Harvard Catalyst Profiles

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Suraj J Patel, M.D., Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K08DK125762 (PATEL, SURAJ J) Sep 15, 2020 - Jun 30, 2025
    Innate immune regulation of hepatic insulin sensitivity and metabolism
    Role: Principal Investigator
  2. R43AA023707 (PATEL, SURAJ J) Sep 20, 2014 - Aug 31, 2016
    Development of Gap Junction Inhibition Therapy for Alcoholic Liver Disease
    Role: Principal Investigator
  3. R43DK096862 (PATEL, SURAJ J) Aug 21, 2013 - Jul 31, 2017
    Development of a hepatoprotective strategy for preventing drug-induced liver inju
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Vannier AGL, Wardwell B, Fomin V, PeBenito A, Wolczynski N, Piaker S, Kedrin D, Chung RT, Schaefer E, Goodman R, Patel SJ, Luther J. Serum HMGB1 associates with liver disease and predicts readmission and mortality in patients with alcohol use disorder. Alcohol. 2021 Jun 10; 95:37-43. PMID: 34118353.
    Citations:    Fields:    
  2. Luther J, Khan S, Gala MK, Kedrin D, Sridharan G, Goodman RP, Garber JJ, Masia R, Diagacomo E, Adams D, King KR, Piaker S, Reinecker HC, Yarmush ML, Argemi J, Bataller R, Dienstag JL, Chung RT, Patel SJ. Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11667-11673. PMID: 32393626.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  3. Luther J, Gala MK, Borren N, Masia R, Goodman RP, Moeller IH, DiGiacomo E, Ehrlich A, Warren A, Yarmush ML, Ananthakrishnan A, Corey K, Kaplan LM, Bhatia S, Chung RT, Patel SJ. Hepatic connexin 32 associates with nonalcoholic fatty liver disease severity. Hepatol Commun. 2018 Jul; 2(7):786-797. PMID: 30202815.
    Citations: 4     
  4. Luther J, Gala M, Patel SJ, Dave M, Borren N, Xavier RJ, Ananthakrishnan AN. Loss of Response to Anti-Tumor Necrosis Factor Alpha Therapy in Crohn's Disease Is Not Associated with Emergence of Novel Inflammatory Pathways. Dig Dis Sci. 2018 03; 63(3):738-745. PMID: 29372477.
    Citations: 5     Fields:    Translation:Humans
  5. Kubiliun M, Patel SJ, Hur C, Dienstag JL, Luther J. Early liver transplantation for alcoholic hepatitis: Ready for primetime? J Hepatol. 2018 03; 68(3):380-382. PMID: 29175244.
    Citations: 2     Fields:    Translation:Humans
  6. Patel SJ, Luther J, Bohr S, Iracheta-Vellve A, Li M, King KR, Chung RT, Yarmush ML. A Novel Resolvin-Based Strategy for Limiting Acetaminophen Hepatotoxicity. Clin Transl Gastroenterol. 2016 Mar 17; 7:e153. PMID: 26986653.
    Citations: 9     Fields:    
  7. Bohr S, Patel SJ, Vasko R, Shen K, Golberg A, Berthiaume F, Yarmush ML. The Role of CHI3L1 (Chitinase-3-Like-1) in the Pathogenesis of Infections in Burns in a Mouse Model. PLoS One. 2015; 10(11):e0140440. PMID: 26528713.
    Citations: 7     Fields:    Translation:AnimalsCells
  8. Luther J, Garber JJ, Khalili H, Dave M, Bale SS, Jindal R, Motola DL, Luther S, Bohr S, Jeoung SW, Deshpande V, Singh G, Turner JR, Yarmush ML, Chung RT, Patel SJ. Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability. Cell Mol Gastroenterol Hepatol. 2015 Mar; 1(2):222-232. PMID: 26405687.
    Citations: 61     Fields:    
  9. Bohr S, Patel SJ, Vasko R, Shen K, Iracheta-Vellve A, Lee J, Bale SS, Chakraborty N, Brines M, Cerami A, Berthiaume F, Yarmush ML. Modulation of cellular stress response via the erythropoietin/CD131 heteroreceptor complex in mouse mesenchymal-derived cells. J Mol Med (Berl). 2015 Feb; 93(2):199-210. PMID: 25373867.
    Citations: 7     Fields:    Translation:AnimalsCells
  10. Patel SJ, Milwid JM, King KR, Bohr S, Iracheta-Velle A, Li M, Vitalo A, Parekkadan B, Jindal R, Yarmush ML. Erratum: Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure. Nat Biotechnol. 2014 Mar 10; 32(3):291. PMID: 24727782.
  11. Bohr S, Patel SJ, Vasko R, Shen K, Huang G, Yarmush ML, Berthiaume F. Highly upregulated Lhx2 in the Foxn1-/- nude mouse phenotype reflects a dysregulated and expanded epidermal stem cell niche. PLoS One. 2013; 8(5):e64223. PMID: 23696871.
    Citations: 4     Fields:    Translation:AnimalsCells
  12. Bohr S, Patel SJ, Shen K, Vitalo AG, Brines M, Cerami A, Berthiaume F, Yarmush ML. Alternative erythropoietin-mediated signaling prevents secondary microvascular thrombosis and inflammation within cutaneous burns. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3513-8. PMID: 23401545.
    Citations: 13     Fields:    Translation:AnimalsCells
  13. Bohr S, Patel SJ, Sarin D, Irimia D, Yarmush ML, Berthiaume F. Resolvin D2 prevents secondary thrombosis and necrosis in a mouse burn wound model. Wound Repair Regen. 2013 Jan-Feb; 21(1):35-43. PMID: 23110665.
    Citations: 47     Fields:    Translation:AnimalsCells
  14. Patel SJ, Milwid JM, King KR, Bohr S, Iracheta-Vellve A, Iracheta-Velle A, Li M, Vitalo A, Parekkadan B, Jindal R, Yarmush ML. Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure. Nat Biotechnol. 2012 Jan 15; 30(2):179-83. PMID: 22252509.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  15. Patel SJ, Jindal R, King KR, Tilles AW, Yarmush ML. The inflammatory response to double stranded DNA in endothelial cells is mediated by NF?B and TNFa. PLoS One. 2011; 6(5):e19910. PMID: 21611132.
    Citations: 6     Fields:    Translation:AnimalsCells
  16. Jindal R, Patel SJ, Yarmush ML. Tissue-engineered model for real-time monitoring of liver inflammation. Tissue Eng Part C Methods. 2011 Jan; 17(1):113-22. PMID: 20684748.
    Citations: 10     Fields:    Translation:AnimalsCells
  17. Patel SJ, King KR, Casali M, Yarmush ML. DNA-triggered innate immune responses are propagated by gap junction communication. Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):12867-72. PMID: 19617563.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  18. Rege K, Patel SJ, Megeed Z, Yarmush ML. Amphipathic peptide-based fusion peptides and immunoconjugates for the targeted ablation of prostate cancer cells. Cancer Res. 2007 Jul 01; 67(13):6368-75. PMID: 17616696.
    Citations: 24     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.