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Rachel Lee Rosen, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK097112 (ROSEN, RACHEL L) Jul 1, 2015 - May 31, 2020
    NIH/NIDDK
    Gastrointestinal Microflora Changes in Children Treated with Proton Pump Inhibitors
    Role: Principal Investigator
  2. R03DK089146 (ROSEN, RACHEL L) Jul 1, 2010 - Dec 31, 2013
    NIH/NIDDK
    Microaspiration as a cause for respiratory disease in children
    Role: Principal Investigator
  3. K23DK073713 (ROSEN, RACHEL L) Feb 1, 2007 - Jan 31, 2013
    NIH/NIDDK
    Impact of non-acid reflux on respiratory diseases in children
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Duncan DR, Larson K, Rosen RL. Clinical Aspects of Thickeners for Pediatric Gastroesophageal Reflux and Oropharyngeal Dysphagia. Curr Gastroenterol Rep. 2019 May 16; 21(7):30. PMID: 31098722.
    Citations:    
  2. Duncan DR, Growdon AS, Liu E, Larson K, Gonzalez M, Norris K, Rosen RL. The Impact of the American Academy of Pediatrics Brief Resolved Unexplained Event Guidelines on Gastrointestinal Testing and Prescribing Practices. J Pediatr. 2019 May 15. PMID: 31103259.
    Citations:    
  3. Duncan DR, Larson K, Davidson K, May K, Rahbar R, Rosen RL. Feeding Interventions Are Associated With Improved Outcomes in Children With Laryngeal Penetration. J Pediatr Gastroenterol Nutr. 2019 Feb; 68(2):218-224. PMID: 30320668.
    Citations:    Fields:    
  4. Duncan DR, Mitchell PD, Larson K, McSweeney ME, Rosen RL. Association of Proton Pump Inhibitors With Hospitalization Risk in Children With Oropharyngeal Dysphagia. JAMA Otolaryngol Head Neck Surg. 2018 Oct 11. PMID: 30325987.
    Citations:    Fields:    
  5. Rubinstein E, Rosen RL. Respiratory symptoms associated with eosinophilic esophagitis. Pediatr Pulmonol. 2018 11; 53(11):1587-1591. PMID: 30238702.
    Citations:    Fields:    
  6. Duncan DR, Mitchell PD, Larson K, Rosen RL. Presenting Signs and Symptoms do not Predict Aspiration Risk in Children. J Pediatr. 2018 10; 201:141-146. PMID: 29960768.
    Citations:    Fields:    
  7. McSweeney ME, Kerr J, Amirault J, Fishman E, Lurie M, Peinado-Fabregat MI, Mitchell PD, Rosen R. Preoperative Evaluation Is Not Predictive of Transpyloric Feeding Conversion in Gastrostomy-dependent Pediatric Patients. J Pediatr Gastroenterol Nutr. 2018 Jun; 66(6):887-892. PMID: 29261527.
    Citations:    Fields:    
  8. Rosen RL, Krishnan U, Mousa H, Dall'oglio L, Faure C, Gottrand F. The Case for Thoughtful Prescribing of Proton Pump Inhibitors in Infants. J Pediatr Gastroenterol Nutr. 2018 01; 66(1):e26-e27. PMID: 29045354.
    Citations:    Fields:    
  9. Duncan DR, Amirault J, Mitchell PD, Larson K, Rosen RL. Oropharyngeal Dysphagia Is Strongly Correlated With Apparent Life-Threatening Events. J Pediatr Gastroenterol Nutr. 2017 08; 65(2):168-172. PMID: 27741062.
    Citations: 2     Fields:    Translation:Humans
  10. Rosen R, Mitchell PD, Amirault J, Amin M, Watters K, Rahbar R. The Edematous and Erythematous Airway Does Not Denote Pathologic Gastroesophageal Reflux. J Pediatr. 2017 04; 183:127-131. PMID: 27979581.
    Citations: 1     Fields:    Translation:Humans
  11. Duncan DR, Amirault J, Johnston N, Mitchell P, Larson K, Rosen RL. Gastroesophageal Reflux Burden, Even in Children That Aspirate, Does Not Increase Pediatric Hospitalization. J Pediatr Gastroenterol Nutr. 2016 08; 63(2):210-7. PMID: 26794490.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  12. Dy F, Amirault J, Mitchell PD, Rosen R. Salivary Pepsin Lacks Sensitivity as a Diagnostic Tool to Evaluate Extraesophageal Reflux Disease. J Pediatr. 2016 10; 177:53-58. PMID: 27453366.
