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Roberto Chiarle, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA222598 (CHIARLE, ROBERTO) Dec 18, 2017 - Nov 30, 2022
    NIH/NCI
    APOBEC proteins as drivers of chromosomal translocations in solid cancers
    Role: Principal Investigator
  2. R01CA196703 (CHIARLE, ROBERTO) Jul 16, 2015 - Jun 30, 2020
    NIH/NCI
    Mechanisms of resistance to ALK inhibitors in ALK-rearranged lymphoma
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jiang C, Trudeau SJ, Cheong TC, Guo R, Teng M, Wang LW, Wang Z, Pighi C, Gautier-Courteille C, Ma Y, Jiang S, Wang C, Zhao B, Paillard L, Doench JG, Chiarle R, Gewurz BE. CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation. Cell Rep. 2019 07 30; 28(5):1307-1322.e8. PMID: 31365872.
    Citations:    
  2. Voena C, Chiarle R. RHO Family GTPases in the Biology of Lymphoma. Cells. 2019 06 26; 8(7). PMID: 31248017.
    Citations:    
  3. Blasco RB, Patrucco E, Mota I, Tai WT, Chiarle R. Comment on "ALK is a therapeutic target for lethal sepsis". Sci Transl Med. 2018 12 12; 10(471). PMID: 30541790.
    Citations:    
  4. Menotti M, Ambrogio C, Cheong TC, Pighi C, Mota I, Cassel SH, Compagno M, Wang Q, Dall'Olio R, Minero VG, Poggio T, Sharma GG, Patrucco E, Mastini C, Choudhari R, Pich A, Zamo A, Piva R, Giliani S, Mologni L, Collings CK, Kadoch C, Gambacorti-Passerini C, Notarangelo LD, Anton IM, Voena C, Chiarle R. Wiskott-Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma. Nat Med. 2019 01; 25(1):130-140. PMID: 30510251.
    Citations:    Fields:    
  5. Layer JV, Cleary JP, Brown AJ, Stevenson KE, Morrow SN, Van Scoyk A, Blasco RB, Karaca E, Meng FL, Frock RL, Tivey T, Kim S, Fuchs H, Chiarle R, Alt FW, Roberts SA, Weinstock DM, Day TA. Parp3 promotes long-range end joining in murine cells. Proc Natl Acad Sci U S A. 2018 10 02; 115(40):10076-10081. PMID: 30213852.
    Citations:    Fields:    Translation:AnimalsCells
  6. Sharma GG, Mota I, Mologni L, Patrucco E, Gambacorti-Passerini C, Chiarle R. Tumor Resistance against ALK Targeted Therapy-Where It Comes From and Where It Goes. Cancers (Basel). 2018 Feb 28; 10(3). PMID: 29495603.
    Citations: 1     
  7. Ambrogio C, Köhler J, Zhou ZW, Wang H, Paranal R, Li J, Capelletti M, Caffarra C, Li S, Lv Q, Gondi S, Hunter JC, Lu J, Chiarle R, Santamaría D, Westover KD, Jänne PA. KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS. Cell. 2018 02 08; 172(4):857-868.e15. PMID: 29336889.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  8. Cheong TC, Blasco RB, Chiarle R. The CRISPR/Cas9 System as a Tool to Engineer Chromosomal Translocation In Vivo. Adv Exp Med Biol. 2018; 1044:39-48. PMID: 29956290.
    Citations:    Fields:    Translation:AnimalsCells
  9. Gulluni F, Martini M, De Santis MC, Campa CC, Ghigo A, Margaria JP, Ciraolo E, Franco I, Ala U, Annaratone L, Disalvatore D, Bertalot G, Viale G, Noatynska A, Compagno M, Sigismund S, Montemurro F, Thelen M, Fan F, Meraldi P, Marchiò C, Pece S, Sapino A, Chiarle R, Di Fiore PP, Hirsch E. Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2a Scaffolding Function. Cancer Cell. 2017 10 09; 32(4):444-459.e7. PMID: 29017056.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  10. Awad MM, Mastini C, Blasco RB, Mologni L, Voena C, Mussolin L, Mach SL, Adeni AE, Lydon CA, Sholl LM, Jänne PA, Chiarle R. Epitope mapping of spontaneous autoantibodies to anaplastic lymphoma kinase (ALK) in non-small cell lung cancer. Oncotarget. 2017 Nov 03; 8(54):92265-92274. PMID: 29190913.
    Citations: 3     Fields:    
  11. Platt CD, Fried AJ, Hoyos-Bachiloglu R, Usmani GN, Schmidt B, Whangbo J, Chiarle R, Chou J, Geha RS. Combined immunodeficiency with EBV positive B cell lymphoma and epidermodysplasia verruciformis due to a novel homozygous mutation in RASGRP1. Clin Immunol. 2017 10; 183:142-144. PMID: 28822832.
    Citations: 4     Fields:    Translation:HumansCells
  12. Nieto P, Ambrogio C, Esteban-Burgos L, Gómez-López G, Blasco MT, Yao Z, Marais R, Rosen N, Chiarle R, Pisano DG, Barbacid M, Santamaría D. A Braf kinase-inactive mutant induces lung adenocarcinoma. Nature. 2017 08 10; 548(7666):239-243. PMID: 28783725.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  13. Riccardo F, Réal A, Voena C, Chiarle R, Cavallo F, Barutello G. Maternal Immunization: New Perspectives on Its Application Against Non-Infectious Related Diseases in Newborns. Vaccines (Basel). 2017 Aug 01; 5(3). PMID: 28763018.
    Citations:    
  14. Fiorini C, Abdulhay NJ, McFarland SK, Munschauer M, Ulirsch JC, Chiarle R, Sankaran VG. Developmentally-faithful and effective human erythropoiesis in immunodeficient and Kit mutant mice. Am J Hematol. 2017 Sep; 92(9):E513-E519. PMID: 28568895.
