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Karagianni F, Njauw CN, Kypreou KP, Stergiopoulou A, Plaka M, Polydorou D, Chasapi V, Pappas L, Stratigos I, Champsas G, Panagiotou P, Gogas H, Evangelou E, Tsao H, Stratigos A, Stefanaki I. CDKN2A/CDK4 Status in Greek Patients with Familial Melanoma and Association with Clinico-epidemiological Parameters. Acta Derm Venereol. 2018 May 18. PMID: 29774366.
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Klebanov N, Reddy BY, Husain S, Silvers DN, Grossman ME, Tsao H. Cutaneous Presentation of Mesothelioma With a Sarcomatoid Transformation. Am J Dermatopathol. 2018 May; 40(5):378-382. PMID: 29059099.
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Bartenstein DW, Kelleher CM, Friedmann AM, Duncan LM, Tsao H, Sober AJ, Hawryluk EB. Contrasting features of childhood and adolescent melanomas. Pediatr Dermatol. 2018 May; 35(3):354-360. PMID: 29569376.
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Eliades P, Abraham BJ, Ji Z, Miller DM, Christensen CL, Kwiatkowski N, Kumar R, Njauw CN, Taylor M, Miao B, Zhang T, Wong KK, Gray NS, Young RA, Tsao H. High MITF Expression Is Associated with Super-Enhancers and Suppressed by CDK7 Inhibition in Melanoma. J Invest Dermatol. 2018 Jul; 138(7):1582-1590. PMID: 29408204.
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Artomov M, Stratigos AJ, Kim I, Kumar R, Lauss M, Reddy BY, Miao B, Daniela Robles-Espinoza C, Sankar A, Njauw CN, Shannon K, Gragoudas ES, Marie Lane A, Iyer V, Newton-Bishop JA, Timothy Bishop D, Holland EA, Mann GJ, Singh T, Daly MJ, Tsao H. Rare Variant, Gene-Based Association Study of Hereditary Melanoma Using Whole-Exome Sequencing. J Natl Cancer Inst. 2017 Dec 01; 109(12). PMID: 29522175.
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Haugh AM, Njauw CN, Bubley JA, Verzì AE, Zhang B, Kudalkar E, VandenBoom T, Walton K, Swick BL, Kumar R, Rana HQ, Cochrane S, McCormick SR, Shea CR, Tsao H, Gerami P. Genotypic and Phenotypic Features of BAP1 Cancer Syndrome: A Report of 8 New Families and Review of Cases in the Literature. JAMA Dermatol. 2017 Oct 01; 153(10):999-1006. PMID: 28793149.
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Reddy BY, Miller DM, Tsao H. Somatic driver mutations in melanoma. Cancer. 2017 Jun 01; 123(S11):2104-2117. PMID: 28543693.
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Tsao H. Introduction to JID's Landmarks in the Molecular Revolution. J Invest Dermatol. 2017 May; 137(5):996. PMID: 28411838.
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Roh MR, Eliades P, Gupta S, Grant-Kels JM, Tsao H. Cutaneous melanoma in women. Int J Womens Dermatol. 2017 Mar; 3(1 Suppl):S11-S15. PMID: 28492033.
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Tsao H, Fukunaga-Kalabis M, Herlyn M. Recent Advances in Melanoma and Melanocyte Biology. J Invest Dermatol. 2017 Mar; 137(3):557-560. PMID: 28089201.
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Torres A, Tsao H. Commentary: American Academy of Dermatology free skin cancer screening: 30 years of value. J Am Acad Dermatol. 2017 Jan; 76(1):181-182. PMID: 27986146.
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Roh MR, Park KH, Chung KY, Shin SJ, Rha SY, Tsao H. Telomerase reverse transcriptase (TERT) promoter mutations in Korean melanoma patients. Am J Cancer Res. 2017; 7(1):134-138. PMID: 28123854.
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Wang H, Osseiran S, Igras V, Nichols AJ, Roider EM, Pruessner J, Tsao H, Fisher DE, Evans CL. In vivo coherent Raman imaging of the melanomagenesis-associated pigment pheomelanin. Sci Rep. 2016 11 28; 6:37986. PMID: 27892516.
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Soura E, Stratigos AJ, Tsao H. Reply to: "The absence of multiple atypical nevi in germline CDKN2A mutations". J Am Acad Dermatol. 2016 10; 75(4):e159. PMID: 27646764.
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Eliades P, Tsao H. New Insights into the Molecular Distinction of Dysplastic Nevi and Common Melanocytic Nevi-Highlighting the Keratinocyte-Melanocyte Relationship. J Invest Dermatol. 2016 10; 136(10):1933-1935. PMID: 27664709.
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Ratushny V, Kraft S, Moschella SL, Duncan LM, Lawrence DP, Tsao H. A Symmetric Eczematous Eruption Harboring Thousands of Melanocytic Lesions. JAMA Dermatol. 2016 09 01; 152(9):1021-4. PMID: 27192392.
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Tsao H, Weinstock MA. Visual Inspection and the US Preventive Services Task Force Recommendation on Skin Cancer Screening. JAMA. 2016 Jul 26; 316(4):398-400. PMID: 27458944.
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Eliades P, Miller DM, Miao B, Kumar R, Taylor M, Buch S, Srinivasa SP, Flaherty KT, Tsao H. A novel multi-CDK inhibitor P1446A-05 restricts melanoma growth and produces synergistic effects in combination with MAPK pathway inhibitors. Cancer Biol Ther. 2016 07 02; 17(7):778-84. PMID: 26810603.
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Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, Atkins MB, Bosenberg MW, Dummer R, Gershenwald JE, Halpern AC, Herlyn D, Karakousis GC, Kirkwood JM, Krauthammer M, Lo RS, Long GV, McArthur G, Ribas A, Schuchter L, Sosman JA, Smalley KS, Steeg P, Thomas NE, Tsao H, Tueting T, Weeraratna A, Xu G, Lomax R, Martin A, Silverstein S, Turnham T, Ronai ZA. The state of melanoma: challenges and opportunities. Pigment Cell Melanoma Res. 2016 07; 29(4):404-16. PMID: 27087480.
