Harvard Catalyst Profiles

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Peter Andrija Nigrovic, M.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R21AR076630 (NIGROVIC, PETER A) Feb 1, 2020 - Jan 31, 2022
    NIH
    Modulation of neutrophil function through emperipolesis
    Role: Principal Investigator
  2. R21HL150575 (NIGROVIC, PETER A) Jan 1, 2020 - Dec 31, 2021
    NIH
    Impact of emperipolesis on platelet function
    Role: Principal Investigator
  3. R01AR075906 (NIGROVIC, PETER A) Jul 1, 2019 - May 31, 2024
    NIH
    T resident memory cells in arthritis
    Role: Principal Investigator
  4. R01AR073201 (NIGROVIC, PETER A) Dec 1, 2018 - Nov 30, 2023
    NIH
    Bridging the gap between GWAS and mechanism in JIA
    Role: Principal Investigator
  5. P30AR070253 (NIGROVIC, PETER A) Aug 11, 2016 - Jul 31, 2026
    NIH
    Joint Biology Consortium Resource-based Center
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Beukelman T, Tomlinson G, Nigrovic PA, Dennos A, Del Gaizo V, Jelinek M, Riordan ME, Schanberg LE, Mohan S, Pfeifer E, Kimura Y. First-line options for systemic juvenile idiopathic arthritis treatment: an observational study of Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans. Pediatr Rheumatol Online J. 2022 Dec 08; 20(1):113. PMID: 36482434; PMCID: PMC9730566.
    Citations:    Fields:    Translation:Humans
  2. Huang Z, You X, Chen L, Du Y, Brodeur K, Jee H, Wang Q, Linder G, Darbousset R, Cunin P, Chang MH, Wactor A, Wauford BM, Todd MJC, Wei K, Li Y, Levescot A, Iwakura Y, Pascual V, Baldwin NE, Quartier P, Li T, Gianatasio MT, Hasserjian RP, Henderson LA, Sykes DB, Mellins ED, Canna SW, Charles JF, Nigrovic PA, Lee PY. mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome. Nat Commun. 2022 11 28; 13(1):6915. PMID: 36443301; PMCID: PMC9705324.
    Citations:    Fields:    Translation:HumansAnimals
  3. Chang MH, Bocharnikov AV, Case SM, Todd M, Laird-Gion J, Alvarez-Baumgartner M, Nigrovic PA. Joint-Specific Memory and Sustained Risk for New Joint Accumulation in Autoimmune Arthritis. Arthritis Rheumatol. 2022 11; 74(11):1851-1858. PMID: 35606924; PMCID: PMC9617751.
    Citations:    Fields:    
  4. Grayson PC, Beck DB, Ferrada MA, Nigrovic PA, Kastner DL. VEXAS Syndrome and Disease Taxonomy in Rheumatology. Arthritis Rheumatol. 2022 11; 74(11):1733-1736. PMID: 35696333; PMCID: PMC9617773.
    Citations:    Fields:    
  5. Agrawal M, Niroula A, Cunin P, McConkey M, Shkolnik V, Kim PG, Wong WJ, Weeks LD, Lin AE, Miller PG, Gibson CJ, Sekar A, Schaefer IM, Neuberg D, Stone RM, Bick AG, Uddin MM, Griffin GK, Jaiswal S, Natarajan P, Nigrovic PA, Rao DA, Ebert BL. TET2-mutant clonal hematopoiesis and risk of gout. Blood. 2022 09 08; 140(10):1094-1103. PMID: 35714308; PMCID: PMC9461470.
    Citations:    Fields:    
  6. Stoll ML, DeQuattro K, Li Z, Sawhney H, Weiss PF, Nigrovic PA, Wright TB, Schikler K, Edelheit B, Morrow CD, Reveille JD, Brown MA, Gensler LS. Correction: Stoll et al. Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients. Children 2022, 9, 569. Children (Basel). 2022 Aug 02; 9(8). PMID: 36010158; PMCID: PMC9406925.
    Citations: 1     
  7. Taylor ML, Hoyt KJ, Han J, Benson L, Case S, Chandler MT, Chang MH, Platt C, Cohen EM, Day-Lewis M, Dedeoglu F, Gorman M, Hausmann JS, Janssen E, Lee PY, Lo J, Priebe GP, Lo MS, Meidan E, Nigrovic PA, Roberts JE, Son MBF, Sundel RP, Alfieri M, Yeun JC, Shobiye DM, Degar B, Chang JC, Halyabar O, Hazen MM, Henderson LA. An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome. J Rheumatol. 2022 Sep; 49(9):1042-1051. PMID: 35840156; PMCID: PMC9588491.
    Citations:    Fields:    
  8. Binstadt BA, Nigrovic PA. The Conundrum of Lung Disease and Drug Hypersensitivity-like Reactions in Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2022 07; 74(7):1122-1131. PMID: 35413159; PMCID: PMC9367674.
    Citations:    Fields:    Translation:Humans
  9. Solomon DH, Bucala R, Kaplan MJ, Nigrovic PA. Arthritis & Rheumatology: "Mid-Term" Report. Arthritis Rheumatol. 2022 07; 74(7):1099-1101. PMID: 35358367.
    Citations:    Fields:    Translation:Humans
  10. Stoll ML, DeQuattro K, Li Z, Sawhney H, Weiss PF, Nigrovic PA, Wright TB, Schikler K, Edelheit B, Morrow CD, Reveille JD, Brown MA, Gensler LS. Impact of HLA-B27 and Disease Status on the Gut Microbiome of the Offspring of Ankylosing Spondylitis Patients. Children (Basel). 2022 Apr 16; 9(4). PMID: 35455612; PMCID: PMC9030797.
    Citations:    
  11. Huang FY, Cunin P, Radtke FA, Darbousset R, Grieshaber-Bouyer R, Nigrovic PA. Neutrophil transit time and localization within the megakaryocyte define morphologically distinct forms of emperipolesis. Blood Adv. 2022 04 12; 6(7):2081-2091. PMID: 34872109; PMCID: PMC9006297.
    Citations:    Fields:    Translation:AnimalsCells
  12. Case SM, Nigrovic PA. Implications of Evolving Disease Classification for Drug Approval in Juvenile Idiopathic Arthritis. Paediatr Drugs. 2022 May; 24(3):185-191. PMID: 35364780.
    Citations:    Fields:    Translation:Humans
  13. Onel KB, Horton DB, Lovell DJ, Shenoi S, Cuello CA, Angeles-Han ST, Becker ML, Cron RQ, Feldman BM, Ferguson PJ, Gewanter H, Guzman J, Kimura Y, Lee T, Murphy K, Nigrovic PA, Ombrello MJ, Rabinovich CE, Tesher M, Twilt M, Klein-Gitelman M, Barbar-Smiley F, Cooper AM, Edelheit B, Gillispie-Taylor M, Hays K, Mannion ML, Peterson R, Flanagan E, Saad N, Sullivan N, Szymanski AM, Trachtman R, Turgunbaev M, Veiga K, Turner AS, Reston JT. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Oligoarthritis, Temporomandibular Joint Arthritis, and Systemic Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2022 04; 74(4):521-537. PMID: 35233986.
    Citations: 1     Fields:    Translation:Humans
  14. Onel KB, Horton DB, Lovell DJ, Shenoi S, Cuello CA, Angeles-Han ST, Becker ML, Cron RQ, Feldman BM, Ferguson PJ, Gewanter H, Guzman J, Kimura Y, Lee T, Murphy K, Nigrovic PA, Ombrello MJ, Rabinovich CE, Tesher M, Twilt M, Klein-Gitelman M, Barbar-Smiley F, Cooper AM, Edelheit B, Gillispie-Taylor M, Hays K, Mannion ML, Peterson R, Flanagan E, Saad N, Sullivan N, Szymanski AM, Trachtman R, Turgunbaev M, Veiga K, Turner AS, Reston JT. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging. Arthritis Care Res (Hoboken). 2022 04; 74(4):505-520. PMID: 35233989.
    Citations:    Fields:    Translation:HumansPHPublic Health
  15. Onel KB, Horton DB, Lovell DJ, Shenoi S, Cuello CA, Angeles-Han ST, Becker ML, Cron RQ, Feldman BM, Ferguson PJ, Gewanter H, Guzman J, Kimura Y, Lee T, Murphy K, Nigrovic PA, Ombrello MJ, Rabinovich CE, Tesher M, Twilt M, Klein-Gitelman M, Barbar-Smiley F, Cooper AM, Edelheit B, Gillispie-Taylor M, Hays K, Mannion ML, Peterson R, Flanagan E, Saad N, Sullivan N, Szymanski AM, Trachtman R, Turgunbaev M, Veiga K, Turner AS, Reston JT. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Recommendations for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging. Arthritis Rheumatol. 2022 04; 74(4):570-585. PMID: 35233961.
