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David L. Paul, Ph.D.

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Mentoring
Connexin50 requires p150 to form Gap Junctions
Summer, 06/20/11 - 08/12/11

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01EY014127 (PAUL, DAVID L) Jul 1, 2002 - Jun 30, 2013
    NIH/NEI
    Connexins and electrical synapses in the retina
    Role: Principal Investigator
  2. T32AG000222 (YANKNER, BRUCE A) Sep 30, 1992 - Apr 30, 2022
    NIH/NIA
    Training in the Molecular Biology of Neurodegeneration and Alzheimer's Disease
    Role: Co-Principal Investigator
  3. R01GM037751 (PAUL, DAVID L) Dec 1, 1986 - Jun 30, 2012
    NIH/NIGMS
    Function and Regulation of Intercellular Communication
    Role: Principal Investigator
  4. R01EY002430 (PAUL, DAVID L) Mar 1, 1978 - Mar 31, 2013
    NIH/NEI
    Connexin Molecular Biology in the Lens and Ciliary Epithelium
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhang Q, Lee WA, Paul DL, Ginty DD. Multiplexed peroxidase-based electron microscopy labeling enables simultaneous visualization of multiple cell types. Nat Neurosci. 2019 05; 22(5):828-839. PMID: 30886406.
    Citations:    
  2. Yao X, Cafaro J, McLaughlin AJ, Postma FR, Paul DL, Awatramani G, Field GD. Gap Junctions Contribute to Differential Light Adaptation across Direction-Selective Retinal Ganglion Cells. Neuron. 2018 Oct 10; 100(1):216-228.e6. PMID: 30220512.
    Citations:    
  3. Plautz WE, Sekhar Pilli VS, Cooley BC, Chattopadhyay R, Westmark PR, Getz T, Paul D, Bergmeier W, Sheehan JP, Majumder R. Anticoagulant Protein S Targets the Factor IXa Heparin-Binding Exosite to Prevent Thrombosis. Arterioscler Thromb Vasc Biol. 2018 04; 38(4):816-828. PMID: 29419409.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  4. Tosur M, Tomsa A, Paul DL. Diencephalic syndrome: a rare cause of failure to thrive. BMJ Case Rep. 2017 Jul 06; 2017. PMID: 28687692.
    Citations:    Fields:    Translation:Humans
  5. Paul DL, McDaniel RR. Influences on teleconsultation project utilization rates: the role of dominant logic. BMC Med Inform Decis Mak. 2016 12 08; 16(1):155. PMID: 27931219.
    Citations:    Fields:    Translation:Humans
  6. Paul DL, McDaniel RR. Facilitating telemedicine project sustainability in medically underserved areas: a healthcare provider participant perspective. BMC Health Serv Res. 2016 Apr 26; 16:148. PMID: 27112268.
    Citations:    Fields:    Translation:Humans
  7. Munger SJ, Geng X, Srinivasan RS, Witte MH, Paul DL, Simon AM. Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016 Apr 15; 412(2):173-90. PMID: 26953188.
    Citations: 7     Fields:    Translation:Animals
  8. Cowan CS, Abd-El-Barr M, van der Heijden M, Lo EM, Paul D, Bramblett DE, Lem J, Simons DL, Wu SM. Connexin 36 and rod bipolar cell independent rod pathways drive retinal ganglion cells and optokinetic reflexes. Vision Res. 2016 Feb; 119:99-109. PMID: 26718442.
    Citations: 8     Fields:    Translation:AnimalsCells
  9. Kim FJ, da Silva RD, Gustafson D, Nogueira L, Harlin T, Paul DL. Current issues in patient safety in surgery: a review. Patient Saf Surg. 2015; 9:26. PMID: 26045717.
    Citations: 2     
  10. Akopian A, Atlasz T, Pan F, Wong S, Zhang Y, Völgyi B, Paul DL, Bloomfield SA. Gap junction-mediated death of retinal neurons is connexin and insult specific: a potential target for neuroprotection. J Neurosci. 2014 Aug 06; 34(32):10582-91. PMID: 25100592.
    Citations: 13     Fields:    Translation:AnimalsCells
  11. Pizarro-Delgado J, Fasciani I, Temperan A, Romero M, González-Nieto D, Alonso-Magdalena P, Nualart-Marti A, Estil'les E, Paul DL, Martín-del-Río R, Montanya E, Solsona C, Nadal A, Barrio LC, Tamarit-Rodríguez J. Inhibition of connexin 36 hemichannels by glucose contributes to the stimulation of insulin secretion. Am J Physiol Endocrinol Metab. 2014 Jun 15; 306(12):E1354-66. PMID: 24735890.
    Citations: 1     Fields:    Translation:AnimalsCells
  12. Williams JL, Paul D, Bisset G. Thyroid disease in children: part 2 : State-of-the-art imaging in pediatric hyperthyroidism. Pediatr Radiol. 2013 Oct; 43(10):1254-64. PMID: 24057230.
    Citations: 1     Fields:    Translation:Humans
  13. Williams JL, Paul DL, Bisset G. Thyroid disease in children: part 1: State-of-the-art imaging in pediatric hypothyroidism. Pediatr Radiol. 2013 Oct; 43(10):1244-53. PMID: 24057229.
    Citations: 1     Fields:    Translation:Humans
  14. Hou M, Li Y, Paul DL. A novel, highly sensitive method for assessing gap junctional coupling. J Neurosci Methods. 2013 Oct 30; 220(1):18-23. PMID: 23958747.
    Citations: 3     Fields:    Translation:HumansCells
  15. Pang JJ, Paul DL, Wu SM. Survey on amacrine cells coupling to retrograde-identified ganglion cells in the mouse retina. Invest Ophthalmol Vis Sci. 2013 Aug 01; 54(8):5151-62. PMID: 23821205.
