Harvard Catalyst Profiles

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Young-Bum Kim, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK123002 (KIM, YOUNG-BUM) May 1, 2020 - Apr 30, 2024
    NIH
    Control of leptin transport system by LRP
    Role: Principal Investigator
  2. R01DK106076 (KIM, YOUNG-BUM) Jul 1, 2017 - Jun 30, 2021
    NIH
    Control of Energy Balance by ApoJ Signaling
    Role: Principal Investigator
  3. R01DK111529 (KIM, YOUNG-BUM) Sep 20, 2016 - Jul 31, 2021
    NIH
    ApoJ as a novel hepatokine targeting muscle glucose metabolism
    Role: Principal Investigator
  4. R01DK094040 (KIM, YOUNG-BUM) May 19, 2012 - Sep 30, 2016
    NIH
    Leptin Signaling in Hypothalamic Neurons and Glutamate Receptors
    Role: Principal Investigator
  5. R01DK083567 (KIM, YOUNG-BUM) Mar 1, 2010 - Feb 29, 2020
    NIH
    ROCK1 signaling in glucose metabolism
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Penumatsa KC, Singhal AA, Warburton RR, Bear MD, Bhedi CD, Nasirova S, Wilson JL, Qi G, Preston IR, Hill NS, Fanburg BL, Kim YB, Toksoz D. Vascular smooth muscle ROCK1 contributes to hypoxia-induced pulmonary hypertension development in mice. Biochem Biophys Res Commun. 2022 Mar 09; 604:137-143. PMID: 35303680.
    Citations:    
  2. Yu F, Hou ZS, Luo HR, Cui XF, Xiao J, Kim YB, Li JL, Feng WR, Tang YK, Li HX, Su SY, Song CY, Wang MY, Xu P. Zinc alters behavioral phenotypes, neurotransmitter signatures, and immune homeostasis in male zebrafish (Danio rerio). Sci Total Environ. 2022 Mar 01; 828:154099. PMID: 35240190.
    Citations:    
  3. Lee JS, Chae S, Nan J, Koo YD, Lee SA, Park YJ, Hwang D, Han W, Lee DS, Kim YB, Chung SS, Park KS. SENP2 suppresses browning of white adipose tissues by de-conjugating SUMO from C/EBPß. Cell Rep. 2022 02 22; 38(8):110408. PMID: 35196497.
    Citations:    
  4. Duquenne M, Folgueira C, Bourouh C, Millet M, Silva A, Clasadonte J, Imbernon M, Fernandois D, Martinez-Corral I, Kusumakshi S, Caron E, Rasika S, Deliglia E, Jouy N, Oishi A, Mazzone M, Trinquet E, Tavernier J, Kim YB, Ory S, Jockers R, Schwaninger M, Boehm U, Nogueiras R, Annicotte JS, Gasman S, Dam J, Prévot V. Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function. Nat Metab. 2021 08; 3(8):1071-1090. PMID: 34341568.
    Citations:    
  5. Kang GM, Min SH, Lee CH, Kim JY, Lim HS, Choi MJ, Jung SB, Park JW, Kim S, Park CB, Dugu H, Choi JH, Jang WH, Park SE, Cho YM, Kim JG, Kim KG, Choi CS, Kim YB, Lee C, Shong M, Kim MS. Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism. Cell Metab. 2021 02 02; 33(2):334-349.e6. PMID: 33535098.
    Citations:    
  6. Kang MC, Seo JA, Lee H, Uner A, Yang WM, Cruz Rodrigues KCD, Kim HJ, Li W, Campbell JN, Dagon Y, Kim YB. LRP1 regulates food intake and energy balance in GABAergic neurons independently of leptin action. Am J Physiol Endocrinol Metab. 2021 02 01; 320(2):E379-E389. PMID: 33356995.
    Citations:    
  7. Sousa-Lima I, Fernandes AB, Patarrão RS, Kim YB, Macedo MP. S-Nitrosoglutathione Reverts Dietary Sucrose-Induced Insulin Resistance. Antioxidants (Basel). 2020 Sep 15; 9(9). PMID: 32942712.
    Citations:    
  8. Campolim CM, Weissmann L, Ferreira CKO, Zordão OP, Dornellas APS, de Castro G, Zanotto TM, Boico VF, Quaresma PGF, Lima RPA, Donato J, Veras MM, Saldiva PHN, Kim YB, Prada PO. Short-term exposure to air pollution (PM2.5) induces hypothalamic inflammation, and long-term leads to leptin resistance and obesity via Tlr4/Ikbke in mice. Sci Rep. 2020 06 23; 10(1):10160. PMID: 32576879.
    Citations: 3     Fields:    Translation:AnimalsCellsPHPublic Health
  9. Seo JA, Kang MC, Yang WM, Hwang WM, Kim SS, Hong SH, Heo JI, Vijyakumar A, Pereira de Moura L, Uner A, Huang H, Lee SH, Lima IS, Park KS, Kim MS, Dagon Y, Willnow TE, Aroda V, Ciaraldi TP, Henry RR, Kim YB. Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity. Nat Commun. 2020 04 24; 11(1):2024. PMID: 32332780.
    Citations: 9     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  10. Kim OH, Booth CJ, Choi HS, Lee J, Kang J, Hur J, Jung WJ, Jung YS, Choi HJ, Kim H, Auh JH, Kim JW, Cha JY, Lee YJ, Lee CS, Choi C, Jung YJ, Yang JY, Im SS, Lee DH, Cho SW, Kim YB, Park KS, Park YJ, Oh BC. High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss. Elife. 2020 04 09; 9. PMID: 32271147.
    Citations: 8     Fields:    Translation:Animals
  11. Park HJ, Jang HR, Park SY, Kim YB, Lee HY, Choi CS. The essential role of fructose-1,6-bisphosphatase 2 enzyme in thermal homeostasis upon cold stress. Exp Mol Med. 2020 03; 52(3):485-496. PMID: 32203098.
