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Jonathan C. Kagan, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI116550 (KAGAN, JONATHAN C) Dec 13, 2016 - Jan 31, 2026
    Characterization of the myddosome, a protein complex that controls TLR signaling
    Role: Principal Investigator
  2. R56AI113141 (KAGAN, JONATHAN C) Aug 1, 2014 - Jul 31, 2015
    Initiation and regulation of antibacterial innate immunity
    Role: Principal Investigator
  3. R56AI103082 (KAGAN, JONATHAN C) May 16, 2013 - Apr 30, 2015
    Defining non-transcriptional innate immune responses to bacterial endotoxin
    Role: Principal Investigator
  4. R56AI093589 (KAGAN, JONATHAN C) Mar 1, 2011 - Aug 31, 2022
    Initiation and Regulation of Antiviral Innate Immunity
    Role: Principal Investigator
  5. R01AI093589 (KAGAN, JONATHAN C) Mar 1, 2011 - Feb 28, 2021
    Initiation and Regulation of Antiviral Innate Immunity
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Evavold CL, Kagan JC. Diverse Control Mechanisms of the Interleukin-1 Cytokine Family. Front Cell Dev Biol. 2022; 10:910983. PMID: 35832789; PMCID: PMC9272893.
  2. Mosallanejad K, Kagan JC. Control of innate immunity by the cGAS-STING pathway. Immunol Cell Biol. 2022 Jul; 100(6):409-423. PMID: 35485309; PMCID: PMC9250635.
    Citations:    Fields:    Translation:Animals
  3. Ferreira AR, Gouveia A, Magalhães AC, Valença I, Marques M, Kagan JC, Ribeiro D. Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner. Front Cell Dev Biol. 2022; 10:871977. PMID: 35445031; PMCID: PMC9014249.
  4. Maeda K, Zachos NC, Orzalli MH, Schmieder SS, Chang D, Bugda Gwilt K, Doucet M, Baetz NW, Lee S, Crawford SE, Estes MK, Kagan JC, Turner JR, Lencer WI. Depletion of the apical endosome in response to viruses and bacterial toxins provides cell-autonomous host defense at mucosal surfaces. Cell Host Microbe. 2022 02 09; 30(2):216-231.e5. PMID: 35143768; PMCID: PMC8852832.
    Citations:    Fields:    Translation:Cells
  5. Cao A, Kagan JC. Gasdermin Pore Forming Activities that Promote Inflammation from Living and Dead Cells. J Mol Biol. 2022 02 28; 434(4):167427. PMID: 34973239; PMCID: PMC8844208.
    Citations:    Fields:    Translation:Humans
  6. Ragland SA, Kagan JC. Cytosolic detection of phagosomal bacteria-Mechanisms underlying PAMP exodus from the phagosome into the cytosol. Mol Microbiol. 2021 12; 116(6):1420-1432. PMID: 34738270; PMCID: PMC8688326.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  7. Coronas-Serna JM, Del Val E, Kagan JC, Molina M, Cid VJ. Heterologous Expression and Assembly of Human TLR Signaling Components in Saccharomyces cerevisiae. Biomolecules. 2021 11 22; 11(11). PMID: 34827735; PMCID: PMC8615643.
    Citations:    Fields:    Translation:AnimalsCells
  8. Ferreira AR, Marques M, Ramos B, Kagan JC, Ribeiro D. Emerging roles of peroxisomes in viral infections. Trends Cell Biol. 2022 02; 32(2):124-139. PMID: 34696946.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  9. Kagan J, Goodman GN, Oh R, Whitworth D, Gladden D, Graves G, Nguyen A, Shrestha O, Burge G, Smolskis M, Andrews J, Cramer B, Lane HC. NIAID ClinRegs-a Public Database of Country Clinical Research Regulatory and Ethics Requirements: Design and Utilization Analysis. Clin Infect Dis. 2021 10 05; 73(7):1296-1301. PMID: 34050748; PMCID: PMC8492127.
    Citations:    Fields:    Translation:HumansPHPublic Health
  10. Zhivaki D, Kagan JC. Innate immune detection of lipid oxidation as a threat assessment strategy. Nat Rev Immunol. 2022 05; 22(5):322-330. PMID: 34548649; PMCID: PMC8454293.
    Citations: 11     Fields:    Translation:HumansCells
  11. Fischer FA, Mies LFM, Nizami S, Pantazi E, Danielli S, Demarco B, Ohlmeyer M, Lee MSJ, Coban C, Kagan JC, Di Daniel E, Bezbradica JS. TBK1 and IKKe act like an OFF switch to limit NLRP3 inflammasome pathway activation. Proc Natl Acad Sci U S A. 2021 09 21; 118(38). PMID: 34518217; PMCID: PMC8463895.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  12. Devant P, Cao A, Kagan JC. Evolution-inspired redesign of the LPS receptor caspase-4 into an interleukin-1ß converting enzyme. Sci Immunol. 2021 08 10; 6(62). PMID: 34734155; PMCID: PMC8559778.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  13. Evavold CL, Hafner-Bratkovic I, Devant P, D'Andrea JM, Ngwa EM, Boršic E, Doench JG, LaFleur MW, Sharpe AH, Thiagarajah JR, Kagan JC. Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway. Cell. 2021 08 19; 184(17):4495-4511.e19. PMID: 34289345; PMCID: PMC8380731.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  14. Maiti G, Frikeche J, Lam CY, Biswas A, Shinde V, Samanovic M, Kagan JC, Mulligan MJ, Chakravarti S. Matrix lumican endocytosed by immune cells controls receptor ligand trafficking to promote TLR4 and restrict TLR9 in sepsis. Proc Natl Acad Sci U S A. 2021 07 06; 118(27). PMID: 34215697.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  15. Zhivaki D, Kagan JC. NLRP3 inflammasomes that induce antitumor immunity. Trends Immunol. 2021 07; 42(7):575-589. PMID: 34034975.