    Citations: 12     Fields:    Translation:AnimalsCells
  16. Völgyi B, Pan F, Paul DL, Wang JT, Huberman AD, Bloomfield SA. Gap junctions are essential for generating the correlated spike activity of neighboring retinal ganglion cells. PLoS One. 2013; 8(7):e69426. PMID: 23936012.
    Citations: 18     Fields:    Translation:AnimalsCells
  17. Pang JJ, Gao F, Paul DL, Wu SM. Rod, M-cone and M/S-cone inputs to hyperpolarizing bipolar cells in the mouse retina. J Physiol. 2012 Feb 15; 590(4):845-54. PMID: 22219344.
    Citations: 15     Fields:    Translation:AnimalsCells
  18. Chai Z, Goodenough DA, Paul DL. Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels. Mol Biol Cell. 2011 Dec; 22(23):4503-12. PMID: 21965293.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  19. Postma F, Liu CH, Dietsche C, Khan M, Lee HK, Paul D, Kanold PO. Electrical synapses formed by connexin36 regulate inhibition- and experience-dependent plasticity. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13770-5. PMID: 21804029.
    Citations: 7     Fields:    Translation:AnimalsCells
  20. Magnotti LM, Goodenough DA, Paul DL. Deletion of oligodendrocyte Cx32 and astrocyte Cx43 causes white matter vacuolation, astrocyte loss and early mortality. Glia. 2011 Jul; 59(7):1064-74. PMID: 21538560.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  21. Magnotti LM, Goodenough DA, Paul DL. Functional heterotypic interactions between astrocyte and oligodendrocyte connexins. Glia. 2011 Jan; 59(1):26-34. PMID: 21046554.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  22. Brown TM, Allen AE, Wynne J, Paul DL, Piggins HD, Lucas RJ. Visual responses in the lateral geniculate evoked by Cx36-independent rod pathways. Vision Res. 2011 Jan 28; 51(2):280-7. PMID: 20709095.
    Citations: 10     Fields:    Translation:AnimalsCells
  23. Pan F, Paul DL, Bloomfield SA, Völgyi B. Connexin36 is required for gap junctional coupling of most ganglion cell subtypes in the mouse retina. J Comp Neurol. 2010 Mar 15; 518(6):911-27. PMID: 20058323.
    Citations: 22     Fields:    Translation:AnimalsCells
  24. Pang JJ, Gao F, Lem J, Bramblett DE, Paul DL, Wu SM. Direct rod input to cone BCs and direct cone input to rod BCs challenge the traditional view of mammalian BC circuitry. Proc Natl Acad Sci U S A. 2010 Jan 05; 107(1):395-400. PMID: 20018684.
    Citations: 35     Fields:    Translation:AnimalsCells
  25. Hou J, Renigunta A, Gomes AS, Hou M, Paul DL, Waldegger S, Goodenough DA. Claudin-16 and claudin-19 interaction is required for their assembly into tight junctions and for renal reabsorption of magnesium. Proc Natl Acad Sci U S A. 2009 Sep 08; 106(36):15350-5. PMID: 19706394.
    Citations: 65     Fields:    Translation:AnimalsCells
  26. Abd-El-Barr MM, Pennesi ME, Saszik SM, Barrow AJ, Lem J, Bramblett DE, Paul DL, Frishman LJ, Wu SM. Genetic dissection of rod and cone pathways in the dark-adapted mouse retina. J Neurophysiol. 2009 Sep; 102(3):1945-55. PMID: 19587322.
    Citations: 47     Fields:    Translation:AnimalsCells
  27. Goodenough DA, Paul DL. Gap junctions. Cold Spring Harb Perspect Biol. 2009 Jul; 1(1):a002576. PMID: 20066080.
    Citations: 138     Fields:    Translation:HumansAnimalsCells
  28. Imbeault S, Gauvin LG, Toeg HD, Pettit A, Sorbara CD, Migahed L, DesRoches R, Menzies AS, Nishii K, Paul DL, Simon AM, Bennett SA. The extracellular matrix controls gap junction protein expression and function in postnatal hippocampal neural progenitor cells. BMC Neurosci. 2009 Feb 24; 10:13. PMID: 19236721.
    Citations: 19     Fields:    Translation:AnimalsCells
  29. Calera MR, Wang Z, Sanchez-Olea R, Paul DL, Civan MM, Goodenough DA. Depression of intraocular pressure following inactivation of connexin43 in the nonpigmented epithelium of the ciliary body. Invest Ophthalmol Vis Sci. 2009 May; 50(5):2185-93. PMID: 19168903.
    Citations: 7     Fields:    Translation:AnimalsCells
  30. Norris RP, Freudzon M, Mehlmann LM, Cowan AE, Simon AM, Paul DL, Lampe PD, Jaffe LA. Luteinizing hormone causes MAP kinase-dependent phosphorylation and closure of connexin 43 gap junctions in mouse ovarian follicles: one of two paths to meiotic resumption. Development. 2008 Oct; 135(19):3229-38. PMID: 18776144.
    Citations: 64     Fields:    Translation:AnimalsCells
  31. Cummings DM, Yamazaki I, Cepeda C, Paul DL, Levine MS. Neuronal coupling via connexin36 contributes to spontaneous synaptic currents of striatal medium-sized spiny neurons. J Neurosci Res. 2008 Aug 01; 86(10):2147-58. PMID: 18381762.
    Citations: 12     Fields:    Translation:AnimalsCells
  32. Ahn M, Lee J, Gustafsson A, Enriquez A, Lancaster E, Sul JY, Haydon PG, Paul DL, Huang Y, Abrams CK, Scherer SS. Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct. J Neurosci Res. 2008 Apr; 86(5):992-1006. PMID: 17972320.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  33. Hou J, Renigunta A, Konrad M, Gomes AS, Schneeberger EE, Paul DL, Waldegger S, Goodenough DA. Claudin-16 and claudin-19 interact and form a cation-selective tight junction complex. J Clin Invest. 2008 Feb; 118(2):619-28. PMID: 18188451.
