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John G Flanagan, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01NS069913 (FLANAGAN, JOHN G) Jul 1, 2011 - Mar 31, 2021
    NIH/NINDS
    Molecular mechanisms of neuron motility and axon guidance
    Role: Principal Investigator
  2. R13NS045340 (FLANAGAN, JOHN G) Jan 1, 2003 - Dec 31, 2003
    NIH/NINDS
    Axonal Connections: Cues for Development &Regeneration
    Role: Principal Investigator
  3. P01NS040043 (VAN VACTOR, DAVID L) Aug 15, 2000 - Apr 30, 2011
    NIH/NINDS
    Signal Transduction in Neuron Migration &Axon Guidance
    Role: Co-Principal Investigator
  4. R01EY011559 (FLANAGAN, JOHN G) Sep 30, 1996 - Mar 31, 2017
    NIH/NEI
    Cell-Cell Signaling in Development and Regeneration of Visual Connections
    Role: Principal Investigator
  5. R01DK045580 (FLANAGAN, JOHN G) Sep 30, 1992 - Sep 29, 1996
    NIH/NIDDK
    IDENTIFICATION AND ANALYSIS OF ORPHAN RECEPTOR LIGANDS
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Gao Q, Yang JY, Moremen KW, Flanagan JG, Prestegard JH. Structural Characterization of a Heparan Sulfate Pentamer Interacting with LAR-Ig1-2. Biochemistry. 2018 04 17; 57(15):2189-2199. PMID: 29570275.
    View in: PubMed
  2. Mwanza JC, Lee G, Budenz DL, Warren JL, Wall M, Artes PH, Callan TM, Flanagan JG. Validation of the UNC OCT Index for the Diagnosis of Early Glaucoma. Transl Vis Sci Technol. 2018 Apr; 7(2):16. PMID: 29629238.
    View in: PubMed
  3. Liu HH, Zhang L, Shi M, Chen L, Flanagan JG. Comparison of laser and circumlimbal suture induced elevation of intraocular pressure in albino CD-1 mice. PLoS One. 2017; 12(11):e0189094. PMID: 29190824.
    View in: PubMed
  4. Livne-Bar I, Wei J, Liu HH, Alqawlaq S, Won GJ, Tuccitto A, Gronert K, Flanagan JG, Sivak JM. Astrocyte-derived lipoxins A4 and B4 promote neuroprotection from acute and chronic injury. J Clin Invest. 2017 Dec 01; 127(12):4403-4414. PMID: 29106385.
    View in: PubMed
  5. Voorhees AP, Jan NJ, Austin ME, Flanagan JG, Sivak JM, Bilonick RA, Sigal IA. Lamina Cribrosa Pore Shape and Size as Predictors of Neural Tissue Mechanical Insult. Invest Ophthalmol Vis Sci. 2017 10 01; 58(12):5336-5346. PMID: 29049736.
    View in: PubMed
  6. Zhang L, Li G, Shi M, Liu HH, Ge S, Ou Y, Flanagan JG, Chen L. Establishment and Characterization of an Acute Model of Ocular Hypertension by Laser-Induced Occlusion of Episcleral Veins. Invest Ophthalmol Vis Sci. 2017 08 01; 58(10):3879-3886. PMID: 28763561.
    View in: PubMed
  7. van Katwyk S, Jin YP, Trope GE, Buys Y, Masucci L, Wedge R, Flanagan J, Brent MH, El-Defrawy S, Tu HA, Thavorn K. Cost-Utility Analysis of Extending Public Health Insurance Coverage to Include Diabetic Retinopathy Screening by Optometrists. Value Health. 2017 09; 20(8):1034-1040. PMID: 28964434.
    View in: PubMed
  8. Khuu LA, Tayyari F, Sivak JM, Flanagan JG, Singer S, Brent MH, Huang D, Tan O, Hudson C. Aqueous humor endothelin-1 and total retinal blood flow in patients with non-proliferative diabetic retinopathy. Eye (Lond). 2017 Oct; 31(10):1443-1450. PMID: 28548649.
    View in: PubMed
  9. Beltran-Agulló L, Buys YM, Jahan F, Shapiro CM, Flanagan JG, Cheng J, Trope GE. Twenty-four hour intraocular pressure monitoring with the SENSIMED Triggerfish contact lens: effect of body posture during sleep. Br J Ophthalmol. 2017 10; 101(10):1323-1328. PMID: 28270491.
    View in: PubMed
  10. Liu HH, Flanagan JG. A Mouse Model of Chronic Ocular Hypertension Induced by Circumlimbal Suture. Invest Ophthalmol Vis Sci. 2017 01 01; 58(1):353-361. PMID: 28118662.
    View in: PubMed
  11. Livne-Bar I, Lam S, Chan D, Guo X, Askar I, Nahirnyj A, Flanagan JG, Sivak JM. Pharmacologic inhibition of reactive gliosis blocks TNF-a-mediated neuronal apoptosis. Cell Death Dis. 2016 09 29; 7(9):e2386. PMID: 27685630.
