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profileAugusto Ampil Litonjua, M.D.

TitleAssociate Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressBrigham and Women's Hospital
Channing Division of Network Medicine
181 Longwood Ave
Boston MA 02115
Phone617/525-0997
Fax617/525-0958
vCardDownload vCard (login for email)

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Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
UG3OD023268     (LITONJUA, AUGUSTO A)Sep 21, 2016 - Aug 31, 2018
NIH
Multi-omic approaches to mechanisms of vitamin D, environmental influences, and the microbiome on asthma
Role: Principal Investigator

R01HL111108     (LITONJUA, AUGUSTO A)Feb 1, 2013 - Jan 31, 2017
NIH/NHLBI
Early Life DNA Methylation and Childhood Allergic Disease
Role: Co-Principal Investigator

U01HL091528     (WEISS, SCOTT T)Mar 1, 2009 - Feb 28, 2014
NIH/NHLBI
Randomized Trial: Maternal Vitamin D Supplementation to Prevent Childhood Asthma
Role: Principal Investigator

R01HL091528     (LITONJUA, AUGUSTO A)Dec 1, 2007 - Apr 30, 2019
NIH/NHLBI
RANDOMIZED CONTROLLED TRIAL: VDAART CONTINUATION STUDY - DCC - LEAD
Role: Principal Investigator

R21HL089842     (LITONJUA, AUGUSTO A)Jul 20, 2007 - Jun 30, 2010
NIH/NHLBI
Vitamin D in Obstructive Lung Diseases
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Radder JE, Gregory AD, Leme AS, Cho MH, Chu Y, Kelly NJ, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Beaty TH, Crapo JD, Silverman EK, Zhang Y, Berndt A, Shapiro SD. Variable Susceptibility to Cigarette Smoke-Induced Emphysema in 34 Inbred Strains of Mice Implicates Abi3bp in Emphysema Susceptibility. Am J Respir Cell Mol Biol. 2017 Apr 25. PMID: 28441029.
    View in: PubMed
  2. Farahi N, Paige E, Balla J, Prudence E, Ferreira RC, Southwood M, Appleby SL, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Silverman EK, Cho MH, Danesh J, Paul DS, Freitag DF, Chilvers ER. Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma. Hum Mol Genet. 2017 Apr 15; 26(8):1584-1596. PMID: 28334838.
    View in: PubMed
  3. Lee-Sarwar KA, Bacharier LB, Litonjua AA. Strategies to alter the natural history of childhood asthma. Curr Opin Allergy Clin Immunol. 2017 Apr; 17(2):139-145. PMID: 28079559.
    View in: PubMed
  4. Cardenas A, Rifas-Shiman SL, Agha G, Hivert MF, Litonjua AA, DeMeo DL, Lin X, Amarasiriwardena CJ, Oken E, Gillman MW, Baccarelli AA. Persistent DNA methylation changes associated with prenatal mercury exposure and cognitive performance during childhood. Sci Rep. 2017 Mar 21; 7(1):288. PMID: 28325913.
    View in: PubMed
  5. Wolsk HM, Harshfield BJ, Laranjo N, Carey VJ, O'Connor G, Sandel M, Strunk RC, Bacharier LB, Zeiger RS, Schatz M, Hollis BW, Weiss ST, Litonjua AA. Vitamin D supplementation in pregnancy, prenatal 25(OH)D levels, race, and subsequent asthma or recurrent wheeze in offspring: Secondary analyses from the Vitamin D Antenatal Asthma Reduction Trial. J Allergy Clin Immunol. 2017 Mar 09. PMID: 28285844.
    View in: PubMed
  6. Blomberg M, Rifas-Shiman SL, Camargo CA, Gold DR, Asgari MM, Thyssen JP, Litonjua AA, Gillman MW, Oken E. Low maternal prenatal 25-hydroxy vitamin D blood levels are associated with childhood atopic dermatitis. J Invest Dermatol. 2017 Feb 12. PMID: 28202402.
    View in: PubMed
  7. Busch R, Hobbs BD, Zhou J, Castaldi PJ, McGeachie MJ, Hardin ME, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Agusti A, Make BJ, Crapo JD, Calverley PM, Donner CF, Lomas DA, Wouters EF, Vestbo J, Tal-Singer R, Bakke P, Gulsvik A, Litonjua AA, Sparrow D, Paré PD, Levy RD, Rennard SI, Beaty TH, Hokanson J, Silverman EK, Cho MH. Genetic Association and Risk Scores in a COPD Meta-Analysis of 16,707 Subjects. Am J Respir Cell Mol Biol. 2017 Feb 07. PMID: 28170284.
