Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Collin Melveton Stultz, M.D.,Ph.D.

Title
Institution
Department
Address
Phone
Fax

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R13AR064585 (STULTZ, COLLIN M) May 16, 2013 - Apr 30, 2014
    NIH/NIAMS
    2013 Collagen Gordon Research Conference and Gordon Research Seminar
    Role: Principal Investigator
  2. R21NS063185 (STULTZ, COLLIN M) May 15, 2009 - Apr 30, 2012
    NIH/NINDS
    Structure-based Ligand Design of Inhibitors that Prevent Tau Aggregation
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Myers PD, Ng K, Severson K, Kartoun U, Dai W, Huang W, Anderson FA, Stultz CM. Identifying unreliable predictions in clinical risk models. NPJ Digit Med. 2020; 3:8. PMID: 31993506.
    Citations:    
  2. Myers PD, Huang W, Anderson F, Stultz CM. Choosing Clinical Variables for Risk Stratification Post-Acute Coronary Syndrome. Sci Rep. 2019 10 10; 9(1):14631. PMID: 31601916.
    Citations:    
  3. Bowman SEJ, Backman LRF, Bjork RE, Andorfer MC, Yori S, Caruso A, Stultz CM, Drennan CL. Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme. J Biol Inorg Chem. 2019 09; 24(6):817-829. PMID: 31250200.
    Citations:    
  4. Stultz CM. The Advent of Clinically Useful Deep Learning. JACC Clin Electrophysiol. 2019 05; 5(5):587-589. PMID: 31122380.
    Citations:    
  5. Myers PD, Scirica BM, Stultz CM. Machine Learning Improves Risk Stratification After Acute Coronary Syndrome. Sci Rep. 2017 10 04; 7(1):12692. PMID: 28978948.
    Citations:    Fields:    
  6. Burger VM, Vandervelde A, Hendrix J, Konijnenberg A, Sobott F, Loris R, Stultz CM. Hidden States within Disordered Regions of the CcdA Antitoxin Protein. J Am Chem Soc. 2017 02 22; 139(7):2693-2701. PMID: 28124913.
    Citations: 1     Fields:    Translation:Cells
  7. Liu Y, Scirica BM, Stultz CM, Guttag JV. Beatquency domain and machine learning improve prediction of cardiovascular death after acute coronary syndrome. Sci Rep. 2016 10 06; 6:34540. PMID: 27708350.
    Citations: 1     Fields:    Translation:Humans
  8. Burger VM, Arenas DJ, Stultz CM. A Structure-free Method for Quantifying Conformational Flexibility in proteins. Sci Rep. 2016 06 30; 6:29040. PMID: 27358108.
    Citations: 1     Fields:    Translation:Cells
  9. Ziegler Z, Schmidt M, Gurry T, Burger V, Stultz CM. Mollack: a web server for the automated creation of conformational ensembles for intrinsically disordered proteins. Bioinformatics. 2016 08 15; 32(16):2545-7. PMID: 27153636.
    Citations:    Fields:    Translation:Cells
  10. Burger VM, Nolasco DO, Stultz CM. Expanding the Range of Protein Function at the Far End of the Order-Structure Continuum. J Biol Chem. 2016 Mar 25; 291(13):6706-13. PMID: 26851282.
    Citations: 5     Fields:    Translation:HumansCells
  11. Gurry T, Fisher CK, Schmidt M, Stultz CM. Analyzing Ensembles of Amyloid Proteins Using Bayesian Statistics. Methods Mol Biol. 2016; 1345:269-80. PMID: 26453218.
    Citations:    Fields:    Translation:HumansCells
  12. DaSilva LC, Gurry T, Stultz CM. Toward a consensus in protein structure nomenclature. Intrinsically Disord Proteins. 2014; 2(1):e970902. PMID: 28232882.
    Citations:    
  13. Gurry T, Stultz CM. Mechanism of amyloid-ß fibril elongation. Biochemistry. 2014 Nov 11; 53(44):6981-91. PMID: 25330398.
    Citations: 7     Fields:    Translation:HumansCells
  14. Zhong C, Gurry T, Cheng AA, Downey J, Deng Z, Stultz CM, Lu TK. Strong underwater adhesives made by self-assembling multi-protein nanofibres. Nat Nanotechnol. 2014 Oct; 9(10):858-66. PMID: 25240674.
    Citations: 23     Fields:    Translation:AnimalsCells
  15. Liu Y, Syed Z, Scirica BM, Morrow DA, Guttag JV, Stultz CM. ECG morphological variability in beat space for risk stratification after acute coronary syndrome. J Am Heart Assoc. 2014 Jun 24; 3(3):e000981. PMID: 24963105.
