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Benjamin Elison Gewurz, M.D.,Ph.D.

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Biography
awards and honors
2012 - 2017
Burroughs Wellcome Career Award in Medical Sciences
2012 - 2013
Fellow, Karin Grunebaum Cancer Research Foundation
2010
Maxwell Finland Award For Excellence in Research
2008
Scott James Thaler Award
2008
Brigham Research Institue (BRI) Research Excellence Award
2007 - 2010
Fellow, Leukemia & Lymphoma Society
2006
Edward Kass Award for Excellence in Clinical Medicine
2001
Jeffrey Modell Prize
2000
American Academy of Achievement Award
2000
Derek Bok Award for Excellence in Undergraduate Teaching
1997 - 2001
Howard Hughes Predoctoral Fellowship
1995
Phi Beta Kappa
1995
Firestone Medal for Excellence in Undergraduate Research
2019 - 2023
American Cancer Society Research Scholar Award
2018
Priscilla Schaffer Memorial Award
2019
Chair's Research Award
2020
Member, American Society of Clinical Investigation
2022
FASEB Keynote Lecture

Overview

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
  1. R01AI164709 (GEWURZ, BENJAMIN ELISON) Jul 6, 2021 - Jun 30, 2026
    NIH
    Regulation of the Epstein-Barr Virus Lytic Switch
    Role: Principal Investigator
  2. R01CA228700 (GEWURZ, BENJAMIN ELISON) Sep 19, 2019 - Aug 31, 2024
    NIH
    Epstein-Barr virus LMP1 mediated oncogenicity
    Role: Principal Investigator
  3. (Benjamin Gewurz) Jan 1, 2019 - Dec 31, 2022
    American Cancer Society
    Research Scholar Award
    Role: PI
  4. R01AI137337 (GEWURZ, BENJAMIN ELISON) Mar 15, 2018 - Feb 28, 2023
    NIH
    Metabolic Network Remodeling in Epstein-Barr Virus Lymphomagenesis
    Role: Principal Investigator
  5. (Benjamin Gewurz) Sep 1, 2012 - Jan 1, 2021
    Burroughs Wellcome Foundation Career Award in Medical Sciences
    Role Description: Career Award in Medical Sciences
    Role: PI

Featured Content
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Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Brownlie RJ, Kennedy R, Wilson EB, Milanovic M, Taylor CF, Wang D, Davies J, Owston HE, Adams EJ, Stephenson S, Caeser R, Gewurz BE, Giannoudis PV, Scuoppo C, McGonagle D, Hodson DJ, Tooze RM, Doody GM, Cook G, Westhead DR, Klein U. Cytokine receptor IL27RA is an NF-kB-responsive gene involved in CD38 upregulation in multiple myeloma. Blood Adv. 2023 Mar 03. PMID: 36867577.
    Citations:    Fields:    
  2. Burton EM, Gewurz BE. Correction: Epstein-Barr virus oncoprotein-driven B cell metabolism remodeling. PLoS Pathog. 2022 Oct; 18(10):e1010920. PMID: 36264852; PMCID: PMC9584359.
    Citations:    Fields:    
  3. Ding W, Wang C, Narita Y, Wang H, Leong MML, Huang A, Liao Y, Liu X, Okuno Y, Kimura H, Gewurz B, Teng M, Jin S, Sato Y, Zhao B. The Epstein-Barr Virus Enhancer Interaction Landscapes in Virus-Associated Cancer Cell Lines. J Virol. 2022 09 28; 96(18):e0073922. PMID: 36094314; PMCID: PMC9517713.
