Harvard Catalyst Profiles

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Andrew Eugene Hermann Elia, M.D., Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhou C, Elia AE, Naylor ML, Dephoure N, Ballif BA, Goel G, Xu Q, Ng A, Chou DM, Xavier RJ, Gygi SP, Elledge SJ. Profiling DNA damage-induced phosphorylation in budding yeast reveals diverse signaling networks. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):E3667-75. PMID: 27298372; PMCID: PMC4932963.
    Citations: 24     Fields:    Translation:AnimalsCells
  2. Willis NA, Zhou C, Elia AE, Murray JM, Carr AM, Elledge SJ, Rhind N. Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks. Proc Natl Acad Sci U S A. 2016 06 28; 113(26):E3676-85. PMID: 27298342; PMCID: PMC4932944.
    Citations: 8     Fields:    Translation:AnimalsCells
  3. Elia AE, Wang DC, Willis NA, Boardman AP, Hajdu I, Adeyemi RO, Lowry E, Gygi SP, Scully R, Elledge SJ. RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks. Mol Cell. 2015 Oct 15; 60(2):280-93. PMID: 26474068; PMCID: PMC4609029.
    Citations: 62     Fields:    Translation:HumansCells
  4. Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ. Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response. Mol Cell. 2015 Sep 03; 59(5):867-81. PMID: 26051181; PMCID: PMC4560960.
    Citations: 152     Fields:    Translation:HumansCells
  5. Gao J, Kim HM, Elia AE, Elledge SJ, Colaiácovo MP. NatB domain-containing CRA-1 antagonizes hydrolase ACER-1 linking acetyl-CoA metabolism to the initiation of recombination during C. elegans meiosis. PLoS Genet. 2015 Mar; 11(3):e1005029. PMID: 25768301.
    Citations: 17     Fields:    Translation:AnimalsCells
  6. John SP, Chin CR, Perreira JM, Feeley EM, Aker AM, Savidis G, Smith SE, Elia AE, Everitt AR, Vora M, Pertel T, Elledge SJ, Kellam P, Brass AL. The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication. J Virol. 2013 Jul; 87(14):7837-52. PMID: 23658454.
    Citations: 119     Fields:    Translation:HumansAnimalsCells
  7. Pavlova NN, Pallasch C, Elia AE, Braun CJ, Westbrook TF, Hemann M, Elledge SJ. A role for PVRL4-driven cell-cell interactions in tumorigenesis. Elife. 2013 Apr 30; 2:e00358. PMID: 23682311.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  8. Wang CI, Alekseyenko AA, LeRoy G, Elia AE, Gorchakov AA, Britton LM, Elledge SJ, Kharchenko PV, Garcia BA, Kuroda MI. Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Nat Struct Mol Biol. 2013 Feb; 20(2):202-9. PMID: 23295261.
    Citations: 70     Fields:    Translation:AnimalsCells
  9. Elia AE, Elledge SJ. BRCA1 as tumor suppressor: lord without its RING? Breast Cancer Res. 2012 Apr 10; 14(2):306. PMID: 22494569.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  10. Hao Z, Duncan GS, Su YW, Li WY, Silvester J, Hong C, You H, Brenner D, Gorrini C, Haight J, Wakeham A, You-Ten A, McCracken S, Elia A, Li Q, Detmar J, Jurisicova A, Hobeika E, Reth M, Sheng Y, Lang PA, Ohashi PS, Zhong Q, Wang X, Mak TW. The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis. J Exp Med. 2012 Jan 16; 209(1):173-86. PMID: 22213803; PMCID: PMC3260869.
    Citations: 40     Fields:    Translation:AnimalsCells
  11. Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ. Global identification of modular cullin-RING ligase substrates. Cell. 2011 Oct 14; 147(2):459-74. PMID: 21963094.
    Citations: 235     Fields:    Translation:HumansCells
  12. Emanuele MJ, Ciccia A, Elia AE, Elledge SJ. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate. Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24):9845-50. PMID: 21628590.
    Citations: 58     Fields:    Translation:HumansCells
  13. Hao Z, Duncan GS, Seagal J, Su YW, Hong C, Haight J, Chen NJ, Elia A, Wakeham A, Li WY, Liepa J, Wood GA, Casola S, Rajewsky K, Mak TW. Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis. Immunity. 2008 Oct 17; 29(4):615-27. PMID: 18835195.
    Citations: 100     Fields:    Translation:AnimalsCells
  14. Elia A, Constantinou C, Clemens MJ. Effects of protein phosphorylation on ubiquitination and stability of the translational inhibitor protein 4E-BP1. Oncogene. 2008 Jan 31; 27(6):811-22. PMID: 17653084.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  15. Elia AE, Shih HA, Loeffler JS. Stereotactic radiation treatment for benign meningiomas. Neurosurg Focus. 2007; 23(4):E5. PMID: 17961042.
    Citations: 23     Fields:    Translation:Humans
  16. Mah AS, Elia AE, Devgan G, Ptacek J, Schutkowski M, Snyder M, Yaffe MB, Deshaies RJ. Substrate specificity analysis of protein kinase complex Dbf2-Mob1 by peptide library and proteome array screening. BMC Biochem. 2005 Oct 21; 6:22. PMID: 16242037; PMCID: PMC1277818.
