Harvard Catalyst Profiles

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Hensin Tsao, M.D., Ph.D.

Title
Institution
Department
Address
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Other Positions
Title
Institution
Department

Mentoring
Predictors of Outcome for Patellar and Trochlear Osteochondritis Dissecans in a Pediatric Population
Summer, 06/13/11 - 08/01/11

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P01CA163222 (FISHER, DAVID E) Mar 12, 2013 - Jun 30, 2024
    NIH
    Targetable epigenetic and transcriptional mechanisms in melanoma that shape the microenvironment
    Role: Co-Principal Investigator
  2. K24CA149202 (TSAO, HENSIN) May 1, 2010 - Apr 30, 2020
    NIH
    Molecular Genetics of Melanoma
    Role: Principal Investigator
  3. R21ES013964 (TSAO, HENSIN) Jul 1, 2008 - Jun 30, 2010
    NIH
    The Role of EphA2 in UV-mediated Apoptosis
    Role: Principal Investigator
  4. K08CA095532 (TSAO, HENSIN) Aug 1, 2003 - Jul 31, 2008
    NIH
    Nucleotide Excision Repair in Cutaneous Melanoma
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Njauw CN, Ji Z, Pham DM, Simoneau A, Kumar R, Flaherty KT, Zou L, Tsao H. Oncogenic KIT Induces Replication Stress and Confers Cell Cycle Checkpoint Vulnerability in Melanoma. J Invest Dermatol. 2022 May; 142(5):1413-1424.e6. PMID: 34687746.
    Citations:    Fields:    Translation:Animals
  2. Rashid S, Klebanov N, Lin WM, Tsao H. Unsupervised Phenotype-Based Clustering of Clinicopathologic Features in Cutaneous Melanoma. JID Innov. 2021 Dec; 1(4):100047. PMID: 34909744.
    Citations:    
  3. Rashid S, Tsao H. Recognition, Staging, and Management of Melanoma. Med Clin North Am. 2021 Jul; 105(4):643-661. PMID: 34059243.
    Citations:    Fields:    Translation:Humans
  4. Rashid S, Tsao H. Effect of the COVID-19 Pandemic on Delayed Skin Cancer Services. Dermatol Clin. 2021 Oct; 39(4):627-637. PMID: 34556252.
    Citations: 2     Fields:    Translation:Humans
  5. Coroiu A, Moran C, Davine JA, Brophy K, Bergeron C, Tsao H, Körner A, Swetter SM, Geller AC. Patient-identified early clinical warning signs of nodular melanoma: a qualitative study. BMC Cancer. 2021 Apr 07; 21(1):371. PMID: 33827477.
    Citations:    Fields:    Translation:Humans
  6. Guhan SM, Shaughnessy M, Rajadurai A, Taylor M, Kumar R, Ji Z, Rashid S, Flaherty K, Tsao H. The Molecular Context of Vulnerability for CDK9 Suppression in Triple Wild-Type Melanoma. J Invest Dermatol. 2021 08; 141(8):2018-2027.e4. PMID: 33745909.
    Citations:    Fields:    Translation:HumansCells
  7. Atkins MB, Curiel-Lewandrowski C, Fisher DE, Swetter SM, Tsao H, Aguirre-Ghiso JA, Soengas MS, Weeraratna AT, Flaherty KT, Herlyn M, Sosman JA, Tawbi HA, Pavlick AC, Cassidy PB, Chandra S, Chapman PB, Daud A, Eroglu Z, Ferris LK, Fox BA, Gershenwald JE, Gibney GT, Grossman D, Hanks BA, Hanniford D, Hernando E, Jeter JM, Johnson DB, Khleif SN, Kirkwood JM, Leachman SA, Mays D, Nelson KC, Sondak VK, Sullivan RJ, Merlino G. The State of Melanoma: Emergent Challenges and Opportunities. Clin Cancer Res. 2021 05 15; 27(10):2678-2697. PMID: 33414132.
    Citations: 8     Fields:    Translation:HumansCells
  8. Ji Z, Njauw CN, Guhan S, Kumar R, Reddy B, Rajadurai A, Flaherty K, Tsao H. Loss of ACK1 Upregulates EGFR and Mediates Resistance to BRAF Inhibition. J Invest Dermatol. 2021 05; 141(5):1317-1324.e1. PMID: 33159968.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  9. Guhan SM, Artomov M, McCormick S, Njauw C-, Stratigos AJ, Shannon K, Ellisen LW, Tsao H. Cancer risks associated with the germline MITF(E318K) variant. Sci Rep. 2020 10 13; 10(1):17051. PMID: 33051548.
    Citations: 3     Fields:    Translation:HumansCells
  10. Chan WH, Tsao H. Consensus, Controversy, and Conversations About Gene Expression Profiling in Melanoma. JAMA Dermatol. 2020 09 01; 156(9):949-951. PMID: 32745178.
    Citations: 2     Fields:    Translation:Humans
  11. Guhan S, Boland G, Tanabe K, Lin W, Reddy B, Hawryluk EB, Sober AJ, Tsao H. Surgical delay and mortality for primary cutaneous melanoma. J Am Acad Dermatol. 2021 Apr; 84(4):1089-1091. PMID: 32711092.
    Citations: 1     Fields:    Translation:HumansCells
  12. Pham DDM, Guhan S, Tsao H. KIT and Melanoma: Biological Insights and Clinical Implications. Yonsei Med J. 2020 Jul; 61(7):562-571. PMID: 32608199.
    Citations: 16     Fields:    Translation:HumansCells
  13. Beaulieu D, Tsao H, Michaud DS, Okhovat JP, Halpern AC, Lundberg M, Geller AC. A geographically based cross-sectional analysis of SPOT me skin cancer screening data. J Am Acad Dermatol. 2021 Mar; 84(3):809-810.e3. PMID: 32534079.
    Citations:    Fields:    Translation:HumansPHPublic Health
  14. Kang Y, Roh MR, Rajadurai S, Rajadurai A, Kumar R, Njauw CN, Zheng Z, Tsao H. Hypoxia and HIF-1a Regulate Collagen Production in Keloids. J Invest Dermatol. 2020 11; 140(11):2157-2165. PMID: 32315657.
    Citations: 6     Fields:    Translation:HumansCells
  15. Nguyen ED, Xue YK, Danesh M, Ameri A, Weng CQ, Klebanov N, Foreman RK, Nazarian RM, Demehri S, Tsao H, Kroshinsky D. A Case of Nivolumab-Induced Cutaneous Toxicity with Multiple Morphologies. Dermatopathology (Basel). 2019 Oct-Dec; 6(4):255-259. PMID: 32232031.
    Citations: 1     
  16. Shaughnessy M, Lamuraglia G, Klebanov N, Ji Z, Rajadurai A, Kumar R, Flaherty K, Tsao H. Selective uveal melanoma inhibition with calcium channel blockade. Int J Oncol. 2019 Nov; 55(5):1090-1096. PMID: 31545410.
    Citations: 2     Fields:    Translation:HumansCells
  17. Shaughnessy M, Njauw CN, Artomov M, Tsao H. Classifying Melanoma by TERT Promoter Mutational Status. J Invest Dermatol. 2020 02; 140(2):390-394.e1. PMID: 31425705.
    Citations: 7     Fields:    Translation:HumansCells
  18. Zhang AJ, Rush PS, Tsao H, Duncan LM. BRCA1-associated protein (BAP1)-inactivated melanocytic tumors. J Cutan Pathol. 2019 Dec; 46(12):965-972. PMID: 31233225.
    Citations: 7     Fields:    Translation:HumansCells
  19. Beaulieu D, Tsao H, Michaud DS, Okhovat JP, Halpern AC, Geller AC. Number needed to screen for presumptive screening diagnoses among first-time SPOTme screening participants (1992-2010). J Am Acad Dermatol. 2020 01; 82(1):233-234. PMID: 31228527.
    Citations:    Fields:    Translation:Humans
  20. Phung B, Ciesla M, Sanna A, Guzzi N, Beneventi G, Cao Thi Ngoc P, Lauss M, Cabrita R, Cordero E, Bosch A, Rosengren F, Häkkinen J, Griewank K, Paschen A, Harbst K, Olsson H, Ingvar C, Carneiro A, Tsao H, Schadendorf D, Pietras K, Bellodi C, Jönsson G. The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma. Cell Rep. 2019 06 18; 27(12):3573-3586.e7. PMID: 31216476.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  21. Klebanov N, Artomov M, Goggins WB, Daly E, Daly MJ, Tsao H. Burden of unique and low prevalence somatic mutations correlates with cancer survival. Sci Rep. 2019 03 19; 9(1):4848. PMID: 30890735.