    View in: PubMed
  8. Hobbs BD, de Jong K, Lamontagne M, Bossé Y, Shrine N, Artigas MS, Wain LV, Hall IP, Jackson VE, Wyss AB, London SJ, North KE, Franceschini N, Strachan DP, Beaty TH, Hokanson JE, Crapo JD, Castaldi PJ, Chase RP, Bartz TM, Heckbert SR, Psaty BM, Gharib SA, Zanen P, Lammers JW, Oudkerk M, Groen HJ, Locantore N, Tal-Singer R, Rennard SI, Vestbo J, Timens W, Paré PD, Latourelle JC, Dupuis J, O'Connor GT, Wilk JB, Kim WJ, Lee MK, Oh YM, Vonk JM, de Koning HJ, Leng S, Belinsky SA, Tesfaigzi Y, Manichaikul A, Wang XQ, Rich SS, Barr RG, Sparrow D, Litonjua AA, Bakke P, Gulsvik A, Lahousse L, Brusselle GG, Stricker BH, Uitterlinden AG, Ampleford EJ, Bleecker ER, Woodruff PG, Meyers DA, Qiao D, Lomas DA, Yim JJ, Kim DK, Hawrylkiewicz I, Sliwinski P, Hardin M, Fingerlin TE, Schwartz DA, Postma DS, MacNee W, Tobin MD, Silverman EK, Boezen HM, Cho MH. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nat Genet. 2017 Mar; 49(3):426-432. PMID: 28166215.
    View in: PubMed
  9. Wain LV, Shrine N, Artigas MS, Erzurumluoglu AM, Noyvert B, Bossini-Castillo L, Obeidat M, Henry AP, Portelli MA, Hall RJ, Billington CK, Rimington TL, Fenech AG, John C, Blake T, Jackson VE, Allen RJ, Prins BP, Campbell A, Porteous DJ, Jarvelin MR, Wielscher M, James AL, Hui J, Wareham NJ, Zhao JH, Wilson JF, Joshi PK, Stubbe B, Rawal R, Schulz H, Imboden M, Probst-Hensch NM, Karrasch S, Gieger C, Deary IJ, Harris SE, Marten J, Rudan I, Enroth S, Gyllensten U, Kerr SM, Polasek O, Kähönen M, Surakka I, Vitart V, Hayward C, Lehtimäki T, Raitakari OT, Evans DM, Henderson AJ, Pennell CE, Wang CA, Sly PD, Wan ES, Busch R, Hobbs BD, Litonjua AA, Sparrow DW, Gulsvik A, Bakke PS, Crapo JD, Beaty TH, Hansel NN, Mathias RA, Ruczinski I, Barnes KC, Bossé Y, Joubert P, van den Berge M, Brandsma CA, Paré PD, Sin DD, Nickle DC, Hao K, Gottesman O, Dewey FE, Bruse SE, Carey DJ, Kirchner HL, Jonsson S, Thorleifsson G, Jonsdottir I, Gislason T, Stefansson K, Schurmann C, Nadkarni G, Bottinger EP, Loos RJ, Walters RG, Chen Z, Millwood IY, Vaucher J, Kurmi OP, Li L, Hansell AL, Brightling C, Zeggini E, Cho MH, Silverman EK, Sayers I, Trynka G, Morris AP, Strachan DP, Hall IP, Tobin MD. Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nat Genet. 2017 Mar; 49(3):416-425. PMID: 28166213.
    View in: PubMed
  10. Forno E, Sordillo J, Brehm J, Chen W, Benos T, Yan Q, Avila L, Soto-Quirós M, Cloutier MM, Colón-Semidey A, Alvarez M, Acosta-Pérez E, Weiss ST, Litonjua AA, Canino G, Celedón JC. Genome-wide interaction study of dust mite allergen on lung function in children with asthma. J Allergy Clin Immunol. 2017 Feb 04. PMID: 28167095.
    View in: PubMed
  11. Forno E, Weiner DJ, Mullen J, Sawicki G, Kurland G, Han YY, Cloutier MM, Canino G, Weiss ST, Litonjua AA, Celedón JC. Obesity and Airway Dysanapsis in Children with and without Asthma. Am J Respir Crit Care Med. 2017 Feb 01; 195(3):314-323. PMID: 27552676.