    Citations:    Fields:    Translation:HumansPHPublic Health
  16. Onel KB, Horton DB, Lovell DJ, Shenoi S, Cuello CA, Angeles-Han ST, Becker ML, Cron RQ, Feldman BM, Ferguson PJ, Gewanter H, Guzman J, Kimura Y, Lee T, Murphy K, Nigrovic PA, Ombrello MJ, Rabinovich CE, Tesher M, Twilt M, Klein-Gitelman M, Barbar-Smiley F, Cooper AM, Edelheit B, Gillispie-Taylor M, Hays K, Mannion ML, Peterson R, Flanagan E, Saad N, Sullivan N, Szymanski AM, Trachtman R, Turgunbaev M, Veiga K, Turner AS, Reston JT. 2021 American College of Rheumatology Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Oligoarthritis, Temporomandibular Joint Arthritis, and Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2022 04; 74(4):553-569. PMID: 35233993.
    Citations:    Fields:    Translation:Humans
  17. Grieshaber-Bouyer R, Exner T, Hackert NS, Radtke FA, Jelinsky SA, Halyabar O, Wactor A, Karimizadeh E, Brennan J, Schettini J, Jonsson H, Rao DA, Henderson LA, Müller-Tidow C, Lorenz HM, Wabnitz G, Lederer JA, Hadjipanayis A, Nigrovic PA. Ageing and interferon gamma response drive the phenotype of neutrophils in the inflamed joint. Ann Rheum Dis. 2022 06; 81(6):805-814. PMID: 35168946; PMCID: PMC9380120.
    Citations:    Fields:    Translation:HumansAnimalsCells
  18. Van Der Heijden H, Fatou B, Sibai D, Hoyt K, Taylor M, Cheung K, Lemme J, Cay M, Goodlett B, Lo J, Hazen MM, Halyabar O, Meidan E, Schreiber R, Jaimes C, Ecklund K, Henderson LA, Chang MH, Nigrovic PA, Sundel RP, Steen H, Upadhyay J. Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis. Pediatr Rheumatol Online J. 2022 Jan 15; 20(1):3. PMID: 35033099; PMCID: PMC8761318.
    Citations:    Fields:    Translation:Humans
  19. Roberts JE, Nigrovic PA, Lo MS, Chang MH. Weekly Adalimumab, an Effective Alternative for Refractory Uveitis in Children. J Clin Rheumatol. 2022 Jan 01; 28(1):e301-e304. PMID: 33790207.
    Citations:    Fields:    Translation:Humans
  20. Chang MH, Levescot A, Nelson-Maney N, Blaustein RB, Winden KD, Morris A, Wactor A, Balu S, Grieshaber-Bouyer R, Wei K, Henderson LA, Iwakura Y, Clark RA, Rao DA, Fuhlbrigge RC, Nigrovic PA. Arthritis flares mediated by tissue-resident memory T cells in the joint. Cell Rep. 2021 10 26; 37(4):109902. PMID: 34706228; PMCID: PMC8561718.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  21. Julé AM, Hoyt KJ, Wei K, Gutierrez-Arcelus M, Taylor ML, Ng J, Lederer JA, Case SM, Chang MH, Cohen EM, Dedeoglu F, Hazen MM, Hausmann JS, Halyabar O, Janssen E, Lo J, Lo MS, Meidan E, Roberts JE, Son MBF, Sundel RP, Lee PY, Chatila T, Nigrovic PA, Henderson LA. Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. JCI Insight. 2021 09 22; 6(18). PMID: 34403374; PMCID: PMC8492302.
    Citations: 1     Fields:    Translation:HumansCells
  22. Levescot A, Chang MH, Schnell J, Nelson-Maney N, Yan J, Martínez-Bonet M, Grieshaber-Bouyer R, Lee PY, Wei K, Blaustein RB, Morris A, Wactor A, Iwakura Y, Lederer JA, Rao DA, Charles JF, Nigrovic PA. IL-1ß-driven osteoclastogenic Tregs accelerate bone erosion in arthritis. J Clin Invest. 2021 09 15; 131(18). PMID: 34343136.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  23. Radtke FA, Ramadoss N, Garro A, Bennett JE, Levas MN, Robinson WH, Nigrovic PA, Nigrovic LE. Serologic Response to Borrelia Antigens Varies with Clinical Phenotype in Children and Young Adults with Lyme Disease. J Clin Microbiol. 2021 10 19; 59(11):e0134421. PMID: 34379528; PMCID: PMC8525570.
    Citations:    Fields:    Translation:HumansCells
  24. Baglaenko Y, Macfarlane D, Marson A, Nigrovic PA, Raychaudhuri S. Genome editing to define the function of risk loci and variants in rheumatic disease. Nat Rev Rheumatol. 2021 08; 17(8):462-474. PMID: 34188205.
    Citations: 1     Fields:    Translation:HumansAnimals
  25. Upadhyay J, Lemme J, Cay M, Van Der Heijden H, Sibai D, Goodlett B, Lo J, Hoyt K, Taylor M, Hazen MM, Halyabar O, Meidan E, Schreiber R, Chang MH, Nigrovic PA, Jaimes C, Henderson LA, Ecklund K, Sundel RP. A multidisciplinary assessment of pain in juvenile idiopathic arthritis. Semin Arthritis Rheum. 2021 08; 51(4):700-711. PMID: 34139523; PMCID: PMC9741862.
    Citations: 3     Fields:    Translation:Humans
  26. Mijakovac A, Juric J, Kohrt WM, Krištic J, Kifer D, Gavin KM, Miškec K, Frkatovic A, Vuckovic F, Pezer M, Vojta A, Nigrovic PA, Zoldoš V, Lauc G. Effects of Estradiol on Immunoglobulin G Glycosylation: Mapping of the Downstream Signaling Mechanism. Front Immunol. 2021; 12:680227. PMID: 34113353; PMCID: PMC8186398.
    Citations: 1     Fields:    Translation:HumansCells
  27. Cheung P, Schaffert S, Chang SE, Dvorak M, Donato M, Macaubas C, Foecke MH, Li TM, Zhang L, Coan JP, Schulert GS, Grom AA, Henderson LA, Nigrovic PA, Elias JE, Gozani O, Mellins ED, Khatri P, Utz PJ, Kuo AJ. Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation. Nat Immunol. 2021 06; 22(6):711-722. PMID: 34017121.
    Citations: 4     Fields:    Translation:HumansCells
  28. Grieshaber-Bouyer R, Radtke FA, Cunin P, Stifano G, Levescot A, Vijaykumar B, Nelson-Maney N, Blaustein RB, Monach PA, Nigrovic PA. The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments. Nat Commun. 2021 05 17; 12(1):2856. PMID: 34001893; PMCID: PMC8129206.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  29. Jee H, Huang Z, Baxter S, Huang Y, Taylor ML, Henderson LA, Rosenzweig S, Sharma A, Chambers EP, Hershfield MS, Zhou Q, Dedeoglu F, Aksentijevich I, Nigrovic PA, O'Donnell-Luria A, Lee PY. Comprehensive analysis of ADA2 genetic variants and estimation of carrier frequency driven by a function-based approach. J Allergy Clin Immunol. 2022 01; 149(1):379-387. PMID: 34004258; PMCID: PMC8591146.
    Citations: 2     Fields:    Translation:HumansCells
  30. Nigrovic PA, Colbert RA, Holers VM, Ozen S, Ruperto N, Thompson SD, Wedderburn LR, Yeung RSM, Martini A. Publisher Correction: Biological classification of childhood arthritis: roadmap to a molecular nomenclature. Nat Rev Rheumatol. 2021 May; 17(5):306. PMID: 33782593.
    Citations:    Fields:    
  31. Solomon DH, Binstadt BA, Felson DT, Nigrovic PA. A Picture Is Worth a Thousand Words, But Only If It Is a Good Picture. Arthritis Rheumatol. 2021 06; 73(6):912-913. PMID: 33559356.
    Citations:    Fields:    Translation:Humans
  32. Nigrovic PA, Colbert RA, Holers VM, Ozen S, Ruperto N, Thompson SD, Wedderburn LR, Yeung RSM, Martini A. Biological classification of childhood arthritis: roadmap to a molecular nomenclature. Nat Rev Rheumatol. 2021 05; 17(5):257-269. PMID: 33731872.
    Citations: 9     Fields:    Translation:Humans
  33. Ptacek J, Hawtin RE, Sun D, Louie B, Evensen E, Mittleman BB, Cesano A, Cavet G, Bingham CO, Cofield SS, Curtis JR, Danila MI, Raman C, Furie RA, Genovese MC, Robinson WH, Levesque MC, Moreland LW, Nigrovic PA, Shadick NA, O'Dell JR, Thiele GM, Clair EWS, Striebich CC, Hale MB, Khalili H, Batliwalla F, Aranow C, Mackay M, Diamond B, Nolan GP, Gregersen PK, Bridges SL. Diminished cytokine-induced Jak/STAT signaling is associated with rheumatoid arthritis and disease activity. PLoS One. 2021; 16(1):e0244187. PMID: 33444321.