    Citations: 25     Fields:    Translation:Humans
  22. Artomov M, Joseph V, Tiao G, Thomas T, Schrader K, Klein RJ, Kiezun A, Gupta N, Margolin L, Stratigos AJ, Kim I, Shannon K, Ellisen LW, Haber D, Getz G, Tsao H, Lipkin SM, Altshuler D, Offit K, Daly MJ. Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes. Eur J Hum Genet. 2019 05; 27(5):824-828. PMID: 30718883.
    Citations: 2     Fields:    Translation:Humans
  23. Klebanov N, Lin WM, Artomov M, Shaughnessy M, Njauw CN, Bloom R, Eterovic AK, Chen K, Kim TB, Tsao SS, Tsao H. Use of Targeted Next-Generation Sequencing to Identify Activating Hot Spot Mutations in Cherry Angiomas. JAMA Dermatol. 2019 02 01; 155(2):211-215. PMID: 30601876.
    Citations: 5     Fields:    Translation:Humans
  24. Kumar R, Njauw CN, Reddy BY, Ji Z, Rajadurai A, Klebanov N, Tsao H. Growth suppression by dual BRAF(V600E) and NRAS(Q61) oncogene expression is mediated by SPRY4 in melanoma. Oncogene. 2019 05; 38(18):3504-3520. PMID: 30651601.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  25. Beaulieu D, Tsao H, Michaud DS, Okhovat JP, Halpern AC, Geller AC. Factors associated with suspected nonmelanoma skin cancers, dysplastic nevus, and cutaneous melanoma among first-time SPOTme screening program participants (2009-2010). J Am Acad Dermatol. 2018 Dec 10. PMID: 30543833.
    Citations:    Fields:    
  26. Walpole S, Pritchard AL, Cebulla CM, Pilarski R, Stautberg M, Davidorf FH, de la Fouchardière A, Cabaret O, Golmard L, Stoppa-Lyonnet D, Garfield E, Njauw CN, Cheung M, Turunen JA, Repo P, Järvinen RS, van Doorn R, Jager MJ, Luyten GPM, Marinkovic M, Chau C, Potrony M, Höiom V, Helgadottir H, Pastorino L, Bruno W, Andreotti V, Dalmasso B, Ciccarese G, Queirolo P, Mastracci L, Wadt K, Kiilgaard JF, Speicher MR, van Poppelen N, Kilic E, Al-Jamal RT, Dianzani I, Betti M, Bergmann C, Santagata S, Dahiya S, Taibjee S, Burke J, Poplawski N, O'Shea SJ, Newton-Bishop J, Adlard J, Adams DJ, Lane AM, Kim I, Klebe S, Racher H, Harbour JW, Nickerson ML, Murali R, Palmer JM, Howlie M, Symmons J, Hamilton H, Warrier S, Glasson W, Johansson P, Robles-Espinoza CD, Ossio R, de Klein A, Puig S, Ghiorzo P, Nielsen M, Kivelä TT, Tsao H, Testa JR, Gerami P, Stern MH, Paillerets BB, Abdel-Rahman MH, Hayward NK. Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide. J Natl Cancer Inst. 2018 12 01; 110(12):1328-1341. PMID: 30517737.
    Citations: 53     Fields:    Translation:Humans
  27. Swetter SM, Tsao H, Bichakjian CK, Curiel-Lewandrowski C, Elder DE, Gershenwald JE, Guild V, Grant-Kels JM, Halpern AC, Johnson TM, Sober AJ, Thompson JA, Wisco OJ, Wyatt S, Hu S, Lamina T. Guidelines of care for the management of primary cutaneous melanoma. J Am Acad Dermatol. 2019 01; 80(1):208-250. PMID: 30392755.
    Citations: 73     Fields:    Translation:Humans
  28. Karagianni F, Njauw CN, Kypreou KP, Stergiopoulou A, Plaka M, Polydorou D, Chasapi V, Pappas L, Stratigos IA, Champsas G, Panagiotou P, Gogas H, Evangelou E, Tsao H, Stratigos AJ, Stefanaki I. CDKN2A/CDK4 Status in Greek Patients with Familial Melanoma and Association with Clinico-epidemiological Parameters. Acta Derm Venereol. 2018 Oct 10; 98(9):862-866. PMID: 29774366.
    Citations: 4     Fields:    Translation:Humans
  29. Klebanov N, Gunasekera NS, Lin WM, Hawryluk EB, Miller DM, Reddy BY, Christman MP, Beaulieu D, Rajadurai S, Duncan LM, Sober AJ, Tsao H. Clinical spectrum of cutaneous melanoma morphology. J Am Acad Dermatol. 2019 Jan; 80(1):178-188.e3. PMID: 30165162.
    Citations: 3     Fields:    Translation:Humans
  30. Okhovat JP, Beaulieu D, Tsao H, Halpern AC, Michaud DS, Shaykevich S, Geller AC. The first 30 years of the American Academy of Dermatology skin cancer screening program: 1985-2014. J Am Acad Dermatol. 2018 Nov; 79(5):884-891.e3. PMID: 30057360.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  31. Klebanov N, Reddy BY, Husain S, Silvers DN, Grossman ME, Tsao H. Cutaneous Presentation of Mesothelioma With a Sarcomatoid Transformation. Am J Dermatopathol. 2018 May; 40(5):378-382. PMID: 29059099.
    Citations: 1     Fields:    Translation:Humans
  32. Bartenstein DW, Kelleher CM, Friedmann AM, Duncan LM, Tsao H, Sober AJ, Hawryluk EB. Contrasting features of childhood and adolescent melanomas. Pediatr Dermatol. 2018 May; 35(3):354-360. PMID: 29569376.
    Citations: 6     Fields:    Translation:Humans
  33. Eliades P, Abraham BJ, Ji Z, Miller DM, Christensen CL, Kwiatkowski N, Kumar R, Njauw CN, Taylor M, Miao B, Zhang T, Wong KK, Gray NS, Young RA, Tsao H. High MITF Expression Is Associated with Super-Enhancers and Suppressed by CDK7 Inhibition in Melanoma. J Invest Dermatol. 2018 07; 138(7):1582-1590. PMID: 29408204.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  34. Artomov M, Stratigos AJ, Kim I, Kumar R, Lauss M, Reddy BY, Miao B, Daniela Robles-Espinoza C, Sankar A, Njauw CN, Shannon K, Gragoudas ES, Marie Lane A, Iyer V, Newton-Bishop JA, Timothy Bishop D, Holland EA, Mann GJ, Singh T, Daly MJ, Tsao H. Rare Variant, Gene-Based Association Study of Hereditary Melanoma Using Whole-Exome Sequencing. J Natl Cancer Inst. 2017 12 01; 109(12). PMID: 29522175.
    Citations: 13     Fields:    Translation:Humans
  35. Haugh AM, Njauw CN, Bubley JA, Verzì AE, Zhang B, Kudalkar E, VandenBoom T, Walton K, Swick BL, Kumar R, Rana HQ, Cochrane S, McCormick SR, Shea CR, Tsao H, Gerami P. Genotypic and Phenotypic Features of BAP1 Cancer Syndrome: A Report of 8 New Families and Review of Cases in the Literature. JAMA Dermatol. 2017 10 01; 153(10):999-1006. PMID: 28793149.
    Citations: 29     Fields:    Translation:Humans
  36. Reddy BY, Miller DM, Tsao H. Somatic driver mutations in melanoma. Cancer. 2017 06 01; 123(S11):2104-2117. PMID: 28543693.
    Citations: 40     Fields:    Translation:Humans
  37. Tsao H. Introduction to JID's Landmarks in the Molecular Revolution. J Invest Dermatol. 2017 05; 137(5):996. PMID: 28411838.
    Citations:    Fields:    Translation:Humans
  38. Roh MR, Eliades P, Gupta S, Grant-Kels JM, Tsao H. Cutaneous melanoma in women. Int J Womens Dermatol. 2017 Mar; 3(1 Suppl):S11-S15. PMID: 28492033.
    Citations: 13     
  39. Tsao H, Fukunaga-Kalabis M, Herlyn M. Recent Advances in Melanoma and Melanocyte Biology. J Invest Dermatol. 2017 03; 137(3):557-560. PMID: 28089201.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  40. Torres A, Tsao H. Commentary: American Academy of Dermatology free skin cancer screening: 30 years of value. J Am Acad Dermatol. 2017 Jan; 76(1):181-182. PMID: 27986146.
    Citations:    Fields:    Translation:Humans
  41. Roh MR, Park KH, Chung KY, Shin SJ, Rha SY, Tsao H. Telomerase reverse transcriptase (TERT) promoter mutations in Korean melanoma patients. Am J Cancer Res. 2017; 7(1):134-138. PMID: 28123854.