    Citations: 1     Fields:    Translation:HumansAnimals
  15. Song H, Todd P, Chiarle R, Billett AL, Gellis S. Primary Cutaneous B-Cell Lymphoblastic Lymphoma Arising from a Long-Standing Lesion in a Child and Review of the Literature. Pediatr Dermatol. 2017 Jul; 34(4):e182-e186. PMID: 28547875.
    Citations:    Fields:    Translation:Humans
  16. Annaratone L, Simonetti M, Wernersson E, Marchiò C, Garnerone S, Scalzo MS, Bienko M, Chiarle R, Sapino A, Crosetto N. Quantification of HER2 and estrogen receptor heterogeneity in breast cancer by single-molecule RNA fluorescence in situ hybridization. Oncotarget. 2017 Mar 21; 8(12):18680-18698. PMID: 28423635.
    Citations: 1     Fields:    Translation:Humans
  17. Compagno M, Wang Q, Pighi C, Cheong TC, Meng FL, Poggio T, Yeap LS, Karaca E, Blasco RB, Langellotto F, Ambrogio C, Voena C, Wiestner A, Kasar SN, Brown JR, Sun J, Wu CJ, Gostissa M, Alt FW, Chiarle R. Phosphatidylinositol 3-kinase d blockade increases genomic instability in B cells. Nature. 2017 02 23; 542(7642):489-493. PMID: 28199309.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  18. Griggio V, Mandili G, Vitale C, Capello M, Macor P, Serra S, Castella B, Peola S, Foglietta M, Drandi D, Omedé P, Sblattero D, Cappello P, Chiarle R, Deaglio S, Boccadoro M, Novelli F, Massaia M, Coscia M. Humoral immune responses toward tumor-derived antigens in previously untreated patients with chronic lymphocytic leukemia. Oncotarget. 2017 Jan 10; 8(2):3274-3288. PMID: 27906678.
    Citations: 1     Fields:    Translation:HumansCells
  19. Guo MH, Nandakumar SK, Ulirsch JC, Zekavat SM, Buenrostro JD, Natarajan P, Salem RM, Chiarle R, Mitt M, Kals M, Pärn K, Fischer K, Milani L, Mägi R, Palta P, Gabriel SB, Metspalu A, Lander ES, Kathiresan S, Hirschhorn JN, Esko T, Sankaran VG. Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Proc Natl Acad Sci U S A. 2017 01 17; 114(3):E327-E336. PMID: 28031487.
    Citations: 10     Fields:    Translation:HumansCells
  20. Bersani F, Lingua MF, Morena D, Foglizzo V, Miretti S, Lanzetti L, Carrà G, Morotti A, Ala U, Provero P, Chiarle R, Singer S, Ladanyi M, Tuschl T, Ponzetto C, Taulli R. Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma. Cancer Res. 2016 10 15; 76(20):6095-6106. PMID: 27569217.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  21. Voena C, Varesio LM, Zhang L, Menotti M, Poggio T, Panizza E, Wang Q, Minero VG, Fagoonee S, Compagno M, Altruda F, Monti S, Chiarle R. Oncogenic ALK regulates EMT in non-small cell lung carcinoma through repression of the epithelial splicing regulatory protein 1. Oncotarget. 2016 May 31; 7(22):33316-30. PMID: 27119231.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  22. Morena D, Maestro N, Bersani F, Forni PE, Lingua MF, Foglizzo V, Šcepanovic P, Miretti S, Morotti A, Shern JF, Khan J, Ala U, Provero P, Sala V, Crepaldi T, Gasparini P, Casanova M, Ferrari A, Sozzi G, Chiarle R, Ponzetto C, Taulli R. Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes. Elife. 2016 Mar 17; 5. PMID: 26987019.
    Citations:    Fields:    Translation:HumansAnimals
  23. Cheong TC, Compagno M, Chiarle R. Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system. Nat Commun. 2016 Mar 09; 7:10934. PMID: 26956543.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  24. Voena C, Chiarle R. Advances in cancer immunology and cancer immunotherapy. Discov Med. 2016 Feb; 21(114):125-33. PMID: 27011048.
    Citations: 9     Fields:    Translation:HumansAnimals
  25. Choudhari R, Minero VG, Menotti M, Pulito R, Brakebusch C, Compagno M, Voena C, Ambrogio C, Chiarle R. Redundant and nonredundant roles for Cdc42 and Rac1 in lymphomas developed in NPM-ALK transgenic mice. Blood. 2016 Mar 10; 127(10):1297-306. PMID: 26747246.
    Citations: 4     Fields:    Translation:Animals
  26. Ceccon M, Merlo MEB, Mologni L, Poggio T, Varesio LM, Menotti M, Bombelli S, Rigolio R, Manazza AD, Di Giacomo F, Ambrogio C, Giudici G, Casati C, Mastini C, Compagno M, Turner SD, Gambacorti-Passerini C, Chiarle R, Voena C. Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency. Oncogene. 2016 07 21; 35(29):3854-3865. PMID: 26657151.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  27. Voena C, Menotti M, Mastini C, Di Giacomo F, Longo DL, Castella B, Merlo MEB, Ambrogio C, Wang Q, Minero VG, Poggio T, Martinengo C, D'Amico L, Panizza E, Mologni L, Cavallo F, Altruda F, Butaney M, Capelletti M, Inghirami G, Jänne PA, Chiarle R. Efficacy of a Cancer Vaccine against ALK-Rearranged Lung Tumors. Cancer Immunol Res. 2015 Dec; 3(12):1333-1343. PMID: 26419961.
    Citations: 9     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  28. Voena C, Peola S, Chiarle R. The anaplastic lymphoma kinase as an oncogene in solid tumors. Front Biosci (Schol Ed). 2015 Jun 01; 7:269-82. PMID: 25961702.