    Citations:    Fields:    Translation:HumansCells
  4. Guo R, Liang JH, Zhang Y, Lutchenkov M, Li Z, Wang Y, Trujillo-Alonso V, Puri R, Giulino-Roth L, Gewurz BE. Methionine metabolism controls the B cell EBV epigenome and viral latency. Cell Metab. 2022 09 06; 34(9):1280-1297.e9. PMID: 36070681; PMCID: PMC9482757.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  5. Guo R, Zhang Y, Teng M, Jiang C, Schineller M, Zhao B, Doench JG, O'Reilly RJ, Cesarman E, Giulino-Roth L, Gewurz BE. Author Correction: DNA methylation enzymes and PRC1 restrict B-cell Epstein-Barr virus oncoprotein expression. Nat Microbiol. 2022 Jun; 7(6):928. PMID: 35505195.
    Citations:    Fields:    
  6. Caruso LB, Guo R, Keith K, Madzo J, Maestri D, Boyle S, Wasserman J, Kossenkov A, Gewurz BE, Tempera I. The nuclear lamina binds the EBV genome during latency and regulates viral gene expression. PLoS Pathog. 2022 04; 18(4):e1010400. PMID: 35421198; PMCID: PMC9009669.
    Citations:    Fields:    Translation:HumansCells
  7. Burton EM, Voyer J, Gewurz BE. Epstein-Barr virus latency programs dynamically sensitize B cells to ferroptosis. Proc Natl Acad Sci U S A. 2022 03 15; 119(11):e2118300119. PMID: 35275790; PMCID: PMC8931387.
    Citations:    Fields:    Translation:HumansCells
  8. Yiu SPT, Guo R, Zerbe C, Weekes MP, Gewurz BE. Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments. Cell Rep. 2022 03 08; 38(10):110411. PMID: 35263599; PMCID: PMC8981113.
    Citations:    Fields:    Translation:HumansCells
  9. Burton EM, Gewurz BE. Epstein-Barr virus oncoprotein-driven B cell metabolism remodeling. PLoS Pathog. 2022 02; 18(2):e1010254. PMID: 35108325; PMCID: PMC8809547.
    Citations:    Fields:    Translation:HumansCells
  10. Guo R, Gewurz BE. Epigenetic control of the Epstein-Barr lifecycle. Curr Opin Virol. 2022 02; 52:78-88. PMID: 34891084; PMCID: PMC9112224.
    Citations: 3     Fields:    Translation:HumansCells
  11. Wang Z, Guo R, Trudeau SJ, Wolinsky E, Ast T, Liang JH, Jiang C, Ma Y, Teng M, Mootha VK, Gewurz BE. CYB561A3 is the key lysosomal iron reductase required for Burkitt B-cell growth and survival. Blood. 2021 12 02; 138(22):2216-2230. PMID: 34232987; PMCID: PMC8641094.
    Citations: 3     Fields:    Translation:HumansCells
  12. Liang JH, Wang C, Yiu SPT, Zhao B, Guo R, Gewurz BE. Epstein-Barr Virus Induced Cytidine Metabolism Roles in Transformed B-Cell Growth and Survival. mBio. 2021 08 31; 12(4):e0153021. PMID: 34281398.
    Citations: 4     Fields:    Translation:HumansCells
  13. Soldan SS, Anderson EM, Frase DM, Zhang Y, Caruso LB, Wang Y, Deakyne JS, Gewurz BE, Tempera I, Lieberman PM, Messick TE. EBNA1 inhibitors have potent and selective antitumor activity in xenograft models of Epstein-Barr virus-associated gastric cancer. Gastric Cancer. 2021 09; 24(5):1076-1088. PMID: 33929613; PMCID: PMC8338878.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  14. Farina A, Rosato E, York M, Gewurz BE, Trojanowska M, Farina GA. Innate Immune Modulation Induced by EBV Lytic Infection Promotes Endothelial Cell Inflammation and Vascular Injury in Scleroderma. Front Immunol. 2021; 12:651013. PMID: 33953718.