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Wu JW, Turcotte R, Alt C, Runnels JM, Tsao H, Lin CP. Defining Clonal Color in Fluorescent Multi-Clonal Tracking. Sci Rep. 2016 Apr 13; 6:24303. PMID: 27073117; PMCID: PMC4829845.
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Soura E, Eliades PJ, Shannon K, Stratigos AJ, Tsao H. Hereditary melanoma: Update on syndromes and management: Emerging melanoma cancer complexes and genetic counseling. J Am Acad Dermatol. 2016 Mar; 74(3):411-20; quiz 421-2. PMID: 26892651; PMCID: PMC4761106 [Available on 03/01/17].
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Soura E, Eliades PJ, Shannon K, Stratigos AJ, Tsao H. Hereditary melanoma: Update on syndromes and management: Genetics of familial atypical multiple mole melanoma syndrome. J Am Acad Dermatol. 2016 Mar; 74(3):395-407; quiz 408-10. PMID: 26892650; PMCID: PMC4761105 [Available on 03/01/17].
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Roh MR, Gupta S, Park KH, Chung KY, Lauss M, Flaherty KT, Jönsson G, Rha SY, Tsao H. Promoter Methylation of PTEN Is a Significant Prognostic Factor in Melanoma Survival. J Invest Dermatol. 2016 05; 136(5):1002-11. PMID: 26854490.
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Roh MR, Eliades P, Gupta S, Tsao H. Genetics of melanocytic nevi. Pigment Cell Melanoma Res. 2015 Nov; 28(6):661-72. PMID: 26300491; PMCID: PMC4609613 [Available on 11/01/16].
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Gerami P, Yélamos O, Lee CY, Obregon R, Yazdan P, Sholl LM, Guitart GE, Njauw CN, Tsao H. Multiple Cutaneous Melanomas and Clinically Atypical Moles in a Patient With a Novel Germline BAP1 Mutation. JAMA Dermatol. 2015 Nov; 151(11):1235-9. PMID: 26154183.
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Gerami P, Tsao H. Concerns About Presence of a Wild-Type BAP1 Allele in Absence of Nuclear Protein Expression-Reply. JAMA Dermatol. 2015 Nov; 151(11):1266. PMID: 26559348.
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Tsao H, Begolka WS. Reply to: "time to move forward after the report of the AAD Task Force for the ABCDEs of Melanoma". J Am Acad Dermatol. 2015 Oct; 73(4):e151. PMID: 26369859.
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Gupta S, Artomov M, Goggins W, Daly M, Tsao H. Gender Disparity and Mutation Burden in Metastatic Melanoma. J Natl Cancer Inst. 2015 Nov; 107(11). PMID: 26296643; PMCID: PMC4643631 [Available on 11/01/16].
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Ho AW, Tsao H. Targeted Therapies in Melanoma: Translational Research at Its Finest. J Invest Dermatol. 2015 Aug; 135(8):1929-1933. PMID: 26174532; PMCID: PMC4505740.
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Tsao H, Begolka WS. Reply to: "The ABCDs of melanoma-A complicated morphologic message not intended for the general public". J Am Acad Dermatol. 2015 Aug; 73(2):e61. PMID: 26183999.
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Cirenajwis H, Ekedahl H, Lauss M, Harbst K, Carneiro A, Enoksson J, Rosengren F, Werner-Hartman L, Törngren T, Kvist A, Fredlund E, Bendahl PO, Jirström K, Lundgren L, Howlin J, Borg Å, Gruvberger-Saal SK, Saal LH, Nielsen K, Ringnér M, Tsao H, Olsson H, Ingvar C, Staaf J, Jönsson G. Molecular stratification of metastatic melanoma using gene expression profiling: Prediction of survival outcome and benefit from molecular targeted therapy. Oncotarget. 2015 May 20; 6(14):12297-309. PMID: 25909218; PMCID: PMC4494939.
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Luo S, Lobo AZ, Tanabe KK, Muzikansky A, Durazzo T, Sober A, Tsao H, Cosimi AB, Lawrence DP, Duncan LM. Clinical significance of microscopic melanoma metastases in the nonhottest sentinel lymph nodes. JAMA Surg. 2015 May; 150(5):465-72. PMID: 25831227.
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Ji Z, Erin Chen Y, Kumar R, Taylor M, Jenny Njauw CN, Miao B, Frederick DT, Wargo JA, Flaherty KT, Jönsson G, Tsao H. MITF Modulates Therapeutic Resistance through EGFR Signaling. J Invest Dermatol. 2015 Jul; 135(7):1863-1872. PMID: 25789707; PMCID: PMC4466007.
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Tsao H, Olazagasti JM, Cordoro KM, Brewer JD, Taylor SC, Bordeaux JS, Chren MM, Sober AJ, Tegeler C, Bhushan R, Begolka WS. Early detection of melanoma: reviewing the ABCDEs. J Am Acad Dermatol. 2015 Apr; 72(4):717-23. PMID: 25698455.
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Roh MR, Eliades P, Gupta S, Tsao H. Cutaneous Melanoma in Women. Int J Womens Dermatol. 2015 Feb 01; 1(1):21-25. PMID: 25844396.
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Paraiso KH, Das Thakur M, Fang B, Koomen JM, Fedorenko IV, John JK, Tsao H, Flaherty KT, Sondak VK, Messina JL, Pasquale EB, Villagra A, Rao UN, Kirkwood JM, Meier F, Sloot S, Gibney GT, Stuart D, Tawbi H, Smalley KS. Ligand-independent EPHA2 signaling drives the adoption of a targeted therapy-mediated metastatic melanoma phenotype. Cancer Discov. 2015 Mar; 5(3):264-73. PMID: 25542447; PMCID: PMC4355213.
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Miao B, Ji Z, Tan L, Taylor M, Zhang J, Choi HG, Frederick DT, Kumar R, Wargo JA, Flaherty KT, Gray NS, Tsao H. EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma. Cancer Discov. 2015 Mar; 5(3):274-87. PMID: 25542448; PMCID: PMC4355085.
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Kumar R, Taylor M, Miao B, Ji Z, Njauw JC, Jönsson G, Frederick DT, Tsao H. BAP1 has a survival role in cutaneous melanoma. J Invest Dermatol. 2015 Apr; 135(4):1089-1097. PMID: 25521456; PMCID: PMC4366338.
