Title Associate Professor of Psychiatry Institution McLean Hospital Address McLean Hospital Brain Imaging Center 115 Mill St Belmont MA 02478
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Biography
1997 - 2002
Mentored Career Development Award (K01), NIDA
1998 - 1998
Alfred Pope Award for Young Investigators, McLean Hospital
2004 - 2009
Independent Scientist Award (K02), NIDA
2010 - 2010
Jack H. Mendelson Memorial Research Award, McLean Hospital
2011 - 2012
Rapid Response Innovation Award, Michael J. Fox Foundation for Parkinson's Research
2011 - 2013
Independent Investigator Award, NARSAD
2013 - 2017
Board of Directors, College on Problems of Drug Dependence
2015 - 2018
Charter Member, NIH Addiction Risks and Mechanisms Study Section
2020 - 2020
SUD Startup 2020 Competition Award

Overview
My primary scientific aim is to establish translational neuroimaging models to develop novel treatments for addiction, psychiatric, and neurodegenerative disorders. I maintain active clinical and preclinical neuroimaging programs involving magnetic resonance imaging (MRI), functional MRI (fMRI), and magnetic resonance spectroscopy (MRS) studies relevant to substance dependence, schizophrenia, PTSD, and Parkinson’s Disease. I am Director of the Translational Imaging Laboratory at McLean Hospital. I oversee implementation and optimization of animal imaging protocols that form a translational bridge to human neuroimaging studies. I recently initiated research into novel survey and biomarker methods to identify individuals at risk for suicide.
I serve as a Member of Institutional Review Board 1 of the Partners Human Research Committee.
I actively participate as a mentor of young investigators at McLean Hospital and elsewhere. I am a Co-Director of the Training in Drug Abuse and Brain Imaging T32 postdoctoral program (PI: Lukas).
I am very interested in scientific communications and served as a member of the Media Relations Committee for the College on Problems of Drug Dependence (CPDD). I served as Chair of that Committee from 2005-2013 and subsequently on the Board of Directors of the College.
In summary, my aims are to use neuroimaging to better diagnose and treat addiction, psychiatric, and neurodegenerative disorders, to mentor and train the next generation of neuroimaging researchers, and to improve communication of scientific information to the public.

Research
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R41DA055403
(BOGIN, VLAD)
Sep 30, 2021 - Sep 29, 2022
Portable hand-held proprietary xenon inhaler for rapid reduction of opioid withdrawal symptoms
Role: Co-Principal Investigator
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U18DA052344
(KAUFMAN, MARC J)
Sep 30, 2020 - Sep 29, 2021
Dimethyl fumarate attenuation of opioid withdrawal symptom severity
Role: Principal Investigator
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R01DA041866
(KAUFMAN, MARC J)
Sep 1, 2017 - Jun 30, 2022
Brain effects of long-term anabolic-androgenic steroid use:Multimodal imaging and cognition studies
Role: Principal Investigator
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R21DA039301
(KAUFMAN, MARC J)
Sep 15, 2015 - Feb 28, 2018
Effects of chronic cocaine on cognition and glutamate levels in nonhuman primates
Role: Principal Investigator
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R01DA039044
(MCLAUGHLIN, JAY P.)
Aug 1, 2015 - May 31, 2021
HIV Tat protein mediation of neurochemical changes and increased opioid reward
Role: Principal Investigator
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R03NS080073
(KAUFMAN, MARC J)
Jul 1, 2012 - Jun 30, 2014
Is xenon neuroprotective in a mouse model of ALS
Role: Principal Investigator
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R21DA031925
(KAUFMAN, MARC J)
Apr 15, 2012 - Mar 31, 2016
Concurrent PET D2/D3 receptor imaging and fMRI smoking cue reactivity in smokers
Role: Principal Investigator
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S10RR019356
(KAUFMAN, MARC J)
May 1, 2004 - Aug 31, 2007
Ultra High Field 9.4T Animal Magnetic Resonance Scanner
Role: Principal Investigator
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K02DA017324
(KAUFMAN, MARC J)
Mar 15, 2004 - Feb 28, 2009
Chronic drug exposures in monkeys: serial MRI studies
Role: Principal Investigator
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R01DA014674
(KAUFMAN, MARC J)
Aug 1, 2002 - Jul 31, 2008
Cocaine &Steroids: Brain Vascular &Behavioral Effects
Role: Principal Investigator
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K01DA000329
(KAUFMAN, MARC J)
May 1, 1997 - Apr 30, 2003
MR SPECTROSCOPIC IMAGING OF STIMULANT ABUSE
Role: Principal Investigator
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R01DA009448
(KAUFMAN, MARC J)
Sep 30, 1994 - Aug 31, 2010
Magnetic Resonance, EEG, and Behavior After Cocaine
Role: Principal Investigator

Bibliographic
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