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Elise Brooks Robinson, Sc.D.

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Overview
Dr. Robinson is an Assistant Professor of Epidemiology at the Harvard T.H. Chan School of Public Health and an Associate Member of the Broad Institute. She is also affiliated faculty in the Analytic and Translational Genetics Unit at Massachusetts General Hospital.

Robinson’s research focuses on the genetic epidemiology of behavior and cognition. She is interested in using genetic data to understand the biology of neurodevelopmental variation, and to study differences within and between psychiatric disorders.

Robinson’s research reflects her training in epidemiology and genetics. She received a Sc.D. in psychiatric epidemiology at the Harvard School of Public Health, supervised by Dr. Karestan Koenen. She completed postdoctoral training in the lab of Mark Daly at MGH and the Broad Institute, using statistical genetic approaches to study neurodevelopmental disorders.

For information on open positions in Dr. Robinson's group, contact erob@broadinstitute.org.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01MH119689 (ROBINSON, ELISE B) Jun 1, 2019 - Mar 31, 2024
    NIH/NIMH
    Rare genetic disorders in NeuroDev: Insight into the genetic and phenotypic heterogeneity of ID, ASD and ADHD in South African Populations
    Role: Principal Investigator
  2. R01MH111813 (ROBINSON, ELISE B) Sep 5, 2017 - May 31, 2022
    NIH/NIMH
    Phenotypic profiling of ASD risk
    Role: Principal Investigator
  3. NARSAD Young Investigator Award (ROBINSON, ELISE B) Jan 15, 2015 - Jan 15, 2018
    Behavior Brain Research Foundation
    Genotype to Phenotype Association in Autism Spectrum Disorder
    Role: Principal Investigator
  4. K01MH099286 (ROBINSON, ELISE B) Aug 1, 2013 - Jul 31, 2017
    NIH/NIMH
    The genomic bridge project (GBP)
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lal D, May P, Perez-Palma E, Samocha KE, Kosmicki JA, Robinson EB, Møller RS, Krause R, Nürnberg P, Weckhuysen S, De Jonghe P, Guerrini R, Niestroj LM, Du J, Marini C, Ware JS, Kurki M, Gormley P, Tang S, Wu S, Biskup S, Poduri A, Neubauer BA, Koeleman BPC, Helbig KL, Weber YG, Helbig I, Majithia AR, Palotie A, Daly MJ. Gene family information facilitates variant interpretation and identification of disease-associated genes in neurodevelopmental disorders. Genome Med. 2020 03 17; 12(1):28. PMID: 32183904.
    Citations:    
  2. Satterstrom FK, Walters RK, Singh T, Wigdor EM, Lescai F, Demontis D, Kosmicki JA, Grove J, Stevens C, Bybjerg-Grauholm J, Bækvad-Hansen M, Palmer DS, Maller JB, Nordentoft M, Mors O, Robinson EB, Hougaard DM, Werge TM, Bo Mortensen P, Neale BM, Børglum AD, Daly MJ. Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants. Nat Neurosci. 2019 12; 22(12):1961-1965. PMID: 31768057.
    Citations:    
  3. Taylor JL, Debost JPG, Morton SU, Wigdor EM, Heyne HO, Lal D, Howrigan DP, Bloemendal A, Larsen JT, Kosmicki JA, Weiner DJ, Homsy J, Seidman JG, Seidman CE, Agerbo E, McGrath JJ, Mortensen PB, Petersen L, Daly MJ, Robinson EB. Paternal-age-related de novo mutations and risk for five disorders. Nat Commun. 2019 07 10; 10(1):3043. PMID: 31292440.
    Citations:    
  4. Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, Nærland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnström K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos P, Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, Børglum AD. Identification of common genetic risk variants for autism spectrum disorder. Nat Genet. 2019 03; 51(3):431-444. PMID: 30804558.
    Citations:    
  5. Martin AR, Daly MJ, Robinson EB, Hyman SE, Neale BM. Predicting Polygenic Risk of Psychiatric Disorders. Biol Psychiatry. 2019 07 15; 86(2):97-109. PMID: 30737014.