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Lin WM, Luo S, Muzikansky A, Lobo AZ, Tanabe KK, Sober AJ, Cosimi AB, Tsao H, Duncan LM. Outcome of patients with de novo versus nevus-associated melanoma. J Am Acad Dermatol. 2015 Jan; 72(1):54-8. PMID: 25440436.
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Luo S, Tsao H. Epidermal, sebaceous, and melanocytic nevoid proliferations are spectrums of mosaic RASopathies. J Invest Dermatol. 2014 Oct; 134(10):2493-2496. PMID: 25219651.
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Strazzula L, Vedak P, Hoang MP, Sober A, Tsao H, Kroshinsky D. The utility of re-excising mildly and moderately dysplastic nevi: a retrospective analysis. J Am Acad Dermatol. 2014 Dec; 71(6):1071-6. PMID: 25262175.
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Hawryluk EB, Tsao H. Melanoma: clinical features and genomic insights. Cold Spring Harb Perspect Med. 2014 Sep 02; 4(9):a015388. PMID: 25183853; PMCID: PMC4143108.
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Miller DM, Flaherty KT, Tsao H. Current status and future directions of molecularly targeted therapies and immunotherapies for melanoma. Semin Cutan Med Surg. 2014 Jun; 33(2):60-7. PMID: 25085663.
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Yonekawa Y, Kim IK, Gragoudas ES, Njauw CN, Tsao H, Jakobiec FA, Stacy RC. Aggressive skull base metastasis from uveal melanoma: a clinicopathologic study. Eur J Ophthalmol. 2014 Sep-Oct; 24(5):811-3. PMID: 24729140.
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Miller DM, Flaherty KT, Tsao H. Commentary: Molecular testing in melanoma. J Am Acad Dermatol. 2014 May; 70(5):863-70. PMID: 24534656.
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Marzuka-Alcalá A, Gabree MJ, Tsao H. Melanoma susceptibility genes and risk assessment. Methods Mol Biol. 2014; 1102:381-93. PMID: 24258989.
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Redmond RW, Rajadurai A, Udayakumar D, Sviderskaya EV, Tsao H. Melanocytes are selectively vulnerable to UVA-mediated bystander oxidative signaling. J Invest Dermatol. 2014 Apr; 134(4):1083-1090. PMID: 24335898; PMCID: PMC3961534.
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Ji Z, Kumar R, Taylor M, Rajadurai A, Marzuka-Alcalá A, Chen YE, Njauw CN, Flaherty K, Jönsson G, Tsao H. Vemurafenib synergizes with nutlin-3 to deplete survivin and suppresses melanoma viability and tumor growth. Clin Cancer Res. 2013 Aug 15; 19(16):4383-91. PMID: 23812671; PMCID: PMC3777641.
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Salas Fragomeni RA, Chung HW, Landesman Y, Senapedis W, Saint-Martin JR, Tsao H, Flaherty KT, Shacham S, Kauffman M, Cusack JC. CRM1 and BRAF inhibition synergize and induce tumor regression in BRAF-mutant melanoma. Mol Cancer Ther. 2013 Jul; 12(7):1171-9. PMID: 23615632.
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Chen YE, Tsao H. The skin microbiome: current perspectives and future challenges. J Am Acad Dermatol. 2013 Jul; 69(1):143-55. PMID: 23489584; PMCID: PMC3686918.
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Bis S, Tsao H. Melanoma genetics: the other side. Clin Dermatol. 2013 Mar-Apr; 31(2):148-55. PMID: 23438378.
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Chen ST, Geller AC, Tsao H. Update on the Epidemiology of Melanoma. Curr Dermatol Rep. 2013 Mar 01; 2(1):24-34. PMID: 23580930.
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Puntervoll HE, Yang XR, Vetti HH, Bachmann IM, Avril MF, Benfodda M, Catricalà C, Dalle S, Duval-Modeste AB, Ghiorzo P, Grammatico P, Harland M, Hayward NK, Hu HH, Jouary T, Martin-Denavit T, Ozola A, Palmer JM, Pastorino L, Pjanova D, Soufir N, Steine SJ, Stratigos AJ, Thomas L, Tinat J, Tsao H, Veinalde R, Tucker MA, Bressac-de Paillerets B, Newton-Bishop JA, Goldstein AM, Akslen LA, Molven A. Melanoma prone families with CDK4 germline mutation: phenotypic profile and associations with MC1R variants. J Med Genet. 2013 Apr; 50(4):264-70. PMID: 23384855; PMCID: PMC3607098.
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Lobo AZ, Tanabe KK, Luo S, Muzikansky A, Sober AJ, Tsao H, Cosimi AB, Duncan LM. The distribution of microscopic melanoma metastases in sentinel lymph nodes: implications for pathology protocols. Am J Surg Pathol. 2012 Dec; 36(12):1841-8. PMID: 23154770.
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Nikolaou V, Stratigos AJ, Tsao H. Hereditary nonmelanoma skin cancer. Semin Cutan Med Surg. 2012 Dec; 31(4):204-10. PMID: 23174490; PMCID: PMC3759014.
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Hung T, Piris A, Lobo A, Mihm MC, Sober AJ, Tsao H, Tanabe KK, Duncan LM. Sentinel lymph node metastasis is not predictive of poor outcome in patients with problematic spitzoid melanocytic tumors. Hum Pathol. 2013 Jan; 44(1):87-94. PMID: 22939951.
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Harbst K, Staaf J, Lauss M, Karlsson A, Måsbäck A, Johansson I, Bendahl PO, Vallon-Christersson J, Törngren T, Ekedahl H, Geisler J, Höglund M, Höglund M, Ringnér M, Ringnér M, Lundgren L, Jirström K, Olsson H, Ingvar C, Borg Å, Tsao H, Jönsson G. Molecular profiling reveals low- and high-grade forms of primary melanoma. Clin Cancer Res. 2012 Aug 01; 18(15):4026-36. PMID: 22675174; PMCID: PMC3467105.
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Tsao H, Chin L, Garraway LA, Fisher DE. Melanoma: from mutations to medicine. Genes Dev. 2012 Jun 01; 26(11):1131-55. PMID: 22661227; PMCID: PMC3371404.