    View in: PubMed
  12. Litonjua AA, Weiss ST. Vitamin D status through the first 10 years of life: A vital piece of the puzzle in asthma inception. J Allergy Clin Immunol. 2017 Feb; 139(2):459-461. PMID: 27993535.
    View in: PubMed
  13. Agha G, Hajj H, Rifas-Shiman SL, Just AC, Hivert MF, Burris HH, Lin X, Litonjua AA, Oken E, DeMeo DL, Gillman MW, Baccarelli AA. Birth weight-for-gestational age is associated with DNA methylation at birth and in childhood. Clin Epigenetics. 2016; 8:118. PMID: 27891191.
    View in: PubMed
  14. Mirzakhani H, Litonjua AA, McElrath TF, O'Connor G, Lee-Parritz A, Iverson R, Macones G, Strunk RC, Bacharier LB, Zeiger R, Hollis BW, Handy DE, Sharma A, Laranjo N, Carey V, Qiu W, Santolini M, Liu S, Chhabra D, Enquobahrie DA, Williams MA, Loscalzo J, Weiss ST. Early pregnancy vitamin D status and risk of preeclampsia. J Clin Invest. 2016 Dec 01; 126(12):4702-4715. PMID: 27841759.
    View in: PubMed
  15. Sordillo JE, Zhou Y, McGeachie MJ, Ziniti J, Lange N, Laranjo N, Savage JR, Carey V, O'Connor G, Sandel M, Strunk R, Bacharier L, Zeiger R, Weiss ST, Weinstock G, Gold DR, Litonjua AA. Factors influencing the infant gut microbiome at age 3-6 months: Findings from the ethnically diverse Vitamin D Antenatal Asthma Reduction Trial (VDAART). J Allergy Clin Immunol. 2017 Feb; 139(2):482-491.e14. PMID: 27746239.
    View in: PubMed
  16. Al-Garawi A, Carey VJ, Chhabra D, Mirzakhani H, Morrow J, Lasky-Su J, Qiu W, Laranjo N, Litonjua AA, Weiss ST. The Role of Vitamin D in the Transcriptional Program of Human Pregnancy. PLoS One. 2016; 11(10):e0163832. PMID: 27711190.
    View in: PubMed
  17. Weiss ST, Litonjua AA. Can we prevent childhood asthma before birth? Summary of the VDAART results so far. Expert Rev Respir Med. 2016 Oct; 10(10):1039-40. PMID: 27564842.
    View in: PubMed
  18. Litonjua AA. Acetaminophen and Asthma--A Small Sigh of Relief? N Engl J Med. 2016 Aug 18; 375(7):684-5. PMID: 27532835.
    View in: PubMed
  19. Joung KE, Burris HH, Van Marter LJ, McElrath TF, Michael Z, Tabatabai P, Litonjua AA, Weiss ST, Christou H. Vitamin D and bronchopulmonary dysplasia in preterm infants. J Perinatol. 2016 Oct; 36(10):878-82. PMID: 27467562.
    View in: PubMed
  20. Litonjua AA, Weiss ST. Prenatal Vitamin D and Offspring Wheezing--Reply. JAMA. 2016 Jun 28; 315(24):2731. PMID: 27367772.
    View in: PubMed
  21. Tse SM, Rifas-Shiman SL, Coull BA, Litonjua AA, Oken E, Gold DR. Sex-specific risk factors for childhood wheeze and longitudinal phenotypes of wheeze. J Allergy Clin Immunol. 2016 Dec; 138(6):1561-1568.e6. PMID: 27246527.
    View in: PubMed
  22. Rice MB, Rifas-Shiman SL, Litonjua AA, Oken E, Gillman MW, Kloog I, Luttmann-Gibson H, Zanobetti A, Coull BA, Schwartz J, Koutrakis P, Mittleman MA, Gold DR. Lifetime Exposure to Ambient Pollution and Lung Function in Children. Am J Respir Crit Care Med. 2016 Apr 15; 193(8):881-8. PMID: 26575800; PMCID: PMC4849180 [Available on 04/15/17].
