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Marc Alan Pfeffer, M.D., PH.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P20HL101866 (PFEFFER, MARC ALAN) Apr 1, 2010 - Mar 31, 2012
    NIH/NHLBI
    Cardiac progenitor cell therapy for advanced ischemic cardiomyopathy.
    Role: Principal Investigator
  2. P50HL036568 (WILLIAMS, GORDON H) Dec 1, 1985 - Nov 30, 1991
    NIH/NHLBI
    SPECIALIZED CENTER OF RESEARCH IN HYPERTENSION
    Role: Principal Investigator
  3. R01HL036074 (PFEFFER, MARC A) Sep 1, 1985 - Aug 31, 1987
    NIH/NHLBI
    CARDIAC HYPERTROPHY AND FAILURE
    Role: Principal Investigator
  4. M01RR002635 (GOTTLIEB, GARY L) Dec 1, 1984 - Mar 31, 2010
    NIH/NCRR
    General Clinical Research Center
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Beldhuis IE, Myhre PL, Claggett B, Damman K, Fang JC, Lewis EF, O'Meara E, Pitt B, Shah SJ, Voors AA, Pfeffer MA, Solomon SD, Desai AS. Efficacy and Safety of Spironolactone in Patients With HFpEF and Chronic Kidney Disease. JACC Heart Fail. 2019 Jan; 7(1):25-32. PMID: 30606484.
    View in: PubMed
  2. Pfeffer MA, Maggioni AP. Judgement over an arbitrary line. Eur Heart J. 2018 Dec 21; 39(48):4266-4268. PMID: 30395197.
    View in: PubMed
  3. Mc Causland FR, Claggett B, Burdmann EA, Chertow GM, Cooper ME, Eckardt KU, Ivanovich P, Levey AS, Lewis EF, McGill JB, McMurray JJV, Parfrey P, Parving HH, Remuzzi G, Singh AK, Solomon SD, Toto RD, Pfeffer MA. Treatment of Anemia With Darbepoetin Prior to Dialysis Initiation and Clinical Outcomes: Analyses From the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT). Am J Kidney Dis. 2018 Dec 19. PMID: 30578152.
    View in: PubMed
  4. Selvaraj S, Claggett B, Shah SJ, Anand I, Rouleau JL, O'Meara E, Desai AS, Lewis EF, Pitt B, Sweitzer NK, Fang JC, Pfeffer MA, Solomon SD. Prognostic Value of Albuminuria and Influence of Spironolactone in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2018 Nov; 11(11):e005288. PMID: 30571191.
    View in: PubMed
  5. Myhre PL, O'Meara E, Claggett BL, de Denus S, Jarolim P, Anand IS, Beldhuis IE, Fleg JL, Lewis E, Pitt B, Rouleau JL, Solomon SD, Pfeffer MA, Desai AS. Cardiac Troponin I and Risk of Cardiac Events in Patients With Heart Failure and Preserved Ejection Fraction. Circ Heart Fail. 2018 Nov; 11(11):e005312. PMID: 30571192.
    View in: PubMed
  6. Tian L, Jiang F, Hasegawa T, Uno H, Pfeffer M, Wei LJ. Moving beyond the conventional stratified analysis to estimate an overall treatment efficacy with the data from a comparative randomized clinical study. Stat Med. 2018 Oct 23. PMID: 30352486.
    View in: PubMed
  7. Pfeffer MA, Tardif JC. COMMANDER HF - A Trial and an Answer. N Engl J Med. 2018 10 04; 379(14):1372-1374. PMID: 30281980.
    View in: PubMed
  8. Myhre PL, Vaduganathan M, Claggett BL, Anand IS, Sweitzer NK, Fang JC, O'Meara E, Shah SJ, Desai AS, Lewis EF, Rouleau J, Pitt B, Pfeffer MA, Solomon SD. Association of Natriuretic Peptides With Cardiovascular Prognosis in Heart Failure With Preserved Ejection Fraction: Secondary Analysis of the TOPCAT Randomized Clinical Trial. JAMA Cardiol. 2018 Oct 01; 3(10):1000-1005. PMID: 30140899.
    View in: PubMed
  9. Rossello X, Ferreira JP, McMurray JJ, Aguilar D, Pfeffer MA, Pitt B, Dickstein K, Girerd N, Rossignol P, Zannad F. Impact of insulin-treated diabetes on cardiovascular outcomes following high-risk myocardial infarction. Eur Heart J Acute Cardiovasc Care. 2018 Sep 27; 2048872618803701. PMID: 30259764.
    View in: PubMed
  10. Sanders NA, Supiano MA, Lewis EF, Liu J, Claggett B, Pfeffer MA, Desai AS, Sweitzer NK, Solomon SD, Fang JC. The frailty syndrome and outcomes in the TOPCAT trial. Eur J Heart Fail. 2018 Nov; 20(11):1570-1577. PMID: 30225878.
    View in: PubMed
  11. Pfeffer MA, Dubé MP, Tardif JC. Randomized Clinical Trial Needed to Confirm Whether Dalcetrapib Improves Outcomes for Specific ADCY9 Genotype. JAMA Cardiol. 2018 Sep 01; 3(9):897. PMID: 30090919.
    View in: PubMed
  12. Claggett B, Pocock S, Wei LJ, Pfeffer MA, McMurray JJV, Solomon SD. Comparison of Time-to-First Event and Recurrent-Event Methods in Randomized Clinical Trials. Circulation. 2018 Aug 07; 138(6):570-577. PMID: 29588314.
    View in: PubMed
  13. Weiner DE, Park M, Tighiouart H, Joseph AA, Carpenter MA, Goyal N, House AA, Hsu CY, Ix JH, Jacques PF, Kew CE, Kim SJ, Kusek JW, Pesavento TE, Pfeffer MA, Smith SR, Weir MR, Levey AS, Bostom AG. Albuminuria and Allograft Failure, Cardiovascular Disease Events, and All-Cause Death in Stable Kidney Transplant Recipients: A Cohort Analysis of the FAVORIT Trial. Am J Kidney Dis. 2019 Jan; 73(1):51-61. PMID: 30037726.
    View in: PubMed
  14. Bostom A, Pasch A, Madsen T, Roberts MB, Franceschini N, Steubl D, Garimella PS, Ix JH, Tuttle KR, Ivanova A, Shireman T, Gohh R, Merhi B, Jarolim P, Kusek JW, Pfeffer MA, Liu S, Eaton CB. Serum Calcification Propensity and Fetuin-A: Biomarkers of Cardiovascular Disease in Kidney Transplant Recipients. Am J Nephrol. 2018; 48(1):21-31. PMID: 29996127.
    View in: PubMed
  15. Cikes M, Claggett B, Shah AM, Desai AS, Lewis EF, Shah SJ, Anand IS, O'Meara E, Rouleau JL, Sweitzer NK, Fang JC, Saksena S, Pitt B, Pfeffer MA, Solomon SD. Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: The TOPCAT Trial. JACC Heart Fail. 2018 Aug; 6(8):689-697. PMID: 30007557.
    View in: PubMed
  16. Foster JG, Wood SK, Pfeffer MA, DeMets DL, Garber A, Hennekens CH. ASPIRIN FOR PRIMARY PREVENTION IN PATIENTS WITH TYPE 2 DIABETES. Endocr Pract. 2018 Oct 02; 24(10):925-927. PMID: 29975578.
    View in: PubMed
  17. Solomon SD, Rizkala AR, Lefkowitz MP, Shi VC, Gong J, Anavekar N, Anker SD, Arango JL, Arenas JL, Atar D, Ben-Gal T, Boytsov SA, Chen CH, Chopra VK, Cleland J, Comin-Colet J, Duengen HD, Echeverría Correa LE, Filippatos G, Flammer AJ, Galinier M, Godoy A, Goncalvesova E, Janssens S, Katova T, Køber L, Lelonek M, Linssen G, Lund LH, O'Meara E, Merkely B, Milicic D, Oh BH, Perrone SV, Ranjith N, Saito Y, Saraiva JF, Shah S, Seferovic PM, Senni M, Sibulo AS, Sim D, Sweitzer NK, Taurio J, Vinereanu D, Vrtovec B, Widimský J, Yilmaz MB, Zhou J, Zweiker R, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, Van Veldhuisen DJ, Zannad F, Zile MR, McMurray JJV. Baseline Characteristics of Patients With Heart Failure and Preserved Ejection Fraction in the PARAGON-HF Trial. Circ Heart Fail. 2018 Jul; 11(7):e004962. PMID: 29980595.
    View in: PubMed
  18. Pfeffer MA, Rutherford JD. Therapeutic Attenuation of Cardiac Remodeling After Acute Myocardial Infarction: A Conversation With Marc A. Pfeffer, MD, PhD. Circulation. 2018 Jun 05; 137(23):2430-2434. PMID: 29866772.
    View in: PubMed
  19. Mc Causland FR, Pfeffer MA. Implantable cardioverter defibrillators in chronic kidney disease. Nat Rev Nephrol. 2018 Jun; 14(6):357-358. PMID: 29651098.
    View in: PubMed
  20. Pung M, Robishaw J, Pfeffer MA, Hennekens CH. Prescription of Statins to Women Poses New Clinical Challenges. Am J Med. 2018 Oct; 131(10):1139-1140. PMID: 29679537.
    View in: PubMed
  21. Zhao L, Tian L, Claggett B, Pfeffer M, Kim DH, Solomon S, Wei LJ. Estimating Treatment Effect With Clinical Interpretation From a Comparative Clinical Trial With an End Point Subject to Competing Risks. JAMA Cardiol. 2018 Apr 01; 3(4):357-358. PMID: 29541747.
    View in: PubMed
  22. Desai AS, Liu J, Pfeffer MA, Claggett B, Fleg J, Lewis EF, McKinlay S, O'Meara E, Shah SJ, Sweitzer NK, Solomon S, Pitt B. Incident Hyperkalemia, Hypokalemia, and Clinical Outcomes During Spironolactone Treatment of Heart Failure With Preserved Ejection Fraction: Analysis of the TOPCAT Trial. J Card Fail. 2018 May; 24(5):313-320. PMID: 29572190.
    View in: PubMed
  23. Hicks KA, Mahaffey KW, Mehran R, Nissen SE, Wiviott SD, Dunn B, Solomon SD, Marler JR, Teerlink JR, Farb A, Morrow DA, Targum SL, Sila CA, Thanh Hai MT, Jaff MR, Joffe HV, Cutlip DE, Desai AS, Lewis EF, Gibson CM, Landray MJ, Lincoff AM, White CJ, Brooks SS, Rosenfield K, Domanski MJ, Lansky AJ, McMurray JJV, Tcheng JE, Steinhubl SR, Burton P, Mauri L, O'Connor CM, Pfeffer MA, Hung HMJ, Stockbridge NL, Chaitman BR, Temple RJ. 2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials. J Am Coll Cardiol. 2018 Mar 06; 71(9):1021-1034. PMID: 29495982.
    View in: PubMed
  24. Vaduganathan M, Claggett BL, Chatterjee NA, Anand IS, Sweitzer NK, Fang JC, O'Meara E, Shah SJ, Hegde SM, Desai AS, Lewis EF, Rouleau J, Pitt B, Pfeffer MA, Solomon SD. Sudden Death in Heart Failure With Preserved Ejection Fraction: A Competing Risks Analysis From the TOPCAT Trial. JACC Heart Fail. 2018 Aug; 6(8):653-661. PMID: 29501806.
    View in: PubMed
  25. Lewis EF, Claggett B, Shah AM, Liu J, Shah SJ, Anand I, O'Meara E, Sweitzer NK, Rouleau JL, Fang JC, Desai AS, Retta TM, Solomon SD, Heitner JF, Stamos TD, Boineau R, Pitt B, Pfeffer MA. Racial Differences in Characteristics and Outcomes of Patients With Heart Failure and Preserved Ejection Fraction in the Treatment of Preserved Cardiac Function Heart Failure Trial. Circ Heart Fail. 2018 Mar; 11(3):e004457. PMID: 29664406.