    View in: PubMed
  12. Khuu LA, Tayyari F, Sivak JM, Flanagan JG, Singer S, Brent MH, Huang D, Tan O, Hudson C. Aqueous humour concentrations of TGF-ß, PLGF and FGF-1 and total retinal blood flow in patients with early non-proliferative diabetic retinopathy. Acta Ophthalmol. 2017 May; 95(3):e206-e211. PMID: 27678201.
    View in: PubMed
  13. Shahidi AM, Hudson C, Tayyari F, Flanagan JG. Retinal Oxygen Saturation in Patients with Primary Open-angle Glaucoma Using a Non-flash Hypespectral Camera. Curr Eye Res. 2017 04; 42(4):557-561. PMID: 27612016.
    View in: PubMed
  14. Preitner N, Quan J, Li X, Nielsen FC, Flanagan JG. IMP2 axonal localization, RNA interactome, and function in the development of axon trajectories. Development. 2016 08 01; 143(15):2753-9. PMID: 27385015; PMCID: PMC5004904 [Available on 08/01/17].
  15. Cheng RW, Yusof F, Tsui E, Jong M, Duffin J, Flanagan JG, Fisher JA, Hudson C. Relationship between retinal blood flow and arterial oxygen. J Physiol. 2016 Feb 01; 594(3):625-40. PMID: 26607393.
    View in: PubMed
  16. Exler RE, Guo X, Chan D, Livne-Bar I, Vicic N, Flanagan JG, Sivak JM. Biomechanical insult switches PEA-15 activity to uncouple its anti-apoptotic function and promote erk mediated tissue remodeling. Exp Cell Res. 2016 Jan 15; 340(2):283-94. PMID: 26615958.
    View in: PubMed
  17. Tayyari F, Khuu LA, Flanagan JG, Singer S, Brent MH, Hudson C. Retinal Blood Flow and Retinal Blood Oxygen Saturation in Mild to Moderate Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2015 Oct; 56(11):6796-800. PMID: 26567792.
    View in: PubMed
  18. Realini T, Zangwill LM, Flanagan JG, Garway-Heath D, Patella VM, Johnson CA, Artes PH, Gaddie IB, Fingeret M. Normative Databases for Imaging Instrumentation. J Glaucoma. 2015 Aug; 24(6):480-3. PMID: 25265003; PMCID: PMC4699581.
  19. Connaughton DM, Bukhari S, Conlon P, Cassidy E, O'Toole M, Mohamad M, Flanagan J, Butler T, O'Leary A, Wong L, O'Regan J, Moran S, O'Kelly P, Logan V, Griffin B, Griffin M, Lavin P, Little MA, Conlon P. The Irish Kidney Gene Project--Prevalence of Family History in Patients with Kidney Disease in Ireland. Nephron. 2015; 130(4):293-301. PMID: 26202451.
    View in: PubMed
  20. Tayyari F, Yusof F, Vymyslicky M, Tan O, Huang D, Flanagan JG, Hudson C. Variability and repeatability of quantitative, Fourier-domain optical coherence tomography Doppler blood flow in young and elderly healthy subjects. Invest Ophthalmol Vis Sci. 2014 Oct 21; 55(12):7716-25. PMID: 25335983.
    View in: PubMed
  21. Shahidi AM, Hudson C, Patel SR, Flanagan JG. The effect of hypercapnia on the sensitivity to flicker defined stimuli. Br J Ophthalmol. 2015 Mar; 99(3):323-8. PMID: 25232025.
    View in: PubMed
  22. Sanfilippo PG, Grimm JL, Flanagan JG, Lathrop KL, Sigal IA. Application of Elliptic Fourier analysis to describe the lamina cribrosa shape with age and intraocular pressure. Exp Eye Res. 2014 Nov; 128:1-7. PMID: 25193035; PMCID: PMC4252246.
  23. Preitner N, Quan J, Nowakowski DW, Hancock ML, Shi J, Tcherkezian J, Young-Pearse TL, Flanagan JG. APC is an RNA-binding protein, and its interactome provides a link to neural development and microtubule assembly. Cell. 2014 Jul 17; 158(2):368-382. PMID: 25036633; PMCID: PMC4133101.
  24. Rose K, Jong M, Yusof F, Tayyari F, Tan O, Huang D, Sadda SR, Flanagan JG, Hudson C. Grader learning effect and reproducibility of Doppler Spectral-Domain Optical Coherence Tomography derived retinal blood flow measurements. Acta Ophthalmol. 2014 Dec; 92(8):e630-6. PMID: 25041925.
    View in: PubMed
  25. Shahidi AM, Patel SR, Huang D, Tan O, Flanagan JG, Hudson C. Assessment of total retinal blood flow using Doppler Fourier Domain Optical Coherence Tomography during systemic hypercapnia and hypocapnia. Physiol Rep. 2014 Jul 01; 2(7). PMID: 25038117; PMCID: PMC4187559.
  26. Alqawlaq S, Sivak JM, Huzil JT, Ivanova MV, Flanagan JG, Beazely MA, Foldvari M. Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: towards non-invasive glaucoma gene therapy. Nanomedicine. 2014 Nov; 10(8):1637-47. PMID: 24905400.
