Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Shaun Purcell, Ph.D.

Co-Author

This page shows the publications co-authored by Shaun Purcell and Steven McCarroll.
Connection Strength

2.063
  1. Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia. Nat Neurosci. 2016 11; 19(11):1433-1441.
    View in: PubMed
    Score: 0.175
  2. Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. N Engl J Med. 2014 Dec 25; 371(26):2477-87.
    View in: PubMed
    Score: 0.154
  3. No evidence for rare recessive and compound heterozygous disruptive variants in schizophrenia. Eur J Hum Genet. 2015 Apr; 23(4):555-7.
    View in: PubMed
    Score: 0.153
  4. A polygenic burden of rare disruptive mutations in schizophrenia. Nature. 2014 Feb 13; 506(7487):185-90.
    View in: PubMed
    Score: 0.145
  5. Discovery and statistical genotyping of copy-number variation from whole-exome sequencing depth. Am J Hum Genet. 2012 Oct 05; 91(4):597-607.
    View in: PubMed
    Score: 0.133
  6. Correction: Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Mol Psychiatry. 2021 Mar 05.
    View in: PubMed
    Score: 0.059
  7. Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Mol Psychiatry. 2021 Jan 22.
    View in: PubMed
    Score: 0.059
  8. Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry. Mol Psychiatry. 2020 10; 25(10):2455-2467.
    View in: PubMed
    Score: 0.054
  9. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nat Genet. 2019 05; 51(5):793-803.
    View in: PubMed
    Score: 0.052
  10. Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases. Biol Psychiatry. 2019 07 15; 86(2):110-119.
    View in: PubMed
    Score: 0.051
  11. Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. Transl Psychiatry. 2017 01 10; 7(1):e993.
    View in: PubMed
    Score: 0.045
  12. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nat Genet. 2017 01; 49(1):27-35.
    View in: PubMed
    Score: 0.044
  13. Ultra-rare disruptive and damaging mutations influence educational attainment in the general population. Nat Neurosci. 2016 12; 19(12):1563-1565.
    View in: PubMed
    Score: 0.044
  14. Analysis of protein-coding genetic variation in 60,706 humans. Nature. 2016 08 18; 536(7616):285-91.
    View in: PubMed
    Score: 0.043
  15. Functional analysis of rare variants found in schizophrenia implicates a critical role for GIT1-PAK3 signaling in neuroplasticity. Mol Psychiatry. 2017 03; 22(3):417-429.
    View in: PubMed
    Score: 0.043
  16. Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. Nat Neurosci. 2016 Apr; 19(4):571-7.
    View in: PubMed
    Score: 0.042
  17. Quantifying prion disease penetrance using large population control cohorts. Sci Transl Med. 2016 Jan 20; 8(322):322ra9.
    View in: PubMed
    Score: 0.042
  18. Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Mol Psychiatry. 2016 09; 21(9):1290-7.
    View in: PubMed
    Score: 0.041
  19. New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. Int J Epidemiol. 2015 Oct; 44(5):1706-21.
    View in: PubMed
    Score: 0.041
  20. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. Am J Hum Genet. 2015 Oct 01; 97(4):576-92.
    View in: PubMed
    Score: 0.041
  21. Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia. Transl Psychiatry. 2015 Jul 21; 5:e607.
    View in: PubMed
    Score: 0.040
  22. Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. Am J Hum Genet. 2014 Nov 06; 95(5):535-52.
    View in: PubMed
    Score: 0.038
  23. De novo CNVs in bipolar affective disorder and schizophrenia. Hum Mol Genet. 2014 Dec 15; 23(24):6677-83.
    View in: PubMed
    Score: 0.038
  24. Copy number variation in schizophrenia in Sweden. Mol Psychiatry. 2014 Jul; 19(7):762-73.
    View in: PubMed
    Score: 0.037
  25. De novo mutations in schizophrenia implicate synaptic networks. Nature. 2014 Feb 13; 506(7487):179-84.
    View in: PubMed
    Score: 0.036
  26. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet. 2013 Oct; 45(10):1150-9.
    View in: PubMed
    Score: 0.035
  27. Detecting large copy number variants using exome genotyping arrays in a large Swedish schizophrenia sample. Mol Psychiatry. 2013 Nov; 18(11):1178-84.
    View in: PubMed
    Score: 0.035
  28. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013 Sep; 45(9):984-94.
    View in: PubMed
    Score: 0.035
  29. The genomic psychiatry cohort: partners in discovery. Am J Med Genet B Neuropsychiatr Genet. 2013 Jun; 162B(4):306-12.
    View in: PubMed
    Score: 0.035
  30. zCall: a rare variant caller for array-based genotyping: genetics and population analysis. Bioinformatics. 2012 Oct 01; 28(19):2543-5.
    View in: PubMed
    Score: 0.033
  31. Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Mol Psychiatry. 2012 Sep; 17(9):880-6.
    View in: PubMed
    Score: 0.032
  32. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet. 2010 Nov; 42(11):949-60.
    View in: PubMed
    Score: 0.029
  33. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010 Nov; 42(11):937-48.
    View in: PubMed
    Score: 0.029
  34. Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function. PLoS Genet. 2010 Sep 09; 6(9):e1001097.
    View in: PubMed
    Score: 0.029
  35. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet. 2009 Mar; 41(3):334-41.
    View in: PubMed
    Score: 0.026
  36. Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nat Genet. 2008 Oct; 40(10):1253-60.
    View in: PubMed
    Score: 0.025
  37. A second generation human haplotype map of over 3.1 million SNPs. Nature. 2007 Oct 18; 449(7164):851-61.
    View in: PubMed
    Score: 0.024
  38. Genome-wide detection and characterization of positive selection in human populations. Nature. 2007 Oct 18; 449(7164):913-8.
    View in: PubMed
    Score: 0.024
  39. Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes. Diabetes. 2007 Mar; 56(3):685-93.
    View in: PubMed
    Score: 0.023
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.