Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Braden Kuo, M.D.


Available: 06/16/14, Expires: 07/01/20

There are numerous projects from retrospective database analyses to prospective human physiological studies and clinical trials to understand the mechanisms of gut motility and perception in health and disease. Student's role would be to engage in help with a project or to engage in a retrospective data analysis in one of these areas with the goal of producing a presentable body of work/publication.

Disease entities and topics include: GI Motility, Functional GI disease, GERD, gastroparesis, dyspepsia, food ingestion, obesity, constipation, irritable bowel syndrome.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01DK112193 (KUO, BRADEN) Sep 25, 2016 - Aug 31, 2021
    New England Gastropareis Consortium: Neurobiology of Gastroparesis
    Role: Principal Investigator
  2. R21DK097499 (KUO, BRADEN) Sep 20, 2012 - Aug 31, 2014
    Brain Mechanisms for Autonomic Outflow and Nausea in Cyclic Vomiting Syndrome
    Role: Principal Investigator
  3. K23DK069614 (KUO, BRADEN) Jul 15, 2005 - Jun 30, 2010
    Functional Dyspepsia: Defining Central Circuits
    Role: Principal Investigator
  4. F32DK010157 (KUO, BRADEN) Jul 1, 2001
    Role: Principal Investigator
  5. M01RR001066 (SLAVIN, PETER L) Feb 1, 1978 - May 31, 2008
    General Clinical Research Center
    Role: Co-Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Cangemi DJ, Kuo B. Practical Perspectives in the Treatment of Nausea and Vomiting. J Clin Gastroenterol. 2019 Mar; 53(3):170-178. PMID: 30614944.
    Citations:    Fields:    
  2. Revicki DA, Speck RM, Lavoie S, Puelles J, Kuo B, Camilleri M, Almansa C, Parkman HP. The American neurogastroenterology and motility society gastroparesis cardinal symptom index-daily diary (ANMS GCSI-DD): Psychometric evaluation in patients with idiopathic or diabetic gastroparesis. Neurogastroenterol Motil. 2019 Apr; 31(4):e13553. PMID: 30734412.
  3. Lee AA, Rao S, Nguyen LA, Moshiree B, Sarosiek I, Schulman MI, Wo JM, Parkman HP, Wilding GE, McCallum RW, Hasler WL, Kuo B. Validation of Diagnostic and Performance Characteristics of the Wireless Motility Capsule in Patients With Suspected Gastroparesis. Clin Gastroenterol Hepatol. 2018 Dec 14. PMID: 30557741.
    Citations:    Fields:    
  4. Revicki DA, Lavoie S, Speck RM, Puelles J, Kuo B, Camilleri M, Almansa C, Parkman HP. The content validity of the ANMS GCSI-DD in patients with idiopathic or diabetic gastroparesis. J Patient Rep Outcomes. 2018 Dec 13; 2(1):61. PMID: 30547386.
  5. Parkman HP, Yamada G, Van Natta ML, Yates K, Hasler WL, Sarosiek I, Grover M, Schey R, Abell TL, Koch KL, Kuo B, Clarke J, Farrugia G, Nguyen L, Snape WJ, Miriel L, Tonascia J, Hamilton F, Pasricha PJ, McCallum RW. Ethnic, Racial, and Sex Differences in Etiology, Symptoms, Treatment, and Symptom Outcomes of Patients with Gastroparesis. Clin Gastroenterol Hepatol. 2018 Nov 04. PMID: 30404035.
    Citations:    Fields:    
  6. Staller K, Song M, Grodstein F, Matthews CA, Whitehead WE, Kuo B, Chan AT, Townsend MK. Physical Activity, BMI, and Risk of Fecal Incontinence in the Nurses' Health Study. Clin Transl Gastroenterol. 2018 Oct 25; 9(10):200. PMID: 30356052.
  7. Grover M, Gibbons SJ, Nair AA, Bernard CE, Zubair AS, Eisenman ST, Wilson LA, Miriel L, Pasricha PJ, Parkman HP, Sarosiek I, McCallum RW, Koch KL, Abell TL, Snape WJ, Kuo B, Shulman RJ, McKenzie TJ, Kellogg TA, Kendrick ML, Tonascia J, Hamilton FA, Farrugia G. Transcriptomic signatures reveal immune dysregulation in human diabetic and idiopathic gastroparesis. BMC Med Genomics. 2018 Aug 07; 11(1):62. PMID: 30086735.
    Citations:    Fields:    
  8. Staller K, Song M, Grodstein F, Whitehead WE, Matthews CA, Kuo B, Chan AT. Increased Long-term Dietary Fiber Intake Is Associated With a Decreased Risk of Fecal Incontinence in Older Women. Gastroenterology. 2018 09; 155(3):661-667.e1. PMID: 29758215.