    View in: PubMed
  27. Rose K, Flanagan JG, Patel SR, Cheng R, Hudson C. Retinal blood flow and vascular reactivity in chronic smokers. Invest Ophthalmol Vis Sci. 2014 May 06; 55(7):4266-76. PMID: 24801513.
    View in: PubMed
  28. Guo X, Dason ES, Zanon-Moreno V, Jiang Q, Nahirnyj A, Chan D, Flanagan JG, Sivak JM. PGC-1a signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina. Am J Pathol. 2014 Apr; 184(4):1017-1029. PMID: 24508229.
    View in: PubMed
  29. Lee DH, Mirza R, Flanagan JG, Anderson AK. Optical origins of opposing facial expression actions. Psychol Sci. 2014 Mar; 25(3):745-52. PMID: 24463554.
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  30. Kourkoutas D, Buys YM, Flanagan JG, Karamaounas N, Georgopoulos G, Iliakis E, Moschos MM, Trope GE. Clinical significance of optic disc progression by topographic change analysis maps in glaucoma: an 8-year follow-up study. J Ophthalmol. 2014; 2014:987389. PMID: 24672711; PMCID: PMC3942191.
  31. Hancock ML, Preitner N, Quan J, Flanagan JG. MicroRNA-132 is enriched in developing axons, locally regulates Rasa1 mRNA, and promotes axon extension. J Neurosci. 2014 Jan 01; 34(1):66-78. PMID: 24381269; PMCID: PMC3866495.
  32. Patel SR, Hudson C, Flanagan JG, Heitmar R. The effect of simulated cataract light scatter on retinal vessel oximetry. Exp Eye Res. 2013 Nov; 116:185-9. PMID: 24056207.
    View in: PubMed
  33. Patel SR, Flanagan JG, Shahidi AM, Sylvestre JP, Hudson C. A prototype hyperspectral system with a tunable laser source for retinal vessel imaging. Invest Ophthalmol Vis Sci. 2013 Aug 01; 54(8):5163-8. PMID: 23821191.
    View in: PubMed
  34. Shahidi AM, Patel SR, Flanagan JG, Hudson C. Regional variation in human retinal vessel oxygen saturation. Exp Eye Res. 2013 Aug; 113:143-7. PMID: 23791637.
    View in: PubMed
  35. Preitner N, Quan J, Flanagan JG. This message will self-destruct: NMD regulates axon guidance. Cell. 2013 Jun 06; 153(6):1185-7. PMID: 23746834; PMCID: PMC3703776.
  36. Murray SC, Flanagan J, Popova OB, Chiu W, Ludtke SJ, Serysheva II. Validation of cryo-EM structure of IP3R1 channel. Structure. 2013 Jun 04; 21(6):900-9. PMID: 23707684; PMCID: PMC3696195.
  37. Sigal IA, Flanagan JG, Lathrop KL, Tertinegg I, Bilonick R. Human lamina cribrosa insertion and age. Invest Ophthalmol Vis Sci. 2012 Oct 03; 53(11):6870-9. PMID: 22956611; PMCID: PMC3466065.
  38. Rogers R, Dharsee M, Ackloo S, Flanagan JG. Proteomics analyses of activated human optic nerve head lamina cribrosa cells following biomechanical strain. Invest Ophthalmol Vis Sci. 2012 Jun 20; 53(7):3806-16. PMID: 22589438.
    View in: PubMed
  39. Preitner N, Flanagan JG. Axonal mRNA translation: an unexpected link to axon survival and the mitochondrion. Neuron. 2012 Feb 23; 73(4):629-31. PMID: 22365539; PMCID: PMC3712866.
  40. Mammo ZN, Flanagan JG, James DF, Trope GE. Generic versus brand-name North American topical glaucoma drops. Can J Ophthalmol. 2012 Feb; 47(1):55-61. PMID: 22333853.
    View in: PubMed
  41. Rogers RS, Dharsee M, Ackloo S, Sivak JM, Flanagan JG. Proteomics analyses of human optic nerve head astrocytes following biomechanical strain. Mol Cell Proteomics. 2012 Feb; 11(2):M111.012302. PMID: 22126795; PMCID: PMC3277762.
  42. Hancock ML, Nowakowski DW, Role LW, Talmage DA, Flanagan JG. Type III neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery. Development. 2011 Nov; 138(22):4887-98. PMID: 22028026; PMCID: PMC3201659.
  43. Puzyeyeva O, Lam WC, Flanagan JG, Brent MH, Devenyi RG, Mandelcorn MS, Wong T, Hudson C. High-resolution optical coherence tomography retinal imaging: a case series illustrating potential and limitations. J Ophthalmol. 2011; 2011:764183. PMID: 21969910; PMCID: PMC3182576.
  44. Tanas MR, Sboner A, Oliveira AM, Erickson-Johnson MR, Hespelt J, Hanwright PJ, Flanagan J, Luo Y, Fenwick K, Natrajan R, Mitsopoulos C, Zvelebil M, Hoch BL, Weiss SW, Debiec-Rychter M, Sciot R, West RB, Lazar AJ, Ashworth A, Reis-Filho JS, Lord CJ, Gerstein MB, Rubin MA, Rubin BP. Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma. Sci Transl Med. 2011 Aug 31; 3(98):98ra82. PMID: 21885404.