    Citations: 1     Fields:    Translation:AnimalsCells
  12. Jeon YK, Kim SS, Kim JH, Kim HJ, Kim HJ, Park JJ, Cho YS, Joung SH, Kim JR, Kim BH, Song SH, Kim IJ, Kim YK, Kim YB. Combined Aerobic and Resistance Exercise Training Reduces Circulating Apolipoprotein J Levels and Improves Insulin Resistance in Postmenopausal Diabetic Women. Diabetes Metab J. 2020 02; 44(1):103-112. PMID: 32097999.
    Citations: 4     Translation:Humans
  13. Üner AG, Keçik O, Quaresma PGF, De Araujo TM, Lee H, Li W, Kim HJ, Chung M, Bjørbæk C, Kim YB. Role of POMC and AgRP neuronal activities on glycaemia in mice. Sci Rep. 2019 09 10; 9(1):13068. PMID: 31506541.
    Citations: 13     Fields:    Translation:AnimalsCells
  14. Kim HI, Lee JS, Kwak BK, Hwang WM, Kim MJ, Kim YB, Chung SS, Park KS. Metformin Ameliorates Lipotoxic ß-Cell Dysfunction through a Concentration-Dependent Dual Mechanism of Action. Diabetes Metab J. 2019 12; 43(6):854-866. PMID: 31339010.
    Citations: 5     Translation:AnimalsCells
  15. Koo YD, Lee JS, Lee SA, Quaresma PGF, Bhat R, Haynes WG, Park YJ, Kim YB, Chung SS, Park KS. SUMO-specific protease 2 mediates leptin-induced fatty acid oxidation in skeletal muscle. Metabolism. 2019 06; 95:27-35. PMID: 30902749.
    Citations: 4     Fields:    Translation:AnimalsCells
  16. de Araujo TM, Razolli DS, Correa-da-Silva F, de Lima-Junior JC, Gaspar RS, Sidarta-Oliveira D, Victorio SC, Donato J, Kim YB, Velloso LA. The partial inhibition of hypothalamic IRX3 exacerbates obesity. EBioMedicine. 2019 Jan; 39:448-460. PMID: 30522931.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  17. Mendes NF, Kim YB, Velloso LA, Araújo EP. Hypothalamic Microglial Activation in Obesity: A Mini-Review. Front Neurosci. 2018; 12:846. PMID: 30524228.
    Citations: 24     
  18. Huang H, Lee SH, Sousa-Lima I, Kim SS, Hwang WM, Dagon Y, Yang WM, Cho S, Kang MC, Seo JA, Shibata M, Cho H, Belew GD, Bhin J, Desai BN, Ryu MJ, Shong M, Li P, Meng H, Chung BH, Hwang D, Kim MS, Park KS, Macedo MP, White M, Jones J, Kim YB. Rho-kinase/AMPK axis regulates hepatic lipogenesis during overnutrition. J Clin Invest. 2018 12 03; 128(12):5335-5350. PMID: 30226474.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  19. Lee CH, Kim HJ, Lee YS, Kang GM, Lim HS, Lee SH, Song DK, Kwon O, Hwang I, Son M, Byun K, Sung YH, Kim S, Kim JB, Choi EY, Kim YB, Kim K, Kweon MN, Sohn JW, Kim MS. Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation. Cell Rep. 2018 10 23; 25(4):934-946.e5. PMID: 30355499.
    Citations: 25     Fields:    Translation:AnimalsCells
  20. Seo JA, Kim YB. TET2: Is a potential gatekeeper for the action of thiazolidinedione in fat cells? Metabolism. 2018 12; 89:A1-A2. PMID: 30296401.
    Citations:    Fields:    Translation:Cells
  21. Oh AR, Sohn S, Lee J, Park JM, Nam KT, Hahm KB, Kim YB, Lee HJ, Cha JY. ChREBP deficiency leads to diarrhea-predominant irritable bowel syndrome. Metabolism. 2018 08; 85:286-297. PMID: 29669261.
    Citations: 13     Fields:    Translation:AnimalsCells
  22. Diep DTV, Hong K, Khun T, Zheng M, Ul-Haq A, Jun HS, Kim YB, Chun KH. Anti-adipogenic effects of KD025 (SLx-2119), a ROCK2-specific inhibitor, in 3T3-L1 cells. Sci Rep. 2018 02 06; 8(1):2477. PMID: 29410516.
    Citations: 18     Fields:    Translation:AnimalsCells
  23. Seo JA, Kang MC, Ciaraldi TP, Kim SS, Park KS, Choe C, Hwang WM, Lim DM, Farr O, Mantzoros C, Henry RR, Kim YB. Circulating ApoJ is closely associated with insulin resistance in human subjects. Metabolism. 2018 01; 78:155-166. PMID: 28986164.
    Citations: 9     Fields:    Translation:Humans
  24. Kim SS, Song SH, Kim JH, Jeon YK, Kim BH, Kang MC, Chun SW, Hong SH, Chung M, Kim YK, Kim IJ, Kim YB. Urine clusterin/apolipoprotein J is linked to tubular damage and renal outcomes in patients with type 2 diabetes mellitus. Clin Endocrinol (Oxf). 2017 Aug; 87(2):156-164. PMID: 28434209.
    Citations: 4     Fields:    Translation:Humans
  25. Han JH, Oh TJ, Lee G, Maeng HJ, Lee DH, Kim KM, Choi SH, Jang HC, Lee HS, Park KS, Kim YB, Lim S. The beneficial effects of empagliflozin, an SGLT2 inhibitor, on atherosclerosis in ApoE -/- mice fed a western diet. Diabetologia. 2017 02; 60(2):364-376. PMID: 27866224.
    Citations: 67     Fields:    Translation:HumansAnimalsCells
  26. Lim S, Lee GY, Park HS, Lee DH, Tae Jung O, Kyoung Min K, Kim YB, Jun HS, Hak Chul J, Park KS. Attenuation of carotid neointimal formation after direct delivery of a recombinant adenovirus expressing glucagon-like peptide-1 in diabetic rats. Cardiovasc Res. 2017 02; 113(2):183-194. PMID: 27702762.
    Citations: 14     Fields:    Translation:AnimalsCells
  27. Dagon Y, Mantzoros CS, Kim YB. AMPK?Sirt1: From a signaling network to a combination drug. Metabolism. 2016 11; 65(11):1692-1694. PMID: 27558832.