    Citations: 4     Fields:    Translation:HumansCells
  34. Lagattuta KA, Nigrovic PA. Estrogen-Driven Changes in Immunoglobulin G Fc Glycosylation. Exp Suppl. 2021; 112:341-361. PMID: 34687016.
    Citations: 2     Fields:    Translation:HumansCells
  35. Wu FM, Valente AM, Nigrovic PA, Rutherford AE, Singh MN. Intraperitoneal corticosteroids for recurrent ascites in patients with Fontan circulation: Initial clinical experience. J Card Surg. 2021 Feb; 36(2):735-738. PMID: 33305839.
    Citations:    Fields:    Translation:Humans
  36. Nigrovic PA. COVID-19 cytokine storm: what is in a name? Ann Rheum Dis. 2021 01; 80(1):3-5. PMID: 33203641.
    Citations: 9     Fields:    Translation:HumansCells
  37. Han S, Zhuang H, Li M, Yang L, Lee PY, Nigrovic PA, Reeves WH. Reply. Arthritis Rheumatol. 2021 01; 73(1):176-178. PMID: 32776428.
    Citations:    Fields:    Translation:Cells
  38. Lee PY, Day-Lewis M, Henderson LA, Friedman KG, Lo J, Roberts JE, Lo MS, Platt CD, Chou J, Hoyt KJ, Baker AL, Banzon TM, Chang MH, Cohen E, de Ferranti SD, Dionne A, Habiballah S, Halyabar O, Hausmann JS, Hazen MM, Janssen E, Meidan E, Nelson RW, Nguyen AA, Sundel RP, Dedeoglu F, Nigrovic PA, Newburger JW, Son MBF. Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children. J Clin Invest. 2020 11 02; 130(11):5942-5950. PMID: 32701511; PMCID: PMC7598077.
    Citations: 115     Fields:    Translation:HumansCells
  39. Nigrovic PA, Lee PY, Hoffman HM. Monogenic autoinflammatory disorders: Conceptual overview, phenotype, and clinical approach. J Allergy Clin Immunol. 2020 11; 146(5):925-937. PMID: 33160483; PMCID: PMC7727443.
    Citations: 20     Fields:    Translation:HumansAnimals
  40. Juric J, Kohrt WM, Kifer D, Gavin KM, Pezer M, Nigrovic PA, Lauc G. Effects of estradiol on biological age measured using the glycan age index. Aging (Albany NY). 2020 Oct 13; 12(19):19756-19765. PMID: 33049709; PMCID: PMC7732334.
    Citations: 3     Fields:    
  41. Solomon DH, Bucala R, Kaplan MJ, Nigrovic PA. The "Infodemic" of COVID-19. Arthritis Rheumatol. 2020 11; 72(11):1806-1808. PMID: 32741134; PMCID: PMC7435516.
    Citations: 9     Fields:    Translation:Humans
  42. Han S, Zhuang H, Lee PY, Li M, Yang L, Nigrovic PA, Reeves WH. NF-E2-Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus. Arthritis Rheumatol. 2020 10; 72(10):1707-1720. PMID: 32500632; PMCID: PMC7718430.
    Citations: 5     Fields:    Translation:AnimalsCells
  43. Solomon DH, Bucala RJ, Kaplan MJ, Nigrovic PA. Arthritis & Rheumatology: Evolving to Meet the Challenges of Rheumatology. Arthritis Rheumatol. 2020 08; 72(8):1254-1255. PMID: 32510797.
    Citations:    Fields:    Translation:Humans
  44. Paranjape A, Haque TT, Kiwanuka KN, Qayum AA, Barnstein BO, Finkelman FD, Nigrovic PA, Ryan JJ. The Fyn-Stat5 cascade is required for Fc? receptor-mediated mast cell function. Cell Immunol. 2020 10; 356:104134. PMID: 32862025.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  45. Stoll ML, Duck LW, Chang MH, Colbert RA, Nigrovic PA, Thompson SD, Elson CO. Identification of Prevotella Oralis as a possible target antigen in children with Enthesitis related arthritis. Clin Immunol. 2020 07; 216:108463. PMID: 32437923.
    Citations:    Fields:    Translation:HumansCells
  46. Henderson LA, Canna SW, Schulert GS, Volpi S, Lee PY, Kernan KF, Caricchio R, Mahmud S, Hazen MM, Halyabar O, Hoyt KJ, Han J, Grom AA, Gattorno M, Ravelli A, De Benedetti F, Behrens EM, Cron RQ, Nigrovic PA. On the Alert for Cytokine Storm: Immunopathology in COVID-19. Arthritis Rheumatol. 2020 07; 72(7):1059-1063. PMID: 32293098; PMCID: PMC7262347.
    Citations: 273     Fields:    Translation:HumansCellsPHPublic Health
  47. Huang Z, Li T, Nigrovic PA, Lee PY. Polyarteritis nodosa and deficiency of adenosine deaminase 2 - Shared genealogy, generations apart. Clin Immunol. 2020 06; 215:108411. PMID: 32276138.
    Citations: 3     Fields:    Translation:Humans
  48. Henderson LA, Hoyt KJ, Lee PY, Rao DA, Jonsson AH, Nguyen JP, Rutherford K, Julé AM, Charbonnier LM, Case S, Chang MH, Cohen EM, Dedeoglu F, Fuhlbrigge RC, Halyabar O, Hazen MM, Janssen E, Kim S, Lo J, Lo MS, Meidan E, Son MBF, Sundel RP, Stoll ML, Nusbaum C, Lederer JA, Chatila TA, Nigrovic PA. Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. JCI Insight. 2020 03 26; 5(6). PMID: 32213704.
    Citations: 12     Fields:    Translation:HumansCells
  49. Schmider AB, Bauer NC, Sunwoo H, Godin MD, Ellis GE, Lee JT, Nigrovic PA, Soberman RJ. Two- and three-color STORM analysis reveals higher-order assembly of leukotriene synthetic complexes on the nuclear envelope of murine neutrophils. J Biol Chem. 2020 04 24; 295(17):5761-5770. PMID: 32152223.
    Citations:    Fields:    Translation:AnimalsCells
  50. Lee PY, Huang Z, Hershfield MS, Nigrovic PA. Response to: 'Total adenosine deaminase highly correlated with adenosine deaminase 2 activity in serum' by Gao et al. Ann Rheum Dis. 2022 02; 81(2):e31. PMID: 32054602.
    Citations: 3     Fields:    Translation:Humans
  51. Lee PY, Kellner ES, Huang Y, Furutani E, Huang Z, Bainter W, Alosaimi MF, Stafstrom K, Platt CD, Stauber T, Raz S, Tirosh I, Weiss A, Jordan MB, Krupski C, Eleftheriou D, Brogan P, Sobh A, Baz Z, Lefranc G, Irani C, Kilic SS, El-Owaidy R, Lokeshwar MR, Pimpale P, Khubchandani R, Chambers EP, Chou J, Geha RS, Nigrovic PA, Zhou Q. Genotype and functional correlates of disease phenotype in deficiency of adenosine deaminase 2 (DADA2). J Allergy Clin Immunol. 2020 06; 145(6):1664-1672.e10. PMID: 31945408; PMCID: PMC7282972.
    Citations: 29     Fields:    Translation:Humans
  52. Han S, Zhuang H, Lee PY, Li M, Yang L, Nigrovic PA, Reeves WH. Differential Responsiveness of Monocyte and Macrophage Subsets to Interferon. Arthritis Rheumatol. 2020 01; 72(1):100-113. PMID: 31390156; PMCID: PMC6935410.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  53. Cunin P, Nigrovic PA. Megakaryocyte emperipolesis: a new frontier in cell-in-cell interaction. Platelets. 2020 Aug 17; 31(6):700-706. PMID: 31752579.
    Citations: 8     Fields:    Translation:HumansCells
  54. Lee PY, Schulert GS, Canna SW, Huang Y, Sundel J, Li Y, Hoyt KJ, Blaustein RB, Wactor A, Do T, Halyabar O, Chang MH, Dedeoglu F, Case SM, Meidan E, Lo MS, Sundel RP, Richardson ET, Newburger JW, Hershfield MS, Son MB, Henderson LA, Nigrovic PA. Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis. Ann Rheum Dis. 2020 02; 79(2):225-231. PMID: 31707357; PMCID: PMC7385992.
