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Joseph Moeketsi Makhema, M.B.,B.S.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Caniglia EC, Zash R, Swanson SA, Wirth KE, Diseko M, Mayondi G, Lockman S, Mmalane M, Makhema J, Dryden-Peterson S, Kponee-Shovein KZ, John O, Murray EJ, Shapiro RL. Methodological Challenges When Studying Distance to Care as an Exposure in Health Research. Am J Epidemiol. 2019 May 20. PMID: 31107529.
    Citations:    
  2. Moyo S, Gaseitsiwe S, Zahralban-Steele M, Maruapula D, Nkhisang T, Mokaleng B, Mohammed T, Ditlhako TR, Bareng OT, Mokgethi TP, van Widenfelt E, Pretorius-Holme M, Mine MO, Raizes E, Yankinda EK, Wirth KE, Gaolathe T, Makhema JM, Lockman S, Essex M, Novitsky V. Low rates of nucleoside reverse transcriptase inhibitor and nonnucleoside reverse transcriptase inhibitor drug resistance in Botswana. AIDS. 2019 May 01; 33(6):1073-1082. PMID: 30946161.
    Citations:    
  3. Shava E, Moyo S, Zash R, Diseko M, Dintwa EN, Mupfumi L, Mabuta J, Mayondi G, Chen JY, Lockman S, Mmalane M, Makhema J, Shapiro R. High rates of adverse birth outcomes in HIV and syphilis co-infected women in Botswana. J Acquir Immune Defic Syndr. 2019 Apr 29. PMID: 31107303.
    Citations:    
  4. Cassidy AR, Williams PL, Leidner J, Mayondi G, Ajibola G, Makhema J, Holding PA, Powis KM, Batlang O, Petlo C, Shapiro R, Kammerer B, Lockman S. In Utero Efavirenz Exposure and Neurodevelopmental Outcomes in HIV-exposed Uninfected Children in Botswana. Pediatr Infect Dis J. 2019 Apr 10. PMID: 30985518.
    Citations:    
  5. Moyo S, Gaseitsiwe S, Zahralban-Steele M, Maruapula D, Nkhisang T, Mokaleng B, Mohammed T, Ditlhako TR, Bareng OT, Mokgethi TP, van Widenfelt E, Pretorius-Holme M, Mine MO, Raizes E, Yankinda EK, Wirth KE, Gaolathe T, Makhema JM, Lockman S, Essex M, Novitsky V. Low rates of NRTI and NNRTI drug resistance among participants in the Botswana combination prevention program (BCPP) trial. AIDS. 2019 Feb 07. PMID: 30741821.
    Citations:    
  6. Rose R, Hall M, Redd AD, Lamers S, Barbier AE, Porcella SF, Hudelson SE, Piwowar-Manning E, McCauley M, Gamble T, Wilson EA, Kumwenda J, Hosseinipour MC, Hakim JG, Kumarasamy N, Chariyalertsak S, Pilotto JH, Grinsztejn B, Mills LA, Makhema J, Santos BR, Chen YQ, Quinn TC, Fraser C, Cohen MS, Eshleman SH, Laeyendecker O. Phylogenetic methods inconsistently predict direction of HIV transmission among heterosexual pairs in the HPTN052 cohort. J Infect Dis. 2018 Dec 24. PMID: 30590741.
    Citations:    Fields:    
  7. Kacanek D, Williams PL, Mayondi G, Holding P, Leidner J, Moabi K, Tepper V, Nichols S, Makhema J, Jibril H, Madidimalo T, Shapiro R, Lockman S, Kammerer B. Pediatric Neurodevelopmental Functioning After In Utero Exposure to Triple-NRTI vs. Dual-NRTI + PI ART in a Randomized Trial, Botswana. J Acquir Immune Defic Syndr. 2018 Nov 01; 79(3):e93-e100. PMID: 30015793.
    Citations:    Fields:    
  8. Moyo S, Gaseitsiwe S, Mohammed T, Pretorius Holme M, Wang R, Kotokwe KP, Boleo C, Mupfumi L, Yankinda EK, Chakalisa U, van Widenfelt E, Gaolathe T, Mmalane MO, Dryden-Peterson S, Mine M, Lebelonyane R, Bennett K, Leidner J, Wirth KE, Tchetgen Tchetgen E, Powis K, Moore J, Clarke WA, Lockman S, Makhema JM, Essex M, Novitsky V. Cross-sectional estimates revealed high HIV incidence in Botswana rural communities in the era of successful ART scale-up in 2013-2015. PLoS One. 2018; 13(10):e0204840. PMID: 30356287.
    Citations:    Fields:    
  9. Anderson M, Choga WT, Moyo S, Bell TG, Mbangiwa T, Phinius BB, Bhebhe L, Sebunya TK, Makhema J, Marlink R, Kramvis A, Essex M, Musonda RM, Blackard JT, Gaseitsiwe S. In Silico Analysis of Hepatitis B Virus Occult Associated Mutations in Botswana Using a Novel Algorithm. Genes (Basel). 2018 Aug 21; 9(9). PMID: 30134551.
    Citations:    
  10. Zash R, Rough K, Jacobson DL, Diseko M, Mayondi G, Mmalane M, Essex M, Petlo C, Lockman S, Makhema J, Shapiro RL. Effect of Gestational Age at Tenofovir-Emtricitabine-Efavirenz Initiation on Adverse Birth Outcomes in Botswana. J Pediatric Infect Dis Soc. 2018 Aug 17; 7(3):e148-e151. PMID: 29688554.
    Citations:    Fields:    Translation:Humans
  11. Novitsky V, Gaolathe T, Mmalane M, Moyo S, Chakalisa U, Yankinda EK, Marukutira T, Holme MP, Sekoto T, Gaseitsiwe S, Musonda R, van Widenfelt E, Powis KM, Khan N, Dryden-Peterson S, Bennett K, Wirth KE, Tchetgen ET, Bachanas P, Mills LA, Lebelonyane R, El-Halabi S, Makhema J, Lockman S, Essex M. Lack of Virological Suppression Among Young HIV-Positive Adults in Botswana. J Acquir Immune Defic Syndr. 2018 Aug 15; 78(5):557-565. PMID: 29771781.
    Citations:    Fields:    
  12. Zash R, Makhema J, Shapiro RL. Neural-Tube Defects with Dolutegravir Treatment from the Time of Conception. N Engl J Med. 2018 09 06; 379(10):979-981. PMID: 30037297.
    Citations: 1     Fields:    Translation:Humans
  13. Moyo S, Gaseitsiwe S, Powis KM, Pretorius Holme M, Mohammed T, Zahralban-Steele M, Yankinde EK, Maphorisa C, Abrams W, Lebelonyane R, Manyake K, Sekoto T, Mmalane M, Gaolathe T, Wirth KE, Makhema J, Lockman S, Clarke W, Essex M, Novitsky V. Undisclosed antiretroviral drug use in Botswana: implication for national estimates. AIDS. 2018 Jul 17; 32(11):1543-1546. PMID: 29762166.
    Citations:    Fields:    
  14. Diphoko T, Gaseitsiwe S, Kasvosve I, Moyo S, Okatch H, Musonda R, Wainberg M, Makhema J, Marlink R, Novitsky V, Essex M. Prevalence of Rilpivirine and Etravirine Resistance Mutations in HIV-1 Subtype C-Infected Patients Failing Nevirapine or Efavirenz-Based Combination Antiretroviral Therapy in Botswana. AIDS Res Hum Retroviruses. 2018 08; 34(8):667-671. PMID: 29732907.
    Citations:    Fields:    
  15. Zash R, Jacobson DL, Diseko M, Mayondi G, Mmalane M, Essex M, Gaolethe T, Petlo C, Lockman S, Holmes LB, Makhema J, Shapiro RL. Comparative safety of dolutegravir-based or efavirenz-based antiretroviral treatment started during pregnancy in Botswana: an observational study. Lancet Glob Health. 2018 07; 6(7):e804-e810. PMID: 29880310.