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  45. Anraku A, Jin YP, Butty Z, Jinapriya D, Alasbali T, Mammo Z, Flanagan JG, Trope GE. The Toronto epidemiology glaucoma survey: a pilot study. Can J Ophthalmol. 2011 Aug; 46(4):352-7. PMID: 21816256.
    View in: PubMed
  46. Rootman DB, Howarth D, Kerr JQ, Flanagan JG, Trope GE, Buys YM. Sterile single use cover for the G-probe Transscleral Cyclodiode. J Glaucoma. 2011 Apr-May; 20(4):260-5. PMID: 20577100.
    View in: PubMed
  47. Coles CH, Shen Y, Tenney AP, Siebold C, Sutton GC, Lu W, Gallagher JT, Jones EY, Flanagan JG, Aricescu AR. Proteoglycan-specific molecular switch for RPTPs clustering and neuronal extension. Science. 2011 Apr 22; 332(6028):484-8. PMID: 21454754.
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  48. Sehi M, Flanagan JG, Zeng L, Cook RJ, Trope GE. The association between diurnal variation of optic nerve head topography and intraocular pressure and ocular perfusion pressure in untreated primary open-angle glaucoma. J Glaucoma. 2011 Jan; 20(1):44-50. PMID: 20436368.
    View in: PubMed
  49. Venkataraman ST, Flanagan JG, Hudson C. Vascular reactivity of optic nerve head and retinal blood vessels in glaucoma--a review. Microcirculation. 2010 Oct; 17(7):568-81. PMID: 21040122.
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  50. Norman RE, Flanagan JG, Sigal IA, Rausch SM, Tertinegg I, Ethier CR. Finite element modeling of the human sclera: influence on optic nerve head biomechanics and connections with glaucoma. Exp Eye Res. 2011 Jul; 93(1):4-12. PMID: 20883693.
    View in: PubMed
  51. Eilaghi A, Flanagan JG, Tertinegg I, Simmons CA, Wayne Brodland G, Ross Ethier C. Biaxial mechanical testing of human sclera. J Biomech. 2010 Jun 18; 43(9):1696-701. PMID: 20399430.
    View in: PubMed
  52. Tcherkezian J, Brittis PA, Thomas F, Roux PP, Flanagan JG. Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation. Cell. 2010 May 14; 141(4):632-44. PMID: 20434207; PMCID: PMC2881594.
  53. Buys YM, Alasbali T, Jin YP, Smith M, Gouws P, Geffen N, Flanagan JG, Shapiro CM, Trope GE. Effect of sleeping in a head-up position on intraocular pressure in patients with glaucoma. Ophthalmology. 2010 Jul; 117(7):1348-51. PMID: 20188421.
    View in: PubMed
  54. Eilaghi A, Flanagan JG, Simmons CA, Ethier CR. Effects of scleral stiffness properties on optic nerve head biomechanics. Ann Biomed Eng. 2010 Apr; 38(4):1586-92. PMID: 20039133.
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  55. Norman RE, Flanagan JG, Rausch SM, Sigal IA, Tertinegg I, Eilaghi A, Portnoy S, Sled JG, Ethier CR. Dimensions of the human sclera: Thickness measurement and regional changes with axial length. Exp Eye Res. 2010 Feb; 90(2):277-84. PMID: 19900442.
    View in: PubMed
  56. Venkataraman ST, Hudson C, Rachmiel R, Buys YM, Markowitz SN, Fisher JA, Trope GE, Flanagan JG. Retinal arteriolar vascular reactivity in untreated and progressive primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 2010 Apr; 51(4):2043-50. PMID: 19907031.
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  57. Shen Y, Tenney AP, Busch SA, Horn KP, Cuascut FX, Liu K, He Z, Silver J, Flanagan JG. PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. Science. 2009 Oct 23; 326(5952):592-6. PMID: 19833921; PMCID: PMC2811318.
  58. Keech A, Flanagan J, Simpson T, Jones L. Tear meniscus height determination using the OCT2 and the RTVue-100. Optom Vis Sci. 2009 Oct; 86(10):1154-9. PMID: 19741561.
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  59. Sigal IA, Flanagan JG, Tertinegg I, Ethier CR. 3D morphometry of the human optic nerve head. Exp Eye Res. 2010 Jan; 90(1):70-80. PMID: 19772858.
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  60. Eilaghi A, Flanagan JG, Brodland GW, Ethier CR. Strain uniformity in biaxial specimens is highly sensitive to attachment details. J Biomech Eng. 2009 Sep; 131(9):091003. PMID: 19725692.
    View in: PubMed
  61. Chen Y, Mohammadi M, Flanagan JG. Graded levels of FGF protein span the midbrain and can instruct graded induction and repression of neural mapping labels. Neuron. 2009 Jun 25; 62(6):773-80. PMID: 19555646; PMCID: PMC2850284.
  62. Lundmark PO, Trope GE, Shapiro CM, Flanagan JG. Depressive symptomatology in tertiary-care glaucoma patients. Can J Ophthalmol. 2009 Apr; 44(2):198-204. PMID: 19491956.