    Citations:    Fields:    Translation:Humans
  9. Staller K, Barshop K, Kuo B, Ananthakrishnan AN. Depression but Not Symptom Severity is Associated With Work and School Absenteeism in Refractory Chronic Constipation. J Clin Gastroenterol. 2018 May/Jun; 52(5):407-412. PMID: 28059936.
    Citations:    Fields:    
  10. Surjanhata B, Barshop K, Staller K, Semler J, Guay L, Kuo B. Colonic motor response to wakening is blunted in slow transit constipation as detected by wireless motility capsule. Clin Transl Gastroenterol. 2018 04 25; 9(4):144. PMID: 29691377.
    Citations:    Translation:Humans
  11. Staller K, Thurler AH, Reynolds JS, Dimisko LR, McGovern R, Skarbinski KF, Kuo B. Gabapentin Improves Symptoms of Functional Dyspepsia in a Retrospective, Open-label Cohort Study. J Clin Gastroenterol. 2018 Apr 17. PMID: 29668559.
    Citations:    Fields:    
  12. Zar-Kessler C, Kuo B, Belkind-Gerson J. Botulinum toxin injection for childhood constipation is safe and can be effective regardless of anal sphincter dynamics. J Pediatr Surg. 2018 Apr; 53(4):693-697. PMID: 29395154.
    Citations:    Fields:    Translation:Humans
  13. Barshop K, Willingham FF, Brugge WR, Zukerberg LR, Kuo B. EMR is superior to rectal suction biopsy for analysis of enteric ganglia in constipation and dysmotility. Gastrointest Endosc. 2018 03; 87(3):876-880. PMID: 28893560.
    Citations: 1     Fields:    Translation:Humans
  14. Ko SJ, Park JW, Leem J, Kaptchuk TJ, Napadow V, Kuo B, Gerber J, Dimisko L, Yeo I, Lee J, Kim J. Influence of the patient-practitioner interaction context on acupuncture outcomes in functional dyspepsia: study protocol for a multicenter randomized controlled trial. BMC Complement Altern Med. 2017 Jul 14; 17(1):363. PMID: 28709452.
    Citations: 1     Fields:    Translation:Humans
  15. Zar-Kessler CAM, Belkind-Gerson J, Bender S, Kuo BM. Treatment of Functional Abdominal Pain With Antidepressants: Benefits, Adverse Effects, and the Gastroenterologist's Role. J Pediatr Gastroenterol Nutr. 2017 07; 65(1):16-21. PMID: 28644344.
    Citations: 1     Fields:    Translation:Humans
  16. Staller K, Townsend MK, Khalili H, Mehta R, Grodstein F, Whitehead WE, Matthews CA, Kuo B, Chan AT. Menopausal Hormone Therapy Is Associated With Increased Risk of Fecal Incontinence in Women After Menopause. Gastroenterology. 2017 06; 152(8):1915-1921.e1. PMID: 28209529.
    Citations: 2     Fields:    Translation:Humans
  17. Singh P, Kuo B. Central Aspects of Nausea and Vomiting in GI Disorders. Curr Treat Options Gastroenterol. 2016 Dec; 14(4):444-451. PMID: 27734216.
    Citations: 2     
  18. Yoon SS, Kuo B. Training in Gastrointestinal Motility. Dig Dis Sci. 2016 11; 61(11):3105-3107. PMID: 27638833.
    Citations:    Fields:    Translation:Humans
  19. Toschi N, Kim J, Sclocco R, Duggento A, Barbieri R, Kuo B, Napadow V. Motion sickness increases functional connectivity between visual motion and nausea-associated brain regions. Auton Neurosci. 2017 01; 202:108-113. PMID: 28245927.
    Citations: 1     Fields:    Translation:Humans
  20. Zar-Kessler CA, Belkind-Gerson J, Bender S, Kuo BM. Treatment of Functional Abdominal Pain with Antidepressants: Benefits, Side Effects and the Gastroenterologist's Role. J Pediatr Gastroenterol Nutr. 2016 Sep 16. PMID: 27642783.
  21. Tran K, Staller K, Macklin E, Goldstein A, Belkind-Gerson J, Kuo B. Need for Rectal Biopsy for Childhood Constipation Predicts Severity of Illness and Need for Laxatives. J Pediatr Gastroenterol Nutr. 2016 06; 62(6):834-9. PMID: 26551318.