  23. Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu CJ, Küpers LK, Oh SS, Hoyo C, Gruzieva O, Söderhäll C, Salas LA, Baïz N, Zhang H, Lepeule J, Ruiz C, Ligthart S, Wang T, Taylor JA, Duijts L, Sharp GC, Jankipersadsing SA, Nilsen RM, Vaez A, Fallin MD, Hu D, Litonjua AA, Fuemmeler BF, Huen K, Kere J, Kull I, Munthe-Kaas MC, Gehring U, Bustamante M, Saurel-Coubizolles MJ, Quraishi BM, Ren J, Tost J, Gonzalez JR, Peters MJ, Håberg SE, Xu Z, van Meurs JB, Gaunt TR, Kerkhof M, Corpeleijn E, Feinberg AP, Eng C, Baccarelli AA, Benjamin Neelon SE, Bradman A, Merid SK, Bergström A, Herceg Z, Hernandez-Vargas H, Brunekreef B, Pinart M, Heude B, Ewart S, Yao J, Lemonnier N, Franco OH, Wu MC, Hofman A, McArdle W, Van der Vlies P, Falahi F, Gillman MW, Barcellos LF, Kumar A, Wickman M, Guerra S, Charles MA, Holloway J, Auffray C, Tiemeier HW, Smith GD, Postma D, Hivert MF, Eskenazi B, Vrijheid M, Arshad H, Antó JM, Dehghan A, Karmaus W, Annesi-Maesano I, Sunyer J, Ghantous A, Pershagen G, Holland N, Murphy SK, DeMeo DL, Burchard EG, Ladd-Acosta C, Snieder H, Nystad W, Koppelman GH, Relton CL, Jaddoe VW, Wilcox A, Melén E, London SJ. DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis. Am J Hum Genet. 2016 Apr 07; 98(4):680-96. PMID: 27040690; PMCID: PMC4833289 [Available on 10/07/16].
  24. Bunyavanich S, Rifas-Shiman SL, Platts-Mills TA, Workman L, Sordillo JE, Camargo CA, Gillman MW, Gold DR, Litonjua AA. Prenatal, perinatal, and childhood vitamin D exposure and their association with childhood allergic rhinitis and allergic sensitization. J Allergy Clin Immunol. 2016 Apr; 137(4):1063-70.e1-2. PMID: 26874366; PMCID: PMC4826831 [Available on 04/01/17].
  25. McGeachie MJ, Sordillo JE, Gibson T, Weinstock GM, Liu YY, Gold DR, Weiss ST, Litonjua A. Longitudinal Prediction of the Infant Gut Microbiome with Dynamic Bayesian Networks. Sci Rep. 2016 Feb 08; 6:20359. PMID: 26853461; PMCID: PMC4745046.
  26. Blatter J, Brehm JM, Sordillo J, Forno E, Boutaoui N, Acosta-Pérez E, Alvarez M, Colón-Semidey A, Weiss ST, Litonjua AA, Canino G, Celedón JC. Folate Deficiency, Atopy, and Severe Asthma Exacerbations in Puerto Rican Children. Ann Am Thorac Soc. 2016 Feb; 13(2):223-30. PMID: 26561879; PMCID: PMC5015712 [Available on 02/01/17].
  27. Litonjua AA, Carey VJ, Laranjo N, Harshfield BJ, McElrath TF, O'Connor GT, Sandel M, Iverson RE, Lee-Paritz A, Strunk RC, Bacharier LB, Macones GA, Zeiger RS, Schatz M, Hollis BW, Hornsby E, Hawrylowicz C, Wu AC, Weiss ST. Effect of Prenatal Supplementation With Vitamin D on Asthma or Recurrent Wheezing in Offspring by Age 3 Years: The VDAART Randomized Clinical Trial. JAMA. 2016 Jan 26; 315(4):362-70. PMID: 26813209.
    View in: PubMed
  28. Mehta AJ, Cassidy A, Litonjua AA, Sparrow D, Vokonas P, Schwartz J. Dietary anthocyanin intake and age-related decline in lung function: longitudinal findings from the VA Normative Aging Study. Am J Clin Nutr. 2016 Feb; 103(2):542-50. PMID: 26791184; PMCID: PMC4733262.
  29. Gold DR, Litonjua AA, Carey VJ, Manson JE, Buring JE, Lee IM, Gordon D, Walter J, Friedenberg G, Hankinson JL, Copeland T, Luttmann-Gibson H. Lung VITAL: Rationale, design, and baseline characteristics of an ancillary study evaluating the effects of vitamin D and/or marine omega-3 fatty acid supplements on acute exacerbations of chronic respiratory disease, asthma control, pneumonia and lung function in adults. Contemp Clin Trials. 2016 Mar; 47:185-95. PMID: 26784651; PMCID: PMC4818187 [Available on 03/01/17].
  30. Litonjua AA, Gold DR. Early-Life Exposures and Later Lung Function. Add Pollutants to the Mix. Am J Respir Crit Care Med. 2016 Jan 15; 193(2):110-1. PMID: 26771413.
