Harvard Catalyst Profiles

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Stephanie Mohr, PH.D.

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Research
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
Drosophila RNAi Screening Center (HMS) - Core services (6), Instruments (6), Plasmids (3875), RNAi libraries (12) and Resource Collection (1)
DF/HCC Collaborative Functional Genomics Core - Core services (8) and Instruments (4)
DNA Resource Core (DF/HCC) - Core services (7), Gene knockdown screening libraries (1), Instruments (7), Plasmids (2) and cDNA libraries (2)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mohr SE, Killilea DW. Editorial: Metal Biology Takes Flight: The Study of Metal Homeostasis and Detoxification in Insects. Front Genet. 2018; 9:221. PMID: 29971094.
    Citations:    
  2. Lee PT, Zirin J, Kanca O, Lin WW, Schulze KL, Li-Kroeger D, Tao R, Devereaux C, Hu Y, Chung V, Fang Y, He Y, Pan H, Ge M, Zuo Z, Housden BE, Mohr SE, Yamamoto S, Levis RW, Spradling AC, Perrimon N, Bellen HJ. A gene-specific T2A-GAL4 library for Drosophila. Elife. 2018 03 22; 7. PMID: 29565247.
    Citations: 1     Fields:    
  3. Mohr SE, Rudd K, Hu Y, Song WR, Gilly Q, Buckner M, Housden BE, Kelley C, Zirin J, Tao R, Amador G, Sierzputowska K, Comjean A, Perrimon N. Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila melanogaster Cultured Cells. G3 (Bethesda). 2018 02 02; 8(2):631-641. PMID: 29223976.
    Citations: 2     Fields:    Translation:AnimalsCells
  4. Hu Y, Vinayagam A, Nand A, Comjean A, Chung V, Hao T, Mohr SE, Perrimon N. Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data. Nucleic Acids Res. 2018 Jan 04; 46(D1):D567-D574. PMID: 29155944.
    Citations: 1     Fields:    
  5. Ewen-Campen B, Mohr SE, Hu Y, Perrimon N. Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity with CRISPR. Dev Cell. 2017 10 09; 43(1):6-9. PMID: 29017030.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  6. Ewen-Campen B, Yang-Zhou D, Fernandes VR, González DP, Liu LP, Tao R, Ren X, Sun J, Hu Y, Zirin J, Mohr SE, Ni JQ, Perrimon N. Optimized strategy for in vivo Cas9-activation in Drosophila. Proc Natl Acad Sci U S A. 2017 08 29; 114(35):9409-9414. PMID: 28808002.
    Citations: 4     Fields:    Translation:Animals
  7. Hu Y, Comjean A, Mohr SE, Perrimon N. Gene2Function: An Integrated Online Resource for Gene Function Discovery. G3 (Bethesda). 2017 08 07; 7(8):2855-2858. PMID: 28663344.
    Citations: 1     Fields:    
  8. Wang J, Al-Ouran R, Hu Y, Kim SY, Wan YW, Wangler MF, Yamamoto S, Chao HT, Comjean A, Mohr SE, Perrimon N, Liu Z, Bellen HJ. MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome. Am J Hum Genet. 2017 Jun 01; 100(6):843-853. PMID: 28502612.
    Citations: 10     Fields:    Translation:Humans
  9. Hu Y, Comjean A, Perrimon N, Mohr SE. The Drosophila Gene Expression Tool (DGET) for expression analyses. BMC Bioinformatics. 2017 Feb 10; 18(1):98. PMID: 28187709.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  10. Housden BE, Muhar M, Gemberling M, Gersbach CA, Stainier DY, Seydoux G, Mohr SE, Zuber J, Perrimon N. Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. Nat Rev Genet. 2017 01; 18(1):24-40. PMID: 27795562.
    Citations: 18     Fields:    Translation:HumansAnimals
  11. Hu Y, Comjean A, Roesel C, Vinayagam A, Flockhart I, Zirin J, Perkins L, Perrimon N, Mohr SE. FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update. Nucleic Acids Res. 2017 01 04; 45(D1):D672-D678. PMID: 27924039.
    Citations: 7     Fields:    Translation:Animals
  12. Vinayagam A, Kulkarni MM, Sopko R, Sun X, Hu Y, Nand A, Villalta C, Moghimi A, Yang X, Mohr SE, Hong P, Asara JM, Perrimon N. An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling. Cell Rep. 2016 09 13; 16(11):3062-3074. PMID: 27626673.
    Citations: 4     Fields:    Translation:AnimalsCells
  13. Mohr SE, Hu Y, Ewen-Campen B, Housden BE, Viswanatha R, Perrimon N. CRISPR guide RNA design for research applications. FEBS J. 2016 09; 283(17):3232-8. PMID: 27276584.
