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Yeguang Hu, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Cao Y, Yisimayi A, Jian F, Song W, Xiao T, Wang L, Du S, Wang J, Li Q, Chen X, Yu Y, Wang P, Zhang Z, Liu P, An R, Hao X, Wang Y, Wang J, Feng R, Sun H, Zhao L, Zhang W, Zhao D, Zheng J, Yu L, Li C, Zhang N, Wang R, Niu X, Yang S, Song X, Chai Y, Hu Y, Shi Y, Zheng L, Li Z, Gu Q, Shao F, Huang W, Jin R, Shen Z, Wang Y, Wang X, Xiao J, Xie XS. BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection. Nature. 2022 08; 608(7923):593-602. PMID: 35714668; PMCID: PMC9385493.
    Citations: 15     Fields:    
  2. Tong J, Li H, Hu Y, Zhao Z, Li M. TMEM158 Regulates the Canonical and Non-Canonical Pathways of TGF-ß to Mediate EMT in Triple-Negative Breast Cancer. J Cancer. 2022; 13(8):2694-2704. PMID: 35711843; PMCID: PMC9174849.
    Citations:    
  3. Chu Z, Gu L, Hu Y, Zhang X, Li M, Chen J, Teng D, Huang M, Shen CH, Cai L, Yoshida T, Qi Y, Niu Z, Feng A, Geng S, Frederick DT, Specht E, Piris A, Sullivan RJ, Flaherty KT, Boland GM, Georgopoulos K, Liu D, Shi Y, Zheng B. STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming. Nat Commun. 2022 04 06; 13(1):1859. PMID: 35388001; PMCID: PMC8986786.
    Citations: 1     Fields:    Translation:Humans
  4. Wang K, Hu Y, Xu L, Zhao S, Song C, Sun S, Li X, Li M. A novel mutant PIK3R1EY451delinsD breast cancer patient resistant to HER2-targeted therapy treated with everolimus: a case report. Mol Biol Rep. 2022 Jul; 49(7):6155-6160. PMID: 35384625.
    Citations:    Fields:    Translation:Humans
  5. Tong J, Tan D, Ma J, Hu Y, Li M. Nomogram to predict contralateral breast cancer risk in breast cancer survivors: A SEER-based study. Medicine (Baltimore). 2021 Nov 19; 100(46):e27595. PMID: 34797281; PMCID: PMC8601336.
    Citations:    Fields:    Translation:Humans
  6. Zhang S, Dai H, Li W, Wang R, Wu H, Shen M, Hu Y, Xie L, Xing Y. TMEM116 is required for lung cancer cell motility and metastasis through PDK1 signaling pathway. Cell Death Dis. 2021 11 16; 12(12):1086. PMID: 34789718; PMCID: PMC8599864.
    Citations:    Fields:    Translation:HumansAnimalsCells
  7. Yang H, Hu Y, Weng M, Liu X, Wan P, Hu Y, Ma M, Zhang Y, Xia H, Lv K. Hypoxia inducible lncRNA-CBSLR modulates ferroptosis through m6A-YTHDF2-dependent modulation of CBS in gastric cancer. J Adv Res. 2022 03; 37:91-106. PMID: 35499052; PMCID: PMC9039740.
    Citations: 1     Fields:    Translation:Humans
  8. Hu Y, Wang M, Wang K, Gao J, Tong J, Zhao Z, Li M. A potential role for metastasis-associated in colon cancer 1 (MACC1) as a pan-cancer prognostic and immunological biomarker. Math Biosci Eng. 2021 09 23; 18(6):8331-8353. PMID: 34814302.
    Citations:    Fields:    Translation:Humans
  9. Hu Y, Wang X, Song J, Wu J, Xu J, Chai Y, Ding Y, Wang B, Wang C, Zhao Y, Shen Z, Xu X, Cao X. Chromatin remodeler ARID1A binds IRF3 to selectively induce antiviral interferon production in macrophages. Cell Death Dis. 2021 07 27; 12(8):743. PMID: 34315861; PMCID: PMC8316351.
    Citations:    Fields:    Translation:HumansAnimalsCells
  10. Hu Y, Gao J, Wang M, Li M. Potential Prospect of CDK4/6 Inhibitors in Triple-Negative Breast Cancer. Cancer Manag Res. 2021; 13:5223-5237. PMID: 34234565; PMCID: PMC8257068.
    Citations: 8     
  11. Huo Q, He X, Li Z, Yang F, He S, Shao L, Hu Y, Chen S, Xie N. SCUBE3 serves as an independent poor prognostic factor in breast cancer. Cancer Cell Int. 2021 May 18; 21(1):268. PMID: 34006286.