    Citations: 4     Fields:    Translation:Cells
  28. Sousa-Lima I, Park SY, Chung M, Jung HJ, Kang MC, Gaspar JM, Seo JA, Macedo MP, Park KS, Mantzoros C, Lee SH, Kim YB. Methylsulfonylmethane (MSM), an organosulfur compound, is effective against obesity-induced metabolic disorders in mice. Metabolism. 2016 10; 65(10):1508-21. PMID: 27621186.
    Citations: 7     Fields:    Translation:AnimalsCells
  29. Lee SH, Zabolotny JM, Huang H, Lee H, Kim YB. Insulin in the nervous system and the mind: Functions in metabolism, memory, and mood. Mol Metab. 2016 Aug; 5(8):589-601. PMID: 27656397.
    Citations: 35     Fields:    
  30. Rhee M, Lee SH, Kim JW, Ham DS, Park HS, Yang HK, Shin JY, Cho JH, Kim YB, Youn BS, Sul HS, Yoon KH. Preadipocyte factor 1 induces pancreatic ductal cell differentiation into insulin-producing cells. Sci Rep. 2016 Apr 05; 6:23960. PMID: 27044861.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  31. Kang MC, Kang N, Kim SY, Lima IS, Ko SC, Kim YT, Kim YB, Jeung HD, Choi KS, Jeon YJ. Popular edible seaweed, Gelidium amansii prevents against diet-induced obesity. Food Chem Toxicol. 2016 Apr; 90:181-7. PMID: 26911551.
    Citations: 21     Fields:    Translation:AnimalsCells
  32. Kang MC, Kang N, Ko SC, Kim YB, Jeon YJ. Anti-obesity effects of seaweeds of Jeju Island on the differentiation of 3T3-L1 preadipocytes and obese mice fed a high-fat diet. Food Chem Toxicol. 2016 Apr; 90:36-44. PMID: 26845612.
    Citations: 31     Fields:    Translation:AnimalsCells
  33. Moon PG, Lee JE, Cho YE, Lee SJ, Jung JH, Chae YS, Bae HI, Kim YB, Kim IS, Park HY, Baek MC. Identification of Developmental Endothelial Locus-1 on Circulating Extracellular Vesicles as a Novel Biomarker for Early Breast Cancer Detection. Clin Cancer Res. 2016 Apr 01; 22(7):1757-66. PMID: 26603257.
    Citations: 59     Fields:    Translation:HumansCells
  34. Lee JE, Moon PG, Cho YE, Kim YB, Kim IS, Park H, Baek MC. Identification of EDIL3 on extracellular vesicles involved in breast cancer cell invasion. J Proteomics. 2016 Jan 10; 131:17-28. PMID: 26463135.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  35. Lim S, Lee KS, Lee JE, Park HS, Kim KM, Moon JH, Choi SH, Park KS, Kim YB, Jang HC. Effect of a new PPAR-gamma agonist, lobeglitazone, on neointimal formation after balloon injury in rats and the development of atherosclerosis. Atherosclerosis. 2015 Nov; 243(1):107-19. PMID: 26363808.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  36. Kim KM, Lee KS, Lee GY, Jin H, Durrance ES, Park HS, Choi SH, Park KS, Kim YB, Jang HC, Lim S. Anti-diabetic efficacy of KICG1338, a novel glycogen synthase kinase-3ß inhibitor, and its molecular characterization in animal models of type 2 diabetes and insulin resistance. Mol Cell Endocrinol. 2015 Jul 05; 409:1-10. PMID: 25802191.
    Citations: 13     Fields:    Translation:Animals
  37. Koo YD, Choi JW, Kim M, Chae S, Ahn BY, Kim M, Oh BC, Hwang D, Seol JH, Kim YB, Park YJ, Chung SS, Park KS. SUMO-Specific Protease 2 (SENP2) Is an Important Regulator of Fatty Acid Metabolism in Skeletal Muscle. Diabetes. 2015 Jul; 64(7):2420-31. PMID: 25784542.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  38. Dagon Y, Mantzoros C, Kim YB. Exercising insulin sensitivity: AMPK turns on autophagy! Metabolism. 2015 Jun; 64(6):655-7. PMID: 25819737.
    Citations: 3     Fields:    Translation:Animals
  39. Zandi S, Nakao S, Chun KH, Fiorina P, Sun D, Arita R, Zhao M, Kim E, Schueller O, Campbell S, Taher M, Melhorn MI, Schering A, Gatti F, Tezza S, Xie F, Vergani A, Yoshida S, Ishikawa K, Yamaguchi M, Sasaki F, Schmidt-Ullrich R, Hata Y, Enaida H, Yuzawa M, Yokomizo T, Kim YB, Sweetnam P, Ishibashi T, Hafezi-Moghadam A. ROCK-isoform-specific polarization of macrophages associated with age-related macular degeneration. Cell Rep. 2015 Feb 24; 10(7):1173-86. PMID: 25704819.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  40. Byun K, Gil SY, Namkoong C, Youn BS, Huang H, Shin MS, Kang GM, Kim HK, Lee B, Kim YB, Kim MS. Clusterin/ApoJ enhances central leptin signaling through Lrp2-mediated endocytosis. EMBO Rep. 2014 Jul; 15(7):801-8. PMID: 24825475.
    Citations: 19     Fields:    Translation:AnimalsCells
  41. Macedo MP, Lima IS, Gaspar JM, Afonso RA, Patarrão RS, Kim YB, Ribeiro RT. Risk of postprandial insulin resistance: the liver/vagus rapport. Rev Endocr Metab Disord. 2014 Mar; 15(1):67-77. PMID: 24174131.
    Citations: 7     Fields:    Translation:HumansAnimals
  42. Giménez-Cassina A, Garcia-Haro L, Choi CS, Osundiji MA, Lane EA, Huang H, Yildirim MA, Szlyk B, Fisher JK, Polak K, Patton E, Wiwczar J, Godes M, Lee DH, Robertson K, Kim S, Kulkarni A, Distefano A, Samuel V, Cline G, Kim YB, Shulman GI, Danial NN. Regulation of hepatic energy metabolism and gluconeogenesis by BAD. Cell Metab. 2014 Feb 04; 19(2):272-84. PMID: 24506868.