    View in: PubMed
  26. Hicks KA, Mahaffey KW, Mehran R, Nissen SE, Wiviott SD, Dunn B, Solomon SD, Marler JR, Teerlink JR, Farb A, Morrow DA, Targum SL, Sila CA, Hai MTT, Jaff MR, Joffe HV, Cutlip DE, Desai AS, Lewis EF, Gibson CM, Landray MJ, Lincoff AM, White CJ, Brooks SS, Rosenfield K, Domanski MJ, Lansky AJ, McMurray JJV, Tcheng JE, Steinhubl SR, Burton P, Mauri L, O'Connor CM, Pfeffer MA, Hung HMJ, Stockbridge NL, Chaitman BR, Temple RJ. 2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials. Circulation. 2018 Feb 27; 137(9):961-972. PMID: 29483172.
    View in: PubMed
  27. Ferreira JP, Girerd N, Gregson J, Latar I, Sharma A, Pfeffer MA, McMurray JJV, Abdul-Rahim AH, Pitt B, Dickstein K, Rossignol P, Zannad F. Stroke Risk in Patients With Reduced Ejection Fraction After Myocardial Infarction Without Atrial Fibrillation. J Am Coll Cardiol. 2018 Feb 20; 71(7):727-735. PMID: 29447733.
    View in: PubMed
  28. Lund LH, Claggett B, Liu J, Lam CS, Jhund PS, Rosano GM, Swedberg K, Yusuf S, Granger CB, Pfeffer MA, McMurray JJV, Solomon SD. Heart failure with mid-range ejection fraction in CHARM: characteristics, outcomes and effect of candesartan across the entire ejection fraction spectrum. Eur J Heart Fail. 2018 08; 20(8):1230-1239. PMID: 29431256.
    View in: PubMed
  29. Gitin A, Pfeffer MA, Hennekens CH. Editorial commentary: The lower the LDL the better but how and how much? Trends Cardiovasc Med. 2018 07; 28(5):355-356. PMID: 29428160.
    View in: PubMed
  30. van der Meer P, Grote Beverborg N, Pfeffer MA, Olson K, Anand IS, Westenbrink BD, McMurray JJV, Swedberg K, Young JB, Solomon SD, van Veldhuisen DJ. Hyporesponsiveness to Darbepoetin Alfa in Patients With Heart Failure and Anemia in the RED-HF Study (Reduction of Events by Darbepoetin Alfa in Heart Failure): Clinical and Prognostic Associations. Circ Heart Fail. 2018 Feb; 11(2):e004431. PMID: 29367268.
    View in: PubMed
  31. Ferreira JP, Duarte K, Pfeffer MA, McMurray JJV, Pitt B, Dickstein K, Zannad F, Rossignol P. Association between mean systolic and diastolic blood pressure throughout the follow-up and cardiovascular events in acute myocardial infarction patients with systolic dysfunction and/or heart failure: an analysis from the High-Risk Myocardial Infarction Database Initiative. Eur J Heart Fail. 2018 02; 20(2):323-331. PMID: 29314455.
    View in: PubMed
  32. Mc Causland FR, Claggett B, Pfeffer MA, Burdmann EA, Eckardt KU, Levey AS, McMurray JJV, Remuzzi G, Singh AK, Solomon SD, Toto RD, Parfrey P. Change in Hemoglobin Trajectory and Darbepoetin Dose Approaching End-Stage Renal Disease: Data from the Trial to Reduce Cardiovascular Events with Aranesp Therapy Trial. Am J Nephrol. 2017; 46(6):488-497. PMID: 29241199.
    View in: PubMed
  33. Pfeffer MA. Learning From Major Clinical Trials: Bending Without Breaking. Circulation. 2017 Dec 05; 136(23):2207-2209. PMID: 29203564.
    View in: PubMed
  34. Kristensen SL, Jhund PS, Lee MMY, Køber L, Solomon SD, Granger CB, Yusuf S, Pfeffer MA, Swedberg K, McMurray JJV. Prevalence of Prediabetes and Undiagnosed Diabetes in Patients with HFpEF and HFrEF and Associated Clinical Outcomes. Cardiovasc Drugs Ther. 2017 Dec; 31(5-6):545-549. PMID: 28948430.
    View in: PubMed
  35. Wolsk E, Claggett B, Køber L, Pocock S, Yusuf S, Swedberg K, McMurray JJV, Granger CB, Pfeffer MA, Solomon SD. Contribution of cardiac and extra-cardiac disease burden to risk of cardiovascular outcomes varies by ejection fraction in heart failure. Eur J Heart Fail. 2018 03; 20(3):504-510. PMID: 29193462.
    View in: PubMed
  36. Selvaraj S, Claggett B, Shah SJ, Anand I, Rouleau JL, Desai AS, Lewis EF, Pitt B, Sweitzer NK, Pfeffer MA, Solomon SD. Systolic blood pressure and cardiovascular outcomes in heart failure with preserved ejection fraction: an analysis of the TOPCAT trial. Eur J Heart Fail. 2018 03; 20(3):483-490. PMID: 29148144.
    View in: PubMed
  37. Seferovic JP, Pfeffer MA, Claggett B, Desai AS, de Zeeuw D, Haffner SM, McMurray JJV, Parving HH, Solomon SD, Chaturvedi N. Three-question set from Michigan Neuropathy Screening Instrument adds independent prognostic information on cardiovascular outcomes: analysis of ALTITUDE trial. Diabetologia. 2018 03; 61(3):581-588. PMID: 29098323.
    View in: PubMed
  38. Bajaj NS, Claggett B, Lewis EF, Desai AS, Fang JC, O'Meara E, Shah SJ, Sweitzer NK, Fleg JL, Pitt B, Rouleau JL, Finn P, Pfeffer MA, Solomon SD. Influence of ejection fraction on cause-specific mortality in heart failure with preserved ejection fraction. Eur J Heart Fail. 2018 04; 20(4):815-816. PMID: 29067754.
    View in: PubMed
  39. Wolsk E, Claggett B, Diaz R, Dickstein K, Gerstein HC, Køber L, Lawson FC, Lewis EF, Maggioni AP, McMurray JJV, Probstfield JL, Riddle MC, Solomon SD, Tardif JC, Pfeffer MA. Increases in Natriuretic Peptides Precede Heart Failure Hospitalization in Patients With a Recent Coronary Event and Type 2 Diabetes Mellitus. Circulation. 2017 Oct 17; 136(16):1560-1562. PMID: 29038210.
    View in: PubMed
  40. Vazir A, Claggett B, Pitt B, Anand I, Sweitzer N, Fang J, Fleg J, Rouleau J, Shah S, Pfeffer MA, Solomon SD. Prognostic Importance of Temporal Changes in Resting Heart Rate in Heart Failure and Preserved Ejection Fraction: From the TOPCAT Study. JACC Heart Fail. 2017 Nov; 5(11):782-791. PMID: 29032132.
    View in: PubMed
  41. Welsh P, Kou L, Yu C, Anand I, van Veldhuisen DJ, Maggioni AP, Desai AS, Solomon SD, Pfeffer MA, Cheng S, Gullestad L, Aukrust P, Ueland T, Swedberg K, Young JB, Kattan MW, Sattar N, McMurray JJV. Prognostic importance of emerging cardiac, inflammatory, and renal biomarkers in chronic heart failure patients with reduced ejection fraction and anaemia: RED-HF study. Eur J Heart Fail. 2018 02; 20(2):268-277. PMID: 28960777.
    View in: PubMed
  42. Platz E, Jhund PS, Claggett BL, Pfeffer MA, Swedberg K, Granger CB, Yusuf S, Solomon SD, McMurray JJ. Prevalence and prognostic importance of precipitating factors leading to heart failure hospitalization: recurrent hospitalizations and mortality. Eur J Heart Fail. 2018 02; 20(2):295-303. PMID: 28872259.
    View in: PubMed
  43. Kalil RS, Carpenter MA, Ivanova A, Gravens-Mueller L, John AA, Weir MR, Pesavento T, Bostom AG, Pfeffer MA, Hunsicker LG. Impact of Hyperuricemia on Long-term Outcomes of Kidney Transplantation: Analysis of the FAVORIT Study. Am J Kidney Dis. 2017 Dec; 70(6):762-769. PMID: 28801121.
    View in: PubMed
  44. Desai AS, Pfeffer MA. Beyond the P-value and the sound bite: learning from 'negative' clinical trials. Eur Heart J. 2017 Aug 07; 38(30):2349-2351. PMID: 28810671.
    View in: PubMed
  45. Baigent C, Herrington WG, Coresh J, Landray MJ, Levin A, Perkovic V, Pfeffer MA, Rossing P, Walsh M, Wanner C, Wheeler DC, Winkelmayer WC, McMurray JJV. Challenges in conducting clinical trials in nephrology: conclusions from a Kidney Disease-Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2017 08; 92(2):297-305. PMID: 28709600.
    View in: PubMed
  46. Solomon SD, Rizkala AR, Gong J, Wang W, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, Van Veldhuisen DJ, Zannad F, Zile MR, Desai AS, Shi VC, Lefkowitz MP, McMurray JJV. Angiotensin Receptor Neprilysin Inhibition in Heart Failure With Preserved Ejection Fraction: Rationale and Design of the PARAGON-HF Trial. JACC Heart Fail. 2017 07; 5(7):471-482. PMID: 28662936.
    View in: PubMed
  47. Hegde SM, Claggett B, Shah AM, Lewis EF, Anand I, Shah SJ, Sweitzer NK, Fang JC, Pitt B, Pfeffer MA, Solomon SD. Physical Activity and Prognosis in the TOPCAT Trial (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist). Circulation. 2017 Sep 12; 136(11):982-992. PMID: 28637881.
    View in: PubMed
  48. Charytan DM, Solomon SD, Ivanovich P, Remuzzi G, Cooper ME, McGill JB, Parving HH, Parfrey P, Singh AK, Burdmann EA, Levey AS, de Zeeuw D, Eckardt KU, McMurray JJV, Claggett B, Lewis EF, Pfeffer MA. ESRD After Heart Failure, Myocardial Infarction, or Stroke in Type 2 Diabetic Patients With CKD. Am J Kidney Dis. 2017 Oct; 70(4):522-531. PMID: 28599901.
    View in: PubMed
  49. Merhi B, Shireman T, Carpenter MA, Kusek JW, Jacques P, Pfeffer M, Rao M, Foster MC, Kim SJ, Pesavento TE, Smith SR, Kew CE, House AA, Gohh R, Weiner DE, Levey AS, Ix JH, Bostom A. Serum Phosphorus and Risk of Cardiovascular Disease, All-Cause Mortality, or Graft Failure in Kidney Transplant Recipients: An Ancillary Study of the FAVORIT Trial Cohort. Am J Kidney Dis. 2017 Sep; 70(3):377-385. PMID: 28579423.
    View in: PubMed
  50. Wolsk E, Claggett B, Pfeffer MA, Diaz R, Dickstein K, Gerstein HC, Lawson FC, Lewis EF, Maggioni AP, McMurray JJV, Probstfield JL, Riddle MC, Solomon SD, Tardif JC, Køber L. Role of B-Type Natriuretic Peptide and N-Terminal Prohormone BNP as Predictors of Cardiovascular Morbidity and Mortality in Patients With a Recent Coronary Event and Type 2 Diabetes Mellitus. J Am Heart Assoc. 2017 May 29; 6(6). PMID: 28554908.
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  51. Zannad F, Pfeffer MA, Bhatt DL, Bonds DE, Borer JS, Calvo-Rojas G, Fiore L, Lund LH, Madigan D, Maggioni AP, Meyers CM, Rosenberg Y, Simon T, Stough WG, Zalewski A, Zariffa N, Temple R. Streamlining cardiovascular clinical trials to improve efficiency and generalisability. Heart. 2017 08; 103(15):1156-1162. PMID: 28455296.
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  52. de Denus S, O'Meara E, Desai AS, Claggett B, Lewis EF, Leclair G, Jutras M, Lavoie J, Solomon SD, Pitt B, Pfeffer MA, Rouleau JL. Spironolactone Metabolites in TOPCAT - New Insights into Regional Variation. N Engl J Med. 2017 04 27; 376(17):1690-1692. PMID: 28445660.
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  53. Park M, Katz R, Shlipak MG, Weiner D, Tracy R, Jotwani V, Hughes-Austin J, Gabbai F, Hsu CY, Pfeffer M, Bansal N, Bostom A, Gutierrez O, Sarnak M, Levey A, Ix JH. Urinary Markers of Fibrosis and Risk of Cardiovascular Events and Death in Kidney Transplant Recipients: The FAVORIT Trial. Am J Transplant. 2017 Oct; 17(10):2640-2649. PMID: 28371433.
