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profileDavid Steven Pellman, M.D.

TitleMargaret M. Dyson Professor of Pediatric Oncology
InstitutionDana-Farber Cancer Institute
DepartmentPediatrics
AddressDana Farber Cancer Institute
M 621a
44 Binney St
Boston MA 02115
Phone617/632-4918
Fax617/632-5757
vCardDownload vCard (login for email)
Other Positions
TitleProfessor of Cell Biology
InstitutionDana-Farber Cancer Institute
DepartmentCell Biology


Collapse Mentoring 
Collapse completed student projects
Defining the mechanism underlying micronuclei-mediated mutagenesis in cancer
Summer, 06/16/14 - 08/01/14

Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R13CA177028     (PELLMAN, DAVID S)May 1, 2013 - Apr 30, 2014
NIH/NCI
2013 Cell Growth and Proliferation GRC/GRS
Role: Principal Investigator

R37GM061345     (PELLMAN, DAVID S)Jul 1, 2000 - Jul 31, 2019
NIH/NIGMS
Cell Cycle Control of the Cytoskeleton
Role: Principal Investigator

R01GM061345     (PELLMAN, DAVID S)Jul 1, 2000 - Jul 31, 2013
NIH/NIGMS
Cell Cycle Control of the Cytoskeleton
Role: Principal Investigator

R01CA213404     (PELLMAN, DAVID S)May 1, 1997 - Nov 30, 2021
NIH/NCI
Polyploidy, aneuploidy, and genome stability
Role: Principal Investigator

R01GM083299     (PELLMAN, DAVID S)May 1, 1997 - May 31, 2016
NIH/NIGMS
Polyploidy, aneuploidy and genome stability
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Arellano-Santoyo H, Geyer EA, Stokasimov E, Chen GY, Su X, Hancock W, Rice LM, Pellman D. A Tubulin Binding Switch Underlies Kip3/Kinesin-8 Depolymerase Activity. Dev Cell. 2017 Jul 10; 42(1):37-51.e8. PMID: 28697331.
    View in: PubMed
  2. Li H, Mar BG, Zhang H, Puram RV, Vazquez F, Weir BA, Hahn WC, Ebert B, Pellman D. The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia. Blood. 2017 Jan 26; 129(4):497-508. PMID: 27756750.
    View in: PubMed
  3. Zhang CZ, Pellman D. From Mutational Mechanisms in Single Cells to Mutational Patterns in Cancer Genomes. Cold Spring Harb Symp Quant Biol. 2015; 80:117-37. PMID: 26968629.
    View in: PubMed
  4. Gordon DJ, Motwani M, Pellman D. Modeling the initiation of Ewing sarcoma tumorigenesis in differentiating human embryonic stem cells. Oncogene. 2016 Jun 16; 35(24):3092-102. PMID: 26455317; PMCID: PMC4829493.
  5. Leibowitz ML, Zhang CZ, Pellman D. Chromothripsis: A New Mechanism for Rapid Karyotype Evolution. Annu Rev Genet. 2015; 49:183-211. PMID: 26442848.
    View in: PubMed
  6. Kwon M, Bagonis M, Danuser G, Pellman D. Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds. Dev Cell. 2015 Aug 10; 34(3):323-37. PMID: 26235048; PMCID: PMC4672950.
  7. Zhang CZ, Spektor A, Cornils H, Francis JM, Jackson EK, Liu S, Meyerson M, Pellman D. Chromothripsis from DNA damage in micronuclei. Nature. 2015 Jun 11; 522(7555):179-84. PMID: 26017310; PMCID: PMC4742237.
  8. Selmecki AM, Maruvka YE, Richmond PA, Guillet M, Shoresh N, Sorenson AL, De S, Kishony R, Michor F, Dowell R, Pellman D. Polyploidy can drive rapid adaptation in yeast. Nature. 2015 Mar 19; 519(7543):349-52. PMID: 25731168; PMCID: PMC4497379.
  9. Cowley GS, Weir BA, Vazquez F, Tamayo P, Scott JA, Rusin S, East-Seletsky A, Ali LD, Gerath WF, Pantel SE, Lizotte PH, Jiang G, Hsiao J, Tsherniak A, Dwinell E, Aoyama S, Okamoto M, Harrington W, Gelfand E, Green TM, Tomko MJ, Gopal S, Wong TC, Li H, Howell S, Stransky N, Liefeld T, Jang D, Bistline J, Meyers BH, Armstrong SA, Anderson KC, Stegmaier K, Reich M, Pellman D, Boehm JS, Mesirov JP, Golub TR, Root DE, Hahn WC. Erratum: Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies. Sci Data. 2014; 1:140044. PMID: 25982629; PMCID: PMC4411007.
