Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Gyorgy Frendl, Ph.D., M.D.

Title
Institution
Department
Address
Phone
Fax

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Frendl G. In Search of Answers and Technology to Better Identify the Bleeding and the Hypercoagulable Patient Phenotype-The Need for Improved Assessment of Deranged Coagulation Beyond Our Current Coagulation Tests. Crit Care Med. 2019 Jun; 47(6):876-877. PMID: 31095021.
    Citations:    
  2. Mizuguchi KA, Shekar P, Frendl G. Discovery of biomarkers that diagnose kidney disease progression and novel patient management strategies needed now to prevent progressive kidney disease. J Thorac Cardiovasc Surg. 2018 Dec; 156(6):2181-2182. PMID: 30195592.
    Citations:    Fields:    
  3. Rhee Y, Palmer LJ, Okamoto K, Gemunden S, Hammouda K, Kemble SK, Lin MY, Lolans K, Fogg L, Guanaga D, Yokoe DS, Weinstein RA, Frendl G, Hayden MK. Differential Effects of Chlorhexidine Skin Cleansing Methods on Residual Chlorhexidine Skin Concentrations and Bacterial Recovery. Infect Control Hosp Epidemiol. 2018 04; 39(4):405-411. PMID: 29493475.
    Citations:    Fields:    
  4. Mizuguchi KA, Huang CC, Shempp I, Wang J, Shekar P, Frendl G. Predicting kidney disease progression in patients with acute kidney injury after cardiac surgery. J Thorac Cardiovasc Surg. 2018 Jun; 155(6):2455-2463.e5. PMID: 29548590.
    Citations:    Fields:    
  5. Elias KM, Fendler W, Stawiski K, Fiascone SJ, Vitonis AF, Berkowitz RS, Frendl G, Konstantinopoulos P, Crum CP, Kedzierska M, Cramer DW, Chowdhury D. Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer. Elife. 2017 10 31; 6. PMID: 29087294.
    Citations: 2     Fields:    Translation:Humans
  6. Shih YN, Chen YT, Chu H, Shih CJ, Ou SM, Hsu YT, Chen RC, Quraishi SA, Aisiku IP, Seethala RR, Frendl G, Hou PC. Association of pre-hospital theophylline use and mortality in chronic obstructive pulmonary disease patients with sepsis. Respir Med. 2017 04; 125:33-38. PMID: 28340860.
    Citations: 1     Fields:    Translation:Humans
  7. Fernandez-Bustamante A, Frendl G, Sprung J, Kor DJ, Subramaniam B, Martinez Ruiz R, Lee JW, Henderson WG, Moss A, Mehdiratta N, Colwell MM, Bartels K, Kolodzie K, Giquel J, Vidal Melo MF. Postoperative Pulmonary Complications, Early Mortality, and Hospital Stay Following Noncardiothoracic Surgery: A Multicenter Study by the Perioperative Research Network Investigators. JAMA Surg. 2017 02 01; 152(2):157-166. PMID: 27829093.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  8. Seethala RR, Hou PC, Aisiku IP, Frendl G, Park PK, Mikkelsen ME, Chang SY, Gajic O, Sevransky J. Early risk factors and the role of fluid administration in developing acute respiratory distress syndrome in septic patients. Ann Intensive Care. 2017 Dec; 7(1):11. PMID: 28116595.
    Citations: 1     
  9. Shih YN, Chen YT, Shih CJ, Ou SM, Hsu YT, Chen RC, Aisiku IP, Seethala RR, Frendl G, Hou PC. Association of weekend effect with early mortality in severe sepsis patients over time. J Infect. 2017 04; 74(4):345-351. PMID: 28025161.
    Citations: 3     Fields:    Translation:Humans
  10. Frendl G. The Mystery of Delirium. Could Biomarkers of Endothelial Activation Reveal the Secrets? Crit Care Med. 2016 09; 44(9):1795-6. PMID: 27526004.
    Citations:    Fields:    Translation:Humans
  11. Edrich T, Stopfkuchen-Evans M, Scheiermann P, Heim M, Chan W, Stone MB, Dankl D, Aichner J, Hinzmann D, Song P, Szabo AL, Frendl G, Vlassakov K, Varelmann D. A Comparison of Web-Based with Traditional Classroom-Based Training of Lung Ultrasound for the Exclusion of Pneumothorax. Anesth Analg. 2016 07; 123(1):123-8. PMID: 27159073.