    Citations: 4     Fields:    Translation:Humans
  16. Gee EP, Yüksel D, Stultz CM, Ingber DE. SLLISWD sequence in the 10FNIII domain initiates fibronectin fibrillogenesis. J Biol Chem. 2013 Jul 19; 288(29):21329-40. PMID: 23740248.
    Citations: 8     Fields:    Translation:HumansCells
  17. Fisher CK, Ullman O, Stultz CM. Comparative studies of disordered proteins with similar sequences: application to Aß40 and Aß42. Biophys J. 2013 Apr 02; 104(7):1546-55. PMID: 23561531.
    Citations: 4     Fields:    Translation:Cells
  18. Gurry T, Ullman O, Fisher CK, Perovic I, Pochapsky T, Stultz CM. The dynamic structure of a-synuclein multimers. J Am Chem Soc. 2013 Mar 13; 135(10):3865-72. PMID: 23398399.
    Citations: 23     Fields:    Translation:Cells
  19. Lu KG, Stultz CM. Insight into the degradation of type-I collagen fibrils by MMP-8. J Mol Biol. 2013 May 27; 425(10):1815-25. PMID: 23399546.
    Citations: 13     Fields:    Translation:AnimalsCells
  20. Liu JS, Schubert CR, Fu X, Fourniol FJ, Jaiswal JK, Houdusse A, Stultz CM, Moores CA, Walsh CA. Molecular basis for specific regulation of neuronal kinesin-3 motors by doublecortin family proteins. Mol Cell. 2012 Sep 14; 47(5):707-21. PMID: 22857951.
    Citations: 29     Fields:    Translation:AnimalsCells
  21. Walker S, Ullman O, Stultz CM. Using intramolecular disulfide bonds in tau protein to deduce structural features of aggregation-resistant conformations. J Biol Chem. 2012 Mar 16; 287(12):9591-600. PMID: 22291015.
    Citations: 7     Fields:    Translation:HumansCells
  22. Fisher CK, Ullman O, Stultz CM. Efficient construction of disordered protein ensembles in a Bayesian framework with optimal selection of conformations. Pac Symp Biocomput. 2012; 82-93. PMID: 22174265.
    Citations: 4     Fields:    Translation:HumansCells
  23. Ullman O, Fisher CK, Stultz CM. Explaining the structural plasticity of a-synuclein. J Am Chem Soc. 2011 Dec 07; 133(48):19536-46. PMID: 22029383.
    Citations: 31     Fields:    Translation:HumansCells
  24. Syed Z, Stultz CM, Scirica BM, Guttag JV. Computationally generated cardiac biomarkers for risk stratification after acute coronary syndrome. Sci Transl Med. 2011 Sep 28; 3(102):102ra95. PMID: 21957173.
    Citations: 5     Fields:    Translation:Humans
  25. Fisher CK, Stultz CM. Protein structure along the order-disorder continuum. J Am Chem Soc. 2011 Jul 06; 133(26):10022-5. PMID: 21650183.
    Citations: 10     Fields:    Translation:HumansCells
  26. Fisher CK, Stultz CM. Constructing ensembles for intrinsically disordered proteins. Curr Opin Struct Biol. 2011 Jun; 21(3):426-31. PMID: 21530234.
    Citations: 54     Fields:    Translation:Cells
  27. Chen MM, Bartlett AI, Nerenberg PS, Friel CT, Hackenberger CP, Stultz CM, Radford SE, Imperiali B. Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation. Proc Natl Acad Sci U S A. 2010 Dec 28; 107(52):22528-33. PMID: 21148421.
    Citations: 16     Fields:    Translation:Cells
  28. Fisher CK, Huang A, Stultz CM. Modeling intrinsically disordered proteins with bayesian statistics. J Am Chem Soc. 2010 Oct 27; 132(42):14919-27. PMID: 20925316.
    Citations: 38     Fields:    
  29. Phillips CM, Schreiter ER, Stultz CM, Drennan CL. Structural basis of low-affinity nickel binding to the nickel-responsive transcription factor NikR from Escherichia coli. Biochemistry. 2010 Sep 14; 49(36):7830-8. PMID: 20704276.
    Citations: 5     Fields:    Translation:Cells
  30. Phillips CM, Stultz CM, Drennan CL. Searching for the Nik operon: how a ligand-responsive transcription factor hunts for its DNA binding site. Biochemistry. 2010 Sep 14; 49(36):7757-63. PMID: 20712334.
