Harvard Catalyst Profiles

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Qian Yuan, Ph.D., M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K08DK068085 (YUAN, QIAN) Jul 1, 2004 - Jun 30, 2009
    Chemokin receptors and regulatory T cells in IBD
    Role: Principal Investigator
  2. F32HL009672 (YUAN, QIAN) Mar 22, 1997
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Martin VM, Virkud YV, Dahan E, Seay HL, Itzkovits D, Vlamakis H, Xavier R, Shreffler WG, Yuan Q, Yassour M. Longitudinal disease-associated gut microbiome differences in infants with food protein-induced allergic proctocolitis. Microbiome. 2022 09 23; 10(1):154. PMID: 36138438; PMCID: PMC9503280.
    Citations:    Fields:    Translation:Humans
  2. Hou J, Zhao R, Cai T, Beaulieu-Jones B, Seyok T, Dahal K, Yuan Q, Xiong X, Bonzel CL, Fox C, Christiani DC, Jemielita T, Liao KP, Liaw KL, Cai T. Temporal Trends in Clinical Evidence of 5-Year Survival Within Electronic Health Records Among Patients With Early-Stage Colon Cancer Managed With Laparoscopy-Assisted Colectomy vs Open Colectomy. JAMA Netw Open. 2022 06 01; 5(6):e2218371. PMID: 35737384; PMCID: PMC9227003.
    Citations:    Fields:    Translation:Humans
  3. Seay HL, Martin VM, Virkud YV, Marget M, Shreffler WG, Yuan Q. Prospective associations between acid suppressive therapy and food allergy in early childhood. Clin Exp Allergy. 2022 05; 52(5):711-714. PMID: 35285103; PMCID: PMC9248370.
    Citations:    Fields:    Translation:Humans
  4. Martin VM, Marget M, Yuan Q, Shreffler WG. In response to Frequency of guideline-defined cow's milk allergy symptoms in infants: Secondary analysis of EAT trial data by Vincent et al. Clin Exp Allergy. 2022 Apr; 52(4):581-582. PMID: 34981585; PMCID: PMC9274452.
    Citations:    Fields:    
  5. Yuan Q, Du M, Loehrer E, Johnson BE, Gainor JF, Lanuti M, Li Y, Christiani DC. Postdiagnosis BMI Change Is Associated with Non-Small Cell Lung Cancer Survival. Cancer Epidemiol Biomarkers Prev. 2022 01; 31(1):262-268. PMID: 34728470; PMCID: PMC8755617.
    Citations:    Fields:    Translation:Humans
  6. Morgan DM, Ruiter B, Smith NP, Tu AA, Monian B, Stone BE, Virk-Hundal N, Yuan Q, Shreffler WG, Love JC. Clonally expanded, GPR15-expressing pathogenic effector TH2 cells are associated with eosinophilic esophagitis. Sci Immunol. 2021 08 13; 6(62). PMID: 34389613; PMCID: PMC8686696.
    Citations: 4     Fields:    Translation:HumansCells
  7. Bao WQ, Zi H, Yuan QQ, Li LY, Deng T. Global burden of thyroid cancer and its attributable risk factors in 204 countries and territories from 1990 to 2019. Thorac Cancer. 2021 09; 12(18):2494-2503. PMID: 34355519; PMCID: PMC8447914.
    Citations: 1     Fields:    Translation:Humans
  8. Yuan Q, Cai T, Hong C, Du M, Johnson BE, Lanuti M, Cai T, Christiani DC. Performance of a Machine Learning Algorithm Using Electronic Health Record Data to Identify and Estimate Survival in a Longitudinal Cohort of Patients With Lung Cancer. JAMA Netw Open. 2021 07 01; 4(7):e2114723. PMID: 34232304.
    Citations: 5     Fields:    Translation:Humans
  9. Du M, Garcia JGN, Christie JD, Xin J, Cai G, Meyer NJ, Zhu Z, Yuan Q, Zhang Z, Su L, Shen S, Dong X, Li H, Hutchinson JN, Tejera P, Lin X, Wang M, Chen F, Christiani DC. Integrative omics provide biological and clinical insights into acute respiratory distress syndrome. Intensive Care Med. 2021 07; 47(7):761-771. PMID: 34032881; PMCID: PMC8144871.