    Citations: 3     Fields:    Translation:HumansCells
  15. Zhang Y, Guo R, Kim SH, Shah H, Zhang S, Liang JH, Fang Y, Gentili M, Leary CNO, Elledge SJ, Hung DT, Mootha VK, Gewurz BE. SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication. Nat Commun. 2021 03 15; 12(1):1676. PMID: 33723254.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  16. Xia TL, Li X, Wang X, Zhu YJ, Zhang H, Cheng W, Chen ML, Ye Y, Li Y, Zhang A, Dai DL, Zhu QY, Yuan L, Zheng J, Huang H, Chen SQ, Xiao ZW, Wang HB, Roy G, Zhong Q, Lin D, Zeng YX, Wang J, Zhao B, Gewurz BE, Chen J, Zuo Z, Zeng MS. N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay. EMBO Rep. 2021 04 07; 22(4):e50128. PMID: 33605073.
    Citations: 13     Fields:    Translation:HumansCells
  17. Gu SS, Zhang W, Wang X, Jiang P, Traugh N, Li Z, Meyer C, Stewig B, Xie Y, Bu X, Manos MP, Font-Tello A, Gjini E, Lako A, Lim K, Conway J, Tewari AK, Zeng Z, Sahu AD, Tokheim C, Weirather JL, Fu J, Zhang Y, Kroger B, Liang JH, Cejas P, Freeman GJ, Rodig S, Long HW, Gewurz BE, Hodi FS, Brown M, Liu XS. Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade. Cancer Discov. 2021 06; 11(6):1524-1541. PMID: 33589424; PMCID: PMC8543117.
    Citations: 8     Fields:    Translation:Humans
  18. Zhang Y, Jiang C, Trudeau SJ, Narita Y, Zhao B, Teng M, Guo R, Gewurz BE. Histone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation. mBio. 2020 10 27; 11(5). PMID: 33109754.
    Citations: 9     Fields:    Translation:HumansCells
  19. Jin S, Li R, Chen MY, Yu C, Tang LQ, Liu YM, Li JP, Liu YN, Luo YL, Zhao Y, Zhang Y, Xia TL, Liu SX, Liu Q, Wang GN, You R, Peng JY, Li J, Han F, Wang J, Chen QY, Zhang L, Mai HQ, Gewurz BE, Zhao B, Young LS, Zhong Q, Bai F, Zeng MS. Single-cell transcriptomic analysis defines the interplay between tumor cells, viral infection, and the microenvironment in nasopharyngeal carcinoma. Cell Res. 2020 11; 30(11):950-965. PMID: 32901110; PMCID: PMC7784966.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  20. Dalton T, Doubrovina E, Pankov D, Reynolds R, Scholze H, Selvakumar A, Vizconde T, Savalia B, Dyomin V, Weigel C, Oakes CC, Alonso A, Elemento O, Pan H, Phillip JM, O'Reilly RJ, Gewurz BE, Cesarman E, Giulino-Roth L. Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy. Blood. 2020 05 21; 135(21):1870-1881. PMID: 32157281; PMCID: PMC7243148.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  21. Guo R, Zhang Y, Teng M, Jiang C, Schineller M, Zhao B, Doench JG, O'Reilly RJ, Cesarman E, Giulino-Roth L, Gewurz BE. DNA methylation enzymes and PRC1 restrict B-cell Epstein-Barr virus oncoprotein expression. Nat Microbiol. 2020 08; 5(8):1051-1063. PMID: 32424339; PMCID: PMC7462085.
    Citations: 11     Fields:    Translation:HumansCells
  22. Smith NA, Coleman CB, Gewurz BE, Rochford R. CD21 (Complement Receptor 2) Is the Receptor for Epstein-Barr Virus Entry into T Cells. J Virol. 2020 05 18; 94(11). PMID: 32238579.
    Citations: 17     Fields:    Translation:HumansCells
  23. Guo R, Jiang C, Zhang Y, Govande A, Trudeau SJ, Chen F, Fry CJ, Puri R, Wolinsky E, Schineller M, Frost TC, Gebre M, Zhao B, Giulino-Roth L, Doench JG, Teng M, Gewurz BE. MYC Controls the Epstein-Barr Virus Lytic Switch. Mol Cell. 2020 05 21; 78(4):653-669.e8. PMID: 32315601.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  24. Wang LW, Wang Z, Ersing I, Nobre L, Guo R, Jiang S, Trudeau S, Zhao B, Weekes MP, Gewurz BE. Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival. PLoS Pathog. 2019 09; 15(9):e1008030. PMID: 31518366.