  10. Cowley GS, Weir BA, Vazquez F, Tamayo P, Scott JA, Rusin S, East-Seletsky A, Ali LD, Gerath WF, Pantel SE, Lizotte PH, Jiang G, Hsiao J, Tsherniak A, Dwinell E, Aoyama S, Okamoto M, Harrington W, Gelfand E, Green TM, Tomko MJ, Gopal S, Wong TC, Wong TC, Li H, Howell S, Stransky N, Liefeld T, Jang D, Bistline J, Hill Meyers B, Armstrong SA, Anderson KC, Stegmaier K, Reich M, Pellman D, Boehm JS, Mesirov JP, Golub TR, Root DE, Hahn WC. Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies. Sci Data. 2014; 1:140035. PMID: 25984343; PMCID: PMC4432652.
  11. Varetti G, Pellman D, Gordon DJ. Aurea mediocritas: the importance of a balanced genome. Cold Spring Harb Perspect Biol. 2014 Sep 18; 6(11):a015842. PMID: 25237130.
    View in: PubMed
  12. Godinho SA, Pellman D. Causes and consequences of centrosome abnormalities in cancer. Philos Trans R Soc Lond B Biol Sci. 2014 Sep 05; 369(1650). PMID: 25047621; PMCID: PMC4113111.
  13. Ganem NJ, Cornils H, Chiu SY, O'Rourke KP, Arnaud J, Yimlamai D, Théry M, Camargo FD, Pellman D. Cytokinesis failure triggers hippo tumor suppressor pathway activation. Cell. 2014 Aug 14; 158(4):833-48. PMID: 25126788; PMCID: PMC4136486.
  14. Lane AA, Chapuy B, Lin CY, Tivey T, Li H, Townsend EC, van Bodegom D, Day TA, Wu SC, Liu H, Yoda A, Alexe G, Schinzel AC, Sullivan TJ, Malinge S, Taylor JE, Stegmaier K, Jaffe JD, Bustin M, te Kronnie G, Izraeli S, Harris MH, Stevenson KE, Neuberg D, Silverman LB, Sallan SE, Bradner JE, Hahn WC, Crispino JD, Pellman D, Weinstock DM. Triplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation. Nat Genet. 2014 Jun; 46(6):618-23. PMID: 24747640; PMCID: PMC4040006.
  15. Godinho SA, Picone R, Burute M, Dagher R, Su Y, Leung CT, Polyak K, Brugge JS, Théry M, Pellman D. Oncogene-like induction of cellular invasion from centrosome amplification. Nature. 2014 Jun 05; 510(7503):167-71. PMID: 24739973; PMCID: PMC4061398.
  16. Lee DH, Acharya SS, Kwon M, Drane P, Guan Y, Adelmant G, Kalev P, Shah J, Pellman D, Marto JA, Chowdhury D. Dephosphorylation enables the recruitment of 53BP1 to double-strand DNA breaks. Mol Cell. 2014 May 08; 54(3):512-25. PMID: 24703952; PMCID: PMC4030556.
  17. Zhang CZ, Leibowitz ML, Pellman D. Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements. Genes Dev. 2013 Dec 01; 27(23):2513-30. PMID: 24298051; PMCID: PMC3861665.
  18. Atkins BD, Yoshida S, Saito K, Wu CF, Lew DJ, Pellman D. Inhibition of Cdc42 during mitotic exit is required for cytokinesis. J Cell Biol. 2013 Jul 22; 202(2):231-40. PMID: 23878274; PMCID: PMC3718968.
  19. Su X, Arellano-Santoyo H, Portran D, Gaillard J, Vantard M, Thery M, Pellman D. Microtubule-sliding activity of a kinesin-8 promotes spindle assembly and spindle-length control. Nat Cell Biol. 2013 Aug; 15(8):948-57. PMID: 23851487; PMCID: PMC3767134.
  20. Ganem NJ, Pellman D. Linking abnormal mitosis to the acquisition of DNA damage. J Cell Biol. 2012 Dec 10; 199(6):871-81. PMID: 23229895; PMCID: PMC3518222.