    Citations: 2     Fields:    Translation:Humans
  13. Johnston N, Ondrey F, Rosen R, Hurley BP, Gould J, Allen J, DelGaudio J, Altman KW. Airway reflux. Ann N Y Acad Sci. 2016 10; 1381(1):5-13. PMID: 27310222.
    Citations: 2     Fields:    Translation:HumansAnimals
  14. Ganesh M, Hertzberg A, Nurko S, Needleman H, Rosen R. Acid Rather Than Nonacid Reflux Burden Is a Predictor of Tooth Erosion. J Pediatr Gastroenterol Nutr. 2016 Feb; 62(2):309-13. PMID: 26230904.
    Citations: 1     Fields:    Translation:Humans
  15. McSweeney ME, Kerr J, Amirault J, Mitchell PD, Larson K, Rosen R. Oral Feeding Reduces Hospitalizations Compared with Gastrostomy Feeding in Infants and Children Who Aspirate. J Pediatr. 2016 Mar; 170:79-84. PMID: 26687714.
    Citations: 2     Fields:    Translation:Humans
  16. Mahoney L, Rosen R. Feeding Difficulties in Children with Esophageal Atresia. Paediatr Respir Rev. 2016 Jun; 19:21-7. PMID: 26164203.
    Citations: 3     Fields:    Translation:Humans
  17. Rosen R, Hu L, Amirault J, Khatwa U, Ward DV, Onderdonk A. 16S community profiling identifies proton pump inhibitor related differences in gastric, lung, and oropharyngeal microflora. J Pediatr. 2015 Apr; 166(4):917-23. PMID: 25661411.
    Citations: 10     Fields:    Translation:HumansCells
  18. Rosen R, Amirault J, Liu H, Mitchell P, Hu L, Khatwa U, Onderdonk A. Changes in gastric and lung microflora with acid suppression: acid suppression and bacterial growth. JAMA Pediatr. 2014 Oct; 168(10):932-7. PMID: 25133779.
    Citations: 17     Fields:    Translation:Humans
  19. Rosen R, Amirault J, Heinz N, Litman H, Khatwa U. The sensitivity of acoustic cough recording relative to intraesophageal pressure recording and patient report during reflux testing. Neurogastroenterol Motil. 2014 Nov; 26(11):1635-41. PMID: 25264213.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  20. Rosen R. Gastroesophageal reflux in infants: more than just a pHenomenon. JAMA Pediatr. 2014 Jan; 168(1):83-9. PMID: 24276411.
    Citations: 2     Fields:    Translation:Humans
  21. Rosen R, Amirault J, Giligan E, Khatwa U, Nurko S. Intraesophageal pressure recording improves the detection of cough during multichannel intraluminal impedance testing in children. J Pediatr Gastroenterol Nutr. 2014 Jan; 58(1):22-6. PMID: 23942006.
    Citations: 5     Fields:    Translation:Humans
  22. Palm K, Sawicki G, Rosen R. The impact of reflux burden on Pseudomonas positivity in children with cystic fibrosis. Pediatr Pulmonol. 2012 Jun; 47(6):582-7. PMID: 22162484.
    Citations: 12     Fields:    Translation:HumansCells
  23. Rosen R, Johnston N, Hart K, Khatwa U, Nurko S. The presence of pepsin in the lung and its relationship to pathologic gastro-esophageal reflux. Neurogastroenterol Motil. 2012 Feb; 24(2):129-33, e84-5. PMID: 22141343.
    Citations: 7     Fields:    Translation:Humans
  24. Loots CM, van Wijk MP, Blondeau K, Dalby K, Peeters L, Rosen R, Salvatore S, Wenzl TG, Vandenplas Y, Benninga MA, Omari TI. Interobserver and intraobserver variability in pH-impedance analysis between 10 experts and automated analysis. J Pediatr. 2012 Mar; 160(3):441-446.e1. PMID: 21924738.
    Citations: 10     Fields:    Translation:Humans
  25. Rosen R, Johnston N, Hart K, Khatwa U, Katz E, Nurko S. Higher rate of bronchoalveolar lavage culture positivity in children with nonacid reflux and respiratory disorders. J Pediatr. 2011 Sep; 159(3):504-6. PMID: 21777922.
    Citations: 4     Fields:    Translation:Humans
  26. Rosen R, Hart K, Warlaumont M. Incidence of gastroesophageal reflux during transpyloric feeds. J Pediatr Gastroenterol Nutr. 2011 May; 52(5):532-5. PMID: 21464758.
    Citations: 3     Fields:    Translation:Humans
  27. Rosen R, Hart K, Nurko S. Does reflux monitoring with multichannel intraluminal impedance change clinical decision making? J Pediatr Gastroenterol Nutr. 2011 Apr; 52(4):404-7. PMID: 21407105.