    Citations: 7     Fields:    Translation:Animals
  16. Orzalli MH, Prochera A, Payne L, Smith A, Garlick JA, Kagan JC. Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells. Immunity. 2021 07 13; 54(7):1447-1462.e5. PMID: 33979579; PMCID: PMC8594743.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  17. Ernandes MJ, Kagan JC. Interferon-Independent Restriction of RNA Virus Entry and Replication by a Class of Damage-Associated Molecular Patterns. mBio. 2021 04 13; 12(2). PMID: 33849978.
    Citations: 2     Fields:    Translation:HumansCells
  18. Gauthier AE, Chandler CE, Poli V, Gardner FM, Tekiau A, Smith R, Bonham KS, Cordes EE, Shank TM, Zanoni I, Goodlett DR, Biller SJ, Ernst RK, Rotjan RD, Kagan JC. Deep-sea microbes as tools to refine the rules of innate immune pattern recognition. Sci Immunol. 2021 03 12; 6(57). PMID: 33712473; PMCID: PMC8367048.
    Citations: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  19. Zhivaki D, Borriello F, Chow OA, Doran B, Fleming I, Theisen DJ, Pallis P, Shalek AK, Sokol CL, Zanoni I, Kagan JC. Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity. Cell Rep. 2020 11 17; 33(7):108381. PMID: 33207188.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  20. Prestes EB, Alves LS, Rodrigues DAS, Dutra FF, Fernandez PL, Paiva CN, Kagan JC, Bozza MT. Mitochondrial Reactive Oxygen Species Participate in Signaling Triggered by Heme in Macrophages and upon Hemolysis. J Immunol. 2020 11 15; 205(10):2795-2805. PMID: 33037139.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  21. Magupalli VG, Negro R, Tian Y, Hauenstein AV, Di Caprio G, Skillern W, Deng Q, Orning P, Alam HB, Maliga Z, Sharif H, Hu JJ, Evavold CL, Kagan JC, Schmidt FI, Fitzgerald KA, Kirchhausen T, Li Y, Wu H. HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science. 2020 09 18; 369(6510). PMID: 32943500.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  22. Fitzgerald KA, Kagan JC. Toll-like Receptors and the Control of Immunity. Cell. 2020 03 19; 180(6):1044-1066. PMID: 32164908; PMCID: PMC9358771.
    Citations: 283     Fields:    Translation:HumansAnimalsCells
  23. Stanifer ML, Mukenhirn M, Muenchau S, Pervolaraki K, Kanaya T, Albrecht D, Odendall C, Hielscher T, Haucke V, Kagan JC, Bartfeld S, Ohno H, Boulant S. Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells. Nat Microbiol. 2020 01; 5(1):181-191. PMID: 31686029.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  24. Lieberman J, Wu H, Kagan JC. Gasdermin D activity in inflammation and host defense. Sci Immunol. 2019 09 06; 4(39). PMID: 31492708.
    Citations: 42     Fields:    Translation:HumansAnimals
  25. Evavold CL, Kagan JC. Inflammasomes: Threat-Assessment Organelles of the Innate Immune System. Immunity. 2019 10 15; 51(4):609-624. PMID: 31473100.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  26. Rotjan RD, Sharp KH, Gauthier AE, Yelton R, Lopez EMB, Carilli J, Kagan JC, Urban-Rich J. Patterns, dynamics and consequences of microplastic ingestion by the temperate coral, Astrangia poculata. Proc Biol Sci. 2019 06 26; 286(1905):20190726. PMID: 31238843; PMCID: PMC6599985.
    Citations: 10     Fields:    Translation:Animals
  27. Barnett KC, Kagan JC. Lipids that directly regulate innate immune signal transduction. Innate Immun. 2020 01; 26(1):4-14. PMID: 31180799.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  28. Odendall C, Kagan JC. Host-Encoded Sensors of Bacteria: Our Windows into the Microbial World. Microbiol Spectr. 2019 05; 7(3). PMID: 31152521.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  29. de Oliveira Mann CC, Orzalli MH, King DS, Kagan JC, Lee ASY, Kranzusch PJ. Modular Architecture of the STING C-Terminal Tail Allows Interferon and NF-?B Signaling Adaptation. Cell Rep. 2019 04 23; 27(4):1165-1175.e5. PMID: 31018131.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  30. Tan Y, Kagan JC. Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility. Cell. 2019 04 04; 177(2):384-398.e11. PMID: 30853218; PMCID: PMC6710629.
    Citations: 25     Fields:    Translation:AnimalsCells
  31. Barnett KC, Coronas-Serna JM, Zhou W, Ernandes MJ, Cao A, Kranzusch PJ, Kagan JC. Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA. Cell. 2019 03 07; 176(6):1432-1446.e11. PMID: 30827685.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  32. Evavold CL, Kagan JC. Defying Death: The (W)hole Truth about the Fate of GSDMD Pores. Immunity. 2019 01 15; 50(1):15-17. PMID: 30650374.
    Citations: 10     Fields:    Translation:Cells
  33. Shaw DK, Tate AT, Schneider DS, Levashina EA, Kagan JC, Pal U, Fikrig E, Pedra JHF. Vector Immunity and Evolutionary Ecology: The Harmonious Dissonance. Trends Immunol. 2018 11; 39(11):862-873. PMID: 30301592; PMCID: PMC6218297.
    Citations: 18     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  34. Chow J, Kagan JC. The Fly Way of Antiviral Resistance and Disease Tolerance. Adv Immunol. 2018; 140:59-93. PMID: 30366519.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  35. Orzalli MH, Smith A, Jurado KA, Iwasaki A, Garlick JA, Kagan JC. An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication. Mol Cell. 2018 09 06; 71(5):825-840.e6. PMID: 30100266; PMCID: PMC6411291.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  36. Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. Retraction Notice to: The Unfolded Protein Response Element IRE1a Senses Bacterial Proteins Invading the ER to Activate RIG-I and Innate Immune Signaling. Cell Host Microbe. 2018 04 11; 23(4):571. PMID: 29649448; PMCID: PMC5916756.