    Citations: 1     Fields:    Translation:Cells
  31. Gurry T, Nerenberg PS, Stultz CM. The contribution of interchain salt bridges to triple-helical stability in collagen. Biophys J. 2010 Jun 02; 98(11):2634-43. PMID: 20513408.
    Citations: 7     Fields:    Translation:Cells
  32. Salsas-Escat R, Nerenberg PS, Stultz CM. Cleavage site specificity and conformational selection in type I collagen degradation. Biochemistry. 2010 May 18; 49(19):4147-58. PMID: 20394413.
    Citations: 13     Fields:    Translation:Cells
  33. Salsas-Escat R, Stultz CM. Conformational selection and collagenolysis in type III collagen. Proteins. 2010 Feb 01; 78(2):325-35. PMID: 19731369.
    Citations: 10     Fields:    Translation:HumansCells
  34. Syed Z, Stultz C, Kellis M, Indyk P, Guttag J. Motif Discovery in Physiological Datasets: A Methodology for Inferring Predictive Elements. ACM Trans Knowl Discov Data. 2010 Jan; 4(1):2. PMID: 20730037.
    Citations: 3     
  35. Phillips CM, Nerenberg PS, Drennan CL, Stultz CM. Physical basis of metal-binding specificity in Escherichia coli NikR. J Am Chem Soc. 2009 Jul 29; 131(29):10220-8. PMID: 19621966.
    Citations: 4     Fields:    Translation:Cells
  36. Schubert CR, Stultz CM. The multi-copy simultaneous search methodology: a fundamental tool for structure-based drug design. J Comput Aided Mol Des. 2009 Aug; 23(8):475-89. PMID: 19506805.
    Citations: 6     Fields:    Translation:HumansCells
  37. Huang A, Stultz CM. Finding order within disorder: elucidating the structure of proteins associated with neurodegenerative disease. Future Med Chem. 2009 Jun; 1(3):467-82. PMID: 21426127.
    Citations: 12     Fields:    Translation:HumansCells
  38. Syed Z, Sung P, Scirica BM, Morrow DA, Stultz CM, Guttag JV. Spectral energy of ECG morphologic differences to predict death. Cardiovasc Eng. 2009 Mar; 9(1):18-26. PMID: 19283476.
    Citations: 2     Fields:    Translation:Humans
  39. Yoon MK, Venkatachalam V, Huang A, Choi BS, Stultz CM, Chou JJ. Residual structure within the disordered C-terminal segment of p21(Waf1/Cip1/Sdi1) and its implications for molecular recognition. Protein Sci. 2009 Feb; 18(2):337-47. PMID: 19165719.
    Citations: 12     Fields:    Translation:HumansCells
  40. Syed Z, Scirica BM, Mohanavelu S, Sung P, Michelson EL, Cannon CP, Stone PH, Stultz CM, Guttag JV. Relation of death within 90 days of non-ST-elevation acute coronary syndromes to variability in electrocardiographic morphology. Am J Cardiol. 2009 Feb 01; 103(3):307-11. PMID: 19166680.
    Citations: 5     Fields:    Translation:Humans
  41. Huang A, Stultz CM. The effect of a DeltaK280 mutation on the unfolded state of a microtubule-binding repeat in Tau. PLoS Comput Biol. 2008 Aug 22; 4(8):e1000155. PMID: 18725924.
    Citations: 14     Fields:    Translation:HumansCells
  42. Nerenberg PS, Stultz CM. Differential unfolding of alpha1 and alpha2 chains in type I collagen and collagenolysis. J Mol Biol. 2008 Sep 26; 382(1):246-56. PMID: 18644377.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  43. Gee EP, Ingber DE, Stultz CM. Fibronectin unfolding revisited: modeling cell traction-mediated unfolding of the tenth type-III repeat. PLoS One. 2008; 3(6):e2373. PMID: 19020673.
    Citations: 26     Fields:    Translation:HumansCells
  44. Nerenberg PS, Salsas-Escat R, Stultz CM. Do collagenases unwind triple-helical collagen before peptide bond hydrolysis? Reinterpreting experimental observations with mathematical models. Proteins. 2008 Mar; 70(4):1154-61. PMID: 17932911.
    Citations: 15     Fields:    Translation:Cells
  45. Nerenberg PS, Salsas-Escat R, Stultz CM. Collagen--a necessary accomplice in the metastatic process. Cancer Genomics Proteomics. 2007 Sep-Oct; 4(5):319-28. PMID: 17993716.