    Citations: 6     
  42. Wang H, Osseiran S, Igras V, Nichols AJ, Roider EM, Pruessner J, Tsao H, Fisher DE, Evans CL. In vivo coherent Raman imaging of the melanomagenesis-associated pigment pheomelanin. Sci Rep. 2016 11 28; 6:37986. PMID: 27892516.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  43. Soura E, Stratigos AJ, Tsao H. Reply to: "The absence of multiple atypical nevi in germline CDKN2A mutations". J Am Acad Dermatol. 2016 10; 75(4):e159. PMID: 27646764.
    Citations:    Fields:    Translation:Humans
  44. Eliades P, Tsao H. New Insights into the Molecular Distinction of Dysplastic Nevi and Common Melanocytic Nevi-Highlighting the Keratinocyte-Melanocyte Relationship. J Invest Dermatol. 2016 10; 136(10):1933-1935. PMID: 27664709.
    Citations: 2     Fields:    Translation:HumansCells
  45. Ratushny V, Kraft S, Moschella SL, Duncan LM, Lawrence DP, Tsao H. A Symmetric Eczematous Eruption Harboring Thousands of Melanocytic Lesions. JAMA Dermatol. 2016 09 01; 152(9):1021-4. PMID: 27192392.
    Citations:    Fields:    Translation:Humans
  46. Tsao H, Weinstock MA. Visual Inspection and the US Preventive Services Task Force Recommendation on Skin Cancer Screening. JAMA. 2016 Jul 26; 316(4):398-400. PMID: 27458944.
    Citations: 6     Fields:    Translation:Humans
  47. Eliades P, Miller DM, Miao B, Kumar R, Taylor M, Buch S, Srinivasa SP, Flaherty KT, Tsao H. A novel multi-CDK inhibitor P1446A-05 restricts melanoma growth and produces synergistic effects in combination with MAPK pathway inhibitors. Cancer Biol Ther. 2016 07 02; 17(7):778-84. PMID: 26810603.
    Citations: 1     Fields:    Translation:HumansCells
  48. Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, Atkins MB, Bosenberg MW, Dummer R, Gershenwald JE, Halpern AC, Herlyn D, Karakousis GC, Kirkwood JM, Krauthammer M, Lo RS, Long GV, McArthur G, Ribas A, Schuchter L, Sosman JA, Smalley KS, Steeg P, Thomas NE, Tsao H, Tueting T, Weeraratna A, Xu G, Lomax R, Martin A, Silverstein S, Turnham T, Ronai ZA. The state of melanoma: challenges and opportunities. Pigment Cell Melanoma Res. 2016 07; 29(4):404-16. PMID: 27087480.
    Citations: 37     Fields:    Translation:HumansCells
  49. Wu JW, Turcotte R, Alt C, Runnels JM, Tsao H, Lin CP. Defining Clonal Color in Fluorescent Multi-Clonal Tracking. Sci Rep. 2016 Apr 13; 6:24303. PMID: 27073117.
    Citations: 6     Fields:    Translation:Cells
  50. Soura E, Eliades PJ, Shannon K, Stratigos AJ, Tsao H. Hereditary melanoma: Update on syndromes and management: Emerging melanoma cancer complexes and genetic counseling. J Am Acad Dermatol. 2016 Mar; 74(3):411-20; quiz 421-2. PMID: 26892651.
    Citations: 20     Fields:    Translation:HumansCells
  51. Soura E, Eliades PJ, Shannon K, Stratigos AJ, Tsao H. Hereditary melanoma: Update on syndromes and management: Genetics of familial atypical multiple mole melanoma syndrome. J Am Acad Dermatol. 2016 Mar; 74(3):395-407; quiz 408-10. PMID: 26892650.
    Citations: 47     Fields:    Translation:Humans
  52. Roh MR, Gupta S, Park KH, Chung KY, Lauss M, Flaherty KT, Jönsson G, Rha SY, Tsao H. Promoter Methylation of PTEN Is a Significant Prognostic Factor in Melanoma Survival. J Invest Dermatol. 2016 05; 136(5):1002-1011. PMID: 26854490.
    Citations: 25     Fields:    Translation:HumansCells
  53. Roh MR, Eliades P, Gupta S, Tsao H. Genetics of melanocytic nevi. Pigment Cell Melanoma Res. 2015 Nov; 28(6):661-72. PMID: 26300491.
    Citations: 34     Fields:    Translation:Humans
  54. Gerami P, Yélamos O, Lee CY, Obregon R, Yazdan P, Sholl LM, Guitart GE, Njauw CN, Tsao H. Multiple Cutaneous Melanomas and Clinically Atypical Moles in a Patient With a Novel Germline BAP1 Mutation. JAMA Dermatol. 2015 Nov; 151(11):1235-9. PMID: 26154183.
    Citations: 5     Fields:    Translation:Humans
  55. Gerami P, Tsao H. Concerns About Presence of a Wild-Type BAP1 Allele in Absence of Nuclear Protein Expression-Reply. JAMA Dermatol. 2015 Nov; 151(11):1266. PMID: 26559348.
    Citations:    Fields:    Translation:Humans
  56. Tsao H, Begolka WS. Reply to: "time to move forward after the report of the AAD Task Force for the ABCDEs of Melanoma". J Am Acad Dermatol. 2015 Oct; 73(4):e151. PMID: 26369859.
    Citations:    Fields:    Translation:Humans
  57. Gupta S, Artomov M, Goggins W, Daly M, Tsao H. Gender Disparity and Mutation Burden in Metastatic Melanoma. J Natl Cancer Inst. 2015 Nov; 107(11). PMID: 26296643.
    Citations: 45     Fields:    Translation:Humans
  58. Ho AW, Tsao H. Targeted Therapies in Melanoma: Translational Research at Its Finest. J Invest Dermatol. 2015 Aug; 135(8):1929-1933. PMID: 26174532.
    Citations: 7     Fields:    Translation:Humans
  59. Tsao H, Begolka WS. Reply to: "The ABCDs of melanoma-A complicated morphologic message not intended for the general public". J Am Acad Dermatol. 2015 Aug; 73(2):e61. PMID: 26183999.
    Citations:    Fields:    Translation:Humans
  60. Cirenajwis H, Ekedahl H, Lauss M, Harbst K, Carneiro A, Enoksson J, Rosengren F, Werner-Hartman L, Törngren T, Kvist A, Fredlund E, Bendahl PO, Jirström K, Lundgren L, Howlin J, Borg Å, Gruvberger-Saal SK, Saal LH, Nielsen K, Ringnér M, Tsao H, Olsson H, Ingvar C, Staaf J, Jönsson G. Molecular stratification of metastatic melanoma using gene expression profiling: Prediction of survival outcome and benefit from molecular targeted therapy. Oncotarget. 2015 May 20; 6(14):12297-309. PMID: 25909218.
    Citations: 78     Fields:    Translation:HumansCells
  61. Eliades P, Flaherty KT, Tsao H. Oncogene-directed small molecule inhibitors for the treatment of cutaneous melanoma. Melanoma Manag. 2015 May; 2(2):133-147. PMID: 30190843.
    Citations:    
  62. Luo S, Lobo AZ, Tanabe KK, Muzikansky A, Durazzo T, Sober A, Tsao H, Cosimi AB, Lawrence DP, Duncan LM. Clinical significance of microscopic melanoma metastases in the nonhottest sentinel lymph nodes. JAMA Surg. 2015 May; 150(5):465-72. PMID: 25831227.
    Citations: 2     Fields:    Translation:Humans
  63. Ji Z, Erin Chen Y, Kumar R, Taylor M, Jenny Njauw CN, Miao B, Frederick DT, Wargo JA, Flaherty KT, Jönsson G, Tsao H. MITF Modulates Therapeutic Resistance through EGFR Signaling. J Invest Dermatol. 2015 Jul; 135(7):1863-1872. PMID: 25789707.
    Citations: 37     Fields:    Translation:HumansCells
  64. Tsao H, Olazagasti JM, Cordoro KM, Brewer JD, Taylor SC, Bordeaux JS, Chren MM, Sober AJ, Tegeler C, Bhushan R, Begolka WS. Early detection of melanoma: reviewing the ABCDEs. J Am Acad Dermatol. 2015 Apr; 72(4):717-23. PMID: 25698455.
    Citations: 16     Fields:    Translation:Humans
  65. Roh MR, Eliades P, Gupta S, Tsao H. Cutaneous Melanoma in Women. Int J Womens Dermatol. 2015 Feb 01; 1(1):21-25. PMID: 25844396.
    Citations: 3     
  66. Paraiso KH, Das Thakur M, Fang B, Koomen JM, Fedorenko IV, John JK, Tsao H, Flaherty KT, Sondak VK, Messina JL, Pasquale EB, Villagra A, Rao UN, Kirkwood JM, Meier F, Sloot S, Gibney GT, Stuart D, Tawbi H, Smalley KS. Ligand-independent EPHA2 signaling drives the adoption of a targeted therapy-mediated metastatic melanoma phenotype. Cancer Discov. 2015 Mar; 5(3):264-73. PMID: 25542447.