    Citations: 34     Fields:    Translation:AnimalsCells
  43. Dong H, Huang H, Yun X, Kim DS, Yue Y, Wu H, Sutter A, Chavin KD, Otterbein LE, Adams DB, Kim YB, Wang H. Bilirubin increases insulin sensitivity in leptin-receptor deficient and diet-induced obese mice through suppression of ER stress and chronic inflammation. Endocrinology. 2014 Mar; 155(3):818-28. PMID: 24424052.
    Citations: 48     Fields:    Translation:AnimalsCells
  44. Lee SH, Huang H, Choi K, Lee DH, Shi J, Liu T, Chun KH, Seo JA, Lima IS, Zabolotny JM, Wei L, Kim YB. ROCK1 isoform-specific deletion reveals a role for diet-induced insulin resistance. Am J Physiol Endocrinol Metab. 2014 Feb; 306(3):E332-43. PMID: 24326423.
    Citations: 25     Fields:    Translation:AnimalsCells
  45. Huang H, Lee DH, Zabolotny JM, Kim YB. Metabolic actions of Rho-kinase in periphery and brain. Trends Endocrinol Metab. 2013 Oct; 24(10):506-14. PMID: 23938132.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  46. Huang H, Lee SH, Ye C, Lima IS, Oh BC, Lowell BB, Zabolotny JM, Kim YB. ROCK1 in AgRP neurons regulates energy expenditure and locomotor activity in male mice. Endocrinology. 2013 Oct; 154(10):3660-70. PMID: 23885017.
    Citations: 17     Fields:    Translation:AnimalsCells
  47. Lee Y, Lim S, Hong ES, Kim JH, Moon MK, Chun EJ, Choi SI, Kim YB, Park YJ, Park KS, Jang HC, Choi SH. Serum FGF21 concentration is associated with hypertriglyceridaemia, hyperinsulinaemia and pericardial fat accumulation, independently of obesity, but not with current coronary artery status. Clin Endocrinol (Oxf). 2014 Jan; 80(1):57-64. PMID: 23278761.
    Citations: 28     Fields:    Translation:Humans
  48. Manabe Y, Gollisch KS, Holton L, Kim YB, Brandauer J, Fujii NL, Hirshman MF, Goodyear LJ. Exercise training-induced adaptations associated with increases in skeletal muscle glycogen content. FEBS J. 2013 Feb; 280(3):916-26. PMID: 23206309.
    Citations: 15     Fields:    Translation:Animals
  49. Gil SY, Youn BS, Byun K, Huang H, Namkoong C, Jang PG, Lee JY, Jo YH, Kang GM, Kim HK, Shin MS, Pietrzik CU, Lee B, Kim YB, Kim MS. Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway. Nat Commun. 2013; 4:1862. PMID: 23673647.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  50. Gurkar AU, Chu K, Raj L, Bouley R, Lee SH, Kim YB, Dunn SE, Mandinova A, Lee SW. Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. Nat Commun. 2013; 4:2189. PMID: 23877263.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  51. Huang H, Kong D, Byun KH, Ye C, Koda S, Lee DH, Oh BC, Lee SW, Lee B, Zabolotny JM, Kim MS, Bjørbæk C, Lowell BB, Kim YB. Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling. Nat Neurosci. 2012 Oct; 15(10):1391-8. PMID: 22941110.
    Citations: 49     Fields:    Translation:AnimalsCells
  52. Chu SH, Park JH, Lee MK, Jekal Y, Ahn KY, Chung JY, Lee DH, Kim ES, Naruse M, Im JA, Kong ID, Kong D, Chung CH, Lee JW, Chung KM, Kim YB, Jeon JY. The association between pentraxin 3 and insulin resistance in obese children at baseline and after physical activity intervention. Clin Chim Acta. 2012 Oct 09; 413(19-20):1430-7. PMID: 22687644.
    Citations: 11     Fields:    Translation:Humans
  53. Cha JY, Kim YB. Sulfated oxysterol 25HC3S as a therapeutic target of non-alcoholic fatty liver disease. Metabolism. 2012 Aug; 61(8):1055-7. PMID: 22592130.
    Citations: 2     Fields:    Translation:AnimalsCells
  54. Lim S, Choi SH, Shin H, Cho BJ, Park HS, Ahn BY, Kang SM, Yoon JW, Jang HC, Kim YB, Park KS. Effect of a dipeptidyl peptidase-IV inhibitor, des-fluoro-sitagliptin, on neointimal formation after balloon injury in rats. PLoS One. 2012; 7(4):e35007. PMID: 22493727.
    Citations: 22     Fields:    Translation:AnimalsCells
  55. Chun KH, Araki K, Jee Y, Lee DH, Oh BC, Huang H, Park KS, Lee SW, Zabolotny JM, Kim YB. Regulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerization. Endocrinology. 2012 Apr; 153(4):1649-62. PMID: 22355071.
    Citations: 37     Fields:    Translation:AnimalsCells
  56. Yoon JW, Cho BJ, Park HS, Kang SM, Choi SH, Jang HC, Shin H, Lee MJ, Kim YB, Park KS, Lim S. Differential effects of trimetazidine on vascular smooth muscle cell and endothelial cell in response to carotid artery balloon injury in diabetic rats. Int J Cardiol. 2013 Jul 15; 167(1):126-33. PMID: 22240760.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  57. Lee DH, Huang H, Choi K, Mantzoros C, Kim YB. Selective PPAR? modulator INT131 normalizes insulin signaling defects and improves bone mass in diet-induced obese mice. Am J Physiol Endocrinol Metab. 2012 Mar 01; 302(5):E552-60. PMID: 22215652.
    Citations: 15     Fields:    Translation:AnimalsCells
  58. Jeon JY, Kim YB. Is perilipin critical in fat utilization during exercise? Metabolism. 2012 Mar; 61(3):291-2. PMID: 22209667.
    Citations:    Fields:    Translation:Animals
  59. Lee SH, Mantzoros C, Kim YB. Resveratrol: is selectivity opening the key to therapeutic effects? Metabolism. 2012 Mar; 61(3):289-90. PMID: 22075269.