    Citations: 88     Fields:    Translation:AnimalsCells
  34. Hou J, Shan Q, Wang T, Gomes AS, Yan Q, Paul DL, Bleich M, Goodenough DA. Transgenic RNAi depletion of claudin-16 and the renal handling of magnesium. J Biol Chem. 2007 Jun 08; 282(23):17114-22. PMID: 17442678.
    Citations: 45     Fields:    Translation:AnimalsCells
  35. Pang JJ, Abd-El-Barr MM, Gao F, Bramblett DE, Paul DL, Wu SM. Relative contributions of rod and cone bipolar cell inputs to AII amacrine cell light responses in the mouse retina. J Physiol. 2007 Apr 15; 580(Pt. 2):397-410. PMID: 17255172.
    Citations: 33     Fields:    Translation:AnimalsCells
  36. Menichella DM, Majdan M, Awatramani R, Goodenough DA, Sirkowski E, Scherer SS, Paul DL. Genetic and physiological evidence that oligodendrocyte gap junctions contribute to spatial buffering of potassium released during neuronal activity. J Neurosci. 2006 Oct 25; 26(43):10984-91. PMID: 17065440.
    Citations: 49     Fields:    Translation:AnimalsCells
  37. Calera MR, Topley HL, Liao Y, Duling BR, Paul DL, Goodenough DA. Connexin43 is required for production of the aqueous humor in the murine eye. J Cell Sci. 2006 Nov 01; 119(Pt 21):4510-9. PMID: 17046998.
    Citations: 14     Fields:    Translation:AnimalsCells
  38. Hou J, Gomes AS, Paul DL, Goodenough DA. Study of claudin function by RNA interference. J Biol Chem. 2006 Nov 24; 281(47):36117-23. PMID: 17018523.
    Citations: 73     Fields:    Translation:AnimalsCells
  39. Tang W, Zhang Y, Chang Q, Ahmad S, Dahlke I, Yi H, Chen P, Paul DL, Lin X. Connexin29 is highly expressed in cochlear Schwann cells, and it is required for the normal development and function of the auditory nerve of mice. J Neurosci. 2006 Feb 15; 26(7):1991-9. PMID: 16481432.
    Citations: 23     Fields:    Translation:AnimalsCells
  40. Völgyi B, Abrams J, Paul DL, Bloomfield SA. Morphology and tracer coupling pattern of alpha ganglion cells in the mouse retina. J Comp Neurol. 2005 Nov 07; 492(1):66-77. PMID: 16175559.
    Citations: 30     Fields:    Translation:AnimalsCells
  41. Zhu W, Saba S, Link MS, Bak E, Homoud MK, Estes NA, Paul DL, Wang PJ. Atrioventricular nodal reverse facilitation in connexin40-deficient mice. Heart Rhythm. 2005 Nov; 2(11):1231-7. PMID: 16253914.
    Citations: 6     Fields:    Translation:AnimalsCells
  42. Hou J, Paul DL, Goodenough DA. Paracellin-1 and the modulation of ion selectivity of tight junctions. J Cell Sci. 2005 Nov 01; 118(Pt 21):5109-18. PMID: 16234325.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  43. Pizard A, Burgon PG, Paul DL, Bruneau BG, Seidman CE, Seidman JG. Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum. Mol Cell Biol. 2005 Jun; 25(12):5073-83. PMID: 15923624.
    Citations: 13     Fields:    Translation:HumansAnimals
  44. McCracken CB, Patel KM, Vrana KE, Paul DL, Roberts DC. Amphetamine withdrawal produces region-specific and time-dependent changes in connexin36 expression in rat brain. Synapse. 2005 Apr; 56(1):39-44. PMID: 15700285.
    Citations: 3     Fields:    Translation:Animals
  45. Kosaka T, Deans MR, Paul DL, Kosaka K. Neuronal gap junctions in the mouse main olfactory bulb: morphological analyses on transgenic mice. Neuroscience. 2005; 134(3):757-69. PMID: 15979807.
    Citations: 9     Fields:    Translation:AnimalsCells
  46. Völgyi B, Deans MR, Paul DL, Bloomfield SA. Convergence and segregation of the multiple rod pathways in mammalian retina. J Neurosci. 2004 Dec 08; 24(49):11182-92. PMID: 15590935.
    Citations: 68     Fields:    Translation:AnimalsCells
  47. Stout C, Goodenough DA, Paul DL. Connexins: functions without junctions. Curr Opin Cell Biol. 2004 Oct; 16(5):507-12. PMID: 15363800.
    Citations: 60     Fields:    Translation:Cells
  48. Martinez-Wittinghan FJ, Sellitto C, White TW, Mathias RT, Paul D, Goodenough DA. Lens gap junctional coupling is modulated by connexin identity and the locus of gene expression. Invest Ophthalmol Vis Sci. 2004 Oct; 45(10):3629-37. PMID: 15452070.
    Citations: 24     Fields:    Translation:AnimalsCells
  49. Kleopa KA, Orthmann JL, Enriquez A, Paul DL, Scherer SS. Unique distributions of the gap junction proteins connexin29, connexin32, and connexin47 in oligodendrocytes. Glia. 2004 Sep; 47(4):346-57. PMID: 15293232.
    Citations: 39     Fields:    Translation:AnimalsCells
  50. Altevogt BM, Paul DL. Four classes of intercellular channels between glial cells in the CNS. J Neurosci. 2004 May 05; 24(18):4313-23. PMID: 15128845.
