Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Lester Kobzik, M.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01AI125152 (LU, QUAN) May 19, 2016 - Apr 30, 2020
    NIH
    Plasma Gelsolin as Immunotherapeutic for Antibiotic-Resistant Pneumonia
    Role: Principal Investigator
  2. R13AI109838 (KOBZIK, LESTER) Jan 1, 2014 - May 31, 2014
    NIH
    2014 Biology of Acute Respiratory Infection Gordon Research Conference and Semina
    Role: Principal Investigator
  3. R21ES023281 (KOBZIK, LESTER) Aug 30, 2013 - Jul 31, 2016
    NIH
    Transgenerational Susceptibility to Asthma from Air Pollution Exposure
    Role: Principal Investigator
  4. R01HL115778 (KOBZIK, LESTER) Jan 11, 2013 - Jul 31, 2017
    NIH
    Plasma Gelsolin and Host Defense After Lung Injury
    Role: Principal Investigator
  5. R21ES019825 (KOBZIK, LESTER) Jun 1, 2011 - May 31, 2014
    NIH
    RNAi Screen in Air Pollutant-Enhanced Influenza Infection
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bhattacharya J, Booy R, Casadevall A, Dela Cruz C, Fedson DS, Garcia JGN, Grohmann G, Hung IFN, Jacobson JR, Jennings LC, Kobzik L, Leligdowicz A, Liao JK, Martin JH, Musher DM, Serhan CN, Tashiro M. A practical treatment for COVID-19 and the next pandemic. Pharmacol Res Perspect. 2022 08; 10(4):e00988. PMID: 35837790; PMCID: PMC9284194.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  2. Joffre J, Wong E, Lawton S, Lloyd E, Nguyen N, Xu F, Sempio C, Kobzik L, Zlatanova I, Schumacher M, Klawitter J, Su H, Rabl K, Wilhelmsen K, Yeh CC, Hellman J. N-Oleoyl dopamine induces IL-10 via central nervous system TRPV1 and improves endotoxemia and sepsis outcomes. J Neuroinflammation. 2022 May 24; 19(1):118. PMID: 35610647; PMCID: PMC9131699.
    Citations:    Fields:    Translation:AnimalsCells
  3. Inde Z, Croker BA, Yapp C, Joshi GN, Spetz J, Fraser C, Qin X, Xu L, Deskin B, Ghelfi E, Webb G, Carlin AF, Zhu YP, Leibel SL, Garretson AF, Clark AE, Duran JM, Pretorius V, Crotty-Alexander LE, Li C, Lee JC, Sodhi C, Hackam DJ, Sun X, Hata AN, Kobzik L, Miller J, Park JA, Brownfield D, Jia H, Sarosiek KA. Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity. Sci Adv. 2021 08; 7(34). PMID: 34407940; PMCID: PMC8373124.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  4. Chatterjee S, Yabaji SM, Rukhlenko OS, Bhattacharya B, Waligurski E, Vallavoju N, Ray S, Kholodenko BN, Brown LE, Beeler AB, Ivanov AR, Kobzik L, Porco JA, Kramnik I. Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis. iScience. 2021 Aug 20; 24(8):102845. PMID: 34381970; PMCID: PMC8333345.
    Citations: 1     
  5. Bhattacharya B, Xiao S, Chatterjee S, Urbanowski M, Ordonez A, Ihms EA, Agrahari G, Lun S, Berland R, Pichugin A, Gao Y, Connor J, Ivanov AR, Yan BS, Kobzik L, Koo BB, Jain S, Bishai W, Kramnik I. The integrated stress response mediates necrosis in murine Mycobacterium tuberculosis granulomas. J Clin Invest. 2021 02 01; 131(3). PMID: 33301427; PMCID: PMC7843230.
    Citations: 4     Fields:    Translation:AnimalsCells
  6. Inde Z, Yapp C, Joshi GN, Spetz J, Fraser C, Deskin B, Ghelfi E, Sodhi C, Hackam DJ, Kobzik L, Croker BA, Brownfield D, Jia H, Sarosiek KA. Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity. bioRxiv. 2020 Sep 13. PMID: 32935109; PMCID: PMC7491524.
    Citations:    
  7. Gregory DJ, DeLoid GM, Salmon SL, Metzger DW, Kramnik I, Kobzik L. SON DNA-binding protein mediates macrophage autophagy and responses to intracellular infection. FEBS Lett. 2020 09; 594(17):2782-2799. PMID: 32484234.
    Citations: 1     Fields:    Translation:HumansCells
  8. Joffre J, Yeh CC, Wong E, Thete M, Xu F, Zlatanova I, Lloyd E, Kobzik L, Legrand M, Hellman J. Activation of CB1R Promotes Lipopolysaccharide-Induced IL-10 Secretion by Monocytic Myeloid-Derived Suppressive Cells and Reduces Acute Inflammation and Organ Injury. J Immunol. 2020 06 15; 204(12):3339-3350. PMID: 32385136; PMCID: PMC7276941.
    Citations: 9