    Citations: 2     Fields:    Translation:Humans
  22. Zar-Kessler C, Karaa A, Sims KB, Clarke V, Kuo B. Understanding the gastrointestinal manifestations of Fabry disease: promoting prompt diagnosis. Therap Adv Gastroenterol. 2016 Jul; 9(4):626-34. PMID: 27366228; PMCID: PMC4913334.
    Citations: 1     
  23. Gubatan J, Staller K, Barshop K, Kuo B. Cannabis Abuse Is Increasing and Associated with Increased Emergency Department Utilization in Gastroenterology Patients. Dig Dis Sci. 2016 07; 61(7):1844-52. PMID: 26935430.
    Citations: 6     Fields:    Translation:Humans
  24. Singh P, Yoon SS, Kuo B. Nausea: a review of pathophysiology and therapeutics. Therap Adv Gastroenterol. 2016 Jan; 9(1):98-112. PMID: 26770271; PMCID: PMC4699282.
    Citations: 5     
  25. Staller K, Khalili H, Kuo B. Constipation prophylaxis reduces length of stay in elderly hospitalized heart failure patients with home laxative use. J Gastroenterol Hepatol. 2015 Nov; 30(11):1596-602. PMID: 25969162.
    Citations: 1     Fields:    Translation:Humans
  26. Singh P, Staller K, Barshop K, Dai E, Newman J, Yoon S, Castel S, Kuo B. Patients with irritable bowel syndrome-diarrhea have lower disease-specific quality of life than irritable bowel syndrome-constipation. World J Gastroenterol. 2015 Jul 14; 21(26):8103-9. PMID: 26185382; PMCID: PMC4499353.
    Citations: 13     Fields:    Translation:Humans
  27. Staller K, Barshop K, Ananthakrishnan AN, Kuo B. Rectosigmoid Localization of Radiopaque Markers Does Not Correlate with Prolonged Balloon Expulsion in Chronic Constipation: Results from a Multicenter Cohort. Am J Gastroenterol. 2015 Jul; 110(7):1049-55. PMID: 25964224.
    Citations: 3     Fields:    Translation:Humans
  28. Barshop K, Kuo B. Connecting the dots between gastrointestinal motility and symptoms using wireless motility capsule testing. Dig Dis Sci. 2015 May; 60(5):1120-2. PMID: 25577271.
    Citations: 1     Fields:    Translation:Humans
  29. Kuo B, Bhasin M, Jacquart J, Scult MA, Slipp L, Riklin EI, Lepoutre V, Comosa N, Norton BA, Dassatti A, Rosenblum J, Thurler AH, Surjanhata BC, Hasheminejad NN, Kagan L, Slawsby E, Rao SR, Macklin EA, Fricchione GL, Benson H, Libermann TA, Korzenik J, Denninger JW. Genomic and clinical effects associated with a relaxation response mind-body intervention in patients with irritable bowel syndrome and inflammatory bowel disease. PLoS One. 2015; 10(4):e0123861. PMID: 25927528.
    Citations: 13     Fields:    Translation:HumansCellsCTClinical Trials
  30. Sclocco R, Citi L, Garcia RG, Cerutti S, Bianchi AM, Kuo B, Napadow V, Barbieri R. Combining sudomotor nerve impulse estimation with fMRI to investigate the central sympathetic response to nausea. Conf Proc IEEE Eng Med Biol Soc. 2015; 2015:4683-6. PMID: 26737339.
    Citations: 1     Fields:    Translation:Humans
  31. Barshop K, Kuo B. The investigational drug camicinal for the treatment of gastroparesis. Expert Opin Investig Drugs. 2015 Jan; 24(1):133-140. PMID: 25341626.
    Citations: 1     Fields:    
  32. Sclocco R, Kim J, Garcia RG, Sheehan JD, Beissner F, Bianchi AM, Cerutti S, Kuo B, Barbieri R, Napadow V. Brain Circuitry Supporting Multi-Organ Autonomic Outflow in Response to Nausea. Cereb Cortex. 2016 Feb; 26(2):485-97. PMID: 25115821; PMCID: PMC4712791.
    Citations: 10     Fields:    Translation:Humans
  33. Sheu EG, Nau P, Nath B, Kuo B, Rattner DW. A comparative trial of laparoscopic magnetic sphincter augmentation and Nissen fundoplication. Surg Endosc. 2015 Mar; 29(3):505-9. PMID: 25012804.