    View in: PubMed
  31. Brehm JM, Man Tse S, Croteau-Chonka DC, Forno E, Litonjua AA, Raby BA, Chen W, Yan Q, Boutaoui N, Acosta-Pérez E, Avila L, Weiss ST, Soto-Quiros M, Cloutier MM, Hu D, Pino-Yanes M, Wenzel SE, Spear ML, Kolls JK, Burchard EG, Canino G, Celedón JC. A Genome-Wide Association Study of Post-bronchodilator Lung Function in Children with Asthma. Am J Respir Crit Care Med. 2015 Sep 01; 192(5):634-7. PMID: 26325155; PMCID: PMC4595689.
  32. Han YY, Forno E, Brehm JM, Acosta-Pérez E, Alvarez M, Colón-Semidey A, Rivera-Soto W, Campos H, Litonjua AA, Alcorn JF, Canino G, Celedón JC. Diet, interleukin-17, and childhood asthma in Puerto Ricans. Ann Allergy Asthma Immunol. 2015 Oct; 115(4):288-293.e1. PMID: 26319606; PMCID: PMC4721241 [Available on 10/01/16].
  33. Hansel NN, Paré PD, Rafaels N, Sin DD, Sandford A, Daley D, Vergara C, Huang L, Elliott WM, Pascoe CD, Arsenault BA, Postma DS, Boezen HM, Bossé Y, van den Berge M, Hiemstra PS, Cho MH, Litonjua AA, Sparrow D, Ober C, Wise RA, Connett J, Neptune ER, Beaty TH, Ruczinski I, Mathias RA, Barnes KC. Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2015 Aug; 53(2):226-34. PMID: 25514360; PMCID: PMC4566043 [Available on 08/01/16].
  34. Himes BE, Koziol-White C, Johnson M, Nikolos C, Jester W, Klanderman B, Litonjua AA, Tantisira KG, Truskowski K, MacDonald K, Panettieri RA, Weiss ST. Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma. PLoS One. 2015; 10(7):e0134057. PMID: 26207385; PMCID: PMC4514847.
  35. Weiss ST, Litonjua AA. Vitamin D dosing for infectious and immune disorders. Thorax. 2015 Oct; 70(10):919-20. PMID: 26138735.
    View in: PubMed
  36. Brehm JM, Ramratnam SK, Tse SM, Croteau-Chonka DC, Pino-Yanes M, Rosas-Salazar C, Litonjua AA, Raby BA, Boutaoui N, Han YY, Chen W, Forno E, Marsland AL, Nugent NR, Eng C, Colón-Semidey A, Alvarez M, Acosta-Pérez E, Spear ML, Martinez FD, Avila L, Weiss ST, Soto-Quiros M, Ober C, Nicolae DL, Barnes KC, Lemanske RF, Strunk RC, Liu A, London SJ, Gilliland F, Sleiman P, March M, Hakonarson H, Duan QL, Kolls JK, Fritz GK, Hu D, Fani N, Stevens JS, Almli LM, Burchard EG, Shin J, McQuaid EL, Ressler K, Canino G, Celedón JC. Stress and Bronchodilator Response in Children with Asthma. Am J Respir Crit Care Med. 2015 Jul 01; 192(1):47-56. PMID: 25918834; PMCID: PMC4511425 [Available on 07/01/16].
  37. Dahlin A, Litonjua A, Lima JJ, Tamari M, Kubo M, Irvin CG, Peters SP, Tantisira KG. Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma. PLoS One. 2015; 10(6):e0129385. PMID: 26083242; PMCID: PMC4470685.
  38. Quraishi SA, Litonjua AA, Elias KM, Gibbons FK, Giovannucci E, Camargo CA, Christopher KB. Association between pre-hospital vitamin D status and hospital-acquired new-onset delirium. Br J Nutr. 2015 Jun 14; 113(11):1753-60. PMID: 26067807; PMCID: PMC4634007.
  39. Thickett DR, Moromizato T, Litonjua AA, Amrein K, Quraishi SA, Lee-Sarwar KA, Mogensen KM, Purtle SW, Gibbons FK, Camargo CA, Giovannucci E, Christopher KB. Association between prehospital vitamin D status and incident acute respiratory failure in critically ill patients: a retrospective cohort study. BMJ Open Respir Res. 2015; 2(1):e000074. PMID: 26113982; PMCID: PMC4477148.