    Citations: 3     Fields:    Translation:AnimalsCells
  60. Lim S, Choi SH, Koo BK, Kang SM, Yoon JW, Jang HC, Choi SM, Lee MG, Lee W, Shin H, Kim YB, Lee HK, Park KS. Effects of aerobic exercise training on C1q tumor necrosis factor a-related protein isoform 5 (myonectin): association with insulin resistance and mitochondrial DNA density in women. J Clin Endocrinol Metab. 2012 Jan; 97(1):E88-93. PMID: 22031510.
    Citations: 20     Fields:    Translation:Humans
  61. Shinozaki S, Choi CS, Shimizu N, Yamada M, Kim M, Zhang T, Shiota G, Dong HH, Kim YB, Kaneki M. Liver-specific inducible nitric-oxide synthase expression is sufficient to cause hepatic insulin resistance and mild hyperglycemia in mice. J Biol Chem. 2011 Oct 07; 286(40):34959-75. PMID: 21846719.
    Citations: 28     Fields:    Translation:AnimalsCells
  62. Shin HJ, Park YH, Kim SU, Moon HB, Park DS, Han YH, Lee CH, Lee DS, Song IS, Lee DH, Kim M, Kim NS, Kim DG, Kim JM, Kim SK, Kim YN, Kim SS, Choi CS, Kim YB, Yu DY. Hepatitis B virus X protein regulates hepatic glucose homeostasis via activation of inducible nitric oxide synthase. J Biol Chem. 2011 Aug 26; 286(34):29872-81. PMID: 21690090.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  63. Lim S, Yoon JW, Kang SM, Choi SH, Cho BJ, Kim M, Park HS, Cho HJ, Shin H, Kim YB, Kim HS, Jang HC, Park KS. EGb761, a Ginkgo biloba extract, is effective against atherosclerosis in vitro, and in a rat model of type 2 diabetes. PLoS One. 2011; 6(6):e20301. PMID: 21655098.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  64. Aronis KN, Kim YB, Mantzoros CS. Clusterin (apolipoprotein J): wither link with diabetes and cardiometabolic risk? Metabolism. 2011 Jun; 60(6):747-8. PMID: 21333309.
    Citations: 3     Fields:    Translation:Humans
  65. Lim S, Moon MK, Shin H, Kim TH, Cho BJ, Kim M, Park HS, Choi SH, Ko SH, Chung MH, Lee IK, Jang HC, Kim YB, Park KS. Effect of S-adenosylmethionine on neointimal formation after balloon injury in obese diabetic rats. Cardiovasc Res. 2011 May 01; 90(2):383-93. PMID: 21245056.
    Citations: 8     Fields:    Translation:AnimalsCells
  66. Chun KH, Choi KD, Lee DH, Jung Y, Henry RR, Ciaraldi TP, Kim YB. In vivo activation of ROCK1 by insulin is impaired in skeletal muscle of humans with type 2 diabetes. Am J Physiol Endocrinol Metab. 2011 Mar; 300(3):E536-42. PMID: 21189360.
    Citations: 26     Fields:    Translation:HumansCells
  67. Kim HK, Youn BS, Shin MS, Namkoong C, Park KH, Baik JH, Kim JB, Park JY, Lee KU, Kim YB, Kim MS. Hypothalamic Angptl4/Fiaf is a novel regulator of food intake and body weight. Diabetes. 2010 Nov; 59(11):2772-80. PMID: 20798332.
    Citations: 43     Fields:    Translation:Animals
  68. Choi K, Kim YB. Molecular mechanism of insulin resistance in obesity and type 2 diabetes. Korean J Intern Med. 2010 Jun; 25(2):119-29. PMID: 20526383.
    Citations: 65     Fields:    Translation:HumansCells
  69. Han SH, Choi SH, Cho BJ, Lee Y, Lim S, Park YJ, Moon MK, Lee HK, Kang SW, Han DS, Kim YB, Jang HC, Park KS. Serum fibroblast growth factor-21 concentration is associated with residual renal function and insulin resistance in end-stage renal disease patients receiving long-term peritoneal dialysis. Metabolism. 2010 Nov; 59(11):1656-62. PMID: 20423749.
    Citations: 28     Fields:    Translation:Humans
  70. Chung SS, Ahn BY, Kim M, Choi HH, Park HS, Kang S, Park SG, Kim YB, Cho YM, Lee HK, Chung CH, Park KS. Control of adipogenesis by the SUMO-specific protease SENP2. Mol Cell Biol. 2010 May; 30(9):2135-46. PMID: 20194620.
    Citations: 23     Fields:    Translation:AnimalsCells
  71. Jang PG, Namkoong C, Kang GM, Hur MW, Kim SW, Kim GH, Kang Y, Jeon MJ, Kim EH, Lee MS, Karin M, Baik JH, Park JY, Lee KU, Kim YB, Kim MS. NF-kappaB activation in hypothalamic pro-opiomelanocortin neurons is essential in illness- and leptin-induced anorexia. J Biol Chem. 2010 Mar 26; 285(13):9706-9715. PMID: 20097762.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  72. Shiuchi T, Haque MS, Okamoto S, Inoue T, Kageyama H, Lee S, Toda C, Suzuki A, Bachman ES, Kim YB, Sakurai T, Yanagisawa M, Shioda S, Imoto K, Minokoshi Y. Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system. Cell Metab. 2009 Dec; 10(6):466-80. PMID: 19945404.
    Citations: 80     Fields:    Translation:Animals
  73. Kienesberger PC, Lee D, Pulinilkunnil T, Brenner DS, Cai L, Magnes C, Koefeler HC, Streith IE, Rechberger GN, Haemmerle G, Flier JS, Zechner R, Kim YB, Kershaw EE. Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling. J Biol Chem. 2009 Oct 30; 284(44):30218-29. PMID: 19723629.
    Citations: 65     Fields:    Translation:AnimalsCells
  74. Lim S, Yoon JW, Choi SH, Park YJ, Lee JJ, Park JH, Lee SB, Kim KW, Lim JY, Kim YB, Park KS, Lee HK, Cho SI, Jang HC. Combined impact of adiponectin and retinol-binding protein 4 on metabolic syndrome in elderly people: the Korean Longitudinal Study on Health and Aging. Obesity (Silver Spring). 2010 Apr; 18(4):826-32. PMID: 19661959.