    Citations: 43     Fields:    Translation:HumansCells
  67. Miao B, Ji Z, Tan L, Taylor M, Zhang J, Choi HG, Frederick DT, Kumar R, Wargo JA, Flaherty KT, Gray NS, Tsao H. EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma. Cancer Discov. 2015 Mar; 5(3):274-87. PMID: 25542448.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  68. Kumar R, Taylor M, Miao B, Ji Z, Njauw JC, Jönsson G, Frederick DT, Tsao H. BAP1 has a survival role in cutaneous melanoma. J Invest Dermatol. 2015 Apr; 135(4):1089-1097. PMID: 25521456.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  69. Lin WM, Luo S, Muzikansky A, Lobo AZ, Tanabe KK, Sober AJ, Cosimi AB, Tsao H, Duncan LM. Outcome of patients with de novo versus nevus-associated melanoma. J Am Acad Dermatol. 2015 Jan; 72(1):54-8. PMID: 25440436.
    Citations: 21     Fields:    Translation:Humans
  70. Luo S, Tsao H. Epidermal, sebaceous, and melanocytic nevoid proliferations are spectrums of mosaic RASopathies. J Invest Dermatol. 2014 Oct; 134(10):2493-2496. PMID: 25219651.
    Citations: 2     Fields:    Translation:Humans
  71. Strazzula L, Vedak P, Hoang MP, Sober A, Tsao H, Kroshinsky D. The utility of re-excising mildly and moderately dysplastic nevi: a retrospective analysis. J Am Acad Dermatol. 2014 Dec; 71(6):1071-6. PMID: 25262175.
    Citations: 5     Fields:    Translation:HumansCells
  72. Hawryluk EB, Tsao H. Melanoma: clinical features and genomic insights. Cold Spring Harb Perspect Med. 2014 Sep 02; 4(9):a015388. PMID: 25183853.
    Citations: 21     Fields:    Translation:Humans
  73. Miller DM, Flaherty KT, Tsao H. Current status and future directions of molecularly targeted therapies and immunotherapies for melanoma. Semin Cutan Med Surg. 2014 Jun; 33(2):60-7. PMID: 25085663.
    Citations: 5     Fields:    Translation:Humans
  74. Yonekawa Y, Kim IK, Gragoudas ES, Njauw CN, Tsao H, Jakobiec FA, Stacy RC. Aggressive skull base metastasis from uveal melanoma: a clinicopathologic study. Eur J Ophthalmol. 2014 Sep-Oct; 24(5):811-3. PMID: 24729140.
    Citations: 2     Fields:    Translation:Humans
  75. Miller DM, Flaherty KT, Tsao H. Commentary: Molecular testing in melanoma. J Am Acad Dermatol. 2014 May; 70(5):863-70. PMID: 24534656.
    Citations: 1     Fields:    Translation:Humans
  76. Marzuka-Alcalá A, Gabree MJ, Tsao H. Melanoma susceptibility genes and risk assessment. Methods Mol Biol. 2014; 1102:381-93. PMID: 24258989.
    Citations: 8     Fields:    Translation:Humans
  77. Redmond RW, Rajadurai A, Udayakumar D, Sviderskaya EV, Tsao H. Melanocytes are selectively vulnerable to UVA-mediated bystander oxidative signaling. J Invest Dermatol. 2014 Apr; 134(4):1083-1090. PMID: 24335898.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  78. Ji Z, Kumar R, Taylor M, Rajadurai A, Marzuka-Alcalá A, Chen YE, Njauw CN, Flaherty K, Jönsson G, Tsao H. Vemurafenib synergizes with nutlin-3 to deplete survivin and suppresses melanoma viability and tumor growth. Clin Cancer Res. 2013 Aug 15; 19(16):4383-91. PMID: 23812671.
    Citations: 19     Fields:    Translation:HumansAnimals
  79. Salas Fragomeni RA, Chung HW, Landesman Y, Senapedis W, Saint-Martin JR, Tsao H, Flaherty KT, Shacham S, Kauffman M, Cusack JC. CRM1 and BRAF inhibition synergize and induce tumor regression in BRAF-mutant melanoma. Mol Cancer Ther. 2013 Jul; 12(7):1171-9. PMID: 23615632.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  80. Chen YE, Tsao H. The skin microbiome: current perspectives and future challenges. J Am Acad Dermatol. 2013 Jul; 69(1):143-55. PMID: 23489584.
    Citations: 43     Fields:    Translation:HumansAnimals
  81. Bis S, Tsao H. Melanoma genetics: the other side. Clin Dermatol. 2013 Mar-Apr; 31(2):148-55. PMID: 23438378.
    Citations: 5     Fields:    Translation:HumansCells
  82. Chen ST, Geller AC, Tsao H. Update on the Epidemiology of Melanoma. Curr Dermatol Rep. 2013 Mar 01; 2(1):24-34. PMID: 23580930.
    Citations: 29     
  83. Puntervoll HE, Yang XR, Vetti HH, Bachmann IM, Avril MF, Benfodda M, Catricalà C, Dalle S, Duval-Modeste AB, Ghiorzo P, Grammatico P, Harland M, Hayward NK, Hu HH, Jouary T, Martin-Denavit T, Ozola A, Palmer JM, Pastorino L, Pjanova D, Soufir N, Steine SJ, Stratigos AJ, Thomas L, Tinat J, Tsao H, Veinalde R, Tucker MA, Bressac-de Paillerets B, Newton-Bishop JA, Goldstein AM, Akslen LA, Molven A. Melanoma prone families with CDK4 germline mutation: phenotypic profile and associations with MC1R variants. J Med Genet. 2013 Apr; 50(4):264-70. PMID: 23384855.
    Citations: 49     Fields:    Translation:Humans
  84. Lobo AZ, Tanabe KK, Luo S, Muzikansky A, Sober AJ, Tsao H, Cosimi AB, Duncan LM. The distribution of microscopic melanoma metastases in sentinel lymph nodes: implications for pathology protocols. Am J Surg Pathol. 2012 Dec; 36(12):1841-8. PMID: 23154770.
    Citations: 3     Fields:    Translation:Humans
  85. Nikolaou V, Stratigos AJ, Tsao H. Hereditary nonmelanoma skin cancer. Semin Cutan Med Surg. 2012 Dec; 31(4):204-10. PMID: 23174490.
    Citations: 16     Fields:    Translation:Humans
  86. Hung T, Piris A, Lobo A, Mihm MC, Sober AJ, Tsao H, Tanabe KK, Duncan LM. Sentinel lymph node metastasis is not predictive of poor outcome in patients with problematic spitzoid melanocytic tumors. Hum Pathol. 2013 Jan; 44(1):87-94. PMID: 22939951.
    Citations: 10     Fields:    Translation:HumansCells
  87. Harbst K, Staaf J, Lauss M, Karlsson A, Måsbäck A, Johansson I, Bendahl PO, Vallon-Christersson J, Törngren T, Ekedahl H, Geisler J, Höglund M, Höglund M, Ringnér M, Ringnér M, Lundgren L, Jirström K, Olsson H, Ingvar C, Borg Å, Tsao H, Jönsson G. Molecular profiling reveals low- and high-grade forms of primary melanoma. Clin Cancer Res. 2012 Aug 01; 18(15):4026-36. PMID: 22675174.
    Citations: 52     Fields:    Translation:Humans
  88. Tsao H, Chin L, Garraway LA, Fisher DE. Melanoma: from mutations to medicine. Genes Dev. 2012 Jun 01; 26(11):1131-55. PMID: 22661227.
    Citations: 207     Fields:    Translation:HumansAnimalsCells
  89. Njauw CN, Kim I, Piris A, Gabree M, Taylor M, Lane AM, DeAngelis MM, Gragoudas E, Duncan LM, Tsao H. Germline BAP1 inactivation is preferentially associated with metastatic ocular melanoma and cutaneous-ocular melanoma families. PLoS One. 2012; 7(4):e35295. PMID: 22545102.
    Citations: 97     Fields:    Translation:Humans
  90. Hawryluk EB, Sober AJ, Piris A, Nazarian RM, Hoang MP, Tsao H, Mihm MC, Duncan LM. Histologically challenging melanocytic tumors referred to a tertiary care pigmented lesion clinic. J Am Acad Dermatol. 2012 Oct; 67(4):727-35. PMID: 22521204.