    Citations: 4     Fields:    Translation:HumansCells
  10. Lains I, Zhu S, Han X, Chung W, Yuan Q, Kelly RS, Gil JQ, Katz R, Nigalye A, Kim IK, Miller JB, Carreira IM, Silva R, Vavvas DG, Miller JW, Lasky-Su J, Liang L, Husain D. Genomic-Metabolomic Associations Support the Role of LIPC and Glycerophospholipids in Age-Related Macular Degeneration. Ophthalmol Sci. 2021 Mar; 1(1). PMID: 34382031; PMCID: PMC8353724.
    Citations: 3     
  11. Wang Z, Du M, Yuan Q, Guo Y, Hutchinson JN, Su L, Zheng Y, Wang J, Mucci LA, Lin X, Hou L, Christiani DC. Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers. Neoplasia. 2020 03; 22(3):154-161. PMID: 32062069.
    Citations: 5     Fields:    Translation:HumansCells
  12. Su KW, Patil SU, Stockbridge JL, Martin VM, Virkud YV, Huang JL, Shreffler WG, Yuan Q. Food aversion and poor weight gain in food protein-induced enterocolitis syndrome: A retrospective study. J Allergy Clin Immunol. 2020 05; 145(5):1430-1437.e11. PMID: 31940468; PMCID: PMC8360679.
    Citations: 4     Fields:    Translation:HumansAnimals
  13. Martin VM, Virkud YV, Seay H, Hickey A, Ndahayo R, Rosow R, Southwick C, Elkort M, Gupta B, Kramer E, Pronchick T, Reuter S, Keet C, Su KW, Shreffler WG, Yuan Q. Prospective Assessment of Pediatrician-Diagnosed Food Protein-Induced Allergic Proctocolitis by Gross or Occult Blood. J Allergy Clin Immunol Pract. 2020 05; 8(5):1692-1699.e1. PMID: 31917366; PMCID: PMC8403015.
    Citations: 12     Fields:    Translation:HumansAnimals
  14. Zhao JL, Du ZY, Sun YR, Yuan Q, Yu J, Wu X, Li ZQ, Wu XH, Xie R, Hu J. Intensive blood pressure control reduces the risk of progressive hemorrhage in patients with acute hypertensive intracerebral hemorrhage: A retrospective observational study. Clin Neurol Neurosurg. 2019 05; 180:1-6. PMID: 30870760.
    Citations: 6     Fields:    Translation:Humans
  15. Kang D, Do D, Ryu J, Grant CN, Giddings SL, Rosenberg M, Hesterberg PE, Yuan Q, Garber JJ, Katz AJ, Tearney GJ. A miniaturized, tethered, spectrally-encoded confocal endomicroscopy capsule. Lasers Surg Med. 2019 Jan 06. PMID: 30614021.
    Citations: 4     Fields:    
  16. Martin V, Keet C, Yuan Q. Antibiotics and Acid-Suppressing Medications in Early Life and Allergic Disorders. JAMA Pediatr. 2018 10 01; 172(10):989-990. PMID: 30128574.
    Citations: 2     Fields:    Translation:Humans
  17. Martin VJ, Shreffler WG, Yuan Q. Presumed Allergic Proctocolitis Resolves with Probiotic Monotherapy: A Report of 4 Cases. Am J Case Rep. 2016 Aug 29; 17:621-4. PMID: 27568925.
    Citations: 4     Fields:    Translation:HumansCells
  18. Leung J, Mehrzad R, Hundal NV, Alejos A, Hesterberg PE, Katz AJ, Yuan Q, Shreffler WG. Longitudinal Perspective on Managing Refractory Eosinophilic Esophagitis. J Allergy Clin Immunol Pract. 2015 Nov-Dec; 3(6):951-6. PMID: 26342740.
    Citations: 8     Fields:    Translation:Humans
  19. Radano MC, Yuan Q, Katz A, Fleming JT, Kubala S, Shreffler W, Keet CA. Cesarean section and antibiotic use found to be associated with eosinophilic esophagitis. J Allergy Clin Immunol Pract. 2014 Jul-Aug; 2(4):475-477.e1. PMID: 25017541.
    Citations: 28     Fields:    Translation:HumansPHPublic Health
  20. Tabatabaei N, Kang D, Wu T, Kim M, Carruth RW, Leung J, Sauk JS, Shreffler W, Yuan Q, Katz A, Nishioka NS, Tearney GJ. Tethered confocal endomicroscopy capsule for diagnosis and monitoring of eosinophilic esophagitis. Biomed Opt Express. 2013 Dec 13; 5(1):197-207. PMID: 24466487.