    Citations:    
  12. Xu X, Xu J, Wu J, Hu Y, Han Y, Gu Y, Zhao K, Zhang Q, Liu X, Liu J, Liu B, Cao X. Phosphorylation-Mediated IFN-?R2 Membrane Translocation Is Required to Activate Macrophage Innate Response. Cell. 2021 Mar 04; 184(5):1393-1394. PMID: 33667370.
    Citations: 1     Fields:    
  13. Zhu X, Tian X, Ji L, Zhang X, Cao Y, Shen C, Hu Y, Wong JWH, Fang JY, Hong J, Chen H. A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patients. NPJ Precis Oncol. 2021 Feb 12; 5(1):7. PMID: 33580207.
    Citations: 8     
  14. Chen L, Guo X, Hu Y, Li L, Liang G, Zhang G. Epigallocatechin-3-gallate sensitises multidrug-resistant oral carcinoma xenografts to vincristine sulfate. FEBS Open Bio. 2020 07; 10(7):1403-1413. PMID: 32475087.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  15. Cheng N, Liu Y, Zhao G, Xu Y, Zhang T, Chen Y, Yan G, Hu Y, Yao S, Wang Z, Wang C, Chen Z, Hu Z, Liu D, Chen T. Phase I Trial of Intensity-Modulated Hyperfractionated Radiotherapy Boost with Concurrent Chemotherapy Immediately Following Standard Chemoradiotherapy in Patients Primarily with Advanced Intra-thoracic/Cervical Esophageal Squamous Cell Carcinomas. Int J Radiat Oncol Biol Phys. 2020 02 01; 106(2):340-348. PMID: 31655197.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  16. Yu CY, Han JX, Zhang J, Jiang P, Shen C, Guo F, Tang J, Yan T, Tian X, Zhu X, Ma D, Hu Y, Xie Y, Du W, Zhong M, Chen J, Liu Q, Sun D, Chen Y, Zou W, Hong J, Chen H, Fang JY. A 16q22.1 variant confers susceptibility to colorectal cancer as a distal regulator of ZFP90. Oncogene. 2020 02; 39(6):1347-1360. PMID: 31641208.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  17. Yoshida T, Hu Y, Zhang Z, Emmanuel AO, Galani K, Muhire B, Snippert HJ, Williams CJ, Tolstorukov MY, Gounari F, Georgopoulos K. Chromatin restriction by the nucleosome remodeler Mi-2ß and functional interplay with lineage-specific transcription regulators control B-cell differentiation. Genes Dev. 2019 07 01; 33(13-14):763-781. PMID: 31123064; PMCID: PMC6601517.
    Citations: 11     Fields:    Translation:AnimalsCells
  18. Hu Y, Huang Y, Wang Z, Wang Y, Ye X, Wong W, Li C, Sun D. Gold/WS2 nanocomposites fabricated by in-situ ultrasonication and assembling for photoelectrochemical immunosensing of carcinoembryonic antigen. Mikrochim Acta. 2018 12 01; 185(12):570. PMID: 30506429.
    Citations: 2     Fields:    Translation:Cells
  19. Xu X, Xu J, Wu J, Hu Y, Han Y, Gu Y, Zhao K, Zhang Q, Liu X, Liu J, Liu B, Cao X. Phosphorylation-Mediated IFN-?R2 Membrane Translocation Is Required to Activate Macrophage Innate Response. Cell. 2018 11 15; 175(5):1336-1351.e17. PMID: 30318148.
    Citations: 11     Fields:    Translation:AnimalsCells
  20. Liu Y, Zhao G, Xu Y, Zhang T, Chen Z, Yan G, Tu W, Hu Y, Chen Y, He X, Li X, Chen H, Yao S, Hu Z, Chen X, Chen T. Phase II Study of Adjuvant Chemoradiotherapy Using Docetaxel/Cisplatin/5-Fluorouracil Before and After Intensity-modulated Radiotherapy With Concurrent Docetaxel in Patients With Completely (R0) Resected Gastric Carcinoma. Am J Clin Oncol. 2018 07; 41(7):619-625. PMID: 28263232; PMCID: PMC6023597.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  21. Hu Y, Huang Y, Wang Y, Li C, Wong W, Ye X, Sun D. A photoelectrochemical immunosensor based on gold nanoparticles/ZnAgInS quaternary quantum dots for the high-performance determination of hepatitis B virus surface antigen. Anal Chim Acta. 2018 Dec 04; 1035:136-145. PMID: 30224131.