    Citations: 3     Fields:    Translation:HumansAnimals
  29. Karreth FA, Reschke M, Ruocco A, Ng C, Chapuy B, Léopold V, Sjoberg M, Keane TM, Verma A, Ala U, Tay Y, Wu D, Seitzer N, Velasco-Herrera Mdel C, Bothmer A, Fung J, Langellotto F, Rodig SJ, Elemento O, Shipp MA, Adams DJ, Chiarle R, Pandolfi PP. The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo. Cell. 2015 Apr 09; 161(2):319-32. PMID: 25843629.
    Citations: 60     Fields:    Translation:HumansAnimalsCells
  30. Alberti D, Protti N, Toppino A, Deagostino A, Lanzardo S, Bortolussi S, Altieri S, Voena C, Chiarle R, Geninatti Crich S, Aime S. A theranostic approach based on the use of a dual boron/Gd agent to improve the efficacy of Boron Neutron Capture Therapy in the lung cancer treatment. Nanomedicine. 2015 Apr; 11(3):741-50. PMID: 25596074.
    Citations: 4     Fields:    Translation:Animals
  31. Blasco RB, Karaca E, Ambrogio C, Cheong TC, Karayol E, Minero VG, Voena C, Chiarle R. Simple and rapid in vivo generation of chromosomal rearrangements using CRISPR/Cas9 technology. Cell Rep. 2014 Nov 20; 9(4):1219-27. PMID: 25456124.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  32. Barreca A, Martinengo C, Annaratone L, Righi L, Chiappella A, Ladetto M, Demurtas A, Chiusa L, Stacchini A, Crosetto N, van Oudenaarden A, Chiarle R. Inter- and intratumoral heterogeneity of BCL2 correlates with IgH expression and prognosis in follicular lymphoma. Blood Cancer J. 2014 Oct 10; 4:e249. PMID: 25303368.
    Citations: 6     Fields:    Translation:HumansCells
  33. Ambrogio C, Carmona FJ, Vidal A, Falcone M, Nieto P, Romero OA, Puertas S, Vizoso M, Nadal E, Poggio T, Sánchez-Céspedes M, Esteller M, Mulero F, Voena C, Chiarle R, Barbacid M, Santamaría D, Villanueva A. Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts. Cancer Res. 2014 Nov 01; 74(21):5978-88. PMID: 25217522.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  34. Marino F, Orecchia V, Regis G, Musteanu M, Tassone B, Jon C, Forni M, Calautti E, Chiarle R, Eferl R, Poli V. STAT3ß controls inflammatory responses and early tumor onset in skin and colon experimental cancer models. Am J Cancer Res. 2014; 4(5):484-94. PMID: 25232490.
    Citations: 3     
  35. Martinengo C, Poggio T, Menotti M, Scalzo MS, Mastini C, Ambrogio C, Pellegrino E, Riera L, Piva R, Ribatti D, Pastorino F, Perri P, Ponzoni M, Wang Q, Voena C, Chiarle R. ALK-dependent control of hypoxia-inducible factors mediates tumor growth and metastasis. Cancer Res. 2014 Nov 01; 74(21):6094-106. PMID: 25193384.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  36. Lattanzio R, La Sorda R, Facciolo F, Sioletic S, Lauriola L, Martucci R, Gallo E, Palmieri G, Evoli A, Alessandrini G, Ruco L, Rendina EA, Truini M, Chiarle R, Barreca A, Pich A, Ascani S, Remotti D, Tunesi G, Granone P, Ratto GB, Puma F, Pescarmona E, Piantelli M, Marino M, Carlini S, Cerasoli V, Corzani F, Melis E, Filippetti M, Canalini P, Palestro G, Lalle M, Ruffini E, Ceribelli A, Rinaldi M. Thymic epithelial tumors express vascular endothelial growth factors and their receptors as potential targets of antiangiogenic therapy: a tissue micro array-based multicenter study. Lung Cancer. 2014 Aug; 85(2):191-6. PMID: 24908332.
    Citations: 3     Fields:    Translation:Humans
  37. Gostissa M, Schwer B, Chang A, Dong J, Meyers RM, Marecki GT, Choi VW, Chiarle R, Zarrin AA, Alt FW. IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):2644-9. PMID: 24550291.
    Citations: 14     Fields:    Translation:Cells
  38. Semrau S, Crosetto N, Bienko M, Boni M, Bernasconi P, Chiarle R, van Oudenaarden A. FuseFISH: robust detection of transcribed gene fusions in single cells. Cell Rep. 2014 Jan 16; 6(1):18-23. PMID: 24373969.
    Citations: 15     Fields:    Translation:HumansCells
  39. Capello M, Cappello P, Linty FC, Chiarle R, Sperduti I, Novarino A, Salacone P, Mandili G, Naccarati A, Sacerdote C, Beghelli S, Bersani S, Barbi S, Bassi C, Scarpa A, Nisticò P, Giovarelli M, Vineis P, Milella M, Novelli F. Autoantibodies to Ezrin are an early sign of pancreatic cancer in humans and in genetically engineered mouse models. J Hematol Oncol. 2013 Sep 06; 6:67. PMID: 24010981.
    Citations: 7     Fields:    Translation:HumansAnimalsCTClinical Trials
  40. Piazza R, Magistroni V, Mogavero A, Andreoni F, Ambrogio C, Chiarle R, Mologni L, Bachmann PS, Lock RB, Collini P, Pelosi G, Gambacorti-Passerini C. Epigenetic silencing of the proapoptotic gene BIM in anaplastic large cell lymphoma through an MeCP2/SIN3a deacetylating complex. Neoplasia. 2013 May; 15(5):511-22. PMID: 23633923.