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  63. Baba A, Akagi K, Takayanagi M, Flanagan JG, Kobayashi T, Hattori M. Fyn tyrosine kinase regulates the surface expression of glycosylphosphatidylinositol-linked ephrin via the modulation of sphingomyelin metabolism. J Biol Chem. 2009 Apr 03; 284(14):9206-14. PMID: 19181669; PMCID: PMC2666573.
  64. Rachmiel R, Trope GE, Buys YM, Flanagan JG, Chipman ML. Intermediate-term outcome and success of superior versus inferior Ahmed Glaucoma Valve implantation. J Glaucoma. 2008 Oct-Nov; 17(7):584-90. PMID: 18854738.
    View in: PubMed
  65. Venkataraman ST, Hudson C, Fisher JA, Rodrigues L, Mardimae A, Flanagan JG. Retinal arteriolar and capillary vascular reactivity in response to isoxic hypercapnia. Exp Eye Res. 2008 Dec; 87(6):535-42. PMID: 18840429.
    View in: PubMed
  66. Alasbali T, Smith M, Geffen N, Trope GE, Flanagan JG, Jin Y, Buys YM. Discrepancy between results and abstract conclusions in industry- vs nonindustry-funded studies comparing topical prostaglandins. Am J Ophthalmol. 2009 Jan; 147(1):33-38.e2. PMID: 18760766.
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  67. Rachmiel R, Trope GE, Buys YM, Flanagan JG, Chipman ML. Ahmed glaucoma valve implantation in uveitic glaucoma versus open-angle glaucoma patients. Can J Ophthalmol. 2008 Aug; 43(4):462-7. PMID: 18711462.
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  68. Qiu R, Wang X, Davy A, Wu C, Murai K, Zhang H, Flanagan JG, Soriano P, Lu Q. Regulation of neural progenitor cell state by ephrin-B. J Cell Biol. 2008 Jun 16; 181(6):973-83. PMID: 18541704; PMCID: PMC2426945.
  69. Goren D, Flanagan JG. Is flicker-defined form (FDF) dependent on the contour? J Vis. 2008 Apr 22; 8(4):15.1-11. PMID: 18484854.
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  70. Sigal IA, Flanagan JG, Tertinegg I, Ethier CR. Modeling individual-specific human optic nerve head biomechanics. Part I: IOP-induced deformations and influence of geometry. Biomech Model Mechanobiol. 2009 Apr; 8(2):85-98. PMID: 18309526.
    View in: PubMed
  71. Sigal IA, Flanagan JG, Tertinegg I, Ethier CR. Modeling individual-specific human optic nerve head biomechanics. Part II: influence of material properties. Biomech Model Mechanobiol. 2009 Apr; 8(2):99-109. PMID: 18301933.
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  72. Osterfield M, Egelund R, Young LM, Flanagan JG. Interaction of amyloid precursor protein with contactins and NgCAM in the retinotectal system. Development. 2008 Mar; 135(6):1189-99. PMID: 18272596.
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  73. Luo L, Flanagan JG. Development of continuous and discrete neural maps. Neuron. 2007 Oct 25; 56(2):284-300. PMID: 17964246.
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  74. Chew HF, Markowitz SN, Flanagan J, Buys YM. The effect of pupil dilation on driving vision in Canada. Can J Ophthalmol. 2007 Aug; 42(4):585-91. PMID: 17641702.
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  75. Sigal IA, Flanagan JG, Tertinegg I, Ethier CR. Predicted extension, compression and shearing of optic nerve head tissues. Exp Eye Res. 2007 Sep; 85(3):312-22. PMID: 17624325.
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  76. Duench S, Simpson T, Jones LW, Flanagan JG, Fonn D. Assessment of variation in bulbar conjunctival redness, temperature, and blood flow. Optom Vis Sci. 2007 Jun; 84(6):511-6. PMID: 17568321.
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  77. Dhillon S, Shapiro CM, Flanagan J. Sleep-disordered breathing and effects on ocular health. Can J Ophthalmol. 2007 Apr; 42(2):238-43. PMID: 17392846.
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  78. Kourkoutas D, Buys YM, Flanagan JG, Hatch WV, Balian C, Trope GE. Comparison of glaucoma progression evaluated with Heidelberg retina tomograph II versus optic nerve head stereophotographs. Can J Ophthalmol. 2007 Feb; 42(1):82-8. PMID: 17361246.