    Citations: 1     Fields:    
  37. Franz KM, Neidermyer WJ, Tan YJ, Whelan SPJ, Kagan JC. STING-dependent translation inhibition restricts RNA virus replication. Proc Natl Acad Sci U S A. 2018 02 27; 115(9):E2058-E2067. PMID: 29440426.
    Citations: 61     Fields:    Translation:AnimalsCells
  38. Tan Y, Kagan JC. Biochemical Isolation of the Myddosome from Murine Macrophages. Methods Mol Biol. 2018; 1714:79-95. PMID: 29177857.
    Citations:    Fields:    Translation:AnimalsCells
  39. Evavold CL, Ruan J, Tan Y, Xia S, Wu H, Kagan JC. The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages. Immunity. 2018 01 16; 48(1):35-44.e6. PMID: 29195811.
    Citations: 325     Fields:    Translation:HumansAnimalsCells
  40. Zanoni I, Tan Y, Di Gioia M, Springstead JR, Kagan JC. By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation. Immunity. 2017 10 17; 47(4):697-709.e3. PMID: 29045901.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  41. Evavold CL, Kagan JC. How Inflammasomes Inform Adaptive Immunity. J Mol Biol. 2018 01 19; 430(2):217-237. PMID: 28987733.
    Citations: 58     Fields:    Translation:HumansAnimals
  42. Odendall C, Voak AA, Kagan JC. Type III IFNs Are Commonly Induced by Bacteria-Sensing TLRs and Reinforce Epithelial Barriers during Infection. J Immunol. 2017 11 01; 199(9):3270-3279. PMID: 28954888; PMCID: PMC5679450.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  43. Chow J, Márka Z, Bartos I, Márka S, Kagan JC. Environmental Stress Causes Lethal Neuro-Trauma during Asymptomatic Viral Infections. Cell Host Microbe. 2017 Jul 12; 22(1):48-60.e5. PMID: 28704652.
    Citations: 3     Fields:    Translation:AnimalsCells
  44. Orzalli MH, Kagan JC. Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection. Trends Cell Biol. 2017 11; 27(11):800-809. PMID: 28642032.
    Citations: 75     Fields:    Translation:HumansAnimalsCells
  45. Franz KM, Kagan JC. Innate Immune Receptors as Competitive Determinants of Cell Fate. Mol Cell. 2017 Jun 15; 66(6):750-760. PMID: 28622520.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  46. Kagan JC. Lipopolysaccharide Detection across the Kingdoms of Life. Trends Immunol. 2017 10; 38(10):696-704. PMID: 28551077.
    Citations: 19     Fields:    Translation:HumansAnimals
  47. Kieser KJ, Kagan JC. Multi-receptor detection of individual bacterial products by the innate immune system. Nat Rev Immunol. 2017 Jun; 17(6):376-390. PMID: 28461704.
    Citations: 65     Fields:    Translation:HumansAnimalsCells
  48. Odendall C, Kagan JC. Activation and pathogenic manipulation of the sensors of the innate immune system. Microbes Infect. 2017 Apr - May; 19(4-5):229-237. PMID: 28093320.
    Citations: 15     Fields:    Translation:HumansCells
  49. Tan Y, Kagan JC. Microbe-inducible trafficking pathways that control Toll-like receptor signaling. Traffic. 2017 01; 18(1):6-17. PMID: 27731905.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  50. Rosadini CV, Kagan JC. Early innate immune responses to bacterial LPS. Curr Opin Immunol. 2017 Feb; 44:14-19. PMID: 27842237.
    Citations: 109     Fields:    Translation:HumansAnimalsCells
  51. Guerrant RL, Leite AM, Pinkerton R, Medeiros PH, Cavalcante PA, DeBoer M, Kosek M, Duggan C, Gewirtz A, Kagan JC, Gauthier AE, Swann J, Mayneris-Perxachs J, Bolick DT, Maier EA, Guedes MM, Moore SR, Petri WA, Havt A, Lima IF, Prata MM, Michaleckyj JC, Scharf RJ, Sturgeon C, Fasano A, Lima AA. Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil. PLoS One. 2016; 11(9):e0158772. PMID: 27690129; PMCID: PMC5045163.
    Citations: 86     Fields:    
  52. Orzalli MH, Kagan JC. A one-protein signaling pathway in the innate immune system. Sci Immunol. 2016 Aug 19; 1(2):eaah6184. PMID: 28783697.
    Citations: 3     Fields:    
  53. Kagan JC. Editorial overview: Emerging concepts in host-virus interactions. Curr Opin Microbiol. 2016 08; 32:xii-xiii. PMID: 27426076.
    Citations:    Fields:    Translation:HumansAnimals
  54. Akula MK, Shi M, Jiang Z, Foster CE, Miao D, Li AS, Zhang X, Gavin RM, Forde SD, Germain G, Carpenter S, Rosadini CV, Gritsman K, Chae JJ, Hampton R, Silverman N, Gravallese EM, Kagan JC, Fitzgerald KA, Kastner DL, Golenbock DT, Bergo MO, Wang D. Control of the innate immune response by the mevalonate pathway. Nat Immunol. 2016 08; 17(8):922-9. PMID: 27270400; PMCID: PMC4955724.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  55. Magalhães AC, Ferreira AR, Gomes S, Vieira M, Gouveia A, Valença I, Islinger M, Nascimento R, Schrader M, Kagan JC, Ribeiro D. Peroxisomes are platforms for cytomegalovirus' evasion from the cellular immune response. Sci Rep. 2016 05 16; 6:26028. PMID: 27181750.