    Citations: 9     Fields:    Translation:HumansAnimals
  14. Housden BE, Valvezan AJ, Kelley C, Sopko R, Hu Y, Roesel C, Lin S, Buckner M, Tao R, Yilmazel B, Mohr SE, Manning BD, Perrimon N. Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi. Sci Signal. 2015 Sep 08; 8(393):rs9. PMID: 26350902.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  15. Perkins LA, Holderbaum L, Tao R, Hu Y, Sopko R, McCall K, Yang-Zhou D, Flockhart I, Binari R, Shim HS, Miller A, Housden A, Foos M, Randkelv S, Kelley C, Namgyal P, Villalta C, Liu LP, Jiang X, Huan-Huan Q, Wang X, Fujiyama A, Toyoda A, Ayers K, Blum A, Czech B, Neumuller R, Yan D, Cavallaro A, Hibbard K, Hall D, Cooley L, Hannon GJ, Lehmann R, Parks A, Mohr SE, Ueda R, Kondo S, Ni JQ, Perrimon N. The Transgenic RNAi Project at Harvard Medical School: Resources and Validation. Genetics. 2015 Nov; 201(3):843-52. PMID: 26320097.
    Citations: 48     Fields:    Translation:Animals
  16. Mohr SE, Hu Y, Rudd K, Buckner M, Gilly Q, Foster B, Sierzputowska K, Comjean A, Ye B, Perrimon N. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. G3 (Bethesda). 2015 Jul 21; 5(9):1919-24. PMID: 26199285.
    Citations: 3     Fields:    Translation:AnimalsCells
  17. Hu Y, Comjean A, Perkins LA, Perrimon N, Mohr SE. GLAD: an Online Database of Gene List Annotation for Drosophila. J Genomics. 2015; 3:75-81. PMID: 26157507.
    Citations: 7     
  18. Mohr SE, Smith JA, Shamu CE, Neumüller RA, Perrimon N. RNAi screening comes of age: improved techniques and complementary approaches. Nat Rev Mol Cell Biol. 2014 Sep; 15(9):591-600. PMID: 25145850.
    Citations: 86     Fields:    Translation:HumansAnimalsCells
  19. Yilmazel B, Hu Y, Sigoillot F, Smith JA, Shamu CE, Perrimon N, Mohr SE. Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis. BMC Bioinformatics. 2014 Jun 17; 15:192. PMID: 24934636.
    Citations: 15     Fields:    Translation:Animals
  20. Zhou R, Mohr S, Hannon GJ, Perrimon N. Inducing RNAi in Drosophila cells by soaking with dsRNA. Cold Spring Harb Protoc. 2014 May 01; 2014(5). PMID: 24786505.
    Citations: 2     Fields:    Translation:AnimalsCells
  21. Mohr SE, Hu Y, Kim K, Housden BE, Perrimon N. Resources for functional genomics studies in Drosophila melanogaster. Genetics. 2014 May; 197(1):1-18. PMID: 24653003.
    Citations: 18     Fields:    Translation:HumansAnimals
  22. Mohr SE. RNAi screening in Drosophila cells and in vivo. Methods. 2014 Jun 15; 68(1):82-8. PMID: 24576618.
    Citations: 12     Fields:    Translation:Animals
  23. Vinayagam A, Zirin J, Roesel C, Hu Y, Yilmazel B, Samsonova AA, Neumüller RA, Mohr SE, Perrimon N. Integrating protein-protein interaction networks with phenotypes reveals signs of interactions. Nat Methods. 2014 Jan; 11(1):94-9. PMID: 24240319.
    Citations: 36     Fields:    Translation:AnimalsCells
  24. Ren X, Sun J, Housden BE, Hu Y, Roesel C, Lin S, Liu LP, Yang Z, Mao D, Sun L, Wu Q, Ji JY, Xi J, Mohr SE, Xu J, Perrimon N, Ni JQ. Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):19012-7. PMID: 24191015.
    Citations: 95     Fields:    Translation:AnimalsCells
  25. Hu Y, Sopko R, Foos M, Kelley C, Flockhart I, Ammeux N, Wang X, Perkins L, Perrimon N, Mohr SE. FlyPrimerBank: an online database for Drosophila melanogaster gene expression analysis and knockdown evaluation of RNAi reagents. G3 (Bethesda). 2013 Sep 04; 3(9):1607-16. PMID: 23893746.