  21. Su X, Ohi R, Pellman D. Move in for the kill: motile microtubule regulators. Trends Cell Biol. 2012 Nov; 22(11):567-75. PMID: 22959403; PMCID: PMC3482944.
  22. Buttery SM, Kono K, Stokasimov E, Pellman D. Regulation of the formin Bnr1 by septins anda MARK/Par1-family septin-associated kinase. Mol Biol Cell. 2012 Oct; 23(20):4041-53. PMID: 22918953; PMCID: PMC3469519.
  23. Kono K, Saeki Y, Yoshida S, Tanaka K, Pellman D. Proteasomal degradation resolves competition between cell polarization and cellular wound healing. Cell. 2012 Jul 06; 150(1):151-64. PMID: 22727045.
    View in: PubMed
  24. Varetti G, Pellman D. "Two" much of a good thing: telomere damage-induced genome doubling drives tumorigenesis. Cancer Cell. 2012 Jun 12; 21(6):712-4. PMID: 22698395.
    View in: PubMed
  25. Carter SL, Cibulskis K, Helman E, McKenna A, Shen H, Zack T, Laird PW, Onofrio RC, Winckler W, Weir BA, Beroukhim R, Pellman D, Levine DA, Lander ES, Meyerson M, Getz G. Absolute quantification of somatic DNA alterations in human cancer. Nat Biotechnol. 2012 May; 30(5):413-21. PMID: 22544022; PMCID: PMC4383288.
  26. Gordon DJ, Resio B, Pellman D. Causes and consequences of aneuploidy in cancer. Nat Rev Genet. 2012 Jan 24; 13(3):189-203. PMID: 22269907.
    View in: PubMed
  27. Crasta K, Ganem NJ, Dagher R, Lantermann AB, Ivanova EV, Pan Y, Nezi L, Protopopov A, Chowdhury D, Pellman D. DNA breaks and chromosome pulverization from errors in mitosis. Nature. 2012 Jan 18; 482(7383):53-8. PMID: 22258507; PMCID: PMC3271137.
  28. Su X, Qiu W, Gupta ML, Pereira-Leal JB, Reck-Peterson SL, Pellman D. Mechanisms underlying the dual-mode regulation of microtubule dynamics by Kip3/kinesin-8. Mol Cell. 2011 Sep 02; 43(5):751-63. PMID: 21884976; PMCID: PMC3181003.
  29. Bettencourt-Dias M, Hildebrandt F, Pellman D, Woods G, Godinho SA. Centrosomes and cilia in human disease. Trends Genet. 2011 Aug; 27(8):307-15. PMID: 21680046; PMCID: PMC3144269.
  30. Storchová Z, Becker JS, Talarek N, Kögelsberger S, Pellman D. Bub1, Sgo1, and Mps1 mediate a distinct pathway for chromosome biorientation in budding yeast. Mol Biol Cell. 2011 May; 22(9):1473-85. PMID: 21389114; PMCID: PMC3084670.
  31. Meyerson M, Pellman D. Cancer genomes evolve by pulverizing single chromosomes. Cell. 2011 Jan 07; 144(1):9-10. PMID: 21215363.
    View in: PubMed
  32. Breuer M, Kolano A, Kwon M, Li CC, Tsai TF, Pellman D, Brunet S, Verlhac MH. HURP permits MTOC sorting for robust meiotic spindle bipolarity, similar to extra centrosome clustering in cancer cells. J Cell Biol. 2010 Dec 27; 191(7):1251-60. PMID: 21173113; PMCID: PMC3010075.
  33. Vinciguerra P, Godinho SA, Parmar K, Pellman D, D'Andrea AD. Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells. J Clin Invest. 2010 Nov; 120(11):3834-42. PMID: 20921626; PMCID: PMC2964984.
  34. Pellman D. David Pellman: Grasping the geometry of cancer. Interviewed by Caitlin Sedwick. J Cell Biol. 2010 Jul 12; 190(1):4-5. PMID: 20624895; PMCID: PMC2911666.
  35. Kwiatkowski N, Jelluma N, Filippakopoulos P, Soundararajan M, Manak MS, Kwon M, Choi HG, Sim T, Deveraux QL, Rottmann S, Pellman D, Shah JV, Kops GJ, Knapp S, Gray NS. Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat Chem Biol. 2010 May; 6(5):359-68. PMID: 20383151; PMCID: PMC2857554.