    Citations: 21     Fields:    Translation:HumansCells
  56. Kagan J, Giang DD, Iademarco MF, Phung VT, Lau CY, Quang NN. Assessing Clinical Research Capacity in Vietnam: A Framework for Strengthening Capability for Clinical Trials in Developing Countries. Public Health Rep. 2016 May-Jun; 131(3):396-403. PMID: 27252559; PMCID: PMC4869086.
    Citations: 1     Fields:    Translation:Humans
  57. Zanoni I, Tan Y, Di Gioia M, Broggi A, Ruan J, Shi J, Donado CA, Shao F, Wu H, Springstead JR, Kagan JC. An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells. Science. 2016 Jun 03; 352(6290):1232-6. PMID: 27103670; PMCID: PMC5111085.
    Citations: 190     Fields:    Translation:AnimalsCells
  58. Ferreira AR, Magalhães AC, Camões F, Gouveia A, Vieira M, Kagan JC, Ribeiro D. Hepatitis C virus NS3-4A inhibits the peroxisomal MAVS-dependent antiviral signalling response. J Cell Mol Med. 2016 Apr; 20(4):750-7. PMID: 26865163; PMCID: PMC5125814.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  59. Rosadini CV, Zanoni I, Odendall C, Green ER, Paczosa MK, Philip NH, Brodsky IE, Mecsas J, Kagan JC. A Single Bacterial Immune Evasion Strategy Dismantles Both MyD88 and TRIF Signaling Pathways Downstream of TLR4. Cell Host Microbe. 2015 Dec 09; 18(6):682-93. PMID: 26651944; PMCID: PMC4685476.
    Citations: 21     Fields:    Translation:AnimalsCells
  60. Tan Y, Zanoni I, Cullen TW, Goodman AL, Kagan JC. Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria. Immunity. 2015 Nov 17; 43(5):909-22. PMID: 26546281.
    Citations: 67     Fields:    Translation:HumansCells
  61. Chow J, Franz KM, Kagan JC. PRRs are watching you: Localization of innate sensing and signaling regulators. Virology. 2015 May; 479-480:104-9. PMID: 25800355.
    Citations: 46     Fields:    Translation:Cells
  62. Odendall C, Kagan JC. The unique regulation and functions of type III interferons in antiviral immunity. Curr Opin Virol. 2015 Jun; 12:47-52. PMID: 25771505.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  63. Rosadini CV, Kagan JC. Microbial strategies for antagonizing Toll-like-receptor signal transduction. Curr Opin Immunol. 2015 Feb; 32:61-70. PMID: 25615700; PMCID: PMC4336813.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  64. Brubaker SW, Bonham KS, Zanoni I, Kagan JC. Innate immune pattern recognition: a cell biological perspective. Annu Rev Immunol. 2015; 33:257-90. PMID: 25581309; PMCID: PMC5146691.
    Citations: 544     Fields:    Translation:HumansAnimalsCells
  65. Gwadz M, Cleland CM, Belkin M, Ritchie A, Leonard N, Riedel M, Banfield A, Colon P, Elharrar V, Kagan J, Mildvan D. ACT2 peer-driven intervention increases enrollment into HIV/AIDS medical studies among African Americans/Blacks and Hispanics: A cluster randomized controlled trial. AIDS Behav. 2014 Dec; 18(12):2409-22. PMID: 24961193; PMCID: PMC4451823.
    Citations: 10     Fields:    Translation:HumansPHPublic Health
  66. Kagan JC, Barton GM. Emerging principles governing signal transduction by pattern-recognition receptors. Cold Spring Harb Perspect Biol. 2014 Nov 13; 7(3):a016253. PMID: 25395297.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  67. Kagan JC, Magupalli VG, Wu H. SMOCs: supramolecular organizing centres that control innate immunity. Nat Rev Immunol. 2014 12; 14(12):821-6. PMID: 25359439; PMCID: PMC4373346.
    Citations: 106     Fields:    Translation:HumansAnimalsCells
  68. Kagan JC. Common mechanisms activate plant guard receptors and TLR4. Trends Immunol. 2014 Oct; 35(10):454-6. PMID: 25224694.
    Citations: 2     Fields:    Translation:Animals
  69. Teigler JE, Kagan JC, Barouch DH. Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J Virol. 2014 Sep; 88(18):10354-63. PMID: 24991003.
    Citations: 31     Fields:    Translation:HumansCells
  70. Odendall C, Dixit E, Stavru F, Bierne H, Franz KM, Durbin AF, Boulant S, Gehrke L, Cossart P, Kagan JC. Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat Immunol. 2014 Aug; 15(8):717-26. PMID: 24952503; PMCID: PMC4106986.
    Citations: 195     Fields:    Translation:HumansAnimalsCells
  71. Bonham KS, Kagan JC. Endosomes as platforms for NOD-like receptor signaling. Cell Host Microbe. 2014 May 14; 15(5):523-5. PMID: 24832447.
    Citations: 9     Fields:    Translation:HumansCells
  72. Tan Y, Kagan JC. A cross-disciplinary perspective on the innate immune responses to bacterial lipopolysaccharide. Mol Cell. 2014 Apr 24; 54(2):212-23. PMID: 24766885.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  73. Brubaker SW, Gauthier AE, Mills EW, Ingolia NT, Kagan JC. A bicistronic MAVS transcript highlights a class of truncated variants in antiviral immunity. Cell. 2014 Feb 13; 156(4):800-11. PMID: 24529381.
    Citations: 73     Fields:    Translation:HumansAnimalsCells
  74. Bonham KS, Orzalli MH, Hayashi K, Wolf AI, Glanemann C, Weninger W, Iwasaki A, Knipe DM, Kagan JC. A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction. Cell. 2014 Feb 13; 156(4):705-16. PMID: 24529375.
    Citations: 107     Fields:    Translation:AnimalsCells
  75. Franz KM, Kagan JC. Finding a needle in a haystack of needles - a productive hunt for interferon stimulated genes with antiviral activity. Immunol Cell Biol. 2014 Mar; 92(3):205-7. PMID: 24418815.