    Citations: 22     Fields:    Translation:Animals
  26. Hu Y, Roesel C, Flockhart I, Perkins L, Perrimon N, Mohr SE. UP-TORR: online tool for accurate and Up-to-Date annotation of RNAi Reagents. Genetics. 2013 Sep; 195(1):37-45. PMID: 23792952.
    Citations: 18     Fields:    Translation:Animals
  27. Zhou R, Mohr S, Hannon GJ, Perrimon N. Inducing RNAi in Drosophila cells by transfection with dsRNA. Cold Spring Harb Protoc. 2013 May 01; 2013(5):461-3. PMID: 23637371.
    Citations: 3     Fields:    Translation:AnimalsCells
  28. Bergwitz C, Wee MJ, Sinha S, Huang J, DeRobertis C, Mensah LB, Cohen J, Friedman A, Kulkarni M, Hu Y, Vinayagam A, Schnall-Levin M, Berger B, Perkins LA, Mohr SE, Perrimon N. Genetic determinants of phosphate response in Drosophila. PLoS One. 2013; 8(3):e56753. PMID: 23520455.
    Citations: 1     Fields:    Translation:AnimalsCells
  29. Vinayagam A, Hu Y, Kulkarni M, Roesel C, Sopko R, Mohr SE, Perrimon N. Protein complex-based analysis framework for high-throughput data sets. Sci Signal. 2013 Feb 26; 6(264):rs5. PMID: 23443684.
    Citations: 33     Fields:    Translation:HumansAnimals
  30. Neumüller RA, Wirtz-Peitz F, Lee S, Kwon Y, Buckner M, Hoskins RA, Venken KJ, Bellen HJ, Mohr SE, Perrimon N. Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. Genetics. 2012 Mar; 190(3):931-40. PMID: 22174071.
    Citations: 33     Fields:    Translation:AnimalsCells
  31. Flockhart IT, Booker M, Hu Y, McElvany B, Gilly Q, Mathey-Prevot B, Perrimon N, Mohr SE. FlyRNAi.org--the database of the Drosophila RNAi screening center: 2012 update. Nucleic Acids Res. 2012 Jan; 40(Database issue):D715-9. PMID: 22067456.
    Citations: 24     Fields:    Translation:Animals
  32. Mohr SE, Perrimon N. RNAi screening: new approaches, understandings, and organisms. Wiley Interdiscip Rev RNA. 2012 Mar-Apr; 3(2):145-58. PMID: 21953743.
    Citations: 43     Fields:    Translation:HumansAnimals
  33. Hu Y, Flockhart I, Vinayagam A, Bergwitz C, Berger B, Perrimon N, Mohr SE. An integrative approach to ortholog prediction for disease-focused and other functional studies. BMC Bioinformatics. 2011 Aug 31; 12:357. PMID: 21880147.
    Citations: 84     Fields:    Translation:HumansAnimals
  34. Booker M, Samsonova AA, Kwon Y, Flockhart I, Mohr SE, Perrimon N. False negative rates in Drosophila cell-based RNAi screens: a case study. BMC Genomics. 2011 Jan 20; 12:50. PMID: 21251254.
    Citations: 19     Fields:    Translation:AnimalsCells
  35. Markey AL, Mohr S, Day PJ. High-throughput droplet PCR. Methods. 2010 Apr; 50(4):277-81. PMID: 20117212.
    Citations: 4     Fields:    
  36. Mohr S, Bakal C, Perrimon N. Genomic screening with RNAi: results and challenges. Annu Rev Biochem. 2010; 79:37-64. PMID: 20367032.
    Citations: 106     Fields:    Translation:HumansAnimals
  37. Cormier CY, Mohr SE, Zuo D, Hu Y, Rolfs A, Kramer J, Taycher E, Kelley F, Fiacco M, Turnbull G, LaBaer J. Protein Structure Initiative Material Repository: an open shared public resource of structural genomics plasmids for the biological community. Nucleic Acids Res. 2010 Jan; 38(Database issue):D743-9. PMID: 19906724.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  38. Myrick KV, Huet F, Mohr SE, Alvarez-García I, Lu JT, Smith MA, Crosby MA, Gelbart WM. Large-scale functional annotation and expanded implementations of the P{wHy} hybrid transposon in the Drosophila melanogaster genome. Genetics. 2009 Jul; 182(3):653-60. PMID: 19398769.
    Citations: 2     Fields:    Translation:AnimalsCells
  39. Rolfs A, Montor WR, Yoon SS, Hu Y, Bhullar B, Kelley F, McCarron S, Jepson DA, Shen B, Taycher E, Mohr SE, Zuo D, Williamson J, Mekalanos J, Labaer J. Production and sequence validation of a complete full length ORF collection for the pathogenic bacterium Vibrio cholerae. Proc Natl Acad Sci U S A. 2008 Mar 18; 105(11):4364-9. PMID: 18337508.