    Citations: 6     Fields:    Translation:Humans
  91. Nardi V, Song Y, Santamaria-Barria JA, Cosper AK, Lam Q, Faber AC, Boland GM, Yeap BY, Bergethon K, Scialabba VL, Tsao H, Settleman J, Ryan DP, Borger DR, Bhan AK, Hoang MP, Iafrate AJ, Cusack JC, Engelman JA, Dias-Santagata D. Activation of PI3K signaling in Merkel cell carcinoma. Clin Cancer Res. 2012 Mar 01; 18(5):1227-36. PMID: 22261808.
    Citations: 45     Fields:    Translation:HumansCells
  92. Nikolaou VA, Stratigos AJ, Flaherty KT, Tsao H. Melanoma: new insights and new therapies. J Invest Dermatol. 2012 Mar; 132(3 Pt 2):854-63. PMID: 22217739.
    Citations: 74     Fields:    Translation:HumansCells
  93. Luo S, Sepehr A, Tsao H. Spitz nevi and other Spitzoid lesions part II. Natural history and management. J Am Acad Dermatol. 2011 Dec; 65(6):1087-92. PMID: 22082839.
    Citations: 7     Fields:    Translation:Humans
  94. Luo S, Sepehr A, Tsao H. Spitz nevi and other Spitzoid lesions part I. Background and diagnoses. J Am Acad Dermatol. 2011 Dec; 65(6):1073-84. PMID: 22082838.
    Citations: 11     Fields:    Translation:Humans
  95. Yokoyama S, Woods SL, Boyle GM, Aoude LG, MacGregor S, Zismann V, Gartside M, Cust AE, Haq R, Harland M, Taylor JC, Duffy DL, Holohan K, Dutton-Regester K, Palmer JM, Bonazzi V, Stark MS, Symmons J, Law MH, Schmidt C, Lanagan C, O'Connor L, Holland EA, Schmid H, Maskiell JA, Jetann J, Ferguson M, Jenkins MA, Kefford RF, Giles GG, Armstrong BK, Aitken JF, Hopper JL, Whiteman DC, Pharoah PD, Easton DF, Dunning AM, Newton-Bishop JA, Montgomery GW, Martin NG, Mann GJ, Bishop DT, Tsao H, Trent JM, Fisher DE, Hayward NK, Brown KM. A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature. 2011 Nov 13; 480(7375):99-103. PMID: 22080950.
    Citations: 168     Fields:    Translation:HumansCells
  96. Enzler T, Sano Y, Choo MK, Cottam HB, Karin M, Tsao H, Park JM. Cell-selective inhibition of NF-?B signaling improves therapeutic index in a melanoma chemotherapy model. Cancer Discov. 2011 Nov; 1(6):496-507. PMID: 22389871.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  97. Ji Z, Njauw CN, Taylor M, Neel V, Flaherty KT, Tsao H. p53 rescue through HDM2 antagonism suppresses melanoma growth and potentiates MEK inhibition. J Invest Dermatol. 2012 Feb; 132(2):356-64. PMID: 21993556.
    Citations: 38     Fields:    Translation:HumansCells
  98. Ji Z, Flaherty KT, Tsao H. Targeting the RAS pathway in melanoma. Trends Mol Med. 2012 Jan; 18(1):27-35. PMID: 21962474.
    Citations: 27     Fields:    Translation:HumansCells
  99. Bichakjian CK, Halpern AC, Johnson TM, Foote Hood A, Grichnik JM, Swetter SM, Tsao H, Barbosa VH, Chuang TY, Duvic M, Ho VC, Sober AJ, Beutner KR, Bhushan R, Smith Begolka W. Guidelines of care for the management of primary cutaneous melanoma. American Academy of Dermatology. J Am Acad Dermatol. 2011 Nov; 65(5):1032-47. PMID: 21868127.
    Citations: 71     Fields:    Translation:Humans
  100. Chatzinasiou F, Lill CM, Kypreou K, Stefanaki I, Nicolaou V, Spyrou G, Evangelou E, Roehr JT, Kodela E, Katsambas A, Tsao H, Ioannidis JP, Bertram L, Stratigos AJ. Comprehensive field synopsis and systematic meta-analyses of genetic association studies in cutaneous melanoma. J Natl Cancer Inst. 2011 Aug 17; 103(16):1227-35. PMID: 21693730.
    Citations: 48     Fields:    Translation:Humans
  101. Sepehr A, Chao E, Trefrey B, Blackford A, Duncan LM, Flotte TJ, Sober A, Mihm MC, Tsao H. Long-term outcome of Spitz-type melanocytic tumors. Arch Dermatol. 2011 Oct; 147(10):1173-9. PMID: 21680758.
    Citations: 2     Fields:    Translation:Humans
  102. Lipworth AD, Park JM, Trefrey BL, Rubin KM, Geller AC, Sober AJ, Tsao H. Urgent access to a specialty care melanoma clinic is associated with a higher rate of melanoma detection. J Am Acad Dermatol. 2011 Jun; 64(6):1060-7. PMID: 21453985.
    Citations: 2     Fields:    Translation:Humans
  103. Luo S, Chaplin AC, Langley RG, Njauw CN, Duncan LM, Miller RA, Tsao H. Agminated segmental nevi demonstrating intranevic concordance of BRAF status. J Invest Dermatol. 2011 Mar; 131(3):788-90. PMID: 21160499.
    Citations: 2     Fields:    Translation:Humans
  104. Ko JM, Velez NF, Tsao H. Pathways to melanoma. Semin Cutan Med Surg. 2010 Dec; 29(4):210-7. PMID: 21277534.
    Citations: 8     Fields:    Translation:Humans
  105. Lang JM, Shennan M, Njauw JC, Luo S, Bishop JN, Harland M, Hayward NK, Tucker MA, Goldstein AM, Landi MT, Puig S, Gruis NA, Bergman W, Bianchi-Scarra G, Ghiorzo P, Hogg D, Tsao H. A flexible multiplex bead-based assay for detecting germline CDKN2A and CDK4 variants in melanoma-prone kindreds. J Invest Dermatol. 2011 Feb; 131(2):480-6. PMID: 21085193.
    Citations: 4     Fields:    Translation:Humans
  106. Tsao H, Tanabe KK, Lawrence DP, Piris A. Case records of the Massachusetts General Hospital. Case 30-2010. A 15-year-old boy with a recurrent skin lesion. N Engl J Med. 2010 Sep 30; 363(14):1352-60. PMID: 20879885.
    Citations:    Fields:    Translation:HumansCells
  107. Udayakumar D, Mahato B, Gabree M, Tsao H. Genetic determinants of cutaneous melanoma predisposition. Semin Cutan Med Surg. 2010 Sep; 29(3):190-5. PMID: 21051013.
    Citations: 7     Fields:    Translation:Humans
  108. Boni A, Cogdill AP, Dang P, Udayakumar D, Njauw CN, Sloss CM, Ferrone CR, Flaherty KT, Lawrence DP, Fisher DE, Tsao H, Wargo JA. Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function. Cancer Res. 2010 Jul 01; 70(13):5213-9. PMID: 20551059.
    Citations: 324     Fields:    Translation:HumansCells
  109. Feramisco JD, Tsao H, Siegel DH. Genetics for the practicing dermatologist. Semin Cutan Med Surg. 2010 Jun; 29(2):127-36. PMID: 20579602.
    Citations: 3     Fields:    Translation:HumansCells
  110. Sober AJ, Tsao H. Martin C. Mihm, Jr and the history of the Pigmented Lesion Clinic at the Massachusetts General Hospital. J Cutan Pathol. 2010 Apr; 37 Suppl 1:8-11. PMID: 20482670.
    Citations:    Fields:    Translation:Humans
  111. Ji Z, Flaherty KT, Tsao H. Molecular therapeutic approaches to melanoma. Mol Aspects Med. 2010 Apr; 31(2):194-204. PMID: 20176049.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  112. Wang W, Niendorf KB, Patel D, Blackford A, Marroni F, Sober AJ, Parmigiani G, Tsao H. Estimating CDKN2A carrier probability and personalizing cancer risk assessments in hereditary melanoma using MelaPRO. Cancer Res. 2010 Jan 15; 70(2):552-9. PMID: 20068151.
    Citations: 17     Fields:    Translation:Humans
  113. Yang G, Thieu K, Tsai KY, Piris A, Udayakumar D, Njauw CN, Ramoni MF, Tsao H. Dynamic gene expression analysis links melanocyte growth arrest with nevogenesis. Cancer Res. 2009 Dec 01; 69(23):9029-37. PMID: 19903842.
    Citations: 1     Fields:    Translation:HumansCells
  114. Udayakumar D, Tsao H. Moderate- to low-risk variant alleles of cutaneous malignancies and nevi: lessons from genome-wide association studies. Genome Med. 2009 Oct 27; 1(10):95. PMID: 19863770.