    Citations: 16     Fields:    Translation:HumansCells
  41. Voena C, Di Giacomo F, Panizza E, D'Amico L, Boccalatte FE, Pellegrino E, Todaro M, Recupero D, Tabbò F, Ambrogio C, Martinengo C, Bonello L, Pulito R, Hamm J, Chiarle R, Cheng M, Ruggeri B, Medico E, Inghirami G. The EGFR family members sustain the neoplastic phenotype of ALK+ lung adenocarcinoma via EGR1. Oncogenesis. 2013 Apr 08; 2:e43. PMID: 23567620.
    Citations: 12     
  42. Crosetto N, Mitra A, Silva MJ, Bienko M, Dojer N, Wang Q, Karaca E, Chiarle R, Skrzypczak M, Ginalski K, Pasero P, Rowicka M, Dikic I. Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing. Nat Methods. 2013 Apr; 10(4):361-5. PMID: 23503052.
    Citations: 77     Fields:    Translation:HumansAnimalsCells
  43. Camporeale A, Marino F, Papageorgiou A, Carai P, Fornero S, Fletcher S, Page BD, Gunning P, Forni M, Chiarle R, Morello M, Jensen O, Levi R, Heymans S, Poli V. STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy. EMBO Mol Med. 2013 Apr; 5(4):572-90. PMID: 23460527.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  44. Demurtas A, Stacchini A, Aliberti S, Chiusa L, Chiarle R, Novero D. Tissue flow cytometry immunophenotyping in the diagnosis and classification of non-Hodgkin's lymphomas: a retrospective evaluation of 1,792 cases. Cytometry B Clin Cytom. 2013 Mar; 84(2):82-95. PMID: 23325563.
    Citations: 2     Fields:    Translation:HumansCells
  45. Cappello P, Rolla S, Chiarle R, Principe M, Cavallo F, Perconti G, Feo S, Giovarelli M, Novelli F. Vaccination with ENO1 DNA prolongs survival of genetically engineered mice with pancreatic cancer. Gastroenterology. 2013 May; 144(5):1098-106. PMID: 23333712.
    Citations: 29     Fields:    Translation:AnimalsPHPublic Health
  46. Chiarle R. Translocations in normal B cells and cancers: insights from new technical approaches. Adv Immunol. 2013; 117:39-71. PMID: 23611285.
    Citations: 1     Fields:    Translation:HumansCells
  47. Voena C, Chiarle R. The battle against ALK resistance: successes and setbacks. Expert Opin Investig Drugs. 2012 Dec; 21(12):1751-4. PMID: 22920921.
    Citations: 8     Fields:    Translation:Humans
  48. Hirsch E, Chiarle R. Calming down T cell acute leukemia. Cancer Cell. 2012 Apr 17; 21(4):449-50. PMID: 22516253.
    Citations: 1     Fields:    
  49. Duan S, Cermak L, Pagan JK, Rossi M, Martinengo C, di Celle PF, Chapuy B, Shipp M, Chiarle R, Pagano M. FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas. Nature. 2012 Jan 05; 481(7379):90-3. PMID: 22113614.
    Citations: 80     Fields:    Translation:HumansAnimalsCells
  50. Chiarle R, Zhang Y, Frock RL, Lewis SM, Molinie B, Ho YJ, Myers DR, Choi VW, Compagno M, Malkin DJ, Neuberg D, Monti S, Giallourakis CC, Gostissa M, Alt FW. Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells. Cell. 2011 Sep 30; 147(1):107-19. PMID: 21962511.
    Citations: 159     Fields:    Translation:HumansAnimalsCells
  51. Di Paolo D, Ambrogio C, Pastorino F, Brignole C, Martinengo C, Carosio R, Loi M, Pagnan G, Emionite L, Cilli M, Ribatti D, Allen TM, Chiarle R, Ponzoni M, Perri P. Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma. Mol Ther. 2011 Dec; 19(12):2201-12. PMID: 21829174.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  52. Riera L, Lasorsa E, Bonello L, Sismondi F, Tondat F, Di Bello C, Di Celle PF, Chiarle R, Godio L, Pich A, Facchetti F, Ponzoni M, Marmont F, Zanon C, Bardelli A, Inghirami G. Description of a novel Janus kinase 3 P132A mutation in acute megakaryoblastic leukemia and demonstration of previously reported Janus kinase 3 mutations in normal subjects. Leuk Lymphoma. 2011 Sep; 52(9):1742-50. PMID: 21599579.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  53. Martinelli P, Bonetti P, Sironi C, Pruneri G, Fumagalli C, Raviele PR, Volorio S, Pileri S, Chiarle R, McDuff FK, Tusi BK, Turner SD, Inghirami G, Pelicci PG, Colombo E. The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway. Blood. 2011 Jun 16; 117(24):6617-26. PMID: 21518927.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  54. Di Paolo D, Brignole C, Pastorino F, Carosio R, Zorzoli A, Rossi M, Loi M, Pagnan G, Emionite L, Cilli M, Bruno S, Chiarle R, Allen TM, Ponzoni M, Perri P. Neuroblastoma-targeted nanoparticles entrapping siRNA specifically knockdown ALK. Mol Ther. 2011 Jun; 19(6):1131-40. PMID: 21487394.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  55. Gostissa M, Alt FW, Chiarle R. Mechanisms that promote and suppress chromosomal translocations in lymphocytes. Annu Rev Immunol. 2011; 29:319-50. PMID: 21219174.
    Citations: 60     Fields:    Translation:HumansAnimalsCells
  56. Bachetti T, Di Paolo D, Di Lascio S, Mirisola V, Brignole C, Bellotti M, Caffa I, Ferraris C, Fiore M, Fornasari D, Chiarle R, Borghini S, Pfeffer U, Ponzoni M, Ceccherini I, Perri P. PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma. PLoS One. 2010 Oct 01; 5(10). PMID: 20957039.