  36. Tischfield MA, Baris HN, Wu C, Rudolph G, Van Maldergem L, He W, Chan WM, Andrews C, Demer JL, Robertson RL, Mackey DA, Ruddle JB, Bird TD, Gottlob I, Pieh C, Traboulsi EI, Pomeroy SL, Hunter DG, Soul JS, Newlin A, Sabol LJ, Doherty EJ, de Uzcátegui CE, de Uzcátegui N, Collins ML, Sener EC, Wabbels B, Hellebrand H, Meitinger T, de Berardinis T, Magli A, Schiavi C, Pastore-Trossello M, Koc F, Wong AM, Levin AV, Geraghty MT, Descartes M, Flaherty M, Jamieson RV, Møller HU, Meuthen I, Callen DF, Kerwin J, Lindsay S, Meindl A, Gupta ML, Pellman D, Engle EC. Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance. Cell. 2010 Jan 08; 140(1):74-87. PMID: 20074521; PMCID: PMC3164117.
  37. Rhodes J, Amsterdam A, Sanda T, Moreau LA, McKenna K, Heinrichs S, Ganem NJ, Ho KW, Neuberg DS, Johnston A, Ahn Y, Kutok JL, Hromas R, Wray J, Lee C, Murphy C, Radtke I, Downing JR, Fleming MD, MacConaill LE, Amatruda JF, Gutierrez A, Galinsky I, Stone RM, Ross EA, Pellman DS, Kanki JP, Look AT. Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression. Mol Cell Biol. 2009 Nov; 29(21):5911-22. PMID: 19704007; PMCID: PMC2772726.
  38. Ganem NJ, Godinho SA, Pellman D. A mechanism linking extra centrosomes to chromosomal instability. Nature. 2009 Jul 09; 460(7252):278-82. PMID: 19506557; PMCID: PMC2743290.
  39. Godinho SA, Kwon M, Pellman D. Centrosomes and cancer: how cancer cells divide with too many centrosomes. Cancer Metastasis Rev. 2009 Jun; 28(1-2):85-98. PMID: 19156503.
    View in: PubMed
  40. Yoshida S, Bartolini S, Pellman D. Mechanisms for concentrating Rho1 during cytokinesis. Genes Dev. 2009 Apr 01; 23(7):810-23. PMID: 19339687; PMCID: PMC2666341.
  41. Chandhok NS, Pellman D. A little CIN may cost a lot: revisiting aneuploidy and cancer. Curr Opin Genet Dev. 2009 Feb; 19(1):74-81. PMID: 19195877.
    View in: PubMed
  42. Atkins BD, Yoshida S, Pellman D. Symmetry breaking: scaffold plays matchmaker for polarity signaling proteins. Curr Biol. 2008 Dec 23; 18(24):R1130-2. PMID: 19108767.
    View in: PubMed
  43. Kwon M, Godinho SA, Chandhok NS, Ganem NJ, Azioune A, Thery M, Pellman D. Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes. Genes Dev. 2008 Aug 15; 22(16):2189-203. PMID: 18662975; PMCID: PMC2518815.
  44. Austin KM, Gupta ML, Coats SA, Tulpule A, Mostoslavsky G, Balazs AB, Mulligan RC, Daley G, Pellman D, Shimamura A. Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome. J Clin Invest. 2008 Apr; 118(4):1511-8. PMID: 18324336; PMCID: PMC2263145.
  45. Kono K, Nogami S, Abe M, Nishizawa M, Morishita S, Pellman D, Ohya Y. G1/S cyclin-dependent kinase regulates small GTPase Rho1p through phosphorylation of RhoGEF Tus1p in Saccharomyces cerevisiae. Mol Biol Cell. 2008 Apr; 19(4):1763-71. PMID: 18256282; PMCID: PMC2291405.
  46. Yoshida S, Pellman D. Plugging the GAP between cell polarity and cell cycle. EMBO Rep. 2008 Jan; 9(1):39-41. PMID: 18174895; PMCID: PMC2246625.
  47. Ganem NJ, Pellman D. Limiting the proliferation of polyploid cells. Cell. 2007 Nov 02; 131(3):437-40. PMID: 17981108.