    Citations: 4     Fields:    Translation:Humans
  28. Chiou E, Rosen R, Nurko S. Effect of different pH criteria on dual-sensor pH monitoring in the evaluation of supraesophageal gastric reflux in children. J Pediatr Gastroenterol Nutr. 2011 Apr; 52(4):399-403. PMID: 21206381.
    Citations: 4     Fields:    Translation:Humans
  29. Mousa HM, Rosen R, Woodley FW, Orsi M, Armas D, Faure C, Fortunato J, O'connor J, Skaggs B, Nurko S. Esophageal impedance monitoring for gastroesophageal reflux. J Pediatr Gastroenterol Nutr. 2011 Feb; 52(2):129-39. PMID: 21240010.
    Citations: 19     Fields:    Translation:Humans
  30. Rosen R, Levine P, Lewis J, Mitchell P, Nurko S. Reflux events detected by pH-MII do not determine fundoplication outcome. J Pediatr Gastroenterol Nutr. 2010 Mar; 50(3):251-5. PMID: 20118804.
    Citations: 14     Fields:    Translation:Humans
  31. Nurko S, Rosen R, Furuta GT. Esophageal dysmotility in children with eosinophilic esophagitis: a study using prolonged esophageal manometry. Am J Gastroenterol. 2009 Dec; 104(12):3050-7. PMID: 19755968.
    Citations: 18     Fields:    Translation:Humans
  32. Rahbar R, Chen JL, Rosen RL, Lowry KC, Simon DM, Perez JA, Buonomo C, Ferrari LR, Katz ES. Endoscopic repair of laryngeal cleft type I and type II: when and why? Laryngoscope. 2009 Sep; 119(9):1797-802. PMID: 19554639.
    Citations: 4     Fields:    Translation:Humans
  33. Rosen R, Furuta G, Fritz J, Donovan K, Nurko S. Role of acid and nonacid reflux in children with eosinophilic esophagitis compared with patients with gastroesophageal reflux and control patients. J Pediatr Gastroenterol Nutr. 2008 May; 46(5):520-3. PMID: 18493206.
    Citations: 9     Fields:    Translation:Humans
  34. Rosen R, Fritz J, Nurko A, Simon D, Nurko S. Lipid-laden macrophage index is not an indicator of gastroesophageal reflux-related respiratory disease in children. Pediatrics. 2008 Apr; 121(4):e879-84. PMID: 18362101.
    Citations: 7     Fields:    Translation:HumansCells
  35. Nurko S, Rosen R. Esophageal dysmotility in patients who have eosinophilic esophagitis. Gastrointest Endosc Clin N Am. 2008 Jan; 18(1):73-89; ix. PMID: 18061103.
    Citations: 16     Fields:    Translation:HumansCells
  36. Rosen R, Lord C, Nurko S. The sensitivity of multichannel intraluminal impedance and the pH probe in the evaluation of gastroesophageal reflux in children. Clin Gastroenterol Hepatol. 2006 Feb; 4(2):167-72. PMID: 16469676.
    Citations: 22     Fields:    Translation:Humans
  37. Nurko S, Rosen R. Use of multi-channel intraluminal impedance (MII) in the evaluation of children with respiratory symptoms: a new phenomenon? J Pediatr Gastroenterol Nutr. 2005 Aug; 41(2):166-8. PMID: 16056094.
    Citations:    Fields:    Translation:Humans
  38. Rosen R, Nurko S. The importance of multichannel intraluminal impedance in the evaluation of children with persistent respiratory symptoms. Am J Gastroenterol. 2004 Dec; 99(12):2452-8. PMID: 15571595.
    Citations: 37     Fields:    Translation:Humans
  39. Rosen R, Buonomo C, Andrade R, Nurko S. Incidence of spinal cord lesions in patients with intractable constipation. J Pediatr. 2004 Sep; 145(3):409-11. PMID: 15343201.
    Citations: 6     Fields:    Translation:Humans
  40. Rosen R, Nurko S, Furuta GT. Impeding gastroesophageal refluxate: a new application of an old medication. Gastroenterology. 2003 Sep; 125(3):984-5; discussion 985-6. PMID: 12949747.
    Citations: 1     Fields:    Translation:Humans
  41. Rosen R, Integlia MJ, Bousvaros A. Severe pancytopenia from thiopurine methyltransferase deficiency: a preventable complication of 6-mercaptopurine therapy in children with Crohn disease. J Pediatr Gastroenterol Nutr. 2002 Nov; 35(5):695-9. PMID: 12454589.
    Citations: 2     Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.