    Citations: 11     Fields:    Translation:HumansCells
  57. Boselli D, Ragimbeau J, Orlando L, Cappello P, Capello M, Ambrogio C, Chiarle R, Marsili G, Battistini A, Giovarelli M, Pellegrini S, Novelli F. Expression of IFN?R2 mutated in a dileucine internalization motif reinstates IFN? signaling and apoptosis in human T lymphocytes. Immunol Lett. 2010 Nov 30; 134(1):17-25. PMID: 20709103.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  58. Riera L, Lasorsa E, Ambrogio C, Surrenti N, Voena C, Chiarle R. Involvement of Grb2 adaptor protein in nucleophosmin-anaplastic lymphoma kinase (NPM-ALK)-mediated signaling and anaplastic large cell lymphoma growth. J Biol Chem. 2010 Aug 20; 285(34):26441-50. PMID: 20554525.
    Citations: 9     Fields:    Translation:HumansCells
  59. Barbieri I, Quaglino E, Maritano D, Pannellini T, Riera L, Cavallo F, Forni G, Musiani P, Chiarle R, Poli V. Stat3 is required for anchorage-independent growth and metastasis but not for mammary tumor development downstream of the ErbB-2 oncogene. Mol Carcinog. 2010 Feb; 49(2):114-20. PMID: 20027636.
    Citations: 14     Fields:    Translation:AnimalsCells
  60. Gonzalo P, Guadamillas MC, Hernández-Riquer MV, Pollán A, Grande-García A, Bartolomé RA, Vasanji A, Ambrogio C, Chiarle R, Teixidó J, Risteli J, Apte SS, del Pozo MA, Arroyo AG. MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling. Dev Cell. 2010 Jan 19; 18(1):77-89. PMID: 20152179.
    Citations: 35     Fields:    Translation:AnimalsCells
  61. Zhang Y, Gostissa M, Hildebrand DG, Becker MS, Boboila C, Chiarle R, Lewis S, Alt FW. The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers. Adv Immunol. 2010; 106:93-133. PMID: 20728025.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  62. Fornari A, Piva R, Chiarle R, Novero D, Inghirami G. Anaplastic large cell lymphoma: one or more entities among T-cell lymphoma? Hematol Oncol. 2009 Dec; 27(4):161-70. PMID: 19358142.
    Citations: 14     Fields:    Translation:Humans
  63. Ambrogio C, Martinengo C, Voena C, Tondat F, Riera L, di Celle PF, Inghirami G, Chiarle R. NPM-ALK oncogenic tyrosine kinase controls T-cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells. Cancer Res. 2009 Nov 15; 69(22):8611-9. PMID: 19887607.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  64. Carbone A, Vizio B, Novarino A, Mauri FA, Geuna M, Robino C, Brondino G, Prati A, Giacobino A, Campra D, Chiarle R, Fronda GR, Ciuffreda L, Bellone G. IL-18 paradox in pancreatic carcinoma: elevated serum levels of free IL-18 are correlated with poor survival. J Immunother. 2009 Nov-Dec; 32(9):920-31. PMID: 19816189.
    Citations: 6     Fields:    Translation:HumansCells
  65. Cappello P, Tomaino B, Chiarle R, Ceruti P, Novarino A, Castagnoli C, Migliorini P, Perconti G, Giallongo A, Milella M, Monsurrò V, Barbi S, Scarpa A, Nisticò P, Giovarelli M, Novelli F. An integrated humoral and cellular response is elicited in pancreatic cancer by alpha-enolase, a novel pancreatic ductal adenocarcinoma-associated antigen. Int J Cancer. 2009 Aug 01; 125(3):639-48. PMID: 19425054.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  66. Regis G, Icardi L, Conti L, Chiarle R, Piva R, Giovarelli M, Poli V, Novelli F. IL-6, but not IFN-gamma, triggers apoptosis and inhibits in vivo growth of human malignant T cells on STAT3 silencing. Leukemia. 2009 Nov; 23(11):2102-8. PMID: 19626047.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  67. Barberis L, Pasquali C, Bertschy-Meier D, Cuccurullo A, Costa C, Ambrogio C, Vilbois F, Chiarle R, Wymann M, Altruda F, Rommel C, Hirsch E. Leukocyte transmigration is modulated by chemokine-mediated PI3Kgamma-dependent phosphorylation of vimentin. Eur J Immunol. 2009 Apr; 39(4):1136-46. PMID: 19291697.
    Citations: 16     Fields:    Translation:AnimalsCells
  68. Mastini C, Martinengo C, Inghirami G, Chiarle R. Anaplastic lymphoma kinase: an oncogene for tumor vaccination. J Mol Med (Berl). 2009 Jul; 87(7):669-77. PMID: 19330473.
    Citations: 2     Fields:    Translation:HumansAnimals
  69. Ambrogio C, Voena C, Manazza AD, Martinengo C, Costa C, Kirchhausen T, Hirsch E, Inghirami G, Chiarle R. The anaplastic lymphoma kinase controls cell shape and growth of anaplastic large cell lymphoma through Cdc42 activation. Cancer Res. 2008 Nov 01; 68(21):8899-907. PMID: 18974134.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  70. Barutta F, Pinach S, Giunti S, Vittone F, Forbes JM, Chiarle R, Arnstein M, Perin PC, Camussi G, Cooper ME, Gruden G. Heat shock protein expression in diabetic nephropathy. Am J Physiol Renal Physiol. 2008 Dec; 295(6):F1817-24. PMID: 18922888.
    Citations: 9     Fields:    Translation:AnimalsCells
  71. Boccalatte FE, Voena C, Riganti C, Bosia A, D'Amico L, Riera L, Cheng M, Ruggeri B, Jensen ON, Goss VL, Lee K, Nardone J, Rush J, Polakiewicz RD, Comb MJ, Chiarle R, Inghirami G. The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL. Blood. 2009 Mar 19; 113(12):2776-90. PMID: 18845790.
