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Shizuo Mukai, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lu Y, Wang JC, Zeng R, Nagata T, Katz R, Mukai S, Miller JB. Detection of retinal microvascular changes in von Hippel-Lindau disease using optical coherence tomography angiography. PLoS One. 2020; 15(2):e0229213. PMID: 32078656.
    Citations:    
  2. Scott HA, Place EM, Ferenchak K, Zampaglione E, Wagner NE, Chao KR, DiTroia SP, Navarro-Gomez D, Mukai S, Huckfeldt RM, Pierce EA, Bujakowska KM. Expanding the phenotypic spectrum in RDH12-associated retinal disease. Cold Spring Harb Mol Case Stud. 2020 Feb; 6(1). PMID: 32014858.
    Citations:    
  3. Wu W, Zhou G, Han H, Huang X, Jiang H, Mukai S, Kazlauskas A, Cui J, Matsubara JA, Vanhaesebroeck B, Xia X, Wang J, Lei H. PI3Kd as a Novel Therapeutic Target in Pathological Angiogenesis. Diabetes. 2020 Apr; 69(4):736-748. PMID: 31915155.
    Citations:    
  4. Nguyen HV, Nagata T, Mukai S. Inexpensive and Open-Source Devices and Systems for Retinal Imaging. Int Ophthalmol Clin. 2020; 60(1):35-45. PMID: 31855894.
    Citations:    
  5. Hamad AE, Moinuddin O, Blair MP, Schechet SA, Shapiro MJ, Quiram PA, Mammo DA, Berrocal AM, Prakhunhungsit S, Cernichiaro-Espinosa LA, Mukai S, Yonekawa Y, Ung C, Holz ER, Harper CA, Young RC, Besirli CG, Nagiel A, Lee TC, Gupta MP, Walsh MK, Khawly JA, Campbell JP, Kychenthal A, Nudleman ED, Robinson JE, Hartnett ME, Calvo CM, Chang EY. Late-Onset Retinal Findings and Complications in Untreated Retinopathy of Prematurity. Ophthalmol Retina. 2020 06; 4(6):602-612. PMID: 32059986.
    Citations:    
  6. Golas L, Skondra D, Ittiara S, Bajic N, Jeng-Miller KW, Mukai S, Yonekawa Y, Blair MP. Efficacy of Retinal Lesion Screening in Von Hippel-Lindau Patients With Widefield Color Fundus Imaging Versus Widefield FA. Ophthalmic Surg Lasers Imaging Retina. 2019 11 01; 50(11):e260-e265. PMID: 31755976.
    Citations:    
  7. Munson MC, Plewman DL, Baumer KM, Henning R, Zahler CT, Kietzman AT, Beard AA, Mukai S, Diller L, Hamerly G, Shaw BF. Autonomous early detection of eye disease in childhood photographs. Sci Adv. 2019 10; 5(10):eaax6363. PMID: 31616792.
    Citations:    
  8. Gupta MP, Dow E, Jeng-Miller KW, Mukai S, Orlin A, Xu K, Yonekawa Y, Chan RVP. SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY FINDINGS IN COATS DISEASE. Retina. 2019 Jun; 39(6):1177-1185. PMID: 29528979.
    Citations:    Fields:    
  9. Lee Kim E, Weiner AJ, Ung C, Roh M, Wang J, Lee IJ, Huang NT, Stem M, Dahrouj M, Eliott D, Vavvas DG, Young LHY, Williams GA, Garretson BR, Kim IK, Hassan TS, Mukai S, Ruby AJ, Faia LJ, Capone A, Comander J, Kim LA, Wu DM, Drenser KA, Woodward MA, Wolfe JD, Yonekawa Y. Characterization of Epiretinal Proliferation in Full-Thickness Macular Holes and Effects on Surgical Outcomes. Ophthalmol Retina. 2019 08; 3(8):694-702. PMID: 31104985.
    Citations:    
  10. Jeng-Miller KW, Soomro T, Scott NL, Rao P, Marlow E, Chang EY, Ells A, Chau F, Nudleman E, Calvo CM, Patel N, Schwartz R, Cernichiaro-Espinosa LA, Montoya AG, Goldstein J, Harper CA, Baumal CR, Hartnett ME, Harbour JW, Besirli CG, Gupta MP, Chan RVP, Drenser KA, Capone A, Murray TG, Mukai S, Trese MT, Berrocal AM, Wong SC, Yonekawa Y. Longitudinal Examination of Fellow-Eye Vascular Anomalies in Coats' Disease With Widefield Fluorescein Angiography: A Multicenter Study. Ophthalmic Surg Lasers Imaging Retina. 2019 04 01; 50(4):221-227. PMID: 30998243.
