Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Matthias Nahrendorf, M.D.

Profile Picture

University of Heidelberg , GermanyMD04/1998Medicine
Harvard Medical School, Boston, USAM. Sc. 04/217(Hon)
Martin Research Prize
Rolf Sammet Guest Professor, Frankfurt University
Endowed Chair, MGH Research Institute
Adjunct Professor of Medicine, Julius-Maximilians-Universität Würzburg
Appointed to NHLBI board of external experts
Chair Atherosclerosis Gordon Research Conference
Basic Research Award, German Society of Cardiology
MGH Research Scholar Award
Member, American Society of Clinical Investigation

The Nahrendorf laboratory focuses on the role of immunity in cardiovascular health and disease, specifically in atherosclerosis and heart failure. Of particular interest are the function, supply and production of leukocytes, and the signals that regulate hematopoiesis after injuries such as myocardial infarction or stroke. We described that after MI, the spleen releases a large population of ready-made leukocytes that travel to the ischemic heart (Science 2009, New York Times 2009). We further found that MI, chronic stress and sedentary life style modulate the hematopoietic stem cell niche, activating migration and proliferation of myeloid progenitor cells (Nature 2012, Nature Med 2014, Nature Med 2019). Resident macrophages, on the other hand, do not derive from circulating cells and promote steady state functions such as cardiac conduction (Cell 2017). The laboratory also develops and employs imaging to sample biology non-invasively, using MR, nuclear, optical and microscopic modalities.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P01HL142494 (NAHRENDORF, MATTHIAS) Aug 1, 2019 - Jul 31, 2024
    Hematopoiesis in cardiovascular disease
    Role: Principal Investigator
  2. R01NS108419 (MOSKOWITZ, MICHAEL A. ;NAHRENDORF, MATTHIAS) Sep 30, 2018 - Jul 31, 2024
    Skull marrow crosstalk with the central nervous system
    Role: Co-Principal Investigator
  3. R35HL139598 (NAHRENDORF, MATTHIAS) Feb 1, 2018 - Jan 31, 2025
    Imaging organ system interfaces in ischemic heart disease
    Role: Principal Investigator
  4. R13HL137211 (NAHRENDORF, MATTHIAS) May 1, 2017 - Apr 30, 2018
    2017 Atherosclerosis Gordon Research Conference & Gordon Research Seminar
    Role: Principal Investigator
  5. R01HL131495 (NAHRENDORF, MATTHIAS) Feb 1, 2017 - Jan 31, 2021
    Quantitative nanoparticle imaging of macrophages
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
This operation might take several minutes to complete. Please do not close your browser.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Nahrendorf's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (774)
Co-Authors (142)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.