    Citations: 19     Fields:    Translation:HumansCells
  72. Chiarle R, Martinengo C, Mastini C, Ambrogio C, D'Escamard V, Forni G, Inghirami G. The anaplastic lymphoma kinase is an effective oncoantigen for lymphoma vaccination. Nat Med. 2008 Jun; 14(6):676-80. PMID: 18469826.
    Citations: 33     Fields:    Translation:AnimalsCellsPHPublic Health
  73. Dewilde S, Vercelli A, Chiarle R, Poli V. Of alphas and betas: distinct and overlapping functions of STAT3 isoforms. Front Biosci. 2008 May 01; 13:6501-14. PMID: 18508676.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  74. Canaparo R, Serpe L, Zara GP, Chiarle R, Berta L, Frairia R. High energy shock waves (HESW) increase paclitaxel efficacy in a syngeneic model of breast cancer. Technol Cancer Res Treat. 2008 Apr; 7(2):117-24. PMID: 18345700.
    Citations: 1     Fields:    Translation:Animals
  75. Accornero P, Lattanzio G, Mangano T, Chiarle R, Taulli R, Bersani F, Forni PE, Miretti S, Scuoppo C, Dastrù W, Christensen JG, Crepaldi T, Ponzetto C. An in vivo model of Met-driven lymphoma as a tool to explore the therapeutic potential of Met inhibitors. Clin Cancer Res. 2008 Apr 01; 14(7):2220-6. PMID: 18381964.
    Citations: 7     Fields:    Translation:HumansAnimals
  76. Chiarle R, Voena C, Ambrogio C, Piva R, Inghirami G. The anaplastic lymphoma kinase in the pathogenesis of cancer. Nat Rev Cancer. 2008 Jan; 8(1):11-23. PMID: 18097461.
    Citations: 218     Fields:    Translation:Humans
  77. Tomaino B, Cappello P, Capello M, Fredolini C, Ponzetto A, Novarino A, Ciuffreda L, Bertetto O, De Angelis C, Gaia E, Salacone P, Milella M, Nisticò P, Alessio M, Chiarle R, Giuffrida MG, Giovarelli M, Novelli F. Autoantibody signature in human ductal pancreatic adenocarcinoma. J Proteome Res. 2007 Oct; 6(10):4025-31. PMID: 17824682.
    Citations: 19     Fields:    Translation:HumansCells
  78. Costa C, Barberis L, Ambrogio C, Manazza AD, Patrucco E, Azzolino O, Neilsen PO, Ciraolo E, Altruda F, Prestwich GD, Chiarle R, Wymann M, Ridley A, Hirsch E. Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14354-9. PMID: 17720808.
    Citations: 19     Fields:    Translation:AnimalsCells
  79. Scarpino S, Di Napoli A, Stoppacciaro A, Antonelli M, Pilozzi E, Chiarle R, Palestro G, Marino M, Facciolo F, Rendina EA, Webster KE, Kinkel SA, Scott HS, Ruco L. Expression of autoimmune regulator gene (AIRE) and T regulatory cells in human thymomas. Clin Exp Immunol. 2007 Sep; 149(3):504-12. PMID: 17590173.
    Citations: 15     Fields:    Translation:HumansCells
  80. Berto G, Camera P, Fusco C, Imarisio S, Ambrogio C, Chiarle R, Silengo L, Di Cunto F. The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase. J Cell Sci. 2007 Jun 01; 120(Pt 11):1859-67. PMID: 17488780.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  81. Voena C, Conte C, Ambrogio C, Boeri Erba E, Boccalatte F, Mohammed S, Jensen ON, Palestro G, Inghirami G, Chiarle R. The tyrosine phosphatase Shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migration. Cancer Res. 2007 May 01; 67(9):4278-86. PMID: 17483340.
    Citations: 27     Fields:    Translation:HumansCells
  82. Crepaldi T, Bersani F, Scuoppo C, Accornero P, Prunotto C, Taulli R, Forni PE, Leo C, Chiarle R, Griffiths J, Glass DJ, Ponzetto C. Conditional activation of MET in differentiated skeletal muscle induces atrophy. J Biol Chem. 2007 Mar 02; 282(9):6812-22. PMID: 17194700.
    Citations: 12     Fields:    Translation:AnimalsCells
  83. Conti L, Regis G, Longo A, Bernabei P, Chiarle R, Giovarelli M, Novelli F. In the absence of IGF-1 signaling, IFN-gamma suppresses human malignant T-cell growth. Blood. 2007 Mar 15; 109(6):2496-504. PMID: 17148586.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  84. Piva R, Pellegrino E, Mattioli M, Agnelli L, Lombardi L, Boccalatte F, Costa G, Ruggeri BA, Cheng M, Chiarle R, Palestro G, Neri A, Inghirami G. Functional validation of the anaplastic lymphoma kinase signature identifies CEBPB and BCL2A1 as critical target genes. J Clin Invest. 2006 Dec; 116(12):3171-82. PMID: 17111047.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  85. Robino C, Barilaro MR, Gino S, Chiarle R, Palestro G, Torre C. Incestuous paternity detected by STR-typing of chorionic villi isolated from archival formalin-fixed paraffin-embedded abortion material using laser microdissection. J Forensic Sci. 2006 Jan; 51(1):90-2. PMID: 16423229.