    Citations:    
  11. Jakobiec FA, Zakka FR, Papakostas T, Mukai S. Early Neuroblastic and Astrocytic Differentiation Demonstrated Immunohistochemically in a Small Intraocular Medulloepithelioma. Ocul Oncol Pathol. 2018 Apr; 4(3):176-181. PMID: 29765950.
    Citations:    
  12. Zhou G, Duan Y, Ma G, Wu W, Hu Z, Chen N, Chee Y, Cui J, Samad A, Matsubara JA, Mukai S, D'Amore PA, Lei H. Introduction of the MDM2 T309G Mutation in Primary Human Retinal Epithelial Cells Enhances Experimental Proliferative Vitreoretinopathy. Invest Ophthalmol Vis Sci. 2017 10 01; 58(12):5361-5367. PMID: 29049737.
    Citations:    Fields:    Translation:HumansAnimalsCells
  13. Shen BY, Mukai S. A Portable, Inexpensive, Nonmydriatic Fundus Camera Based on the Raspberry Pi® Computer. J Ophthalmol. 2017; 2017:4526243. PMID: 28396802.
    Citations:    
  14. Huang X, Zhou G, Wu W, Ma G, D'Amore PA, Mukai S, Lei H. Editing VEGFR2 Blocks VEGF-Induced Activation of Akt and Tube Formation. Invest Ophthalmol Vis Sci. 2017 02 01; 58(2):1228-1236. PMID: 28241310.
    Citations: 5     Fields:    Translation:HumansCells
  15. Gupta MP, Talcott KE, Kim DY, Agarwal S, Mukai S. Retinal findings and a novel TINF2 mutation in Revesz syndrome: Clinical and molecular correlations with pediatric retinal vasculopathies. Ophthalmic Genet. 2017 Jan-Feb; 38(1):51-60. PMID: 28095086.
    Citations:    Fields:    Translation:Humans
  16. Mouw KW, Yeap BY, Caruso P, Fay A, Misra M, Sethi RV, MacDonald SM, Chen YL, Tarbell NJ, Yock TI, Freitag SK, Munzenrider JE, Grabowski E, Katz M, Kuhlthau K, DeCastro D, Heidary G, Ciralsky J, Mukai S, Shih HA. Analysis of patient outcomes following proton radiation therapy for retinoblastoma. Adv Radiat Oncol. 2017 Jan-Mar; 2(1):44-52. PMID: 28607957.
    Citations:    
  17. Daniels AB, Mukai S. Modern Surgical Techniques in the Management of Retinoblastoma. Int Ophthalmol Clin. 2017; 57(1):195-218. PMID: 27898624.
    Citations:    Fields:    Translation:Humans
  18. Ma G, Duan Y, Huang X, Qian CX, Chee Y, Mukai S, Cui J, Samad A, Matsubara JA, Kazlauskas A, D'Amore PA, Gu S, Lei H. Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases. Invest Ophthalmol Vis Sci. 2016 07 01; 57(8):3935-43. PMID: 27472081.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  19. Yonekawa Y, Wu WC, Kusaka S, Robinson J, Tsujioka D, Kang KB, Shapiro MJ, Padhi TR, Jain L, Sears JE, Kuriyan AE, Berrocal AM, Quiram PA, Gerber AE, Paul Chan RV, Jonas KE, Wong SC, Patel CK, Abbey AM, Spencer R, Blair MP, Chang EY, Papakostas TD, Vavvas DG, Sisk RA, Ferrone PJ, Henderson RH, Olsen KR, Hartnett ME, Chau FY, Mukai S, Murray TG, Thomas BJ, Meza PA, Drenser KA, Trese MT, Capone A. Immediate Sequential Bilateral Pediatric Vitreoretinal Surgery: An International Multicenter Study. Ophthalmology. 2016 08; 123(8):1802-1808. PMID: 27221737.
    Citations:    Fields:    Translation:Humans
  20. Miller JB, Yonekawa Y, Eliott D, Kim IK, Kim LA, Loewenstein JI, Sobrin L, Young LH, Mukai S, Vavvas DG. Long-term Follow-up and Outcomes in Traumatic Macular Holes. Am J Ophthalmol. 2016 06; 166:206-207. PMID: 27084591.
    Citations:    Fields:    Translation:Humans
  21. Miller JB, Yonekawa Y, Eliott D, Kim IK, Kim LA, Loewenstein JI, Sobrin L, Young LH, Mukai S, Vavvas DG. Long-term Follow-up and Outcomes in Traumatic Macular Holes. Am J Ophthalmol. 2015 Dec; 160(6):1255-1258.e1. PMID: 26393438.