    Citations:    Fields:    Translation:HumansAnimals
  76. Kagan JC. Immunology. Sensing endotoxins from within. Science. 2013 Sep 13; 341(6151):1184-5. PMID: 24031006.
    Citations: 6     Fields:    Translation:AnimalsCells
  77. Kagan JC, Horng T. NLRP3 inflammasome activation: CD36 serves double duty. Nat Immunol. 2013 Aug; 14(8):772-4. PMID: 23867926.
    Citations: 13     Fields:    Translation:Animals
  78. Kagan JC. Recognition for an innate explorer. Cell. 2013 Jul 18; 154(2):261-4. PMID: 23870114.
    Citations:    Fields:    Translation:HumansAnimalsCells
  79. Cho JA, Lee AH, Platzer B, Cross BCS, Gardner BM, De Luca H, Luong P, Harding HP, Glimcher LH, Walter P, Fiebiger E, Ron D, Kagan JC, Lencer WI. The unfolded protein response element IRE1a senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host Microbe. 2013 May 15; 13(5):558-569. PMID: 23684307; PMCID: PMC3766372.
    Citations: 63     Fields:    Translation:HumansCells
  80. Odendall C, Kagan JC. Peroxisomes and the antiviral responses of mammalian cells. Subcell Biochem. 2013; 69:67-75. PMID: 23821143.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  81. Dixit E, Kagan JC. Intracellular pathogen detection by RIG-I-like receptors. Adv Immunol. 2013; 117:99-125. PMID: 23611287; PMCID: PMC3947775.
    Citations: 82     Fields:    Translation:HumansAnimalsCells
  82. Kagan JC. Signaling organelles of the innate immune system. Cell. 2012 Dec 07; 151(6):1168-78. PMID: 23217704.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  83. Velupillai P, Sung CK, Andrews E, Moran J, Beier D, Kagan J, Benjamin T. Polymorphisms in toll-like receptor 4 underlie susceptibility to tumor induction by the mouse polyomavirus. J Virol. 2012 Nov; 86(21):11541-7. PMID: 22896604.
    Citations: 5     Fields:    Translation:AnimalsCells
  84. Kagan JC. Defining the subcellular sites of innate immune signal transduction. Trends Immunol. 2012 Sep; 33(9):442-8. PMID: 22817912.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  85. Kagan JC, Iwasaki A. Phagosome as the organelle linking innate and adaptive immunity. Traffic. 2012 Aug; 13(8):1053-61. PMID: 22577865.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  86. Marek LR, Kagan JC. Phosphoinositide binding by the Toll adaptor dMyD88 controls antibacterial responses in Drosophila. Immunity. 2012 Apr 20; 36(4):612-22. PMID: 22464168.
    Citations: 29     Fields:    Translation:AnimalsCells
  87. Zanoni I, Ostuni R, Marek LR, Barresi S, Barbalat R, Barton GM, Granucci F, Kagan JC. CD14 controls the LPS-induced endocytosis of Toll-like receptor 4. Cell. 2011 Nov 11; 147(4):868-80. PMID: 22078883.
    Citations: 382     Fields:    Translation:AnimalsCells
  88. Schwartz CE, Kunwar PS, Greve DN, Kagan J, Snidman NC, Bloch RB. A phenotype of early infancy predicts reactivity of the amygdala in male adults. Mol Psychiatry. 2012 Oct; 17(10):1042-50. PMID: 21894151.
    Citations: 36     Fields:    Translation:Humans
  89. Edison N, Zuri D, Maniv I, Bornstein B, Lev T, Gottfried Y, Kemeny S, Garcia-Fernandez M, Kagan J, Larisch S. The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo. Cell Death Differ. 2012 Feb; 19(2):356-68. PMID: 21869827.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  90. Wang S, Villablanca EJ, De Calisto J, Gomes DC, Nguyen DD, Mizoguchi E, Kagan JC, Reinecker HC, Hacohen N, Nagler C, Xavier RJ, Rossi-Bergmann B, Chen YB, Blomhoff R, Snapper SB, Mora JR. MyD88-dependent TLR1/2 signals educate dendritic cells with gut-specific imprinting properties. J Immunol. 2011 Jul 01; 187(1):141-50. PMID: 21646294; PMCID: PMC3119749.
    Citations: 37     Fields:    Translation:AnimalsCells
  91. Marek LR, Kagan JC. Deciphering the function of nucleic acid sensing TLRs one regulatory step at a time. Front Biosci (Landmark Ed). 2011 06 01; 16(6):2060-8. PMID: 21622162; PMCID: PMC3947766.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  92. Wang L, Trebicka E, Fu Y, Waggoner L, Akira S, Fitzgerald KA, Kagan JC, Cherayil BJ. Regulation of lipopolysaccharide-induced translation of tumor necrosis factor-alpha by the toll-like receptor 4 adaptor protein TRAM. J Innate Immun. 2011; 3(5):437-46. PMID: 21494017; PMCID: PMC3186711.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  93. Liao AP, Salajegheh M, Nazareno R, Kagan JC, Jubin RG, Greenberg SA. Interferon ß is associated with type 1 interferon-inducible gene expression in dermatomyositis. Ann Rheum Dis. 2011 May; 70(5):831-6. PMID: 21177291.
    Citations: 33     Fields:    Translation:HumansCells
  94. Kagan JC. Recycling endosomes and TLR signaling--the Rab11 GTPase leads the way. Immunity. 2010 Oct 29; 33(4):578-80. PMID: 21029967.
    Citations: 4     Fields:    
  95. Dixit E, Boulant S, Zhang Y, Lee AS, Odendall C, Shum B, Hacohen N, Chen ZJ, Whelan SP, Fransen M, Nibert ML, Superti-Furga G, Kagan JC. Peroxisomes are signaling platforms for antiviral innate immunity. Cell. 2010 May 14; 141(4):668-81. PMID: 20451243.