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  79. Ikado K, Abe K, Abe K, Adachi I, Aihara H, Akai K, Akemoto M, Anipko D, Arinstein K, Aulchenko V, Aushev T, Aziz T, Bakich AM, Balagura V, Barbero M, Bay A, Bedny I, Belous K, Bitenc U, Bizjak I, Bondar A, Bozek A, Bracko M, Browder TE, Chang P, Chen A, Chen WT, Choi Y, Cole S, Dalseno J, Danilov M, Dash M, Eidelman S, Epifanov D, Flanagan J, Fratina S, Furukawa K, Gabyshev N, Gershon T, Go A, Gokhroo G, Golob B, Gorisek A, Ha H, Haba J, Hara K, Hara T, Hastings NC, Hayasaka K, Hayashii H, Hazumi M, Hinz L, Hokuue T, Hoshi Y, Hou S, Hou WS, Iida N, Iijima T, Imoto A, Inami K, Ishikawa A, Ishino H, Itoh R, Iwasaki M, Iwasaki Y, Kamitani T, Kang JH, Kataoka SU, Katayama N, Kawai H, Kawasaki T, Kichimi H, Kikutani E, Kim HJ, Kim HO, Kinoshita K, Koiso H, Korpar S, Krizan P, Krokovny P, Kulasiri R, Kumar R, Kuo CC, Kuzmin A, Kwon YJ, Lange JS, Leder G, Lee J, Lesiak T, Limosani A, Lin SW, Liventsev D, Marlow D, Matsumoto T, Matyja A, McOnie S, Michizono S, Mimashi T, Mitaroff W, Miyabayashi K, Miyata H, Miyazaki Y, Mizuk R, Nagamine T, Nakamura I, Nakamura TT, Nakano E, Nakao M, Nishida S, Nitoh O, Noguchi S, Nozaki T, Ogawa S, Ogawa Y, Ohmi K, Ohshima T, Ohuchi N, Oide K, Okabe T, Okuno S, Olsen SL, Onuki Y, Ostrowicz W, Ozaki H, Pakhlov P, Park CW, Park H, Pestotnik R, Piilonen LE, Poluektov A, Rozanska M, Sakai Y, Schietinger T, Schneider O, Schwanda C, Senyo K, Sevior ME, Shapkin M, Shibuya H, Shidara T, Shwartz B, Sidorov V, Sokolov A, Somov A, Stanic S, Staric M, Stoeck H, Sumisawa K, Sumiyoshi T, Suzuki S, Tajima O, Takasaki F, Tamai K, Tamura N, Tanaka M, Tawada M, Taylor GN, Teramoto Y, Tian XC, Trabelsi K, Tsuboyama T, Tsukamoto T, Uehara S, Uglov T, Ueno K, Unno Y, Uno S, Usov Y, Varner G, Villa S, Wang CC, Wang CH, Watanabe Y, Won E, Yabsley BD, Yamaguchi A, Yamashita Y, Yamauchi M, Yoshida M, Yusa Y, Zhang LM, Zhang ZP, Zhilich V, Zürcher D. Evidence of the purely leptonic decay B- --> tau- nu(tau). Phys Rev Lett. 2006 Dec 22; 97(25):251802. PMID: 17280341.
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  80. Chen Y, Flanagan JG. Follow your nose: axon pathfinding in olfactory map formation. Cell. 2006 Dec 01; 127(5):881-4. PMID: 17129775.
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  81. Venkataraman ST, Hudson C, Fisher JA, Flanagan JG. Novel methodology to comprehensively assess retinal arteriolar vascular reactivity to hypercapnia. Microvasc Res. 2006 Nov; 72(3):101-7. PMID: 16926032.
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  82. Kisilevsky M, Hudson C, Flanagan JG, Nrusimhadevara RK, Guan K, Wong T, Mandelcorn M, Lam WC, Devenyi RG. Agreement of the Heidelberg Retina Tomograph II macula edema module with fundus biomicroscopy in diabetic maculopathy. Arch Ophthalmol. 2006 Mar; 124(3):337-42. PMID: 16534053.
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  83. Guan K, Hudson C, Wong T, Kisilevsky M, Nrusimhadevara RK, Lam WC, Mandelcorn M, Devenyi RG, Flanagan JG. Retinal hemodynamics in early diabetic macular edema. Diabetes. 2006 Mar; 55(3):813-8. PMID: 16505248.
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  158. Lark MW, Bayne EK, Flanagan J, Harper CF, Hoerrner LA, Hutchinson NI, Singer II, Donatelli SA, Weidner JR, Williams HR, Mumford RA, Lohmander LS. Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints. J Clin Invest. 1997 Jul 01; 100(1):93-106. PMID: 9202061; PMCID: PMC508169.
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  160. Prokopich CL, Flanagan JG. Gonioscopy: evaluation of the anterior chamber angle. Part II. Ophthalmic Physiol Opt. 1997 Mar; 17 Suppl 1:S9-13. PMID: 9219674.
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  161. Hudson C, Charles SJ, Flanagan JG, Brahma AK, Turner GS, McLeod D. Objective morphological assessment of macular hole surgery by scanning laser tomography. Br J Ophthalmol. 1997 Feb; 81(2):107-16. PMID: 9059243; PMCID: PMC1722126.
  162. Zhang JH, Cerretti DP, Yu T, Flanagan JG, Zhou R. Detection of ligands in regions anatomically connected to neurons expressing the Eph receptor Bsk: potential roles in neuron-target interaction. J Neurosci. 1996 Nov 15; 16(22):7182-92. PMID: 8929427.
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  163. Nakamoto M, Cheng HJ, Friedman GC, McLaughlin T, Hansen MJ, Yoon CH, O'Leary DD, Flanagan JG. Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo. Cell. 1996 Sep 06; 86(5):755-66. PMID: 8797822.