    Citations: 14     Fields:    Translation:Humans
  34. Tran K, Kuo B, Zibaitis A, Bhattacharya S, Cote C, Belkind-Gerson J. Effect of propofol on anal sphincter pressure during anorectal manometry. J Pediatr Gastroenterol Nutr. 2014 Apr; 58(4):495-7. PMID: 24121151.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  35. Belkind-Gerson J, Surjanhata B, Kuo B, Goldstein AM. Bear-down maneuver is a useful adjunct in the evaluation of children with chronic constipation. J Pediatr Gastroenterol Nutr. 2013 Dec; 57(6):775-9. PMID: 23945314.
    Citations: 1     Fields:    Translation:Humans
  36. Thurler AH, Kuo B. From heave to leave: understanding cyclic vomiting syndrome. Gastroenterol Nurs. 2013 Nov-Dec; 36(6):407-13. PMID: 24304524.
    Citations:    Fields:    Translation:Humans
  37. Green AD, Belkind-Gerson J, Surjanhata BC, Mousa H, Kuo B, Di Lorenzo C. Wireless motility capsule test in children with upper gastrointestinal symptoms. J Pediatr. 2013 Jun; 162(6):1181-7. PMID: 23290514.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  38. Belkind-Gerson J, Goldstein AM, Kuo B. Balloon expulsion test as a screen for outlet obstruction in children with chronic constipation. J Pediatr Gastroenterol Nutr. 2013 Jan; 56(1):23-6. PMID: 22847462.
    Citations: 1     Fields:    Translation:Humans
  39. Seeger JD, Quinn S, Earnest DL, Lembo A, Kuo B, Rivero E, Walker AM. The Zelnorm epidemiologic study (ZEST): a cohort study evaluating incidence of abdominal and pelvic surgery related to tegaserod treatment. BMC Gastroenterol. 2012 Nov 30; 12:171. PMID: 23198861; PMCID: PMC3536557.
    Citations:    Fields:    Translation:Humans
  40. Tran K, Brun R, Kuo B. Evaluation of regional and whole gut motility using the wireless motility capsule: relevance in clinical practice. Therap Adv Gastroenterol. 2012 Jul; 5(4):249-60. PMID: 22778790; PMCID: PMC3388524.
    Citations: 15     
  41. Napadow V, Sheehan JD, Kim J, Lacount LT, Park K, Kaptchuk TJ, Rosen BR, Kuo B. The brain circuitry underlying the temporal evolution of nausea in humans. Cereb Cortex. 2013 Apr; 23(4):806-13. PMID: 22473843; PMCID: PMC3593575.
    Citations: 43     Fields:    Translation:Humans
  42. Brun R, Staller K, Viner S, Kuo B. Endoscopically assisted water perfusion esophageal manometry with minimal sedation: technique, indications, and implication on the clinical management. J Clin Gastroenterol. 2011 Oct; 45(9):759-63. PMID: 21602703; PMCID: PMC4432032.
    Citations: 1     Fields:    Translation:Humans
  43. Kuo B, Maneerattanaporn M, Lee AA, Baker JR, Wiener SM, Chey WD, Wilding GE, Hasler WL. Generalized transit delay on wireless motility capsule testing in patients with clinical suspicion of gastroparesis, small intestinal dysmotility, or slow transit constipation. Dig Dis Sci. 2011 Oct; 56(10):2928-38. PMID: 21625964.
    Citations: 16     Fields:    Translation:Humans
  44. LaCount LT, Barbieri R, Park K, Kim J, Brown EN, Kuo B, Napadow V. Static and dynamic autonomic response with increasing nausea perception. Aviat Space Environ Med. 2011 Apr; 82(4):424-33. PMID: 21485400; PMCID: PMC3137518.
    Citations: 11     Fields:    Translation:Humans
  45. Michalek W, Semler JR, Kuo B. Impact of acid suppression on upper gastrointestinal pH and motility. Dig Dis Sci. 2011 Jun; 56(6):1735-42. PMID: 21086166.
    Citations: 9     Fields:    Translation:Humans
  46. Brun R, Kuo B. Functional dyspepsia. Therap Adv Gastroenterol. 2010 May; 3(3):145-64. PMID: 21180597; PMCID: PMC3002577.
    Citations: 27     
  47. Kloetzer L, Chey WD, McCallum RW, Koch KL, Wo JM, Sitrin M, Katz LA, Lackner JM, Parkman HP, Wilding GE, Semler JR, Hasler WL, Kuo B. Motility of the antroduodenum in healthy and gastroparetics characterized by wireless motility capsule. Neurogastroenterol Motil. 2010 May; 22(5):527-33, e117. PMID: 20122128.
    Citations: 23     Fields:    Translation:Humans
  48. Lee A, Kuo B. Metoclopramide in the treatment of diabetic gastroparesis. Expert Rev Endocrinol Metab. 2010; 5(5):653-662. PMID: 21278804.