    Citations: 1     Fields:    
  16. Mupfumi L, Moyo S, Molebatsi K, Thami PK, Anderson M, Mogashoa T, Iketleng T, Makhema J, Marlink R, Kasvosve I, Essex M, Musonda RM, Gaseitsiwe S. Correction: Immunological non-response and low hemoglobin levels are predictors of incident tuberculosis among HIV-infected individuals on Truvada-based therapy in Botswana. PLoS One. 2018; 13(6):e0198711. PMID: 29856867.
    Citations:    Fields:    
  17. Chaudhury S, Mayondi GK, Williams PL, Leidner J, Shapiro R, Diseko M, Ajibola G, Holding P, Tepper V, Makhema J, Petlo C, Seage GR, Lockman S, Kammerer B. In-utero exposure to antiretrovirals and neurodevelopment among HIV-exposed-uninfected children in Botswana. AIDS. 2018 06 01; 32(9):1173-1183. PMID: 29547434.
    Citations:    Fields:    
  18. Ibrahim M, Maswabi K, Ajibola G, Moyo S, Hughes MD, Batlang O, Sakoi M, Auletta-Young C, Vaughan L, Lockman S, Jean-Philippe P, Yu X, Lichterfeld M, Kuritzkes DR, Makhema J, Shapiro RL. Targeted HIV testing at birth supported by low and predictable mother-to-child transmission risk in Botswana. J Int AIDS Soc. 2018 05; 21(5):e25111. PMID: 29852062.
    Citations: 1     Fields:    
  19. Palumbo PJ, Fogel JM, Hudelson SE, Wilson EA, Hart S, Hovind L, Piwowar-Manning E, Wallis C, Papathanasopoulos MA, Morgado MG, Saravanan S, Tripathy S, Eron JJ, Gallant JE, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG, Pilotto JH, Kumwenda J, Akelo V, Godbole SV, Santos BR, Grinsztejn B, Panchia R, Chariyalertsak S, Makhema J, Badal-Faesen S, Chen YQ, Cohen MS, Eshleman SH. HIV Drug Resistance in Adults Receiving Early vs. Delayed Antiretroviral Therapy: HPTN 052. J Acquir Immune Defic Syndr. 2018 04 15; 77(5):484-491. PMID: 29293156.
    Citations:    Fields:    
  20. Powis KM, Lockman S, Ajibola G, Hughes MD, Bennett K, Leidner J, Batlang O, Botebele K, Moyo S, van Widenfelt E, Makhema J, Petlo C, Jibril HB, McIntosh K, Essex M, Shapiro RL. Similar HIV protection from four weeks of zidovudine versus nevirapine prophylaxis among formula-fed infants in Botswana. South Afr J HIV Med. 2018; 19(1):751. PMID: 29707385.
    Citations:    
  21. Mupfumi L, Moyo S, Molebatsi K, Thami PK, Anderson M, Mogashoa T, Iketleng T, Makhema J, Marlink R, Kasvosve I, Essex M, Musonda RM, Gaseitsiwe S. Immunological non-response and low hemoglobin levels are predictors of incident tuberculosis among HIV-infected individuals on Truvada-based therapy in Botswana. PLoS One. 2018; 13(1):e0192030. PMID: 29385208.
    Citations: 1     Fields:    Translation:Humans
  22. Novitsky V, Prague M, Moyo S, Gaolathe T, Mmalane M, Yankinda EK, Chakalisa U, Lebelonyane R, Khan N, Powis KM, Widenfelt E, Gaseitsiwe S, Dryden-Peterson SL, Holme MP, De Gruttola V, Bachanas P, Makhema J, Lockman S, Essex M. High HIV-1 RNA Among Newly Diagnosed People in Botswana. AIDS Res Hum Retroviruses. 2018 03; 34(3):300-306. PMID: 29214845.
    Citations:    Fields:    
  23. Caniglia EC, Zash R, Jacobson DL, Diseko M, Mayondi G, Lockman S, Chen JY, Mmalane M, Makhema J, Hernán MA, Shapiro RL. Emulating a target trial of antiretroviral therapy regimens started before conception and risk of adverse birth outcomes. AIDS. 2018 Jan 02; 32(1):113-120. PMID: 29112066.
    Citations:    Fields:    Translation:Humans
  24. Greer AE, Ou SS, Wilson E, Piwowar-Manning E, Forman MS, McCauley M, Gamble T, Ruangyuttikarn C, Hosseinipour MC, Kumarasamy N, Nyirenda M, Grinsztejn B, Pilotto JH, Kosashunhanan N, Gonçalves de Melo M, Makhema J, Akelo V, Panchia R, Badal-Faesen S, Chen YQ, Cohen MS, Eshleman SH, Thio CL, Valsamakis A. Comparison of Hepatitis B Virus Infection in HIV-Infected and HIV-Uninfected Participants Enrolled in a Multinational Clinical Trial: HPTN 052. J Acquir Immune Defic Syndr. 2017 12 01; 76(4):388-393. PMID: 28749822.
    Citations: 1     Fields:    Translation:HumansCells
  25. Powis KM, Souda S, Lockman S, Ajibola G, Bennett K, Leidner J, Hughes MD, Moyo S, van Widenfelt E, Jibril HB, Makhema J, Essex M, Shapiro RL. Cotrimoxazole prophylaxis was associated with enteric commensal bacterial resistance among HIV-exposed infants in a randomized controlled trial, Botswana. J Int AIDS Soc. 2017 11; 20(3). PMID: 29119726.
    Citations:    Fields:    Translation:HumansCells
  26. N'Guessan KF, Anderson M, Phinius B, Moyo S, Malick A, Mbangiwa T, Choga WT, Makhema J, Marlink R, Essex M, Musonda R, Gaseitsiwe S, Blackard JT. The Impact of Human Pegivirus on CD4 Cell Count in HIV-Positive Persons in Botswana. Open Forum Infect Dis. 2017; 4(4):ofx222. PMID: 29255726.
    Citations: 1     
  27. Zash R, Jacobson DL, Diseko M, Mayondi G, Mmalane M, Essex M, Petlo C, Lockman S, Makhema J, Shapiro RL. Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy. JAMA Pediatr. 2017 10 02; 171(10):e172222. PMID: 28783807.
    Citations: 8     Fields:    Translation:Humans
  28. Rademeyer C, Korber B, Seaman MS, Giorgi EE, Thebus R, Robles A, Sheward DJ, Wagh K, Garrity J, Carey BR, Gao H, Greene KM, Tang H, Bandawe GP, Marais JC, Diphoko TE, Hraber P, Tumba N, Moore PL, Gray GE, Kublin J, McElrath MJ, Vermeulen M, Middelkoop K, Bekker LG, Hoelscher M, Maboko L, Makhema J, Robb ML, Karim SA, Karim QA, Kim JH, Hahn BH, Gao F, Swanstrom R, Morris L, Montefiori DC, Williamson C. Correction: Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization. PLoS Pathog. 2017 Sep; 13(9):e1006641. PMID: 28945784.
    Citations:    Fields:    
  29. Chaudhury S, Williams PL, Mayondi GK, Leidner J, Holding P, Tepper V, Nichols S, Magetse J, Sakoi M, Moabi K, Makhema J, Mdluli C, Jibril H, Seage GR, Kammerer B, Lockman S. Neurodevelopment of HIV-Exposed and HIV-Unexposed Uninfected Children at 24 Months. Pediatrics. 2017 Oct; 140(4). PMID: 28912368.
    Citations: 1     Fields:    Translation:Humans
  30. Ryan K, Anderson M, Gyurova I, Ambroggio L, Moyo S, Sebunya T, Makhema J, Marlink R, Essex M, Musonda R, Gaseitsiwe S, Blackard JT. High Rates of Occult Hepatitis B Virus Infection in HIV-Positive Individuals Initiating Antiretroviral Therapy in Botswana. Open Forum Infect Dis. 2017; 4(4):ofx195. PMID: 29062862.
    Citations: 3     
  31. Ibrahim M, Moyo S, Mohammed T, Mupfumi L, Gaseitsiwe S, Maswabi K, Ajibola G, Gelman R, Batlang O, Sakoi M, Auletta-Young C, Makhema J, Lockman S, Shapiro RL. Brief Report: High Sensitivity and Specificity of the Cepheid Xpert HIV-1 Qualitative Point-of-Care Test Among Newborns in Botswana. J Acquir Immune Defic Syndr. 2017 08 15; 75(5):e128-e131. PMID: 28350554.