    Citations:    
  6. Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, Gandal M, Goldstein JI, Grasby KL, Grove J, Gudmundsson OO, Hansen CS, Hauberg ME, Hollegaard MV, Howrigan DP, Huang H, Maller JB, Martin AR, Martin NG, Moran J, Pallesen J, Palmer DS, Pedersen CB, Pedersen MG, Poterba T, Poulsen JB, Ripke S, Robinson EB, Satterstrom FK, Stefansson H, Stevens C, Turley P, Walters GB, Won H, Wright MJ, Andreassen OA, Asherson P, Burton CL, Boomsma DI, Cormand B, Dalsgaard S, Franke B, Gelernter J, Geschwind D, Hakonarson H, Haavik J, Kranzler HR, Kuntsi J, Langley K, Lesch KP, Middeldorp C, Reif A, Rohde LA, Roussos P, Schachar R, Sklar P, Sonuga-Barke EJS, Sullivan PF, Thapar A, Tung JY, Waldman ID, Medland SE, Stefansson K, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Daly MJ, Faraone SV, Børglum AD, Neale BM. Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nat Genet. 2019 01; 51(1):63-75. PMID: 30478444.
    Citations:    Fields:    
  7. Mollon J, Knowles EEM, Mathias SR, Gur R, Peralta JM, Weiner DJ, Robinson EB, Gur RE, Blangero J, Almasy L, Glahn DC. Genetic influence on cognitive development between childhood and adulthood. Mol Psychiatry. 2018 Oct 19. PMID: 30644433.
    Citations:    Fields:    
  8. Shafee R, Nanda P, Padmanabhan JL, Tandon N, Alliey-Rodriguez N, Kalapurakkel S, Weiner DJ, Gur RE, Keefe RSE, Hill SK, Bishop JR, Clementz BA, Tamminga CA, Gershon ES, Pearlson GD, Keshavan MS, Sweeney JA, McCarroll SA, Robinson EB. Polygenic risk for schizophrenia and measured domains of cognition in individuals with psychosis and controls. Transl Psychiatry. 2018 04 12; 8(1):78. PMID: 29643358.
    Citations: 2     Fields:    Translation:Humans
  9. Weiner DJ, Wigdor EM, Ripke S, Walters RK, Kosmicki JA, Grove J, Samocha KE, Goldstein JI, Okbay A, Bybjerg-Grauholm J, Werge T, Hougaard DM, Taylor J, Skuse D, Devlin B, Anney R, Sanders SJ, Bishop S, Mortensen PB, Børglum AD, Smith GD, Daly MJ, Robinson EB. Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. Nat Genet. 2017 Jul; 49(7):978-985. PMID: 28504703.
    Citations: 22     Fields:    Translation:Humans
  10. Bishop SL, Farmer C, Bal V, Robinson EB, Willsey AJ, Werling DM, Havdahl KA, Sanders SJ, Thurm A. Identification of Developmental and Behavioral Markers Associated With Genetic Abnormalities in Autism Spectrum Disorder. Am J Psychiatry. 2017 06 01; 174(6):576-585. PMID: 28253736.
    Citations: 3     Fields:    Translation:Humans
  11. Kosmicki JA, Samocha KE, Howrigan DP, Sanders SJ, Slowikowski K, Lek M, Karczewski KJ, Cutler DJ, Devlin B, Roeder K, Buxbaum JD, Neale BM, MacArthur DG, Wall DP, Robinson EB, Daly MJ. Refining the role of de novo protein-truncating variants in neurodevelopmental disorders by using population reference samples. Nat Genet. 2017 Apr; 49(4):504-510. PMID: 28191890.
    Citations: 18     Fields:    Translation:Humans
  12. Germine L, Robinson EB, Smoller JW, Calkins ME, Moore TM, Hakonarson H, Daly MJ, Lee PH, Holmes AJ, Buckner RL, Gur RC, Gur RE. Association between polygenic risk for schizophrenia, neurocognition and social cognition across development. Transl Psychiatry. 2016 10 18; 6(10):e924. PMID: 27754483.
    Citations: 7     Fields:    Translation:Humans
  13. Ganna A, Genovese G, Howrigan DP, Byrnes A, Kurki M, Zekavat SM, Whelan CW, Kals M, Nivard MG, Bloemendal A, Bloom JM, Goldstein JI, Poterba T, Seed C, Handsaker RE, Natarajan P, Mägi R, Gage D, Robinson EB, Metspalu A, Salomaa V, Suvisaari J, Purcell SM, Sklar P, Kathiresan S, Daly MJ, McCarroll SA, Sullivan PF, Palotie A, Esko T, Hultman C, Neale BM. Ultra-rare disruptive and damaging mutations influence educational attainment in the general population. Nat Neurosci. 2016 12; 19(12):1563-1565. PMID: 27694993.