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Njauw CN, Kim I, Piris A, Gabree M, Taylor M, Lane AM, DeAngelis MM, Gragoudas E, Duncan LM, Tsao H. Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families. PLoS One. 2012; 7(4):e35295. PMID: 22545102; PMCID: PMC3335872.
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Hawryluk EB, Sober AJ, Piris A, Nazarian RM, Hoang MP, Tsao H, Mihm MC, Duncan LM. Histologically challenging melanocytic tumors referred to a tertiary care pigmented lesion clinic. J Am Acad Dermatol. 2012 Oct; 67(4):727-35. PMID: 22521204.
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Nardi V, Song Y, Santamaria-Barria JA, Cosper AK, Lam Q, Faber AC, Boland GM, Yeap BY, Bergethon K, Scialabba VL, Tsao H, Settleman J, Ryan DP, Borger DR, Bhan AK, Hoang MP, Iafrate AJ, Cusack JC, Engelman JA, Dias-Santagata D. Activation of PI3K signaling in Merkel cell carcinoma. Clin Cancer Res. 2012 Mar 01; 18(5):1227-36. PMID: 22261808; PMCID: PMC3912509.
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Nikolaou VA, Stratigos AJ, Flaherty KT, Tsao H. Melanoma: new insights and new therapies. J Invest Dermatol. 2012 Mar; 132(3 Pt 2):854-63. PMID: 22217739; PMCID: PMC3759013.
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Luo S, Sepehr A, Tsao H. Spitz nevi and other Spitzoid lesions part II. Natural history and management. J Am Acad Dermatol. 2011 Dec; 65(6):1087-92. PMID: 22082839; PMCID: PMC3217195.
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Luo S, Sepehr A, Tsao H. Spitz nevi and other Spitzoid lesions part I. Background and diagnoses. J Am Acad Dermatol. 2011 Dec; 65(6):1073-84. PMID: 22082838; PMCID: PMC3217183.
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Yokoyama S, Woods SL, Boyle GM, Aoude LG, MacGregor S, Zismann V, Gartside M, Cust AE, Haq R, Harland M, Taylor JC, Duffy DL, Holohan K, Dutton-Regester K, Palmer JM, Bonazzi V, Stark MS, Symmons J, Law MH, Schmidt C, Lanagan C, O'Connor L, Holland EA, Schmid H, Maskiell JA, Jetann J, Ferguson M, Jenkins MA, Kefford RF, Giles GG, Armstrong BK, Aitken JF, Hopper JL, Whiteman DC, Pharoah PD, Easton DF, Dunning AM, Newton-Bishop JA, Montgomery GW, Martin NG, Mann GJ, Bishop DT, Tsao H, Trent JM, Fisher DE, Hayward NK, Brown KM. A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature. 2011 Nov 13; 480(7375):99-103. PMID: 22080950; PMCID: PMC3266855.
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Enzler T, Sano Y, Choo MK, Cottam HB, Karin M, Tsao H, Park JM. Cell-selective inhibition of NF-?B signaling improves therapeutic index in a melanoma chemotherapy model. Cancer Discov. 2011 Nov; 1(6):496-507. PMID: 22389871; PMCID: PMC3290412.
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Ji Z, Njauw CN, Taylor M, Neel V, Flaherty KT, Tsao H. p53 rescue through HDM2 antagonism suppresses melanoma growth and potentiates MEK inhibition. J Invest Dermatol. 2012 Feb; 132(2):356-64. PMID: 21993556.
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Ji Z, Flaherty KT, Tsao H. Targeting the RAS pathway in melanoma. Trends Mol Med. 2012 Jan; 18(1):27-35. PMID: 21962474; PMCID: PMC3759017.
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Bichakjian CK, Halpern AC, Johnson TM, Foote Hood A, Grichnik JM, Swetter SM, Tsao H, Barbosa VH, Chuang TY, Duvic M, Ho VC, Sober AJ, Beutner KR, Bhushan R, Smith Begolka W. Guidelines of care for the management of primary cutaneous melanoma. American Academy of Dermatology. J Am Acad Dermatol. 2011 Nov; 65(5):1032-47. PMID: 21868127.
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Chatzinasiou F, Lill CM, Kypreou K, Stefanaki I, Nicolaou V, Spyrou G, Evangelou E, Roehr JT, Kodela E, Katsambas A, Tsao H, Ioannidis JP, Bertram L, Stratigos AJ. Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma. J Natl Cancer Inst. 2011 Aug 17; 103(16):1227-35. PMID: 21693730; PMCID: PMC4719704.
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Sepehr A, Chao E, Trefrey B, Blackford A, Duncan LM, Flotte TJ, Sober A, Mihm MC, Tsao H. Long-term outcome of Spitz-type melanocytic tumors. Arch Dermatol. 2011 Oct; 147(10):1173-9. PMID: 21680758; PMCID: PMC3771496.
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Lipworth AD, Park JM, Trefrey BL, Rubin KM, Geller AC, Sober AJ, Tsao H. Urgent access to a specialty care melanoma clinic is associated with a higher rate of melanoma detection. J Am Acad Dermatol. 2011 Jun; 64(6):1060-7. PMID: 21453985.
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Luo S, Chaplin AC, Langley RG, Njauw CN, Duncan LM, Miller RA, Tsao H. Agminated segmental nevi demonstrating intranevic concordance of BRAF status. J Invest Dermatol. 2011 Mar; 131(3):788-90. PMID: 21160499; PMCID: PMC3173815.
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Ko JM, Velez NF, Tsao H. Pathways to melanoma. Semin Cutan Med Surg. 2010 Dec; 29(4):210-7. PMID: 21277534.
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Lang JM, Shennan M, Njauw JC, Luo S, Bishop JN, Harland M, Hayward NK, Tucker MA, Goldstein AM, Landi MT, Puig S, Gruis NA, Bergman W, Bianchi-Scarra G, Ghiorzo P, Hogg D, Tsao H. A flexible multiplex bead-based assay for detecting germline CDKN2A and CDK4 variants in melanoma-prone kindreds. J Invest Dermatol. 2011 Feb; 131(2):480-6. PMID: 21085193; PMCID: PMC3045700.