    Citations: 1     Fields:    Translation:Humans
  32. Campa A, Baum MK, Bussmann H, Martinez SS, Farahani M, van Widenfelt E, Moyo S, Makhema J, Essex M, Marlink R. The effect of micronutrient supplementation on active TB incidence early in HIV infection in Botswana. Nutr Diet Suppl. 2017; 2017(9):37-45. PMID: 29187783.
    Citations:    
  33. Mosepele M, Hemphill LC, Moloi W, Moyo S, Nkele I, Makhema J, Bennett K, Triant VA, Lockman S. Pre-clinical carotid atherosclerosis and sCD163 among virally suppressed HIV patients in Botswana compared with uninfected controls. PLoS One. 2017; 12(6):e0179994. PMID: 28662159.
    Citations:    Fields:    Translation:HumansCells
  34. Palumbo PJ, Wilson EA, Piwowar-Manning E, McCauley M, Gamble T, Kumwenda N, Makhema J, Kumarasamy N, Chariyalertsak S, Hakim JG, Hosseinipour MC, Melo MG, Godbole SV, Pilotto JH, Grinsztejn B, Panchia R, Chen YQ, Cohen MS, Eshleman SH, Fogel JM. Association of HIV diversity and virologic outcomes in early antiretroviral treatment: HPTN 052. PLoS One. 2017; 12(5):e0177281. PMID: 28481902.
    Citations: 1     Fields:    Translation:HumansCells
  35. Lockman S, Hughes M, Powis K, Ajibola G, Bennett K, Moyo S, van Widenfelt E, Leidner J, McIntosh K, Mazhani L, Makhema J, Essex M, Shapiro R. Effect of co-trimoxazole on mortality in HIV-exposed but uninfected children in Botswana (the Mpepu Study): a double-blind, randomised, placebo-controlled trial. Lancet Glob Health. 2017 05; 5(5):e491-e500. PMID: 28395844.
    Citations: 2     Fields:    Translation:HumansCells
  36. Xie W, Agniel D, Shevchenko A, Malov SV, Svitin A, Cherkasov N, Baum MK, Campa A, Gaseitsiwe S, Bussmann H, Makhema J, Marlink R, Novitsky V, Lee TH, Cai T, O'Brien SJ, Essex M. Genome-Wide Analyses Reveal Gene Influence on HIV Disease Progression and HIV-1C Acquisition in Southern Africa. AIDS Res Hum Retroviruses. 2017 06; 33(6):597-609. PMID: 28132517.
    Citations: 1     Fields:    Translation:HumansCells
  37. Ajibola G, Zash R, Shapiro RL, Batlang O, Botebele K, Bennett K, Chilisa F, Widenfelt EV, Makhema J, Lockman S, Holmes LB, Powis KM. Detecting congenital malformations - Lessons learned from the Mpepu study, Botswana. PLoS One. 2017; 12(3):e0173800. PMID: 28339500.
    Citations:    Fields:    Translation:HumansPHPublic Health
  38. Moyo S, Wilkinson E, Vandormael A, Wang R, Weng J, Kotokwe KP, Gaseitsiwe S, Musonda R, Makhema J, Essex M, Engelbrecht S, de Oliveira T, Novitsky V. Pairwise diversity and tMRCA as potential markers for HIV infection recency. Medicine (Baltimore). 2017 Feb; 96(6):e6041. PMID: 28178146.
    Citations: 1     Fields:    Translation:HumansCells
  39. Zash RM, Souda S, Leidner J, Binda K, Hick C, Powis K, Makhema J, Mmalane M, Essex M, Lockman S, Shapiro RL. High Proportion of Deaths Attributable to HIV Among Postpartum Women in Botswana Despite Widespread Uptake of Antiretroviral Therapy. AIDS Patient Care STDS. 2017 Jan; 31(1):14-19. PMID: 28051898.
    Citations: 1     Fields:    Translation:Humans
  40. Moyo S, Mohammed T, Wirth KE, Prague M, Bennett K, Holme MP, Mupfumi L, Sebogodi P, Moraka NO, Boleo C, Maphorisa CN, Seraise B, Gaseitsiwe S, Musonda RM, van Widenfelt E, Powis KM, Gaolathe T, Tchetgen Tchetgen EJ, Makhema JM, Essex M, Lockman S, Novitsky V. Point-of-Care Cepheid Xpert HIV-1 Viral Load Test in Rural African Communities Is Feasible and Reliable. J Clin Microbiol. 2016 12; 54(12):3050-3055. PMID: 27733636.
    Citations: 2     Fields:    Translation:HumansCells
  41. Sudfeld CR, Lei Q, Chinyanga Y, Tumbare E, Khan N, Dapaah-Siakwan F, Sebaka A, Sibiya J, van Widenfelt E, Shapiro RL, Makhema J, Fawzi WW, Powis KM. Linear Growth Faltering Among HIV-Exposed Uninfected Children. J Acquir Immune Defic Syndr. 2016 10 01; 73(2):182-9. PMID: 27116046.
    Citations: 3     Fields:    Translation:Humans
  42. Moyo S, Kotokwe KP, Mohammed T, Boleo C, Mupfumi L, Chishala S, Tsalaile L, Bussmann H, Gaseitsiwe S, Musonda R, Makhema J, Baum M, Marlink R, Engelbrecht S, Essex M, Novitsky V. Short Communication: Low False Recent Rate of Limiting Antigen-Avidity Assay Combined with HIV-1 RNA Data in Botswana. AIDS Res Hum Retroviruses. 2017 01; 33(1):17-18. PMID: 27481530.
    Citations:    Fields:    Translation:Humans
  43. Anderson M, Gaseitsiwe S, Moyo S, Thami KP, Mohammed T, Setlhare D, Sebunya TK, Powell EA, Makhema J, Blackard JT, Marlink R, Essex M, Musonda RM. Slow CD4+ T-Cell Recovery in Human Immunodeficiency Virus/Hepatitis B Virus-Coinfected Patients Initiating Truvada-Based Combination Antiretroviral Therapy in Botswana. Open Forum Infect Dis. 2016 Sep; 3(3):ofw140. PMID: 27800524.
    Citations: 5     
  44. Zash RM, Shapiro RL, Leidner J, Wester C, McAdam AJ, Hodinka RL, Thior I, Moffat C, Makhema J, McIntosh K, Essex M, Lockman S. The aetiology of diarrhoea, pneumonia and respiratory colonization of HIV-exposed infants randomized to breast- or formula-feeding. Paediatr Int Child Health. 2016 Aug; 36(3):189-97. PMID: 27595698.
    Citations: 2     Fields:    Translation:HumansCells
  45. Rademeyer C, Korber B, Seaman MS, Giorgi EE, Thebus R, Robles A, Sheward DJ, Wagh K, Garrity J, Carey BR, Gao H, Greene KM, Tang H, Bandawe GP, Marais JC, Diphoko TE, Hraber P, Tumba N, Moore PL, Gray GE, Kublin J, McElrath MJ, Vermeulen M, Middelkoop K, Bekker LG, Hoelscher M, Maboko L, Makhema J, Robb ML, Abdool Karim S, Abdool Karim Q, Kim JH, Hahn BH, Gao F, Swanstrom R, Morris L, Montefiori DC, Williamson C. Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization. PLoS Pathog. 2016 07; 12(7):e1005742. PMID: 27434311.
    Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
  46. Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG, Kumwenda J, Grinsztejn B, Pilotto JH, Godbole SV, Chariyalertsak S, Santos BR, Mayer KH, Hoffman IF, Eshleman SH, Piwowar-Manning E, Cottle L, Zhang XC, Makhema J, Mills LA, Panchia R, Faesen S, Eron J, Gallant J, Havlir D, Swindells S, Elharrar V, Burns D, Taha TE, Nielsen-Saines K, Celentano DD, Essex M, Hudelson SE, Redd AD, Fleming TR. Antiretroviral Therapy for the Prevention of HIV-1 Transmission. N Engl J Med. 2016 09 01; 375(9):830-9. PMID: 27424812.