    Citations: 7     Fields:    
  115. Leachman SA, Carucci J, Kohlmann W, Banks KC, Asgari MM, Bergman W, Bianchi-Scarrà G, Brentnall T, Bressac-de Paillerets B, Bruno W, Curiel-Lewandrowski C, de Snoo FA, Debniak T, Demierre MF, Elder D, Goldstein AM, Grant-Kels J, Halpern AC, Ingvar C, Kefford RF, Lang J, MacKie RM, Mann GJ, Mueller K, Newton-Bishop J, Olsson H, Petersen GM, Puig S, Rigel D, Swetter SM, Tucker MA, Yakobson E, Zitelli JA, Tsao H. Selection criteria for genetic assessment of patients with familial melanoma. J Am Acad Dermatol. 2009 Oct; 61(4):677.e1-14. PMID: 19751883.
    Citations: 53     Fields:    Translation:Humans
  116. Sadreyev RI, Feramisco JD, Tsao H, Grishin NV. Phenotypic categorization of genetic skin diseases reveals new relations between phenotypes, genes and pathways. Bioinformatics. 2009 Nov 15; 25(22):2891-6. PMID: 19744994.
    Citations: 1     Fields:    Translation:HumansCells
  117. Park JM, Tsao H, Tsao S. Acquired bilateral nevus of Ota-like macules (Hori nevus): etiologic and therapeutic considerations. J Am Acad Dermatol. 2009 Jul; 61(1):88-93. PMID: 19539841.
    Citations: 2     Fields:    Translation:HumansCells
  118. Feramisco JD, Sadreyev RI, Murray ML, Grishin NV, Tsao H. Phenotypic and genotypic analyses of genetic skin disease through the Online Mendelian Inheritance in Man (OMIM) database. J Invest Dermatol. 2009 Nov; 129(11):2628-36. PMID: 19536140.
    Citations: 16     Fields:    Translation:Humans
  119. Udayakumar D, Tsao H. Melanoma genetics: an update on risk-associated genes. Hematol Oncol Clin North Am. 2009 Jun; 23(3):415-29, vii. PMID: 19464594.
    Citations: 12     Fields:    Translation:Humans
  120. Nelson AA, Tsao H. Melanoma and genetics. Clin Dermatol. 2009 Jan-Feb; 27(1):46-52. PMID: 19095153.
    Citations: 28     Fields:    Translation:Humans
  121. Sun BK, Tsao H. Small RNAs in development and disease. J Am Acad Dermatol. 2008 Nov; 59(5):725-37; quiz 738-40. PMID: 19119093.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  122. Hocker TL, Singh MK, Tsao H. Melanoma genetics and therapeutic approaches in the 21st century: moving from the benchside to the bedside. J Invest Dermatol. 2008 Nov; 128(11):2575-2595. PMID: 18927540.
    Citations: 58     Fields:    Translation:HumansCells
  123. Lin J, Hocker TL, Singh M, Tsao H. Genetics of melanoma predisposition. Br J Dermatol. 2008 Aug; 159(2):286-91. PMID: 18547303.
    Citations: 10     Fields:    Translation:Humans
  124. Sun BK, Tsao H. X-chromosome inactivation and skin disease. J Invest Dermatol. 2008 Dec; 128(12):2753-9. PMID: 18509358.
    Citations: 13     Fields:    Translation:HumansCells
  125. Harland M, Goldstein AM, Kukalizch K, Taylor C, Hogg D, Puig S, Badenas C, Gruis N, ter Huurne J, Bergman W, Hayward NK, Stark M, Tsao H, Tucker MA, Landi MT, Scarra GB, Ghiorzo P, Kanetsky PA, Elder D, Mann GJ, Holland EA, Bishop DT, Bishop JN. A comparison of CDKN2A mutation detection within the Melanoma Genetics Consortium (GenoMEL). Eur J Cancer. 2008 Jun; 44(9):1269-74. PMID: 18394881.
    Citations: 16     Fields:    Translation:Humans
  126. Friedman RJ, Gutkowicz-Krusin D, Farber MJ, Warycha M, Schneider-Kels L, Papastathis N, Mihm MC, Googe P, King R, Prieto VG, Kopf AW, Polsky D, Rabinovitz H, Oliviero M, Cognetta A, Rigel DS, Marghoob A, Rivers J, Johr R, Grant-Kels JM, Tsao H. The diagnostic performance of expert dermoscopists vs a computer-vision system on small-diameter melanomas. Arch Dermatol. 2008 Apr; 144(4):476-82. PMID: 18427041.
    Citations: 21     Fields:    Translation:Humans
  127. Zhang G, Njauw CN, Park JM, Naruse C, Asano M, Tsao H. EphA2 is an essential mediator of UV radiation-induced apoptosis. Cancer Res. 2008 Mar 15; 68(6):1691-6. PMID: 18339848.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  128. Park JM, Tsao H, Tsao S. Combined use of intense pulsed light and Q-switched ruby laser for complex dyspigmentation among Asian patients. Lasers Surg Med. 2008 Feb; 40(2):128-33. PMID: 18306166.
    Citations: 4     Fields:    Translation:Humans
  129. Feramisco JD, Cayce RL, Casey RL, Tsao H. Recent updates on genetics: teaching old dogmas new tricks. Pediatr Dermatol. 2008 Jan-Feb; 25(1):99-108. PMID: 18304166.
    Citations: 1     Fields:    Translation:HumansCells
  130. Somoano B, Tsao H. Genodermatoses with cutaneous tumors and internal malignancies. Dermatol Clin. 2008 Jan; 26(1):69-87, viii. PMID: 18023772.
    Citations:    Fields:    Translation:Humans
  131. McDermott U, Sharma SV, Dowell L, Greninger P, Montagut C, Lamb J, Archibald H, Raudales R, Tam A, Lee D, Rothenberg SM, Supko JG, Sordella R, Ulkus LE, Iafrate AJ, Maheswaran S, Njauw CN, Tsao H, Drew L, Hanke JH, Ma XJ, Erlander MG, Gray NS, Haber DA, Settleman J. Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. Proc Natl Acad Sci U S A. 2007 Dec 11; 104(50):19936-41. PMID: 18077425.
    Citations: 169     Fields:    Translation:HumansCells
  132. Jarell AD, Lawrence D, Tsao H. The RAS/mitogen activated protein (MAP) kinase pathway in melanoma biology and therapeutics. Biologics. 2007 Dec; 1(4):407-14. PMID: 19707310.
    Citations: 1     
  133. Singh M, Lin J, Hocker TL, Tsao H. Genetics of melanoma tumorigenesis. Br J Dermatol. 2008 Jan; 158(1):15-21. PMID: 18047516.
    Citations: 15     Fields:    Translation:HumansCells
  134. Tsao H, Florez JC. Introduction to genetic association studies. J Invest Dermatol. 2007 Oct; 127(10):2283-7. PMID: 17853910.
    Citations: 3     Fields:    Translation:Humans
  135. Yang G, Curley D, Bosenberg MW, Tsao H. Loss of xeroderma pigmentosum C (Xpc) enhances melanoma photocarcinogenesis in Ink4a-Arf-deficient mice. Cancer Res. 2007 Jun 15; 67(12):5649-57. PMID: 17575131.
    Citations: 16     Fields:    Translation:AnimalsCells
  136. Hocker T, Tsao H. Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants. Hum Mutat. 2007 Jun; 28(6):578-88. PMID: 17295241.
    Citations: 91     Fields:    Translation:Humans
  137. Tsai KY, Tsao H. Primer on the human genome. J Am Acad Dermatol. 2007 May; 56(5):719-35. PMID: 17437886.
    Citations:    Fields:    Translation:Humans
  138. Lang J, Hayward N, Goldgar D, Tsao H, Hogg D, Palmer J, Stark M, Tobias ES, MacKie R. The M53I mutation in CDKN2A is a founder mutation that predominates in melanoma patients with Scottish ancestry. Genes Chromosomes Cancer. 2007 Mar; 46(3):277-87. PMID: 17171691.
    Citations: 1     Fields:    Translation:HumansCells
  139. Goldstein AM, Chan M, Harland M, Gillanders EM, Hayward NK, Avril MF, Azizi E, Bianchi-Scarra G, Bishop DT, Bressac-de Paillerets B, Bruno W, Calista D, Cannon Albright LA, Demenais F, Elder DE, Ghiorzo P, Gruis NA, Hansson J, Hogg D, Holland EA, Kanetsky PA, Kefford RF, Landi MT, Lang J, Leachman SA, Mackie RM, Magnusson V, Mann GJ, Niendorf K, Newton Bishop J, Palmer JM, Puig S, Puig-Butille JA, de Snoo FA, Stark M, Tsao H, Tucker MA, Whitaker L, Yakobson E. High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL. Cancer Res. 2006 Oct 15; 66(20):9818-28. PMID: 17047042.