  40. Dahlin A, Litonjua A, Irvin CG, Peters SP, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genome-wide association study of leukotriene modifier response in asthma. Pharmacogenomics J. 2016 Apr; 16(2):151-7. PMID: 26031901; PMCID: PMC4668236.
  41. Clemmer GL, Wu AC, Rosner B, McGeachie MJ, Litonjua AA, Tantisira KG, Weiss ST. Measuring the corticosteroid responsiveness endophenotype in asthmatic patients. J Allergy Clin Immunol. 2015 Aug; 136(2):274-81.e8. PMID: 25951964; PMCID: PMC4530065.
  42. Sordillo JE, Kelly R, Bunyavanich S, McGeachie M, Qiu W, Croteau-Chonka DC, Soto-Quiros M, Avila L, Celedón JC, Brehm JM, Weiss ST, Gold DR, Litonjua AA. Genome-wide expression profiles identify potential targets for gene-environment interactions in asthma severity. J Allergy Clin Immunol. 2015 Oct; 136(4):885-92.e2. PMID: 25913104; PMCID: PMC4763940.
  43. Amrein K, Litonjua AA, Moromizato T, Quraishi SA, Gibbons FK, Pieber TR, Camargo CA, Giovannucci E, Christopher KB. Increases in pre-hospitalization serum 25(OH)D concentrations are associated with improved 30-day mortality after hospital admission: A cohort study. Clin Nutr. 2016 Apr; 35(2):514-21. PMID: 25935851.
    View in: PubMed
  44. Weiss ST, Litonjua AA. Vitamin D, the gut microbiome, and the hygiene hypothesis. How does asthma begin? Am J Respir Crit Care Med. 2015 Mar 01; 191(5):492-3. PMID: 25723818; PMCID: PMC4384774.
  45. Hanson C, Lyden E, Furtado J, Campos H, Sparrow D, Vokonas P, Litonjua AA. Serum tocopherol levels and vitamin E intake are associated with lung function in the normative aging study. Clin Nutr. 2016 Feb; 35(1):169-74. PMID: 25715694; PMCID: PMC4529394 [Available on 02/01/17].
  46. Mirzakhani H, Al-Garawi A, Weiss ST, Litonjua AA. Vitamin D and the development of allergic disease: how important is it? Clin Exp Allergy. 2015 Jan; 45(1):114-25. PMID: 25307157; PMCID: PMC4369152 [Available on 01/01/16].
  47. Sordillo JE, Scirica CV, Rifas-Shiman SL, Gillman MW, Bunyavanich S, Camargo CA, Weiss ST, Gold DR, Litonjua AA. Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children. J Allergy Clin Immunol. 2015 Feb; 135(2):441-8. PMID: 25441647; PMCID: PMC4323723.
  48. Lepeule J, Litonjua AA, Coull B, Koutrakis P, Sparrow D, Vokonas PS, Schwartz J. Long-term effects of traffic particles on lung function decline in the elderly. Am J Respir Crit Care Med. 2014 Sep 01; 190(5):542-8. PMID: 25028775; PMCID: PMC4214085.
  49. Bunyavanich S, Rifas-Shiman SL, Platts-Mills TA, Workman L, Sordillo JE, Gillman MW, Gold DR, Litonjua AA. Peanut allergy prevalence among school-age children in a US cohort not selected for any disease. J Allergy Clin Immunol. 2014 Sep; 134(3):753-5. PMID: 25086866; PMCID: PMC4149917.
  50. Weiss ST, Litonjua AA. Maternal antibiotic use and childhood asthma: the missing link? Lancet Respir Med. 2014 Aug; 2(8):597-8. PMID: 25066333.
    View in: PubMed
  51. Rice MB, Rifas-Shiman SL, Oken E, Gillman MW, Ljungman PL, Litonjua AA, Schwartz J, Coull BA, Zanobetti A, Koutrakis P, Melly SJ, Mittleman MA, Gold DR. Exposure to traffic and early life respiratory infection: A cohort study. Pediatr Pulmonol. 2014 Mar 27. PMID: 24678045.
    View in: PubMed
  52. Oken E, Baccarelli AA, Gold DR, Kleinman KP, Litonjua AA, De Meo D, Rich-Edwards JW, Rifas-Shiman SL, Sagiv S, Taveras EM, Weiss ST, Belfort MB, Burris HH, Camargo CA, Huh SY, Mantzoros C, Parker MG, Gillman MW. Cohort profile: project viva. Int J Epidemiol. 2015 Feb; 44(1):37-48. PMID: 24639442; PMCID: PMC4339753.