    Citations: 18     Fields:    Translation:Humans
  55. Cheng HD, Tirosh I, de Haan N, Stöckmann H, Adamczyk B, McManus CA, O'Flaherty R, Greville G, Saldova R, Bonilla FA, Notarangelo LD, Driessen GJ, Holm IA, Rudd PM, Wuhrer M, Ackerman ME, Nigrovic PA. IgG Fc glycosylation as an axis of humoral immunity in childhood. J Allergy Clin Immunol. 2020 02; 145(2):710-713.e9. PMID: 31669096; PMCID: PMC7010538.
    Citations: 11     Fields:    Translation:HumansCells
  56. Bocharnikov AV, Keegan J, Wacleche VS, Cao Y, Fonseka CY, Wang G, Muise ES, Zhang KX, Arazi A, Keras G, Li ZJ, Qu Y, Gurish MF, Petri M, Buyon JP, Putterman C, Wofsy D, James JA, Guthridge JM, Diamond B, Anolik JH, Mackey MF, Alves SE, Nigrovic PA, Costenbader KH, Brenner MB, Lederer JA, Rao DA. PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21. JCI Insight. 2019 10 17; 4(20). PMID: 31536480; PMCID: PMC6824311.
    Citations: 51     Fields:    Translation:HumansCells
  57. Hou L, Rao DA, Yuki K, Cooley J, Henderson LA, Jonsson AH, Kaiserman D, Gorman MP, Nigrovic PA, Bird PI, Becher B, Remold-O'Donnell E. SerpinB1 controls encephalitogenic T helper cells in neuroinflammation. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20635-20643. PMID: 31548399; PMCID: PMC6789640.
    Citations: 7     Fields:    Translation:AnimalsCells
  58. Nigrovic PA. Storm Warning: Lung Disease in Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2019 11; 71(11):1773-1775. PMID: 31390168; PMCID: PMC6817387.
    Citations: 2     Fields:    Translation:Humans
  59. Nigrovic PA, Martínez-Bonet M, Thompson SD. Implications of juvenile idiopathic arthritis genetic risk variants for disease pathogenesis and classification. Curr Opin Rheumatol. 2019 09; 31(5):401-410. PMID: 31169548.
    Citations: 7     Fields:    Translation:Humans
  60. Luo Y, Suliman S, Asgari S, Amariuta T, Baglaenko Y, Martínez-Bonet M, Ishigaki K, Gutierrez-Arcelus M, Calderon R, Lecca L, León SR, Jimenez J, Yataco R, Contreras C, Galea JT, Becerra M, Nejentsev S, Nigrovic PA, Moody DB, Murray MB, Raychaudhuri S. Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians. Nat Commun. 2019 08 21; 10(1):3765. PMID: 31434886.
    Citations: 17     Fields:    Translation:HumansCells
  61. Lee PY, Nelson-Maney N, Huang Y, Levescot A, Wang Q, Wei K, Cunin P, Li Y, Lederer JA, Zhuang H, Han S, Kim EY, Reeves WH, Nigrovic PA. High-dimensional analysis reveals a pathogenic role of inflammatory monocytes in experimental diffuse alveolar hemorrhage. JCI Insight. 2019 08 08; 4(15). PMID: 31391335.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  62. Chan TY, Yen CL, Huang YF, Lo PC, Nigrovic PA, Cheng CY, Wang WZ, Wu SY, Shieh CC. Increased ILC3s associated with higher levels of IL-1ß aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase. Eur J Immunol. 2019 11; 49(11):2063-2073. PMID: 31350760.
    Citations: 3     Fields:    Translation:AnimalsCells
  63. Urso K, Caetano-Lopes J, Lee PY, Yan J, Henke K, Sury M, Liu H, Zgoda M, Jacome-Galarza C, Nigrovic PA, Duryea J, Harris MP, Charles JF. A role for G protein-coupled receptor 137b in bone remodeling in mouse and zebrafish. Bone. 2019 10; 127:104-113. PMID: 31173907.
    Citations: 3     Fields:    Translation:AnimalsCells
  64. Fang C, Manes TD, Liu L, Liu K, Qin L, Li G, Tobiasova Z, Kirkiles-Smith NC, Patel M, Merola J, Fu W, Liu R, Xie C, Tietjen GT, Nigrovic PA, Tellides G, Pober JS, Jane-Wit D. ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-?B via phosphoinosotide remodeling of endosomes. Nat Commun. 2019 05 21; 10(1):2247. PMID: 31113953.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  65. Cunin P, Bouslama R, Machlus KR, Martínez-Bonet M, Lee PY, Wactor A, Nelson-Maney N, Morris A, Guo L, Weyrich A, Sola-Visner M, Boilard E, Italiano JE, Nigrovic PA. Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets. Elife. 2019 05 01; 8. PMID: 31042146.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  66. Ringold S, Angeles-Han ST, Beukelman T, Lovell D, Cuello CA, Becker ML, Colbert RA, Feldman BM, Ferguson PJ, Gewanter H, Guzman J, Horonjeff J, Nigrovic PA, Ombrello MJ, Passo MH, Stoll ML, Rabinovich CE, Schneider R, Halyabar O, Hays K, Shah AA, Sullivan N, Szymanski AM, Turgunbaev M, Turner A, Reston J. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis. Arthritis Rheumatol. 2019 06; 71(6):846-863. PMID: 31021537; PMCID: PMC6561114.
    Citations: 25     Fields:    Translation:Humans
  67. Angeles-Han ST, Ringold S, Beukelman T, Lovell D, Cuello CA, Becker ML, Colbert RA, Feldman BM, Holland GN, Ferguson PJ, Gewanter H, Guzman J, Horonjeff J, Nigrovic PA, Ombrello MJ, Passo MH, Stoll ML, Rabinovich CE, Sen HN, Schneider R, Halyabar O, Hays K, Shah AA, Sullivan N, Szymanski AM, Turgunbaev M, Turner A, Reston J. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis. Arthritis Rheumatol. 2019 06; 71(6):864-877. PMID: 31021511; PMCID: PMC6788287.
    Citations: 12     Fields:    Translation:HumansPHPublic Health
  68. Ringold S, Angeles-Han ST, Beukelman T, Lovell D, Cuello CA, Becker ML, Colbert RA, Feldman BM, Ferguson PJ, Gewanter H, Guzman J, Horonjeff J, Nigrovic PA, Ombrello MJ, Passo MH, Stoll ML, Rabinovich CE, Schneider R, Halyabar O, Hays K, Shah AA, Sullivan N, Szymanski AM, Turgunbaev M, Turner A, Reston J. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non-Systemic Polyarthritis, Sacroiliitis, and Enthesitis. Arthritis Care Res (Hoboken). 2019 06; 71(6):717-734. PMID: 31021516.
    Citations: 29     Fields:    Translation:Humans
  69. Angeles-Han ST, Ringold S, Beukelman T, Lovell D, Cuello CA, Becker ML, Colbert RA, Feldman BM, Holland GN, Ferguson PJ, Gewanter H, Guzman J, Horonjeff J, Nigrovic PA, Ombrello MJ, Passo MH, Stoll ML, Rabinovich CE, Sen HN, Schneider R, Halyabar O, Hays K, Shah AA, Sullivan N, Szymanski AM, Turgunbaev M, Turner A, Reston J. 2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis. Arthritis Care Res (Hoboken). 2019 06; 71(6):703-716. PMID: 31021540.
    Citations: 33     Fields:    Translation:Humans
  70. Chang MH, Nigrovic PA. Antibody-dependent and -independent mechanisms of inflammatory arthritis. JCI Insight. 2019 03 07; 4(5). PMID: 30843881.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  71. Grieshaber-Bouyer R, Nigrovic PA. Neutrophil Heterogeneity as Therapeutic Opportunity in Immune-Mediated Disease. Front Immunol. 2019; 10:346. PMID: 30886615; PMCID: PMC6409342.
    Citations: 31     Fields:    Translation:HumansCells
  72. Halyabar O, Chang MH, Schoettler ML, Schwartz MA, Baris EH, Benson LA, Biggs CM, Gorman M, Lehmann L, Lo MS, Nigrovic PA, Platt CD, Priebe GP, Rowe J, Sundel RP, Surana NK, Weinacht KG, Mann A, Yuen JC, Meleedy-Rey P, Starmer A, Banerjee T, Dedeoglu F, Degar BA, Hazen MM, Henderson LA. Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome. Pediatr Rheumatol Online J. 2019 Feb 14; 17(1):7. PMID: 30764840.
    Citations: 25     Fields:    Translation:Humans
  73. Cunin P, Lee PY, Kim E, Schmider AB, Cloutier N, Pare A, Gunzer M, Soberman RJ, Lacroix S, Boilard E, Lefort CT, Nigrovic PA. Differential attenuation of ß2 integrin-dependent and -independent neutrophil migration by Ly6G ligation. Blood Adv. 2019 02 12; 3(3):256-267. PMID: 30696624; PMCID: PMC6373735.
