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Purcell, Shaun
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Shaun Purcell, Ph.D.
Title
Associate Professor of Psychiatry
Institution
Brigham and Women's Hospital
Department
Psychiatry
Address
Brigham and Women's Hospital
Dept. of Psychiatry, Rm 394
221 Longwood Ave
Boston MA 02115
Phone
617/525-8039
Fax
617/726-8300
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webpage
|
research activities and funding
|
selected publications
|
Overview
webpage
Purcell lab
Luna (sleep EEG analysis software)
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
R01AG070867
(REDLINE, SUSAN S.)
May 1, 2021 - Feb 28, 2025
NIH
Longitudinal Relationships Among Sleep, Cognition and Alzheimer's Disease Biomarkers: Discerning Causal Associations, Mediators and Susceptibility
Role: Co-Principal Investigator
R21MD012738
(PURCELL, SHAUN M)
Sep 17, 2019 - Jun 30, 2021
NIH
Enhanced Measurement and Modeling of Sleep Electrophysiology to Better Understand Sleep Disparities
Role: Principal Investigator
R21HL145492
(PURCELL, SHAUN M)
Apr 1, 2019 - Mar 31, 2021
NIH
Sleep Physiology Dynamics: Quantification, Characterization and Genetic Dissection
Role: Principal Investigator
R01HL146339
(PURCELL, SHAUN M)
Jan 22, 2019 - Dec 31, 2021
NIH
Leveraging National Sleep Research Resource Data for Personalized Sleep Profiling
Role: Principal Investigator
R03MH108908
(PURCELL, SHAUN M)
Aug 15, 2016 - Jun 30, 2018
NIH
Genome-wide association study of sleep spindles and related polysomnography measures
Role: Principal Investigator
R01MH099126
(PURCELL, SHAUN M)
Sep 20, 2012 - Jul 31, 2016
NIH
Leveraging identity-by-descent information in large-scale population sequencing
Role: Principal Investigator
R01HG005827
(PURCELL, SHAUN M)
Sep 27, 2010 - Jun 30, 2019
NIH
Software for the analysis of large-scale genotyping and sequencing studies
Role: Principal Investigator
RC2MH089905
(PURCELL, SHAUN M)
Sep 30, 2009 - Aug 31, 2012
NIH
Whole genome sequencing of bipolar disorder and schizophrenia
Role: Principal Investigator
U01MH085513
(PURCELL, SHAUN M)
Sep 30, 2008 - Aug 31, 2010
NIH
4/5-The Psychiatric GWAS Consortium: Integrated &Coordinated GWAS Meta-Analyses
Role: Principal Investigator
R03MH073806
(PURCELL, SHAUN M)
Sep 1, 2006 - Aug 31, 2008
NIH
Gene-environment interaction in association analysis
Role: Principal Investigator
R01MH071681
(PURCELL, SHAUN M)
May 15, 2006 - Apr 30, 2012
NIH
Haplotype Mapping of Chromosome 5 Schizophrenia Locus
Role: Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Stokes PA, Rath P, Possidente T, He M,
Purcell S
,
Manoach DS
,
Stickgold R
,
Prerau MJ
. Transient oscillation dynamics during sleep provide a robust basis for electroencephalographic phenotyping and biomarker identification. Sleep. 2023 Jan 11; 46(1).
PMID:
36107467
; PMCID:
PMC9832519
.
Citations:
Fields:
Psy
Psychophysiology
Translation:
Humans
Liang J,
Wang H
,
Cade BE
, Kurniansyah N, He KY, Lee J,
Sands SA
, A Brody J, Chen H,
Gottlieb DJ
, Evans DS, Guo X, Gharib SA, Hale L, Hillman DR, Lutsey PL, Mukherjee S, Ochs-Balcom HM, Palmer LJ,
Purcell S
,
Saxena R
, Patel SR, Stone KL, Tranah GJ, Boerwinkle E, Lin X, Liu Y, Psaty BM, Vasan RS, Manichaikul A, Rich SS, Rotter JI,
Sofer T
,
Redline S
, Zhu X. Targeted Genome Sequencing Identifies Multiple Rare Variants in Caveolin-1 Associated with Obstructive Sleep Apnea. Am J Respir Crit Care Med. 2022 11 15; 206(10):1271-1280.
PMID:
35822943
; PMCID:
PMC9746833
.
Citations:
Fields:
Cri
Critical Care
Pul
Pulmonary Medicine
Kozhemiako N
, Mylonas D, Pan JQ,
Prerau MJ
,
Redline S
,
Purcell SM
. Sources of Variation in the Spectral Slope of the Sleep EEG. eNeuro. 2022 Sep-Oct; 9(5).
PMID:
36123117
; PMCID:
PMC9512622
.