  53. Savage JH, Matsui EC, McCormack M, Litonjua AA, Wood RA, Keet CA. The association between asthma and allergic disease and mortality: a 30-year follow-up study. J Allergy Clin Immunol. 2014 May; 133(5):1484-7, 1487.e1-5. PMID: 24636085; PMCID: PMC4006089.
  54. Litonjua AA, Lange NE, Carey VJ, Brown S, Laranjo N, Harshfield BJ, O'Connor GT, Sandel M, Strunk RC, Bacharier LB, Zeiger RS, Schatz M, Hollis BW, Weiss ST. The Vitamin D Antenatal Asthma Reduction Trial (VDAART): rationale, design, and methods of a randomized, controlled trial of vitamin D supplementation in pregnancy for the primary prevention of asthma and allergies in children. Contemp Clin Trials. 2014 May; 38(1):37-50. PMID: 24614387; PMCID: PMC4086903.
  55. Lepeule J, Bind MA, Baccarelli AA, Koutrakis P, Tarantini L, Litonjua A, Sparrow D, Vokonas P, Schwartz JD. Epigenetic influences on associations between air pollutants and lung function in elderly men: the normative aging study. Environ Health Perspect. 2014 Jun; 122(6):566-72. PMID: 24602767; PMCID: PMC4050500.
  56. Burris HH, Rifas-Shiman SL, Huh SY, Kleinman K, Litonjua AA, Oken E, Rich-Edwards JW, Camargo CA, Gillman MW. Vitamin D status and hypertensive disorders in pregnancy. Ann Epidemiol. 2014 May; 24(5):399-403.e1. PMID: 24631523; PMCID: PMC4011985.
  57. Bunyavanich S, Rifas-Shiman SL, Platts-Mills TA, Workman L, Sordillo JE, Camargo CA, Gillman MW, Gold DR, Litonjua AA. Peanut, milk, and wheat intake during pregnancy is associated with reduced allergy and asthma in children. J Allergy Clin Immunol. 2014 May; 133(5):1373-82. PMID: 24522094; PMCID: PMC4004710.
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  125. Zhu ZZ, Sparrow D, Hou L, Tarantini L, Bollati V, Litonjua AA, Zanobetti A, Vokonas P, Wright RO, Baccarelli A, Schwartz J. Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study. Cancer Causes Control. 2011 Mar; 22(3):437-47. PMID: 21188491; PMCID: PMC3752839.
  126. Li F, Peng M, Jiang L, Sun Q, Zhang K, Lian F, Litonjua AA, Gao J, Gao X. Vitamin D deficiency is associated with decreased lung function in Chinese adults with asthma. Respiration. 2011; 81(6):469-75. PMID: 21124013; PMCID: PMC3124457.
  127. Baccarelli A, Wright R, Bollati V, Litonjua A, Zanobetti A, Tarantini L, Sparrow D, Vokonas P, Schwartz J. Ischemic heart disease and stroke in relation to blood DNA methylation. Epidemiology. 2010 Nov; 21(6):819-28. PMID: 20805753; PMCID: PMC3690659.
  128. Duan QL, Gaume BR, Hawkins GA, Himes BE, Bleecker ER, Klanderman B, Irvin CG, Peters SP, Meyers DA, Hanrahan JP, Lima JJ, Litonjua AA, Tantisira KG, Liggett SB. Regulatory haplotypes in ARG1 are associated with altered bronchodilator response. Am J Respir Crit Care Med. 2011 Feb 15; 183(4):449-54. PMID: 20851928; PMCID: PMC3056223.
  129. Sørheim IC, DeMeo DL, Washko G, Litonjua A, Sparrow D, Bowler R, Bakke P, Pillai SG, Coxson HO, Lomas DA, Silverman EK, Hersh CP. Polymorphisms in the superoxide dismutase-3 gene are associated with emphysema in COPD. COPD. 2010 Aug; 7(4):262-8. PMID: 20673035; PMCID: PMC2923920.
  130. Lange NE, Rifas-Shiman SL, Camargo CA, Gold DR, Gillman MW, Litonjua AA. Maternal dietary pattern during pregnancy is not associated with recurrent wheeze in children. J Allergy Clin Immunol. 2010 Aug; 126(2):250-5, 255.e1-4. PMID: 20584543; PMCID: PMC2917539.