    Citations: 4     Fields:    Translation:Humans
  14. Robinson EB, St Pourcain B, Anttila V, Kosmicki JA, Bulik-Sullivan B, Grove J, Maller J, Samocha KE, Sanders SJ, Ripke S, Martin J, Hollegaard MV, Werge T, Hougaard DM, Neale BM, Evans DM, Skuse D, Mortensen PB, Børglum AD, Ronald A, Smith GD, Daly MJ. Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population. Nat Genet. 2016 05; 48(5):552-5. PMID: 26998691.
    Citations: 55     Fields:    Translation:Humans
  15. Robinson EB, Neale BM, Hyman SE. Genetic research in autism spectrum disorders. Curr Opin Pediatr. 2015 Dec; 27(6):685-91. PMID: 26371945.
    Citations: 13     Fields:    Translation:Humans
  16. Bulik-Sullivan B, Finucane HK, Anttila V, Gusev A, Day FR, Loh PR, Duncan L, Perry JR, Patterson N, Robinson EB, Daly MJ, Price AL, Neale BM. An atlas of genetic correlations across human diseases and traits. Nat Genet. 2015 Nov; 47(11):1236-41. PMID: 26414676.
    Citations: 281     Fields:    Translation:Humans
  17. Sanders SJ, He X, Willsey AJ, Ercan-Sencicek AG, Samocha KE, Cicek AE, Murtha MT, Bal VH, Bishop SL, Dong S, Goldberg AP, Jinlu C, Keaney JF, Klei L, Mandell JD, Moreno-De-Luca D, Poultney CS, Robinson EB, Smith L, Solli-Nowlan T, Su MY, Teran NA, Walker MF, Werling DM, Beaudet AL, Cantor RM, Fombonne E, Geschwind DH, Grice DE, Lord C, Lowe JK, Mane SM, Martin DM, Morrow EM, Talkowski ME, Sutcliffe JS, Walsh CA, Yu TW, Ledbetter DH, Martin CL, Cook EH, Buxbaum JD, Daly MJ, Devlin B, Roeder K, State MW. Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci. Neuron. 2015 Sep 23; 87(6):1215-1233. PMID: 26402605.
    Citations: 158     Fields:    Translation:Humans
  18. Taylor MJ, Robinson EB, Happé F, Bolton P, Freeman D, Ronald A. A longitudinal twin study of the association between childhood autistic traits and psychotic experiences in adolescence. Mol Autism. 2015; 6:44. PMID: 26199714.
    Citations: 3     Fields:    
  19. Roberts AL, Koenen KC, Lyall K, Robinson EB, Weisskopf MG. Association of autistic traits in adulthood with childhood abuse, interpersonal victimization, and posttraumatic stress. Child Abuse Negl. 2015 Jul; 45:135-42. PMID: 25957197.
    Citations: 5     Fields:    Translation:Humans
  20. Robinson EB, Samocha KE, Kosmicki JA, McGrath L, Neale BM, Perlis RH, Daly MJ. Autism spectrum disorder severity reflects the average contribution of de novo and familial influences. Proc Natl Acad Sci U S A. 2014 Oct 21; 111(42):15161-5. PMID: 25288738.
    Citations: 27     Fields:    Translation:Humans
  21. Samocha KE, Robinson EB, Sanders SJ, Stevens C, Sabo A, McGrath LM, Kosmicki JA, Rehnström K, Mallick S, Kirby A, Wall DP, MacArthur DG, Gabriel SB, DePristo M, Purcell SM, Palotie A, Boerwinkle E, Buxbaum JD, Cook EH, Gibbs RA, Schellenberg GD, Sutcliffe JS, Devlin B, Roeder K, Neale BM, Daly MJ. A framework for the interpretation of de novo mutation in human disease. Nat Genet. 2014 Sep; 46(9):944-50. PMID: 25086666.
