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Alexander Spektor, M.D.,Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Umbreit NT, Zhang CZ, Lynch LD, Blaine LJ, Cheng AM, Tourdot R, Sun L, Almubarak HF, Judge K, Mitchell TJ, Spektor A, Pellman D. Mechanisms generating cancer genome complexity from a single cell division error. Science. 2020 04 17; 368(6488). PMID: 32299917.
    Citations:    
  2. Melms JC, Vallabhaneni S, Mills CE, Yapp C, Chen JY, Morelli E, Waszyk P, Kumar S, Deming D, Moret N, Rodriguez S, Subramanian K, Rogava M, Cartwright ANR, Luoma A, Mei S, Brinker TJ, Miller DM, Spektor A, Schadendorf D, Riggi N, Wucherpfennig KW, Sorger PK, Izar B. Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity. Cancer Res. 2020 02 15; 80(4):798-810. PMID: 31882401.
    Citations:    
  3. Huynh MA, Spektor A. Translational and basic science opportunities in palliative care and radiation oncology. Ann Palliat Med. 2019 Jul; 8(3):326-336. PMID: 31370663.
    Citations:    
  4. Yerramilli D, Parker G, LeBaron V, Krishnan M, Hertan L, Spektor A, Shiloh R, Skamene S, Balboni T. Ethical issues in patients referred for palliative radiation therapy. Ann Palliat Med. 2019 07; 8(3):231-239. PMID: 31370662.
    Citations:    
  5. Fareed MM, Pike LRG, Bang A, Huynh MA, Taylor A, Spektor A, Awad MM, Ott PA, Krishnan M, Balboni TA, Schoenfeld JD. Palliative Radiation Therapy for Vertebral Metastases and Metastatic Cord Compression in Patients Treated With Anti-PD-1 Therapy. Front Oncol. 2019; 9:199. PMID: 30984622.
    Citations:    
  6. Oser MG, Fonseca R, Chakraborty AA, Brough R, Spektor A, Jennings RB, Flaifel A, Novak JS, Gulati A, Buss E, Younger ST, McBrayer SK, Cowley GS, Bonal DM, Nguyen QD, Brulle-Soumare L, Taylor P, Cairo S, Ryan CJ, Pease EJ, Maratea K, Travers J, Root DE, Signoretti S, Pellman D, Ashton S, Lord CJ, Barry ST, Kaelin WG. Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival. Cancer Discov. 2019 02; 9(2):230-247. PMID: 30373918.
    Citations:    Fields:    
  7. Pike LRG, Bang A, Mahal BA, Taylor A, Krishnan M, Spektor A, Cagney DN, Aizer AA, Alexander BM, Rahma O, Balboni T, Ott PA, Hodi FS, Schoenfeld JD. The Impact of Radiation Therapy on Lymphocyte Count and Survival in Metastatic Cancer Patients Receiving PD-1 Immune Checkpoint Inhibitors. Int J Radiat Oncol Biol Phys. 2019 01 01; 103(1):142-151. PMID: 30227198.
    Citations:    Fields:    
  8. Skamene S, Agarwal I, Makar M, Krishnan M, Spektor A, Hertan L, Mouw KW, Taylor A, Noveroske Philbrick S, Balboni T. Impact of a dedicated palliative radiation oncology service on the use of single fraction and hypofractionated radiation therapy among patients with bone metastases. Ann Palliat Med. 2018 Apr; 7(2):186-191. PMID: 29307209.
    Citations:    Fields:    Translation:Humans
  9. Spektor A, Umbreit NT, Pellman D. Cell Biology: When Your Own Chromosomes Act like Foreign DNA. Curr Biol. 2017 11 20; 27(22):R1228-R1231. PMID: 29161564.
    Citations:    Fields:    
  10. Pike LRG, Bang A, Ott P, Balboni T, Taylor A, Catalano P, Rawal B, Spektor A, Krishnan M, Cagney D, Alexander B, Aizer AA, Buchbinder E, Awad M, Gandhi L, Hodi FS, Schoenfeld JD. Radiation and PD-1 inhibition: Favorable outcomes after brain-directed radiation. Radiother Oncol. 2017 07; 124(1):98-103. PMID: 28662869.
    Citations: 4     Fields:    Translation:Humans
  11. Parker GM, LeBaron VT, Krishnan M, Shiloh RY, Spektor A, Hertan L, Balboni TA. Burden of palliative care issues encountered by radiation oncologists caring for patients with advanced cancer. Pract Radiat Oncol. 2017 Nov - Dec; 7(6):e517-e524. PMID: 28688910.