    Citations: 19     Fields:    Translation:HumansCells
  25. Jiang C, Trudeau SJ, Cheong TC, Guo R, Teng M, Wang LW, Wang Z, Pighi C, Gautier-Courteille C, Ma Y, Jiang S, Wang C, Zhao B, Paillard L, Doench JG, Chiarle R, Gewurz BE. CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation. Cell Rep. 2019 07 30; 28(5):1307-1322.e8. PMID: 31365872; PMCID: PMC6684324.
    Citations: 4     Fields:    Translation:HumansCells
  26. Wang C, Jiang S, Zhang L, Li D, Liang J, Narita Y, Hou I, Zhong Q, Gewurz BE, Teng M, Zhao B. TAF Family Proteins and MEF2C Are Essential for Epstein-Barr Virus Super-Enhancer Activity. J Virol. 2019 08 15; 93(16). PMID: 31167905; PMCID: PMC6675876.
    Citations: 6     Fields:    Translation:HumansCells
  27. Wang LW, Shen H, Nobre L, Ersing I, Paulo JA, Trudeau S, Wang Z, Smith NA, Ma Y, Reinstadler B, Nomburg J, Sommermann T, Cahir-McFarland E, Gygi SP, Mootha VK, Weekes MP, Gewurz BE. Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation. Cell Metab. 2019 09 03; 30(3):539-555.e11. PMID: 31257153.
    Citations: 45     Fields:    Translation:HumansCells
  28. Wang C, Li D, Zhang L, Jiang S, Liang J, Narita Y, Hou I, Zhong Q, Zheng Z, Xiao H, Gewurz BE, Teng M, Zhao B. RNA Sequencing Analyses of Gene Expression during Epstein-Barr Virus Infection of Primary B Lymphocytes. J Virol. 2019 07 01; 93(13). PMID: 31019051; PMCID: PMC6580941.
    Citations: 25     Fields:    Translation:HumansCells
  29. Wang C, Jiang S, Ke L, Zhang L, Li D, Liang J, Narita Y, Hou I, Chen CH, Wang L, Zhong Q, Ling Y, Lv X, Xiang Y, Guo X, Teng M, Tsao SW, Gewurz BE, Zeng MS, Zhao B. Genome-wide CRISPR-based gene knockout screens reveal cellular factors and pathways essential for nasopharyngeal carcinoma. J Biol Chem. 2019 06 21; 294(25):9734-9745. PMID: 31073033; PMCID: PMC6597810.
    Citations: 2     Fields:    Translation:HumansCells
  30. Mitsialis V, Wu Y, Gewurz B, Bleday R, Doyle LA, Winter RW, Hamilton MJ. Raising the Barr: An Unexpected Lesion at Ileal-Cecal Resection. Dig Dis Sci. 2019 02; 64(2):353-357. PMID: 30535887.
    Citations:    Fields:    Translation:HumansCells
  31. Frost TC, Gewurz BE. Epigenetic crossroads of the Epstein-Barr virus B-cell relationship. Curr Opin Virol. 2018 10; 32:15-23. PMID: 30227386.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  32. Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX, Kieff E, Zhang Z, Gewurz BE, Zhao B, Zeng MS. Author Correction: Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry. Nat Microbiol. 2018 Sep; 3(9):1075. PMID: 29679064.
    Citations: 4     Fields:    
  33. Wang C, Zhou H, Xue Y, Liang J, Narita Y, Gerdt C, Zheng AY, Jiang R, Trudeau S, Peng CW, Gewurz BE, Zhao B. Epstein-Barr Virus Nuclear Antigen Leader Protein Coactivates EP300. J Virol. 2018 05 01; 92(9). PMID: 29467311; PMCID: PMC5899200.