    Citations: 6     Fields:    Translation:AnimalsCells
  74. Schmider AB, Vaught M, Bauer NC, Elliott HL, Godin MD, Ellis GE, Nigrovic PA, Soberman RJ. The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses. PLoS One. 2019; 14(2):e0211943. PMID: 30735559; PMCID: PMC6368329.
    Citations: 5     Fields:    Translation:AnimalsCells
  75. Beukelman T, Nigrovic PA. Juvenile Idiopathic Arthritis: An Idea Whose Time Has Gone? J Rheumatol. 2019 02; 46(2):124-126. PMID: 30710000.
    Citations: 4     Fields:    Translation:Humans
  76. Cunin P, Nigrovic PA. Megakaryocytes as immune cells. J Leukoc Biol. 2019 06; 105(6):1111-1121. PMID: 30645026.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  77. Grieshaber-Bouyer R, Nigrovic PA. Maestro endothelium conducts the neutrophils. Blood. 2018 10 25; 132(17):1734-1735. PMID: 30361462; PMCID: PMC6202913.
    Citations:    Fields:    Translation:Cells
  78. Westra HJ, Martínez-Bonet M, Onengut-Gumuscu S, Lee A, Luo Y, Teslovich N, Worthington J, Martin J, Huizinga T, Klareskog L, Rantapaa-Dahlqvist S, Chen WM, Quinlan A, Todd JA, Eyre S, Nigrovic PA, Gregersen PK, Rich SS, Raychaudhuri S. Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. Nat Genet. 2018 10; 50(10):1366-1374. PMID: 30224649; PMCID: PMC6364548.
    Citations: 53     Fields:    Translation:HumansCells
  79. Li G, Martínez-Bonet M, Wu D, Yang Y, Cui J, Nguyen HN, Cunin P, Levescot A, Bai M, Westra HJ, Okada Y, Brenner MB, Raychaudhuri S, Hendrickson EA, Maas RL, Nigrovic PA. High-throughput identification of noncoding functional SNPs via type IIS enzyme restriction. Nat Genet. 2018 08; 50(8):1180-1188. PMID: 30013183.
    Citations: 13     Fields:    Translation:HumansCells
  80. Vastert SJ, Nigrovic PA. Editorial: Toward Personalized Treatment for Systemic Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2018 08; 70(8):1172-1174. PMID: 29569852; PMCID: PMC6105394.
    Citations: 1     Fields:    Translation:Humans
  81. Lee PY, Huang Y, Zhou Q, Schnappauf O, Hershfield MS, Li Y, Ganson NJ, Sampaio Moura N, Delmonte OM, Stone SS, Rivkin MJ, Pai SY, Lyons T, Sundel RP, Hsu VW, Notarangelo LD, Aksentijevich I, Nigrovic PA. Disrupted N-linked glycosylation as a disease mechanism in deficiency of ADA2. J Allergy Clin Immunol. 2018 10; 142(4):1363-1365.e8. PMID: 29936104; PMCID: PMC6175612.
    Citations: 15     Fields:    Translation:HumansCells
  82. Dart AH, Michelson KA, Aronson PL, Garro AC, Lee TJ, Glerum KM, Nigrovic PA, Kocher MS, Bachur RG, Nigrovic LE. Hip Synovial Fluid Cell Counts in Children From a Lyme Disease Endemic Area. Pediatrics. 2018 05; 141(5). PMID: 29669751; PMCID: PMC5914490.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  83. Ringold S, Nigrovic PA, Feldman BM, Tomlinson GA, von Scheven E, Wallace CA, Huber AM, Schanberg LE, Li SC, Weiss PF, Fuhlbrigge RC, Morgan EM, Kimura Y. The Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans: Toward Comparative Effectiveness in the Pediatric Rheumatic Diseases. Arthritis Rheumatol. 2018 05; 70(5):669-678. PMID: 29333701.
    Citations: 10     Fields:    Translation:Humans
  84. Nigrovic PA, Beukelman T, Tomlinson G, Feldman BM, Schanberg LE, Kimura Y. Bayesian comparative effectiveness study of four consensus treatment plans for initial management of systemic juvenile idiopathic arthritis: FiRst-Line Options for Systemic juvenile idiopathic arthritis Treatment (FROST). Clin Trials. 2018 06; 15(3):268-277. PMID: 29542334.
    Citations: 4     Fields:    Translation:Humans
  85. Mizoguchi F, Slowikowski K, Wei K, Marshall JL, Rao DA, Chang SK, Nguyen HN, Noss EH, Turner JD, Earp BE, Blazar PE, Wright J, Simmons BP, Donlin LT, Kalliolias GD, Goodman SM, Bykerk VP, Ivashkiv LB, Lederer JA, Hacohen N, Nigrovic PA, Filer A, Buckley CD, Raychaudhuri S, Brenner MB. Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis. Nat Commun. 2018 02 23; 9(1):789. PMID: 29476097.
    Citations: 160     Fields:    Translation:HumansCells
  86. Ogdie A, Sparks JA, Angeles-Han ST, Bush K, Castelino FV, Golding A, Jiang Y, Kahlenberg JM, Kim AHJ, Lee YC, Machireddy K, Ombrello MJ, Shah AA, Wallace ZS, Nigrovic PA, Makris UE. Barriers and Facilitators of Mentoring for Trainees and Early Career Investigators in Rheumatology Research: Current State, Identification of Needs, and Road Map to an Inter-Institutional Adult Rheumatology Mentoring Program. Arthritis Care Res (Hoboken). 2018 03; 70(3):445-453. PMID: 28544766.
    Citations: 5     Fields:    Translation:Humans
  87. Stoll ML, Weiss PF, Weiss JE, Nigrovic PA, Edelheit BS, Bridges SL, Danila MI, Spencer CH, Punaro MG, Schikler K, Reiff A, Kumar R, Cron RQ, Morrow CD, Lefkowitz EJ. Age and fecal microbial strain-specific differences in patients with spondyloarthritis. Arthritis Res Ther. 2018 01 30; 20(1):14. PMID: 29382366; PMCID: PMC5791354.
    Citations: 20     Fields:    Translation:HumansCells
  88. Schulert GS, Minoia F, Bohnsack J, Cron RQ, Hashad S, KonÉ-Paut I, Kostik M, Lovell D, Maritsi D, Nigrovic PA, Pal P, Ravelli A, Shimizu M, Stanevicha V, Vastert S, Woerner A, de Benedetti F, Grom AA. Effect of Biologic Therapy on Clinical and Laboratory Features of Macrophage Activation Syndrome Associated With Systemic Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2018 03; 70(3):409-419. PMID: 28499329.
    Citations: 29     Fields:    Translation:Humans
  89. Chao WC, Yen CL, Hsieh CY, Huang YF, Tseng YL, Nigrovic PA, Shieh CC. Mycobacterial infection induces higher interleukin-1ß and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase. PLoS One. 2017; 12(12):e0189453. PMID: 29228045.
    Citations: 9     Fields:    Translation:AnimalsCells
  90. Nigrovic PA, Raychaudhuri S, Thompson SD. Review: Genetics and the Classification of Arthritis in Adults and Children. Arthritis Rheumatol. 2018 01; 70(1):7-17. PMID: 29024575; PMCID: PMC5805142.
    Citations: 48     Fields:    Translation:Humans
  91. Cheng HD, Stöckmann H, Adamczyk B, McManus CA, Ercan A, Holm IA, Rudd PM, Ackerman ME, Nigrovic PA. High-throughput characterization of the functional impact of IgG Fc glycan aberrancy in juvenile idiopathic arthritis. Glycobiology. 2017 12 01; 27(12):1099-1108. PMID: 28973482.
    Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
  92. McIntosh LA, Marion MC, Sudman M, Comeau ME, Becker ML, Bohnsack JF, Fingerlin TE, Griffin TA, Haas JP, Lovell DJ, Maier LA, Nigrovic PA, Prahalad S, Punaro M, Rosé CD, Wallace CA, Wise CA, Moncrieffe H, Howard TD, Langefeld CD, Thompson SD. Genome-Wide Association Meta-Analysis Reveals Novel Juvenile Idiopathic Arthritis Susceptibility Loci. Arthritis Rheumatol. 2017 11; 69(11):2222-2232. PMID: 28719732; PMCID: PMC5874801.
    Citations: 24     Fields:    Translation:Humans
  93. Moncrieffe H, Bennett MF, Tsoras M, Luyrink LK, Johnson AL, Xu H, Dare J, Becker ML, Prahalad S, Rosenkranz M, O'Neil KM, Nigrovic PA, Griffin TA, Lovell DJ, Grom AA, Medvedovic M, Thompson SD. Transcriptional profiles of JIA patient blood with subsequent poor response to methotrexate. Rheumatology (Oxford). 2017 09 01; 56(9):1542-1551. PMID: 28582527; PMCID: PMC5850489.