    Citations: 3     Fields:    Translation:Humans
  12. Pavkovic M, Robinson-Cohen C, Chua AS, Nicoara O, Cárdenas-González M, Bijol V, Ramachandran K, Hampson L, Pirmohamed M, Antoine DJ, Frendl G, Himmelfarb J, Waikar SS, Vaidya VS. Detection of Drug-Induced Acute Kidney Injury in Humans Using Urinary KIM-1, miR-21, -200c, and -423. Toxicol Sci. 2016 07; 152(1):205-13. PMID: 27122240.
    Citations: 7     Fields:    Translation:HumansCells
  13. Ng JM, Sugarbaker DJ, Bienfang DC, Richards WG, DaSilva MC, Frendl G, Hartigan PM. Perioperative Ischemic Optic Neuropathy Following Extrapleural Pneumonectomy. J Cardiothorac Vasc Anesth. 2016 Dec; 30(6):1645-1648. PMID: 27178100.
    Citations:    Fields:    Translation:Humans
  14. Elias KM, Kang S, Liu X, Horowitz NS, Berkowitz RS, Frendl G. Erratum to: Anesthetic Selection and Disease-Free Survival Following Optimal Primary Cytoreductive Surgery for Stage III Epithelial Ovarian Cancer. Ann Surg Oncol. 2015 Dec; 22 Suppl 3:S1606-7. PMID: 25631066.
    Citations:    Fields:    
  15. Elias KM, Kang S, Liu X, Horowitz NS, Berkowitz RS, Frendl G. Erratum to: Anesthetic Selection and Disease-Free Survival Following Optimal Primary Cytoreductive Surgery for Stage III Epithelial Ovarian Cancer. Ann Surg Oncol. 2015 Dec; 22 Suppl 3:S1611. PMID: 25821001.
    Citations:    Fields:    
  16. Edrich T, Frendl G, Michaud G, Paschalidis ICh. Heparin requirements for full anticoagulation are higher for patients on dabigatran than for those on warfarin - a model-based study. Clin Pharmacol. 2015; 7:19-27. PMID: 25709508.
    Citations: 1     
  17. Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Rawn JD, Frendl G, Waikar SS. Increased plasma catalytic iron in patients may mediate acute kidney injury and death following cardiac surgery. Kidney Int. 2015 May; 87(5):1046-54. PMID: 25565307.
    Citations: 9     Fields:    Translation:Humans
  18. Elias KM, Kang S, Liu X, Horowitz NS, Berkowitz RS, Frendl G. Anesthetic selection and disease-free survival following optimal primary cytoreductive surgery for stage III epithelial ovarian cancer. Ann Surg Oncol. 2015 Apr; 22(4):1341-8. PMID: 25287437.
    Citations: 6     Fields:    Translation:Humans
  19. Frendl G, Sodickson AC, Chung MK, Waldo AL, Gersh BJ, Tisdale JE, Calkins H, Aranki S, Kaneko T, Cassivi S, Smith SC, Darbar D, Wee JO, Waddell TK, Amar D, Adler D. 2014 AATS guidelines for the prevention and management of perioperative atrial fibrillation and flutter for thoracic surgical procedures. J Thorac Cardiovasc Surg. 2014 Sep; 148(3):e153-93. PMID: 25129609.
    Citations: 12     Fields:    Translation:Humans
  20. Frendl G, Sodickson AC, Chung MK, Waldo AL, Gersh BJ, Tisdale JE, Calkins H, Aranki S, Kaneko T, Cassivi S, Smith SC, Darbar D, Wee JO, Waddell TK, Amar D, Adler D. 2014 AATS guidelines for the prevention and management of perioperative atrial fibrillation and flutter for thoracic surgical procedures. Executive summary. J Thorac Cardiovasc Surg. 2014 Sep; 148(3):772-91. PMID: 25129583.
    Citations: 4     Fields:    Translation:Humans
  21. Rahaghi FN, Lazea D, Dihya S, San José Estépar R, Bueno R, Sugarbaker D, Frendl G, Washko GR. Preoperative pulmonary vascular morphology and its relationship to postpneumonectomy hemodynamics. Acad Radiol. 2014 Jun; 21(6):704-10. PMID: 24809312.
    Citations:    Fields:    Translation:Humans
  22. Oxman DA, Adams CD, Deluke G, Philbrook L, Ireland P, Mitani A, Panizales C, Frendl G, Rogers SO. Improving Antibiotic De-Escalation in Suspected Ventilator-Associated Pneumonia: An Observational Study With a Pharmacist-Driven Intervention. J Pharm Pract. 2015 Oct; 28(5):457-61. PMID: 24651641.