Citations:
Fields:
Bra
Brain
Neu
Neurology
Translation:
Humans
Green SF, Frame T, Banerjee LV, Gimson A, Blackman J, Morrison H, Lloyd K, Rudd S, Frederick Fotherby WG, Bartsch U,
Purcell S
, Jones M, Coulthard L. A systematic review of the validity of non-invasive sleep-measuring devices in mid-to-late life adults: Future utility for Alzheimer's disease research. Sleep Med Rev. 2022 10; 65:101665.
PMID:
36208588
.
Citations:
Fields:
Neu
Neurology
Psy
Psychophysiology
Translation:
Humans
Xin Q,
Yuan RK
,
Zitting KM
, Wang W,
Purcell SM
, Vujovic N,
Ronda JM
,
Quan SF
,
Williams JS
, Buxton OM,
Duffy JF
,
Czeisler CA
. Impact of chronic sleep restriction on sleep continuity, sleep structure, and neurobehavioral performance. Sleep. 2022 07 11; 45(7).
PMID:
35218665
; PMCID:
PMC9272266
.
Citations:
Fields:
Psy
Psychophysiology
Translation:
Humans
CT
Clinical Trials
Mazzotti DR, Haendel MA, McMurry JA, Smith CJ, Buysse DJ, Roenneberg T, Penzel T,
Purcell S
,
Redline S
, Zhang Y, Merikangas KR, Menetski JP,
Mullington J
, Boudreau E. Sleep and circadian informatics data harmonization: a workshop report from the Sleep Research Society and Sleep Research Network. Sleep. 2022 06 13; 45(6).
PMID:
35030631
; PMCID:
PMC9189941
.
Citations:
Fields:
Psy
Psychophysiology
Translation:
Humans
Kozhemiako N
, Wang J, Jiang C, Wang LA, Gai G, Zou K, Wang Z, Yu X, Zhou L, Li S, Guo Z, Law R, Coleman J,
Mylonas D
, Shen L, Wang G, Tan S, Qin S, Huang H,
Murphy M
,
Stickgold R
,
Manoach D
, Zhou Z, Zhu W, Hal MH,
Purcell SM
, Pan JQ. Non-rapid eye movement sleep and wake neurophysiology in schizophrenia. Elife. 2022 05 17; 11.
PMID:
35578829
; PMCID:
PMC9113745
.
Citations:
Fields:
Bio
Biology
Translation:
Humans
Wang H
, Kurniansyah N,
Cade BE
,
Goodman MO
, Chen H,
Gottlieb DJ
, Gharib SA,
Purcell SM
,
Lin X
,
Saxena R
, Zhu X, Durda P, Tracy R, Liu Y, Taylor KD, Johnson WC, Gabriel S, Smith JD, Aguet F, Ardlie K, Blackwell T, Reiner AP, Rotter JI, Rich SS,
Redline S
,
Sofer T
. Upregulated heme biosynthesis increases obstructive sleep apnea severity: a pathway-based Mendelian randomization study. Sci Rep. 2022 01 27; 12(1):1472.
PMID:
35087136
; PMCID:
PMC8795126
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Cells
Jia X, Goes FS, Locke AE, Palmer D, Wang W, Cohen-Woods S, Genovese G, Jackson AU, Jiang C, Kvale M, Mullins N, Nguyen H, Pirooznia M, Rivera M, Ruderfer DM, Shen L, Thai K, Zawistowski M, Zhuang Y, Abecasis G, Akil H, Bergen S, Burmeister M, Chapman S, DelaBastide M, Juréus A, Kang HM, Kwok PY, Li JZ, Levy SE, Monson ET, Moran J, Sobell J, Watson S, Willour V, Zöllner S, Adolfsson R, Blackwood D, Boehnke M, Breen G, Corvin A, Craddock N, DiFlorio A, Hultman CM, Landen M, Lewis C,
McCarroll SA
, Richard McCombie W, McGuffin P, McIntosh A, McQuillin A, Morris D, Myers RM, O'Donovan M, Ophoff R, Boks M, Kahn R, Ouwehand W, Owen M, Pato C, Pato M, Posthuma D, Potash JB, Reif A, Sklar P,
Smoller J
, Sullivan PF, Vincent J, Walters J,
Neale B
,
Purcell S
, Risch N, Schaefer C, Stahl EA, Zandi PP, Scott LJ. Correction: Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Mol Psychiatry. 2021 Sep; 26(9):5251.
PMID:
33674754
; PMCID:
PMC9119210
.
Citations:
Fields:
Mol
Molecular Biology
Psy
Psychiatry
Cade BE
, Lee J,
Sofer T
,
Wang H
, Zhang M, Chen H, Gharib SA,
Gottlieb DJ
, Guo X, Lane JM, Liang J,
Lin X
, Mei H, Patel SR,
Purcell SM
,
Saxena R
, Shah NA, Evans DS, Hanis CL, Hillman DR, Mukherjee S, Palmer LJ, Stone KL, Tranah GJ, Abecasis GR, Boerwinkle EA, Correa A, Cupples LA, Kaplan RC, Nickerson DA, North KE, Psaty BM, Rotter JI, Rich SS, Tracy RP, Vasan RS, Wilson JG, Zhu X,
Redline S
. Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program. Genome Med. 2021 08 26; 13(1):136.
