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Antoine Karnoub, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tu Z, Schmöllerl J, Cuiffo BG, Karnoub AE. Microenvironmental Regulation of Long Noncoding RNA LINC01133 Promotes Cancer Stem Cell-Like Phenotypic Traits in Triple-Negative Breast Cancers. Stem Cells. 2019 10; 37(10):1281-1292. PMID: 31283068.
    Citations:    
  2. Thomas C, Henry W, Cuiffo BG, Collmann AY, Marangoni E, Benhamo V, Bhasin MK, Fan C, Fuhrmann L, Baldwin AS, Perou C, Vincent-Salomon A, Toker A, Karnoub AE. Pentraxin-3 is a PI3K signaling target that promotes stem cell-like traits in basal-like breast cancers. Sci Signal. 2017 02 21; 10(467). PMID: 28223411.
    Citations:    Fields:    Translation:HumansCells
  3. Karnoub AE, VanHook AM. Science Signaling Podcast for 21 February 2017: Pentraxin-3 in basal-like breast cancer. Sci Signal. 2017 02 21; 10(467). PMID: 28223415.
    Citations:    Fields:    
  4. Reynaud C, Ferreras L, Di Mauro P, Kan C, Croset M, Bonnelye E, Pez F, Thomas C, Aimond G, Karnoub AE, Brevet M, Clézardin P. Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in Bone. Cancer Res. 2017 01 15; 77(2):268-278. PMID: 27742687.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  5. Cuiffo BG, Karnoub AE. Silencing FOXP2 in breast cancer cells promotes cancer stem cell traits and metastasis. Mol Cell Oncol. 2016 May; 3(3):e1019022. PMID: 27314063.
    Citations: 4     
  6. Tasoglu S, Khoory JA, Tekin HC, Thomas C, Karnoub AE, Ghiran IC, Demirci U. Cytometry: Levitational Image Cytometry with Temporal Resolution (Adv. Mater. 26/2015). Adv Mater. 2015 Jul; 27(26):3900. PMID: 26149363.
    Citations:    
  7. Tasoglu S, Khoory JA, Tekin HC, Thomas C, Karnoub AE, Ghiran IC, Demirci U. Levitational Image Cytometry with Temporal Resolution. Adv Mater. 2015 Jul 08; 27(26):3901-8. PMID: 26058598.
    Citations: 9     Fields:    Translation:HumansCells
  8. Cuiffo BG, Campagne A, Bell GW, Lembo A, Orso F, Lien EC, Bhasin MK, Raimo M, Hanson SE, Marusyk A, El-Ashry D, Hematti P, Polyak K, Mechta-Grigoriou F, Mariani O, Volinia S, Vincent-Salomon A, Taverna D, Karnoub AE. MSC-regulated microRNAs converge on the transcription factor FOXP2 and promote breast cancer metastasis. Cell Stem Cell. 2014 Dec 04; 15(6):762-74. PMID: 25515522.
    Citations: 34     Fields:    Translation:HumansCells
  9. Thomas C, Karnoub AE. Lysyl oxidase at the crossroads of mesenchymal stem cells and epithelial-mesenchymal transition. Oncotarget. 2013 Mar; 4(3):376-7. PMID: 23530115.
    Citations: 4     Fields:    Translation:HumansCells
  10. El-Haibi CP, Bell GW, Zhang J, Collmann AY, Wood D, Scherber CM, Csizmadia E, Mariani O, Zhu C, Campagne A, Toner M, Bhatia SN, Irimia D, Vincent-Salomon A, Karnoub AE. Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17460-5. PMID: 23033492.
    Citations: 50     Fields:    Translation:HumansCells
  11. Cuiffo BG, Karnoub AE. Mesenchymal stem cells in tumor development: emerging roles and concepts. Cell Adh Migr. 2012 May-Jun; 6(3):220-30. PMID: 22863739.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  12. El-Haibi CP, Karnoub AE. Mesenchymal stem cells in the pathogenesis and therapy of breast cancer. J Mammary Gland Biol Neoplasia. 2010 Dec; 15(4):399-409. PMID: 21170761.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  13. Karnoub AE, Weinberg RA. Ras oncogenes: split personalities. Nat Rev Mol Cell Biol. 2008 Jul; 9(7):517-31. PMID: 18568040.
    Citations: 428     Fields:    Translation:HumansAnimalsCells
  14. Scheel C, Onder T, Karnoub A, Weinberg RA. Adaptation versus selection: the origins of metastatic behavior. Cancer Res. 2007 Dec 15; 67(24):11476-9; discussion 11479-80. PMID: 18089773.