    View in: PubMed
  48. Ceol CJ, Pellman D, Zon LI. APC and colon cancer: two hits for one. Nat Med. 2007 Nov; 13(11):1286-7. PMID: 17987022.
    View in: PubMed
  49. Schüller U, Zhao Q, Godinho SA, Heine VM, Medema RH, Pellman D, Rowitch DH. Forkhead transcription factor FoxM1 regulates mitotic entry and prevents spindle defects in cerebellar granule neuron precursors. Mol Cell Biol. 2007 Dec; 27(23):8259-70. PMID: 17893320; PMCID: PMC2169184.
  50. Jallepalli PV, Pellman D. Cell biology. Aneuploidy in the balance. Science. 2007 Aug 17; 317(5840):904-5. PMID: 17702931.
    View in: PubMed
  51. Buttery SM, Yoshida S, Pellman D. Yeast formins Bni1 and Bnr1 utilize different modes of cortical interaction during the assembly of actin cables. Mol Biol Cell. 2007 May; 18(5):1826-38. PMID: 17344480; PMCID: PMC1855024.
  52. Pellman D. Cell biology: aneuploidy and cancer. Nature. 2007 Mar 01; 446(7131):38-9. PMID: 17330036.
    View in: PubMed
  53. Ganem NJ, Storchova Z, Pellman D. Tetraploidy, aneuploidy and cancer. Curr Opin Genet Dev. 2007 Apr; 17(2):157-62. PMID: 17324569.
    View in: PubMed
  54. Storchová Z, Breneman A, Cande J, Dunn J, Burbank K, O'Toole E, Pellman D. Genome-wide genetic analysis of polyploidy in yeast. Nature. 2006 Oct 05; 443(7111):541-7. PMID: 17024086.
    View in: PubMed
  55. Gupta ML, Carvalho P, Roof DM, Pellman D. Plus end-specific depolymerase activity of Kip3, a kinesin-8 protein, explains its role in positioning the yeast mitotic spindle. Nat Cell Biol. 2006 Sep; 8(9):913-23. PMID: 16906148.
    View in: PubMed
  56. Yoshida S, Kono K, Lowery DM, Bartolini S, Yaffe MB, Ohya Y, Pellman D. Polo-like kinase Cdc5 controls the local activation of Rho1 to promote cytokinesis. Science. 2006 Jul 07; 313(5783):108-11. PMID: 16763112.
    View in: PubMed
  57. Fujiwara T, Bandi M, Nitta M, Ivanova EV, Bronson RT, Pellman D. Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature. 2005 Oct 13; 437(7061):1043-7. PMID: 16222300.
    View in: PubMed
  58. Yoshida S, Guillet M, Pellman D. MEN signaling: daughter bound pole must escape her mother to be fully active. Dev Cell. 2005 Aug; 9(2):168-70. PMID: 16054023.
    View in: PubMed
  59. Carvalho P, Pellman D. Mitotic spindle: laser microsurgery in yeast cells. Curr Biol. 2004 Sep 21; 14(18):R748-50. PMID: 15380083.
    View in: PubMed
  60. Andalis AA, Storchova Z, Styles C, Galitski T, Pellman D, Fink GR. Defects arising from whole-genome duplications in Saccharomyces cerevisiae. Genetics. 2004 Jul; 167(3):1109-21. PMID: 15280227; PMCID: PMC1470947.
  61. Carvalho P, Gupta ML, Hoyt MA, Pellman D. Cell cycle control of kinesin-mediated transport of Bik1 (CLIP-170) regulates microtubule stability and dynein activation. Dev Cell. 2004 Jun; 6(6):815-29. PMID: 15177030.
    View in: PubMed
  62. Xu Y, Moseley JB, Sagot I, Poy F, Pellman D, Goode BL, Eck MJ. Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture. Cell. 2004 Mar 05; 116(5):711-23. PMID: 15006353.
    View in: PubMed
  63. Molk JN, Schuyler SC, Liu JY, Evans JG, Salmon ED, Pellman D, Bloom K. The differential roles of budding yeast Tem1p, Cdc15p, and Bub2p protein dynamics in mitotic exit. Mol Biol Cell. 2004 Apr; 15(4):1519-32. PMID: 14718561; PMCID: PMC379252.
  64. Storchova Z, Pellman D. From polyploidy to aneuploidy, genome instability and cancer. Nat Rev Mol Cell Biol. 2004 Jan; 5(1):45-54. PMID: 14708009.