    Citations: 1     Fields:    Translation:Humans
  23. Williams M, Alban RF, Hardy JP, Oxman DA, Garcia ER, Hevelone N, Frendl G, Rogers SO. In-hospital fellow coverage reduces communication errors in the surgical intensive care unit. J Crit Care. 2014 Jun; 29(3):445-9. PMID: 24529985.
    Citations: 2     Fields:    Translation:Humans
  24. Edrich T, Seethala RR, Olenchock BA, Mizuguchi AK, Rivero JM, Beutler SS, Fox JA, Liu X, Frendl G. Providing initial transthoracic echocardiography training for anesthesiologists: simulator training is not inferior to live training. J Cardiothorac Vasc Anesth. 2014 Feb; 28(1):49-53. PMID: 24183827.
    Citations: 3     Fields:    Translation:Humans
  25. Frendl G. Benzodiazepines: revealing of the secrets of GABAA-mediated immunosuppression: GABAA subtype-specific benzodiazepines are the hope. Crit Care Med. 2013 Jul; 41(7):1807-8. PMID: 23774342.
    Citations:    
  26. Oxman DA, Issa NC, Marty FM, Patel A, Panizales CZ, Johnson NN, Licona JH, McKenna SS, Frendl G, Mentzer SJ, Jaklitsch MT, Bueno R, Colson Y, Swanson SJ, Sugarbaker DJ, Baden LR. Postoperative antibacterial prophylaxis for the prevention of infectious complications associated with tube thoracostomy in patients undergoing elective general thoracic surgery: a double-blind, placebo-controlled, randomized trial. JAMA Surg. 2013 May; 148(5):440-6. PMID: 23325435.
    Citations: 3     Fields:    Translation:Humans
  27. Edrich T, Frendl G. Simulation training for rare medications in the intensive care unit-a study with bivalirudin. Anaesth Intensive Care. 2013 Mar; 41(2):242-6. PMID: 23530791.
    Citations:    Fields:    Translation:Humans
  28. Elie-Turenne MC, Hou PC, Mitani A, Barry JM, Kao EY, Cohen JE, Frendl G, Gajic O, Gentile NT. Lung injury prediction score for the emergency department: first step towards prevention in patients at risk. Int J Emerg Med. 2012 Sep 03; 5(1):33. PMID: 22943391.
    Citations: 2     
  29. Hoffmann D, Bijol V, Krishnamoorthy A, Gonzalez VR, Frendl G, Zhang Q, Goering PL, Brown RP, Waikar SS, Vaidya VS. Fibrinogen excretion in the urine and immunoreactivity in the kidney serves as a translational biomarker for acute kidney injury. Am J Pathol. 2012 Sep; 181(3):818-28. PMID: 22819533.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  30. Zhao H, Heard SO, Mullen MT, Crawford S, Goldberg RJ, Frendl G, Lilly CM. An evaluation of the diagnostic accuracy of the 1991 American College of Chest Physicians/Society of Critical Care Medicine and the 2001 Society of Critical Care Medicine/European Society of Intensive Care Medicine/American College of Chest Physicians/American Thoracic Society/Surgical Infection Society sepsis definition. Crit Care Med. 2012 Jun; 40(6):1700-6. PMID: 22610176.
    Citations: 15     Fields:    Translation:Humans
  31. Hou PC, Elie-Turenne MC, Mitani A, Barry JM, Kao EY, Cohen JE, Frendl G, Gajic O, Gentile NT. Towards prevention of acute lung injury: frequency and outcomes of emergency department patients at-risk - a multicenter cohort study. Int J Emerg Med. 2012 May 27; 5(1):22. PMID: 22632126.
    Citations: 7     
  32. Ng SY, Sugarbaker DJ, Frendl G. Interatrial shunting after major thoracic surgery: a rare but clinically significant event. Ann Thorac Surg. 2012 May; 93(5):1647-51. PMID: 22541195.
    Citations:    Fields:    Translation:Humans
  33. Mizuguchi KA, Mitani A, Waikar SS, Ireland P, Panizales C, Deluke G, Sugarbaker DJ, Bonventre JV, Frendl G. Use of postoperative creatinine to predict sustained kidney injury in patients undergoing mesothelioma surgery. Clin J Am Soc Nephrol. 2012 Jul; 7(7):1071-8. PMID: 22537654.
    Citations: 1     Fields:    Translation:Humans
  34. Edrich T, Frendl G, Rawn JD, Paschalidis Y. Modeling the effects of bivalirudin in cardiac surgical patients. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:120-3. PMID: 22254265.