    Citations: 5     Fields:    Translation:HumansCells
  34. Gebre M, Nomburg JL, Gewurz BE. CRISPR-Cas9 Genetic Analysis of Virus-Host Interactions. Viruses. 2018 01 30; 10(2). PMID: 29385696.
    Citations: 10     Fields:    Translation:HumansCells
  35. Jiang S, Wang LW, Walsh MJ, Trudeau SJ, Gerdt C, Zhao B, Gewurz BE. CRISPR/Cas9-Mediated Genome Editing in Epstein-Barr Virus-Transformed Lymphoblastoid B-Cell Lines. Curr Protoc Mol Biol. 2018 01 16; 121:31.12.1-31.12.23. PMID: 29337376.
    Citations: 10     Fields:    Translation:HumansCells
  36. Wang LW, Trudeau SJ, Wang C, Gerdt C, Jiang S, Zhao B, Gewurz BE. Modulating Gene Expression in Epstein-Barr Virus (EBV)-Positive B Cell Lines with CRISPRa and CRISPRi. Curr Protoc Mol Biol. 2018 01 16; 121:31.13.1-31.13.18. PMID: 29337370.
    Citations: 2     Fields:    Translation:HumansCells
  37. Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX, Kieff E, Zhang Z, Gewurz BE, Zhao B, Zeng MS. Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry. Nat Microbiol. 2018 02; 3(2):1-8. PMID: 29292383.
    Citations: 90     Fields:    Translation:HumansAnimalsCells
  38. Wang LW, Jiang S, Gewurz BE. Epstein-Barr Virus LMP1-Mediated Oncogenicity. J Virol. 2017 11 01; 91(21). PMID: 28835489; PMCID: PMC5640852.
    Citations: 52     Fields:    Translation:HumansAnimals
  39. Jiang S, Zhou H, Liang J, Gerdt C, Wang C, Ke L, Schmidt SCS, Narita Y, Ma Y, Wang S, Colson T, Gewurz B, Li G, Kieff E, Zhao B. The Epstein-Barr Virus Regulome in Lymphoblastoid Cells. Cell Host Microbe. 2017 Oct 11; 22(4):561-573.e4. PMID: 29024646; PMCID: PMC5662195.
    Citations: 47     Fields:    Translation:HumansCells
  40. Ersing I, Nobre L, Wang LW, Soday L, Ma Y, Paulo JA, Narita Y, Ashbaugh CW, Jiang C, Grayson NE, Kieff E, Gygi SP, Weekes MP, Gewurz BE. A Temporal Proteomic Map of Epstein-Barr Virus Lytic Replication in B Cells. Cell Rep. 2017 05 16; 19(7):1479-1493. PMID: 28514666.
    Citations: 37     Fields:    Translation:HumansCells
  41. Ma Y, Walsh MJ, Bernhardt K, Ashbaugh CW, Trudeau SJ, Ashbaugh IY, Jiang S, Jiang C, Zhao B, Root DE, Doench JG, Gewurz BE. CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors. Cell Host Microbe. 2017 May 10; 21(5):580-591.e7. PMID: 28494239; PMCID: PMC8938989.
    Citations: 64     Fields:    Translation:HumansCells
  42. Minamitani T, Ma Y, Zhou H, Kida H, Tsai CY, Obana M, Okuzaki D, Fujio Y, Kumanogoh A, Zhao B, Kikutani H, Kieff E, Gewurz BE, Yasui T. Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease. Proc Natl Acad Sci U S A. 2017 05 02; 114(18):4751-4756. PMID: 28351978; PMCID: PMC5422827.
