Citations: 87     Fields:    Translation:AnimalsCells
  122. Benou C, Wang Y, Imitola J, VanVlerken L, Chandras C, Karalis KP, Khoury SJ. Corticotropin-releasing hormone contributes to the peripheral inflammatory response in experimental autoimmune encephalomyelitis. J Immunol. 2005 May 01; 174(9):5407-13. PMID: 15843539.
    Citations: 9     Fields:    Translation:AnimalsCells
  123. Prat A, Biernacki K, Saroli T, Orav JE, Guttmann CR, Weiner HL, Khoury SJ, Antel JP. Kinin B1 receptor expression on multiple sclerosis mononuclear cells: correlation with magnetic resonance imaging T2-weighted lesion volume and clinical disability. Arch Neurol. 2005 May; 62(5):795-800. PMID: 15883268.
    Citations: 9     Fields:    Translation:HumansCells
  124. Chitnis T, Imitola J, Khoury SJ. Therapeutic strategies to prevent neurodegeneration and promote regeneration in multiple sclerosis. Curr Drug Targets Immune Endocr Metabol Disord. 2005 Mar; 5(1):11-26. PMID: 15777201.
    Citations: 8     Fields:    Translation:HumansAnimals
  125. Kutok JL, Yang X, Folkerth RD, Imitola J, Raddassi K, Yano Y, Salahuddin S, Lawitts J, Imboden H, Chinami M, Shirakawa T, Turner H, Khoury S, Sayegh MH, Scadden D, Adra C. The cell cycle associated protein, HTm4, is expressed in differentiating cells of the hematopoietic and central nervous system in mice. J Mol Histol. 2005 Feb; 36(1-2):77-87. PMID: 15704002.
    Citations: 4     Fields:    Translation:AnimalsCells
  126. Imitola J, Chitnis T, Khoury SJ. Cytokines in multiple sclerosis: from bench to bedside. Pharmacol Ther. 2005 May; 106(2):163-77. PMID: 15866318.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  127. Mueller FJ, McKercher SR, Imitola J, Loring JF, Yip S, Khoury SJ, Snyder EY. At the interface of the immune system and the nervous system: how neuroinflammation modulates the fate of neural progenitors in vivo. Ernst Schering Res Found Workshop. 2005; (53):83-114. PMID: 16315610.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  128. Imitola J, Raddassi K, Park KI, Mueller FJ, Nieto M, Teng YD, Frenkel D, Li J, Sidman RL, Walsh CA, Snyder EY, Khoury SJ. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci U S A. 2004 Dec 28; 101(52):18117-22. PMID: 15608062.
    Citations: 308     Fields:    Translation:HumansAnimalsCells
  129. Nieto M, Monuki ES, Tang H, Imitola J, Haubst N, Khoury SJ, Cunningham J, Gotz M, Walsh CA. Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex. J Comp Neurol. 2004 Nov 08; 479(2):168-80. PMID: 15452856.
    Citations: 159     Fields:    Translation:AnimalsCells
  130. Magee CC, Denton MD, Womer KL, Khoury SJ, Sayegh MH. Assessment by flow cytometry of intracellular cytokine production in the peripheral blood cells of renal transplant recipients. Clin Transplant. 2004 Aug; 18(4):395-401. PMID: 15233816.
    Citations: 3     Fields:    Translation:HumansCells
  131. Meier DS, Weiner HL, Khoury SJ, Guttmann CR. Magnetic resonance imaging surrogates of multiple sclerosis pathology and their relationship to central nervous system atrophy. J Neuroimaging. 2004 Jul; 14(3 Suppl):46S-53S. PMID: 15228759.
    Citations: 4     Fields:    Translation:Humans
  132. Imitola J, Park KI, Teng YD, Nisim S, Lachyankar M, Ourednik J, Mueller FJ, Yiou R, Atala A, Sidman RL, Tuszynski M, Khoury SJ, Snyder EY. Stem cells: cross-talk and developmental programs. Philos Trans R Soc Lond B Biol Sci. 2004 May 29; 359(1445):823-37. PMID: 15293810.
    Citations: 12     Fields:    Translation:HumansCells
  133. Imitola J, Comabella M, Chandraker AK, Dangond F, Sayegh MH, Snyder EY, Khoury SJ. Neural stem/progenitor cells express costimulatory molecules that are differentially regulated by inflammatory and apoptotic stimuli. Am J Pathol. 2004 May; 164(5):1615-25. PMID: 15111308.
    Citations: 26     Fields:    Translation:AnimalsCells
  134. Khoury SJ, Sayegh MH. The roles of the new negative T cell costimulatory pathways in regulating autoimmunity. Immunity. 2004 May; 20(5):529-38. PMID: 15142522.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  135. Chitnis T, Salama AD, Grusby MJ, Sayegh MH, Khoury SJ. Defining Th1 and Th2 immune responses in a reciprocal cytokine environment in vivo. J Immunol. 2004 Apr 01; 172(7):4260-5. PMID: 15034039.
    Citations: 4     Fields:    Translation:AnimalsCells
  136. Karni A, Balashov K, Hancock WW, Bharanidharan P, Abraham M, Khoury SJ, Weiner HL. Cyclophosphamide modulates CD4+ T cells into a T helper type 2 phenotype and reverses increased IFN-gamma production of CD8+ T cells in secondary progressive multiple sclerosis. J Neuroimmunol. 2004 Jan; 146(1-2):189-98. PMID: 14698862.
    Citations: 10     Fields:    Translation:HumansCells
  137. Sheen VL, Ganesh VS, Topcu M, Sebire G, Bodell A, Hill RS, Grant PE, Shugart YY, Imitola J, Khoury SJ, Guerrini R, Walsh CA. Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex. Nat Genet. 2004 Jan; 36(1):69-76. PMID: 14647276.
    Citations: 86     Fields:    Translation:HumansAnimalsCells
  138. Chitnis T, Khoury SJ. Role of costimulatory pathways in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis. J Allergy Clin Immunol. 2003 Nov; 112(5):837-49; quiz 850. PMID: 14610467.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  139. Najafian N, Chitnis T, Salama AD, Zhu B, Benou C, Yuan X, Clarkson MR, Sayegh MH, Khoury SJ. Regulatory functions of CD8+CD28- T cells in an autoimmune disease model. J Clin Invest. 2003 Oct; 112(7):1037-48. PMID: 14523041.
    Citations: 72     Fields:    Translation:AnimalsCells
  140. Monsonego A, Imitola J, Zota V, Oida T, Weiner HL. Microglia-mediated nitric oxide cytotoxicity of T cells following amyloid beta-peptide presentation to Th1 cells. J Immunol. 2003 Sep 01; 171(5):2216-24. PMID: 12928365.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  141. Imitola J, Snyder EY, Khoury SJ. Genetic programs and responses of neural stem/progenitor cells during demyelination: potential insights into repair mechanisms in multiple sclerosis. Physiol Genomics. 2003 Aug 15; 14(3):171-97. PMID: 12923300.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  142. Salama AD, Chitnis T, Imitola J, Ansari MJ, Akiba H, Tushima F, Azuma M, Yagita H, Sayegh MH, Khoury SJ. Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J Exp Med. 2003 Jul 07; 198(1):71-8. PMID: 12847138.
    Citations: 130     Fields:    Tra