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  164. Prokopich CL, Flanagan JG. Gonioscopy: evaluation of the anterior chamber angle. Part I. Ophthalmic Physiol Opt. 1996 Sep; 16 Suppl 2:S39-42. PMID: 9398919.
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  165. Lorenz U, Bergemann AD, Steinberg HN, Flanagan JG, Li X, Galli SJ, Neel BG. Genetic analysis reveals cell type-specific regulation of receptor tyrosine kinase c-Kit by the protein tyrosine phosphatase SHP1. J Exp Med. 1996 Sep 01; 184(3):1111-26. PMID: 9064328; PMCID: PMC2192792.
  166. Chiang MK, Flanagan JG. PTP-NP, a new member of the receptor protein tyrosine phosphatase family, implicated in development of nervous system and pancreatic endocrine cells. Development. 1996 Jul; 122(7):2239-50. PMID: 8681804.
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  167. Hosking SL, Flanagan JG. Prospective study design for the Heidelberg Retina Tomograph: the effect of change in focus setting. Graefes Arch Clin Exp Ophthalmol. 1996 May; 234(5):306-10. PMID: 8740251.
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  168. Cao Y, Chen H, Zhou L, Chiang MK, Anand-Apte B, Weatherbee JA, Wang Y, Fang F, Flanagan JG, Tsang ML. Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR. J Biol Chem. 1996 Feb 09; 271(6):3154-62. PMID: 8621715.
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  169. Brambilla R, Brückner K, Orioli D, Bergemann AD, Flanagan JG, Klein R. Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors. Mol Cell Neurosci. 1996; 8(2-3):199-209. PMID: 8918835.
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  170. Hudson C, Shah S, Flanagan JG, Brahma A, Ansons A. Scanning laser tomography in benign intracranial hypertension. Lancet. 1995 Nov 25; 346(8987):1435. PMID: 7475857.
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  171. Elliott DB, Patla AE, Flanagan JG, Spaulding S, Rietdyk S, Strong G, Brown S. The Waterloo Vision and Mobility Study: postural control strategies in subjects with ARM. Ophthalmic Physiol Opt. 1995 Nov; 15(6):553-9. PMID: 8594526.
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  172. Bergemann AD, Cheng HJ, Brambilla R, Klein R, Flanagan JG. ELF-2, a new member of the Eph ligand family, is segmentally expressed in mouse embryos in the region of the hindbrain and newly forming somites. Mol Cell Biol. 1995 Sep; 15(9):4921-9. PMID: 7651410; PMCID: PMC230738.
  173. Flanagan JG, Prokopich CL. Indirect fundus biomicroscopy. Ophthalmic Physiol Opt. 1995 Sep; 15 Suppl 2:S38-41. PMID: 8532343.
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  174. Cheng HJ, Nakamoto M, Bergemann AD, Flanagan JG. Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell. 1995 Aug 11; 82(3):371-81. PMID: 7634327.
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  175. Brambilla R, Schnapp A, Casagranda F, Labrador JP, Bergemann AD, Flanagan JG, Pasquale EB, Klein R. Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases. EMBO J. 1995 Jul 03; 14(13):3116-26. PMID: 7621826; PMCID: PMC394373.
  176. Chiang MK, Flanagan JG. Interactions between the Flk-1 receptor, vascular endothelial growth factor, and cell surface proteoglycan identified with a soluble receptor reagent. Growth Factors. 1995; 12(1):1-10. PMID: 8527158.
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  177. Spaulding SJ, Patla AE, Elliott DB, Flanagan J, Rietdyk S, Brown S. Waterloo Vision and Mobility Study: gait adaptations to altered surfaces in individuals with age-related maculopathy. Optom Vis Sci. 1994 Dec; 71(12):770-7. PMID: 7898884.
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  178. Cheng HJ, Flanagan JG. Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases. Cell. 1994 Oct 07; 79(1):157-68. PMID: 7522971.
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  179. Cheng HJ, Flanagan JG. Transmembrane kit ligand cleavage does not require a signal in the cytoplasmic domain and occurs at a site dependent on spacing from the membrane. Mol Biol Cell. 1994 Sep; 5(9):943-53. PMID: 7531036; PMCID: PMC301118.
  180. Elliott DB, Fonn D, Flanagan J, Doughty M. Relative sensitivity of clinical tests to hydrophilic lens-induced corneal thickness changes. Optom Vis Sci. 1993 Dec; 70(12):1044-8. PMID: 8115128.
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  181. Flanagan JG, Moss ID, Wild JM, Hudson C, Prokopich L, Whitaker D, O'Neill EC. Evaluation of FASTPAC: a new strategy for threshold estimation with the Humphrey Field Analyser. Graefes Arch Clin Exp Ophthalmol. 1993 Aug; 231(8):465-9. PMID: 8224946.
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  182. Flanagan JG, Wild JM, Trope GE. The visual field indices in primary open-angle glaucoma. Invest Ophthalmol Vis Sci. 1993 Jun; 34(7):2266-74. PMID: 8505208.
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  183. Flanagan JG, Wild JM, Trope GE. Evaluation of FASTPAC, a new strategy for threshold estimation with the Humphrey Field Analyzer, in a glaucomatous population. Ophthalmology. 1993 Jun; 100(6):949-54. PMID: 8510911.