    Citations: 22     Fields:    Translation:AnimalsCells
  43. Blondel CJ, Park JS, Hubbard TP, Pacheco AR, Kuehl CJ, Walsh MJ, Davis BM, Gewurz BE, Doench JG, Waldor MK. CRISPR/Cas9 Screens Reveal Requirements for Host Cell Sulfation and Fucosylation in Bacterial Type III Secretion System-Mediated Cytotoxicity. Cell Host Microbe. 2016 Aug 10; 20(2):226-37. PMID: 27453484; PMCID: PMC4982808.
    Citations: 32     Fields:    Translation:HumansCells
  44. Hunter JE, Butterworth JA, Zhao B, Sellier H, Campbell KJ, Thomas HD, Bacon CM, Cockell SJ, Gewurz BE, Perkins ND. The NF-?B subunit c-Rel regulates Bach2 tumour suppressor expression in B-cell lymphoma. Oncogene. 2016 06 30; 35(26):3476-84. PMID: 26522720; PMCID: PMC4853301.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  45. Minamitani T, Yasui T, Ma Y, Zhou H, Okuzaki D, Tsai CY, Sakakibara S, Gewurz BE, Kieff E, Kikutani H. Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A. Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37):11612-7. PMID: 26305967; PMCID: PMC4577157.
    Citations: 22     Fields:    Translation:AnimalsCells
  46. Greenfeld H, Takasaki K, Walsh MJ, Ersing I, Bernhardt K, Ma Y, Fu B, Ashbaugh CW, Cabo J, Mollo SB, Zhou H, Li S, Gewurz BE. TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog. 2015 May; 11(5):e1004890. PMID: 25996949.
    Citations: 38     Fields:    Translation:HumansCells
  47. Zhou H, Schmidt SC, Jiang S, Willox B, Bernhardt K, Liang J, Johannsen EC, Kharchenko P, Gewurz BE, Kieff E, Zhao B. Epstein-Barr virus oncoprotein super-enhancers control B cell growth. Cell Host Microbe. 2015 Feb 11; 17(2):205-16. PMID: 25639793; PMCID: PMC4539236.
    Citations: 83     Fields:    Translation:Cells
  48. Iannetti A, Ledoux AC, Tudhope SJ, Sellier H, Zhao B, Mowla S, Moore A, Hummerich H, Gewurz BE, Cockell SJ, Jat PS, Willmore E, Perkins ND. Regulation of p53 and Rb links the alternative NF-?B pathway to EZH2 expression and cell senescence. PLoS Genet. 2014 Sep; 10(9):e1004642. PMID: 25255445; PMCID: PMC4177746.
    Citations: 48     Fields:    Translation:HumansCells
  49. Zhao B, Barrera LA, Ersing I, Willox B, Schmidt SC, Greenfeld H, Zhou H, Mollo SB, Shi TT, Takasaki K, Jiang S, Cahir-McFarland E, Kellis M, Bulyk ML, Kieff E, Gewurz BE. The NF-?B genomic landscape in lymphoblastoid B cells. Cell Rep. 2014 Sep 11; 8(5):1595-606. PMID: 25159142.
    Citations: 87     Fields:    Translation:HumansCells
  50. Zhou X, Massol RH, Nakamura F, Chen X, Gewurz BE, Davis BM, Lencer WI, Waldor MK. Remodeling of the intestinal brush border underlies adhesion and virulence of an enteric pathogen. mBio. 2014 Aug 19; 5(4). PMID: 25139905.
    Citations: 17     Fields:    Translation:AnimalsCells
  51. Ersing I, Bernhardt K, Gewurz BE. NF-?B and IRF7 pathway activation by Epstein-Barr virus Latent Membrane Protein 1. Viruses. 2013 Jun 21; 5(6):1587-606. PMID: 23793113.