    Citations: 15     Fields:    Translation:Cells
  40. Murthy T, Rolfs A, Hu Y, Shi Z, Raphael J, Moreira D, Kelley F, McCarron S, Jepson D, Taycher E, Zuo D, Mohr SE, Fernandez M, Brizuela L, LaBaer J. A full-genomic sequence-verified protein-coding gene collection for Francisella tularensis. PLoS One. 2007 Jun 27; 2(6):e577. PMID: 17593976.
    Citations: 16     Fields:    Translation:HumansCells
  41. Taycher E, Rolfs A, Hu Y, Zuo D, Mohr SE, Williamson J, Labaer J. A novel approach to sequence validating protein expression clones with automated decision making. BMC Bioinformatics. 2007 Jun 13; 8:198. PMID: 17567908.
    Citations: 6     Fields:    Translation:Cells
  42. Hu Y, Rolfs A, Bhullar B, Murthy TV, Zhu C, Berger MF, Camargo AA, Kelley F, McCarron S, Jepson D, Richardson A, Raphael J, Moreira D, Taycher E, Zuo D, Mohr S, Kane MF, Williamson J, Simpson A, Bulyk ML, Harlow E, Marsischky G, Kolodner RD, LaBaer J. Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. Genome Res. 2007 Apr; 17(4):536-43. PMID: 17322287.
    Citations: 55     Fields:    Translation:AnimalsCells
  43. Zuo D, Mohr SE, Hu Y, Taycher E, Rolfs A, Kramer J, Williamson J, LaBaer J. PlasmID: a centralized repository for plasmid clone information and distribution. Nucleic Acids Res. 2007 Jan; 35(Database issue):D680-4. PMID: 17132831.
    Citations: 13     Fields:    
  44. Mohr SE, Gelbart WM. Using the P[wHy] hybrid transposable element to disrupt genes in region 54D-55B in Drosophila melanogaster. Genetics. 2002 Sep; 162(1):165-76. PMID: 12242231.
    Citations: 9     Fields:    Translation:AnimalsCells
  45. Mohr SE, Boswell RE. Genetic analysis of Drosophila melanogaster polytene chromosome region 44D-45F: loci required for viability and fertility. Genetics. 2002 Apr; 160(4):1503-10. PMID: 11973305.
    Citations: 2     Fields:    Translation:Animals
  46. Mohr SE, Dillon ST, Boswell RE. The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis. Genes Dev. 2001 Nov 01; 15(21):2886-99. PMID: 11691839.
    Citations: 63     Fields:    Translation:AnimalsCells
  47. Curcio C, Baqui MM, Salvatore D, Rihn BH, Mohr S, Harney JW, Larsen PR, Bianco AC. The human type 2 iodothyronine deiodinase is a selenoprotein highly expressed in a mesothelioma cell line. J Biol Chem. 2001 Aug 10; 276(32):30183-7. PMID: 11425850.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  48. Mohr S, Wanner LA, Bertrand H, Lambowitz AM. Characterization of an unusual tRNA-like sequence found inserted in a Neurospora retroplasmid. Nucleic Acids Res. 2000 07 01; 28(13):1514-24. PMID: 11001704.
    Citations:    Fields:    Translation:AnimalsCells
  49. Mohr S, Wanner LA, Bertrand H, Lambowitz AM. Characterization of an unusual tRNA-like sequence found inserted in a Neurospora retroplasmid. Nucleic Acids Res. 2000 Apr 01; 28(7):1514-24. PMID: 10710417.
    Citations: 1     Fields:    Translation:AnimalsCells
  50. Mohr SE, Boswell RE. Zimp encodes a homologue of mouse Miz1 and PIAS3 and is an essential gene in Drosophila melanogaster. Gene. 1999 Mar 18; 229(1-2):109-16. PMID: 10095110.
    Citations: 13     Fields:    Translation:AnimalsCells
  51. Laser B, Mohr S, Odenbach W, Oettler G, Kück U. Parental and novel copies of the mitochondrial orf25 gene in the hybrid crop-plant triticale: predominant transcriptional expression of the maternal gene copy. Curr Genet. 1997 Nov; 32(5):337-47. PMID: 9371885.
    Citations: 8     Fields:    Translation:AnimalsCells
  52. Newmark PA, Mohr SE, Gong L, Boswell RE. mago nashi mediates the posterior follicle cell-to-oocyte signal to organize axis formation in Drosophila. Development. 1997 Aug; 124(16):3197-207. PMID: 9272960.
    Citations: 30     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.