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  54. Rossignol P, Agarwal R, Canaud B, Charney A, Chatellier G, Craig JC, Cushman WC, Gansevoort RT, Fellström B, Garza D, Guzman N, Holtkamp FA, London GM, Massy ZA, Mebazaa A, Mol PGM, Pfeffer MA, Rosenberg Y, Ruilope LM, Seltzer J, Shah AM, Shah S, Singh B, Stefánsson BV, Stockbridge N, Stough WG, Thygesen K, Walsh M, Wanner C, Warnock DG, Wilcox CS, Wittes J, Pitt B, Thompson A, Zannad F. Cardiovascular outcome trials in patients with chronic kidney disease: challenges associated with selection of patients and endpoints. Eur Heart J. 2017 Apr 18. PMID: 28431138.
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  55. Anand IS, Claggett B, Liu J, Shah AM, Rector TS, Shah SJ, Desai AS, O'Meara E, Fleg JL, Pfeffer MA, Pitt B, Solomon SD. Interaction Between Spironolactone and Natriuretic Peptides in Patients With Heart Failure and Preserved Ejection Fraction: From the TOPCAT Trial. JACC Heart Fail. 2017 04; 5(4):241-252. PMID: 28359411.
    View in: PubMed
  56. Foster MC, Weiner DE, Bostom AG, Carpenter MA, Inker LA, Jarolim P, Joseph AA, Kusek JW, Pesavento T, Pfeffer MA, Rao M, Solomon SD, Levey AS. Filtration Markers, Cardiovascular Disease, Mortality, and Kidney Outcomes in Stable Kidney Transplant Recipients: The FAVORIT Trial. Am J Transplant. 2017 Sep; 17(9):2390-2399. PMID: 28257169.
    View in: PubMed
  57. Cowie MR, Filippatos GS, Alonso Garcia MLA, Anker SD, Baczynska A, Bloomfield DM, Borentain M, Bruins Slot K, Cronin M, Doevendans PA, El-Gazayerly A, Gimpelewicz C, Honarpour N, Janmohamed S, Janssen H, Kim AM, Lautsch D, Laws I, Lefkowitz M, Lopez-Sendon J, Lyon AR, Malik FI, McMurray JJV, Metra M, Figueroa Perez S, Pfeffer MA, Pocock SJ, Ponikowski P, Prasad K, Richard-Lordereau I, Roessig L, Rosano GMC, Sherman W, Stough WG, Swedberg K, Tyl B, Zannad F, Boulton C, De Graeff P. New medicinal products for chronic heart failure: advances in clinical trial design and efficacy assessment. Eur J Heart Fail. 2017 06; 19(6):718-727. PMID: 28345190.
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  58. Biering-Sørensen T, Shah SJ, Anand I, Sweitzer N, Claggett B, Liu L, Pitt B, Pfeffer MA, Solomon SD, Shah AM. Prognostic importance of left ventricular mechanical dyssynchrony in heart failure with preserved ejection fraction. Eur J Heart Fail. 2017 08; 19(8):1043-1052. PMID: 28322009.
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  59. Abdul-Rahim AH, Perez AC, MacIsaac RL, Jhund PS, Claggett BL, Carson PE, Komajda M, McKelvie RS, Zile MR, Swedberg K, Yusuf S, Pfeffer MA, Solomon SD, Lip GYH, Lees KR, McMurray JJV. Risk of stroke in chronic heart failure patients with preserved ejection fraction, but without atrial fibrillation: analysis of the CHARM-Preserved and I-Preserve trials. Eur Heart J. 2017 Mar 07; 38(10):742-750. PMID: 28426886.
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  60. Fleming TR, DeMets DL, Roe MT, Wittes J, Calis KA, Vora AN, Meisel A, Bain RP, Konstam MA, Pencina MJ, Gordon DJ, Mahaffey KW, Hennekens CH, Neaton JD, Pearson GD, Andersson TL, Pfeffer MA, Ellenberg SS. Data monitoring committees: Promoting best practices to address emerging challenges. Clin Trials. 2017 Apr; 14(2):115-123. PMID: 28359194.
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  61. Fleming TR, DeMets DL, Roe MT, Wittes J, Calis KA, Vora AN, Meisel A, Bain RP, Konstam MA, Pencina MJ, Gordon DJ, Mahaffey KW, Hennekens CH, Neaton JD, Pearson GD, Andersson TL, Pfeffer MA, Ellenberg SS. Rejoinder. Clin Trials. 2017 04; 14(2):126-127. PMID: 28135837.
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  62. Pfeffer MA, McMurray JJ. Clinical Trials Involving Hypertension. N Engl J Med. 2017 01 19; 376(3):290. PMID: 28099831.
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  63. Hennekens CH, Teng B, Pfeffer MA. Statins and Diabetes: Current Perspectives and Implications for Clinicians. Am J Med. 2017 May; 130(5):504-506. PMID: 28089803.
    View in: PubMed
  64. Jarolim P, Claggett BL, Conrad MJ, Carpenter MA, Ivanova A, Bostom AG, Kusek JW, Hunsicker LG, Jacques PF, Gravens-Mueller L, Finn P, Solomon SD, Weiner DE, Levey AS, Pfeffer MA. B-Type Natriuretic Peptide and Cardiac Troponin I Are Associated With Adverse Outcomes in Stable Kidney Transplant Recipients. Transplantation. 2017 Jan; 101(1):182-190. PMID: 26910333.
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  151. Eickmeier O, Seki H, Haworth O, Hilberath JN, Gao F, Uddin M, Croze RH, Carlo T, Pfeffer MA, Levy BD. Aspirin-triggered resolvin D1 reduces mucosal inflammation and promotes resolution in a murine model of acute lung injury. Mucosal Immunol. 2013 Mar; 6(2):256-66. PMID: 22785226; PMCID: PMC3511650.
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  155. Parving HH, Brenner BM, McMurray JJ, de Zeeuw D, Haffner SM, Solomon SD, Chaturvedi N, Persson F, Nicolaides M, Richard A, Xiang Z, Armbrecht J, Pfeffer MA. Baseline characteristics in the Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE). J Renin Angiotensin Aldosterone Syst. 2012 Sep; 13(3):387-93. PMID: 22333485.
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  156. Meris A, Amigoni M, Verma A, Thune JJ, Køber L, Velazquez E, McMurray JJ, Pfeffer MA, Califf R, Levine RA, Solomon SD. Mechanisms and predictors of mitral regurgitation after high-risk myocardial infarction. J Am Soc Echocardiogr. 2012 May; 25(5):535-42. PMID: 22305962; PMCID: PMC3501447.
  157. Sabatine MS, Morrow DA, de Lemos JA, Omland T, Sloan S, Jarolim P, Solomon SD, Pfeffer MA, Braunwald E. Evaluation of multiple biomarkers of cardiovascular stress for risk prediction and guiding medical therapy in patients with stable coronary disease. Circulation. 2012 Jan 17; 125(2):233-40. PMID: 22179538; PMCID: PMC3277287.
  158. Skali H, Parving HH, Parfrey PS, Burdmann EA, Lewis EF, Ivanovich P, Keithi-Reddy SR, McGill JB, McMurray JJ, Singh AK, Solomon SD, Uno H, Pfeffer MA. Stroke in patients with type 2 diabetes mellitus, chronic kidney disease, and anemia treated with Darbepoetin Alfa: the trial to reduce cardiovascular events with Aranesp therapy (TREAT) experience. Circulation. 2011 Dec 20; 124(25):2903-8. PMID: 22104547.
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  159. Desai AS, Lewis EF, Li R, Solomon SD, Assmann SF, Boineau R, Clausell N, Diaz R, Fleg JL, Gordeev I, McKinlay S, O'Meara E, Shaburishvili T, Pitt B, Pfeffer MA. Rationale and design of the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial: a randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction. Am Heart J. 2011 Dec; 162(6):966-972.e10. PMID: 22137068.
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  160. Ariti CA, Cleland JG, Pocock SJ, Pfeffer MA, Swedberg K, Granger CB, McMurray JJ, Michelson EL, Ostergren J, Yusuf S. Days alive and out of hospital and the patient journey in patients with heart failure: Insights from the candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) program. Am Heart J. 2011 Nov; 162(5):900-6. PMID: 22093207.
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  162. Shah AM, Shin SH, Takeuchi M, Skali H, Desai AS, Køber L, Maggioni AP, Rouleau JL, Kelly RY, Hester A, Keefe D, McMurray JJ, Pfeffer MA, Solomon SD. Left ventricular systolic and diastolic function, remodelling, and clinical outcomes among patients with diabetes following myocardial infarction and the influence of direct renin inhibition with aliskiren. Eur J Heart Fail. 2012 Feb; 14(2):185-92. PMID: 21965526.
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  173. Bostom AG, Carpenter MA, Kusek JW, Levey AS, Hunsicker L, Pfeffer MA, Selhub J, Jacques PF, Cole E, Gravens-Mueller L, House AA, Kew C, McKenney JL, Pacheco-Silva A, Pesavento T, Pirsch J, Smith S, Solomon S, Weir M. Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial. Circulation. 2011 Apr 26; 123(16):1763-70. PMID: 21482964; PMCID: PMC4887854.
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  177. Lewis EF, Pfeffer MA, Feng A, Uno H, McMurray JJ, Toto R, Gandra SR, Solomon SD, Moustafa M, Macdougall IC, Locatelli F, Parfrey PS. Darbepoetin alfa impact on health status in diabetes patients with kidney disease: a randomized trial. Clin J Am Soc Nephrol. 2011 Apr; 6(4):845-55. PMID: 21212421; PMCID: PMC3069378.
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  201. Piccini JP, Zhang M, Pieper K, Solomon SD, Al-Khatib SM, Van de Werf F, Pfeffer MA, McMurray JJ, Califf RM, Velazquez EJ. Predictors of sudden cardiac death change with time after myocardial infarction: results from the VALIANT trial. Eur Heart J. 2010 Jan; 31(2):211-21. PMID: 19854729.
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  202. Tonelli M, Curhan G, Pfeffer M, Sacks F, Thadhani R, Melamed ML, Wiebe N, Muntner P. Relation between alkaline phosphatase, serum phosphate, and all-cause or cardiovascular mortality. Circulation. 2009 Nov 03; 120(18):1784-92. PMID: 19841303.
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  205. Jackson CE, Solomon SD, Gerstein HC, Zetterstrand S, Olofsson B, Michelson EL, Granger CB, Swedberg K, Pfeffer MA, Yusuf S, McMurray JJ. Albuminuria in chronic heart failure: prevalence and prognostic importance. Lancet. 2009 Aug 15; 374(9689):543-50. PMID: 19683640.
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  207. Parving HH, Brenner BM, McMurray JJ, de Zeeuw D, Haffner SM, Solomon SD, Chaturvedi N, Pfeffer MA. Dual renin-angiotensin system blockade and kidney disease. J Am Coll Cardiol. 2009 Jul 14; 54(3):278-9; author reply 279-80. PMID: 19589445.
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  209. Moukarbel GV, Signorovitch JE, Pfeffer MA, McMurray JJ, White HD, Maggioni AP, Velazquez EJ, Califf RM, Scheiman JM, Solomon SD. Gastrointestinal bleeding in high risk survivors of myocardial infarction: the VALIANT Trial. Eur Heart J. 2009 Sep; 30(18):2226-32. PMID: 19556260.
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  210. Pfeffer MA, Burdmann EA, Chen CY, Cooper ME, de Zeeuw D, Eckardt KU, Ivanovich P, Kewalramani R, Levey AS, Lewis EF, McGill J, McMurray JJ, Parfrey P, Parving HH, Remuzzi G, Singh AK, Solomon SD, Toto R, Uno H. Baseline characteristics in the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT). Am J Kidney Dis. 2009 Jul; 54(1):59-69. PMID: 19501439.
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  211. Califf RM, Lokhnygina Y, Velazquez EJ, McMurray JJ, Leimberger JD, Lewis EF, Diaz R, Murin J, Pfeffer MA. Usefulness of beta blockers in high-risk patients after myocardial infarction in conjunction with captopril and/or valsartan (from the VALsartan In Acute Myocardial Infarction [VALIANT] trial). Am J Cardiol. 2009 Jul 15; 104(2):151-7. PMID: 19576338.