    Citations: 7     Fields:    Translation:HumansCells
  94. Bai M, Grieshaber-Bouyer R, Wang J, Schmider AB, Wilson ZS, Zeng L, Halyabar O, Godin MD, Nguyen HN, Levescot A, Cunin P, Lefort CT, Soberman RJ, Nigrovic PA. CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation. Blood. 2017 11 09; 130(19):2092-2100. PMID: 28807980; PMCID: PMC5680608.
    Citations: 42     Fields:    Translation:HumansCells
  95. Lee PY, Sykes DB, Ameri S, Kalaitzidis D, Charles JF, Nelson-Maney N, Wei K, Cunin P, Morris A, Cardona AE, Root DE, Scadden DT, Nigrovic PA. The metabolic regulator mTORC1 controls terminal myeloid differentiation. Sci Immunol. 2017 May 26; 2(11). PMID: 28763796; PMCID: PMC6953719.
    Citations: 10     Fields:    
  96. Kimura Y, Grevich S, Beukelman T, Morgan E, Nigrovic PA, Mieszkalski K, Graham TB, Ibarra M, Ilowite N, Klein-Gitelman M, Onel K, Prahalad S, Punaro M, Ringold S, Toib D, Van Mater H, Weiss JE, Weiss PF, Schanberg LE. Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans. Pediatr Rheumatol Online J. 2017 Apr 11; 15(1):23. PMID: 28399931.
    Citations: 13     Fields:    Translation:Humans
  97. Cunin P, Penke LR, Thon JN, Monach PA, Jones T, Chang MH, Chen MM, Melki I, Lacroix S, Iwakura Y, Ware J, Gurish MF, Italiano JE, Boilard E, Nigrovic PA. Megakaryocytes compensate for Kit insufficiency in murine arthritis. J Clin Invest. 2017 May 01; 127(5):1714-1724. PMID: 28375155; PMCID: PMC5409069.
    Citations: 13     Fields:    Translation:AnimalsCells
  98. Nigrovic PA. Building an ARC to Grant Success: The Aims Review Committee. Arthritis Care Res (Hoboken). 2017 04; 69(4):459-461. PMID: 27696715.
    Citations: 1     Fields:    Translation:Humans
  99. Ercan A, Kohrt WM, Cui J, Deane KD, Pezer M, Yu EW, Hausmann JS, Campbell H, Kaiser UB, Rudd PM, Lauc G, Wilson JF, Finkelstein JS, Nigrovic PA. Estrogens regulate glycosylation of IgG in women and men. JCI Insight. 2017 02 23; 2(4):e89703. PMID: 28239652.
    Citations: 45     Fields:    Translation:HumansCells
  100. Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Lee YC, Todd DJ, Bykerk VP, Goodman SM, Pernis AB, Ivashkiv LB, Karlson EW, Nigrovic PA, Filer A, Buckley CD, Lederer JA, Raychaudhuri S, Brenner MB. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017 02 01; 542(7639):110-114. PMID: 28150777.
    Citations: 286     Fields:    Translation:HumansCells
  101. Hinks A, Bowes J, Cobb J, Ainsworth HC, Marion MC, Comeau ME, Sudman M, Han B, Becker ML, Bohnsack JF, de Bakker PI, Haas JP, Hazen M, Lovell DJ, Nigrovic PA, Nordal E, Punnaro M, Rosenberg AM, Rygg M, Smith SL, Wise CA, Videm V, Wedderburn LR, Yarwood A, Yeung RS, Prahalad S, Langefeld CD, Raychaudhuri S, Thompson SD, Thomson W. Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases. Ann Rheum Dis. 2017 04; 76(4):765-772. PMID: 27998952; PMCID: PMC5530326.
    Citations: 29     Fields:    Translation:Humans
  102. Konig MF, Abusleme L, Reinholdt J, Palmer RJ, Teles RP, Sampson K, Rosen A, Nigrovic PA, Sokolove J, Giles JT, Moutsopoulos NM, Andrade F. Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis. Sci Transl Med. 2016 12 14; 8(369):369ra176. PMID: 27974664; PMCID: PMC5384717.
    Citations: 192     Fields:    Translation:HumansCells
  103. Resnick CM, Dang R, Henderson LA, Zander DA, Daniels KM, Nigrovic PA, Kaban LB. Frequency and Morbidity of Temporomandibular Joint Involvement in Adult Patients With a History of Juvenile Idiopathic Arthritis. J Oral Maxillofac Surg. 2017 Jun; 75(6):1191-1200. PMID: 28003132.
    Citations: 4     Fields:    Translation:Humans
  104. Resnick CM, Vakilian PM, Breen M, Zurakowski D, Caruso P, Henderson L, Nigrovic PA, Kaban LB, Peacock ZS. Quantifying Temporomandibular Joint Synovitis in Children With Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2016 12; 68(12):1795-1802. PMID: 27110936.
    Citations: 15     Fields:    Translation:Humans
  105. Marcoux G, Duchez AC, Cloutier N, Provost P, Nigrovic PA, Boilard E. Revealing the diversity of extracellular vesicles using high-dimensional flow cytometry analyses. Sci Rep. 2016 10 27; 6:35928. PMID: 27786276.
    Citations: 38     Fields:    Translation:HumansCells
  106. Li G, Cunin P, Wu D, Diogo D, Yang Y, Okada Y, Plenge RM, Nigrovic PA. The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1. PLoS Genet. 2016 09; 12(9):e1006292. PMID: 27626929.
    Citations: 12     Fields:    Translation:HumansCells
  107. Henderson LA, Volpi S, Frugoni F, Janssen E, Kim S, Sundel RP, Dedeoglu F, Lo MS, Hazen MM, Beth Son M, Mathieu R, Zurakowski D, Yu N, Lebedeva T, Fuhlbrigge RC, Walter JE, Nee Lee Y, Nigrovic PA, Notarangelo LD. Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2016 07; 68(7):1758-68. PMID: 26815131; PMCID: PMC5398095.
    Citations: 22     Fields:    Translation:HumansCells
  108. Moorthy LN, Muscal E, Riebschleger M, Klein-Gitelman M, Nigrovic LE, Horon JR, Rouster-Stevens K, Ferguson PJ, Eberhard BA, Brunner HI, Prahalad S, Schneider R, Nigrovic PA. Efficacy of an Interinstitutional Mentoring Program Within Pediatric Rheumatology. Arthritis Care Res (Hoboken). 2016 05; 68(5):645-51. PMID: 26414673; PMCID: PMC6786258.
    Citations: 4     Fields:    Translation:Humans
  109. Canna SW, Nigrovic PA. Editorial: 21st Century Storm Chasers: Defining Macrophage Activation Syndrome. Arthritis Rheumatol. 2016 Mar; 68(3):557-60. PMID: 26314501; PMCID: PMC6786256.
    Citations: 3     Fields:    Translation:Humans
  110. Konig MF, Giles JT, Nigrovic PA, Andrade F. Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis. Ann Rheum Dis. 2016 Nov; 75(11):2022-2028. PMID: 26865600.
    Citations: 28     Fields:    Translation:Humans
  111. Nigrovic PA. Autoinflammation and autoimmunity in systemic juvenile idiopathic arthritis. Proc Natl Acad Sci U S A. 2015 Dec 29; 112(52):15785-6. PMID: 26677874; PMCID: PMC4703029.
    Citations: 14     Fields:    Translation:Humans
  112. Wampler Muskardin T, Vashisht P, Dorschner JM, Jensen MA, Chrabot BS, Kern M, Curtis JR, Danila MI, Cofield SS, Shadick N, Nigrovic PA, St Clair EW, Bingham CO, Furie R, Robinson W, Genovese M, Striebich CC, O'Dell JR, Thiele GM, Moreland LW, Levesque M, Bridges SL, Gregersen PK, Niewold TB. Increased pretreatment serum IFN-ß/a ratio predicts non-response to tumour necrosis factor a inhibition in rheumatoid arthritis. Ann Rheum Dis. 2016 10; 75(10):1757-62. PMID: 26546586; PMCID: PMC4860184.