    Citations: 390     Fields:    Translation:HumansAnimalsCells
  96. Kagan JC. "Complementing" toll signaling. Sci Signal. 2010 May 04; 3(120):pe15. PMID: 20442416.
    Citations: 6     Fields:    Translation:HumansCells
  97. Wang L, Harrington L, Trebicka E, Shi HN, Kagan JC, Hong CC, Lin HY, Babitt JL, Cherayil BJ. Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice. J Clin Invest. 2009 Nov; 119(11):3322-8. PMID: 19809161; PMCID: PMC2769199.
    Citations: 76     Fields:    Translation:AnimalsCells
  98. Barton GM, Kagan JC. A cell biological view of Toll-like receptor function: regulation through compartmentalization. Nat Rev Immunol. 2009 Aug; 9(8):535-42. PMID: 19556980.
    Citations: 318     Fields:    Translation:HumansAnimalsCells
  99. Kagan JC, Su T, Horng T, Chow A, Akira S, Medzhitov R. TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat Immunol. 2008 Apr; 9(4):361-8. PMID: 18297073.
    Citations: 569     Fields:    Translation:HumansAnimalsCells
  100. Kagan JC, Medzhitov R. Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell. 2006 Jun 02; 125(5):943-55. PMID: 16751103.
    Citations: 355     Fields:    Translation:HumansAnimalsCells
  101. Barton GM, Kagan JC, Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol. 2006 Jan; 7(1):49-56. PMID: 16341217.
    Citations: 221     Fields:    Translation:Animals
  102. Lambert JS, Moye J, Plaeger SF, Stiehm ER, Bethel J, Mofenson LM, Mathieson B, Kagan J, Rosenblatt H, Paxton H, Suter H, Landay A. Association of selected phenotypic markers of lymphocyte activation and differentiation with perinatal human immunodeficiency virus transmission and infant infection. Clin Diagn Lab Immunol. 2005 May; 12(5):622-31. PMID: 15879023; PMCID: PMC1112077.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
  103. Mildvan D, Spritzler J, Grossberg SE, Fahey JL, Johnston DM, Schock BR, Kagan J. Serum neopterin, an immune activation marker, independently predicts disease progression in advanced HIV-1 infection. Clin Infect Dis. 2005 Mar 15; 40(6):853-8. PMID: 15736019.
    Citations: 37     Fields:    Translation:Humans
  104. Kagan JC, Murata T, Roy CR. Analysis of Rab1 recruitment to vacuoles containing Legionella pneumophila. Methods Enzymol. 2005; 403:71-81. PMID: 16473578.
    Citations: 7     Fields:    Translation:AnimalsCells
  105. Nagai H, Cambronne ED, Kagan JC, Amor JC, Kahn RA, Roy CR. A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells. Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3):826-31. PMID: 15613486; PMCID: PMC545534.
    Citations: 148     Fields:    Translation:AnimalsCells
  106. Mildvan D, Bosch RJ, Kim RS, Spritzler J, Haas DW, Kuritzkes D, Kagan J, Nokta M, DeGruttola V, Moreno M, Landay A. Immunophenotypic markers and antiretroviral therapy (IMART): T cell activation and maturation help predict treatment response. J Infect Dis. 2004 May 15; 189(10):1811-20. PMID: 15122517.
    Citations: 14     Fields:    Translation:HumansCellsCTClinical Trials
  107. Kagan JC, Stein MP, Pypaert M, Roy CR. Legionella subvert the functions of Rab1 and Sec22b to create a replicative organelle. J Exp Med. 2004 May 03; 199(9):1201-11. PMID: 15117975; PMCID: PMC2211909.
    Citations: 139     Fields:    Translation:AnimalsCells
  108. Guignot J, Caron E, Beuzón C, Bucci C, Kagan J, Roy C, Holden DW. Microtubule motors control membrane dynamics of Salmonella-containing vacuoles. J Cell Sci. 2004 Mar 01; 117(Pt 7):1033-45. PMID: 14970261.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  109. Spritzler J, Mildvan D, Russo A, Asthana D, Livnat D, Schock B, Kagan J, Landay A, Haas DW. Can immune markers predict subsequent discordance between immunologic and virologic responses to antiretroviral therapy? Adult AIDS Clinical Trials Group. Clin Infect Dis. 2003 Aug 15; 37(4):551-8. PMID: 12905140.
    Citations: 5     Fields:    Translation:HumansCells
  110. Jonathan C. Kagan. Cellular and Molecular Aspects of Legionella pneumophila transport to the endoplasmic reticulum. 2003.
  111. Kagan JC, Roy CR. Legionella phagosomes intercept vesicular traffic from endoplasmic reticulum exit sites. Nat Cell Biol. 2002 Dec; 4(12):945-54. PMID: 12447391.
    Citations: 204     Fields:    Translation:AnimalsCells
  112. Nagai H, Kagan JC, Zhu X, Kahn RA, Roy CR. A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes. Science. 2002 Jan 25; 295(5555):679-82. PMID: 11809974.
    Citations: 238     Fields:    Translation:HumansAnimalsCells
  113. Biederman J, Hirshfeld-Becker DR, Rosenbaum JF, Hérot C, Friedman D, Snidman N, Kagan J, Faraone SV. Further evidence of association between behavioral inhibition and social anxiety in children. Am J Psychiatry. 2001 Oct; 158(10):1673-9. PMID: 11579001.
    Citations: 190     Fields:    Translation:Humans
  114. Spencer T, Biederman J, Wilens T, Faraone S, Prince J, Gerard K, Doyle R, Parekh A, Kagan J, Bearman SK. Efficacy of a mixed amphetamine salts compound in adults with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry. 2001 Aug; 58(8):775-82. PMID: 11483144.
    Citations: 52     Fields:    Translation:HumansCTClinical Trials
  115. Kagan J. Biological constraint, cultural variety, and psychological structures. Ann N Y Acad Sci. 2001 May; 935:177-90. PMID: 11411164.