    Citations: 117     Fields:    Translation:HumansCells
  47. Perry ME, Kalenga K, Watkins LF, Mukaya JE, Powis KM, Bennett K, Mmalane M, Makhema J, Shapiro RL. HIV-related mortality at a district hospital in Botswana. Int J STD AIDS. 2017 03; 28(3):277-283. PMID: 27164967.
    Citations:    Fields:    Translation:Humans
  48. Fogel JM, Hudelson SE, Ou SS, Hart S, Wallis C, Morgado MG, Saravanan S, Tripathy S, Hovind L, Piwowar-Manning E, Sabin D, McCauley M, Gamble T, Zhang XC, Eron JJ, Gallant JE, Kumwenda J, Makhema J, Kumarasamy N, Chariyalertsak S, Hakim J, Badal-Faesen S, Akelo V, Hosseinipour MC, Santos BR, Godbole SV, Pilotto JH, Grinsztejn B, Panchia R, Mayer KH, Chen YQ, Cohen MS, Eshleman SH. Brief Report: HIV Drug Resistance in Adults Failing Early Antiretroviral Treatment: Results From the HIV Prevention Trials Network 052 Trial. J Acquir Immune Defic Syndr. 2016 07 01; 72(3):304-9. PMID: 26859828.
    Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
  49. Ogwu A, Moyo S, Powis K, Asmelash A, Lockman S, Moffat C, Leidner J, Makhema J, Essex M, Shapiro R. Predictors of early breastfeeding cessation among HIV-infected women in Botswana. Trop Med Int Health. 2016 Aug; 21(8):1013-1018. PMID: 27224454.
    Citations:    Fields:    
  50. Zash R, Souda S, Chen JY, Binda K, Dryden-Peterson S, Lockman S, Mmalane M, Makhema J, Essex M, Shapiro R. Reassuring Birth Outcomes With Tenofovir/Emtricitabine/Efavirenz Used for Prevention of Mother-to-Child Transmission of HIV in Botswana. J Acquir Immune Defic Syndr. 2016 Apr 01; 71(4):428-36. PMID: 26379069.
    Citations: 11     Fields:    Translation:Humans
  51. Novitsky V, Zahralban-Steele M, McLane MF, Moyo S, van Widenfelt E, Gaseitsiwe S, Makhema J, Essex M. Correction for Novitsky et al., Long-Range HIV Genotyping Using Viral RNA and Proviral DNA for Analysis of HIV Drug Resistance and HIV Clustering. J Clin Microbiol. 2016 Apr; 54(4):1175. PMID: 27016593.
    Citations:    Fields:    
  52. Gaolathe T, Wirth KE, Holme MP, Makhema J, Moyo S, Chakalisa U, Yankinda EK, Lei Q, Mmalane M, Novitsky V, Okui L, van Widenfelt E, Powis KM, Khan N, Bennett K, Bussmann H, Dryden-Peterson S, Lebelonyane R, El-Halabi S, Mills LA, Marukutira T, Wang R, Tchetgen EJ, DeGruttola V, Essex M, Lockman S. Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals: a population-based survey. Lancet HIV. 2016 May; 3(5):e221-30. PMID: 27126489.
    Citations: 28     Fields:    
  53. Farahani M, Novitsky V, Wang R, Bussmann H, Moyo S, Musonda RM, Moeti T, Makhema JM, Essex M, Marlink R. Prognostic Value of HIV-1 RNA on CD4 Trajectories and Disease Progression Among Antiretroviral-Naive HIV-Infected Adults in Botswana: A Joint Modeling Analysis. AIDS Res Hum Retroviruses. 2016 06; 32(6):573-8. PMID: 26830351.
    Citations: 3     Fields:    Translation:Humans
  54. Mayondi GK, Wirth K, Morroni C, Moyo S, Ajibola G, Diseko M, Sakoi M, Magetse JD, Moabi K, Leidner J, Makhema J, Kammerer B, Lockman S. Unintended pregnancy, contraceptive use, and childbearing desires among HIV-infected and HIV-uninfected women in Botswana: across-sectional study. BMC Public Health. 2016 Jan 16; 16:44. PMID: 26774918.
    Citations: 6     Fields:    Translation:Humans
  55. Powis KM, Smeaton L, Hughes MD, Tumbare EA, Souda S, Jao J, Wirth KE, Makhema J, Lockman S, Fawzi W, Essex M, Shapiro RL. In-utero triple antiretroviral exposure associated with decreased growth among HIV-exposed uninfected infants in Botswana. AIDS. 2016 Jan; 30(2):211-20. PMID: 26684818.
    Citations: 6     Fields:    Translation:Humans
  56. Baum MK, Campa A, Page JB, Lai S, Tsalaile L, Martinez SS, Burns P, Williams O, Li Y, van Widenfelt E, Bussmann H, Sikhulele M, Makhema J, Essex M, Marlink R. Recruitment, Follow-Up and Characteristics of HIV Infected Adults who Use Illicit Drugs in Southern Africa. J Drug Abuse. 2015; 1(1). PMID: 26855969.
    Citations:    
  57. Efstathiou JA, Heunis M, Karumekayi T, Makufa R, Bvochora-Nsingo M, Gierga DP, Suneja G, Grover S, Kasese J, Mmalane M, Moffat H, von Paleske A, Makhema J, Dryden-Peterson S. Establishing and Delivering Quality Radiation Therapy in Resource-Constrained Settings: The Story of Botswana. J Clin Oncol. 2016 Jan 01; 34(1):27-35. PMID: 26578607.
    Citations: 2     Fields:    Translation:Humans
  58. Iketleng T, Moyo S, Gaseitsiwe S, Nyombi B, Mitchell RM, Makhema J, Baum MK, Marlink R, Essex M, Musonda R. Plasma Cytokine Levels in Chronic Asymptomatic HIV-1 Subtype C Infection as an Indicator of Disease Progression in Botswana: A Retrospective Case Control Study. AIDS Res Hum Retroviruses. 2016 Apr; 32(4):364-9. PMID: 26414751.
    Citations: 1     Fields:    Translation:HumansCells
  59. Anderson M, Gaseitsiwe S, Moyo S, Wessels MJ, Mohammed T, Sebunya TK, Powell EA, Makhema J, Blackard JT, Marlink R, Essex M, Musonda RM. Molecular characterisation of hepatitis B virus in HIV-1 subtype C infected patients in Botswana. BMC Infect Dis. 2015 Aug 13; 15:335. PMID: 26268355.
    Citations: 1     Fields:    Translation:HumansCells
  60. Novitsky V, Zahralban-Steele M, McLane MF, Moyo S, van Widenfelt E, Gaseitsiwe S, Makhema J, Essex M. Long-Range HIV Genotyping Using Viral RNA and Proviral DNA for Analysis of HIV Drug Resistance and HIV Clustering. J Clin Microbiol. 2015 Aug; 53(8):2581-92. PMID: 26041893.
    Citations:    Fields:    Translation:HumansCells
  61. Novitsky V, Bussmann H, Okui L, Logan A, Moyo S, van Widenfelt E, Mmalane M, Lei Q, Holme MP, Makhema J, Lockman S, Degruttola V, Essex M. Estimated age and gender profile of individuals missed by a home-based HIV testing and counselling campaign in a Botswana community. J Int AIDS Soc. 2015; 18:19918. PMID: 26028155.
    Citations: 2     Fields:    Translation:HumansCells
  62. Powis K, Lockman S, Smeaton L, Hughes MD, Fawzi W, Ogwu A, Moyo S, van Widenfelt E, von Oettingen J, Makhema J, Essex M, Shapiro RL. Vitamin D insufficiency in HIV-infected pregnant women receiving antiretroviral therapy is not associated with morbidity, mortality or growth impairment in their uninfected infants in Botswana. Pediatr Infect Dis J. 2014 Nov; 33(11):1141-7. PMID: 25037041.
    Citations: 1     Fields:    Translation:HumansCells
  63. Plank RM, Wirth KE, Ndubuka NO, Abdullahi R, Nkgau M, Lesetedi C, Powis KM, Mmalane M, Makhema J, Shapiro R, Lockman S. Single-arm evaluation of the AccuCirc device for early infant male circumcision in Botswana. J Acquir Immune Defic Syndr. 2014 May 01; 66(1):1-6. PMID: 24594500.