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  184. Wild JM, Hussey MK, Flanagan JG, Trope GE. Pointwise topographical and longitudinal modeling of the visual field in glaucoma. Invest Ophthalmol Vis Sci. 1993 May; 34(6):1907-16. PMID: 8491543.
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  185. Ornitz DM, Yayon A, Flanagan JG, Svahn CM, Levi E, Leder P. Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Mol Cell Biol. 1992 Jan; 12(1):240-7. PMID: 1309590; PMCID: PMC364088.
  186. Flanagan JG, Chan DC, Leder P. Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant. Cell. 1991 Mar 08; 64(5):1025-35. PMID: 1705866.
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  187. Kothe AC, Flanagan J, Trevino RC. True posterior ischemic optic neuropathy associated with herpes zoster ophthalmicus. Optom Vis Sci. 1990 Nov; 67(11):845-9. PMID: 2250894.
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  188. Flanagan JG, Leder P. The kit ligand: a cell surface molecule altered in steel mutant fibroblasts. Cell. 1990 Oct 05; 63(1):185-94. PMID: 1698555.
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  189. Flanagan JG, Kothe AC. Intracranial meningioma: an exercise in differential diagnosis. Ophthalmic Physiol Opt. 1990 Apr; 10(2):205-10. PMID: 2371068.
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  190. Kothe AC, Lovasik JV, Pace R, Hrynchak PK, Flanagan JG. Visual and neural function in Leber's optic neuropathy. Optom Vis Sci. 1990 Feb; 67(2):138-47. PMID: 2336254.
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  191. Styles T, Flanagan JG. Meridional differences in temporal response characteristics. Ophthalmic Physiol Opt. 1989 Oct; 9(4):405-10. PMID: 2631007.
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  192. Jakobiec FA, Rini F, Char D, Orcutt J, Rootman J, Baylis H, Flanagan J. Primary liposarcoma of the orbit. Problems in the diagnosis and management of five cases. Ophthalmology. 1989 Feb; 96(2):180-91. PMID: 2704536.
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  193. Flanagan JG, Leder P. neu protooncogene fused to an immunoglobulin heavy chain gene requires immunoglobulin light chain for cell surface expression and oncogenic transformation. Proc Natl Acad Sci U S A. 1988 Nov; 85(21):8057-61. PMID: 2903500; PMCID: PMC282353.
  194. Flanagan JG, Wild JM, Wood JM. Stimulus configuration and the format of the normal sensitivity gradient. Doc Ophthalmol. 1988 Aug; 69(4):371-83. PMID: 3060338.
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  195. Flanagan JG, Harding GF. Multi-channel visual evoked potentials in early compressive lesions of the chiasm. Doc Ophthalmol. 1988 Jul; 69(3):271-81. PMID: 3168727.
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  196. Wild JM, Wood JM, Flanagan JG, Good PA, Crews SJ. The interpretation of the differential threshold in the central visual field. Doc Ophthalmol. 1986 Feb 28; 62(2):191-202. PMID: 3956369.
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  197. Barnes DA, Wild JM, Flanagan JG, Good PA, Crews SJ. Manipulation of sensitivity in visual field investigation. Doc Ophthalmol. 1985 Jun 30; 59(4):301-8. PMID: 4028920.
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  198. Clement RA, Flanagan JG, Harding GF. Source derivation of the visual evoked response to pattern reversal stimulation. Electroencephalogr Clin Neurophysiol. 1985 Jan; 62(1):74-6. PMID: 2578380.
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  199. Wild JM, Flanagan JG, Barnes DA, Gilmartin BA, Good PA, Crews SJ. The qualitative comparative analysis of the visual field using computer assisted, semi-automated and manual instrumentation: II. Statistical analysis. Doc Ophthalmol. 1984 Dec 15; 58(4):325-40. PMID: 6525935.
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  200. Flanagan JG, Wild JM, Barnes DA, Gilmartin BA, Good PA, Crews SJ. The qualitative comparative analysis of the visual field using computer assisted, semi-automated and manual instrumentation: III. Clinical analysis. Doc Ophthalmol. 1984 Dec 15; 58(4):341-50. PMID: 6549288.
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  201. Flanagan JG, Lefranc MP, Rabbitts TH. Mechanisms of divergence and convergence of the human immunoglobulin alpha 1 and alpha 2 constant region gene sequences. Cell. 1984 Mar; 36(3):681-8. PMID: 6421489.
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  202. Ruchman MC, Flanagan J. Cavernous hemangiomas of the orbit. Ophthalmology. 1983 Nov; 90(11):1328-36. PMID: 6664672.
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  203. Nowinski T, Flanagan J, Ruchman M. Lacrimal gland enlargement in familial sarcoidosis. Ophthalmology. 1983 Aug; 90(8):909-13. PMID: 6634073.
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  204. Hornblass A, Jakobiec FA, Bosniak S, Flanagan J. The diagnosis and management of epithelial tumors of the lacrimal sac. Ophthalmology. 1980 Jun; 87(6):476-90. PMID: 7413136.
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