    Citations: 18     
  21. Leung J, Hundal NV, Katz AJ, Shreffler WG, Yuan Q, Butterworth CA, Hesterberg PE. Tolerance of baked milk in patients with cow's milk-mediated eosinophilic esophagitis. J Allergy Clin Immunol. 2013 Nov; 132(5):1215-1216.e1. PMID: 24084076; PMCID: PMC5035707.
    Citations: 19     Fields:    Translation:HumansAnimals
  22. Iyengar SR, Ebb DH, Yuan Q, Shailam R, Bhan AK. Case records of the Massachusetts General Hospital. Case 27-2013. A 6.5-month-old boy with fever, rash, and cytopenias. N Engl J Med. 2013 Aug 29; 369(9):853-63. PMID: 23984733.
    Citations: 2     Fields:    Translation:Humans
  23. Katz A, Virk Hundal N, Yuan Q, Shreffler W. Cow's milk allergy: a new approach needed? J Pediatr. 2013 Sep; 163(3):620-2. PMID: 23809049.
    Citations: 2     Fields:    Translation:Humans
  24. Benor S, Russell GH, Silver M, Israel EJ, Yuan Q, Winter HS. Shortcomings of the inflammatory bowel disease Serology 7 panel. Pediatrics. 2010 Jun; 125(6):1230-6. PMID: 20439597.
    Citations: 17     Fields:    Translation:Humans
  25. Yuan Q, Bromley SK, Means TK, Jones KJ, Hayashi F, Bhan AK, Luster AD. CCR4-dependent regulatory T cell function in inflammatory bowel disease. J Exp Med. 2007 Jun 11; 204(6):1327-34. PMID: 17548518; PMCID: PMC2118617.
    Citations: 54     Fields:    Translation:AnimalsCells
  26. Yuan Q, Winter HS. Pediatric and Adolescent GERD. Current GERD Reports. 2007; In press.
  27. Yuan Q, Campanella GS, Colvin RA, Hamilos DL, Jones KJ, Mathew A, Means TK, Luster AD. Membrane-bound eotaxin-3 mediates eosinophil transepithelial migration in IL-4-stimulated epithelial cells. Eur J Immunol. 2006 Oct; 36(10):2700-14. PMID: 16983721.
    Citations: 20     Fields:    Translation:HumansCells
  28. Heller EA, Liu E, Tager AM, Yuan Q, Lin AY, Ahluwalia N, Jones K, Koehn SL, Lok VM, Aikawa E, Moore KJ, Luster AD, Gerszten RE. Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells. Circulation. 2006 May 16; 113(19):2301-12. PMID: 16682613.
    Citations: 102     Fields:    Translation:AnimalsCells
  29. Yuan Q, Bousvaros A. Gastrointestinal Manifestations of Primary Immunodeficiencies. Pediatric Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/ Management. Ed. Wyllie and Hyams. 2006; 601-616.
  30. Yuan Q, Walker WA. Worm therapy for ulcerative colitis: a possible link to regulatory T cells. J Pediatr Gastroenterol Nutr. 2005 Jul; 41(1):139-40. PMID: 15990650.
    Citations:    Fields:    Translation:HumansAnimalsCells
  31. Yuan Q, Walker WA. Innate immunity of the gut: mucosal defense in health and disease. J Pediatr Gastroenterol Nutr. 2004 May; 38(5):463-73. PMID: 15097431.
    Citations: 21     Fields:    Translation:Humans
  32. Yuan Q, Winter HS. Crohn's Disease. Textbook of Pediatric Gastroenerology and Nutrition. Ed. Guandalini. 2004; 347-378.
  33. Yuan Q, Jonas MM. Pediatric hepatobiliary disease. Curr Opin Gastroenterol. 2003 May; 19(3):276-80. PMID: 15703569.
    Citations:    Fields:    
  34. Yuan Q, Winter HS. Gastroesophagus Reflux Disease in Children. GERD/Dyspepsia. Ed. Fass. 2003; 259-261.
  35. Yuan Q, Furuta GT. Selective Summary. Insight of milk protein allergy: microenvironment matters. Gastroenterology. 2003; 124:259-261.
  36. Yuan Q, Pappa H, Russell GJ. Gastroesophageal Reflux. Current Pediatric Therapy. Eds. Burg, Ingelfinger, Polin and Gershon. 2002; 583-585.
  37. Ochi H, Hirani WM, Yuan Q, Friend DS, Austen KF, Boyce JA. T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro. J Exp Med. 1999 Jul 19; 190(2):267-80. PMID: 10432289; PMCID: PMC2195573.