    Citations: 9     Fields:    Translation:HumansCTClinical Trials
  64. Grinsztejn B, Hosseinipour MC, Ribaudo HJ, Swindells S, Eron J, Chen YQ, Wang L, Ou SS, Anderson M, McCauley M, Gamble T, Kumarasamy N, Hakim JG, Kumwenda J, Pilotto JH, Godbole SV, Chariyalertsak S, de Melo MG, Mayer KH, Eshleman SH, Piwowar-Manning E, Makhema J, Mills LA, Panchia R, Sanne I, Gallant J, Hoffman I, Taha TE, Nielsen-Saines K, Celentano D, Essex M, Havlir D, Cohen MS. Effects of early versus delayed initiation of antiretroviral treatment on clinical outcomes of HIV-1 infection: results from the phase 3 HPTN 052 randomised controlled trial. Lancet Infect Dis. 2014 Apr; 14(4):281-90. PMID: 24602844.
    Citations: 128     Fields:    Translation:HumansCellsCTClinical Trials
  65. Novitsky V, Bussmann H, Logan A, Moyo S, van Widenfelt E, Okui L, Mmalane M, Baca J, Buck L, Phillips E, Tim D, McLane MF, Lei Q, Wang R, Makhema J, Lockman S, DeGruttola V, Essex M. Phylogenetic relatedness of circulating HIV-1C variants in Mochudi, Botswana. PLoS One. 2013; 8(12):e80589. PMID: 24349005.
    Citations: 6     Fields:    Translation:HumansCells
  66. Baum MK, Campa A, Lai S, Sales Martinez S, Tsalaile L, Burns P, Farahani M, Li Y, van Widenfelt E, Page JB, Bussmann H, Fawzi WW, Moyo S, Makhema J, Thior I, Essex M, Marlink R. Effect of micronutrient supplementation on disease progression in asymptomatic, antiretroviral-naive, HIV-infected adults in Botswana: a randomized clinical trial. JAMA. 2013 Nov 27; 310(20):2154-63. PMID: 24281460.
    Citations: 24     Fields:    Translation:Humans
  67. Moyo S, LeCuyer T, Wang R, Gaseitsiwe S, Weng J, Musonda R, Bussmann H, Mine M, Engelbrecht S, Makhema J, Marlink R, Baum MK, Novitsky V, Essex M. Evaluation of the false recent classification rates of multiassay algorithms in estimating HIV type 1 subtype C incidence. AIDS Res Hum Retroviruses. 2014 Jan; 30(1):29-36. PMID: 23937344.
    Citations: 7     Fields:    Translation:HumansCells
  68. Souda S, Gaseitsiwe S, Georgette N, Powis K, Moremedi D, Iketleng T, Leidner J, Moffat C, Ogwu A, Lockman S, Moyo S, Mmalane M, Musonda R, Makhema J, Essex M, Shapiro R. No clinically significant drug-resistance mutations in HIV-1 subtype C-infected women after discontinuation of NRTI-based or PI-based HAART for PMTCT in Botswana. J Acquir Immune Defic Syndr. 2013 Aug 15; 63(5):572-7. PMID: 23542639.
    Citations: 1     Fields:    Translation:HumansCells
  69. Fogel JM, Wang L, Parsons TL, Ou SS, Piwowar-Manning E, Chen Y, Mudhune VO, Hosseinipour MC, Kumwenda J, Hakim JG, Chariyalertsak S, Panchia R, Sanne I, Kumarasamy N, Grinsztejn B, Makhema J, Pilotto J, Santos BR, Mayer KH, McCauley M, Gamble T, Bumpus NN, Hendrix CW, Cohen MS, Eshleman SH. Undisclosed antiretroviral drug use in a multinational clinical trial (HIV Prevention Trials Network 052). J Infect Dis. 2013 Nov 15; 208(10):1624-8. PMID: 23908493.
    Citations: 29     Fields:    Translation:HumansCellsCTClinical Trials
  70. Shapiro RL, Kitch D, Ogwu A, Hughes MD, Lockman S, Powis K, Souda S, Moffat C, Moyo S, McIntosh K, van Widenfelt E, Zwerski S, Mazhani L, Makhema J, Essex M. HIV transmission and 24-month survival in a randomized trial of HAART to prevent MTCT during pregnancy and breastfeeding in Botswana. AIDS. 2013 Jul 31; 27(12):1911-20. PMID: 24180000.
    Citations: 10     Fields:    Translation:Humans
  71. McDonald B, Moyo S, Gabaitiri L, Gaseitsiwe S, Bussmann H, Koethe JR, Musonda R, Makhema J, Novitsky V, Marlink RG, Wester CW, Essex M. Persistently elevated serum interleukin-6 predicts mortality among adults receiving combination antiretroviral therapy in Botswana: results from a clinical trial. AIDS Res Hum Retroviruses. 2013 Jul; 29(7):993-9. PMID: 23590237.
    Citations: 16     Fields:    Translation:HumansCells
  72. Wang R, Weng J, Moyo S, Pain D, Barr CD, Maruapula D, Mongwato D, Makhema J, Novitsky V, Essex M. Short communication: effect of short-course antenatal zidovudine and single-dose nevirapine on the BED capture enzyme immunoassay levels in HIV type 1 subtype C infection. AIDS Res Hum Retroviruses. 2013 Jun; 29(6):901-6. PMID: 23521375.
    Citations: 1     Fields:    Translation:HumansCells
  73. Plank RM, Ndubuka NO, Wirth KE, Mwambona JT, Kebaabetswe P, Bassil B, Lesetedi C, Magetse J, Nkgau M, Makhema J, Mmalane M, Creek T, Powis KM, Shapiro R, Lockman S. A randomized trial of Mogen clamp versus Plastibell for neonatal male circumcision in Botswana. J Acquir Immune Defic Syndr. 2013 Apr 15; 62(5):e131-7. PMID: 23314413.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  74. Powis KM, McElrath TF, Hughes MD, Ogwu A, Souda S, Datwyler SA, von Widenfelt E, Moyo S, Nádas M, Makhema J, Machakaire E, Lockman S, Essex M, Shapiro RL. High viral load and elevated angiogenic markers associated with increased risk of preeclampsia among women initiating highly active antiretroviral therapy in pregnancy in the Mma Bana study, Botswana. J Acquir Immune Defic Syndr. 2013 Apr 15; 62(5):517-24. PMID: 23344545.
    Citations: 5     Fields:    Translation:HumansCells
  75. Shapiro RL, Rossi S, Ogwu A, Moss M, Leidner J, Moffat C, Lockman S, Moyo S, Makhema J, Essex M, Capparelli E. Therapeutic levels of lopinavir in late pregnancy and abacavir passage into breast milk in the Mma Bana Study, Botswana. Antivir Ther. 2013; 18(4):585-90. PMID: 23183881.
    Citations: 3     Fields:    Translation:HumansCells
  76. Chen JY, Ribaudo HJ, Souda S, Parekh N, Ogwu A, Lockman S, Powis K, Dryden-Peterson S, Creek T, Jimbo W, Madidimalo T, Makhema J, Essex M, Shapiro RL. Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana. J Infect Dis. 2012 Dec 01; 206(11):1695-705. PMID: 23066160.
    Citations: 73     Fields:    Translation:Humans
  77. Lin NH, Becerril C, Giguel F, Novitsky V, Moyo S, Makhema J, Essex M, Lockman S, Kuritzkes DR, Sagar M. Env sequence determinants in CXCR4-using human immunodeficiency virus type-1 subtype C. Virology. 2012 Nov 25; 433(2):296-307. PMID: 22954962.
    Citations: 12     Fields:    Translation:HumansCells
  78. MacLeod IJ, Rowley CF, Lockman S, Ogwu A, Moyo S, van Widenfelt E, Mmalane M, Makhema J, Essex M, Shapiro RL. Abacavir alters the transcription of inflammatory cytokines in virologically suppressed, HIV-infected women. J Int AIDS Soc. 2012 Jul 10; 15(2):17393. PMID: 22789611.