    View in: PubMed
  65. Moseley JB, Sagot I, Manning AL, Xu Y, Eck MJ, Pellman D, Goode BL. A conserved mechanism for Bni1- and mDia1-induced actin assembly and dual regulation of Bni1 by Bud6 and profilin. Mol Biol Cell. 2004 Feb; 15(2):896-907. PMID: 14657240; PMCID: PMC329402.
  66. Carvalho P, Tirnauer JS, Pellman D. Surfing on microtubule ends. Trends Cell Biol. 2003 May; 13(5):229-37. PMID: 12742166.
    View in: PubMed
  67. Chestukhin A, Pfeffer C, Milligan S, DeCaprio JA, Pellman D. Processing, localization, and requirement of human separase for normal anaphase progression. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4574-9. PMID: 12672959; PMCID: PMC153597.
  68. Sheeman B, Carvalho P, Sagot I, Geiser J, Kho D, Hoyt MA, Pellman D. Determinants of S. cerevisiae dynein localization and activation: implications for the mechanism of spindle positioning. Curr Biol. 2003 Mar 04; 13(5):364-72. PMID: 12620184.
    View in: PubMed
  69. Schuyler SC, Liu JY, Pellman D. The molecular function of Ase1p: evidence for a MAP-dependent midzone-specific spindle matrix. Microtubule-associated proteins. J Cell Biol. 2003 Feb 17; 160(4):517-28. PMID: 12591913; PMCID: PMC2173742.
  70. Leader B, Lim H, Carabatsos MJ, Harrington A, Ecsedy J, Pellman D, Maas R, Leder P. Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes. Nat Cell Biol. 2002 Dec; 4(12):921-8. PMID: 12447394.
    View in: PubMed
  71. Sagot I, Rodal AA, Moseley J, Goode BL, Pellman D. An actin nucleation mechanism mediated by Bni1 and profilin. Nat Cell Biol. 2002 Aug; 4(8):626-31. PMID: 12134165.
    View in: PubMed
  72. Schuyler SC, Pellman D. Analysis of the size and shape of protein complexes from yeast. Methods Enzymol. 2002; 351:150-68. PMID: 12073341.
    View in: PubMed
  73. Sagot I, Klee SK, Pellman D. Yeast formins regulate cell polarity by controlling the assembly of actin cables. Nat Cell Biol. 2002 Jan; 4(1):42-50. PMID: 11740491.
    View in: PubMed
  74. Lin H, de Carvalho P, Kho D, Tai CY, Pierre P, Fink GR, Pellman D. Polyploids require Bik1 for kinetochore-microtubule attachment. J Cell Biol. 2001 Dec 24; 155(7):1173-84. PMID: 11756471; PMCID: PMC2199317.
  75. Yarm F, Sagot I, Pellman D. The social life of actin and microtubules: interaction versus cooperation. Curr Opin Microbiol. 2001 Dec; 4(6):696-702. PMID: 11731322.
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  76. Lechler T, Jonsdottir GA, Klee SK, Pellman D, Li R. A two-tiered mechanism by which Cdc42 controls the localization and activation of an Arp2/3-activating motor complex in yeast. J Cell Biol. 2001 Oct 15; 155(2):261-70. PMID: 11604421; PMCID: PMC2198833.
  77. Pellman D, Christman MF. Separase anxiety: dissolving the sister bond and more. Nat Cell Biol. 2001 Sep; 3(9):E207-9. PMID: 11533673.
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  78. Huang JN, Park I, Ellingson E, Littlepage LE, Pellman D. Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p. J Cell Biol. 2001 Jul 09; 154(1):85-94. PMID: 11448992; PMCID: PMC2196868.
  79. Schuyler SC, Pellman D. Microtubule "plus-end-tracking proteins": The end is just the beginning. Cell. 2001 May 18; 105(4):421-4. PMID: 11371339.
    View in: PubMed
  80. Pellman D. Cancer. A CINtillating new job for the APC tumor suppressor. Science. 2001 Mar 30; 291(5513):2555-6. PMID: 11286276.
    View in: PubMed
  81. Jónsson ZO, Dhar SK, Narlikar GJ, Auty R, Wagle N, Pellman D, Pratt RE, Kingston R, Dutta A. Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J Biol Chem. 2001 May 11; 276(19):16279-88. PMID: 11278922.