    Citations: 15     Fields:    Translation:Humans
  113. Redelinghuys P, Whitehead L, Augello A, Drummond RA, Levesque JM, Vautier S, Reid DM, Kerscher B, Taylor JA, Nigrovic PA, Wright J, Murray GI, Willment JA, Hocking LJ, Fernandes MJ, De Bari C, Mcinnes IB, Brown GD. MICL controls inflammation in rheumatoid arthritis. Ann Rheum Dis. 2016 07; 75(7):1386-91. PMID: 26275430; PMCID: PMC4941174.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  114. Huang YF, Lo PC, Yen CL, Nigrovic PA, Chao WC, Wang WZ, Hsu GC, Tsai YS, Shieh CC. Redox Regulation of Pro-IL-1ß Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice. Antioxid Redox Signal. 2015 Oct 20; 23(12):973-84. PMID: 25867281; PMCID: PMC4624247.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  115. Dellinger AL, Cunin P, Lee D, Kung AL, Brooks DB, Zhou Z, Nigrovic PA, Kepley CL. Inhibition of inflammatory arthritis using fullerene nanomaterials. PLoS One. 2015; 10(4):e0126290. PMID: 25879437.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  116. Tuttle KS, Vargas SO, Callahan MJ, Bae DS, Nigrovic PA. Enthesitis as a component of dactylitis in psoriatic juvenile idiopathic arthritis: histology of an established clinical entity. Pediatr Rheumatol Online J. 2015; 13:7. PMID: 25774101.
    Citations: 9     Fields:    Translation:HumansCells
  117. Rousseau M, Belleannee C, Duchez AC, Cloutier N, Levesque T, Jacques F, Perron J, Nigrovic PA, Dieude M, Hebert MJ, Gelb MH, Boilard E. Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment. PLoS One. 2015; 10(1):e0116812. PMID: 25587983.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  118. Nigrovic PA, Shin K. Evaluation of synovial mast cell functions in autoimmune arthritis. Methods Mol Biol. 2015; 1220:423-42. PMID: 25388266; PMCID: PMC6817810.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  119. Kimura Y, DeWitt EM, Beukelman T, Stoll ML, Nigrovic PA, Onel K, Prahalad S, Angeles-Han S, Schneider R. Adding canakinumab to the Childhood Arthritis and Rheumatology Research Alliance consensus treatment plans for systemic juvenile idiopathic arthritis: Comment on the article by DeWitt et al. Arthritis Care Res (Hoboken). 2014 Sep; 66(9):1430-1. PMID: 24719268.
    Citations: 8     Fields:    Translation:Humans
  120. Nigrovic PA. Reply: To PMID 24623686. Arthritis Rheumatol. 2014 Sep; 66(9):2645-6. PMID: 24839252.
    Citations:    Fields:    Translation:HumansAnimals
  121. Boudreau LH, Duchez AC, Cloutier N, Soulet D, Martin N, Bollinger J, Paré A, Rousseau M, Naika GS, Lévesque T, Laflamme C, Marcoux G, Lambeau G, Farndale RW, Pouliot M, Hamzeh-Cognasse H, Cognasse F, Garraud O, Nigrovic PA, Guderley H, Lacroix S, Thibault L, Semple JW, Gelb MH, Boilard E. Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation. Blood. 2014 Oct 02; 124(14):2173-83. PMID: 25082876; PMCID: PMC4260364.
    Citations: 184     Fields:    Translation:HumansAnimalsCells
  122. Boesch AW, Brown EP, Cheng HD, Ofori MO, Normandin E, Nigrovic PA, Alter G, Ackerman ME. Highly parallel characterization of IgG Fc binding interactions. MAbs. 2014 Jul-Aug; 6(4):915-27. PMID: 24927273.
    Citations: 39     Fields:    Translation:HumansCells
  123. Wang JX, Kaieda S, Ameri S, Fishgal N, Dwyer D, Dellinger A, Kepley CL, Gurish MF, Nigrovic PA. IL-33/ST2 axis promotes mast cell survival via BCLXL. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10281-6. PMID: 24982172.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  124. Nigrovic PA. Review: is there a window of opportunity for treatment of systemic juvenile idiopathic arthritis? Arthritis Rheumatol. 2014 Jun; 66(6):1405-13. PMID: 24623686.
    Citations: 49     Fields:    Translation:HumansAnimals
  125. Rouster-Stevens KA, Ardoin SP, Cooper AM, Becker ML, Dragone LL, Huttenlocher A, Jones KB, Kolba KS, Moorthy LN, Nigrovic PA, Stinson JN, Ferguson PJ. Choosing Wisely: the American College of Rheumatology's Top 5 for pediatric rheumatology. Arthritis Care Res (Hoboken). 2014 May; 66(5):649-57. PMID: 24756998.
    Citations: 3     Fields:    Translation:Humans
  126. Henderson LA, King SL, Ameri S, Martin SD, Simmons BP, Nigrovic PA, Fuhlbrigge RC. A161: Novel 3-Dimensional Explant Method Facilitates the Study of Lymphocyte Populations in the Synovium and Reveals a Large Population of Resident Memory T cells in Rheumatoid Arthritis. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S209. PMID: 24677916.
    Citations:    
  127. Henderson LA, Volpi S, Frugoni F, Kim S, Janssen E, Sundel RP, Dedeoglu F, Lo MS, Hazen MM, Mathieu R, Fuhlbrigge RC, Lee YN, Nigrovic PA, Notarangelo LD. A119: deep sequencing analysis of the T regulatory and T effector repertoire in juvenile idiopathic arthritis. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S156. PMID: 24677872.
    Citations:    
  128. Muscal E, Moorthy LN, Riebschleger MP, Eberhard A, Huttenlocher A, Klein-Gitelman MS, Prahalad S, Stevens KR, Schneider R, Nigrovic PA. A177: Program Evaluation of the ACR/CARRA Inter-Institutional Mentoring Program (AMIGO) in Pediatric Rheumatology. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S231. PMID: 24677934.
    Citations:    
  129. Nigrovic PA, Muscal E, Riebschleger M, Moorthy LN, Brunner HI, Eberhard BA, Klein-Gitelman M, Prahalad S, Schneider R. AMIGO: a novel approach to the mentorship gap in pediatric rheumatology. J Pediatr. 2014 Feb; 164(2):226-7.e1-3. PMID: 24461154; PMCID: PMC6786259.
    Citations: 7     Fields:    Translation:Humans
  130. Dauber A, Ercan A, Lee J, James P, Jacobs PP, Ashline DJ, Wang SR, Miller T, Hirschhorn JN, Nigrovic PA, Sackstein R. Congenital disorder of fucosylation type 2c (LADII) presenting with short stature and developmental delay with minimal adhesion defect. Hum Mol Genet. 2014 Jun 01; 23(11):2880-7. PMID: 24403049; PMCID: PMC4014190.
    Citations: 15     Fields:    Translation:HumansCells
  131. Fernandes SM, O'Sullivan-Oliveira J, Landzberg MJ, Khairy P, Melvin P, Sawicki GS, Ziniel S, Kenney LB, Garvey KC, Sobota A, O'Brien R, Nigrovic PA, Sharma N, Fishman LN. Transition and transfer of adolescents and young adults with pediatric onset chronic disease: the patient and parent perspective. J Pediatr Rehabil Med. 2014; 7(1):43-51. PMID: 24919937.
    Citations: 18     Fields:    Translation:Humans
  132. Deanehan JK, Nigrovic PA, Milewski MD, Tan Tanny SP, Kimia AA, Smith BG, Nigrovic LE. Synovial fluid findings in children with knee monoarthritis in lyme disease endemic areas. Pediatr Emerg Care. 2014 Jan; 30(1):16-9. PMID: 24365728.
    Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
  133. Henderson LA, Loring SH, Dellaripa PF, Nigrovic P. Dr. Henderson, et al reply. J Rheumatol. 2013 Nov; 40(11):1926. PMID: 24344358.
    Citations:    Fields:    Translation:Humans
  134. Romero V, Fert-Bober J, Nigrovic PA, Darrah E, Haque UJ, Lee DM, van Eyk J, Rosen A, Andrade F. Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis. Sci Transl Med. 2013 Oct 30; 5(209):209ra150. PMID: 24174326.
    Citations: 95     Fields:    Translation:HumansCells
  135. Ringold S, Weiss PF, Beukelman T, DeWitt EM, Ilowite NT, Kimura Y, Laxer RM, Lovell DJ, Nigrovic PA, Robinson AB, Vehe RK. 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications. Arthritis Rheum. 2013 Oct; 65(10):2499-512. PMID: 24092554; PMCID: PMC5408575.
    Citations: 84     Fields:    Translation:HumansPHPublic Health
  136. Nigrovic PA. Sweets are good for you: fine tuning antibodies via glycosylation. Arthritis Rheum. 2013 Oct; 65(10):2541-4. PMID: 23839979.
    Citations: 2     Fields:    Translation:HumansCells
  137. Ringold S, Weiss PF, Beukelman T, Dewitt EM, Ilowite NT, Kimura Y, Laxer RM, Lovell DJ, Nigrovic PA, Robinson AB, Vehe RK. 2013 update of the 2011 American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: recommendations for the medical therapy of children with systemic juvenile idiopathic arthritis and tuberculosis screening among children receiving biologic medications. Arthritis Care Res (Hoboken). 2013 Oct; 65(10):1551-63. PMID: 24078300.