    Citations: 8     Fields:    Translation:HumansAnimals
  46. Thomas AH, Edelman ER, Stultz CM. Collagen fragments modulate innate immunity. Exp Biol Med (Maywood). 2007 Mar; 232(3):406-11. PMID: 17327474.
    Citations: 11     Fields:    Translation:HumansCells
  47. Huang A, Stultz CM. Conformational sampling with implicit solvent models: application to the PHF6 peptide in tau protein. Biophys J. 2007 Jan 01; 92(1):34-45. PMID: 17040986.
    Citations: 6     Fields:    Translation:HumansCells
  48. Stultz CM. The folding mechanism of collagen-like model peptides explored through detailed molecular simulations. Protein Sci. 2006 Sep; 15(9):2166-77. PMID: 16943446.
    Citations: 4     Fields:    Translation:Cells
  49. Stultz CM. An Assessment of Potential of Mean Force Calculations with Implicit Solvent Models. J. Chem. Phys B. 2004; 108:16525-16532.
  50. Stultz CM, Edelman ER. A structural model that explains the effects of hyperglycemia on collagenolysis. Biophys J. 2003 Oct; 85(4):2198-204. PMID: 14507685.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  51. Stultz CM, Levin AD, Edelman ER. Phosphorylation-induced conformational changes in a mitogen-activated protein kinase substrate. Implications for tyrosine hydroxylase activation. J Biol Chem. 2002 Dec 06; 277(49):47653-61. PMID: 12361946.
    Citations: 8     Fields:    Translation:AnimalsCells
  52. Stultz CM. Localized unfolding of collagen explains collagenase cleavage near imino-poor sites. J Mol Biol. 2002 Jun 21; 319(5):997-1003. PMID: 12079342.
    Citations: 31     Fields:    Translation:HumansCells
  53. Stultz CM, Levin AD, Edelman ER. A Structural Model that Explains the Effects of Hyperglycemia on Collagenolysis. J. Biol. Chem. 2002; 277:47653-47661.
  54. Stultz CM, Karplus M. Dynamic ligand design and combinatorial optimization: designing inhibitors to endothiapepsin. Proteins. 2000 Aug 01; 40(2):258-89. PMID: 10842341.
    Citations: 9     Fields:    Translation:Cells
  55. Stultz CM, Karplus M. Dynamic Ligand Design and Combinatorial Optimization. Proteins, Structure Function and Genetics. 2000; 40:259-289.
  56. Stultz CM, Karplus M. MCSS functionality maps for a flexible protein. Proteins. 1999 Dec 01; 37(4):512-29. PMID: 10651268.
    Citations: 8     Fields:    Translation:Cells
  57. Stultz CM, Karplus M. MCSS Functionality Maps for a Flexible Protein. Proteins, Structure Function and Gentetics. 1999; 37:512-529.
  58. Stultz CM, Karplus M. On the Potential Surface of the Locally Enhanced Sampling Approximation. Journal of Chemical Physics. 1998; 109:8809-8815.
  59. Stultz CM. Studies in Structure Based Drug Design: Ligand Design with a Flexible Protein . 1997.
  60. Stultz CM, Nambudripad R, Lathrop R, White JV . Predicting Protein Structure with Probabilistic Models. Protein Structural Biology in Bio-Medical Research , Vol. 22B of Advances in Molecular and Cell Biology series editor: E. E. Bittar, Guest Editors: N.M. Allewell and C. Woodward. 1997; 447-506.
  61. Stultz CM. Predicting Protein Structure with Probabilistic Models. 1997.
  62. White JV, Stultz CM, Smith TF. Protein classification by stochastic modeling and optimal filtering of amino-acid sequences. Math Biosci. 1994 Jan; 119(1):35-75. PMID: 8111135.
    Citations: 34     Fields:    Translation:Cells
  63. Stultz CM, White JV, Smith TF. Structural analysis based on state-space modeling. Protein Sci. 1993 Mar; 2(3):305-14. PMID: 8453370.
    Citations: 41     Fields:    Translation:Cells
  64. Stultz CM, White JV, Smith TF. Structural Analysis Based on State Space Modeling. Protein Science. 1993; 2:305-314.
  65. Jacques HPJ, Morris C., Cho E., Stultz C., Yue J. , Laurencin C. Bioerodible Polymers: Novel Approaches for use in Bone. Polymer Preprints. 1990; 31:247.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Stultz's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (210)
Explore
_
Co-Authors (9)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.