    Citations: 51     Fields:    Translation:AnimalsCells
  51. Blinder KJ, Pumplin DW, Paul DL, Keller A. Intercellular interactions in the mammalian olfactory nerve. J Comp Neurol. 2003 Nov 10; 466(2):230-9. PMID: 14528450.
    Citations: 7     Fields:    Translation:AnimalsCells
  52. Menichella DM, Goodenough DA, Sirkowski E, Scherer SS, Paul DL. Connexins are critical for normal myelination in the CNS. J Neurosci. 2003 Jul 02; 23(13):5963-73. PMID: 12843301.
    Citations: 79     Fields:    Translation:AnimalsCells
  53. Goodenough DA, Paul DL. Beyond the gap: functions of unpaired connexon channels. Nat Rev Mol Cell Biol. 2003 Apr; 4(4):285-94. PMID: 12671651.
    Citations: 211     Fields:    Translation:HumansAnimalsCells
  54. Figueroa XF, Paul DL, Simon AM, Goodenough DA, Day KH, Damon DN, Duling BR. Central role of connexin40 in the propagation of electrically activated vasodilation in mouse cremasteric arterioles in vivo. Circ Res. 2003 Apr 18; 92(7):793-800. PMID: 12637364.
    Citations: 48     Fields:    Translation:Animals
  55. Melanson-Drapeau L, Beyko S, Davé S, Hebb AL, Franks DJ, Sellitto C, Paul DL, Bennett SA. Oligodendrocyte progenitor enrichment in the connexin32 null-mutant mouse. J Neurosci. 2003 Mar 01; 23(5):1759-68. PMID: 12629180.
    Citations: 10     Fields:    Translation:AnimalsCells
  56. Kasahara H, Ueyama T, Wakimoto H, Liu MK, Maguire CT, Converso KL, Kang PM, Manning WJ, Lawitts J, Paul DL, Berul CI, Izumo S. Nkx2.5 homeoprotein regulates expression of gap junction protein connexin 43 and sarcomere organization in postnatal cardiomyocytes. J Mol Cell Cardiol. 2003 Mar; 35(3):243-56. PMID: 12676539.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  57. Landesman Y, Postma FR, Goodenough DA, Paul DL. Multiple connexins contribute to intercellular communication in the Xenopus embryo. J Cell Sci. 2003 Jan 01; 116(Pt 1):29-38. PMID: 12456713.
    Citations: 5     Fields:    Translation:AnimalsCells
  58. Long MA, Deans MR, Paul DL, Connors BW. Rhythmicity without synchrony in the electrically uncoupled inferior olive. J Neurosci. 2002 Dec 15; 22(24):10898-905. PMID: 12486184.
    Citations: 73     Fields:    Translation:AnimalsCells
  59. Deans MR, Volgyi B, Goodenough DA, Bloomfield SA, Paul DL. Connexin36 is essential for transmission of rod-mediated visual signals in the mammalian retina. Neuron. 2002 Nov 14; 36(4):703-12. PMID: 12441058.
    Citations: 141     Fields:    Translation:AnimalsCells
  60. Altevogt BM, Kleopa KA, Postma FR, Scherer SS, Paul DL. Connexin29 is uniquely distributed within myelinating glial cells of the central and peripheral nervous systems. J Neurosci. 2002 Aug 01; 22(15):6458-70. PMID: 12151525.
    Citations: 67     Fields:    Translation:AnimalsCells
  61. Landesman Y, Goodenough DA, Paul DL. Xwnt-2 (Xwnt-2b) is maternally expressed in Xenopus oocytes and embryos. Biochim Biophys Acta. 2002 Jul 19; 1576(3):265-8. PMID: 12084573.
    Citations:    Fields:    Translation:AnimalsCells
  62. Landisman CE, Long MA, Beierlein M, Deans MR, Paul DL, Connors BW. Electrical synapses in the thalamic reticular nucleus. J Neurosci. 2002 Feb 01; 22(3):1002-9. PMID: 11826128.
    Citations: 115     Fields:    Translation:AnimalsCells
  63. White TW, Sellitto C, Paul DL, Goodenough DA. Prenatal lens development in connexin43 and connexin50 double knockout mice. Invest Ophthalmol Vis Sci. 2001 Nov; 42(12):2916-23. PMID: 11687537.
    Citations: 12     Fields:    Translation:AnimalsCells
  64. Deans MR, Gibson JR, Sellitto C, Connors BW, Paul DL. Synchronous activity of inhibitory networks in neocortex requires electrical synapses containing connexin36. Neuron. 2001 Aug 16; 31(3):477-85. PMID: 11516403.
    Citations: 160     Fields:    Translation:AnimalsCells
  65. Kasahara H, Wakimoto H, Liu M, Maguire CT, Converso KL, Shioi T, Huang WY, Manning WJ, Paul D, Lawitts J, Berul CI, Izumo S. Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein. J Clin Invest. 2001 Jul; 108(2):189-201. PMID: 11457872.
    Citations: 34     Fields:    Translation:AnimalsCells
  66. Rouan F, White TW, Brown N, Taylor AM, Lucke TW, Paul DL, Munro CS, Uitto J, Hodgins MB, Richard G. trans-dominant inhibition of connexin-43 by mutant connexin-26: implications for dominant connexin disorders affecting epidermal differentiation. J Cell Sci. 2001 Jun; 114(Pt 11):2105-13. PMID: 11493646.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  67. Deans MR, Paul DL. Mouse horizontal cells do not express connexin26 or connexin36. Cell Commun Adhes. 2001; 8(4-6):361-6. PMID: 12064619.