    Citations: 3     Fields:    Translation:Humans
  22. Lei H, Qian CX, Lei J, Haddock LJ, Mukai S, Kazlauskas A. RasGAP Promotes Autophagy and Thereby Suppresses Platelet-Derived Growth Factor Receptor-Mediated Signaling Events, Cellular Responses, and Pathology. Mol Cell Biol. 2015 May; 35(10):1673-85. PMID: 25733681.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  23. Leskov I, Mukai S. Laser Therapy Versus Anti-VEGF Agents for Treatment of Retinopathy of Prematurity. Int Ophthalmol Clin. 2015; 55(4):81-90. PMID: 26322428.
    Citations:    Fields:    Translation:Humans
  24. Yonekawa Y, Takusagawa HL, Mukai S. Concurrent threshold retinopathy of prematurity and abusive head trauma. JAMA Ophthalmol. 2015 Jan; 133(1):84. PMID: 25411913.
    Citations:    Fields:    Translation:Humans
  25. Pennock S, Haddock LJ, Mukai S, Kazlauskas A. Vascular endothelial growth factor acts primarily via platelet-derived growth factor receptor a to promote proliferative vitreoretinopathy. Am J Pathol. 2014 Nov; 184(11):3052-68. PMID: 25261788.
    Citations: 7     Fields:    Translation:AnimalsCells
  26. Mouw KW, Sethi RV, Yeap BY, MacDonald SM, Chen YL, Tarbell NJ, Yock TI, Munzenrider JE, Adams J, Grabowski E, Mukai S, Shih HA. Proton radiation therapy for the treatment of retinoblastoma. Int J Radiat Oncol Biol Phys. 2014 Nov 15; 90(4):863-9. PMID: 25227498.
    Citations: 4     Fields:    Translation:Humans
  27. Jakobiec FA, Trief D, Rashid A, Rose MF, Minckler D, Vanderveen D, Mukai S. New insights into the development of infantile intraocular medulloepithelioma. Am J Ophthalmol. 2014 Dec; 158(6):1275-1296.e1. PMID: 25174896.
    Citations: 2     Fields:    Translation:Humans
  28. Jakobiec FA, Rai R, Rashid A, Kanoff J, Mukai S. Dystrophic hyaloid artery remnants and other abnormalities in a buphthalmic eye with retinoblastoma. Surv Ophthalmol. 2014 Nov-Dec; 59(6):636-42. PMID: 25233827.
    Citations: 1     Fields:    Translation:Humans
  29. Pennock S, Haddock LJ, Eliott D, Mukai S, Kazlauskas A. Is neutralizing vitreal growth factors a viable strategy to prevent proliferative vitreoretinopathy? Prog Retin Eye Res. 2014 May; 40:16-34. PMID: 24412519.
    Citations: 25     Fields:    Translation:Humans
  30. Abdolvahabi A, Taylor BW, Holden RL, Shaw EV, Kentsis A, Rodriguez-Galindo C, Mukai S, Shaw BF. Colorimetric and longitudinal analysis of leukocoria in recreational photographs of children with retinoblastoma. PLoS One. 2013; 8(10):e76677. PMID: 24204654.
    Citations: 2     Fields:    Translation:Humans
  31. Sethi RV, Shih HA, Yeap BY, Mouw KW, Petersen R, Kim DY, Munzenrider JE, Grabowski E, Rodriguez-Galindo C, Yock TI, Tarbell NJ, Marcus KJ, Mukai S, MacDonald SM. Second nonocular tumors among survivors of retinoblastoma treated with contemporary photon and proton radiotherapy. Cancer. 2014 Jan 01; 120(1):126-33. PMID: 24122173.
    Citations: 22     Fields:    Translation:Humans
  32. Haddock LJ, Kim DY, Mukai S. Simple, inexpensive technique for high-quality smartphone fundus photography in human and animal eyes. J Ophthalmol. 2013; 2013:518479. PMID: 24171108.
    Citations: 25     
  33. Kim DY, Mukai S. X-linked juvenile retinoschisis (XLRS): a review of genotype-phenotype relationships. Semin Ophthalmol. 2013 Sep-Nov; 28(5-6):392-6. PMID: 24138048.
    Citations: 3     Fields:    Translation:Humans
  34. Sethi RV, MacDonald SM, Kim DY, Mukai S. Radiation therapy: retinal tumors. Dev Ophthalmol. 2013; 52:58-74. PMID: 23989127.