PMID:
34446064
; PMCID:
PMC8394596
.
Citations:
Fields:
Gen
Genetics
Translation:
Humans
Cells
Redline S
,
Purcell SM
. Sleep and Big Data: harnessing data, technology, and analytics for monitoring sleep and improving diagnostics, prediction, and interventions-an era for Sleep-Omics? Sleep. 2021 06 11; 44(6).
PMID:
33893509
; PMCID:
PMC8521745
.
Citations:
4
Fields:
Psy
Psychophysiology
Jia X, Goes FS, Locke AE, Palmer D, Wang W, Cohen-Woods S, Genovese G, Jackson AU, Jiang C, Kvale M, Mullins N, Nguyen H, Pirooznia M, Rivera M, Ruderfer DM, Shen L, Thai K, Zawistowski M, Zhuang Y, Abecasis G, Akil H, Bergen S, Burmeister M, Chapman S, DelaBastide M, Juréus A, Kang HM, Kwok PY, Li JZ, Levy SE, Monson ET, Moran J, Sobell J, Watson S, Willour V, Zöllner S, Adolfsson R, Blackwood D, Boehnke M, Breen G, Corvin A, Craddock N, DiFlorio A, Hultman CM, Landen M, Lewis C,
McCarroll SA
, Richard McCombie W, McGuffin P, McIntosh A, McQuillin A, Morris D, Myers RM, O'Donovan M, Ophoff R, Boks M, Kahn R, Ouwehand W, Owen M, Pato C, Pato M, Posthuma D, Potash JB, Reif A, Sklar P,
Smoller J
, Sullivan PF, Vincent J, Walters J,
Neale B
,
Purcell S
, Risch N, Schaefer C, Stahl EA, Zandi PP, Scott LJ. Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder. Mol Psychiatry. 2021 09; 26(9):5239-5250.
PMID:
33483695
; PMCID:
PMC8295400
.
Citations:
4
Fields:
Mol
Molecular Biology
Psy
Psychiatry
Translation:
Humans
Djonlagic I
, Mariani S, Fitzpatrick AL, Van Der Klei VMGTH, Johnson DA, Wood AC, Seeman T, Nguyen HT,
Prerau MJ
, Luchsinger JA, Dzierzewski JM, Rapp SR, Tranah GJ, Yaffe K,
Burdick KE
, Stone KL,
Redline S
,
Purcell SM
. Publisher Correction: Macro and micro sleep architecture and cognitive performance in older adults. Nat Hum Behav. 2021 Jan; 5(1):172-174.
PMID:
33328625
.
Citations:
1
Fields:
Beh
Behavioral Sciences
Psy
Psychology
Djonlagic I
, Mariani S, Fitzpatrick AL, Van Der Klei VMGTH, Johnson DA, Wood AC, Seeman T, Nguyen HT,
Prerau MJ
, Luchsinger JA, Dzierzewski JM, Rapp SR, Tranah GJ, Yaffe K,
Burdick KE
, Stone KL,
Redline S
,
Purcell SM
. Macro and micro sleep architecture and cognitive performance in older adults. Nat Hum Behav. 2021 01; 5(1):123-145.
PMID:
33199858
.
Citations:
17
Fields:
Beh
Behavioral Sciences
Psy
Psychology
Translation:
Humans
Nguyen TH, Dobbyn A, Brown RC, Riley BP, Buxbaum JD, Pinto D,
Purcell SM
, Sullivan PF, He X, Stahl EA. mTADA is a framework for identifying risk genes from de novo mutations in multiple traits. Nat Commun. 2020 06 10; 11(1):2929.
PMID:
32522981
.
Citations:
5
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Won CHJ, Reid M,
Sofer T
,
Azarbarzin A
,
Purcell S
, White D, Wellman A,
Sands S
,
Redline S
. Sex differences in obstructive sleep apnea phenotypes, the multi-ethnic study of atherosclerosis. Sleep. 2020 05 12; 43(5).
PMID:
31687772
.
Citations:
30
Fields:
Psy
Psychophysiology
Translation:
Humans
Sham PC,
Purcell SM
, Cherny SS, Neale MC,
Neale BM
. Statistical Power and the Classical Twin Design. Twin Res Hum Genet. 2020 04; 23(2):87-89.
PMID:
32638684
.
Citations:
1
Fields:
Gen
Genetics
Translation:
Humans
Smagula SF,
Sofer T
, Guo N,
Prerau M
,
Purcell S
, Mariani S, Yaffe K,
Redline S
, Stone KL. Spectral sleep electroencephalographic correlates of sleep efficiency, and discrepancies between actigraphy and self-reported measures, in older men. J Sleep Res. 2021 04; 30(2):e13033.
PMID:
32198950
; PMCID:
PMC7607534
.
Citations:
2