    Citations:    Fields:    Translation:Humans
  116. Smoller JW, Rosenbaum JF, Biederman J, Susswein LS, Kennedy J, Kagan J, Snidman N, Laird N, Tsuang MT, Faraone SV, Schwarz A, Slaugenhaupt SA. Genetic association analysis of behavioral inhibition using candidate loci from mouse models. Am J Med Genet. 2001 Apr 08; 105(3):226-35. PMID: 11353440.
    Citations: 13     Fields:    Translation:HumansAnimals
  117. Spencer TJ, Biederman J, Faraone S, Mick E, Coffey B, Geller D, Kagan J, Bearman SK, Wilens T. Impact of tic disorders on ADHD outcome across the life cycle: findings from a large group of adults with and without ADHD. Am J Psychiatry. 2001 Apr; 158(4):611-7. PMID: 11282697.
    Citations: 16     Fields:    Translation:Humans
  118. Rosenbaum JF, Biederman J, Hirshfeld-Becker DR, Kagan J, Snidman N, Friedman D, Nineberg A, Gallery DJ, Faraone SV. A controlled study of behavioral inhibition in children of parents with panic disorder and depression. Am J Psychiatry. 2000 Dec; 157(12):2002-10. PMID: 11097967.
    Citations: 47     Fields:    Translation:Humans
  119. Coers J, Kagan JC, Matthews M, Nagai H, Zuckman DM, Roy CR. Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth. Mol Microbiol. 2000 Nov; 38(4):719-36. PMID: 11115108.
    Citations: 79     Fields:    Translation:HumansCells
  120. Schwartz CE, Snidman N, Kagan J. Adolescent social anxiety as an outcome of inhibited temperament in childhood. J Am Acad Child Adolesc Psychiatry. 1999 Aug; 38(8):1008-15. PMID: 10434493.
    Citations: 199     Fields:    Translation:Humans
  121. Grillon C, Merikangas KR, Dierker L, Snidman N, Arriaga RI, Kagan J, Donzella B, Dikel T, Nelson C. Startle potentiation by threat of aversive stimuli and darkness in adolescents: a multi-site study. Int J Psychophysiol. 1999 Apr; 32(1):63-73. PMID: 10192009.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  122. Lieberman J, Skolnik PR, Parkerson GR, Fabry JA, Landry B, Bethel J, Kagan J. Safety of autologous, ex vivo-expanded human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte infusion in HIV-infected patients. Blood. 1997 Sep 15; 90(6):2196-206. PMID: 9310470.
    Citations: 30     Fields:    Translation:HumansCellsCTClinical Trials
  123. Gortmaker SL, Kagan J, Caspi A, Silva PA. Daylength during pregnancy and shyness in children: results from northern and southern hemispheres. Dev Psychobiol. 1997 Sep; 31(2):107-14. PMID: 9298636.
    Citations: 8     Fields:    Translation:Humans
  124. Goodman E, Amick BC, Rezendes MO, Tarlov AR, Rogers WH, Kagan J. Influences of gender and social class on adolescents' perceptions of health. Arch Pediatr Adolesc Med. 1997 Sep; 151(9):899-904. PMID: 9308867.
    Citations: 9     Fields:    Translation:Humans
  125. Mildvan D, Landay A, De Gruttola V, Machado SG, Kagan J. An approach to the validation of markers for use in AIDS clinical trials. Clin Infect Dis. 1997 May; 24(5):764-74. PMID: 9142767.
    Citations: 19     Fields:    Translation:Humans
  126. Nicholson J, Kidd P, Mandy F, Livnat D, Kagan J. Three-color supplement to the NIAID DAIDS guideline for flow cytometric immunophenotyping. Cytometry. 1996 Sep 15; 26(3):227-30. PMID: 8889396.
    Citations: 18     Fields:    Translation:HumansCells
  127. Valentine FT, Kundu S, Haslett PA, Katzenstein D, Beckett L, Spino C, Borucki M, Vasquez M, Smith G, Korvick J, Kagan J, Merigan TC. A randomized, placebo-controlled study of the immunogenicity of human immunodeficiency virus (HIV) rgp160 vaccine in HIV-infected subjects with > or = 400/mm3 CD4 T lymphocytes (AIDS Clinical Trials Group Protocol 137). J Infect Dis. 1996 Jun; 173(6):1336-46. PMID: 8648205.
    Citations: 9     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
  128. Connelly MC, Knight M, Giorgi JV, Kagan J, Landay AL, Parker JW, Page E, Spino C, Wilkening C, Mercolino TJ. Standardization of absolute CD4+ lymphocyte counts across laboratories: an evaluation of the Ortho CytoronAbsolute flow cytometry system on normal donors. Cytometry. 1995 Sep 15; 22(3):200-10. PMID: 8556951.
    Citations: 7     Fields:    Translation:Humans
  129. Landay AL, Brambilla D, Pitt J, Hillyer G, Golenbock D, Moye J, Landesman S, Kagan J. Interlaboratory variability of CD8 subset measurements by flow cytometry and its applications to multicenter clinical trials. NAID/NICHD Women and Infants Transmission Study Group. Clin Diagn Lab Immunol. 1995 Jul; 2(4):462-8. PMID: 7583925; PMCID: PMC170180.
    Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
  130. Biederman J, Rosenbaum JF, Bolduc-Murphy EA, Faraone SV, Chaloff J, Hirshfeld DR, Kagan J. A 3-year follow-up of children with and without behavioral inhibition. J Am Acad Child Adolesc Psychiatry. 1993 Jul; 32(4):814-21. PMID: 8340303.
    Citations: 95     Fields:    Translation:Humans
  131. Rosenbaum JF, Biederman J, Bolduc-Murphy EA, Faraone SV, Chaloff J, Hirshfeld DR, Kagan J. Behavioral inhibition in childhood: a risk factor for anxiety disorders. Harv Rev Psychiatry. 1993 May-Jun; 1(1):2-16. PMID: 9384823.
