Harvard Catalyst Profiles

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Shingo Kajimura, Ph.D.

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Mentoring
Available: 11/12/20, Expires: 10/31/25

Eukaryotic cells store metabolites in different organelles, a.k.a., subcellular metabolite compartmentalization. Distinct pools of metabolic enzymes and substrates provide another layer of flexibility in metabolite utilization, thereby allowing for robust adaptation to a variety of intrinsic and external changes. In turn, defects in the processes are associated with metabolic disorders, neurological diseases, aging, and cancer.

Our lab aims to uncover the regulatory mechanisms of subcellular metabolite fate with an emphasis on characterizing unknown mitochondrial metabolite transporters. Our lab is located at the Center for Life Sciences (CLS730) in the Division of Endocrinology, Diabetes & Metabolism, BIDMC. http://www.kajimuralab.org/


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK125283 (KAJIMURA, SHINGO) Dec 15, 2020 - Nov 30, 2025
    NIH
    Mitochondrial BCAA transporter in physiology and disease
    Role: Principal Investigator
  2. R01DK127575 (KAJIMURA, SHINGO) Sep 14, 2020 - Jun 30, 2025
    NIH
    Post-translational control of adipose tissue remodeling and metabolic health
    Role: Principal Investigator
  3. DP1DK126160 (KAJIMURA, SHINGO) Aug 1, 2020 - Jun 30, 2025
    NIH
    Mitochondrial metabolite compartmentalization in health and disease
    Role: Principal Investigator
  4. R01DK125281 (KAJIMURA, SHINGO) Jul 20, 2020 - Jun 30, 2024
    NIH
    Molecular control of beige fat heterogeneity
    Role: Principal Investigator
  5. R01DK112268 (KAJIMURA, SHINGO) Sep 20, 2016 - Jun 30, 2019
    NIH
    Biological roles and developmental pathway of burn-induced beige fat in humans
    Role: Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.