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  217. Preiss D, Zetterstrand S, McMurray JJ, Ostergren J, Michelson EL, Granger CB, Yusuf S, Swedberg K, Pfeffer MA, Gerstein HC, Sattar N. Predictors of development of diabetes in patients with chronic heart failure in the Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM) program. Diabetes Care. 2009 May; 32(5):915-20. PMID: 19196892; PMCID: PMC2671104.
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  219. Hawkins NM, Huang Z, Pieper KS, Solomon SD, Kober L, Velazquez EJ, Swedberg K, Pfeffer MA, McMurray JJ, Maggioni AP. Chronic obstructive pulmonary disease is an independent predictor of death but not atherosclerotic events in patients with myocardial infarction: analysis of the Valsartan in Acute Myocardial Infarction Trial (VALIANT). Eur J Heart Fail. 2009 Mar; 11(3):292-8. PMID: 19176539; PMCID: PMC2645058.
  220. Parving HH, Brenner BM, McMurray JJ, de Zeeuw D, Haffner SM, Solomon SD, Chaturvedi N, Ghadanfar M, Weissbach N, Xiang Z, Armbrecht J, Pfeffer MA. Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE): rationale and study design. Nephrol Dial Transplant. 2009 May; 24(5):1663-71. PMID: 19145003.
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  223. Bostom AG, Carpenter MA, Hunsicker L, Jacques PF, Kusek JW, Levey AS, McKenney JL, Mercier RY, Pfeffer MA, Selhub J. Baseline characteristics of participants in the Folic Acid for Vascular Outcome Reduction in Transplantation (FAVORIT) Trial. Am J Kidney Dis. 2009 Jan; 53(1):121-8. PMID: 19022547; PMCID: PMC2682551.
  224. Meris A, Amigoni M, Uno H, Thune JJ, Verma A, Køber L, Bourgoun M, McMurray JJ, Velazquez EJ, Maggioni AP, Ghali J, Arnold JM, Zelenkofske S, Pfeffer MA, Solomon SD. Left atrial remodelling in patients with myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: the VALIANT Echo study. Eur Heart J. 2009 Jan; 30(1):56-65. PMID: 19001474.
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  225. Abrahamsson P, Dobson J, Granger CB, McMurray JJ, Michelson EL, Pfeffer M, Pocock S, Solomon SD, Yusuf S, Swedberg K. Impact of hospitalization for acute coronary events on subsequent mortality in patients with chronic heart failure. Eur Heart J. 2009 Feb; 30(3):338-45. PMID: 19001475.
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  226. Cohen-Solal A, McMurray JJ, Swedberg K, Pfeffer MA, Puu M, Solomon SD, Michelson EL, Yusuf S, Granger CB. Benefits and safety of candesartan treatment in heart failure are independent of age: insights from the Candesartan in Heart failure--Assessment of Reduction in Mortality and morbidity programme. Eur Heart J. 2008 Dec; 29(24):3022-8. PMID: 18987098.
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  227. Tian L, Cai T, Pfeffer MA, Piankov N, Cremieux PY, Wei LJ. Exact and efficient inference procedure for meta-analysis and its application to the analysis of independent 2 x 2 tables with all available data but without artificial continuity correction. Biostatistics. 2009 Apr; 10(2):275-81. PMID: 18922759; PMCID: PMC2648899.
  228. Pocock SJ, McMurray JJ, Dobson J, Yusuf S, Granger CB, Michelson EL, Ostergren J, Pfeffer MA, Solomon SD, Anker SD, Swedberg KB. Weight loss and mortality risk in patients with chronic heart failure in the candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) programme. Eur Heart J. 2008 Nov; 29(21):2641-50. PMID: 18819960.
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  229. Verma A, Meris A, Skali H, Ghali JK, Arnold JM, Bourgoun M, Velazquez EJ, McMurray JJ, Kober L, Pfeffer MA, Califf RM, Solomon SD. Prognostic implications of left ventricular mass and geometry following myocardial infarction: the VALIANT (VALsartan In Acute myocardial iNfarcTion) Echocardiographic Study. JACC Cardiovasc Imaging. 2008 Sep; 1(5):582-91. PMID: 19356485.
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  230. Gerstein HC, Swedberg K, Carlsson J, McMurray JJ, Michelson EL, Olofsson B, Pfeffer MA, Yusuf S. The hemoglobin A1c level as a progressive risk factor for cardiovascular death, hospitalization for heart failure, or death in patients with chronic heart failure: an analysis of the Candesartan in Heart failure: Assessment of Reduction in Mortality and Morbidity (CHARM) program. Arch Intern Med. 2008 Aug 11; 168(15):1699-704. PMID: 18695086.
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  231. Tardif JC, McMurray JJ, Klug E, Small R, Schumi J, Choi J, Cooper J, Scott R, Lewis EF, L'Allier PL, Pfeffer MA. Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial. Lancet. 2008 May 24; 371(9626):1761-8. PMID: 18502300.
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  232. Prisant LM, Thomas KL, Lewis EF, Huang Z, Francis GS, Weaver WD, Pfeffer MA, McMurray JJ, Califf RM, Velazquez EJ. Racial analysis of patients with myocardial infarction complicated by heart failure and/or left ventricular dysfunction treated with valsartan, captopril, or both. J Am Coll Cardiol. 2008 May 13; 51(19):1865-71. PMID: 18466801.
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  233. MacDonald MR, Petrie MC, Varyani F, Ostergren J, Michelson EL, Young JB, Solomon SD, Granger CB, Swedberg K, Yusuf S, Pfeffer MA, McMurray JJ. Impact of diabetes on outcomes in patients with low and preserved ejection fraction heart failure: an analysis of the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) programme. Eur Heart J. 2008 Jun; 29(11):1377-85. PMID: 18413309.
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  234. Pfeffer MA. Anemia treatment in chronic kidney disease: shifting uncertainty. Heart Fail Rev. 2008 Dec; 13(4):425-30. PMID: 18401704.
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  235. Anavekar NS, Solomon SD, McMurray JJ, Maggioni A, Rouleau JL, Califf R, White H, Kober L, Velazquez E, Pfeffer MA. Comparison of renal function and cardiovascular risk following acute myocardial infarction in patients with and without diabetes mellitus. Am J Cardiol. 2008 Apr 01; 101(7):925-9. PMID: 18359309.
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  236. Healey JS, Hart RG, Pogue J, Pfeffer MA, Hohnloser SH, De Caterina R, Flaker G, Yusuf S, Connolly SJ. Risks and benefits of oral anticoagulation compared with clopidogrel plus aspirin in patients with atrial fibrillation according to stroke risk: the atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events (ACTIVE-W). Stroke. 2008 May; 39(5):1482-6. PMID: 18323500.
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  237. Anavekar NS, Skali H, Bourgoun M, Ghali JK, Kober L, Maggioni AP, McMurray JJ, Velazquez E, Califf R, Pfeffer MA, Solomon SD. Usefulness of right ventricular fractional area change to predict death, heart failure, and stroke following myocardial infarction (from the VALIANT ECHO Study). Am J Cardiol. 2008 Mar 01; 101(5):607-12. PMID: 18308007.
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  238. Pfeffer MA. Critical missing data on erythropoiesis-stimulating agents in CKD: first beat placebo. Am J Kidney Dis. 2008 Mar; 51(3):366-9. PMID: 18295051.
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  239. Lewis EF, Velazquez EJ, Solomon SD, Hellkamp AS, McMurray JJ, Mathias J, Rouleau JL, Maggioni AP, Swedberg K, Kober L, White H, Dalby AJ, Francis GS, Zannad F, Califf RM, Pfeffer MA. Predictors of the first heart failure hospitalization in patients who are stable survivors of myocardial infarction complicated by pulmonary congestion and/or left ventricular dysfunction: a VALIANT study. Eur Heart J. 2008 Mar; 29(6):748-56. PMID: 18308687.
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  240. Mielniczuk LM, Pfeffer MA, Lewis EF, Blazing MA, de Lemos JA, Shui A, Mohanavelu S, Califf RM, Braunwald E. Estimated glomerular filtration rate, inflammation, and cardiovascular events after an acute coronary syndrome. Am Heart J. 2008 Apr; 155(4):725-31. PMID: 18371483.
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  242. Weir RA, McMurray JJ, Puu M, Solomon SD, Olofsson B, Granger CB, Yusuf S, Michelson EL, Swedberg K, Pfeffer MA. Efficacy and tolerability of adding an angiotensin receptor blocker in patients with heart failure already receiving an angiotensin-converting inhibitor plus aldosterone antagonist, with or without a beta blocker. Findings from the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM)-Added trial. Eur J Heart Fail. 2008 Feb; 10(2):157-63. PMID: 18242128.
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  243. Iakoubova OA, Tong CH, Rowland CM, Kirchgessner TG, Young BA, Arellano AR, Shiffman D, Sabatine MS, Campos H, Packard CJ, Pfeffer MA, White TJ, Braunwald E, Shepherd J, Devlin JJ, Sacks FM. Association of the Trp719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials. J Am Coll Cardiol. 2008 Jan 29; 51(4):435-43. PMID: 18222353.
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  244. Sabatine MS, Ploughman L, Simonsen KL, Iakoubova OA, Kirchgessner TG, Ranade K, Tsuchihashi Z, Zerba KE, Long DU, Tong CH, Packard CJ, Pfeffer MA, Devlin JJ, Shepherd J, Campos H, Sacks FM, Braunwald E. Association between ADAMTS1 matrix metalloproteinase gene variation, coronary heart disease, and benefit of statin therapy. Arterioscler Thromb Vasc Biol. 2008 Mar; 28(3):562-7. PMID: 18174457.
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  245. Tonelli M, Sacks F, Arnold M, Moye L, Davis B, Pfeffer M. Relation Between Red Blood Cell Distribution Width and Cardiovascular Event Rate in People With Coronary Disease. Circulation. 2008 Jan 15; 117(2):163-168. PMID: 18172029.
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  246. Mitchell GF, Conlin PR, Dunlap ME, Lacourcière Y, Arnold JM, Ogilvie RI, Neutel J, Izzo JL, Pfeffer MA. Aortic diameter, wall stiffness, and wave reflection in systolic hypertension. Hypertension. 2008 Jan; 51(1):105-11. PMID: 18071054.
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  247. Solomon SD, Lin J, Solomon CG, Jablonski KA, Rice MM, Steffes M, Domanski M, Hsia J, Gersh BJ, Arnold JM, Rouleau J, Braunwald E, Pfeffer MA. Influence of albuminuria on cardiovascular risk in patients with stable coronary artery disease. Circulation. 2007 Dec 04; 116(23):2687-93. PMID: 18025537.
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  249. Hohnloser SH, Pajitnev D, Pogue J, Healey JS, Pfeffer MA, Yusuf S, Connolly SJ. Incidence of stroke in paroxysmal versus sustained atrial fibrillation in patients taking oral anticoagulation or combined antiplatelet therapy: an ACTIVE W Substudy. J Am Coll Cardiol. 2007 Nov 27; 50(22):2156-61. PMID: 18036454.
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  254. Borer JS, Pouleur H, Abadie E, Follath F, Wittes J, Pfeffer MA, Pitt B, Zannad F. Cardiovascular safety of drugs not intended for cardiovascular use: need for a new conceptual basis for assessment and approval. Eur Heart J. 2007 Aug; 28(15):1904-9. PMID: 17615083.
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  273. Wölfel R, Terzioglu R, Kiessling J, Wilhelm S, Essbauer S, Pfeffer M, Dobler G. Rickettsia spp. in Ixodes ricinus ticks in Bavaria, Germany. Ann N Y Acad Sci. 2006 Oct; 1078:509-11. PMID: 17114766.
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  279. Aguilar D, Fisher MR, O'Connor CM, Dunne MW, Muhlestein JB, Yao L, Gupta S, Benner RJ, Cook TD, Edwards D, Pfeffer MA. Metabolic syndrome, C-reactive protein, and prognosis in patients with established coronary artery disease. Am Heart J. 2006 Aug; 152(2):298-304. PMID: 16875914.
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  361. Pfeffer MA. Pharmacologic advances in long-term heart failure management. Am Heart Hosp J. 2004; 2(4 Suppl 1):15-20. PMID: 15539971.
