Harvard Catalyst Profiles

Dr. James Sawalla Guseh is a cardiovascular physician-scientist at Massachusetts General Hospital.

Dr. Guseh completed his undergraduate study at Harvard College (2006, Cambridge, MA) and obtained his medical doctorate (M.D.) from Harvard Medical School (2011). He would complete his Internal Medicine Residency (2014) and Chief Residency (2016 - 2017) at Massachusetts General Hospital and completed his Cardiology and Sports Cardiology training (2019) at Massachusetts General Hospital.

He is a faculty member of the Cardiology Division at Mass General and Harvard Medical School and he is a faculty member of the MGH Cardiovascular Performance Program. His clinical interests focus on the cardiovascular care of competitive and recreational athletes. Dr. Guseh has a fundamental and translational interest in the adaptive molecular mechanisms underlying cardiac remodeling and exercise-induced cardioprotection. Using proteomic and sequencing-based approaches, he investigates how beneficial adaptations from exercise might be therapeutically applied to disease states like heart failure.

Honors and awards include the Roman W. DeSanctis Clinical Scholar Award (2015), the American Heart Association Laennec Young Clinician Award (2018), and the Harvard Medical School John S. LaDue Memorial Fellowship (2018 - 2019). He is the inaugural Frisbie Family Scholar and his work is currently funded by the American Heart Association, the Harold Amos Medical Faculty Development Program and the MGH Physician-Scientist Development Program.