    Citations: 3     Fields:    Translation:HumansCells
  79. Rossenkhan R, Novitsky V, Sebunya TK, Leidner J, Hagan JE, Moyo S, Smeaton L, Lockman S, Musonda R, Ndung'u T, Gaseitsiwe S, Thior I, Mmalane M, Makhema J, Essex M, Shapiro R. Infant feeding practices were not associated with breast milk HIV-1 RNA levels in a randomized clinical trial in Botswana. AIDS Behav. 2012 Jul; 16(5):1260-4. PMID: 21901486.
    Citations: 5     Fields:    Translation:Humans
  80. Shapiro RL, Souda S, Parekh N, Binda K, Kayembe M, Lockman S, Svab P, Babitseng O, Powis K, Jimbo W, Creek T, Makhema J, Essex M, Roberts DJ. High prevalence of hypertension and placental insufficiency, but no in utero HIV transmission, among women on HAART with stillbirths in Botswana. PLoS One. 2012; 7(2):e31580. PMID: 22384039.
    Citations: 6     Fields:    Translation:HumansCells
  81. Mine M, Moyo S, Stevens P, Michael K, Novitsky V, Makhaola K, Asmelash A, Molefhabangwe S, Woldegabriel E, Mothowaeng G, Maruta T, Kamhukamwe C, Mangwendeza PM, Holmes-Pretorius M, Mtoni I, Motswaledi M, Musonda R, Ndwapi N, Makhema J, Marlink R, Seipone K, Gaolathe T, Essex M. Immunohaematological reference values for HIV-negative healthy adults in Botswana. Afr J Lab Med. 2012; 1(1). PMID: 23772402.
    Citations: 7     
  82. Matthews LT, Ribaudo HJ, Parekh NK, Chen JY, Binda K, Ogwu A, Makhema J, Souda S, Lockman S, Essex M, Shapiro RL. Birth weight for gestational age norms for a large cohort of infants born to HIV-negative women in Botswana compared with norms for U.S.-born black infants. BMC Pediatr. 2011 Dec 16; 11:115. PMID: 22176889.
    Citations: 7     Fields:    Translation:HumansCells
  83. Mine M, Moyo S, Stevens P, Michael K, Novitsky V, Makhaola K, Asmelash A, Molefhabangwe S, Woldegabriel E, Mothowaeng G, Maruta T, Kamhukamwe C, Mangwendeza PM, Holmes-Pretorius M, Mtoni I, Motswaledi M, Musonda R, Ndwapi N, Makhema J, Marlink R, Seipone K, Gaolathe T, Essex M. Immunohaematological reference values for HIV-negative healthy adults in Botswana. Afr J Lab Med. 2012; 1(1):5. PMID: 29062725.
    Citations: 3     
  84. Dryden-Peterson S, Jayeoba O, Hughes MD, Jibril H, Keapoletswe K, Tlale J, Modise TA, Asmelash A, Moyo S, van Widenfelt E, Makhema J, Essex M, Shapiro RL, Lockman S. Highly active antiretroviral therapy versus zidovudine for prevention of mother-to-child transmission in a programmatic setting, Botswana. J Acquir Immune Defic Syndr. 2011 Nov 01; 58(3):353-7. PMID: 21792062.
    Citations: 11     Fields:    Translation:Humans
  85. Novitsky V, Wang R, Baca J, Margolin L, McLane MF, Moyo S, van Widenfelt E, Makhema J, Essex M. Evolutionary gamut of in vivo Gag substitutions during early HIV-1 subtype C infection. Virology. 2011 Dec 20; 421(2):119-28. PMID: 22014506.
    Citations: 2     Fields:    Translation:HumansCells
  86. Eshleman SH, Hudelson SE, Redd AD, Wang L, Debes R, Chen YQ, Martens CA, Ricklefs SM, Selig EJ, Porcella SF, Munshaw S, Ray SC, Piwowar-Manning E, McCauley M, Hosseinipour MC, Kumwenda J, Hakim JG, Chariyalertsak S, de Bruyn G, Grinsztejn B, Kumarasamy N, Makhema J, Mayer KH, Pilotto J, Santos BR, Quinn TC, Cohen MS, Hughes JP. Analysis of genetic linkage of HIV from couples enrolled in the HIV Prevention Trials Network 052 trial. J Infect Dis. 2011 Dec 15; 204(12):1918-26. PMID: 21990420.
    Citations: 41     Fields:    Translation:HumansCellsCTClinical Trials
  87. Macleod IJ, O'Donnell B, Moyo S, Lockman S, Shapiro RL, Kayembe M, van Widenfelt E, Makhema J, Essex M, Wester C. Prevalence of human papillomavirus genotypes and associated cervical squamous intraepithelial lesions in HIV-infected women in Botswana. J Med Virol. 2011 Oct; 83(10):1689-95. PMID: 21837784.
    Citations: 12     Fields:    Translation:HumansCells
  88. Moyo S, Bussmann H, Mangwendeza P, Dusara P, Gaolathe T, Mine M, Musonda R, van Widenfelt E, Novitsky V, Makhema J, Marlink RG, Essex M, Wester CW. Validation of A Point-of-Care Lactate Device For Screening At-Risk Adults Receiving Combination Antiretroviral Therapy In Botswana. J Antivir Antiretrovir. 2011 Oct; 3(4):45-48. PMID: 23087782.
    Citations: 2     
  89. Powis KM, Kitch D, Ogwu A, Hughes MD, Lockman S, Leidner J, van Widenfelt E, Moffat C, Moyo S, Makhema J, Essex M, Shapiro RL. Increased risk of preterm delivery among HIV-infected women randomized to protease versus nucleoside reverse transcriptase inhibitor-based HAART during pregnancy. J Infect Dis. 2011 Aug 15; 204(4):506-14. PMID: 21791651.
    Citations: 40     Fields:    Translation:Humans
  90. Novitsky V, Ndung'u T, Wang R, Bussmann H, Chonco F, Makhema J, De Gruttola V, Walker BD, Essex M. Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection. AIDS. 2011 Jul 31; 25(12):1515-22. PMID: 21505307.
    Citations: 34     Fields:    Translation:HumansCells
  91. Parekh N, Ribaudo H, Souda S, Chen J, Mmalane M, Powis K, Essex M, Makhema J, Shapiro RL. Risk factors for very preterm delivery and delivery of very-small-for-gestational-age infants among HIV-exposed and HIV-unexposed infants in Botswana. Int J Gynaecol Obstet. 2011 Oct; 115(1):20-5. PMID: 21767835.
    Citations: 8     Fields:    Translation:Humans
  92. Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG, Kumwenda J, Grinsztejn B, Pilotto JH, Godbole SV, Mehendale S, Chariyalertsak S, Santos BR, Mayer KH, Hoffman IF, Eshleman SH, Piwowar-Manning E, Wang L, Makhema J, Mills LA, de Bruyn G, Sanne I, Eron J, Gallant J, Havlir D, Swindells S, Ribaudo H, Elharrar V, Burns D, Taha TE, Nielsen-Saines K, Celentano D, Essex M, Fleming TR. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011 Aug 11; 365(6):493-505. PMID: 21767103.
    Citations: 2149     Fields:    Translation:HumansCells
  93. Lin NH, Smeaton LM, Giguel F, Novitsky V, Moyo S, Mitchell RM, Makhema J, Essex M, Lockman S, Kuritzkes DR. Prevalence and clinical associations of CXCR4-using HIV-1 among treatment-naive subtype C-infected women in Botswana. J Acquir Immune Defic Syndr. 2011 May 01; 57(1):46-50. PMID: 21346588.
    Citations: 6     Fields:    Translation:HumansCells
  94. Dryden-Peterson S, Shapiro RL, Hughes MD, Powis K, Ogwu A, Moffat C, Moyo S, Makhema J, Essex M, Lockman S. Increased risk of severe infant anemia after exposure to maternal HAART, Botswana. J Acquir Immune Defic Syndr. 2011 Apr 15; 56(5):428-36. PMID: 21266910.