    Citations: 11     Fields:    Translation:AnimalsCells
  68. Tamaddon HS, Vaidya D, Simon AM, Paul DL, Jalife J, Morley GE. High-resolution optical mapping of the right bundle branch in connexin40 knockout mice reveals slow conduction in the specialized conduction system. Circ Res. 2000 Nov 10; 87(10):929-36. PMID: 11073890.
    Citations: 49     Fields:    Translation:AnimalsCells
  69. VanderBrink BA, Sellitto C, Saba S, Link MS, Zhu W, Homoud MK, Estes NA, Paul DL, Wang PJ. Connexin40-deficient mice exhibit atrioventricular nodal and infra-Hisian conduction abnormalities. J Cardiovasc Electrophysiol. 2000 Nov; 11(11):1270-6. PMID: 11083248.
    Citations: 19     Fields:    Translation:Animals
  70. Bevilacqua LM, Simon AM, Maguire CT, Gehrmann J, Wakimoto H, Paul DL, Berul CI. A targeted disruption in connexin40 leads to distinct atrioventricular conduction defects. J Interv Card Electrophysiol. 2000 Oct; 4(3):459-67. PMID: 11046183.
    Citations: 16     Fields:    Translation:AnimalsCells
  71. Landesman Y, Goodenough DA, Paul DL. Gap junctional communication in the early Xenopus embryo. J Cell Biol. 2000 Aug 21; 150(4):929-36. PMID: 10953017.
    Citations: 6     Fields:    Translation:AnimalsCells
  72. Che YH, Li Y, Slavik M, Paul D. Rapid detection of Salmonella typhimurium in chicken carcass wash water using an immunoelectrochemical method. J Food Prot. 2000 Aug; 63(8):1043-8. PMID: 10945578.
    Citations: 3     Fields:    Translation:AnimalsCellsPHPublic Health
  73. Ryeom SW, Paul D, Goodenough DA. Truncation mutants of the tight junction protein ZO-1 disrupt corneal epithelial cell morphology. Mol Biol Cell. 2000 May; 11(5):1687-96. PMID: 10793144.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  74. Kikuchi T, Kimura RS, Paul DL, Takasaka T, Adams JC. Gap junction systems in the mammalian cochlea. Brain Res Brain Res Rev. 2000 Apr; 32(1):163-6. PMID: 10751665.
    Citations: 69     Fields:    Translation:AnimalsCells
  75. Muresan Z, Paul DL, Goodenough DA. Occludin 1B, a variant of the tight junction protein occludin. Mol Biol Cell. 2000 Feb; 11(2):627-34. PMID: 10679019.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  76. Keon BH, Jedrzejewski PT, Paul DL, Goodenough DA. Isoform specific expression of the neuronal F-actin binding protein, drebrin, in specialized cells of stomach and kidney epithelia. J Cell Sci. 2000 Jan; 113 Pt 2:325-36. PMID: 10633083.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  77. Bennett SA, Arnold JM, Chen J, Stenger J, Paul DL, Roberts DC. Long-term changes in connexin32 gap junction protein and mRNA expression following cocaine self-administration in rats. Eur J Neurosci. 1999 Sep; 11(9):3329-38. PMID: 10510198.
    Citations: 4     Fields:    Translation:AnimalsCells
  78. Landesman Y, White TW, Starich TA, Shaw JE, Goodenough DA, Paul DL. Innexin-3 forms connexin-like intercellular channels. J Cell Sci. 1999 Jul; 112 ( Pt 14):2391-6. PMID: 10381394.
    Citations: 18     Fields:    Translation:AnimalsCells
  79. Goodenough DA, Simon AM, Paul DL. Gap junctional intercellular communication in the mouse ovarian follicle. Novartis Found Symp. 1999; 219:226-35; discussion 235-40. PMID: 10207907.
    Citations: 6     Fields:    Translation:AnimalsCells
  80. White TW, Paul DL. Genetic diseases and gene knockouts reveal diverse connexin functions. Annu Rev Physiol. 1999; 61:283-310. PMID: 10099690.
    Citations: 77     Fields:    Translation:HumansAnimals
  81. White TW, Goodenough DA, Paul DL. Targeted ablation of connexin50 in mice results in microphthalmia and zonular pulverulent cataracts. J Cell Biol. 1998 Nov 02; 143(3):815-25. PMID: 9813099.
    Citations: 120     Fields:    Translation:HumansAnimals
  82. Richard G, White TW, Smith LE, Bailey RA, Compton JG, Paul DL, Bale SJ. Functional defects of Cx26 resulting from a heterozygous missense mutation in a family with dominant deaf-mutism and palmoplantar keratoderma. Hum Genet. 1998 Oct; 103(4):393-9. PMID: 9856479.
    Citations: 51     Fields:    Translation:HumansCells
  83. Gabriels JE, Paul DL. Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed. Circ Res. 1998 Sep 21; 83(6):636-43. PMID: 9742059.
    Citations: 53     Fields:    Translation:Animals
  84. White TW, Deans MR, Kelsell DP, Paul DL. Connexin mutations in deafness. Nature. 1998 Aug 13; 394(6694):630-1. PMID: 9716127.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  85. Hoshino T, Jiang YZ, Dunn D, Paul D, Qazilbash M, Cowan K, Wang J, Barrett J, Liu J. Transfection of interleukin-12 cDNAs into tumor cells induces cytotoxic immune responses against native tumor: implications for tumor vaccination. Cancer Gene Ther. 1998 May-Jun; 5(3):150-7. PMID: 9622098.
    Citations:    Fields:    Translation:HumansCells
  86. Simon AM, Goodenough DA, Paul DL. Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block. Curr Biol. 1998 Feb 26; 8(5):295-8. PMID: 9501069.
    Citations: 79     Fields:    Translation:Animals
  87. Chen Y, Merzdorf C, Paul DL, Goodenough DA. COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J Cell Biol. 1997 Aug 25; 138(4):891-9. PMID: 9265654.