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Tsao H, Tanabe KK, Lawrence DP, Piris A. Case records of the Massachusetts General Hospital. Case 30-2010. A 15-year-old boy with a recurrent skin lesion. N Engl J Med. 2010 Sep 30; 363(14):1352-60. PMID: 20879885.
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Udayakumar D, Mahato B, Gabree M, Tsao H. Genetic determinants of cutaneous melanoma predisposition. Semin Cutan Med Surg. 2010 Sep; 29(3):190-5. PMID: 21051013; PMCID: PMC3759016.
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Boni A, Cogdill AP, Dang P, Udayakumar D, Njauw CN, Sloss CM, Ferrone CR, Flaherty KT, Lawrence DP, Fisher DE, Tsao H, Wargo JA. Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function. Cancer Res. 2010 Jul 01; 70(13):5213-9. PMID: 20551059.
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Feramisco JD, Tsao H, Siegel DH. Genetics for the practicing dermatologist. Semin Cutan Med Surg. 2010 Jun; 29(2):127-36. PMID: 20579602.
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Sober AJ, Tsao H. Martin C. Mihm, Jr and the history of the Pigmented Lesion Clinic at the Massachusetts General Hospital. J Cutan Pathol. 2010 Apr; 37 Suppl 1:8-11. PMID: 20482670.
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Ji Z, Flaherty KT, Tsao H. Molecular therapeutic approaches to melanoma. Mol Aspects Med. 2010 Apr; 31(2):194-204. PMID: 20176049.
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Wang W, Niendorf KB, Patel D, Blackford A, Marroni F, Sober AJ, Parmigiani G, Tsao H. Estimating CDKN2A carrier probability and personalizing cancer risk assessments in hereditary melanoma using MelaPRO. Cancer Res. 2010 Jan 15; 70(2):552-9. PMID: 20068151; PMCID: PMC2947347.
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Yang G, Thieu K, Tsai KY, Piris A, Udayakumar D, Njauw CN, Ramoni MF, Tsao H. Dynamic gene expression analysis links melanocyte growth arrest with nevogenesis. Cancer Res. 2009 Dec 01; 69(23):9029-37. PMID: 19903842.
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Udayakumar D, Tsao H. Moderate- to low-risk variant alleles of cutaneous malignancies and nevi: lessons from genome-wide association studies. Genome Med. 2009 Oct 27; 1(10):95. PMID: 19863770; PMCID: PMC2784308.
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Leachman SA, Carucci J, Kohlmann W, Banks KC, Asgari MM, Bergman W, Bianchi-Scarrà G, Brentnall T, Bressac-de Paillerets B, Bruno W, Curiel-Lewandrowski C, de Snoo FA, Debniak T, Demierre MF, Elder D, Goldstein AM, Grant-Kels J, Halpern AC, Ingvar C, Kefford RF, Lang J, MacKie RM, Mann GJ, Mueller K, Newton-Bishop J, Olsson H, Petersen GM, Puig S, Rigel D, Swetter SM, Tucker MA, Yakobson E, Zitelli JA, Tsao H. Selection criteria for genetic assessment of patients with familial melanoma. J Am Acad Dermatol. 2009 Oct; 61(4):677.e1-14. PMID: 19751883; PMCID: PMC3307795.
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Sadreyev RI, Feramisco JD, Tsao H, Grishin NV. Phenotypic categorization of genetic skin diseases reveals new relations between phenotypes, genes and pathways. Bioinformatics. 2009 Nov 15; 25(22):2891-6. PMID: 19744994; PMCID: PMC2773259.
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Park JM, Tsao H, Tsao S. Acquired bilateral nevus of Ota-like macules (Hori nevus): etiologic and therapeutic considerations. J Am Acad Dermatol. 2009 Jul; 61(1):88-93. PMID: 19539841.
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Feramisco JD, Sadreyev RI, Murray ML, Grishin NV, Tsao H. Phenotypic and genotypic analyses of genetic skin disease through the Online Mendelian Inheritance in Man (OMIM) database. J Invest Dermatol. 2009 Nov; 129(11):2628-36. PMID: 19536140.
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Udayakumar D, Tsao H. Melanoma genetics: an update on risk-associated genes. Hematol Oncol Clin North Am. 2009 Jun; 23(3):415-29, vii. PMID: 19464594.
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Nelson AA, Tsao H. Melanoma and genetics. Clin Dermatol. 2009 Jan-Feb; 27(1):46-52. PMID: 19095153.
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Sun BK, Tsao H. Small RNAs in development and disease. J Am Acad Dermatol. 2008 Nov; 59(5):725-37; quiz 738-40. PMID: 19119093.
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Hocker TL, Singh MK, Tsao H. Melanoma genetics and therapeutic approaches in the 21st century: moving from the benchside to the bedside. J Invest Dermatol. 2008 Nov; 128(11):2575-95. PMID: 18927540.
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Lin J, Hocker TL, Singh M, Tsao H. Genetics of melanoma predisposition. Br J Dermatol. 2008 Aug; 159(2):286-91. PMID: 18547303.
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Sun BK, Tsao H. X-chromosome inactivation and skin disease. J Invest Dermatol. 2008 Dec; 128(12):2753-9. PMID: 18509358.
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Harland M, Goldstein AM, Kukalizch K, Taylor C, Hogg D, Puig S, Badenas C, Gruis N, ter Huurne J, Bergman W, Hayward NK, Stark M, Tsao H, Tucker MA, Landi MT, Scarra GB, Ghiorzo P, Kanetsky PA, Elder D, Mann GJ, Holland EA, Bishop DT, Bishop JN. A comparison of CDKN2A mutation detection within the Melanoma Genetics Consortium (GenoMEL). Eur J Cancer. 2008 Jun; 44(9):1269-74. PMID: 18394881; PMCID: PMC2494985.
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Friedman RJ, Gutkowicz-Krusin D, Farber MJ, Warycha M, Schneider-Kels L, Papastathis N, Mihm MC, Googe P, King R, Prieto VG, Kopf AW, Polsky D, Rabinovitz H, Oliviero M, Cognetta A, Rigel DS, Marghoob A, Rivers J, Johr R, Grant-Kels JM, Tsao H. The diagnostic performance of expert dermoscopists vs a computer-vision system on small-diameter melanomas. Arch Dermatol. 2008 Apr; 144(4):476-82. PMID: 18427041.