    Citations: 11     Fields:    Translation:HumansCells
  95. Powis KM, Smeaton L, Ogwu A, Lockman S, Dryden-Peterson S, van Widenfelt E, Leidner J, Makhema J, Essex M, Shapiro RL. Effects of in utero antiretroviral exposure on longitudinal growth of HIV-exposed uninfected infants in Botswana. J Acquir Immune Defic Syndr. 2011 Feb 01; 56(2):131-8. PMID: 21124227.
    Citations: 21     Fields:    Translation:Humans
  96. Baeten JM, Lingappa J, Beck I, Frenkel LM, Pepper G, Celum C, Wald A, Fife KH, Were E, Mugo N, Sanchez J, Essex M, Makhema J, Kiarie J, Farquhar C, Corey L. Herpes simplex virus type 2 suppressive therapy with acyclovir or valacyclovir does not select for specific HIV-1 resistance in HIV-1/HSV-2 dually infected persons. J Infect Dis. 2011 Jan 01; 203(1):117-21. PMID: 21148504.
    Citations: 12     Fields:    Translation:HumansCells
  97. Plank RM, Makhema J, Kebaabetswe P, Hussein F, Lesetedi C, Halperin D, Bassil B, Shapiro R, Lockman S. Acceptability of infant male circumcision as part of HIV prevention and male reproductive health efforts in Gaborone, Botswana, and surrounding areas. AIDS Behav. 2010 Oct; 14(5):1198-202. PMID: 19924526.
    Citations: 17     Fields:    Translation:Humans
  98. Shapiro RL, Hughes MD, Ogwu A, Kitch D, Lockman S, Moffat C, Makhema J, Moyo S, Thior I, McIntosh K, van Widenfelt E, Leidner J, Powis K, Asmelash A, Tumbare E, Zwerski S, Sharma U, Handelsman E, Mburu K, Jayeoba O, Moko E, Souda S, Lubega E, Akhtar M, Wester C, Tuomola R, Snowden W, Martinez-Tristani M, Mazhani L, Essex M. Antiretroviral regimens in pregnancy and breast-feeding in Botswana. N Engl J Med. 2010 Jun 17; 362(24):2282-94. PMID: 20554983.
    Citations: 154     Fields:    Translation:HumansCells
  99. Chen JY, Ogwu AC, Svab P, Lockman S, Moffat HJ, Gaolathe T, Moilwa S, Størdal K, Dryden-Peterson S, Moffat C, Makhema J, Essex M, Shapiro RL. Antiretroviral treatment initiation among HIV-infected pregnant women with low CD4(+) cell counts in Gaborone, Botswana. J Acquir Immune Defic Syndr. 2010 May 01; 54(1):102-6. PMID: 19864957.
    Citations: 9     Fields:    Translation:Humans
  100. MacLeod IJ, Rowley CF, Thior I, Wester C, Makhema J, Essex M, Lockman S. Minor resistant variants in nevirapine-exposed infants may predict virologic failure on nevirapine-containing ART. J Clin Virol. 2010 Jul; 48(3):162-7. PMID: 20427228.
    Citations: 20     Fields:    Translation:HumansCells
  101. Novitsky V, Wang R, Bussmann H, Lockman S, Baum M, Shapiro R, Thior I, Wester C, Wester CW, Ogwu A, Asmelash A, Musonda R, Campa A, Moyo S, van Widenfelt E, Mine M, Moffat C, Mmalane M, Makhema J, Marlink R, Gilbert P, Seage GR, DeGruttola V, Essex M. HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the "test-and-treat" approach to reduce HIV transmission. PLoS One. 2010 Apr 12; 5(4):e10148. PMID: 20405044.
    Citations: 28     Fields:    Translation:AnimalsCellsPHPublic Health
  102. Lingappa JR, Baeten JM, Wald A, Hughes JP, Thomas KK, Mujugira A, Mugo N, Bukusi EA, Cohen CR, Katabira E, Ronald A, Kiarie J, Farquhar C, Stewart GJ, Makhema J, Essex M, Were E, Fife KH, de Bruyn G, Gray GE, McIntyre JA, Manongi R, Kapiga S, Coetzee D, Allen S, Inambao M, Kayitenkore K, Karita E, Kanweka W, Delany S, Rees H, Vwalika B, Magaret AS, Wang RS, Kidoguchi L, Barnes L, Ridzon R, Corey L, Celum C. Daily acyclovir for HIV-1 disease progression in people dually infected with HIV-1 and herpes simplex virus type 2: a randomised placebo-controlled trial. Lancet. 2010 Mar 06; 375(9717):824-33. PMID: 20153888.
    Citations: 74     Fields:    Translation:HumansCells
  103. Celum C, Wald A, Lingappa JR, Magaret AS, Wang RS, Mugo N, Mujugira A, Baeten JM, Mullins JI, Hughes JP, Bukusi EA, Cohen CR, Katabira E, Ronald A, Kiarie J, Farquhar C, Stewart GJ, Makhema J, Essex M, Were E, Fife KH, de Bruyn G, Gray GE, McIntyre JA, Manongi R, Kapiga S, Coetzee D, Allen S, Inambao M, Kayitenkore K, Karita E, Kanweka W, Delany S, Rees H, Vwalika B, Stevens W, Campbell MS, Thomas KK, Coombs RW, Morrow R, Whittington WL, McElrath MJ, Barnes L, Ridzon R, Corey L. Acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2. N Engl J Med. 2010 Feb 04; 362(5):427-39. PMID: 20089951.
    Citations: 226     Fields:    Translation:HumansCells
  104. Wester CW, Thomas AM, Bussmann H, Moyo S, Makhema JM, Gaolathe T, Novitsky V, Essex M, deGruttola V, Marlink RG. Non-nucleoside reverse transcriptase inhibitor outcomes among combination antiretroviral therapy-treated adults in Botswana. AIDS. 2010 Jan; 24 Suppl 1:S27-36. PMID: 20023437.
    Citations: 19     Fields:    Translation:HumansCells
  105. Rossenkhan R, Ndung'u T, Sebunya TK, Hagan JE, Shapiro R, Novitsky V, Moyo SM, Thior I, Lockman S, Mitchell R, Kim S, Musonda R, van Widenfelt E, Makhema J, Essex M. Temporal reduction of HIV type 1 viral load in breast milk by single-dose nevirapine during prevention of MTCT. AIDS Res Hum Retroviruses. 2009 Dec; 25(12):1261-4. PMID: 20001515.
    Citations: 3     Fields:    Translation:HumansCells
  106. Novitsky V, Wang R, Margolin L, Baca J, Kebaabetswe L, Rossenkhan R, Bonney C, Herzig M, Nkwe D, Moyo S, Musonda R, Woldegabriel E, van Widenfelt E, Makhema J, Lagakos S, Essex M. Timing constraints of in vivo gag mutations during primary HIV-1 subtype C infection. PLoS One. 2009 Nov 05; 4(11):e7727. PMID: 19890401.
    Citations: 21     Fields:    Translation:HumansCells
  107. Kebaabetswe P, Ndase P, Mujugira A, Sekoto T, Ntshimane M, Owor A, Makhema J, Thior I, Essex M. Perceptions of couple HIV counseling and testing in Botswana: a stakeholder analysis. Patient Educ Couns. 2010 Apr; 79(1):120-3. PMID: 19682831.
    Citations: 6     Fields:    Translation:HumansCells
  108. Bussmann H, Wester CW, Thomas A, Novitsky V, Okezie R, Muzenda T, Gaolathe T, Ndwapi N, Mawoko N, Widenfelt E, Moyo S, Musonda R, Mine M, Makhema J, Moffat H, Essex M, Degruttola V, Marlink RG. Response to zidovudine/didanosine-containing combination antiretroviral therapy among HIV-1 subtype C-infected adults in Botswana: two-year outcomes from a randomized clinical trial. J Acquir Immune Defic Syndr. 2009 May 01; 51(1):37-46. PMID: 19282782.