    Citations: 6     Fields:    Translation:HumansCells
  22. Liang L, Wang H, Shi H, Li Z, Yao H, Bu Z, Song N, Li C, Xiang D, Zhang Y, Wang J, Hu Y, Xu Q, Ma Y, Cheng Z, Wang Y, Zhao S, Qian J, Chen Y, Fang JY, Xu J. A Designed Peptide Targets Two Types of Modifications of p53 with Anti-cancer Activity. Cell Chem Biol. 2018 06 21; 25(6):761-774.e5. PMID: 29681526.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  23. Tian X, Zhu X, Yan T, Yu C, Shen C, Hu Y, Hong J, Chen H, Fang JY. Recurrence-associated gene signature optimizes recurrence-free survival prediction of colorectal cancer. Mol Oncol. 2017 11; 11(11):1544-1560. PMID: 28796930.
    Citations: 27     Fields:    Translation:Humans
  24. Xu J, Xu X, Wang B, Ma Y, Zhang L, Xu H, Hu Y, Wu J, Cao X. Nuclear carbonic anhydrase 6B associates with PRMT5 to epigenetically promote IL-12 expression in innate response. Proc Natl Acad Sci U S A. 2017 08 08; 114(32):8620-8625. PMID: 28739930; PMCID: PMC5559001.
    Citations: 10     Fields:    Translation:AnimalsCells
  25. Hu Y, Yoshida T, Georgopoulos K. Transcriptional circuits in B cell transformation. Curr Opin Hematol. 2017 Jul; 24(4):345-352. PMID: 28463873; PMCID: PMC5701664.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  26. Qian J, Li Y, Yao H, Tian H, Wang H, Ai L, Xie Y, Bao Y, Liang L, Hu Y, Zhang Y, Wang J, Li C, Tang J, Chen Y, Xu J, Fang JY. ASAP3 regulates microvilli structure in parietal cells and presents intervention target for gastric acidity. Signal Transduct Target Ther. 2017; 2:17003. PMID: 29263912.
    Citations:    Fields:    
  27. Hu Y, Zhang Z, Kashiwagi M, Yoshida T, Joshi I, Jena N, Somasundaram R, Emmanuel AO, Sigvardsson M, Fitamant J, El-Bardeesy N, Gounari F, Van Etten RA, Georgopoulos K. Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia. Genes Dev. 2016 09 01; 30(17):1971-90. PMID: 27664237; PMCID: PMC5066240.
    Citations: 32     Fields:    Translation:AnimalsCells
  28. Sun TT, He J, Liang Q, Ren LL, Yan TT, Yu TC, Tang JY, Bao YJ, Hu Y, Lin Y, Sun D, Chen YX, Hong J, Chen H, Zou W, Fang JY. LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification Pattern. Cancer Discov. 2016 07; 6(7):784-801. PMID: 27147598.
    Citations: 176     Fields:    Translation:HumansAnimalsCells
  29. Zhang Y, Hu Y, Fang JY, Xu J. Gain-of-function miRNA signature by mutant p53 associates with poor cancer outcome. Oncotarget. 2016 Mar 08; 7(10):11056-66. PMID: 26840456.
    Citations: 16     Fields:    Translation:HumansCells
  30. Chen J, Li Y, Hao H, Li C, Du Y, Hu Y, Li J, Liang Z, Li C, Liu J, Chen L. Mesenchymal Stem Cell Conditioned Medium Promotes Proliferation and Migration of Alveolar Epithelial Cells under Septic Conditions In Vitro via the JNK-P38 Signaling Pathway. Cell Physiol Biochem. 2015; 37(5):1830-46. PMID: 26584283.
    Citations: 17     Fields:    Translation:HumansCells
  31. Wang J, Liu G, Xu Z, Dai J, Song P, Shi J, Hu Y, Hu Z, Nie G, Chang YZ, Zhao Y. Hepcidin levels in hyperprolactinemic women monitored by nanopore thin film based assay: correlation with pregnancy-associated hormone prolactin. Nanomedicine. 2015 May; 11(4):871-8. PMID: 25659646.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  32. Hu Y, Wang J, Qian J, Kong X, Tang J, Wang Y, Chen H, Hong J, Zou W, Chen Y, Xu J, Fang JY. Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancer. Cancer Res. 2014 Dec 01; 74(23):6890-902. PMID: 25277524.
    Citations: 144     Fields:    Translation:HumansCells
  33. Wang J, Qian J, Hu Y, Kong X, Chen H, Shi Q, Jiang L, Wu C, Zou W, Chen Y, Xu J, Fang JY. ArhGAP30 promotes p53 acetylation and function in colorectal cancer. Nat Commun. 2014 Aug 26; 5:4735. PMID: 25156493.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  34. Hu Y, Chen HY, Yu CY, Xu J, Wang JL, Qian J, Zhang X, Fang JY. A long non-coding RNA signature to improve prognosis prediction of colorectal cancer. Oncotarget. 2014 Apr 30; 5(8):2230-42. PMID: 24809982; PMCID: PMC4039159.