    Citations: 2     Fields:    Translation:Humans
  35. Oxman DA, Chow JK, Frendl G, Hadley S, Hershkovitz S, Ireland P, McDermott LA, Tsai K, Marty FM, Kontoyiannis DP, Golan Y. Candidaemia associated with decreased in vitro fluconazole susceptibility: is Candida speciation predictive of the susceptibility pattern? J Antimicrob Chemother. 2010 Jul; 65(7):1460-5. PMID: 20430790.
    Citations: 18     Fields:    Translation:HumansAnimals
  36. Williams M, Hevelone N, Alban RF, Hardy JP, Oxman DA, Garcia E, Thorsen C, Frendl G, Rogers SO. Measuring communication in the surgical ICU: better communication equals better care. J Am Coll Surg. 2010 Jan; 210(1):17-22. PMID: 20123326.
    Citations: 6     Fields:    
  37. Mizuguchi A, Frendl G. Multi-organ system failure. Segal S, Sikka P, Urman R, Vacanti C, editors. Essential Clinical Anesthesia. 2009.
  38. Oxman D, McKenna S, Frendl G. Nosocomial infections in essential clinical anesthesia. Segal S, Sikka P, Urman R, Vacanti C, editors. Essential Clinical Anesthesia. 2009.
  39. Williams M, Frendl G. total parenteral nutrition. Segal S, Sikka P, Urman R, Vacanti C, editors. Essential Clinical Anesthesia. 2009.
  40. Melanson SE, Szymanski T, Rogers SO, Jarolim P, Frendl G, Rawn JD, Cooper Z, Ferrigno M. Utilization of arterial blood gas measurements in a large tertiary care hospital. Am J Clin Pathol. 2007 Apr; 127(4):604-9. PMID: 17369137.
    Citations: 2     Fields:    Translation:Humans
  41. Romics L, Frendl G, Szabó G. [Cellular and molecular changes of the liver in sepsis and in systemic inflammatory response syndrome (SIRS)]. Orv Hetil. 2003 Mar 16; 144(11):499-506. PMID: 12731336.
    Citations: 1     Fields:    Translation:HumansAnimals
  42. Szabo G, Romics L, Frendl G. Liver in sepsis and systemic inflammatory response syndrome. Clin Liver Dis. 2002 Nov; 6(4):1045-66, x. PMID: 12516206.
    Citations: 35     Fields:    Translation:Humans
  43. Szabo G, Romics L, Frendl G. Liver in sepsis and systemic inflammatory response syndrome. Bonkovsky H, editor. Clinics in liver disease, hepatic manifestations of systemic diseases. 2002; 6:1045-1066.
  44. Colgan SP, Parkos CA, McGuirk D, Brady HR, Papayianni AA, Frendl G, Madara JL. Receptors involved in carbohydrate binding modulate intestinal epithelial-neutrophil interactions. J Biol Chem. 1995 May 05; 270(18):10531-9. PMID: 7537733.
    Citations: 14     Fields:    Translation:HumansCells
  45. Stahl GL, Reenstra WR, Frendl G. Complement-mediated loss of endothelium-dependent relaxation of porcine coronary arteries. Role of the terminal membrane attack complex. Circ Res. 1995 Apr; 76(4):575-83. PMID: 7534659.
    Citations: 10     Fields:    Translation:HumansAnimals
  46. Guan RJ, Reenstra W, Frendl G. RAF-1 is essential for both the LPS-induced activation of MAP kinases in macrophages and for their translocation to the nucleus. FASEB J. 1995; 9(4):A779.
  47. Frendl G, Guan RJ, Reensra W. Antisense oligonucleotide blocking of RAF-1 prevents both LPS-induced activation and nuclear translocation of MAP kinases in macrophages. J Leuk Biol. 1995; Suppl:28.
  48. Frendl G, Reenstra W, Xanthopoulos L, Kendig L, Rollins B. Macrophages are key elements of tissue destruction in a novel model of experimental colitis. FASEB J. 1995; 9(4):A1035.
  49. Frendl G, Nicholasen S, Murphy JR, LaMont JT. A novel experimental colitis model: The role of iL-2 receptor positive mucosal cells. J Leuk Biol (Suppl). 1994; 56:A22.
  50. Frendl G, Guan R, Szilvasi A, Hirsch R. MAP kinases are involved in mediating signaling from IFN, IL-3 and GM-CSF receptors in macrophages. FASEB J. 1994; 8:A744.