    Citations: 77     Fields:    Translation:HumansCells
  38. Yuan Q, Gurish MF, Friend DS, Austen KF, Boyce JA. Generation of a novel stem cell factor-dependent mast cell progenitor. J Immunol. 1998 Nov 15; 161(10):5143-6. PMID: 9820483.
    Citations: 13     Fields:    Translation:AnimalsCells
  39. Yuan Q, Austen KF, Friend DS, Heidtman M, Boyce JA. Human peripheral blood eosinophils express a functional c-kit receptor for stem cell factor that stimulates very late antigen 4 (VLA-4)-mediated cell adhesion to fibronectin and vascular cell adhesion molecule 1 (VCAM-1). J Exp Med. 1997 Jul 21; 186(2):313-23. PMID: 9221761; PMCID: PMC2198988.
    Citations: 21     Fields:    Translation:HumansCells
  40. Yuan Q, Strauch KL, Lobb RR, Hemler ME. Intracellular single-chain antibody inhibits integrin VLA-4 maturation and function. Biochem J. 1996 Sep 01; 318 ( Pt 2):591-6. PMID: 8809051; PMCID: PMC1217661.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  41. Leung E, Mead PE, Yuan Q, Jiang WM, Watson JD, Krissansen GW. The mouse beta 7 integrin gene promoter: transcriptional regulation of the leukocyte integrins LPAM-1 and M290. Int Immunol. 1993 May; 5(5):551-8. PMID: 8318458.
    Citations: 2     Fields:    Translation:AnimalsCells
  42. Jiang WM, Jenkins D, Yuan Q, Leung E, Choo KH, Watson JD, Krissansen GW. The gene organization of the human beta 7 subunit, the common beta subunit of the leukocyte integrins HML-1 and LPAM-1. Int Immunol. 1992 Sep; 4(9):1031-40. PMID: 1382574.
    Citations: 5     Fields:    Translation:HumansCells
  43. Yuan Q, Jiang WM, Leung E, Hollander D, Watson JD, Krissansen GW. Molecular cloning of the mouse integrin beta 7 subunit. J Biol Chem. 1992 Apr 15; 267(11):7352-8. PMID: 1559978.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  44. Krissansen GW, Print CG, Prestidge RL, Hollander D, Yuan Q, Jiang WM, Jenkins DR, Leung E, Mead P, Yong R, et al. Immunologic and structural relatedness of the integrin beta 7 complex and the human intraepithelial lymphocyte antigen HML-1. FEBS Lett. 1992 Jan 13; 296(1):25-8. PMID: 1730287.
    Citations: 2     Fields:    Translation:HumansCells
  45. Krissansen GW, Yuan Q, Jenkins D, Jiang WM, Rooke L, Spurr NK, Eccles M, Leung E, Watson JD. Chromosomal locations of the genes coding for the integrin beta 6 and beta 7 subunits. Immunogenetics. 1992; 35(1):58-61. PMID: 1729173.
    Citations: 4     Fields:    Translation:Humans
  46. Baker E, Sutherland GR, Jiang WM, Yuan Q, Leung E, Watson JD, Krissansen GW. Mapping of the human integrin beta 7 gene (ITG beta 7) to 12q13.13 by non-isotopic in situ hybridization. Mamm Genome. 1992; 2(4):272-3. PMID: 1543919.
    Citations: 3     Fields:    Translation:HumansCells
  47. Yuan Q, Kozak CA, Jiang WM, Hollander D, Watson JD, Krissansen GW. Genetic mapping of the gene coding for the integrin beta 7 subunit to the distal part of mouse chromosome 15. Immunogenetics. 1992; 35(6):403-7. PMID: 1349587.
    Citations: 1     Fields:    Translation:AnimalsCells
  48. Yuan Q, Jiang WM, Hollander D, Leung E, Watson JD, Krissansen GW. Identity between the novel integrin beta 7 subunit and an antigen found highly expressed on intraepithelial lymphocytes in the small intestine. Biochem Biophys Res Commun. 1991 May 15; 176(3):1443-9. PMID: 1710115.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  49. Yuan QA, Jiang WM, Krissansen GW, Watson JD. Cloning and sequence analysis of a novel beta 2-related integrin transcript from T lymphocytes: homology of integrin cysteine-rich repeats to domain III of laminin B chains. Int Immunol. 1990; 2(11):1097-108. PMID: 2083230.
    Citations: 27     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.