    Citations: 139     Fields:    Translation:HumansAnimalsCells
  140. Goldstein AM, Chan M, Harland M, Hayward NK, Demenais F, Bishop DT, Azizi E, Bergman W, Bianchi-Scarra G, Bruno W, Calista D, Albright LA, Chaudru V, Chompret A, Cuellar F, Elder DE, Ghiorzo P, Gillanders EM, Gruis NA, Hansson J, Hogg D, Holland EA, Kanetsky PA, Kefford RF, Landi MT, Lang J, Leachman SA, MacKie RM, Magnusson V, Mann GJ, Bishop JN, Palmer JM, Puig S, Puig-Butille JA, Stark M, Tsao H, Tucker MA, Whitaker L, Yakobson E. Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents. J Med Genet. 2007 Feb; 44(2):99-106. PMID: 16905682.
    Citations: 151     Fields:    Translation:Humans
  141. Yang G, Zhang G, Pittelkow MR, Ramoni M, Tsao H. Expression profiling of UVB response in melanocytes identifies a set of p53-target genes. J Invest Dermatol. 2006 Nov; 126(11):2490-506. PMID: 16888633.
    Citations: 38     Fields:    Translation:HumansCells
  142. Haluska FG, Tsao H, Wu H, Haluska FS, Lazar A, Goel V. Genetic alterations in signaling pathways in melanoma. Clin Cancer Res. 2006 Apr 01; 12(7 Pt 2):2301s-2307s. PMID: 16609049.
    Citations: 72     Fields:    Translation:HumansCells
  143. Stratigos AJ, Yang G, Dimisianos R, Nicolaou V, Stefanaki I, Katsambas AD, Tsao H. Germline CDKN2A mutations among Greek patients with early-onset and multiple primary cutaneous melanoma. J Invest Dermatol. 2006 Feb; 126(2):399-401. PMID: 16374456.
    Citations: 4     Fields:    Translation:Humans
  144. Niendorf KB, Tsao H. Cutaneous melanoma: family screening and genetic testing. Dermatol Ther. 2006 Jan-Feb; 19(1):1-8. PMID: 16405564.
    Citations: 6     Fields:    Translation:Humans
  145. Goggins W, Daniels GH, Tsao H. Elevation of thyroid cancer risk among cutaneous melanoma survivors. Int J Cancer. 2006 Jan 01; 118(1):185-8. PMID: 16049985.
    Citations: 10     Fields:    Translation:Humans
  146. Tsao H. The SNPs of RAF. J Invest Dermatol. 2005 Dec; 125(6):xiv-xv. PMID: 16354174.
    Citations:    Fields:    Translation:Humans
  147. Yang G, Rajadurai A, Tsao H. Recurrent patterns of dual RB and p53 pathway inactivation in melanoma. J Invest Dermatol. 2005 Dec; 125(6):1242-51. PMID: 16354195.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  148. Niendorf KB, Goggins W, Yang G, Tsai KY, Shennan M, Bell DW, Sober AJ, Hogg D, Tsao H. MELPREDICT: a logistic regression model to estimate CDKN2A carrier probability. J Med Genet. 2006 Jun; 43(6):501-6. PMID: 16169933.
    Citations: 9     Fields:    Translation:Humans
  149. Tsao H, Sober AJ. Melanoma treatment update. Dermatol Clin. 2005 Apr; 23(2):323-33. PMID: 15837158.
    Citations: 4     Fields:    Translation:Humans
  150. Somoano B, Niendorf KB, Tsao H. Hereditary cancer syndromes of the skin. Clin Dermatol. 2005 Jan-Feb; 23(1):85-106. PMID: 15708293.
    Citations:    Fields:    Translation:Humans
  151. Tsai KY, Tsao H. The genetics of skin cancer. Am J Med Genet C Semin Med Genet. 2004 Nov 15; 131C(1):82-92. PMID: 15468170.
    Citations: 16     Fields:    Translation:HumansCells
  152. Tsao H, Niendorf K. Genetic testing in hereditary melanoma. J Am Acad Dermatol. 2004 Nov; 51(5):803-8. PMID: 15523363.
    Citations: 8     Fields:    Translation:Humans
  153. Goggins W, Gao W, Tsao H. Association between female breast cancer and cutaneous melanoma. Int J Cancer. 2004 Sep 20; 111(5):792-4. PMID: 15252852.
    Citations: 23     Fields:    Translation:Humans
  154. Tsao H, Atkins MB, Sober AJ. Management of cutaneous melanoma. N Engl J Med. 2004 Sep 02; 351(10):998-1012. PMID: 15342808.
    Citations: 243     Fields:    Translation:HumansPHPublic Health
  155. Yang G, Niendorf KB, Tsao H. A novel methionine-53-valine mutation of p16 in a hereditary melanoma kindred. J Invest Dermatol. 2004 Sep; 123(3):574-5. PMID: 15304098.
    Citations: 3     Fields:    Translation:Humans
  156. Tsao H, Sober AJ, Niendorf KB, Zembowicz A. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 7-2004. A 48-year-old woman with multiple pigmented lesions and a personal and family history of melanoma. N Engl J Med. 2004 Feb 26; 350(9):924-32. PMID: 14985491.
    Citations:    Fields:    Translation:Humans
  157. Tsao H, Goel V, Wu H, Yang G, Haluska FG. Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma. J Invest Dermatol. 2004 Feb; 122(2):337-41. PMID: 15009714.
    Citations: 174     Fields:    Translation:HumansCells
  158. Tsao H, Feldman M, Fullerton JE, Sober AJ, Rosenthal D, Goggins W. Early detection of asymptomatic pulmonary melanoma metastases by routine chest radiographs is not associated with improved survival. Arch Dermatol. 2004 Jan; 140(1):67-70. PMID: 14732662.
    Citations: 10     Fields:    Translation:Humans
  159. Bevona C, Goggins W, Quinn T, Fullerton J, Tsao H. Cutaneous melanomas associated with nevi. Arch Dermatol. 2003 Dec; 139(12):1620-4; discussion 1624. PMID: 14676081.
    Citations: 50     Fields:    Translation:Humans
  160. Tsao H, Mihm MC, Sheehan C. PTEN expression in normal skin, acquired melanocytic nevi, and cutaneous melanoma. J Am Acad Dermatol. 2003 Nov; 49(5):865-72. PMID: 14576666.
    Citations: 31     Fields:    Translation:Humans
  161. Bevona C, Tannous Z, Tsao H. Dermal melanocytic proliferation with features of a plaque-type blue nevus and neurocristic hamartoma. J Am Acad Dermatol. 2003 Nov; 49(5):924-9. PMID: 14576682.
    Citations: 4     Fields:    Translation:HumansCells
  162. Tsao H, Bevona C, Goggins W, Quinn T. The transformation rate of moles (melanocytic nevi) into cutaneous melanoma: a population-based estimate. Arch Dermatol. 2003 Mar; 139(3):282-8. PMID: 12622618.
    Citations: 57     Fields:    Translation:Humans
  163. Goggins WB, Tsao H. A population-based analysis of risk factors for a second primary cutaneous melanoma among melanoma survivors. Cancer. 2003 Feb 01; 97(3):639-43. PMID: 12548605.
    Citations: 27     Fields:    Translation:Humans
  164. Rheinwald JG, Hahn WC, Ramsey MR, Wu JY, Guo Z, Tsao H, De Luca M, Catricalà C, O'Toole KM. A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status. Mol Cell Biol. 2002 Jul; 22(14):5157-72. PMID: 12077343.
    Citations: 115     Fields:    Translation:HumansCells
  165. Tsao H, Millman P, Linette GP, Hodi FS, Sober AJ, Goldberg MA, Haluska FG. Hypopigmentation associated with an adenovirus-mediated gp100/MART-1-transduced dendritic cell vaccine for metastatic melanoma. Arch Dermatol. 2002 Jun; 138(6):799-802. PMID: 12056962.
    Citations: 8     Fields:    Translation:HumansCells
  166. Tsao H, Kwitkiwski K, Sober AJ. A single-institution case series of patients with cutaneous melanoma and non-Hodgkin's lymphoma. J Am Acad Dermatol. 2002 Jan; 46(1):55-61. PMID: 11756946.
    Citations: 1     Fields:    Translation:Humans
  167. Tsao H. Genetics of nonmelanoma skin cancer. Arch Dermatol. 2001 Nov; 137(11):1486-92. PMID: 11708952.
    Citations: 9     Fields:    Translation:Humans
  168. Tsao H, Nadiminti U, Sober AJ, Bigby M. A meta-analysis of reverse transcriptase-polymerase chain reaction for tyrosinase mRNA as a marker for circulating tumor cells in cutaneous melanoma. Arch Dermatol. 2001 Mar; 137(3):325-30. PMID: 11255333.