    Citations:    Fields:    Translation:Humans
  12. Krishnan M, Racsa M, Jones J, Chittenden E, Schaefer KG, Spektor A, Enzinger A, Wei R, Balboni T. Radiation oncology resident palliative education. Pract Radiat Oncol. 2017 Nov - Dec; 7(6):e439-e448. PMID: 28462897.
    Citations:    Fields:    Translation:Humans
  13. Bang A, Wilhite TJ, Pike LRG, Cagney DN, Aizer AA, Taylor A, Spektor A, Krishnan M, Ott PA, Balboni TA, Hodi FS, Schoenfeld JD. Multicenter Evaluation of the Tolerability of Combined Treatment With PD-1 and CTLA-4 Immune Checkpoint Inhibitors and Palliative Radiation Therapy. Int J Radiat Oncol Biol Phys. 2017 06 01; 98(2):344-351. PMID: 28463153.
    Citations: 14     Fields:    Translation:Humans
  14. Balboni TA, Braunstein SE, Fogh SE, Anderson W, Pantilat S, Taylor A, Spektor A, Krishnan MS, Haas-Kogan DA, Hertan LM. Acute pain management in radiation oncology: Quality of care and the impact of an integrated palliative oncology service. J Clin Oncol. 2016 Oct 09; 34(26_suppl):195. PMID: 28156446.
    Citations:    
  15. Golden DW, Braunstein S, Jimenez RB, Mohindra P, Spektor A, Ye JC. Multi-Institutional Implementation and Evaluation of a Curriculum for the Medical Student Clerkship in Radiation Oncology. J Am Coll Radiol. 2016 Feb; 13(2):203-9. PMID: 26410347.
    Citations: 4     Fields:    Translation:Humans
  16. Ye JC, Mohindra P, Spektor A, Krishnan MS, Chmura SJ, Howard AR, Viswanathan AN, MacDonald SM, Thaker NG, Das P, Mancini BR, Higgins SA, Braunstein S, Haas-Kogan D, Bradley KA, Hung AY, Thomas CR, Kharofa J, Wheatley M, Currey A, Parashar B, Du K, Jimenez RB, Golden DW. Medical Student Perspectives on a Multi-institutional Clerkship Curriculum: A Report From the Radiation Oncology Education Collaborative Study Group. Int J Radiat Oncol Biol Phys. 2015 Jun 01; 92(2):217-9. PMID: 25968822.
    Citations: 2     Fields:    Translation:Humans
  17. Chandra RA, Wilhite TJ, Balboni TA, Alexander BM, Spektor A, Ott PA, Ng AK, Hodi FS, Schoenfeld JD. A systematic evaluation of abscopal responses following radiotherapy in patients with metastatic melanoma treated with ipilimumab. Oncoimmunology. 2015 Nov; 4(11):e1046028. PMID: 26451318.
    Citations: 35     
  18. Zhang CZ, Spektor A, Cornils H, Francis JM, Jackson EK, Liu S, Meyerson M, Pellman D. Chromothripsis from DNA damage in micronuclei. Nature. 2015 Jun 11; 522(7555):179-84. PMID: 26017310.
    Citations: 143     Fields:    Translation:HumansCells
  19. LeBaron V, Krishnan MS, Shiloh RY, Racsa M, Pacold ME, Spektor A, Balboni TA. Palliative care issues encountered by radiation oncologists caring for advanced cancer patients. J Clin Oncol. 2014 Nov; 32(31_suppl):14. PMID: 28142689.
    Citations:    
  20. Golden DW, Spektor A, Rudra S, Ranck MC, Krishnan MS, Jimenez RB, Viswanathan AN, Koshy M, Howard AR, Chmura SJ. Radiation oncology medical student clerkship: implementation and evaluation of a bi-institutional pilot curriculum. Int J Radiat Oncol Biol Phys. 2014 Jan 01; 88(1):45-50. PMID: 24331650.
    Citations: 6     Fields:    Translation:Humans
  21. Kohlmaier G, Loncarek J, Meng X, McEwen BF, Mogensen MM, Spektor A, Dynlacht BD, Khodjakov A, Gönczy P. Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP. Curr Biol. 2009 Jun 23; 19(12):1012-8. PMID: 19481460.
    Citations: 96     Fields:    Translation:HumansAnimalsCells
  22. Tsang WY, Spektor A, Vijayakumar S, Bista BR, Li J, Sanchez I, Duensing S, Dynlacht BD. Cep76, a centrosomal protein that specifically restrains centriole reduplication. Dev Cell. 2009 May; 16(5):649-60. PMID: 19460342.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  23. Spektor A, Tsang WY, Khoo D, Dynlacht BD. Cep97 and CP110 suppress a cilia assembly program. Cell. 2007 Aug 24; 130(4):678-90. PMID: 17719545.
    Citations:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.