    Citations: 73     Fields:    Translation:AnimalsCells
  88. Simon AM, Goodenough DA, Li E, Paul DL. Female infertility in mice lacking connexin 37. Nature. 1997 Feb 06; 385(6616):525-9. PMID: 9020357.
    Citations: 116     Fields:    Translation:AnimalsCells
  89. Goliger JA, Bruzzone R, White TW, Paul DL. Dominant inhibition of intercellular communication by two chimeric connexins. Clin Exp Pharmacol Physiol. 1996 Dec; 23(12):1062-7. PMID: 8977161.
    Citations: 1     Fields:    Translation:AnimalsCells
  90. Van Kempen MJ, Vermeulen JL, Moorman AF, Gros D, Paul DL, Lamers WH. Developmental changes of connexin40 and connexin43 mRNA distribution patterns in the rat heart. Cardiovasc Res. 1996 Nov; 32(5):886-900. PMID: 8944820.
    Citations: 18     Fields:    Translation:Animals
  91. Tan IP, Roy C, Sáez JC, Sáez CG, Paul DL, Risley MS. Regulated assembly of connexin33 and connexin43 into rat Sertoli cell gap junctions. Biol Reprod. 1996 Jun; 54(6):1300-10. PMID: 8724358.
    Citations: 13     Fields:    Translation:AnimalsCells
  92. Bruzzone R, White TW, Paul DL. Connections with connexins: the molecular basis of direct intercellular signaling. Eur J Biochem. 1996 May 15; 238(1):1-27. PMID: 8665925.
    Citations: 207     Fields:    Translation:HumansAnimalsCells
  93. Goodenough DA, Goliger JA, Paul DL. Connexins, connexons, and intercellular communication. Annu Rev Biochem. 1996; 65:475-502. PMID: 8811187.
    Citations: 237     Fields:    Translation:AnimalsCells
  94. Scherer SS, Deschênes SM, Xu YT, Grinspan JB, Fischbeck KH, Paul DL. Connexin32 is a myelin-related protein in the PNS and CNS. J Neurosci. 1995 Dec; 15(12):8281-94. PMID: 8613761.
    Citations: 75     Fields:    Translation:AnimalsCells
  95. Goliger JA, Paul DL. Wounding alters epidermal connexin expression and gap junction-mediated intercellular communication. Mol Biol Cell. 1995 Nov; 6(11):1491-501. PMID: 8589451.
    Citations: 40     Fields:    Translation:AnimalsCells
  96. Paul DL. New functions for gap junctions. Curr Opin Cell Biol. 1995 Oct; 7(5):665-72. PMID: 8573341.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  97. White TW, Bruzzone R, Paul DL. The connexin family of intercellular channel forming proteins. Kidney Int. 1995 Oct; 48(4):1148-57. PMID: 8569076.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  98. Neveu MJ, Hully JR, Babcock KL, Vaughan J, Hertzberg EL, Nicholson BJ, Paul DL, Pitot HC. Proliferation-associated differences in the spatial and temporal expression of gap junction genes in rat liver. Hepatology. 1995 Jul; 22(1):202-12. PMID: 7601414.
    Citations: 12     Fields:    Translation:AnimalsCells
  99. Kojima T, Mitaka T, Paul DL, Mori M, Mochizuki Y. Reappearance and long-term maintenance of connexin32 in proliferated adult rat hepatocytes: use of serum-free L-15 medium supplemented with EGF and DMSO. J Cell Sci. 1995 Apr; 108 ( Pt 4):1347-57. PMID: 7615657.
    Citations: 7     Fields:    Translation:AnimalsCells
  100. White TW, Paul DL, Goodenough DA, Bruzzone R. Functional analysis of selective interactions among rodent connexins. Mol Biol Cell. 1995 Apr; 6(4):459-70. PMID: 7542941.
    Citations: 49     Fields:    Translation:AnimalsCells
  101. Kikuchi T, Kimura RS, Paul DL, Adams JC. Gap junctions in the rat cochlea: immunohistochemical and ultrastructural analysis. Anat Embryol (Berl). 1995 Feb; 191(2):101-18. PMID: 7726389.
    Citations: 116     Fields:    Translation:AnimalsCells
  102. Paul DL, Yu K, Bruzzone R, Gimlich RL, Goodenough DA. Expression of a dominant negative inhibitor of intercellular communication in the early Xenopus embryo causes delamination and extrusion of cells. Development. 1995 Feb; 121(2):371-81. PMID: 7768179.
    Citations: 14     Fields:    Translation:AnimalsCells
  103. Bruzzone R, White TW, Yoshizaki G, Patiño R, Paul DL. Intercellular channels in teleosts: functional characterization of two connexins from Atlantic croaker. FEBS Lett. 1995 Jan 30; 358(3):301-4. PMID: 7531161.
    Citations: 5     Fields:    Translation:AnimalsCells
  104. Neveu MJ, Sattler CA, Sattler GL, Hully JR, Hertzberg EL, Paul DL, Nicholson BJ, Pitot HC. Differences in the expression of connexin genes in rat hepatomas in vivo and in vitro. Mol Carcinog. 1994 Nov; 11(3):145-54. PMID: 7945803.
    Citations: 4     Fields:    Translation:AnimalsCells
  105. Bruzzone R, White TW, Scherer SS, Fischbeck KH, Paul DL. Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease. Neuron. 1994 Nov; 13(5):1253-60. PMID: 7946361.
    Citations: 23     Fields:    Translation:AnimalsCells
  106. White TW, Bruzzone R, Goodenough DA, Paul DL. Voltage gating of connexins. Nature. 1994 Sep 15; 371(6494):208-9. PMID: 8078580.