    Citations: 13     Fields:    Translation:HumansCells
  169. Goggins WB, Finkelstein DM, Tsao H. Evidence for an association between cutaneous melanoma and non-Hodgkin lymphoma. Cancer. 2001 Feb 15; 91(4):874-80. PMID: 11241258.
    Citations: 14     Fields:    Translation:Humans
  170. Tsao H, Zhang X, Kwitkiwski K, Finkelstein DM, Sober AJ, Haluska FG. Low prevalence of germline CDKN2A and CDK4 mutations in patients with early-onset melanoma. Arch Dermatol. 2000 Sep; 136(9):1118-22. PMID: 10987867.
    Citations: 19     Fields:    Translation:Humans
  171. Tsao H, Lerner LH. Pigmented purpuric eruption associated with injection medroxyprogesterone acetate. J Am Acad Dermatol. 2000 Aug; 43(2 Pt 1):308-10. PMID: 10906656.
    Citations: 1     Fields:    Translation:Humans
  172. Tsao H. Update on familial cancer syndromes and the skin. J Am Acad Dermatol. 2000 Jun; 42(6):939-69; quiz 970-2. PMID: 10827397.
    Citations: 9     Fields:    Translation:Humans
  173. Jonasch E, Kumar UN, Linette GP, Hodi FS, Soiffer RJ, Ryan BF, Sober AJ, Mihm MC, Tsao H, Langley RG, Cosimi BA, Gadd MA, Tanabe KK, Souba W, Haynes HA, Barnhill R, Osteen R, Haluska FG. Adjuvant high-dose interferon alfa-2b in patients with high-risk melanoma. Cancer J. 2000 May-Jun; 6(3):139-45. PMID: 10882328.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  174. Tsao H, Zhang X, Fowlkes K, Haluska FG. Relative reciprocity of NRAS and PTEN/MMAC1 alterations in cutaneous melanoma cell lines. Cancer Res. 2000 Apr 01; 60(7):1800-4. PMID: 10766161.
    Citations: 78     Fields:    Translation:HumansAnimalsCells
  175. Tsao H. American Academy of Dermatology 1999 Awards for Young Investigators in Dermatology. Targets of genetic injury in cutaneous melanoma. J Am Acad Dermatol. 1999 Sep; 41(3 Pt 1):459-61. PMID: 10507912.
    Citations:    Fields:    Translation:HumansCells
  176. Tsao H, Tahan SR. Images in clinical medicine. Keratoacanthoma. N Engl J Med. 1999 Mar 04; 340(9):708. PMID: 10053180.
    Citations:    Fields:    Translation:Humans
  177. Zhang X, Tsao H, Tsuji T, Minoshima S, McBride J, Majewski P, Todd R, Shimizu N, Wong DT, Housman DE, Haluska FG. Identification and mutation analysis of DOC-1R, a DOC-1 growth suppressor-related gene. Biochem Biophys Res Commun. 1999 Feb 05; 255(1):59-63. PMID: 10082655.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  178. Tsao H, Zhang X, Majewski P, Haluska FG. Mutational and expression analysis of the p73 gene in melanoma cell lines. Cancer Res. 1999 Jan 01; 59(1):172-4. PMID: 9892203.
    Citations: 5     Fields:    Translation:HumansCells
  179. Tsao H, Sober AJ. Multiple lipomatosis in a patient with familial atypical mole syndrome. Br J Dermatol. 1998 Dec; 139(6):1118-9. PMID: 9990390.
    Citations:    Fields:    Translation:Humans
  180. Tsao H, Zhang X, Benoit E, Haluska FG. Identification of PTEN/MMAC1 alterations in uncultured melanomas and melanoma cell lines. Oncogene. 1998 Jul 02; 16(26):3397-402. PMID: 9692547.
    Citations: 67     Fields:    Translation:HumansCells
  181. Tsao H, Rogers GS, Sober AJ. An estimate of the annual direct cost of treating cutaneous melanoma. J Am Acad Dermatol. 1998 May; 38(5 Pt 1):669-80. PMID: 9591809.
    Citations: 22     Fields:    Translation:HumansPHPublic Health
  182. Lee PK, Rosenberg CN, Tsao H, Sober AJ. Failure of Q-switched ruby laser to eradicate atypical-appearing solar lentigo: report of two cases. J Am Acad Dermatol. 1998 Feb; 38(2 Pt 2):314-7. PMID: 9486705.
    Citations: 3     Fields:    Translation:HumansCells
  183. Tsao H, Sober AJ. Ultraviolet radiation and malignant melanoma. Clin Dermatol. 1998 Jan-Feb; 16(1):67-73. PMID: 9472435.
    Citations: 2     Fields:    Translation:HumansAnimals
  184. Tsao H, Benoit E, Sober AJ, Thiele C, Haluska FG. Novel mutations in the p16/CDKN2A binding region of the cyclin-dependent kinase-4 gene. Cancer Res. 1998 Jan 01; 58(1):109-13. PMID: 9426066.
    Citations: 17     Fields:    Translation:HumansCells
  185. Haluska FG, Thiele C, Goldstein A, Tsao H, Benoit EP, Housman D. Lack of phospholipase A2 mutations in neuroblastoma, melanoma and colon-cancer cell lines. Int J Cancer. 1997 Jul 17; 72(2):337-9. PMID: 9219842.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  186. Tsao H, Cosimi AB, Sober AJ. Ultra-late recurrence (15 years or longer) of cutaneous melanoma. Cancer. 1997 Jun 15; 79(12):2361-70. PMID: 9191524.
    Citations: 30     Fields:    Translation:Humans
  187. Tsao H, Sober AJ, Barnhill RL. Desmoplastic neurotropic melanoma. Semin Cutan Med Surg. 1997 Jun; 16(2):131-6. PMID: 9220552.
    Citations: 3     Fields:    Translation:Humans
  188. Tsao H, Tahan SR, Johnson RA. Chronic varicella zoster infection mimicking a basal cell carcinoma in an AIDS patient. J Am Acad Dermatol. 1997 May; 36(5 Pt 2):831-3. PMID: 9146560.
    Citations: 1     Fields:    Translation:Humans
  189. Luo SF, Chiu CT, Tsao HL, Fan LW, Tsai CT, Pan SL, Yang CM. Effect of forskolin on bradykinin-induced calcium mobilization in cultured canine tracheal smooth muscle cells. Cell Signal. 1997 Feb; 9(2):159-67. PMID: 9113415.
    Citations: 2     Fields:    Translation:AnimalsCells
  190. Tsao H, Busam K, Barnhill RL, Haynes HA. Lesions resembling malignant atrophic papulosis in a patient with dermatomyositis. J Am Acad Dermatol. 1997 Feb; 36(2 Pt 2):317-9. PMID: 9039209.
    Citations: 5     Fields:    Translation:Humans
  191. Tsao H, Busam K, Barnhill RL, Dover JS. Treatment of minocycline-induced hyperpigmentation with the Q-switched ruby laser. Arch Dermatol. 1996 Oct; 132(10):1250-1. PMID: 8859045.
    Citations: 2     Fields:    Translation:Humans
  192. de la Zerda A, Chiu-Tsao ST, Lin J, Boulay LL, Kanna I, Kim JH, Tsao HS. 125I eye plaque dose distribution including penumbra characteristics. Med Phys. 1996 Mar; 23(3):407-18. PMID: 8815384.
    Citations: 4     Fields:    Translation:Humans
  193. Luo SF, Tsao HL, Ong R, Hsieh JT, Yang CM. Inhibitory effect of phorbol ester on bradykinin-induced phosphoinositide hydrolysis and calcium mobilization in cultured canine tracheal smooth muscle cells. Cell Signal. 1995 Aug; 7(6):571-81. PMID: 8588973.
    Citations: 1     Fields:    Translation:AnimalsCells
  194. Loeb DM, Tsao H, Cobb MH, Greene LA. NGF and other growth factors induce an association between ERK1 and the NGF receptor, gp140prototrk. Neuron. 1992 Dec; 9(6):1053-65. PMID: 1463607.
    Citations: 19     Fields:    Translation:AnimalsCells
  195. Tsao H, Greene LA. The roles of macromolecular synthesis and phosphorylation in the regulation of a protein kinase activity transiently stimulated by nerve growth factor. J Biol Chem. 1991 Jul 15; 266(20):12981-8. PMID: 2071585.
    Citations: 7     Fields:    Translation:AnimalsCells
  196. Tsao H, Aletta JM, Greene LA. Nerve growth factor and fibroblast growth factor selectively activate a protein kinase that phosphorylates high molecular weight microtubule-associated proteins. Detection, partial purification, and characterization in PC12 cells. J Biol Chem. 1990 Sep 15; 265(26):15471-80. PMID: 2394735.
    Citations: 27     Fields:    Translation:AnimalsCells