    Citations: 38     Fields:    Translation:HumansCells
  52. Zhou X, Gewurz BE, Ritchie JM, Takasaki K, Greenfeld H, Kieff E, Davis BM, Waldor MK. A Vibrio parahaemolyticus T3SS effector mediates pathogenesis by independently enabling intestinal colonization and inhibiting TAK1 activation. Cell Rep. 2013 May 30; 3(5):1690-702. PMID: 23623501.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  53. Gewurz BE, Towfic F, Mar JC, Shinners NP, Takasaki K, Zhao B, Cahir-McFarland ED, Quackenbush J, Xavier RJ, Kieff E. Genome-wide siRNA screen for mediators of NF-?B activation. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2467-72. PMID: 22308454.
    Citations: 58     Fields:    Translation:HumansCells
  54. Gewurz BE, Mar JC, Padi M, Zhao B, Shinners NP, Takasaki K, Bedoya E, Zou JY, Cahir-McFarland E, Quackenbush J, Kieff E. Canonical NF-kappaB activation is essential for Epstein-Barr virus latent membrane protein 1 TES2/CTAR2 gene regulation. J Virol. 2011 Jul; 85(13):6764-73. PMID: 21543491.
    Citations: 25     Fields:    Translation:HumansCells
  55. Zhao B, Mar JC, Maruo S, Lee S, Gewurz BE, Johannsen E, Holton K, Rubio R, Takada K, Quackenbush J, Kieff E. Epstein-Barr virus nuclear antigen 3C regulated genes in lymphoblastoid cell lines. Proc Natl Acad Sci U S A. 2011 Jan 04; 108(1):337-42. PMID: 21173222.
    Citations: 30     Fields:    Translation:HumansCells
  56. Boehm D, Gewurz BE, Kieff E, Cahir-McFarland E. Epstein-Barr latent membrane protein 1 transformation site 2 activates NF-kappaB in the absence of NF-kappaB essential modifier residues 133-224 or 373-419. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):18103-8. PMID: 20923877.
    Citations: 9     Fields:    Translation:HumansCells
  57. Song YJ, Izumi KM, Shinners NP, Gewurz BE, Kieff E. IRF7 activation by Epstein-Barr virus latent membrane protein 1 requires localization at activation sites and TRAF6, but not TRAF2 or TRAF3. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18448-53. PMID: 19017798.
    Citations: 24     Fields:    Translation:HumansCells
  58. Vannier E, Gewurz BE, Krause PJ. Human babesiosis. Infect Dis Clin North Am. 2008 Sep; 22(3):469-88, viii-ix. PMID: 18755385.
    Citations: 88     Fields:    Translation:HumansAnimalsPHPublic Health
  59. Gewurz BE, Marty FM, Baden LR, Katz JT. Human herpesvirus 6 encephalitis. Curr Infect Dis Rep. 2008 Jul; 10(4):292-9. PMID: 18765102.
    Citations: 9     
  60. Krause PJ, Gewurz BE, Hill D, Marty FM, Vannier E, Foppa IM, Furman RR, Neuhaus E, Skowron G, Gupta S, McCalla C, Pesanti EL, Young M, Heiman D, Hsue G, Gelfand JA, Wormser GP, Dickason J, Bia FJ, Hartman B, Telford SR, Christianson D, Dardick K, Coleman M, Girotto JE, Spielman A. Persistent and relapsing babesiosis in immunocompromised patients. Clin Infect Dis. 2008 Feb 01; 46(3):370-6. PMID: 18181735.
    Citations: 112     Fields:    Translation:HumansAnimals
  61. Gewurz BE, Harper JW. DNA-damage control: Claspin destruction turns off the checkpoint. Curr Biol. 2006 Nov 07; 16(21):R932-4. PMID: 17084694.
    Citations: 7     Fields:    Translation:AnimalsCells
  62. Gewurz BE, Dezube BJ, Pantanowitz L. HIV and the breast. AIDS Read. 2005 Aug; 15(8):392-6, 399-402. PMID: 16110554.
    Citations: 4     Fields:    Translation:Humans
  63. Gewurz BE, Jacobs M, Proper JA, Dahl TA, Fujiwara T, Dezube BJ. Capravirine, a nonnucleoside reverse-transcriptase inhibitor in patients infected with HIV-1: a phase 1 study. J Infect Dis. 2004 Dec 01; 190(11):1957-61. PMID: 15529260.