    Citations: 42     Fields:    Translation:HumansCells
  15. Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, Richardson AL, Polyak K, Tubo R, Weinberg RA. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature. 2007 Oct 04; 449(7162):557-63. PMID: 17914389.
    Citations: 926     Fields:    Translation:HumansAnimalsCells
  16. Ince TA, Richardson AL, Bell GW, Saitoh M, Godar S, Karnoub AE, Iglehart JD, Weinberg RA. Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes. Cancer Cell. 2007 Aug; 12(2):160-70. PMID: 17692807.
    Citations: 141     Fields:    Translation:HumansAnimalsCells
  17. Yohe ME, Rossman KL, Gardner OS, Karnoub AE, Snyder JT, Gershburg S, Graves LM, Der CJ, Sondek J. Auto-inhibition of the Dbl family protein Tim by an N-terminal helical motif. J Biol Chem. 2007 May 04; 282(18):13813-23. PMID: 17337446.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  18. Karnoub AE, Weinberg RA. Chemokine networks and breast cancer metastasis. Breast Dis. 2006-2007; 26:75-85. PMID: 17473367.
    Citations: 36     Fields:    Translation:HumansCells
  19. Singh A, Karnoub AE, Palmby TR, Lengyel E, Sondek J, Der CJ. Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation. Oncogene. 2004 Dec 16; 23(58):9369-80. PMID: 15516977.
    Citations: 66     Fields:    Translation:AnimalsCells
  20. Palmby TR, Abe K, Karnoub AE, Der CJ. Vav transformation requires activation of multiple GTPases and regulation of gene expression. Mol Cancer Res. 2004 Dec; 2(12):702-11. PMID: 15634759.
    Citations: 9     Fields:    Translation:AnimalsCells
  21. Karnoub AE, Symons M, Campbell SL, Der CJ. Molecular basis for Rho GTPase signaling specificity. Breast Cancer Res Treat. 2004 Mar; 84(1):61-71. PMID: 14999155.
    Citations: 27     Fields:    Translation:HumansCells
  22. Pruitt WM, Karnoub AE, Rakauskas AC, Guipponi M, Antonarakis SE, Kurakin A, Kay BK, Sondek J, Siderovski DP, Der CJ. Role of the pleckstrin homology domain in intersectin-L Dbl homology domain activation of Cdc42 and signaling. Biochim Biophys Acta. 2003 Apr 07; 1640(1):61-8. PMID: 12676355.
    Citations: 8     Fields:    Translation:AnimalsCells
  23. Fuentes EJ, Karnoub AE, Booden MA, Der CJ, Campbell SL. Critical role of the pleckstrin homology domain in Dbs signaling and growth regulation. J Biol Chem. 2003 Jun 06; 278(23):21188-96. PMID: 12637530.
    Citations: 8     Fields:    Translation:AnimalsCells
  24. Wennerberg K, Ellerbroek SM, Liu RY, Karnoub AE, Burridge K, Der CJ. RhoG signals in parallel with Rac1 and Cdc42. J Biol Chem. 2002 Dec 06; 277(49):47810-7. PMID: 12376551.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  25. Hamad NM, Elconin JH, Karnoub AE, Bai W, Rich JN, Abraham RT, Der CJ, Counter CM. Distinct requirements for Ras oncogenesis in human versus mouse cells. Genes Dev. 2002 Aug 15; 16(16):2045-57. PMID: 12183360.
    Citations: 141     Fields:    Translation:HumansAnimalsCells
  26. Thapar R, Karnoub AE, Campbell SL. Structural and biophysical insights into the role of the insert region in Rac1 function. Biochemistry. 2002 Mar 26; 41(12):3875-83. PMID: 11900529.
    Citations: 4     Fields:    Translation:Cells
  27. Karnoub AE, Worthylake DK, Rossman KL, Pruitt WM, Campbell SL, Sondek J, Der CJ. Molecular basis for Rac1 recognition by guanine nucleotide exchange factors. Nat Struct Biol. 2001 Dec; 8(12):1037-41. PMID: 11685227.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  28. Lambert JM, Karnoub AE, Graves LM, Campbell SL, Der CJ. Role of MLK3-mediated activation of p70 S6 kinase in Rac1 transformation. J Biol Chem. 2002 Feb 15; 277(7):4770-7. PMID: 11713255.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  29. Karnoub AE, Der CJ, Campbell SL. The insert region of Rac1 is essential for membrane ruffling but not cellular transformation. Mol Cell Biol. 2001 Apr; 21(8):2847-57. PMID: 11283263.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.