    Citations: 18     Fields:    Translation:Humans
  75. Park HJ, Zhang Y, Du C, Welzig CM, Madias C, Aronovitz MJ, Georgescu SP, Naggar I, Wang B, Kim YB, Blaustein RO, Karas RH, Liao R, Mathews CE, Galper JB. Role of SREBP-1 in the development of parasympathetic dysfunction in the hearts of type 1 diabetic Akita mice. Circ Res. 2009 Jul 31; 105(3):287-94. PMID: 19423844.
    Citations: 17     Fields:    Translation:AnimalsCells
  76. Lee DH, Shi J, Jeoung NH, Kim MS, Zabolotny JM, Lee SW, White MF, Wei L, Kim YB. Targeted disruption of ROCK1 causes insulin resistance in vivo. J Biol Chem. 2009 May 01; 284(18):11776-80. PMID: 19276091.
    Citations: 65     Fields:    Translation:AnimalsCells
  77. Lim S, Yoon JW, Choi SH, Cho BJ, Kim JT, Chang HS, Park HS, Park KS, Lee HK, Kim YB, Jang HC. Effect of ginsam, a vinegar extract from Panax ginseng, on body weight and glucose homeostasis in an obese insulin-resistant rat model. Metabolism. 2009 Jan; 58(1):8-15. PMID: 19059525.
    Citations: 14     Fields:    Translation:AnimalsCells
  78. Ongusaha PP, Qi HH, Raj L, Kim YB, Aaronson SA, Davis RJ, Shi Y, Liao JK, Lee SW. Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage. Sci Signal. 2008 Nov 25; 1(47):ra14. PMID: 19036714.
    Citations: 26     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  79. Lim S, Son KR, Song IC, Park HS, Jin CJ, Jang HC, Park KS, Kim YB, Lee HK. Fat in liver/muscle correlates more strongly with insulin sensitivity in rats than abdominal fat. Obesity (Silver Spring). 2009 Jan; 17(1):188-95. PMID: 18948962.
    Citations: 13     Fields:    Translation:Animals
  80. Villena JA, Choi CS, Wang Y, Kim S, Hwang YJ, Kim YB, Cline G, Shulman GI, Sul HS. Resistance to high-fat diet-induced obesity but exacerbated insulin resistance in mice overexpressing preadipocyte factor-1 (Pref-1): a new model of partial lipodystrophy. Diabetes. 2008 Dec; 57(12):3258-66. PMID: 18835937.
    Citations: 37     Fields:    Translation:Animals
  81. Choi SH, Kwak SH, Youn BS, Lim S, Park YJ, Lee H, Lee N, Cho YM, Lee HK, Kim YB, Park KS, Jang HC. High plasma retinol binding protein-4 and low plasma adiponectin concentrations are associated with severity of glucose intolerance in women with previous gestational diabetes mellitus. J Clin Endocrinol Metab. 2008 Aug; 93(8):3142-8. PMID: 18492757.
    Citations: 23     Fields:    Translation:Humans
  82. Lim S, Choi SH, Jeong IK, Kim JH, Moon MK, Park KS, Lee HK, Kim YB, Jang HC. Insulin-sensitizing effects of exercise on adiponectin and retinol-binding protein-4 concentrations in young and middle-aged women. J Clin Endocrinol Metab. 2008 Jun; 93(6):2263-8. PMID: 18334592.
    Citations: 42     Fields:    Translation:HumansCTClinical Trials
  83. Zabolotny JM, Kim YB, Welsh LA, Kershaw EE, Neel BG, Kahn BB. Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo. J Biol Chem. 2008 May 23; 283(21):14230-41. PMID: 18281274.
    Citations: 142     Fields:    Translation:AnimalsCells
  84. Handschin C, Choi CS, Chin S, Kim S, Kawamori D, Kurpad AJ, Neubauer N, Hu J, Mootha VK, Kim YB, Kulkarni RN, Shulman GI, Spiegelman BM. Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk. J Clin Invest. 2007 Nov; 117(11):3463-74. PMID: 17932564.
    Citations: 175     Fields:    Translation:HumansAnimalsCells
  85. Zabolotny JM, Kim YB. Silencing insulin resistance through SIRT1. Cell Metab. 2007 Oct; 6(4):247-9. PMID: 17908551.
    Citations: 8     Fields:    Translation:HumansCells
  86. Xue B, Kim YB, Lee A, Toschi E, Bonner-Weir S, Kahn CR, Neel BG, Kahn BB. Protein-tyrosine phosphatase 1B deficiency reduces insulin resistance and the diabetic phenotype in mice with polygenic insulin resistance. J Biol Chem. 2007 Aug 17; 282(33):23829-40. PMID: 17545163.
    Citations: 25     Fields:    Translation:AnimalsCells
  87. Ongusaha PP, Kim HG, Boswell SA, Ridley AJ, Der CJ, Dotto GP, Kim YB, Aaronson SA, Lee SW. RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress. Curr Biol. 2006 Dec 19; 16(24):2466-72. PMID: 17174923.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  88. Vianna CR, Huntgeburth M, Coppari R, Choi CS, Lin J, Krauss S, Barbatelli G, Tzameli I, Kim YB, Cinti S, Shulman GI, Spiegelman BM, Lowell BB. Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance. Cell Metab. 2006 Dec; 4(6):453-64. PMID: 17141629.
    Citations: 85     Fields:    Translation:AnimalsCells
  89. Kim MS, Pak YK, Jang PG, Namkoong C, Choi YS, Won JC, Kim KS, Kim SW, Kim HS, Park JY, Kim YB, Lee KU. Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis. Nat Neurosci. 2006 Jul; 9(7):901-6. PMID: 16783365.
    Citations: 136     Fields:    Translation:HumansAnimalsCells
  90. Aschenbach WG, Ho RC, Sakamoto K, Fujii N, Li Y, Kim YB, Hirshman MF, Goodyear LJ. Regulation of dishevelled and beta-catenin in rat skeletal muscle: an alternative exercise-induced GSK-3beta signaling pathway. Am J Physiol Endocrinol Metab. 2006 Jul; 291(1):E152-8. PMID: 16478782.