    Citations: 52     Fields:    Translation:AnimalsCells
  17. Hao Z, Duncan GS, Chang CC, Elia A, Fang M, Wakeham A, Okada H, Calzascia T, Jang Y, You-Ten A, Yeh WC, Ohashi P, Wang X, Mak TW. Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis. Cell. 2005 May 20; 121(4):579-591. PMID: 15907471.
    Citations: 92     Fields:    Translation:AnimalsCells
  18. Benes CH, Wu N, Elia AE, Dharia T, Cantley LC, Soltoff SP. The C2 domain of PKCdelta is a phosphotyrosine binding domain. Cell. 2005 Apr 22; 121(2):271-80. PMID: 15851033.
    Citations: 125     Fields:    Translation:HumansAnimalsCells
  19. Manke IA, Nguyen A, Lim D, Stewart MQ, Elia AE, Yaffe MB. MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation. Mol Cell. 2005 Jan 07; 17(1):37-48. PMID: 15629715.
    Citations: 167     Fields:    Translation:HumansCells
  20. McPherson JP, Tamblyn L, Elia A, Migon E, Shehabeldin A, Matysiak-Zablocki E, Lemmers B, Salmena L, Hakem A, Fish J, Kassam F, Squire J, Bruneau BG, Hande MP, Hakem R. Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity. EMBO J. 2004 Sep 15; 23(18):3677-88. PMID: 15343267; PMCID: PMC517611.
    Citations: 80     Fields:    Translation:AnimalsCells
  21. Brown GE, Stewart MQ, Bissonnette SA, Elia AE, Wilker E, Yaffe MB. Distinct ligand-dependent roles for p38 MAPK in priming and activation of the neutrophil NADPH oxidase. J Biol Chem. 2004 Jun 25; 279(26):27059-68. PMID: 15102856.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  22. Cheung AM, Elia A, Tsao MS, Done S, Wagner KU, Hennighausen L, Hakem R, Mak TW. Brca2 deficiency does not impair mammary epithelium development but promotes mammary adenocarcinoma formation in p53(+/-) mutant mice. Cancer Res. 2004 Mar 15; 64(6):1959-65. PMID: 15026330.
    Citations: 20     Fields:    Translation:AnimalsCells
  23. Okada H, Bakal C, Shahinian A, Elia A, Wakeham A, Suh WK, Duncan GS, Ciofani M, Rottapel R, Zúñiga-Pflücker JC, Mak TW. Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death. J Exp Med. 2004 Feb 02; 199(3):399-410. PMID: 14757745; PMCID: PMC2211792.
    Citations: 59     Fields:    Translation:AnimalsCells
  24. Lowery DM, Mohammad DH, Elia AE, Yaffe MB. The Polo-box domain: a molecular integrator of mitotic kinase cascades and Polo-like kinase function. Cell Cycle. 2004 Feb; 3(2):128-31. PMID: 14712072.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  25. Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K, Mohammad D, Cantley LC, Smerdon SJ, Yaffe MB. The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell. 2003 Oct 03; 115(1):83-95. PMID: 14532005.
    Citations: 358     Fields:    Translation:HumansAnimalsCells
  26. Elia AE, Cantley LC, Yaffe MB. Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates. Science. 2003 Feb 21; 299(5610):1228-31. PMID: 12595692.
    Citations: 318     Fields:    Translation:HumansCells
  27. Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, Elia AE, Lu W, Brown EM, Quinn SJ, Ingber DE, Zhou J. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet. 2003 Feb; 33(2):129-37. PMID: 12514735.
    Citations: 831     Fields:    Translation:HumansAnimalsCells
  28. Yaffe MB, Elia AE. Phosphoserine/threonine-binding domains. Curr Opin Cell Biol. 2001 Apr; 13(2):131-8. PMID: 11248545.
    Citations: 101     Fields:    Translation:HumansAnimalsCells
  29. Ruland J, Duncan GS, Elia A, del Barco Barrantes I, Nguyen L, Plyte S, Millar DG, Bouchard D, Wakeham A, Ohashi PS, Mak TW. Bcl10 is a positive regulator of antigen receptor-induced activation of NF-kappaB and neural tube closure. Cell. 2001 Jan 12; 104(1):33-42. PMID: 11163238.
    Citations: 183     Fields:    Translation:AnimalsCells
  30. Liu X, Elia AE, Law SF, Golemis EA, Farley J, Wang T. A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1. EMBO J. 2000 Dec 15; 19(24):6759-69. PMID: 11118211; PMCID: PMC305889.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  31. Yoshida H, Kong YY, Yoshida R, Elia AJ, Hakem A, Hakem R, Penninger JM, Mak TW. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell. 1998 Sep 18; 94(6):739-50. PMID: 9753321.
    Citations: 281     Fields:    Translation:AnimalsCells
  32. Hakem R, Hakem A, Duncan GS, Henderson JT, Woo M, Soengas MS, Elia A, de la Pompa JL, Kagi D, Khoo W, Potter J, Yoshida R, Kaufman SA, Lowe SW, Penninger JM, Mak TW. Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell. 1998 Aug 07; 94(3):339-52. PMID: 9708736.
    Citations: 315     Fields:    Translation:AnimalsCells
  33. Sirard C, de la Pompa JL, Elia A, Itie A, Mirtsos C, Cheung A, Hahn S, Wakeham A, Schwartz L, Kern SE, Rossant J, Mak TW. The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo. Genes Dev. 1998 Jan 01; 12(1):107-19. PMID: 9420335; PMCID: PMC316400.
    Citations: 143     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.