    Citations: 108     Fields:    Translation:HumansCells
  35. Qian J, Kong X, Deng N, Tan P, Chen H, Wang J, Li Z, Hu Y, Zou W, Xu J, Fang JY. OCT1 is a determinant of synbindin-related ERK signalling with independent prognostic significance in gastric cancer. Gut. 2015 Jan; 64(1):37-48. PMID: 24717932; PMCID: PMC4283676.
    Citations: 35     Fields:    Translation:AnimalsCells
  36. Xu J, Qian J, Hu Y, Wang J, Zhou X, Chen H, Fang JY. Heterogeneity of Li-Fraumeni syndrome links to unequal gain-of-function effects of p53 mutations. Sci Rep. 2014 Feb 27; 4:4223. PMID: 24573247.
    Citations: 37     Fields:    Translation:Humans
  37. Xu J, Zhou X, Wang J, Li Z, Kong X, Qian J, Hu Y, Fang JY. RhoGAPs attenuate cell proliferation by direct interaction with p53 tetramerization domain. Cell Rep. 2013 May 30; 3(5):1526-38. PMID: 23684608.
    Citations: 27     Fields:    Translation:HumansCells
  38. Xu Y, Xu C, Kato A, Tempel W, Abreu JG, Bian C, Hu Y, Hu D, Zhao B, Cerovina T, Diao J, Wu F, He HH, Cui Q, Clark E, Ma C, Barbara A, Veenstra GJ, Xu G, Kaiser UB, Liu XS, Sugrue SP, He X, Min J, Kato Y, Shi YG. Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development. Cell. 2012 Dec 07; 151(6):1200-13. PMID: 23217707.
    Citations: 118     Fields:    Translation:AnimalsCells
  39. Lian CG, Xu Y, Ceol C, Wu F, Larson A, Dresser K, Xu W, Tan L, Hu Y, Zhan Q, Lee CW, Hu D, Lian BQ, Kleffel S, Yang Y, Neiswender J, Khorasani AJ, Fang R, Lezcano C, Duncan LM, Scolyer RA, Thompson JF, Kakavand H, Houvras Y, Zon LI, Mihm MC, Kaiser UB, Schatton T, Woda BA, Murphy GF, Shi YG. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell. 2012 Sep 14; 150(6):1135-46. PMID: 22980977; PMCID: PMC3770275.
    Citations: 353     Fields:    Translation:HumansCells
  40. Hu Y, Peng Y, Brousseau L, Bouamrani A, Liu X, Ferrari M. Nanotexture Optimization by Oxygen Plasma of Mesoporous Silica Thin Film for Enrichment of Low Molecular Weight Peptides Captured from Human Serum. Sci China Chem. 2010 Nov 01; 53(11):2257-2264. PMID: 21179395.
    Citations: 1     
  41. Zhou J, Du YR, Qin WH, Hu YG, Huang YN, Bao L, Han D, Mansouri A, Xu GL. RIM-BP3 is a manchette-associated protein essential for spermiogenesis. Development. 2009 Feb; 136(3):373-82. PMID: 19091768.
    Citations: 28     Fields:    Translation:AnimalsCells
  42. Li SJ, Hu Y, Yan J, Mao YF, Li LW. [Upregulation of FasL/Fas expression and FasL/Fas-associated apoptosis in J774A.1 cells induced by Leptospira interrogans]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2008 11; 37(6):551-7. PMID: 19084951.
    Citations: 1     Fields:    Translation:AnimalsCells
  43. Chai G, Li L, Zhou W, Wu L, Zhao Y, Wang D, Lu S, Yu Y, Wang H, McNutt MA, Hu YG, Chen Y, Yang Y, Wu X, Otterson GA, Zhu WG. HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells. PLoS One. 2008 Jun 18; 3(6):e2445. PMID: 18560576.
    Citations: 30     Fields:    Translation:HumansCells
  44. Hu YG, Hirasawa R, Hu JL, Hata K, Li CL, Jin Y, Chen T, Li E, Rigolet M, Viegas-Péquignot E, Sasaki H, Xu GL. Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development. Hum Mol Genet. 2008 Sep 01; 17(17):2654-64. PMID: 18544626.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  45. Tang BE, Chen YY, Guo W, Mei DS, Xu Q, Hu Y, Shen YL, Xia Q. [COX-2 mediates U50488H-induced delayed cardioprotection in isolated rat heart]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2006 03; 35(2):165-71. PMID: 16610083.
    Citations:    Fields:    Translation:Animals
  46. Cheng JC, Weisenberger DJ, Gonzales FA, Liang G, Xu GL, Hu YG, Marquez VE, Jones PA. Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells. Mol Cell Biol. 2004 Feb; 24(3):1270-8. PMID: 14729971.
    Citations: 67     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.