    Citations: 53     Fields:    Translation:Humans
  132. Kagan J, Gelman R, Waxdal M, Kidd P. NIAID Division of AIDS flow cytometry quality assessment program. Ann N Y Acad Sci. 1993 Mar 20; 677:50-2. PMID: 8494245.
    Citations: 4     Fields:    Translation:HumansCells
  133. Gelman R, Cheng SC, Kidd P, Waxdal M, Kagan J. Assessment of the effects of instrumentation, monoclonal antibody, and fluorochrome on flow cytometric immunophenotyping: a report based on 2 years of the NIAID DAIDS flow cytometry quality assessment program. Clin Immunol Immunopathol. 1993 Feb; 66(2):150-62. PMID: 7680972.
    Citations: 16     Fields:    Translation:Humans
  134. Rosenbaum JF, Biederman J, Bolduc EA, Hirshfeld DR, Faraone SV, Kagan J. Comorbidity of parental anxiety disorders as risk for childhood-onset anxiety in inhibited children. Am J Psychiatry. 1992 Apr; 149(4):475-81. PMID: 1554032.
    Citations: 13     Fields:    Translation:Humans
  135. Hirshfeld DR, Rosenbaum JF, Biederman J, Bolduc EA, Faraone SV, Snidman N, Reznick JS, Kagan J. Stable behavioral inhibition and its association with anxiety disorder. J Am Acad Child Adolesc Psychiatry. 1992 Jan; 31(1):103-11. PMID: 1537760.
    Citations: 134     Fields:    Translation:Humans
  136. Cyr C, South V, Saltzman A, Felder S, Ricca GA, Jaye M, Huebner K, Kagan J, Croce CM, Schlessinger J, et al. Cloning, expression of the human substance K receptor, and analysis of its role in mitogenesis. Ann N Y Acad Sci. 1991; 632:426-7. PMID: 1659297.
    Citations:    Fields:    Translation:HumansAnimalsCells
  137. Rosenbaum JF, Biederman J, Hirshfeld DR, Bolduc EA, Faraone SV, Kagan J, Snidman N, Reznick JS. Further evidence of an association between behavioral inhibition and anxiety disorders: results from a family study of children from a non-clinical sample. J Psychiatr Res. 1991; 25(1-2):49-65. PMID: 2027095.
    Citations: 31     Fields:    Translation:Humans
  138. Kris RM, South V, Saltzman A, Felder S, Ricca GA, Jaye M, Huebner K, Kagan J, Croce CM, Schlessinger J. Cloning and expression of the human substance K receptor and analysis of its role in mitogenesis. Cell Growth Differ. 1991 Jan; 2(1):15-22. PMID: 1848773.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  139. Bell IR, Jasnoski ML, Kagan J, King DS. Depression and allergies: survey of a nonclinical population. Psychother Psychosom. 1991; 55(1):24-31. PMID: 1866437.
    Citations: 20     Fields:    Translation:Humans
  140. Wang TP, Kagan J, Lee S, Keiderling T. The hemolysis of erythrocytes by singlet oxygen generated in the gas phase. Photochem Photobiol. 1990 Oct; 52(4):753-6. PMID: 2089422.
    Citations:    Fields:    Translation:Humans
  141. Bell IR, Jasnoski ML, Kagan J, King DS. Is allergic rhinitis more frequent in young adults with extreme shyness? A preliminary survey. Psychosom Med. 1990 Sep-Oct; 52(5):517-25. PMID: 2247557.
    Citations: 7     Fields:    Translation:Humans
  142. Kozbor D, Cassatella MA, Lessin S, Kagan J, Finver S, Faust J, Trinchieri G, Croce CM. Expression and function of gamma delta- and alpha beta-T cell receptor heterodimers on human somatic T cell hybrids. J Immunol. 1990 May 15; 144(10):3677-83. PMID: 1692058.
    Citations: 3     Fields:    Translation:HumansCells
  143. Biederman J, Rosenbaum JF, Hirshfeld DR, Faraone SV, Bolduc EA, Gersten M, Meminger SR, Kagan J, Snidman N, Reznick JS. Psychiatric correlates of behavioral inhibition in young children of parents with and without psychiatric disorders. Arch Gen Psychiatry. 1990 Jan; 47(1):21-6. PMID: 2294852.
    Citations: 68     Fields:    Translation:Humans
  144. Rosenbaum JF, Biederman J, Gersten M, Hirshfeld DR, Meminger SR, Herman JB, Kagan J, Reznick JS, Snidman N. Behavioral inhibition in children of parents with panic disorder and agoraphobia. A controlled study. Arch Gen Psychiatry. 1988 May; 45(5):463-70. PMID: 3358645.
    Citations: 41     Fields:    Translation:Humans
  145. Azar Y, Falek PR, Kagan J, Ben-Sasson SZ. In vivo activity of affinity-purified helper factor from antigen-specific helper clone. J Immunol. 1985 Mar; 134(3):1717-22. PMID: 2578517.
    Citations:    Fields:    Translation:AnimalsCells
  146. Ben-Sasson SZ, Kagan J. Antigen-induced proliferation of murine T-lymphocytes in vitro. II. The effect of different macrophage populations on the antigen-induced proliferative response. J Immunol Methods. 1981; 41(3):321-31. PMID: 6971903.
    Citations:    Fields:    Translation:AnimalsCells
  147. Ben-Sasson SZ, Kagan J. In vitro selection of murine antigen-specific T-lymphocytes. I. Description of selection procedure. J Immunol Methods. 1981; 42(3):291-304. PMID: 6169763.
    Citations: 1     Fields:    Translation:AnimalsCells
  148. Kagan J, Ben-Sasson SZ. Antigen-induced proliferation of murine T-lymphocytes in vitro. I. Characterization of the lymphocyte culture system. J Immunol Methods. 1980; 37(1):15-27. PMID: 6968800.
    Citations: 1     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.