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  362. Kenchaiah S, Pfeffer MA. Cardiac remodeling in systemic hypertension. Med Clin North Am. 2004 Jan; 88(1):115-30. PMID: 14871054.
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  363. Pfeffer M. [New options against undertreatment]. MMW Fortschr Med. 2003 Dec 04; 145(49):18. PMID: 14963987.
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  364. Pfeffer MA, McMurray JJ, Velazquez EJ, Rouleau JL, Køber L, Maggioni AP, Solomon SD, Swedberg K, Van de Werf F, White H, Leimberger JD, Henis M, Edwards S, Zelenkofske S, Sellers MA, Califf RM. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med. 2003 Nov 13; 349(20):1893-906. PMID: 14610160.
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  365. Solomon SD, Pfeffer MA. Aldosterone antagonism and myocardial infarction: from animals to man and back. J Am Coll Cardiol. 2003 Nov 05; 42(9):1674-6. PMID: 14607458.
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  366. Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, McCullough PA, Kasiske BL, Kelepouris E, Klag MJ, Parfrey P, Pfeffer M, Raij L, Spinosa DJ, Wilson PW. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Hypertension. 2003 Nov; 42(5):1050-65. PMID: 14604997.
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  367. Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, McCullough PA, Kasiske BL, Kelepouris E, Klag MJ, Parfrey P, Pfeffer M, Raij L, Spinosa DJ, Wilson PW. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation. 2003 Oct 28; 108(17):2154-69. PMID: 14581387.
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  368. Lewis EF, Moye LA, Rouleau JL, Sacks FM, Arnold JM, Warnica JW, Flaker GC, Braunwald E, Pfeffer MA. Predictors of late development of heart failure in stable survivors of myocardial infarction: the CARE study. J Am Coll Cardiol. 2003 Oct 15; 42(8):1446-53. PMID: 14563590.
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  369. Cohn JN, Pfeffer MA, Rouleau J, Sharpe N, Swedberg K, Straub M, Wiltse C, Wright TJ. Adverse mortality effect of central sympathetic inhibition with sustained-release moxonidine in patients with heart failure (MOXCON). Eur J Heart Fail. 2003 Oct; 5(5):659-67. PMID: 14607206.
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  370. O'Connor CM, Dunne MW, Pfeffer MA, Muhlestein JB, Yao L, Gupta S, Benner RJ, Fisher MR, Cook TD. Azithromycin for the secondary prevention of coronary heart disease events: the WIZARD study: a randomized controlled trial. JAMA. 2003 Sep 17; 290(11):1459-66. PMID: 13129985.
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  371. Mitchell GF, Lacourcière Y, Ouellet JP, Izzo JL, Neutel J, Kerwin LJ, Block AJ, Pfeffer MA. Determinants of elevated pulse pressure in middle-aged and older subjects with uncomplicated systolic hypertension: the role of proximal aortic diameter and the aortic pressure-flow relationship. Circulation. 2003 Sep 30; 108(13):1592-8. PMID: 12975261.
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  372. Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ, Michelson EL, Olofsson B, Ostergren J. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet. 2003 Sep 06; 362(9386):777-81. PMID: 13678871.
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  373. McMurray JJ, Ostergren J, Swedberg K, Granger CB, Held P, Michelson EL, Olofsson B, Yusuf S, Pfeffer MA. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet. 2003 Sep 06; 362(9386):767-71. PMID: 13678869.
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  374. Granger CB, McMurray JJ, Yusuf S, Held P, Michelson EL, Olofsson B, Ostergren J, Pfeffer MA, Swedberg K. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial. Lancet. 2003 Sep 06; 362(9386):772-6. PMID: 13678870.
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  375. Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ, Michelson EL, Olofsson B, Ostergren J, Yusuf S, Pocock S. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet. 2003 Sep 06; 362(9386):759-66. PMID: 13678868.
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  376. Velazquez EJ, Pfeffer MA, McMurray JV, Maggioni AP, Rouleau JL, Van de Werf F, Kober L, White HD, Swedberg K, Leimberger JD, Gallo P, Sellers MA, Edwards S, Henis M, Califf RM. VALsartan In Acute myocardial iNfarcTion (VALIANT) trial: baseline characteristics in context. Eur J Heart Fail. 2003 Aug; 5(4):537-44. PMID: 12921816.
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  377. Pfeffer MA. Cardiac function and heart failure. J Am Coll Cardiol. 2003 Jul 16; 42(2):390-2. PMID: 12875786.
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  378. McMurray J, Ostergren J, Pfeffer M, Swedberg K, Granger C, Yusuf S, Held P, Michelson E, Olofsson B. Clinical features and contemporary management of patients with low and preserved ejection fraction heart failure: baseline characteristics of patients in the Candesartan in Heart failure-Assessment of Reduction in Mortality and morbidity (CHARM) programme. Eur J Heart Fail. 2003 Jun; 5(3):261-70. PMID: 12798823.
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  379. St John Sutton M, Lee D, Rouleau JL, Goldman S, Plappert T, Braunwald E, Pfeffer MA. Left ventricular remodeling and ventricular arrhythmias after myocardial infarction. Circulation. 2003 May 27; 107(20):2577-82. PMID: 12732606.
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  380. Berl T, Hunsicker LG, Lewis JB, Pfeffer MA, Porush JG, Rouleau JL, Drury PL, Esmatjes E, Hricik D, Parikh CR, Raz I, Vanhille P, Wiegmann TB, Wolfe BM, Locatelli F, Goldhaber SZ, Lewis EJ. Cardiovascular outcomes in the Irbesartan Diabetic Nephropathy Trial of patients with type 2 diabetes and overt nephropathy. Ann Intern Med. 2003 Apr 01; 138(7):542-9. PMID: 12667024.
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  381. Jilaihawi H, Greaves S, Rouleau JL, Pfeffer MA, Solomon SD. Left ventricular hypertrophy and the risk of subsequent left ventricular remodeling following myocardial infarction. Am J Cardiol. 2003 Mar 15; 91(6):723-6. PMID: 12633808.
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  382. Manes C, Pfeffer MA, Rutherford JD, Greaves S, Rouleau JL, Arnold JM, Menapace F, Solomon SD. Value of the electrocardiogram in predicting left ventricular enlargement and dysfunction after myocardial infarction. Am J Med. 2003 Feb 01; 114(2):99-105. PMID: 12586228.
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  383. Fleming T, Borer J, Armstrong PW, Pfeffer M. Food and Drug Administration: Cardiovascular and Renal Drugs Advisory Committee, 98th meeting, January 6th-7th, 2003. Circulation. 2003 Jan 21; 107(2):e9002-3. PMID: 12538443.
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  384. Pfeffer MA. Janice M. Pfeffer Memorial Lecture. J Card Fail. 2002 Dec; 8(6 Suppl):S248-52. PMID: 12555127.
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  385. Solomon SD, Pfeffer MA. Renin-angiotensin system and cardiac rupture after myocardial infarction. Circulation. 2002 Oct 22; 106(17):2167-9. PMID: 12390941.
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  386. Teo KK, Yusuf S, Pfeffer M, Torp-Pedersen C, Kober L, Hall A, Pogue J, Latini R, Collins R. Effects of long-term treatment with angiotensin-converting-enzyme inhibitors in the presence or absence of aspirin: a systematic review. Lancet. 2002 Oct 05; 360(9339):1037-43. PMID: 12383982.
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  387. Solomon SD, St John Sutton M, Lamas GA, Plappert T, Rouleau JL, Skali H, Moyé L, Braunwald E, Pfeffer MA. Ventricular remodeling does not accompany the development of heart failure in diabetic patients after myocardial infarction. Circulation. 2002 Sep 03; 106(10):1251-5. PMID: 12208801.
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  388. Pfeffer M. Myocardial infarction and heart failure-a dangerous intersection. Am J Med. 2002 Sep; 113(4):341-3. PMID: 12361824.
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  389. Mitchell GF, Izzo JL, Lacourcière Y, Ouellet JP, Neutel J, Qian C, Kerwin LJ, Block AJ, Pfeffer MA. Omapatrilat reduces pulse pressure and proximal aortic stiffness in patients with systolic hypertension: results of the conduit hemodynamics of omapatrilat international research study. Circulation. 2002 Jun 25; 105(25):2955-61. PMID: 12081987.
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  390. Pfeffer MA, McMurray JJ. Myocardial infarct: no one size fits all. Circulation. 2002 Jun 04; 105(22):2577-9. PMID: 12045157.
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  391. Pfeffer MA, Keech A, Sacks FM, Cobbe SM, Tonkin A, Byington RP, Davis BR, Friedman CP, Braunwald E. Safety and tolerability of pravastatin in long-term clinical trials: prospective Pravastatin Pooling (PPP) Project. Circulation. 2002 May 21; 105(20):2341-6. PMID: 12021218.
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  392. Johnson W, Omland T, Hall C, Lucas C, Myking OL, Collins C, Pfeffer M, Rouleau JL, Stevenson LW. Neurohormonal activation rapidly decreases after intravenous therapy with diuretics and vasodilators for class IV heart failure. J Am Coll Cardiol. 2002 May 15; 39(10):1623-9. PMID: 12020489.
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  393. McMurray J, Pfeffer MA. New therapeutic options in congestive heart failure: Part II. Circulation. 2002 May 07; 105(18):2223-8. PMID: 11994259.
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  394. Zornoff LA, Skali H, Pfeffer MA, St John Sutton M, Rouleau JL, Lamas GA, Plappert T, Rouleau JR, Moyé LA, Lewis SJ, Braunwald E, Solomon SD. Right ventricular dysfunction and risk of heart failure and mortality after myocardial infarction. J Am Coll Cardiol. 2002 May 01; 39(9):1450-5. PMID: 11985906.
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  395. Domanski M, Mitchell G, Pfeffer M, Neaton JD, Norman J, Svendsen K, Grimm R, Cohen J, Stamler J. Pulse pressure and cardiovascular disease-related mortality: follow-up study of the Multiple Risk Factor Intervention Trial (MRFIT). JAMA. 2002 May 22-29; 287(20):2677-83. PMID: 12020303.
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  396. McMurray J, Pfeffer MA. New therapeutic options in congestive heart failure: Part I. Circulation. 2002 Apr 30; 105(17):2099-106. PMID: 11980691.
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  397. Hebert PR, Pfeffer MA, Hennekens CH. Use of statins and aspirin to reduce risks of cardiovascular disease. J Cardiovasc Pharmacol Ther. 2002 Apr; 7(2):77-80. PMID: 12075395.
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  398. Sacks FM, Tonkin AM, Craven T, Pfeffer MA, Shepherd J, Keech A, Furberg CD, Braunwald E. Coronary heart disease in patients with low LDL-cholesterol: benefit of pravastatin in diabetics and enhanced role for HDL-cholesterol and triglycerides as risk factors. Circulation. 2002 Mar 26; 105(12):1424-8. PMID: 11914249.
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  399. Skali H, Solomon SD, Pfeffer MA. Are we asking too much of our trials? Am Heart J. 2002 Jan; 143(1):1-3. PMID: 11773904.
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  400. Zee RY, Solomon SD, Ajani UA, Pfeffer MA, Lindpaintner K. A prospective evaluation of the angiotensin-converting enzyme D/I polymorphism and left ventricular remodeling in the 'Healing and Early Afterload Reducing Therapy' study. Clin Genet. 2002 Jan; 61(1):21-5. PMID: 11903350.
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  401. Mitchell GF, Tardif JC, Arnold JM, Marchiori G, O'Brien TX, Dunlap ME, Pfeffer MA. Pulsatile hemodynamics in congestive heart failure. Hypertension. 2001 Dec 01; 38(6):1433-9. PMID: 11751731.
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  402. White M, Rouleau JL, Hall C, Arnold M, Harel F, Sirois P, Greaves S, Solomon S, Ajani U, Glynn R, Hennekens C, Pfeffer M. Changes in vasoconstrictive hormones, natriuretic peptides, and left ventricular remodeling soon after anterior myocardial infarction. Am Heart J. 2001 Dec; 142(6):1056-64. PMID: 11717612.
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  403. Skali H, Pfeffer MA. Prospects for ARB in the next five years. J Renin Angiotensin Aldosterone Syst. 2001 Dec; 2(4):215-8. PMID: 11881126.