    Citations: 4     Fields:    Translation:HumansCells
  86. Inghirami G, Chiarle R, Simmons WJ, Piva R, Schlessinger K, Levy DE. New and old functions of STAT3: a pivotal target for individualized treatment of cancer. Cell Cycle. 2005 Sep; 4(9):1131-3. PMID: 16082218.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  87. Piva R, Chiarle R, Manazza AD, Taulli R, Simmons W, Ambrogio C, D'Escamard V, Pellegrino E, Ponzetto C, Palestro G, Inghirami G. Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas. Blood. 2006 Jan 15; 107(2):689-97. PMID: 16189272.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  88. Ambrogio C, Voena C, Manazza AD, Piva R, Riera L, Barberis L, Costa C, Tarone G, Defilippi P, Hirsch E, Boeri Erba E, Mohammed S, Jensen ON, Palestro G, Inghirami G, Chiarle R. p130Cas mediates the transforming properties of the anaplastic lymphoma kinase. Blood. 2005 Dec 01; 106(12):3907-16. PMID: 16105984.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  89. Manazza AD, Bonello L, Pagano M, Chiusa L, Novero D, Stacchini A, Martini G, Vitolo U, Tarella C, Inghirami G, Palestro G, Chiarle R. Follicular origin of a subset of CD5+ diffuse large B-cell lymphomas. Am J Clin Pathol. 2005 Aug; 124(2):182-90. PMID: 16040287.
    Citations: 2     Fields:    Translation:Humans
  90. Chiarle R, Simmons WJ, Cai H, Dhall G, Zamo A, Raz R, Karras JG, Levy DE, Inghirami G. Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target. Nat Med. 2005 Jun; 11(6):623-9. PMID: 15895073.
    Citations: 148     Fields:    Translation:HumansAnimalsCells
  91. Taulli R, Accornero P, Follenzi A, Mangano T, Morotti A, Scuoppo C, Forni PE, Bersani F, Crepaldi T, Chiarle R, Naldini L, Ponzetto C. RNAi technology and lentiviral delivery as a powerful tool to suppress Tpr-Met-mediated tumorigenesis. Cancer Gene Ther. 2005 May; 12(5):456-63. PMID: 15719029.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  92. Maritano D, Sugrue ML, Tininini S, Dewilde S, Strobl B, Fu X, Murray-Tait V, Chiarle R, Poli V. The STAT3 isoforms alpha and beta have unique and specific functions. Nat Immunol. 2004 Apr; 5(4):401-9. PMID: 15021879.
    Citations: 64     Fields:    Translation:Animals
  93. Papotti M, Manazza AD, Chiarle R, Bussolati G. Confocal microscope analysis and tridimensional reconstruction of papillary thyroid carcinoma nuclei. Virchows Arch. 2004 Apr; 444(4):350-5. PMID: 14758551.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  94. Buttiglieri S, Deregibus MC, Bravo S, Cassoni P, Chiarle R, Bussolati B, Camussi G. Role of Pax2 in apoptosis resistance and proinvasive phenotype of Kaposi's sarcoma cells. J Biol Chem. 2004 Feb 06; 279(6):4136-43. PMID: 14627715.
    Citations: 21     Fields:    Translation:HumansCells
  95. Bonello L, Voena C, Ladetto M, Boccadoro M, Palestro G, Inghirami G, Chiarle R. BRAF gene is not mutated in plasma cell leukemia and multiple myeloma. Leukemia. 2003 Nov; 17(11):2238-40. PMID: 12931219.
    Citations: 7     Fields:    Translation:HumansCells
  96. Stacchini A, Chiarle R, Antinoro V, Demurtas A, Novero D, Palestro G. Expression of the CD31 antigen in normal B-cells and non Hodgkin's lymphomas. J Biol Regul Homeost Agents. 2003 Oct-Dec; 17(4):308-15. PMID: 15065759.
    Citations: 2     Fields:    Translation:HumansCells
  97. Chiarle R, Inghirami G, Palestro G. Role of CD30 in the maturation of thymocytes and in the pathogenesis of autoimmune diseases. Pathologica. 2003 Oct; 95(5):229-30. PMID: 14988980.
    Citations:    Fields:    Translation:HumansCells
  98. Sapino A, Cassoni P, Ferrero E, Bongiovanni M, Righi L, Fortunati N, Crafa P, Chiarle R, Bussolati G. Estrogen receptor alpha is a novel marker expressed by follicular dendritic cells in lymph nodes and tumor-associated lymphoid infiltrates. Am J Pathol. 2003 Oct; 163(4):1313-20. PMID: 14507640.
    Citations: 9     Fields:    Translation:HumansCells
  99. Piva R, Liu J, Chiarle R, Podda A, Pagano M, Inghirami G. In vivo interference with Skp1 function leads to genetic instability and neoplastic transformation. Mol Cell Biol. 2002 Dec; 22(23):8375-87. PMID: 12417738.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  100. Chiarle R, Gong JZ, Guasparri I, Pesci A, Cai J, Liu J, Simmons WJ, Dhall G, Howes J, Piva R, Inghirami G. NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors. Blood. 2003 Mar 01; 101(5):1919-27. PMID: 12424201.
    Citations: 62     Fields:    Translation:AnimalsCells
  101. Chiarle R, Fan Y, Piva R, Boggino H, Skolnik J, Novero D, Palestro G, De Wolf-Peeters C, Chilosi M, Pagano M, Inghirami G. S-phase kinase-associated protein 2 expression in non-Hodgkin's lymphoma inversely correlates with p27 expression and defines cells in S phase. Am J Pathol. 2002 Apr; 160(4):1457-66. PMID: 11943729.
    Citations: 20     Fields:    Translation:HumansCells
  102. Zamo A, Chiarle R, Piva R, Howes J, Fan Y, Chilosi M, Levy DE, Inghirami G. Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death. Oncogene. 2002 Feb 07; 21(7):1038-47. PMID: 11850821.
    Citations: 96     Fields:    Translation:HumansAnimalsCells
  103. Latres E, Chiarle R, Schulman BA, Pavletich NP, Pellicer A, Inghirami G, Pagano M. Role of the F-box protein Skp2 in lymphomagenesis. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2515-20. PMID: 11226270.