    Citations:    Fields:    Translation:Humans
  35. Yonekawa Y, MacDonald SM, Shildkrot Y, Mukai S. Standard fractionation low-dose proton radiotherapy for diffuse choroidal hemangiomas in pediatric Sturge-Weber syndrome. J AAPOS. 2013 Jun; 17(3):318-22. PMID: 23618630.
    Citations:    Fields:    Translation:Humans
  36. Pennock S, Kim D, Mukai S, Kuhnle M, Chun DW, Matsubara J, Cui J, Ma P, Maberley D, Samad A, Van Geest RJ, Oberstein SL, Schlingemann RO, Kazlauskas A. Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a nonangiogenic blinding disease. Am J Pathol. 2013 May; 182(5):1659-70. PMID: 23582767.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  37. Kim DY, Delori F, Mukai S. Smartphone photography safety. Ophthalmology. 2012 Oct; 119(10):2200-1; author reply 2201. PMID: 23034305.
    Citations: 7     Fields:    Translation:Humans
  38. Lei H, Rheaume MA, Cui J, Mukai S, Maberley D, Samad A, Matsubara J, Kazlauskas A. A novel function of p53: a gatekeeper of retinal detachment. Am J Pathol. 2012 Sep; 181(3):866-74. PMID: 22901751.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  39. Conkrite K, Sundby M, Mu D, Mukai S, MacPherson D. Cooperation between Rb and Arf in suppressing mouse retinoblastoma. J Clin Invest. 2012 May; 122(5):1726-33. PMID: 22484813.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  40. Pennock S, Rheaume MA, Mukai S, Kazlauskas A. A novel strategy to develop therapeutic approaches to prevent proliferative vitreoretinopathy. Am J Pathol. 2011 Dec; 179(6):2931-40. PMID: 22035642.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  41. Lei H, Rhéaume MA, Velez G, Mukai S, Kazlauskas A. Expression of PDGFRa is a determinant of the PVR potential of ARPE19 cells. Invest Ophthalmol Vis Sci. 2011 Aug 24; 52(9):5016-21. PMID: 21642621.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  42. Conkrite K, Sundby M, Mukai S, Thomson JM, Mu D, Hammond SM, MacPherson D. miR-17~92 cooperates with RB pathway mutations to promote retinoblastoma. Genes Dev. 2011 Aug 15; 25(16):1734-45. PMID: 21816922.
    Citations: 75     Fields:    Translation:HumansAnimalsCells
  43. Vavvas D, Kim I, Lane AM, Chaglassian A, Mukai S, Gragoudas E. Posterior uveal melanoma in young patients treated with proton beam therapy. Retina. 2010 Sep; 30(8):1267-71. PMID: 20224468.
    Citations: 2     Fields:    Translation:Humans
  44. Daniels AB, Jakobiec FA, Westerfeld CB, Hagiwara A, Michaud N, Mukai S. Idiopathic subfoveal choroidal neovascular membrane in a 21-month-old child: ultrastructural features and implication for membranogenesis. J AAPOS. 2010 Jun; 14(3):244-50. PMID: 20417139.
    Citations: 1     Fields:    Translation:HumansCells
  45. Salehi-Had H, Andreoli CM, Andreoli MT, Kloek CE, Mukai S. Visual outcomes of vitreoretinal surgery in eyes with severe open-globe injury presenting with no-light-perception vision. Graefes Arch Clin Exp Ophthalmol. 2009 Apr; 247(4):477-83. PMID: 19172288.
    Citations: 14     Fields:    Translation:Humans
  46. Esmaili DD, Mukai S, Jakobiec FA, Kim IK, Gragoudas ES. Ocular melanocytoma. Int Ophthalmol Clin. 2009; 49(1):165-75. PMID: 19125075.
    Citations:    Fields:    Translation:Humans
  47. Westerfeld C, Mukai S. Retinal and choroidal biopsy. Int Ophthalmol Clin. 2009; 49(1):145-54. PMID: 19125073.
    Citations: 1     Fields:    Translation:Humans
  48. Poulaki V, Mukai S. Retinoblastoma: genetics and pathology. Int Ophthalmol Clin. 2009; 49(1):155-64. PMID: 19125074.
    Citations: 3     Fields:    Translation:Humans
  49. Kiss S, Leiderman YI, Mukai S. Diagnosis, classification, and treatment of retinoblastoma. Int Ophthalmol Clin. 2008; 48(2):135-47. PMID: 18427266.
    Citations: 6     Fields:    Translation:Humans
  50. Rubin MP, Mukai S. Coats' disease. Int Ophthalmol Clin. 2008; 48(2):149-58. PMID: 18427267.
    Citations: 3     Fields:    Translation:Humans
  51. Andreoli CM, Warden SM, Mukai S. Inherited proliferative vitreoretinopathies of childhood. Int Ophthalmol Clin. 2008; 48(2):159-74. PMID: 18427268.