    Citations: 19     Fields:    Translation:AnimalsCells
  107. Kikuchi T, Adams JC, Paul DL, Kimura RS. Gap junction systems in the rat vestibular labyrinth: immunohistochemical and ultrastructural analysis. Acta Otolaryngol. 1994 Sep; 114(5):520-8. PMID: 7825434.
    Citations: 12     Fields:    Translation:AnimalsCells
  108. Ren P, de Feijter AW, Paul DL, Ruch RJ. Enhancement of liver cell gap junction protein expression by glucocorticoids. Carcinogenesis. 1994 Sep; 15(9):1807-13. PMID: 7522979.
    Citations: 11     Fields:    Translation:AnimalsCells
  109. Neveu MJ, Babcock KL, Hertzberg EL, Paul DL, Nicholson BJ, Pitot HC. Colocalized alterations in connexin32 and cytochrome P450IIB1/2 by phenobarbital and related liver tumor promoters. Cancer Res. 1994 Jun 15; 54(12):3145-52. PMID: 8205533.
    Citations: 13     Fields:    Translation:AnimalsCells
  110. Goliger JA, Paul DL. Expression of gap junction proteins Cx26, Cx31.1, Cx37, and Cx43 in developing and mature rat epidermis. Dev Dyn. 1994 May; 200(1):1-13. PMID: 8081010.
    Citations: 24     Fields:    Translation:AnimalsCells
  111. White TW, Bruzzone R, Wolfram S, Paul DL, Goodenough DA. Selective interactions among the multiple connexin proteins expressed in the vertebrate lens: the second extracellular domain is a determinant of compatibility between connexins. J Cell Biol. 1994 May; 125(4):879-92. PMID: 8188753.
    Citations: 79     Fields:    Translation:AnimalsCells
  112. Bruzzone R, White TW, Paul DL. Expression of chimeric connexins reveals new properties of the formation and gating behavior of gap junction channels. J Cell Sci. 1994 Apr; 107 ( Pt 4):955-67. PMID: 8056849.
    Citations: 14     Fields:    Translation:AnimalsCells
  113. Jiang JX, White TW, Goodenough DA, Paul DL. Molecular cloning and functional characterization of chick lens fiber connexin 45.6. Mol Biol Cell. 1994 Mar; 5(3):363-73. PMID: 8049527.
    Citations: 25     Fields:    Translation:AnimalsCells
  114. Neveu MJ, Hully JR, Babcock KL, Hertzberg EL, Nicholson BJ, Paul DL, Pitot HC. Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver. J Cell Sci. 1994 Jan; 107 ( Pt 1):83-95. PMID: 8175925.
    Citations: 18     Fields:    Translation:AnimalsCells
  115. Bergoffen J, Scherer SS, Wang S, Scott MO, Bone LJ, Paul DL, Chen K, Lensch MW, Chance PF, Fischbeck KH. Connexin mutations in X-linked Charcot-Marie-Tooth disease. Science. 1993 Dec 24; 262(5142):2039-42. PMID: 8266101.
    Citations: 172     Fields:    Translation:HumansAnimalsCells
  116. Jiang JX, Paul DL, Goodenough DA. Posttranslational phosphorylation of lens fiber connexin46: a slow occurrence. Invest Ophthalmol Vis Sci. 1993 Dec; 34(13):3558-65. PMID: 8258513.
    Citations: 14     Fields:    Translation:AnimalsCells
  117. Meda P, Pepper MS, Traub O, Willecke K, Gros D, Beyer E, Nicholson B, Paul D, Orci L. Differential expression of gap junction connexins in endocrine and exocrine glands. Endocrinology. 1993 Nov; 133(5):2371-8. PMID: 8404689.
    Citations: 32     Fields:    Translation:Animals
  118. Bruzzone R, Haefliger JA, Gimlich RL, Paul DL. Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins. Mol Biol Cell. 1993 Jan; 4(1):7-20. PMID: 8382974.
    Citations: 62     Fields:    Translation:AnimalsCells
  119. Harris AL, Walter A, Paul D, Goodenough DA, Zimmerberg J. Ion channels in single bilayers induced by rat connexin32. Brain Res Mol Brain Res. 1992 Oct; 15(3-4):269-80. PMID: 1279354.
    Citations: 7     Fields:    Translation:AnimalsCells
  120. Lee SW, Tomasetto C, Paul D, Keyomarsi K, Sager R. Transcriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell lines. J Cell Biol. 1992 Sep; 118(5):1213-21. PMID: 1324944.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  121. White TW, Bruzzone R, Goodenough DA, Paul DL. Mouse Cx50, a functional member of the connexin family of gap junction proteins, is the lens fiber protein MP70. Mol Biol Cell. 1992 Jul; 3(7):711-20. PMID: 1325220.
    Citations: 97     Fields:    Translation:AnimalsCells
  122. Haefliger JA, Bruzzone R, Jenkins NA, Gilbert DJ, Copeland NG, Paul DL. Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping. J Biol Chem. 1992 Jan 25; 267(3):2057-64. PMID: 1370487.
    Citations: 40     Fields:    Translation:AnimalsCells
  123. Paul DL, Ebihara L, Takemoto LJ, Swenson KI, Goodenough DA. Connexin46, a novel lens gap junction protein, induces voltage-gated currents in nonjunctional plasma membrane of Xenopus oocytes. J Cell Biol. 1991 Nov; 115(4):1077-89. PMID: 1659572.
    Citations: 190     Fields:    Translation:AnimalsCells
  124. Valdimarsson G, De Sousa PA, Beyer EC, Paul DL, Kidder GM. Zygotic expression of the connexin43 gene supplies subunits for gap junction assembly during mouse preimplantation development. Mol Reprod Dev. 1991 Sep; 30(1):18-26. PMID: 1664214.