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  404. Smith SC, Blair SN, Bonow RO, Brass LM, Cerqueira MD, Dracup K, Fuster V, Gotto A, Grundy SM, Miller NH, Jacobs A, Jones D, Krauss RM, Mosca L, Ockene I, Pasternak RC, Pearson T, Pfeffer MA, Starke RD, Taubert KA. AHA/ACC Guidelines for Preventing Heart Attack and Death in Patients With Atherosclerotic Cardiovascular Disease: 2001 update. A statement for healthcare professionals from the American Heart Association and the American College of Cardiology. J Am Coll Cardiol. 2001 Nov 01; 38(5):1581-3. PMID: 11691544.
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  405. Domanski M, Norman J, Wolz M, Mitchell G, Pfeffer M. Cardiovascular risk assessment using pulse pressure in the first national health and nutrition examination survey (NHANES I). Hypertension. 2001 Oct; 38(4):793-7. PMID: 11641288.
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  406. Smith SC, Blair SN, Bonow RO, Brass LM, Cerqueira MD, Dracup K, Fuster V, Gotto A, Grundy SM, Miller NH, Jacobs A, Jones D, Krauss RM, Mosca L, Ockene I, Pasternak RC, Pearson T, Pfeffer MA, Starke RD, Taubert KA. AHA/ACC Scientific Statement: AHA/ACC guidelines for preventing heart attack and death in patients with atherosclerotic cardiovascular disease: 2001 update: A statement for healthcare professionals from the American Heart Association and the American College of Cardiology. Circulation. 2001 Sep 25; 104(13):1577-9. PMID: 11571256.
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  407. Ritleng V, Bertani P, Pfeffer M, Sirlin C, Hirschinger J. Optically active ortho-metalated half-sandwich ruthenium complexes: solid-state NMR as a convenient tool to analyze mixtures of diastereomers. Inorg Chem. 2001 Sep 24; 40(20):5117-22. PMID: 11559068.
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  408. Pfeffer MA, Domanski M, Verter J, Dunlap M, Flaker GC, Gersh B, Hsia J, Goldberg AD, Limacher MC, Maggioni AP, Rosenberg Y, Rouleau JL, Warnica JW, Wasserman AG, Braunwald E. The continuation of the Prevention of Events With Angiotensin-Converting Enzyme Inhibition (PEACE) Trial. Am Heart J. 2001 Sep; 142(3):375-7. PMID: 11526345.
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  409. Bray PF, Cannon CP, Goldschmidt-Clermont P, Moyé LA, Pfeffer MA, Sacks FM, Braunwald E. The platelet Pl(A2) and angiotensin-converting enzyme (ACE) D allele polymorphisms and the risk of recurrent events after acute myocardial infarction. Am J Cardiol. 2001 Aug 15; 88(4):347-52. PMID: 11545752.
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  410. Fischer TA, Ludwig S, Flory E, Gambaryan S, Singh K, Finn P, Pfeffer MA, Kelly RA, Pfeffer JM. Activation of cardiac c-Jun NH(2)-terminal kinases and p38-mitogen-activated protein kinases with abrupt changes in hemodynamic load. Hypertension. 2001 May; 37(5):1222-8. PMID: 11358932.
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  411. Solomon SD, Glynn RJ, Greaves S, Ajani U, Rouleau JL, Menapace F, Arnold JM, Hennekens C, Pfeffer MA. Recovery of ventricular function after myocardial infarction in the reperfusion era: the healing and early afterload reducing therapy study. Ann Intern Med. 2001 Mar 20; 134(6):451-8. PMID: 11255520.
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  412. Aikawa Y, Rohde L, Plehn J, Greaves SC, Menapace F, Arnold MO, Rouleau JL, Pfeffer MA, Lee RT, Solomon SD. Regional wall stress predicts ventricular remodeling after anteroseptal myocardial infarction in the Healing and Early Afterload Reducing Trial (HEART): an echocardiography-based structural analysis. Am Heart J. 2001 Feb; 141(2):234-42. PMID: 11174337.
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  413. Pfeffer MA. New treasures from old? EPHESUS. Eplerenome Post-AHI Heart Failure Efficacy and Survival Study. Cardiovasc Drugs Ther. 2001 Jan; 15(1):11-3. PMID: 11504157.
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  414. Pfeffer MA. Statins: a brief summary. Clin Cardiol. 2001; 24(7 Suppl):II-18. PMID: 11444650.
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  415. Pfeffer JM, Finn PV, Zornoff LA, Pfeffer MA. Endothelin-A receptor antagonism during acute myocardial infarction in rats. Cardiovasc Drugs Ther. 2000 Dec; 14(6):579-87. PMID: 11300358.
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  416. Pfeffer MA, McMurray J, Leizorovicz A, Maggioni AP, Rouleau JL, Van De Werf F, Henis M, Neuhart E, Gallo P, Edwards S, Sellers MA, Velazquez E, Califf R. Valsartan in acute myocardial infarction trial (VALIANT): rationale and design. Am Heart J. 2000 Nov; 140(5):727-50. PMID: 11054617.
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  417. Sacks FM, Alaupovic P, Moye LA, Cole TG, Sussex B, Stampfer MJ, Pfeffer MA, Braunwald E. VLDL, apolipoproteins B, CIII, and E, and risk of recurrent coronary events in the Cholesterol and Recurrent Events (CARE) trial. Circulation. 2000 Oct 17; 102(16):1886-92. PMID: 11034934.
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  418. Shah MR, Granger CB, Bart BA, McMurray JJ, Petrie MC, Michelson EL, Tudor GE, Swedberg K, Stevenson LW, Califf RM, Pfeffer MA. Sex-related differences in the use and adverse effects of angiotensin-converting enzyme inhibitors in heart failure: the study of patients intolerant of converting enzyme inhibitors registry. Am J Med. 2000 Oct 15; 109(6):489-92. PMID: 11042239.
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  419. Rouleau JL, Pfeffer MA, Stewart DJ, Isaac D, Sestier F, Kerut EK, Porter CB, Proulx G, Qian C, Block AJ. Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial. Lancet. 2000 Aug 19; 356(9230):615-20. PMID: 10968433.
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  420. Lipman NS, Perkins S, Nguyen H, Pfeffer M, Meyer H. Mousepox resulting from use of ectromelia virus-contaminated, imported mouse serum. Comp Med. 2000 Aug; 50(4):426-35. PMID: 11020163.
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  421. Pfeffer MA. Will more complete inhibition of the RAAS with angiotensin receptor blockade improve survival following myocardial infarction? J Renin Angiotensin Aldosterone Syst. 2000 Jun; 1(2 Suppl):S41-3. PMID: 17199221.
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  422. Latini R, Tognoni G, Maggioni AP, Baigent C, Braunwald E, Chen ZM, Collins R, Flather M, Franzosi MG, Kjekshus J, Køber L, Liu LS, Peto R, Pfeffer M, Pizzetti F, Santoro E, Sleight P, Swedberg K, Tavazzi L, Wang W, Yusuf S. Clinical effects of early angiotensin-converting enzyme inhibitor treatment for acute myocardial infarction are similar in the presence and absence of aspirin: systematic overview of individual data from 96,712 randomized patients. Angiotensin-converting Enzyme Inhibitor Myocardial Infarction Collaborative Group. J Am Coll Cardiol. 2000 Jun; 35(7):1801-7. PMID: 10841227.
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  423. Ridker PM, Rifai N, Pfeffer M, Sacks F, Lepage S, Braunwald E. Elevation of tumor necrosis factor-alpha and increased risk of recurrent coronary events after myocardial infarction. Circulation. 2000 May 09; 101(18):2149-53. PMID: 10801754.
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  424. Flather MD, Yusuf S, Køber L, Pfeffer M, Hall A, Murray G, Torp-Pedersen C, Ball S, Pogue J, Moyé L, Braunwald E. Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients. ACE-Inhibitor Myocardial Infarction Collaborative Group. Lancet. 2000 May 06; 355(9215):1575-81. PMID: 10821360.
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  425. Granger CB, Ertl G, Kuch J, Maggioni AP, McMurray J, Rouleau JL, Stevenson LW, Swedberg K, Young J, Yusuf S, Califf RM, Bart BA, Held P, Michelson EL, Sellers MA, Ohlin G, Sparapani R, Pfeffer MA. Randomized trial of candesartan cilexetil in the treatment of patients with congestive heart failure and a history of intolerance to angiotensin-converting enzyme inhibitors. Am Heart J. 2000 Apr; 139(4):609-17. PMID: 10740141.
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  426. Pfeffer MA. Enhancing cardiac protection after myocardial infarction: rationale for newer clinical trials of angiotensin receptor blockers. Am Heart J. 2000 Jan; 139(1 Pt 2):S23-8. PMID: 10618584.
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  427. Amir M, Arish A, Weinstein Y, Pfeffer M, Levy Y. Impairment in quality of life among patients seeking surgery for hyperhidrosis (excessive sweating): preliminary results. Isr J Psychiatry Relat Sci. 2000; 37(1):25-31. PMID: 10857268.
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  428. Swedberg K, Pfeffer M, Granger GB, McMURRAY J, Yusuf S. Candesartan in Heart Failure - Assessment of Reduction in Mortality and Morbidity (CHARM) Study Programme. Blood Press. 2000; 9(sup1):60. PMID: 28425813.
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  429. Meissner JD, Huang CY, Pfeffer M, Kinney RM. Sequencing of prototype viruses in the Venezuelan equine encephalitis antigenic complex. Virus Res. 1999 Oct; 64(1):43-59. PMID: 10500282.
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  430. Levy D, Merz CN, Cody RJ, Fouad-Tarazi FM, Francis CK, Pfeffer MA, Scott NA, Swan HJ, Taylor MP, Weinberger MH. Hypertension detection, treatment and control: a call to action for cardiovascular specialists. J Am Coll Cardiol. 1999 Oct; 34(4):1360-2. PMID: 10520821.
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  431. Domanski MJ, Davis BR, Pfeffer MA, Kastantin M, Mitchell GF. Isolated systolic hypertension : prognostic information provided by pulse pressure. Hypertension. 1999 Sep; 34(3):375-80. PMID: 10489379.
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  432. Grosjean SA, Arstall MA, Mitchell RN, Klappacher GW, Kelly RA, Pfeffer MA, Pfeffer JM. Inducible nitric oxide synthase and tumor necrosis factor in animal models of myocardial necrosis induced by coronary artery ligation or isoproterenol injection. J Card Fail. 1999 Sep; 5(3):236-45. PMID: 10496196.
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  433. Solomon SD, Greaves SC, Rayan M, Finn P, Pfeffer MA, Pfeffer JM. Temporal dissociation of left ventricular function and remodeling following experimental myocardial infarction in rats. J Card Fail. 1999 Sep; 5(3):213-23. PMID: 10496194.
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  434. Swedberg K, Pfeffer M, Granger C, Held P, McMurray J, Ohlin G, Olofsson B, Ostergren J, Yusuf S. Candesartan in heart failure--assessment of reduction in mortality and morbidity (CHARM): rationale and design. Charm-Programme Investigators. J Card Fail. 1999 Sep; 5(3):276-82. PMID: 10496201.
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  435. Mitchell GF, Pfeffer MA. Pulsatile hemodynamics in hypertension. Curr Opin Cardiol. 1999 Sep; 14(5):361-9. PMID: 10500897.
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  436. Bart BA, Ertl G, Held P, Kuch J, Maggioni AP, McMurray J, Michelson EL, Rouleau JL, Warner Stevenson L, Swedberg K, Young JB, Yusuf S, Sellers MA, Granger CB, Califf RM, Pfeffer MA. Contemporary management of patients with left ventricular systolic dysfunction. Results from the Study of Patients Intolerant of Converting Enzyme Inhibitors (SPICE) Registry. Eur Heart J. 1999 Aug; 20(16):1182-90. PMID: 10448027.
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  437. Ridker PM, Rifai N, Pfeffer MA, Sacks F, Braunwald E. Long-term effects of pravastatin on plasma concentration of C-reactive protein. The Cholesterol and Recurrent Events (CARE) Investigators. Circulation. 1999 Jul 20; 100(3):230-5. PMID: 10411845.