    Citations:    Fields:    Translation:Humans
  52. Westerfeld C, Mukai S. Stargardt's disease and the ABCR gene. Semin Ophthalmol. 2008 Jan-Feb; 23(1):59-65. PMID: 18214793.
    Citations: 11     Fields:    Translation:HumansCells
  53. Warden SM, Andreoli CM, Mukai S. The Wnt signaling pathway in familial exudative vitreoretinopathy and Norrie disease. Semin Ophthalmol. 2007 Oct-Dec; 22(4):211-7. PMID: 18097984.
    Citations: 13     Fields:    Translation:HumansCells
  54. Leiderman YI, Kiss S, Mukai S. Molecular genetics of RB1--the retinoblastoma gene. Semin Ophthalmol. 2007 Oct-Dec; 22(4):247-54. PMID: 18097988.
    Citations: 12     Fields:    Translation:Humans
  55. MacPherson D, Conkrite K, Tam M, Mukai S, Mu D, Jacks T. Murine bilateral retinoblastoma exhibiting rapid-onset, metastatic progression and N-myc gene amplification. EMBO J. 2007 Feb 07; 26(3):784-94. PMID: 17235288.
    Citations: 28     Fields:    Translation:Animals
  56. Christoforidis JB, Warden SM, Farrell GM, Baker M, Mukai S. Histology of retina overlying bacterial subretinal abscess and implications for treatment. Retin Cases Brief Rep. 2007; 1(4):257-60. PMID: 25390996.
    Citations:    Fields:    
  57. Warden SM, Mukai S. Pars plana vitrectomy in eyes treated for retinoblastoma. Retina. 2006 Sep; 26(7 Suppl):S53-6. PMID: 16946680.
    Citations: 2     Fields:    Translation:Humans
  58. Ament CS, Zacks DN, Lane AM, Krzystolik M, D'Amico DJ, Mukai S, Young LH, Loewenstein J, Arroyo J, Miller JW. Predictors of visual outcome and choroidal neovascular membrane formation after traumatic choroidal rupture. Arch Ophthalmol. 2006 Jul; 124(7):957-66. PMID: 16832018.
    Citations: 11     Fields:    Translation:Humans
  59. Walton DS, Mukai S, Grabowski EF, Munzenrider JE, Dryja TP. Case records of the Massachusetts General Hospital. Case 5-2006. An 11-year-old girl with loss of vision in the right eye. N Engl J Med. 2006 Feb 16; 354(7):741-8. PMID: 16481642.
    Citations: 3     Fields:    Translation:Humans
  60. Melson MR, Mukai S. Intraocular lymphoma. Int Ophthalmol Clin. 2006; 46(2):69-77. PMID: 16770155.
    Citations:    Fields:    Translation:Humans
  61. Gregory MS, Koh S, Huang E, Saff RR, Marshak-Rothstein A, Mukai S, Ksander BR. A novel treatment for ocular tumors using membrane FasL vesicles to activate innate immunity and terminate immune privilege. Invest Ophthalmol Vis Sci. 2005 Jul; 46(7):2495-502. PMID: 15980241.
    Citations: 2     Fields:    Translation:AnimalsCells
  62. Barouch FC, Benson MD, Mukai S. Isolated vitreoretinal amyloidosis in the absence of transthyretin mutations. Arch Ophthalmol. 2004 Jan; 122(1):123-5. PMID: 14718311.
    Citations: 1     Fields:    Translation:Humans
  63. Kusano Y, Endo S, Mukai S, Yamaguchi T. Retinopathy after percutaneous transluminal coronary angioplasty and stent insertion for acute myocardial infarction. Am J Ophthalmol. 2003 Sep; 136(3):557-60. PMID: 12967820.
    Citations:    Fields:    Translation:Humans
  64. Chau KY, Manfioletti G, Cheung-Chau KW, Fusco A, Dhomen N, Sowden JC, Sasabe T, Mukai S, Ono SJ. Derepression of HMGA2 gene expression in retinoblastoma is associated with cell proliferation. Mol Med. 2003 May-Aug; 9(5-8):154-65. PMID: 14571323.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  65. Fitzek MM, Dahlberg WK, Nagasawa H, Mukai S, Munzenrider JE, Little JB. Unexpected sensitivity to radiation of fibroblasts from unaffected parents of children with hereditary retinoblastoma. Int J Cancer. 2002 Jun 10; 99(5):764-8. PMID: 12115515.
    Citations: 1     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.