    Citations: 8     Fields:    Translation:AnimalsCells
  125. Naus CC, Bechberger JF, Paul DL. Gap junction gene expression in human seizure disorder. Exp Neurol. 1991 Feb; 111(2):198-203. PMID: 1846600.
    Citations: 16     Fields:    Translation:HumansCells
  126. Swenson KI, Piwnica-Worms H, McNamee H, Paul DL. Tyrosine phosphorylation of the gap junction protein connexin43 is required for the pp60v-src-induced inhibition of communication. Cell Regul. 1990 Dec; 1(13):989-1002. PMID: 1966893.
    Citations: 70     Fields:    Translation:AnimalsCells
  127. Beyer EC, Paul DL, Goodenough DA. Connexin family of gap junction proteins. J Membr Biol. 1990 Jul; 116(3):187-94. PMID: 2167375.
    Citations: 102     Fields:    Translation:AnimalsCells
  128. Crow DS, Beyer EC, Paul DL, Kobe SS, Lau AF. Phosphorylation of connexin43 gap junction protein in uninfected and Rous sarcoma virus-transformed mammalian fibroblasts. Mol Cell Biol. 1990 Apr; 10(4):1754-63. PMID: 1690850.
    Citations: 93     Fields:    Translation:AnimalsCells
  129. Neveu MJ, Hully JR, Paul DL, Pitot HC. Reversible alteration in the expression of the gap junctional protein connexin 32 during tumor promotion in rat liver and its role during cell proliferation. Cancer Commun. 1990; 2(1):21-31. PMID: 1973356.
    Citations: 8     Fields:    Translation:Animals
  130. Stevenson BR, Paul DL. The molecular constituents of intercellular junctions. Curr Opin Cell Biol. 1989 Oct; 1(5):884-91. PMID: 2560659.
    Citations: 10     Fields:    Translation:AnimalsCells
  131. Swenson KI, Jordan JR, Beyer EC, Paul DL. Formation of gap junctions by expression of connexins in Xenopus oocyte pairs. Cell. 1989 Apr 07; 57(1):145-55. PMID: 2467743.
    Citations: 86     Fields:    Translation:AnimalsCells
  132. Ebihara L, Beyer EC, Swenson KI, Paul DL, Goodenough DA. Cloning and expression of a Xenopus embryonic gap junction protein. Science. 1989 Mar 03; 243(4895):1194-5. PMID: 2466337.
    Citations: 53     Fields:    Translation:AnimalsCells
  133. Beyer EC, Kistler J, Paul DL, Goodenough DA. Antisera directed against connexin43 peptides react with a 43-kD protein localized to gap junctions in myocardium and other tissues. J Cell Biol. 1989 Feb; 108(2):595-605. PMID: 2537319.
    Citations: 105     Fields:    Translation:AnimalsCells
  134. Barron DJ, Valdimarsson G, Paul DL, Kidder GM. Connexin32, a gap junction protein, is a persistent oogenetic product through preimplantation development of the mouse. Dev Genet. 1989; 10(4):318-23. PMID: 2551553.
    Citations: 4     Fields:    Translation:Animals
  135. Goodenough DA, Paul DL, Jesaitis L. Topological distribution of two connexin32 antigenic sites in intact and split rodent hepatocyte gap junctions. J Cell Biol. 1988 Nov; 107(5):1817-24. PMID: 2460469.
    Citations: 57     Fields:    Translation:AnimalsCells
  136. Beer DG, Neveu MJ, Paul DL, Rapp UR, Pitot HC. Expression of the c-raf protooncogene, gamma-glutamyltranspeptidase, and gap junction protein in rat liver neoplasms. Cancer Res. 1988 Mar 15; 48(6):1610-7. PMID: 2894242.
    Citations: 17     Fields:    Translation:AnimalsCells
  137. Beyer EC, Paul DL, Goodenough DA. Connexin43: a protein from rat heart homologous to a gap junction protein from liver. J Cell Biol. 1987 Dec; 105(6 Pt 1):2621-9. PMID: 2826492.
    Citations: 239     Fields:    Translation:AnimalsCells
  138. Dahl G, Miller T, Paul D, Voellmy R, Werner R. Expression of functional cell-cell channels from cloned rat liver gap junction complementary DNA. Science. 1987 Jun 05; 236(4806):1290-3. PMID: 3035715.
    Citations: 50     Fields:    Translation:AnimalsCells
  139. Traub O, Look J, Paul D, Willecke K. Cyclic adenosine monophosphate stimulates biosynthesis and phosphorylation of the 26 kDa gap junction protein in cultured mouse hepatocytes. Eur J Cell Biol. 1987 Feb; 43(1):48-54. PMID: 3032632.
    Citations: 36     Fields:    Translation:AnimalsCells
  140. Paul DL. Molecular cloning of cDNA for rat liver gap junction protein. J Cell Biol. 1986 Jul; 103(1):123-34. PMID: 3013898.
    Citations: 149     Fields:    Translation:AnimalsCells
  141. Paul DL, Goodenough DA. In vitro synthesis and membrane insertion of bovine MP26, an integral protein from lens fiber plasma membrane. J Cell Biol. 1983 Mar; 96(3):633-8. PMID: 6833374.
    Citations: 9     Fields:    Translation:AnimalsCells
  142. Paul DL, Goodenough DA. Preparation, characterization, and localization of antisera against bovine MP26, an integral protein from lens fiber plasma membrane. J Cell Biol. 1983 Mar; 96(3):625-32. PMID: 6339520.
    Citations: 39     Fields:    Translation:AnimalsCells
  143. Goodenough DA, Paul DL, Culbert KE. Correlative gap junction ultrastructure. Birth Defects Orig Artic Ser. 1978; 14(2):83-97. PMID: 346085.
    Citations: 4     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.