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Zhang G, Njauw CN, Park JM, Naruse C, Asano M, Tsao H. EphA2 is an essential mediator of UV radiation-induced apoptosis. Cancer Res. 2008 Mar 15; 68(6):1691-6. PMID: 18339848; PMCID: PMC4469360.
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Park JM, Tsao H, Tsao S. Combined use of intense pulsed light and Q-switched ruby laser for complex dyspigmentation among Asian patients. Lasers Surg Med. 2008 Feb; 40(2):128-33. PMID: 18306166.
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Feramisco JD, Cayce RL, Casey RL, Tsao H. Recent updates on genetics: teaching old dogmas new tricks. Pediatr Dermatol. 2008 Jan-Feb; 25(1):99-108. PMID: 18304166.
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Somoano B, Tsao H. Genodermatoses with cutaneous tumors and internal malignancies. Dermatol Clin. 2008 Jan; 26(1):69-87, viii. PMID: 18023772.
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McDermott U, Sharma SV, Dowell L, Greninger P, Montagut C, Lamb J, Archibald H, Raudales R, Tam A, Lee D, Rothenberg SM, Supko JG, Sordella R, Ulkus LE, Iafrate AJ, Maheswaran S, Njauw CN, Tsao H, Drew L, Hanke JH, Ma XJ, Erlander MG, Gray NS, Haber DA, Settleman J. Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. Proc Natl Acad Sci U S A. 2007 Dec 11; 104(50):19936-41. PMID: 18077425; PMCID: PMC2148401.
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Jarell AD, Lawrence D, Tsao H. The RAS/mitogen activated protein (MAP) kinase pathway in melanoma biology and therapeutics. Biologics. 2007 Dec; 1(4):407-14. PMID: 19707310; PMCID: PMC2721285.
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Singh M, Lin J, Hocker TL, Tsao H. Genetics of melanoma tumorigenesis. Br J Dermatol. 2008 Jan; 158(1):15-21. PMID: 18047516.
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Tsao H, Florez JC. Introduction to genetic association studies. J Invest Dermatol. 2007 Oct; 127(10):2283-7. PMID: 17853910.
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Yang G, Curley D, Bosenberg MW, Tsao H. Loss of xeroderma pigmentosum C (Xpc) enhances melanoma photocarcinogenesis in Ink4a-Arf-deficient mice. Cancer Res. 2007 Jun 15; 67(12):5649-57. PMID: 17575131.
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Hocker T, Tsao H. Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants. Hum Mutat. 2007 Jun; 28(6):578-88. PMID: 17295241.
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Tsai KY, Tsao H. Primer on the human genome. J Am Acad Dermatol. 2007 May; 56(5):719-35. PMID: 17437886.
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Lang J, Hayward N, Goldgar D, Tsao H, Hogg D, Palmer J, Stark M, Tobias ES, MacKie R. The M53I mutation in CDKN2A is a founder mutation that predominates in melanoma patients with Scottish ancestry. Genes Chromosomes Cancer. 2007 Mar; 46(3):277-87. PMID: 17171691.
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Goldstein AM, Chan M, Harland M, Gillanders EM, Hayward NK, Avril MF, Azizi E, Bianchi-Scarra G, Bishop DT, Bressac-de Paillerets B, Bruno W, Calista D, Cannon Albright LA, Demenais F, Elder DE, Ghiorzo P, Gruis NA, Hansson J, Hogg D, Holland EA, Kanetsky PA, Kefford RF, Landi MT, Lang J, Leachman SA, Mackie RM, Magnusson V, Mann GJ, Niendorf K, Newton Bishop J, Palmer JM, Puig S, Puig-Butille JA, de Snoo FA, Stark M, Tsao H, Tucker MA, Whitaker L, Yakobson E. High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL. Cancer Res. 2006 Oct 15; 66(20):9818-28. PMID: 17047042.
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Goldstein AM, Chan M, Harland M, Hayward NK, Demenais F, Bishop DT, Azizi E, Bergman W, Bianchi-Scarra G, Bruno W, Calista D, Albright LA, Chaudru V, Chompret A, Cuellar F, Elder DE, Ghiorzo P, Gillanders EM, Gruis NA, Hansson J, Hogg D, Holland EA, Kanetsky PA, Kefford RF, Landi MT, Lang J, Leachman SA, MacKie RM, Magnusson V, Mann GJ, Bishop JN, Palmer JM, Puig S, Puig-Butille JA, Stark M, Tsao H, Tucker MA, Whitaker L, Yakobson E. Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents. J Med Genet. 2007 Feb; 44(2):99-106. PMID: 16905682; PMCID: PMC2598064.
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Yang G, Zhang G, Pittelkow MR, Ramoni M, Tsao H. Expression profiling of UVB response in melanocytes identifies a set of p53-target genes. J Invest Dermatol. 2006 Nov; 126(11):2490-506. PMID: 16888633.
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Haluska FG, Tsao H, Wu H, Haluska FS, Lazar A, Goel V. Genetic alterations in signaling pathways in melanoma. Clin Cancer Res. 2006 Apr 01; 12(7 Pt 2):2301s-2307s. PMID: 16609049.
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Stratigos AJ, Yang G, Dimisianos R, Nicolaou V, Stefanaki I, Katsambas AD, Tsao H. Germline CDKN2A mutations among Greek patients with early-onset and multiple primary cutaneous melanoma. J Invest Dermatol. 2006 Feb; 126(2):399-401. PMID: 16374456.
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Niendorf KB, Tsao H. Cutaneous melanoma: family screening and genetic testing. Dermatol Ther. 2006 Jan-Feb; 19(1):1-8. PMID: 16405564.
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Goggins W, Daniels GH, Tsao H. Elevation of thyroid cancer risk among cutaneous melanoma survivors. Int J Cancer. 2006 Jan 01; 118(1):185-8. PMID: 16049985.
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Tsao H. The SNPs of RAF. J Invest Dermatol. 2005 Dec; 125(6):xiv-xv. PMID: 16354174.