    Citations: 191     Fields:    Translation:Humans
  22. Taylor MJ, Charman T, Robinson EB, Hayiou-Thomas ME, Happé F, Dale PS, Ronald A. Language and traits of autism spectrum conditions: evidence of limited phenotypic and etiological overlap. Am J Med Genet B Neuropsychiatr Genet. 2014 Oct; 165B(7):587-95. PMID: 25088445.
    Citations:    Fields:    Translation:Humans
  23. Robinson EB, Kirby A, Ruparel K, Yang J, McGrath L, Anttila V, Neale BM, Merikangas K, Lehner T, Sleiman PM, Daly MJ, Gur R, Gur R, Hakonarson H. The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort. Mol Psychiatry. 2015 Apr; 20(4):454-8. PMID: 25023143.
    Citations: 12     Fields:    Translation:Humans
  24. Hahn JW, McCormick MC, Silverman JG, Robinson EB, Koenen KC. Examining the impact of disability status on intimate partner violence victimization in a population sample. J Interpers Violence. 2014 Nov; 29(17):3063-85. PMID: 24860078.
    Citations: 3     Fields:    Translation:Humans
  25. Wiste A, Robinson EB, Milaneschi Y, Meier S, Ripke S, Clements CC, Fitzmaurice GM, Rietschel M, Penninx BW, Smoller JW, Perlis RH. Bipolar polygenic loading and bipolar spectrum features in major depressive disorder. Bipolar Disord. 2014 Sep; 16(6):608-16. PMID: 24725193.
    Citations: 6     Fields:    Translation:Humans
  26. EB Robinson, D Howrigan, J Yang, S Ripke, V Anttila, LE Duncan, L Jostins, JC Barrett, SE Medland, DG MacArthur, G Breen, MC O'Donovan, NR Wray, B Devlin, MJ Daly, PM Visscher, PF Sullivan, BM Neale. Response to ‘Predicting the diagnosis of autism spectrum disorder using gene pathway analysis’. Mol Psych. 2013. View Publication.
  27. McGrath LM, Cornelis MC, Lee PH, Robinson EB, Duncan LE, Barnett JH, Huang J, Gerber G, Sklar P, Sullivan P, Perlis RH, Smoller JW. Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2013 Dec; 162B(8):779-88. PMID: 24039173.
    Citations: 8     Fields:    Translation:Humans
  28. Robinson EB, Lichtenstein P, Anckarsäter H, Happé F, Ronald A. Examining and interpreting the female protective effect against autistic behavior. Proc Natl Acad Sci U S A. 2013 Mar 26; 110(13):5258-62. PMID: 23431162.
    Citations: 73     Fields:    Translation:HumansCTClinical Trials
  29. McGrath LM, Weill S, Robinson EB, Macrae R, Smoller JW. Bringing a developmental perspective to anxiety genetics. Dev Psychopathol. 2012 Nov; 24(4):1179-93. PMID: 23062290.
    Citations: 7     Fields:    Translation:Humans
  30. Robinson EB, Munir K, McCormick MC, Koenen KC, Santangelo SL. Brief report: no association between parental age and extreme social-communicative autistic traits in the general population. J Autism Dev Disord. 2011 Dec; 41(12):1733-7. PMID: 21350918.
    Citations: 3     Fields:    Translation:Humans
  31. Robinson EB, Koenen KC, McCormick MC, Munir K, Hallett V, Happé F, Plomin R, Ronald A. Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5%, 2.5%, and 1%). Arch Gen Psychiatry. 2011 Nov; 68(11):1113-21. PMID: 22065527.
    Citations: 78     Fields:    Translation:Humans
  32. Robinson EB, Koenen KC, McCormick MC, Munir K, Hallett V, Happé F, Plomin R, Ronald A. A multivariate twin study of autistic traits in 12-year-olds: testing the fractionable autism triad hypothesis. Behav Genet. 2012 Mar; 42(2):245-55. PMID: 21927971.
    Citations: 31     Fields:    Translation:Humans
  33. Robinson EB, Munir K, Munafò MR, Hughes M, McCormick MC, Koenen KC. Stability of autistic traits in the general population: further evidence for a continuum of impairment. J Am Acad Child Adolesc Psychiatry. 2011 Apr; 50(4):376-84. PMID: 21421177.
    Citations: 28     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.