    Citations: 12     
  49. Saad RJ, Rao SS, Koch KL, Kuo B, Parkman HP, McCallum RW, Sitrin MD, Wilding GE, Semler JR, Chey WD. Do stool form and frequency correlate with whole-gut and colonic transit? Results from a multicenter study in constipated individuals and healthy controls. Am J Gastroenterol. 2010 Feb; 105(2):403-11. PMID: 19888202.
    Citations: 48     Fields:    Translation:Humans
  50. Hasler WL, Saad RJ, Rao SS, Wilding GE, Parkman HP, Koch KL, McCallum RW, Kuo B, Sarosiek I, Sitrin MD, Semler JR, Chey WD. Heightened colon motor activity measured by a wireless capsule in patients with constipation: relation to colon transit and IBS. Am J Physiol Gastrointest Liver Physiol. 2009 Dec; 297(6):G1107-14. PMID: 19808653.
    Citations: 19     Fields:    Translation:Humans
  51. Kwong KK, Kloetzer L, Wong KK, Ren JQ, Kuo B, Jiang Y, Chen YI, Chan ST, Young GS, Wong ST. Bioluminescence imaging of heme oxygenase-1 upregulation in the Gua Sha procedure. J Vis Exp. 2009 Aug 28; (30). PMID: 19718012; PMCID: PMC3149908.
    Citations: 7     Fields:    Translation:AnimalsCells
  52. Brun R, Kuo B. Upper gastrointestinal promotility drugs: not all uniform? Indian J Gastroenterol. 2009 Jul-Aug; 28(4):123-5. PMID: 19937420.
    Citations:    Fields:    Translation:Humans
  53. Rao SS, Kuo B, McCallum RW, Chey WD, DiBaise JK, Hasler WL, Koch KL, Lackner JM, Miller C, Saad R, Semler JR, Sitrin MD, Wilding GE, Parkman HP. Investigation of colonic and whole-gut transit with wireless motility capsule and radiopaque markers in constipation. Clin Gastroenterol Hepatol. 2009 May; 7(5):537-44. PMID: 19418602.
    Citations: 73     Fields:    Translation:Humans
  54. Gaman A, Bucur MC, Kuo B. Therapeutic advances in functional gastrointestinal disease: irritable bowel syndrome. Therap Adv Gastroenterol. 2009 May 01; 2(3):169-181. PMID: 19936327.
    Citations: 3     
  55. Gaman A, Kuo B. Neuromodulatory processes of the brain-gut axis. Neuromodulation. 2008 Oct 01; 11(4):249-259. PMID: 19844605.
    Citations: 12     Fields:    
  56. Hasler WL, Coleski R, Chey WD, Koch KL, McCallum RW, Wo JM, Kuo B, Sitrin MD, Katz LA, Hwang J, Semler JR, Parkman HP. Differences in intragastric pH in diabetic vs. idiopathic gastroparesis: relation to degree of gastric retention. Am J Physiol Gastrointest Liver Physiol. 2008 Jun; 294(6):G1384-91. PMID: 18403619.
    Citations: 9     Fields:    Translation:Humans
  57. Kuo B, McCallum RW, Koch KL, Sitrin MD, Wo JM, Chey WD, Hasler WL, Lackner JM, Katz LA, Semler JR, Wilding GE, Parkman HP. Comparison of gastric emptying of a nondigestible capsule to a radio-labelled meal in healthy and gastroparetic subjects. Aliment Pharmacol Ther. 2008 Jan 15; 27(2):186-96. PMID: 17973643.
    Citations: 73     Fields:    Translation:Humans
  58. Podovei M, Kuo B. Irritable bowel syndrome: a practical review. South Med J. 2006 Nov; 99(11):1235-42; quiz 1243-4, 1284. PMID: 17195419.
    Citations:    Fields:    Translation:Humans
  59. Cole JA, Yeaw JM, Cutone JA, Kuo B, Huang Z, Earnest DL, Walker AM. The incidence of abdominal and pelvic surgery among patients with irritable bowel syndrome. Dig Dis Sci. 2005 Dec; 50(12):2268-75. PMID: 16416174.
    Citations: 11     Fields:    Translation:Humans
  60. Kuo B, Camilleri M, Burton D, Viramontes B, McKinzie S, Thomforde G, O'Connor MK, Brinkmann BH. Effects of 5-HT(3) antagonism on postprandial gastric volume and symptoms in humans. Aliment Pharmacol Ther. 2002 Feb; 16(2):225-33. PMID: 11860405.
    Citations: 14     Fields:    Translation:HumansCTClinical Trials
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Kuo's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (216)
Co-Authors (40)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.