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  438. Flaker GC, Warnica JW, Sacks FM, Moyé LA, Davis BR, Rouleau JL, Webel RR, Pfeffer MA, Braunwald E. Pravastatin prevents clinical events in revascularized patients with average cholesterol concentrations. Cholesterol and Recurrent Events CARE Investigators. J Am Coll Cardiol. 1999 Jul; 34(1):106-12. PMID: 10399998.
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  439. Maronde E, Pfeffer M, Olcese J, Molina CA, Schlotter F, Dehghani F, Korf HW, Stehle JH. Transcription factors in neuroendocrine regulation: rhythmic changes in pCREB and ICER levels frame melatonin synthesis. J Neurosci. 1999 May 01; 19(9):3326-36. PMID: 10212292.
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  440. Dunn FG, Pfeffer MA. Left ventricular hypertrophy in hypertension. N Engl J Med. 1999 Apr 22; 340(16):1279-80. PMID: 10210713.
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  441. Domanski MJ, Mitchell GF, Norman JE, Exner DV, Pitt B, Pfeffer MA. Independent prognostic information provided by sphygmomanometrically determined pulse pressure and mean arterial pressure in patients with left ventricular dysfunction. J Am Coll Cardiol. 1999 Mar 15; 33(4):951-8. PMID: 10091821.
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  442. Weaver SC, Pfeffer M, Marriott K, Kang W, Kinney RM. Genetic evidence for the origins of Venezuelan equine encephalitis virus subtype IAB outbreaks. Am J Trop Med Hyg. 1999 Mar; 60(3):441-8. PMID: 10466974.
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  443. Domanski MJ, Exner DV, Borkowf CB, Geller NL, Rosenberg Y, Pfeffer MA. Effect of angiotensin converting enzyme inhibition on sudden cardiac death in patients following acute myocardial infarction. A meta-analysis of randomized clinical trials. J Am Coll Cardiol. 1999 Mar; 33(3):598-604. PMID: 10080457.
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  444. Rohde LE, Aikawa M, Cheng GC, Sukhova G, Solomon SD, Libby P, Pfeffer J, Pfeffer MA, Lee RT. Echocardiography-derived left ventricular end-systolic regional wall stress and matrix remodeling after experimental myocardial infarction. J Am Coll Cardiol. 1999 Mar; 33(3):835-42. PMID: 10080489.
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  445. Chae CU, Pfeffer MA, Glynn RJ, Mitchell GF, Taylor JO, Hennekens CH. Increased pulse pressure and risk of heart failure in the elderly. JAMA. 1999 Feb 17; 281(7):634-9. PMID: 10029125.
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  446. Plehn JF, Davis BR, Sacks FM, Rouleau JL, Pfeffer MA, Bernstein V, Cuddy TE, Moyé LA, Piller LB, Rutherford J, Simpson LM, Braunwald E. Reduction of stroke incidence after myocardial infarction with pravastatin: the Cholesterol and Recurrent Events (CARE) study. The Care Investigators. Circulation. 1999 Jan 19; 99(2):216-23. PMID: 9892586.
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  454. McConnell TR, Menapace FJ, Hartley LH, Pfeffer MA. Captopril reduces the VE/VCO2 ratio in myocardial infarction patients with low ejection fraction. Chest. 1998 Nov; 114(5):1289-94. PMID: 9824003.
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  455. Blanchard A, Pfeffer MA. Diagnosis and management of coronary artery disease. Am J Kidney Dis. 1998 Nov; 32(5 Suppl 3):S101-11. PMID: 9820469.
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  456. Levey AS, Beto JA, Coronado BE, Eknoyan G, Foley RN, Kasiske BL, Klag MJ, Mailloux LU, Manske CL, Meyer KB, Parfrey PS, Pfeffer MA, Wenger NK, Wilson PW, Wright JT. Controlling the epidemic of cardiovascular disease in chronic renal disease: what do we know? What do we need to learn? Where do we go from here? National Kidney Foundation Task Force on Cardiovascular Disease. Am J Kidney Dis. 1998 Nov; 32(5):853-906. PMID: 9820460.
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  457. Vantrimpont P, Rouleau JL, Ciampi A, Harel F, de Champlain J, Bichet D, Moyé LA, Pfeffer M. Two-year time course and significance of neurohumoral activation in the Survival and Ventricular Enlargement (SAVE) Study. Eur Heart J. 1998 Oct; 19(10):1552-63. PMID: 9820995.
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  458. Pfeffer M, Kühn R, Krug L, Korf HW, Stehle JH. Rhythmic variation in beta1-adrenergic receptor mRNA levels in the rat pineal gland: circadian and developmental regulation. Eur J Neurosci. 1998 Sep; 10(9):2896-904. PMID: 9758159.
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  462. Opitz CF, Finn PV, Pfeffer MA, Mitchell GF, Pfeffer JM. Effects of reperfusion on arrhythmias and death after coronary artery occlusion in the rat: increased electrical stability independent of myocardial salvage. J Am Coll Cardiol. 1998 Jul; 32(1):261-7. PMID: 9669279.
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  463. Pfeffer MA. ACE inhibitors in acute myocardial infarction: patient selection and timing. Circulation. 1998 Jun 09; 97(22):2192-4. PMID: 9631866.
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  464. Pfeffer M, Stehle JH. Ontogeny of a diurnal rhythm in arylalkylamine-N-acetyltransferase mRNA in rat pineal gland. Neurosci Lett. 1998 Jun 05; 248(3):163-6. PMID: 9654334.
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  466. Hager WD, Davis BR, Riba A, Moye LA, Wun CC, Rouleau JL, Lamas GA, Pfeffer MA. Absence of a deleterious effect of calcium channel blockers in patients with left ventricular dysfunction after myocardial infarction: The SAVE Study Experience. SAVE Investigators. Survival and Ventricular Enlargement. Am Heart J. 1998 Mar; 135(3):406-13. PMID: 9506325.
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  467. Teerlink JR, Pfeffer JM, Pfeffer MA. Effect of left ventricular sphericity on the evolution of ventricular dysfunction in rats with diffuse isoproterenol-induced myocardial necrosis. J Card Fail. 1998 Mar; 4(1):45-56. PMID: 9573503.
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  469. Pfeffer MA. Rampiril reduced long-term mortality in patients with clinical heart failure following acute MI. Evid Based Cardiovasc Med. 1997 Dec; 1(4):104. PMID: 16379760.
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  471. Mitchell GF, Pfeffer JM, Pfeffer MA. The heart and conduit vessels in hypertension. Med Clin North Am. 1997 Nov; 81(6):1247-71. PMID: 9356597.
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  473. Greaves SC, Zhi G, Lee RT, Solomon SD, MacFadyen J, Rapaport E, Menapace FJ, Rouleau JL, Pfeffer MA. Incidence and natural history of left ventricular thrombus following anterior wall acute myocardial infarction. Am J Cardiol. 1997 Aug 15; 80(4):442-8. PMID: 9285655.
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  474. Lamas GA, Mitchell GF, Flaker GC, Smith SC, Gersh BJ, Basta L, Moyé L, Braunwald E, Pfeffer MA. Clinical significance of mitral regurgitation after acute myocardial infarction. Survival and Ventricular Enlargement Investigators. Circulation. 1997 Aug 05; 96(3):827-33. PMID: 9264489.
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  484. Stehle JH, Pfeffer M, Kühn R, Korf HW. Light-induced expression of transcription factor ICER (inducible cAMP early repressor) in rat suprachiasmatic nucleus is phase-restricted. Neurosci Lett. 1996 Oct 18; 217(2-3):169-72. PMID: 8916099.
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  487. Rocco TP, Pfeffer MA. A challenge to the nuclear cardiology laboratory: imaging goals in patients after infarction. J Nucl Cardiol. 1996 Jul-Aug; 3(4):358-62. PMID: 8799257.
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  546. Smith TW, Pfeffer MA. The rationale for combined use of diuretics, digitalis, and vasodilators in congestive heart failure. Cardiovasc Drugs Ther. 1989 Mar; 3(1):13-7. PMID: 2487518.
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  547. Pfeffer MA, Lamas GA, Vaughan DE, Parisi AF, Braunwald E. Effect of captopril on progressive ventricular dilatation after anterior myocardial infarction. N Engl J Med. 1988 Jul 14; 319(2):80-6. PMID: 2967917.
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  548. Pfeffer M. Gamma variate fits to pharmacokinetic data. Eur J Drug Metab Pharmacokinet. 1988 Jul-Sep; 13(3):155-9. PMID: 3240761.
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  549. Lamas GA, Vaughan DE, Pfeffer MA. Left ventricular thrombus formation after first anterior wall acute myocardial infarction. Am J Cardiol. 1988 Jul 01; 62(1):31-5. PMID: 3381753.
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  550. Pfeffer JM, Pfeffer MA. Angiotensin converting enzyme inhibition and ventricular remodeling in heart failure. Am J Med. 1988 Mar 11; 84(3A):37-44. PMID: 3064598.
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  551. Caccia S, Vigano GL, Mingardi G, Garattini S, Gammans RE, Placchi M, Mayol RF, Pfeffer M. Clinical pharmacokinetics of oral buspirone in patients with impaired renal function. Clin Pharmacokinet. 1988 Mar; 14(3):171-7. PMID: 3370902.
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  552. Lee RT, Bloch KD, Pfeffer JM, Pfeffer MA, Neer EJ, Seidman CE. Atrial natriuretic factor gene expression in ventricles of rats with spontaneous biventricular hypertrophy. J Clin Invest. 1988 Feb; 81(2):431-4. PMID: 2963021; PMCID: PMC329587.
  553. Paul E, Pfeffer M, Bödeker RH. Effect of terfenadine and ranitidine on histamine and suxamethonium wheals. Eur J Clin Pharmacol. 1988; 34(6):591-4. PMID: 3139429.
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  554. Dalhoff K, Poulsen HE, Garred P, Placchi M, Gammans RE, Mayol RF, Pfeffer M. Buspirone pharmacokinetics in patients with cirrhosis. Br J Clin Pharmacol. 1987 Oct; 24(4):547-50. PMID: 3689635; PMCID: PMC1386319.
  555. Pfeffer MA, Pfeffer JM. Ventricular enlargement and reduced survival after myocardial infarction. Circulation. 1987 May; 75(5 Pt 2):IV93-7. PMID: 2952370.
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  556. Ichikawa I, Kon V, Pfeffer MA, Pfeffer JM, Brenner BM. Role of angiotensin II in the altered renal function of heart failure. Kidney Int Suppl. 1987 May; 20:S213-5. PMID: 3474472.
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  557. Pfeffer MA, Pfeffer JM. Ventricular enlargement following a myocardial infarction. J Cardiovasc Pharmacol. 1987; 9 Suppl 2:S18-20. PMID: 2441193.
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  558. Pfeffer JM, Pfeffer MA, Braunwald E. Hemodynamic benefits and prolonged survival with long-term captopril therapy in rats with myocardial infarction and heart failure. Circulation. 1987 Jan; 75(1 Pt 2):I149-55. PMID: 3539404.
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  559. Nakamura Y, Bing OH, Wiegner AW, Konishi T, Apstein CS, Pfeffer MA, Kawai C. Effects of hypertrophy and allylamine-induced fibrosis on mechanical properties of isolated rat heart muscles with references to the pumping function of the intact heart in the same models. Jpn Circ J. 1986 Oct; 50(10):998-1006. PMID: 2949093.
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  560. McKay RG, Pfeffer MA, Pasternak RC, Markis JE, Come PC, Nakao S, Alderman JD, Ferguson JJ, Safian RD, Grossman W. Left ventricular remodeling after myocardial infarction: a corollary to infarct expansion. Circulation. 1986 Oct; 74(4):693-702. PMID: 3757183.
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  561. Lamas GA, Pfeffer MA. Increased left ventricular volume following myocardial infarction in man. Am Heart J. 1986 Jan; 111(1):30-5. PMID: 3946157.
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  562. Fletcher PJ, Pfeffer JM, Pfeffer MA. Altered sensitivity to increases in vascular resistance in rats with hypertension and myocardial infarction. Am Heart J. 1986 Jan; 111(1):120-7. PMID: 3946139.
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  563. Pfeffer MA, Pfeffer JM, Steinberg C, Finn P. Survival after an experimental myocardial infarction: beneficial effects of long-term therapy with captopril. Circulation. 1985 Aug; 72(2):406-12. PMID: 3891136.