    View in: PubMed
  82. Schuyler SC, Pellman D. Search, capture and signal: games microtubules and centrosomes play. J Cell Sci. 2001 Jan; 114(Pt 2):247-55. PMID: 11148127.
    View in: PubMed
  83. Lee L, Tirnauer JS, Li J, Schuyler SC, Liu JY, Pellman D. Positioning of the mitotic spindle by a cortical-microtubule capture mechanism. Science. 2000 Mar 24; 287(5461):2260-2. PMID: 10731147.
    View in: PubMed
  84. Tirnauer JS, O'Toole E, Berrueta L, Bierer BE, Pellman D. Yeast Bim1p promotes the G1-specific dynamics of microtubules. J Cell Biol. 1999 May 31; 145(5):993-1007. PMID: 10352017; PMCID: PMC2133138.
  85. Berrueta L, Tirnauer JS, Schuyler SC, Pellman D, Bierer BE. The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain. Curr Biol. 1999 Apr 22; 9(8):425-8. PMID: 10226031.
    View in: PubMed
  86. Lee L, Klee SK, Evangelista M, Boone C, Pellman D. Control of mitotic spindle position by the Saccharomyces cerevisiae formin Bni1p. J Cell Biol. 1999 Mar 08; 144(5):947-61. PMID: 10085293; PMCID: PMC2148193.
  87. Berrueta L, Kraeft SK, Tirnauer JS, Schuyler SC, Chen LB, Hill DE, Pellman D, Bierer BE. The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules. Proc Natl Acad Sci U S A. 1998 Sep 01; 95(18):10596-601. PMID: 9724749; PMCID: PMC27940.
  88. D'Andrea A, Pellman D. Deubiquitinating enzymes: a new class of biological regulators. Crit Rev Biochem Mol Biol. 1998; 33(5):337-52. PMID: 9827704.
    View in: PubMed
  89. DeZwaan TM, Ellingson E, Pellman D, Roof DM. Kinesin-related KIP3 of Saccharomyces cerevisiae is required for a distinct step in nuclear migration. J Cell Biol. 1997 Sep 08; 138(5):1023-40. PMID: 9281581; PMCID: PMC2136764.
  90. Juang YL, Huang J, Peters JM, McLaughlin ME, Tai CY, Pellman D. APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science. 1997 Feb 28; 275(5304):1311-4. PMID: 9036857.
    View in: PubMed
  91. Pellman D, Bagget M, Tu YH, Fink GR, Tu H. Two microtubule-associated proteins required for anaphase spindle movement in Saccharomyces cerevisiae. J Cell Biol. 1995 Sep; 130(6):1373-85. PMID: 7559759; PMCID: PMC2120566.
  92. Loeb JD, Schlenstedt G, Pellman D, Kornitzer D, Silver PA, Fink GR. The yeast nuclear import receptor is required for mitosis. Proc Natl Acad Sci U S A. 1995 Aug 15; 92(17):7647-51. PMID: 7644471; PMCID: PMC41202.
  93. Pellman D, McLaughlin ME, Fink GR. TATA-dependent and TATA-independent transcription at the HIS4 gene of yeast. Nature. 1990 Nov 01; 348(6296):82-5. PMID: 2234066.
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  94. Stoeckle MY, Sugano S, Hampe A, Vashistha A, Pellman D, Hanafusa H. 78-kilodalton glucose-regulated protein is induced in Rous sarcoma virus-transformed cells independently of glucose deprivation. Mol Cell Biol. 1988 Jul; 8(7):2675-80. PMID: 2841586; PMCID: PMC363477.
  95. Pellman D, Garber EA, Cross FR, Hanafusa H. Fine structural mapping of a critical NH2-terminal region of p60src. Proc Natl Acad Sci U S A. 1985 Mar; 82(6):1623-7. PMID: 2984663; PMCID: PMC397324.
  96. Pellman D, Garber EA, Cross FR, Hanafusa H. An N-terminal peptide from p60src can direct myristylation and plasma membrane localization when fused to heterologous proteins. Nature. 1985 Mar 28-Apr 3; 314(6009):374-7. PMID: 3920530.
    View in: PubMed
  97. Cross FR, Garber EA, Pellman D, Hanafusa H. A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation. Mol Cell Biol. 1984 Sep; 4(9):1834-42. PMID: 6092942; PMCID: PMC368993.
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