    Citations: 89     Fields:    Translation:HumansAnimals
  104. Simmons WJ, Simms M, Chiarle R, Mackay F, Tsiagbe VK, Browning J, Inghirami G, Thorbecke GJ. Induction of germinal centers by MMTV encoded superantigen on B cells. Dev Immunol. 2001; 8(3-4):201-11. PMID: 11785670.
    Citations:    Fields:    Translation:AnimalsCells
  105. Chiarle R, Pagano M, Inghirami G. The cyclin dependent kinase inhibitor p27 and its prognostic role in breast cancer. Breast Cancer Res. 2001; 3(2):91-4. PMID: 11250752.
    Citations: 23     Fields:    Translation:Humans
  106. Chilosi M, Chiarle R, Lestani M, Menestrina F, Montagna L, Ambrosetti A, Prolla G, Pizzolo G, Doglioni C, Piva R, Pagano M, Inghirami G. Low expression of p27 and low proliferation index do not correlate in hairy cell leukaemia. Br J Haematol. 2000 Oct; 111(1):263-71. PMID: 11091210.
    Citations: 4     Fields:    Translation:Humans
  107. Miravalle L, Tokuda T, Chiarle R, Giaccone G, Bugiani O, Tagliavini F, Frangione B, Ghiso J. Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells. J Biol Chem. 2000 Sep 01; 275(35):27110-6. PMID: 10821838.
    Citations: 61     Fields:    Translation:HumansCells
  108. Liu J, Prolla G, Rostagno A, Chiarle R, Feiner H, Inghirami G. Initiation of translation from a downstream in-frame AUG codon on BRCA1 can generate the novel isoform protein DeltaBRCA1(17aa). Oncogene. 2000 May 25; 19(23):2767-73. PMID: 10851077.
    Citations: 10     Fields:    Translation:HumansCells
  109. Chiarle R, Budel LM, Skolnik J, Frizzera G, Chilosi M, Corato A, Pizzolo G, Magidson J, Montagnoli A, Pagano M, Maes B, De Wolf-Peeters C, Inghirami G. Increased proteasome degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma. Blood. 2000 Jan 15; 95(2):619-26. PMID: 10627471.
    Citations: 27     Fields:    Translation:HumansCells
  110. Gong JZ, Zheng S, Chiarle R, De Wolf-Peeters C, Palestro G, Frizzera G, Inghirami G. Detection of immunoglobulin kappa light chain rearrangements by polymerase chain reaction. An improved method for detecting clonal B-cell lymphoproliferative disorders. Am J Pathol. 1999 Aug; 155(2):355-63. PMID: 10433929.
    Citations: 13     Fields:    Translation:HumansCells
  111. Chiarle R, Podda A, Prolla G, Podack ER, Thorbecke GJ, Inghirami G. CD30 overexpression enhances negative selection in the thymus and mediates programmed cell death via a Bcl-2-sensitive pathway. J Immunol. 1999 Jul 01; 163(1):194-205. PMID: 10384116.
    Citations: 23     Fields:    Translation:AnimalsCells
  112. Chiarle R, Podda A, Prolla G, Gong J, Thorbecke GJ, Inghirami G. CD30 in normal and neoplastic cells. Clin Immunol. 1999 Feb; 90(2):157-64. PMID: 10080826.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  113. Gaidano G, Volpe G, Pastore C, Chiarle R, Capello D, Gloghini A, Perissinotto E, Savinelli F, Bosco M, Mazza U, Pileri S, Palestro G, Carbone A, Saglio G. Detection of BCL-6 rearrangements and p53 mutations in Malt-lymphomas. Am J Hematol. 1997 Dec; 56(4):206-13. PMID: 9395180.
    Citations: 2     Fields:    Translation:HumansCells
  114. Palestro G, Ponti R, Chiusa L, Chiarle R, Geuna M, Novero D, Freilone R, Pich A. Cell proliferation, bcl-2, c-myc, p53 and apoptosis as indicators of different aggressiveness in small lymphocytic lymphoma (SLL). Eur J Haematol. 1997 Sep; 59(3):148-54. PMID: 9310122.
    Citations:    Fields:    Translation:Humans
  115. Chiarle R, Godio L, Fusi D, Soldati T, Palestro G. Pure alveolar rhabdomyosarcoma of the corpus uteri: description of a case with increased serum level of CA-125. Gynecol Oncol. 1997 Aug; 66(2):320-3. PMID: 9264583.
    Citations: 2     Fields:    Translation:Humans
  116. Pich A, Chiarle R, Chiusa L, Ponti R, Geuna M, Palestro G. p53 expression and proliferative activity predict survival in non-invasive thymomas. Int J Cancer. 1996 Jun 21; 69(3):180-3. PMID: 8682584.
    Citations: 2     Fields:    Translation:HumansCells
  117. Pich A, Chiarle R, Chiusa L, Ponti R, Geuna M, Casadio C, Maggi G, Palestro G. Long-term survival of thymoma patients by histologic pattern and proliferative activity. Am J Surg Pathol. 1995 Aug; 19(8):918-26. PMID: 7611538.
    Citations: 1     Fields:    Translation:HumansCells
  118. Pilotti S, Manenti G, De Gregorio L, Rilke F, Chiarle R, Pierotti MA. Identification of the same HRAS1 mutation in a primary minimally invasive follicular carcinoma of the thyroid gland and its bone metastasis developed 15 years later. Diagn Mol Pathol. 1995 Mar; 4(1):73-4. PMID: 7735560.
    Citations: 1     Fields:    Translation:Humans
  119. Pich A, Chiarle R, Chiusa L, Palestro G. Argyrophilic nucleolar organizer region counts predict survival in thymoma. Cancer. 1994 Sep 01; 74(5):1568-74. PMID: 7520349.
    Citations: 1     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.