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Yang G, Rajadurai A, Tsao H. Recurrent patterns of dual RB and p53 pathway inactivation in melanoma. J Invest Dermatol. 2005 Dec; 125(6):1242-51. PMID: 16354195.
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Niendorf KB, Goggins W, Yang G, Tsai KY, Shennan M, Bell DW, Sober AJ, Hogg D, Tsao H. MELPREDICT: a logistic regression model to estimate CDKN2A carrier probability. J Med Genet. 2006 Jun; 43(6):501-6. PMID: 16169933; PMCID: PMC2564534.
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Tsao H, Sober AJ. Melanoma treatment update. Dermatol Clin. 2005 Apr; 23(2):323-33. PMID: 15837158.
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Somoano B, Niendorf KB, Tsao H. Hereditary cancer syndromes of the skin. Clin Dermatol. 2005 Jan-Feb; 23(1):85-106. PMID: 15708293.
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Tsai KY, Tsao H. The genetics of skin cancer. Am J Med Genet C Semin Med Genet. 2004 Nov 15; 131C(1):82-92. PMID: 15468170.
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Tsao H, Niendorf K. Genetic testing in hereditary melanoma. J Am Acad Dermatol. 2004 Nov; 51(5):803-8. PMID: 15523363.
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Goggins W, Gao W, Tsao H. Association between female breast cancer and cutaneous melanoma. Int J Cancer. 2004 Sep 20; 111(5):792-4. PMID: 15252852.
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Tsao H, Atkins MB, Sober AJ. Management of cutaneous melanoma. N Engl J Med. 2004 Sep 02; 351(10):998-1012. PMID: 15342808.
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Yang G, Niendorf KB, Tsao H. A novel methionine-53-valine mutation of p16 in a hereditary melanoma kindred. J Invest Dermatol. 2004 Sep; 123(3):574-5. PMID: 15304098.
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Tsao H, Sober AJ, Niendorf KB, Zembowicz A. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 7-2004. A 48-year-old woman with multiple pigmented lesions and a personal and family history of melanoma. N Engl J Med. 2004 Feb 26; 350(9):924-32. PMID: 14985491.
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Tsao H, Goel V, Wu H, Yang G, Haluska FG. Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma. J Invest Dermatol. 2004 Feb; 122(2):337-41. PMID: 15009714; PMCID: PMC2586668.
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Tsao H, Feldman M, Fullerton JE, Sober AJ, Rosenthal D, Goggins W. Early detection of asymptomatic pulmonary melanoma metastases by routine chest radiographs is not associated with improved survival. Arch Dermatol. 2004 Jan; 140(1):67-70. PMID: 14732662.
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Bevona C, Goggins W, Quinn T, Fullerton J, Tsao H. Cutaneous melanomas associated with nevi. Arch Dermatol. 2003 Dec; 139(12):1620-4; discussion 1624. PMID: 14676081.
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Tsao H, Mihm MC, Sheehan C. PTEN expression in normal skin, acquired melanocytic nevi, and cutaneous melanoma. J Am Acad Dermatol. 2003 Nov; 49(5):865-72. PMID: 14576666.
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Bevona C, Tannous Z, Tsao H. Dermal melanocytic proliferation with features of a plaque-type blue nevus and neurocristic hamartoma. J Am Acad Dermatol. 2003 Nov; 49(5):924-9. PMID: 14576682.
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Tsao H, Bevona C, Goggins W, Quinn T. The transformation rate of moles (melanocytic nevi) into cutaneous melanoma: a population-based estimate. Arch Dermatol. 2003 Mar; 139(3):282-8. PMID: 12622618.
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Goggins WB, Tsao H. A population-based analysis of risk factors for a second primary cutaneous melanoma among melanoma survivors. Cancer. 2003 Feb 01; 97(3):639-43. PMID: 12548605.
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Rheinwald JG, Hahn WC, Ramsey MR, Wu JY, Guo Z, Tsao H, De Luca M, Catricalà C, O'Toole KM. A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status. Mol Cell Biol. 2002 Jul; 22(14):5157-72. PMID: 12077343; PMCID: PMC139780.
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Tsao H, Millman P, Linette GP, Hodi FS, Sober AJ, Goldberg MA, Haluska FG. Hypopigmentation associated with an adenovirus-mediated gp100/MART-1-transduced dendritic cell vaccine for metastatic melanoma. Arch Dermatol. 2002 Jun; 138(6):799-802. PMID: 12056962.
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Tsao H, Kwitkiwski K, Sober AJ. A single-institution case series of patients with cutaneous melanoma and non-Hodgkin's lymphoma. J Am Acad Dermatol. 2002 Jan; 46(1):55-61. PMID: 11756946.
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Tsao H. Genetics of nonmelanoma skin cancer. Arch Dermatol. 2001 Nov; 137(11):1486-92. PMID: 11708952.
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Tsao H, Nadiminti U, Sober AJ, Bigby M. A meta-analysis of reverse transcriptase-polymerase chain reaction for tyrosinase mRNA as a marker for circulating tumor cells in cutaneous melanoma. Arch Dermatol. 2001 Mar; 137(3):325-30. PMID: 11255333.
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Goggins WB, Finkelstein DM, Tsao H. Evidence for an association between cutaneous melanoma and non-Hodgkin lymphoma. Cancer. 2001 Feb 15; 91(4):874-80. PMID: 11241258.
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Tsao H, Zhang X, Kwitkiwski K, Finkelstein DM, Sober AJ, Haluska FG. Low prevalence of germline CDKN2A and CDK4 mutations in patients with early-onset melanoma. Arch Dermatol. 2000 Sep; 136(9):1118-22. PMID: 10987867.
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Tsao H, Lerner LH. Pigmented purpuric eruption associated with injection medroxyprogesterone acetate. J Am Acad Dermatol. 2000 Aug; 43(2 Pt 1):308-10. PMID: 10906656.
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Tsao H. Update on familial cancer syndromes and the skin. J Am Acad Dermatol. 2000 Jun; 42(6):939-69; quiz 970-2. PMID: 10827397.