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  564. Bittl JA, Pfeffer MA, Lewis RA, Mehrotra MM, Corey EJ, Austen KF. Mechanism of the negative inotropic action of leukotrienes C4 and D4 on isolated rat heart. Cardiovasc Res. 1985 Jul; 19(7):426-32. PMID: 4016819.
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  565. Pfeffer JM, Pfeffer MA, Braunwald E. Influence of chronic captopril therapy on the infarcted left ventricle of the rat. Circ Res. 1985 Jul; 57(1):84-95. PMID: 3891127.
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  566. Pfeffer MA, Pfeffer JM. Left ventricular hypertrophy and pressure generating capacity in aging genetically hypertensive rats. J Cardiovasc Pharmacol. 1985; 7 Suppl 2:S41-5. PMID: 2409368.
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  567. Ichikawa I, Pfeffer JM, Pfeffer MA, Hostetter TH, Brenner BM. Role of angiotensin II in the altered renal function of congestive heart failure. Circ Res. 1984 Nov; 55(5):669-75. PMID: 6091942.
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  568. Brenner BM, Duchin KL, Ichikawa I, Pfeffer J, Pfeffer M. Comparative effects of propranolol and nadolol on renal blood flow in normal rats and rats with congestive heart failure. Am Heart J. 1984 Oct; 108(4 Pt 2):1144-7. PMID: 6148876.
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  569. Pfeffer MA, Pfeffer J, Mirsky I, Iwai J. Cardiac hypertrophy and performance of Dahl hypertensive rats on graded salt diets. Hypertension. 1984 Jul-Aug; 6(4):475-81. PMID: 6235189.
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  570. Wajsman Z, Dhafir RA, Pfeffer M, MacDonald S, Block A, Dragone N, Pontes JE. Studies of mitomycin C absorption after intravesical treatment of superficial bladder tumors. J Urol. 1984 Jul; 132(1):30-3. PMID: 6427484.
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  571. Pfeffer JM, Pfeffer MA, Fletcher PJ, Braunwald E. Ventricular performance in rats with myocardial infarction and failure. Am J Med. 1984 May 31; 76(5B):99-103. PMID: 6233904.
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  572. Badr KF, Baylis C, Pfeffer JM, Pfeffer MA, Soberman RJ, Lewis RA, Austen KF, Corey EJ, Brenner BM. Renal and systemic hemodynamic responses to intravenous infusion of leukotriene C4 in the rat. Circ Res. 1984 May; 54(5):492-9. PMID: 6722998.
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  573. Pfeffer MA, Pfeffer JM. Pharmacologic regression of cardiac hypertrophy in experimental hypertension. J Cardiovasc Pharmacol. 1984; 6 Suppl 6:S865-9. PMID: 6084141.
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  574. Mirsky I, Pfeffer JM, Pfeffer MA, Braunwald E. The contractile state as the major determinant in the evolution of left ventricular dysfunction in the spontaneously hypertensive rat. Circ Res. 1983 Dec; 53(6):767-78. PMID: 6640863.
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  575. Pfeffer MA, Pfeffer JM. Blood pressure and left ventricular dysfunction in the spontaneously hypertensive rat. Fed Proc. 1983 Jul; 42(10):2698-702. PMID: 6862035.
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  576. Hostetter TH, Pfeffer JM, Pfeffer MA, Dworkin LD, Braunwald E, Brenner BM. Cardiorenal hemodynamics and sodium excretion in rats with myocardial infarction. Am J Physiol. 1983 Jul; 245(1):H98-103. PMID: 6869568.
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  577. Pfeffer MA, Pfeffer JM, Lewis RA, Braunwald E, Corey EJ, Austen KF. Systemic hemodynamic effects of leukotrienes C4 and D4 in the rat. Am J Physiol. 1983 Apr; 244(4):H628-33. PMID: 6837761.
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  578. Pfeffer JM, Pfeffer MA, Mirsky I, Braunwald E. Prevention of the development of heart failure and the regression of cardiac hypertrophy by captopril in the spontaneously hypertensive rat. Eur Heart J. 1983 Jan; 4 Suppl A:143-8. PMID: 6220893.
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  579. Fletcher PJ, Pfeffer JM, Pfeffer MA, Braunwald E. Effects of hypertension on cardiac performance in rats with myocardial infarction. Am J Cardiol. 1982 Sep; 50(3):488-96. PMID: 7113932.
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  580. Pfeffer JM, Pfeffer MA, Fletcher P, Fishbein MC, Braunwald E. Favorable effects of therapy on cardiac performance in spontaneously hypertensive rats. Am J Physiol. 1982 May; 242(5):H776-84. PMID: 7081448.
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  581. Pfeffer JM, Pfeffer MA, Mirsky I, Braunwald E. Regression of left ventricular hypertrophy and prevention of left ventricular dysfunction by captopril in the spontaneously hypertensive rat. Proc Natl Acad Sci U S A. 1982 May; 79(10):3310-4. PMID: 6212929; PMCID: PMC346405.
  582. Kleber FX, Pfeffer MA, Pfeffer JM. Alterations in the electrocardiogram of spontaneously hypertensive rats by chronic antihypertensive therapy with captopril. Clin Exp Hypertens A. 1982; 4(6):977-87. PMID: 6212168.
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  583. Fletcher PJ, Pfeffer JM, Pfeffer MA, Braunwald E. Left ventricular diastolic pressure-volume relations in rats with healed myocardial infarction. Effects on systolic function. Circ Res. 1981 Sep; 49(3):618-26. PMID: 7261261.
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  584. Fletcher PJ, Pfeffer JM, Pfeffer MA, Braunwald E. Myocardial infarction in experimental hypertension in rats: mechanism of the reduction in blood pressure. Clin Sci (Lond). 1980 Dec; 59 Suppl 6:385s-387s. PMID: 7449286.
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  585. Pfeffer M, Pfeffer J. Hypertension. Hypertension. 1980 Sep-Oct; 2(5):719-21. PMID: 6448223.
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  586. Spadaro J, Fishbein MC, Hare C, Pfeffer MA, Maroko PR. Characterization of myocardial infarcts in the rat. Arch Pathol Lab Med. 1980 Apr; 104(4):179-83. PMID: 6892678.
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  587. Pfeffer J, Pfeffer M, Fletcher P, Braunwald E. Alterations of cardiac performance in rats with established spontaneous hypertension. Am J Cardiol. 1979 Oct 22; 44(5):994-8. PMID: 158974.
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  588. Pfeffer JM, Pfeffer MA, Fishbein MC, Frohlich ED. Cardiac function and morphology with aging in the spontaneously hypertensive rat. Am J Physiol. 1979 Oct; 237(4):H461-8. PMID: 495731.
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  589. Pfeffer MA, Pfeffer JM, Dunn FG, Nishiyama K, Tsuchiya M, Frohlich ED. Natural biventricular hypertrophy in normotensive rats. I. Physical and hemodynamic characteristics. Am J Physiol. 1979 Apr; 236(4):H640-3. PMID: 155407.
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  590. Pfeffer MA, Pfeffer JM, Fishbein MC, Fletcher PJ, Spadaro J, Kloner RA, Braunwald E. Myocardial infarct size and ventricular function in rats. Circ Res. 1979 Apr; 44(4):503-12. PMID: 428047.
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  591. Pfeffer MA, Ferrell BA, Pfeffer JM, Weiss AK, Fishbein MC, Frohlich ED. Ventricular morphology and pumping ability of exercised spontaneously hypertensive rats. Am J Physiol. 1978 Aug; 235(2):H193-9. PMID: 150800.
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  592. Dunn FG, Pfeffer MA, Frohlich ED. ECG alterations with progressive left ventricular hypertrophy in spontaneous hypertension. Clin Exp Hypertens. 1978; 1(1):67-86. PMID: 158496.
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  593. Nishiyama K, Nishiyama A, Pfeffer MA, Frohlich ED. Systemic and regional flow distribution in normotensive and spontaneously hypertensive young rats subjected to lifetime beta-adrenergic receptor blockade. Blood Vessels. 1978; 15(6):333-47. PMID: 708888.
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  594. Pfeffer MA, Pfeffer JM, Weiss AK, Frohlich ED. Development of SHR hypertension and cardiac hypertrophy during prolonged beta blockade. Am J Physiol. 1977 Jun; 232(6):H639-644. PMID: 18018.
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  595. Peterson AL, Pfeffer MA, Weiss AK, Frohlich ED. Development of a hypertensive strain of Wistar rats from previously normotensive but labile normals. J Lab Clin Med. 1977 Jun; 89(6):1163-7. PMID: 864299.
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  596. Pfeffer MA, Pfeffer JM, Frohlich ED. Pumping ability of the hypertrophying left ventricle of the spontaneously hypertensive rat. Circ Res. 1976 May; 38(5):423-9. PMID: 131652.
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  597. Frohlich ED, Pfeffer MA. Adrenergic mechanisms in human hypertension and in spontaneously hypertensive rats. Clin Sci Mol Med Suppl. 1975 Jun; 2:225s-238s. PMID: 1077770.
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  598. Pfeffer JM, Pfeffer MA, Frohlich ED. Hemodynamic effects of mebutamate in spontaneously hypertensive rats. Arch Int Pharmacodyn Ther. 1975 May; 215(1):133-8. PMID: 1156042.
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  599. Lohmöller G, Lohmöller R, Pfeffer MA, Pfeffer JM, Frohlich ED. Mechanism of immediate hemodynamic effects of chlorothiazide. Am Heart J. 1975 Apr; 89(4):487-92. PMID: 1114981.
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  600. Pfeffer MA, Pfeffer JM, Frohlich ED. Hemodynamics of the spontaneously hypertensive rat: effects of isoproterenol. Proc Soc Exp Biol Med. 1974 Mar; 145(3):1025-30. PMID: 4818578.
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  601. Mandal AK, Frohlich ED, Chrysant K, Pfeffer MA, Yunice A, Nordquist JA. Ultrastructural analysis of renal papillary interstitial cell of spontaneously hypertensive rats. J Lab Clin Med. 1974 Feb; 83(2):256-62. PMID: 4810953.
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  602. Weinstein SH, Pfeffer M, Schor JM, Franklin L, Mintz M, Tutko ER. Abortion and distribution of naloxone in rats after oral and intravenous administration. J Pharm Sci. 1973 Sep; 62(9):1416-9. PMID: 4743082.
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  603. Pfeffer MA, Frohlich ED. Hemodynamic and myocardial function in young and old normotensive and spontaneously hypertensive rats. Circ Res. 1973 May 05; 32:Suppl 1:28-38. PMID: 4712514.
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  604. Pfeffer MA, Frohlich ED. Hemodynamics of spontaneously hypertensive rats. I. Effects of pressure elevation. Am J Physiol. 1973 May; 224(5):1066-71. PMID: 4700624.
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  605. Pfeffer MA, Pfeffer JM, Frohlich ED. Ventricular function during early left ventricular hypertrophy of the intact spontaneously hypertensive rat. Recent Adv Stud Cardiac Struct Metab. 1973; 3:665-74. PMID: 4283201.
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  606. Treat E, Ulano H, Pfeffer M, Massion W, Shanbour LL, Jacobson ED. Effects of ouabain on cardiac output and pulmonary blood flow in dogs. Am Heart J. 1972 Sep; 84(3):371-6. PMID: 5075645.
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  607. Frohlich ED, Thurman AE, Pfeffer MA, Brobmann GF, Jacobson ED. Altered vascular responsiveness: initial hypotensive mechanism of thiazide diuretics. 1. Proc Soc Exp Biol Med. 1972 Sep; 140(4):1190-6. PMID: 4341556.
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  608. Pfeffer MA, Frohlich ED. Electromagnetic flowmetry in anesthetized rats. J Appl Physiol. 1972 Jul; 33(1):137-40. PMID: 5037398.
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  609. Frohlich ED, Pfeffer MA, Weiss AK, Brecher GA. Variability of arterial pressure in normotensive and spontaneously hypertensive rats. Proc Soc Exp Biol Med. 1972 May; 140(1):145-8. PMID: 5033085.
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  610. Pfeffer JM, Pfeffer MA, Frohlich ED. Validity of an indirect tail-cuff method for determining systolic arterial pressure in unanesthetized normotensive and spontaneously hypertensive rats. J Lab Clin Med. 1971 Dec; 78(6):957-62. PMID: 5131859.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.