    Citations: 22     Fields:    Translation:AnimalsCells
  91. Park SY, Cho YR, Kim HJ, Higashimori T, Danton C, Lee MK, Dey A, Rothermel B, Kim YB, Kalinowski A, Russell KS, Kim JK. Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice. Diabetes. 2005 Dec; 54(12):3530-40. PMID: 16306372.
    Citations: 132     Fields:    Translation:Animals
  92. Kim YB, Peroni OD, Aschenbach WG, Minokoshi Y, Kotani K, Zisman A, Kahn CR, Goodyear LJ, Kahn BB. Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism. Mol Cell Biol. 2005 Nov; 25(21):9713-23. PMID: 16227617.
    Citations: 22     Fields:    Translation:AnimalsCells
  93. Park SY, Cho YR, Finck BN, Kim HJ, Higashimori T, Hong EG, Lee MK, Danton C, Deshmukh S, Cline GW, Wu JJ, Bennett AM, Rothermel B, Kalinowski A, Russell KS, Kim YB, Kelly DP, Kim JK. Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver. Diabetes. 2005 Sep; 54(9):2514-24. PMID: 16123338.
    Citations: 50     Fields:    Translation:AnimalsCells
  94. Furukawa N, Ongusaha P, Jahng WJ, Araki K, Choi CS, Kim HJ, Lee YH, Kaibuchi K, Kahn BB, Masuzaki H, Kim JK, Lee SW, Kim YB. Role of Rho-kinase in regulation of insulin action and glucose homeostasis. Cell Metab. 2005 Aug; 2(2):119-29. PMID: 16098829.
    Citations: 77     Fields:    Translation:HumansAnimalsCells
  95. Haj FG, Zabolotny JM, Kim YB, Kahn BB, Neel BG. Liver-specific protein-tyrosine phosphatase 1B (PTP1B) re-expression alters glucose homeostasis of PTP1B-/-mice. J Biol Chem. 2005 Apr 15; 280(15):15038-46. PMID: 15699041.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  96. Chan JL, Moschos SJ, Bullen J, Heist K, Li X, Kim YB, Kahn BB, Mantzoros CS. Recombinant methionyl human leptin administration activates signal transducer and activator of transcription 3 signaling in peripheral blood mononuclear cells in vivo and regulates soluble tumor necrosis factor-alpha receptor levels in humans with relative leptin deficiency. J Clin Endocrinol Metab. 2005 Mar; 90(3):1625-31. PMID: 15613409.
    Citations: 21     Fields:    Translation:HumansCellsCTClinical Trials
  97. Corbould A, Kim YB, Youngren JF, Pender C, Kahn BB, Lee A, Dunaif A. Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling. Am J Physiol Endocrinol Metab. 2005 May; 288(5):E1047-54. PMID: 15613682.
    Citations: 69     Fields:    Translation:HumansCells
  98. Kim MS, Yoon CY, Jang PG, Park YJ, Shin CS, Park HS, Ryu JW, Pak YK, Park JY, Lee KU, Kim SY, Lee HK, Kim YB, Park KS. The mitogenic and antiapoptotic actions of ghrelin in 3T3-L1 adipocytes. Mol Endocrinol. 2004 Sep; 18(9):2291-301. PMID: 15178745.
    Citations: 54     Fields:    Translation:AnimalsCells
  99. Lamia KA, Peroni OD, Kim YB, Rameh LE, Kahn BB, Cantley LC. Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta-/- mice. Mol Cell Biol. 2004 Jun; 24(11):5080-7. PMID: 15143198.
    Citations: 47     Fields:    Translation:Animals
  100. Kim HJ, Higashimori T, Park SY, Choi H, Dong J, Kim YJ, Noh HL, Cho YR, Cline G, Kim YB, Kim JK. Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo. Diabetes. 2004 Apr; 53(4):1060-7. PMID: 15047622.
    Citations: 180     Fields:    Translation:AnimalsCells
  101. Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, Mu J, Foufelle F, Ferré P, Birnbaum MJ, Stuck BJ, Kahn BB. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature. 2004 Apr 01; 428(6982):569-74. PMID: 15058305.
    Citations: 532     Fields:    Translation:Animals
  102. Zabolotny JM, Haj FG, Kim YB, Kim HJ, Shulman GI, Kim JK, Neel BG, Kahn BB. Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action. J Biol Chem. 2004 Jun 04; 279(23):24844-51. PMID: 15031294.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  103. Kim YB, Kotani K, Ciaraldi TP, Henry RR, Kahn BB. Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction. Diabetes. 2003 Aug; 52(8):1935-42. PMID: 12882908.
    Citations: 59     Fields:    Translation:HumansCells
  104. Choi CS, Kim YB, Lee FN, Zabolotny JM, Kahn BB, Youn JH. Lactate induces insulin resistance in skeletal muscle by suppressing glycolysis and impairing insulin signaling. Am J Physiol Endocrinol Metab. 2002 Aug; 283(2):E233-40. PMID: 12110527.
    Citations: 34     Fields:    Translation:AnimalsCells
  105. Kim YB, Shulman GI, Kahn BB. Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C lambda /zeta but not on glycogen synthase kinase-3. J Biol Chem. 2002 Sep 06; 277(36):32915-22. PMID: 12095990.
    Citations: 29     Fields:    Translation:AnimalsCells
  106. Zabolotny JM, Bence-Hanulec KK, Stricker-Krongrad A, Haj F, Wang Y, Minokoshi Y, Kim YB, Elmquist JK, Tartaglia LA, Kahn BB, Neel BG. PTP1B regulates leptin signal transduction in vivo. Dev Cell. 2002 Apr; 2(4):489-95. PMID: 11970898.
    Citations: 240     Fields:    Translation:AnimalsCells
  107. Kim YB, Ciaraldi TP, Kong A, Kim D, Chu N, Mohideen P, Mudaliar S, Henry RR, Kahn BB. Troglitazone but not metformin restores insulin-stimulated phosphoinositide 3-kinase activity and increases p110beta protein levels in skeletal muscle of type 2 diabetic subjects. Diabetes. 2002 Feb; 51(2):443-8. PMID: 11812753.