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Jonasch E, Kumar UN, Linette GP, Hodi FS, Soiffer RJ, Ryan BF, Sober AJ, Mihm MC, Tsao H, Langley RG, Cosimi BA, Gadd MA, Tanabe KK, Souba W, Haynes HA, Barnhill R, Osteen R, Haluska FG. Adjuvant high-dose interferon alfa-2b in patients with high-risk melanoma. Cancer J. 2000 May-Jun; 6(3):139-45. PMID: 10882328.
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Tsao H, Zhang X, Fowlkes K, Haluska FG. Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous melanoma cell lines. Cancer Res. 2000 Apr 01; 60(7):1800-4. PMID: 10766161.
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Tsao H. American Academy of Dermatology 1999 Awards for Young Investigators in Dermatology. Targets of genetic injury in cutaneous melanoma. J Am Acad Dermatol. 1999 Sep; 41(3 Pt 1):459-61. PMID: 10507912.
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Tsao H, Tahan SR. Images in clinical medicine. Keratoacanthoma. N Engl J Med. 1999 Mar 04; 340(9):708. PMID: 10053180.
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Zhang X, Tsao H, Tsuji T, Minoshima S, McBride J, Majewski P, Todd R, Shimizu N, Wong DT, Housman DE, Haluska FG. Identification and mutation analysis of DOC-1R, a DOC-1 growth suppressor-related gene. Biochem Biophys Res Commun. 1999 Feb 05; 255(1):59-63. PMID: 10082655.
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Tsao H, Zhang X, Majewski P, Haluska FG. Mutational and expression analysis of the p73 gene in melanoma cell lines. Cancer Res. 1999 Jan 01; 59(1):172-4. PMID: 9892203.
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Tsao H, Sober AJ. Multiple lipomatosis in a patient with familial atypical mole syndrome. Br J Dermatol. 1998 Dec; 139(6):1118-9. PMID: 9990390.
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Tsao H, Zhang X, Benoit E, Haluska FG. Identification of PTEN/MMAC1 alterations in uncultured melanomas and melanoma cell lines. Oncogene. 1998 Jul 02; 16(26):3397-402. PMID: 9692547.
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Tsao H, Rogers GS, Sober AJ. An estimate of the annual direct cost of treating cutaneous melanoma. J Am Acad Dermatol. 1998 May; 38(5 Pt 1):669-80. PMID: 9591809.
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Lee PK, Rosenberg CN, Tsao H, Sober AJ. Failure of Q-switched ruby laser to eradicate atypical-appearing solar lentigo: report of two cases. J Am Acad Dermatol. 1998 Feb; 38(2 Pt 2):314-7. PMID: 9486705.
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Tsao H, Sober AJ. Ultraviolet radiation and malignant melanoma. Clin Dermatol. 1998 Jan-Feb; 16(1):67-73. PMID: 9472435.
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Tsao H, Benoit E, Sober AJ, Thiele C, Haluska FG. Novel mutations in the p16/CDKN2A binding region of the cyclin-dependent kinase-4 gene. Cancer Res. 1998 Jan 01; 58(1):109-13. PMID: 9426066.
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Haluska FG, Thiele C, Goldstein A, Tsao H, Benoit EP, Housman D. Lack of phospholipase A2 mutations in neuroblastoma, melanoma and colon-cancer cell lines. Int J Cancer. 1997 Jul 17; 72(2):337-9. PMID: 9219842.
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Tsao H, Cosimi AB, Sober AJ. Ultra-late recurrence (15 years or longer) of cutaneous melanoma. Cancer. 1997 Jun 15; 79(12):2361-70. PMID: 9191524.
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Tsao H, Sober AJ, Barnhill RL. Desmoplastic neurotropic melanoma. Semin Cutan Med Surg. 1997 Jun; 16(2):131-6. PMID: 9220552.
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Tsao H, Tahan SR, Johnson RA. Chronic varicella zoster infection mimicking a basal cell carcinoma in an AIDS patient. J Am Acad Dermatol. 1997 May; 36(5 Pt 2):831-3. PMID: 9146560.
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Luo SF, Chiu CT, Tsao HL, Fan LW, Tsai CT, Pan SL, Yang CM. Effect of forskolin on bradykinin-induced calcium mobilization in cultured canine tracheal smooth muscle cells. Cell Signal. 1997 Feb; 9(2):159-67. PMID: 9113415.
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Tsao H, Busam K, Barnhill RL, Haynes HA. Lesions resembling malignant atrophic papulosis in a patient with dermatomyositis. J Am Acad Dermatol. 1997 Feb; 36(2 Pt 2):317-9. PMID: 9039209.
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Tsao H, Busam K, Barnhill RL, Dover JS. Treatment of minocycline-induced hyperpigmentation with the Q-switched ruby laser. Arch Dermatol. 1996 Oct; 132(10):1250-1. PMID: 8859045.
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de la Zerda A, Chiu-Tsao ST, Lin J, Boulay LL, Kanna I, Kim JH, Tsao HS. 125I eye plaque dose distribution including penumbra characteristics. Med Phys. 1996 Mar; 23(3):407-18. PMID: 8815384.
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Luo SF, Tsao HL, Ong R, Hsieh JT, Yang CM. Inhibitory effect of phorbol ester on bradykinin-induced phosphoinositide hydrolysis and calcium mobilization in cultured canine tracheal smooth muscle cells. Cell Signal. 1995 Aug; 7(6):571-81. PMID: 8588973.
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Loeb DM, Tsao H, Cobb MH, Greene LA. NGF and other growth factors induce an association between ERK1 and the NGF receptor, gp140prototrk. Neuron. 1992 Dec; 9(6):1053-65. PMID: 1463607.
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Tsao H, Greene LA. The roles of macromolecular synthesis and phosphorylation in the regulation of a protein kinase activity transiently stimulated by nerve growth factor. J Biol Chem. 1991 Jul 15; 266(20):12981-8. PMID: 2071585.
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Tsao H, Aletta JM, Greene LA. Nerve growth factor and fibroblast growth factor selectively activate a protein kinase that phosphorylates high molecular weight microtubule-associated proteins. Detection, partial purification, and characterization in PC12 cells. J Biol Chem. 1990 Sep 15; 265(26):15471-80. PMID: 2394735.