  51. Frendl G, Guan R. The mitogen-activated protein kinase (MAP-kinase) is a common element of multiple macrophage activation pathways: Activation of MAP kinase by LPS, GM-CSF, and other macrophage activating factors. Masihi KN, editor. Immunotherapy of infections. 1994; 423-455.
  52. Hirsch R, Nicholasen S, Murphy JR, LaMont JT, Frendl G. the role of IL-2 receptor positive cells in experimental colitis. FASEB J. 1994; 8:A1010.
  53. Jiang Y, Beller DI, Frendl G, Graves DT. Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes. J Immunol. 1992 Apr 15; 148(8):2423-8. PMID: 1348518.
    Citations: 98     Fields:    Translation:HumansCells
  54. Frendl G. Interleukin 3: from colony-stimulating factor to pluripotent immunoregulatory cytokine. Int J Immunopharmacol. 1992 Apr; 14(3):421-30. PMID: 1618595.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  55. Frendl G. Interleukin-3: From colony-stimulting factor to pluripotent immunoregulatory cytokine. Int J Immunopharmac. 1992; 14:421-430.
  56. Guan R, Frendl G, Beller DI. Lipopolysaccharide activated multiple protein kinases n macrophages. Molec Biol Cell. Suppl. 1992; 3:337a.
  57. Frendl G, Guan R, Beller DI. IFN activates the MAP kinase in murine macropahges. Molec Biol Cell Suppl. 1992; 3:148a.
  58. Frendl G, Fenton MJ, Beller DI. IL-3 regulates macrophage IL-1, IL-6 and TNF expression at the level of transcription and post-transcriptional regulation. 8th Internatl Cong Immunol., Budapest, Hungary. 1992; 148.
  59. Donnelly RP, Levine J, Hartwell DQ, Frendl G, Fenton MJ, Beller DI. Aberrant regulation of IL-1 expression in macrophages from young autoimmune-prone mice. J Immunol. 1990 Nov 15; 145(10):3231-9. PMID: 2230116.
    Citations: 14     Fields:    Translation:AnimalsCells
  60. Frendl G, Fenton MJ, Beller DI. Regulation of macrophage activation by IL-3. II. IL-3 and lipopolysaccharide act synergistically in the regulation of IL-1 expression. J Immunol. 1990 May 01; 144(9):3400-10. PMID: 2109777.
    Citations: 6     Fields:    Translation:AnimalsCells
  61. Frendl G, Beller DI. Regulation of macrophage activation by IL-3. I. IL-3 functions as a macrophage-activating factor with unique properties, inducing Ia and lymphocyte function-associated antigen-1 but not cytotoxicity. J Immunol. 1990 May 01; 144(9):3392-9. PMID: 2158509.
    Citations: 13     Fields:    Translation:AnimalsCells
  62. Bodolay E, Lukács K, Frendl G, Szabó G, Arató G, Szegedi G. Polymorphonuclear functions in patients with mixed connective tissue disease. Allergol Immunopathol (Madr). 1989 Jul-Aug; 17(4):205-7. PMID: 2530862.
    Citations:    Fields:    Translation:HumansCells
  63. Bodolay E, Lukács K, Szabó G, Frendl G, Ben T, Szegedi G. Monocyte functions in patients with mixed connective tissue disease. Allergol Immunopathol (Madr). 1989 Jan-Feb; 17(1):39-43. PMID: 2526572.
    Citations:    Fields:    Translation:HumansCells
  64. Frendl G, Beller DI. Ia inducing activity of macrophage origin. FASEB J. 1988; 2:A685.
  65. Frendl G, et al. Stimulation of neutrophil functions by lymphokines adn synthetic stimulators. Immunobiologics & their application. Budapest, Hungary. 1985; 21.
  66. Szabo G, Lukacs G, Frendl G, et al. Stimulating effect of tetrapeptide tuftsin in autoimmune and malignant diseases. Immunobiologics & Their Application. Budapest, Hungary. 1985; 27.
  67. Lukács K, Kávai M, Berényi E, Frendl G, Schröder I, Szegedi G. Effect of dialysable leukocyte extract on the mononuclear leukocytes in Hodgkin's disease. Haematologia (Budap). 1985; 18(2):105-13. PMID: 3161810.
    Citations:    Fields:    Translation:HumansCells
  68. Lukács K, Frendl G, Berényi E, Kávai M, Szabó G, Szegedi G. Monocyte chemotaxis and effect of levamisole in Hodgkin's disease. Acta Med Acad Sci Hung. 1980; 37(2):145-50. PMID: 7457021.
    Citations: 4     Fields:    Translation:HumansCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Frendl's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (283)
Explore
_
Co-Authors (54)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.