    Citations: 24     Fields:    Translation:HumansCells
  109. Lingappa JR, Kahle E, Mugo N, Mujugira A, Magaret A, Baeten J, Bukusi EA, Cohen CR, Katabira E, Ronald A, Kiarie J, Farquhar C, Stewart GJ, Makhema J, Essex M, Were E, Fife K, Debruyn G, Gray G, McIntyre J, Manongi R, Kapiga S, Coetzee D, Allen S, Inambao M, Kayitenkore K, Karita E, Kanweka W, Delany S, Rees H, Vwalika B, Coombs RW, Morrow R, Whittington W, Corey L, Wald A, Celum C. Characteristics of HIV-1 discordant couples enrolled in a trial of HSV-2 suppression to reduce HIV-1 transmission: the partners study. PLoS One. 2009; 4(4):e5272. PMID: 19404392.
    Citations: 45     Fields:    Translation:HumansCellsCTClinical Trials
  110. Shapiro RL, Smeaton L, Lockman S, Thior I, Rossenkhan R, Wester C, Stevens L, Moffat C, Arimi P, Ndase P, Asmelash A, Leidner J, Novitsky V, Makhema J, Essex M. Risk factors for early and late transmission of HIV via breast-feeding among infants born to HIV-infected women in a randomized clinical trial in Botswana. J Infect Dis. 2009 Feb 01; 199(3):414-8. PMID: 19090775.
    Citations: 11     Fields:    Translation:HumansCells
  111. Novitsky V, Woldegabriel E, Kebaabetswe L, Rossenkhan R, Mlotshwa B, Bonney C, Finucane M, Musonda R, Moyo S, Wester C, van Widenfelt E, Makhema J, Lagakos S, Essex M. Viral load and CD4+ T-cell dynamics in primary HIV-1 subtype C infection. J Acquir Immune Defic Syndr. 2009 Jan 01; 50(1):65-76. PMID: 19295336.
    Citations: 26     Fields:    Translation:HumansCells
  112. Novitsky V, Lagakos S, Herzig M, Bonney C, Kebaabetswe L, Rossenkhan R, Nkwe D, Margolin L, Musonda R, Moyo S, Woldegabriel E, van Widenfelt E, Makhema J, Essex M. Evolution of proviral gp120 over the first year of HIV-1 subtype C infection. Virology. 2009 Jan 05; 383(1):47-59. PMID: 18973914.
    Citations: 24     Fields:    Translation:HumansCells
  113. Novitsky V, Woldegabriel E, Wester C, McDonald E, Rossenkhan R, Ketunuti M, Makhema J, Seage GR, Essex M. Identification of primary HIV-1C infection in Botswana. AIDS Care. 2008 Aug; 20(7):806-11. PMID: 18608056.
    Citations: 22     Fields:    Translation:HumansCells
  114. Bussmann C, Rotz P, Ndwapi N, Baxter D, Bussmann H, Wester CW, Ncube P, Avalos A, Mine M, Mabe E, Burns P, Cardiello P, Makhema J, Marlink R. Strengthening healthcare capacity through a responsive, country-specific, training standard: the KITSO AIDS training program's support of Botswana's national antiretroviral therapy rollout. Open AIDS J. 2008; 2:10-6. PMID: 18923699.
    Citations: 8     
  115. Lingappa JR, Lambdin B, Bukusi EA, Ngure K, Kavuma L, Inambao M, Kanweka W, Allen S, Kiarie JN, Makhema J, Were E, Manongi R, Coetzee D, de Bruyn G, Delany-Moretlwe S, Magaret A, Mugo N, Mujugira A, Ndase P, Celum C. Regional differences in prevalence of HIV-1 discordance in Africa and enrollment of HIV-1 discordant couples into an HIV-1 prevention trial. PLoS One. 2008 Jan 09; 3(1):e1411. PMID: 18183292.
    Citations: 68     Fields:    Translation:HumansCTClinical Trials
  116. Riviello ED, Sterling TR, Shepherd B, Fantan T, Makhema J. HIV in the workplace in Botswana: incidence, prevalence, and disease severity. AIDS Res Hum Retroviruses. 2007 Dec; 23(12):1453-60. PMID: 18160001.
    Citations: 3     Fields:    Translation:Humans
  117. Wester CW, Okezie OA, Thomas AM, Bussmann H, Moyo S, Muzenda T, Makhema J, van Widenfelt E, Musonda R, Novitsky V, Gaolathe T, Ndwapi N, Essex M, Kuritzkes DR, DeGruttola V, Marlink RG. Higher-than-expected rates of lactic acidosis among highly active antiretroviral therapy-treated women in Botswana: preliminary results from a large randomized clinical trial. J Acquir Immune Defic Syndr. 2007 Nov 01; 46(3):318-22. PMID: 18090299.
    Citations: 33     Fields:    Translation:Humans
  118. Novitsky V, Gaolathe T, Woldegabriel E, Makhema J, Essex M. A seronegative case of HIV-1 subtype C infection in Botswana. Clin Infect Dis. 2007 Sep 01; 45(5):e68-71. PMID: 17682982.
    Citations: 6     Fields:    Translation:HumansCells
  119. Shapiro RL, Lockman S, Kim S, Smeaton L, Rahkola JT, Thior I, Wester C, Moffat C, Arimi P, Ndase P, Asmelash A, Stevens L, Montano M, Makhema J, Essex M, Janoff EN. Infant morbidity, mortality, and breast milk immunologic profiles among breast-feeding HIV-infected and HIV-uninfected women in Botswana. J Infect Dis. 2007 Aug 15; 196(4):562-9. PMID: 17624842.
    Citations: 45     Fields:    Translation:HumansCells
  120. Bussmann H, Wester CW, Wester CN, Lekoko B, Okezie O, Thomas AM, DeGruttola SM, Makhema J, Essex M, Marlink RG. Pregnancy rates and birth outcomes among women on efavirenz-containing highly active antiretroviral therapy in Botswana. J Acquir Immune Defic Syndr. 2007 Jul 01; 45(3):269-73. PMID: 17450102.
    Citations: 21     Fields:    Translation:HumansCTClinical Trials
  121. Lockman S, Shapiro RL, Smeaton LM, Wester C, Thior I, Stevens L, Chand F, Makhema J, Moffat C, Asmelash A, Ndase P, Arimi P, van Widenfelt E, Mazhani L, Novitsky V, Lagakos S, Essex M. Response to antiretroviral therapy after a single, peripartum dose of nevirapine. N Engl J Med. 2007 Jan 11; 356(2):135-47. PMID: 17215531.
    Citations: 135     Fields:    Translation:HumansCells
  122. Wolfe WR, Weiser SD, Bangsberg DR, Thior I, Makhema JM, Dickinson DB, Mompati KF, Marlink RG. Effects of HIV-related stigma among an early sample of patients receiving antiretroviral therapy in Botswana. AIDS Care. 2006 Nov; 18(8):931-3. PMID: 17012082.
    Citations: 31     Fields:    Translation:Humans
  123. Thior I, Lockman S, Smeaton LM, Shapiro RL, Wester C, Heymann SJ, Gilbert PB, Stevens L, Peter T, Kim S, van Widenfelt E, Moffat C, Ndase P, Arimi P, Kebaabetswe P, Mazonde P, Makhema J, McIntosh K, Novitsky V, Lee TH, Marlink R, Lagakos S, Essex M. Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study. JAMA. 2006 Aug 16; 296(7):794-805. PMID: 16905785.
    Citations: 121     Fields:    Translation:HumansCells
  124. Shapiro RL, Thior I, Gilbert PB, Lockman S, Wester C, Smeaton LM, Stevens L, Heymann SJ, Ndung'u T, Gaseitsiwe S, Novitsky V, Makhema J, Lagakos S, Essex M. Maternal single-dose nevirapine versus placebo as part of an antiretroviral strategy to prevent mother-to-child HIV transmission in Botswana. AIDS. 2006 Jun 12; 20(9):1281-8. PMID: 16816557.
    Citations: 29     Fields:    Translation:HumansCells
  125. Weiser S, Wolfe W, Bangsberg D, Thior I, Gilbert P, Makhema J, Kebaabetswe P, Dickenson D, Mompati K, Essex M, Marlink R. Barriers to antiretroviral adherence for patients living with HIV infection and AIDS in Botswana. J Acquir Immune Defic Syndr. 2003 Nov 01; 34(3):281-8. PMID: 14600572.
    Citations: 138     Fields:    Translation:HumansCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.