    Citations: 1     Fields:    Translation:HumansCellsCTClinical Trials
  64. Gewurz BE, Ploegh HL, Tortorella D. US2, a human cytomegalovirus-encoded type I membrane protein, contains a non-cleavable amino-terminal signal peptide. J Biol Chem. 2002 Mar 29; 277(13):11306-13. PMID: 11790769.
    Citations: 18     Fields:    Translation:HumansCells
  65. Gewurz BE, Gaudet R, Tortorella D, Wang EW, Ploegh HL. Virus subversion of immunity: a structural perspective. Curr Opin Immunol. 2001 Aug; 13(4):442-50. PMID: 11498300.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  66. Gewurz BE, Gaudet R, Tortorella D, Wang EW, Ploegh HL, Wiley DC. Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2. Proc Natl Acad Sci U S A. 2001 Jun 05; 98(12):6794-9. PMID: 11391001; PMCID: PMC34432.
    Citations: 59     Fields:    Translation:HumansCells
  67. Gewurz BE, Wang EW, Tortorella D, Schust DJ, Ploegh HL. Human cytomegalovirus US2 endoplasmic reticulum-lumenal domain dictates association with major histocompatibility complex class I in a locus-specific manner. J Virol. 2001 Jun; 75(11):5197-204. PMID: 11333901; PMCID: PMC114925.
    Citations: 39     Fields:    Translation:HumansCells
  68. McAdam AJ, Gewurz BE, Farkash EA, Sharpe AH. Either B7 costimulation or IL-2 can elicit generation of primary alloreactive CTL. J Immunol. 2000 Sep 15; 165(6):3088-93. PMID: 10975820.
    Citations: 6     Fields:    Translation:AnimalsCells
  69. Tortorella D, Gewurz B, Schust D, Furman M, Ploegh H. Down-regulation of MHC class I antigen presentation by HCMV; lessons for tumor immunology. Immunol Invest. 2000 May; 29(2):97-100. PMID: 10854174.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  70. McAdam AJ, Farkash EA, Gewurz BE, Sharpe AH. B7 costimulation is critical for antibody class switching and CD8(+) cytotoxic T-lymphocyte generation in the host response to vesicular stomatitis virus. J Virol. 2000 Jan; 74(1):203-8. PMID: 10590107; PMCID: PMC111529.
    Citations: 35     Fields:    Translation:AnimalsCells
  71. Tortorella D, Gewurz BE, Furman MH, Schust DJ, Ploegh HL. Viral subversion of the immune system. Annu Rev Immunol. 2000; 18:861-926. PMID: 10837078.
    Citations: 270     Fields:    Translation:HumansAnimalsCells
  72. Moxon ER, Gewurz BE, Richards JC, Inzana T, Jennings MP, Hood DW. Phenotypic switching of Haemophilus influenzae. Mol Microbiol. 1996 Mar; 19(5):1149-50. PMID: 8830271.
    Citations: 2     Fields:    Translation:Cells
  73. Ying SC, Marchalonis JJ, Gewurz AT, Siegel JN, Jiang H, Gewurz BE, Gewurz H. Reactivity of anti-human C-reactive protein (CRP) and serum amyloid P component (SAP) monoclonal antibodies with limulin and pentraxins of other species. Immunology. 1992 Jun; 76(2):324-30. PMID: 1378818.
    Citations: 4     Fields:    Translation:HumansAnimals
  74. Ying SC, Shephard E, de Beer FC, Siegel JN, Harris D, Gewurz BE, Fridkin M, Gewurz H. Localization of sequence-determined neoepitopes and neutrophil digestion fragments of C-reactive protein utilizing monoclonal antibodies and synthetic peptides. Mol Immunol. 1992 May; 29(5):677-87. PMID: 1374844.
    Citations: 12     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.