    Citations: 25     Fields:    Translation:HumansPHPublic Health
  138. Hinks A, Cobb J, Marion MC, Prahalad S, Sudman M, Bowes J, Martin P, Comeau ME, Sajuthi S, Andrews R, Brown M, Chen WM, Concannon P, Deloukas P, Edkins S, Eyre S, Gaffney PM, Guthery SL, Guthridge JM, Hunt SE, James JA, Keddache M, Moser KL, Nigrovic PA, Onengut-Gumuscu S, Onslow ML, Rosé CD, Rich SS, Steel KJ, Wakeland EK, Wallace CA, Wedderburn LR, Woo P, Bohnsack JF, Haas JP, Glass DN, Langefeld CD, Thomson W, Thompson SD. Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet. 2013 Jun; 45(6):664-9. PMID: 23603761.
    Citations: 165     Fields:    Translation:Humans
  139. Ringold S, Beukelman T, Nigrovic PA, Kimura Y. Race, ethnicity, and disease outcomes in juvenile idiopathic arthritis: a cross-sectional analysis of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry. J Rheumatol. 2013 Jun; 40(6):936-42. PMID: 23588937.
    Citations: 20     Fields:    Translation:Humans
  140. Ackerman ME, Crispin M, Yu X, Baruah K, Boesch AW, Harvey DJ, Dugast AS, Heizen EL, Ercan A, Choi I, Streeck H, Nigrovic PA, Bailey-Kellogg C, Scanlan C, Alter G. Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity. J Clin Invest. 2013 May; 123(5):2183-92. PMID: 23563315; PMCID: PMC3637034.
    Citations: 169     Fields:    Translation:HumansCells
  141. Lee PY, Wang JX, Parisini E, Dascher CC, Nigrovic PA. Ly6 family proteins in neutrophil biology. J Leukoc Biol. 2013 Oct; 94(4):585-94. PMID: 23543767.
    Citations: 124     Fields:    Translation:HumansAnimalsCells
  142. Larman HB, Laserson U, Querol L, Verhaeghen K, Solimini NL, Xu GJ, Klarenbeek PL, Church GM, Hafler DA, Plenge RM, Nigrovic PA, De Jager PL, Weets I, Martens GA, O'Connor KC, Elledge SJ. PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis. J Autoimmun. 2013 Jun; 43:1-9. PMID: 23497938; PMCID: PMC3677742.
    Citations: 27     Fields:    Translation:HumansCells
  143. Henderson LA, Loring SH, Gill RR, Liao KP, Ishizawar R, Kim S, Perlmutter-Goldenson R, Rothman D, Son MB, Stoll ML, Zemel LS, Sandborg C, Dellaripa PF, Nigrovic PA. Shrinking lung syndrome as a manifestation of pleuritis: a new model based on pulmonary physiological studies. J Rheumatol. 2013 Mar; 40(3):273-81. PMID: 23378468.
    Citations: 10     Fields:    Translation:Humans
  144. Nigrovic PA. Ly6G: a work in progress--author's reply to Yipp. Blood. 2013 Jan 03; 121(1):242-3. PMID: 23409288.
    Citations: 2     Fields:    Translation:AnimalsCells
  145. Cloutier N, Tan S, Boudreau LH, Cramb C, Subbaiah R, Lahey L, Albert A, Shnayder R, Gobezie R, Nigrovic PA, Farndale RW, Robinson WH, Brisson A, Lee DM, Boilard E. The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes. EMBO Mol Med. 2013 Feb; 5(2):235-49. PMID: 23165896; PMCID: PMC3569640.
    Citations: 104     Fields:    Translation:Humans
  146. Adamczyk B, Struwe WB, Ercan A, Nigrovic PA, Rudd PM. Characterization of fibrinogen glycosylation and its importance for serum/plasma N-glycome analysis. J Proteome Res. 2013 Jan 04; 12(1):444-54. PMID: 23151259.
    Citations: 17     Fields:    Translation:HumansCells
  147. Kaieda S, Wang JX, Shnayder R, Fishgal N, Hei H, Lee RT, Stevens RL, Nigrovic PA. Interleukin-33 primes mast cells for activation by IgG immune complexes. PLoS One. 2012; 7(10):e47252. PMID: 23071771.
    Citations: 7     Fields:    Translation:AnimalsCells
  148. Ercan A, Barnes MG, Hazen M, Tory H, Henderson L, Dedeoglu F, Fuhlbrigge RC, Grom A, Holm IA, Kellogg M, Kim S, Adamczyk B, Rudd PM, Son MB, Sundel RP, Foell D, Glass DN, Thompson SD, Nigrovic PA. Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation. Arthritis Rheum. 2012 Sep; 64(9):3025-33. PMID: 22549726; PMCID: PMC3429730.
    Citations: 17     Fields:    Translation:HumansCells
  149. Boilard E, Blanco P, Nigrovic PA. Platelets: active players in the pathogenesis of arthritis and SLE. Nat Rev Rheumatol. 2012 Sep; 8(9):534-42. PMID: 22868927.
    Citations: 76     Fields:    Translation:HumansAnimalsCells
  150. DeWitt EM, Kimura Y, Beukelman T, Nigrovic PA, Onel K, Prahalad S, Schneider R, Stoll ML, Angeles-Han S, Milojevic D, Schikler KN, Vehe RK, Weiss JE, Weiss P, Ilowite NT, Wallace CA. Consensus treatment plans for new-onset systemic juvenile idiopathic arthritis. Arthritis Care Res (Hoboken). 2012 Jul; 64(7):1001-10. PMID: 22290637.
    Citations: 79     Fields:    Translation:Humans
  151. Wang JX, Bair AM, King SL, Shnayder R, Huang YF, Shieh CC, Soberman RJ, Fuhlbrigge RC, Nigrovic PA. Ly6G ligation blocks recruitment of neutrophils via a ß2-integrin-dependent mechanism. Blood. 2012 Aug 16; 120(7):1489-98. PMID: 22661700; PMCID: PMC3423786.
    Citations: 46     Fields:    Translation:AnimalsCells
  152. Cloutier N, Paré A, Farndale RW, Schumacher HR, Nigrovic PA, Lacroix S, Boilard E. Platelets can enhance vascular permeability. Blood. 2012 Aug 09; 120(6):1334-43. PMID: 22544703.
    Citations: 87     Fields:    Translation:HumansAnimalsCells
  153. Adachi R, Krilis SA, Nigrovic PA, Hamilton MJ, Chung K, Thakurdas SM, Boyce JA, Anderson P, Stevens RL. Ras guanine nucleotide-releasing protein-4 (RasGRP4) involvement in experimental arthritis and colitis. J Biol Chem. 2012 Jun 08; 287(24):20047-55. PMID: 22511759.
    Citations: 13     Fields:    Translation:AnimalsCells
  154. Ercan A, Cui J, Hazen MM, Batliwalla F, Royle L, Rudd PM, Coblyn JS, Shadick N, Weinblatt ME, Gregersen P, Lee DM, Nigrovic PA. Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis. Arthritis Res Ther. 2012 Mar 05; 14(2):R43. PMID: 22390545.
    Citations: 15     Fields:    Translation:Humans
  155. Stoll ML, Nigrovic PA, Gotte AC, Punaro M. Clinical comparison of early-onset psoriatic and non-psoriatic oligoarticular juvenile idiopathic arthritis. Clin Exp Rheumatol. 2011 May-Jun; 29(3):582-8. PMID: 21385553.
    Citations: 12     Fields:    Translation:Humans
  156. Nigrovic PA, Mannion M, Prince FH, Zeft A, Rabinovich CE, van Rossum MA, Cortis E, Pardeo M, Miettunen PM, Janow G, Birmingham J, Eggebeen A, Janssen E, Shulman AI, Son MB, Hong S, Jones K, Ilowite NT, Cron RQ, Higgins GC. Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series. Arthritis Rheum. 2011 Feb; 63(2):545-55. PMID: 21280009.
    Citations: 151     Fields:    Translation:HumansCTClinical Trials
  157. Nigrovic PA, Malbec O, Lu B, Markiewski MM, Kepley C, Gerard N, Gerard C, Daëron M, Lee DM. C5a receptor enables participation of mast cells in immune complex arthritis independently of Fc? receptor modulation. Arthritis Rheum. 2010 Nov; 62(11):3322-33. PMID: 20662064; PMCID: PMC2970731.
    Citations: 17     Fields:    Translation:AnimalsCells
  158. Kaieda S, Shin K, Nigrovic PA, Seki K, Lee RT, Stevens RL, Lee DM. Synovial fibroblasts promote the expression and granule accumulation of tryptase via interleukin-33 and its receptor ST-2 (IL1RL1). J Biol Chem. 2010 Jul 09; 285(28):21478-86. PMID: 20427273.
    Citations: 25     Fields:    Translation:AnimalsCells