    Citations: 39     Fields:    Translation:HumansCTClinical Trials
  108. Minokoshi Y, Kim YB, Peroni OD, Fryer LG, Müller C, Carling D, Kahn BB. Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature. 2002 Jan 17; 415(6869):339-43. PMID: 11797013.
    Citations: 543     Fields:    Translation:AnimalsCells
  109. Tanner CJ, Koves TR, Cortright RL, Pories WJ, Kim YB, Kahn BB, Dohm GL, Houmard JA. Effect of short-term exercise training on insulin-stimulated PI 3-kinase activity in middle-aged men. Am J Physiol Endocrinol Metab. 2002 Jan; 282(1):E147-53. PMID: 11739095.
    Citations: 15     Fields:    Translation:Humans
  110. Zhang CY, Baffy G, Perret P, Krauss S, Peroni O, Grujic D, Hagen T, Vidal-Puig AJ, Boss O, Kim YB, Zheng XX, Wheeler MB, Shulman GI, Chan CB, Lowell BB. Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. Cell. 2001 Jun 15; 105(6):745-55. PMID: 11440717.
    Citations: 281     Fields:    Translation:HumansAnimals
  111. Zabolotny JM, Kim YB, Peroni OD, Kim JK, Pani MA, Boss O, Klaman LD, Kamatkar S, Shulman GI, Kahn BB, Neel BG. Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance. Proc Natl Acad Sci U S A. 2001 Apr 24; 98(9):5187-92. PMID: 11309481.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  112. Abel ED, Peroni O, Kim JK, Kim YB, Boss O, Hadro E, Minnemann T, Shulman GI, Kahn BB. Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature. 2001 Feb 08; 409(6821):729-33. PMID: 11217863.
    Citations: 385     Fields:    Translation:AnimalsCells
  113. Huppertz C, Fischer BM, Kim YB, Kotani K, Vidal-Puig A, Slieker LJ, Sloop KW, Lowell BB, Kahn BB. Uncoupling protein 3 (UCP3) stimulates glucose uptake in muscle cells through a phosphoinositide 3-kinase-dependent mechanism. J Biol Chem. 2001 Apr 20; 276(16):12520-9. PMID: 11278970.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  114. Klaman LD, Boss O, Peroni OD, Kim JK, Martino JL, Zabolotny JM, Moghal N, Lubkin M, Kim YB, Sharpe AH, Stricker-Krongrad A, Shulman GI, Neel BG, Kahn BB. Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice. Mol Cell Biol. 2000 Aug; 20(15):5479-89. PMID: 10891488.
    Citations: 334     Fields:    Translation:Animals
  115. Kim YB, Uotani S, Pierroz DD, Flier JS, Kahn BB. In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin. Endocrinology. 2000 Jul; 141(7):2328-39. PMID: 10875232.
    Citations: 59     Fields:    Translation:AnimalsCells
  116. Venable CL, Frevert EU, Kim YB, Fischer BM, Kamatkar S, Neel BG, Kahn BB. Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation. J Biol Chem. 2000 Jun 16; 275(24):18318-26. PMID: 10751417.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  117. Kim YB, Peroni OD, Franke TF, Kahn BB. Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats. Diabetes. 2000 May; 49(5):847-56. PMID: 10905496.
    Citations: 32     Fields:    Translation:AnimalsCells
  118. Kim YB, Nikoulina SE, Ciaraldi TP, Henry RR, Kahn BB. Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes. J Clin Invest. 1999 Sep; 104(6):733-41. PMID: 10491408.
    Citations: 120     Fields:    Translation:HumansCells
  119. Kim YB, Zhu JS, Zierath JR, Shen HQ, Baron AD, Kahn BB. Glucosamine infusion in rats rapidly impairs insulin stimulation of phosphoinositide 3-kinase but does not alter activation of Akt/protein kinase B in skeletal muscle. Diabetes. 1999 Feb; 48(2):310-20. PMID: 10334307.
    Citations: 12     Fields:    Translation:AnimalsCells
  120. Kim YB, Inoue T, Nakajima R, Shirai-Morishita Y, Tokuyama K, Suzuki M. Effect of long-term exercise on gene expression of insulin signaling pathway intermediates in skeletal muscle. Biochem Biophys Res Commun. 1999 Jan 27; 254(3):720-7. PMID: 9920808.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  121. Kim YB, Nakajima R, Matsuo T, Inoue T, Sekine T, Komuro M, Tamura T, Tokuyama K, Suzuki M. Gene expression of insulin signal-transduction pathway intermediates is lower in rats fed a beef tallow diet than in rats fed a safflower oil diet. Metabolism. 1996 Sep; 45(9):1080-8. PMID: 8781294.
    Citations: 2     Fields:    Translation:AnimalsCells
  122. Iwashita S, Kim YB, Miyamoto H, Komuro M, Tokuyama K, Suzuki M. Diurnal rhythm of plasma insulin and glucose in rats made obese by a high fat diet. Horm Metab Res. 1996 Apr; 28(4):199-201. PMID: 8740197.
    Citations:    Fields:    Translation:Animals
  123. Kim Y, Inoue T, Nakajima R, Nakae K, Tamura T, Tokuyama K, Suzuki M. Effects of endurance training on gene expression of insulin signal transduction pathway. Biochem Biophys Res Commun. 1995 May 25; 210(3):766-73. PMID: 7763251.
    Citations: 5     Fields:    Translation:AnimalsCells
  124. Kim Y, Iwashita S, Tamura T, Tokuyama K, Suzuki M. Effect of high-fat diet on the gene expression of pancreatic GLUT2 and glucokinase in rats. Biochem Biophys Res Commun. 1995 Mar 28; 208(3):1092-8. PMID: 7702608.
    Citations: 10     Fields:    Translation:Animals
  125. Kim Y, Tamura T, Iwashita S, Tokuyama K, Suzuki M. Effect of high-fat diet on gene expression of GLUT4 and insulin receptor in soleus muscle. Biochem Biophys Res Commun. 1994 Jul 15; 202(1):519-26. PMID: 8037757.
    Citations: 6     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.