  131. Wu AC, Lasky-Su J, Rogers CA, Klanderman BJ, Litonjua AA. Fungal exposure modulates the effect of polymorphisms of chitinases on emergency department visits and hospitalizations. Am J Respir Crit Care Med. 2010 Oct 01; 182(7):884-9. PMID: 20538957; PMCID: PMC2970860.
  132. Brehm JM, Schuemann B, Fuhlbrigge AL, Hollis BW, Strunk RC, Zeiger RS, Weiss ST, Litonjua AA. Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. J Allergy Clin Immunol. 2010 Jul; 126(1):52-8.e5. PMID: 20538327; PMCID: PMC2902692.
  133. Hersh CP, Pillai SG, Zhu G, Lomas DA, Bakke P, Gulsvik A, DeMeo DL, Klanderman BJ, Lazarus R, Litonjua AA, Sparrow D, Reilly JJ, Agusti A, Calverley PM, Donner CF, Levy RD, Make BJ, Paré PD, Rennard SI, Vestbo J, Wouters EF, Scholand MB, Coon H, Hoidal J, Silverman EK. Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. Am J Respir Crit Care Med. 2010 Sep 01; 182(5):605-13. PMID: 20463177; PMCID: PMC2937234.
  134. Foreman MG, Kong X, DeMeo DL, Pillai SG, Hersh CP, Bakke P, Gulsvik A, Lomas DA, Litonjua AA, Shapiro SD, Tal-Singer R, Silverman EK. Polymorphisms in surfactant protein-D are associated with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2011 Mar; 44(3):316-22. PMID: 20448057; PMCID: PMC3095932.
  135. Sordillo JE, Hoffman EB, Celedón JC, Litonjua AA, Milton DK, Gold DR. Multiple microbial exposures in the home may protect against asthma or allergy in childhood. Clin Exp Allergy. 2010 Jun; 40(6):902-10. PMID: 20412140; PMCID: PMC3730840.
  136. Baccarelli A, Tarantini L, Wright RO, Bollati V, Litonjua AA, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J. Repetitive element DNA methylation and circulating endothelial and inflammation markers in the VA normative aging study. Epigenetics. 2010 Apr; 5(3):222-8. PMID: 20305373.
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  138. Cho MH, Boutaoui N, Klanderman BJ, Sylvia JS, Ziniti JP, Hersh CP, DeMeo DL, Hunninghake GM, Litonjua AA, Sparrow D, Lange C, Won S, Murphy JR, Beaty TH, Regan EA, Make BJ, Hokanson JE, Crapo JD, Kong X, Anderson WH, Tal-Singer R, Lomas DA, Bakke P, Gulsvik A, Pillai SG, Silverman EK. Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet. 2010 Mar; 42(3):200-2. PMID: 20173748; PMCID: PMC2828499.
  139. Wu AC, Himes BE, Lasky-Su J, Litonjua A, Li L, Lange C, Lima J, Irvin CG, Weiss ST. Development of a Pharmacogenetic Predictive Test in asthma: proof of concept. Pharmacogenet Genomics. 2010 Feb; 20(2):86-93. PMID: 20032818; PMCID: PMC3654515.
  140. Litonjua AA, Gong L, Duan QL, Shin J, Moore MJ, Weiss ST, Johnson JA, Klein TE, Altman RB. Very important pharmacogene summary ADRB2. Pharmacogenet Genomics. 2010 Jan; 20(1):64-9. PMID: 19927042; PMCID: PMC3098753.
  141. Hunninghake GM, Cho MH, Tesfaigzi Y, Soto-Quiros ME, Avila L, Lasky-Su J, Stidley C, Melén E, Söderhäll C, Hallberg J, Kull I, Kere J, Svartengren M, Pershagen G, Wickman M, Lange C, Demeo DL, Hersh CP, Klanderman BJ, Raby BA, Sparrow D, Shapiro SD, Silverman EK, Litonjua AA, Weiss ST, Celedón JC. MMP12, lung function, and COPD in high-risk populations. N Engl J Med. 2009 Dec 31; 361(27):2599-608. PMID: 20018959; PMCID: PMC2904064.
  142. Lange NE, Litonjua A, Hawrylowicz CM, Weiss S. Vitamin D, the immune system and asthma. Expert Rev Clin Immunol. 2009 Nov; 5(6):693-702. PMID: 20161622.
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  143. DeMeo DL, Mariani T, Bhattacharya S, Srisuma S, Lange C, Litonjua A, Bueno R, Pillai SG, Lomas DA, Sparrow D, Shapiro SD, Criner GJ, Kim HP, Chen Z, Choi AM, Reilly J, Silverman EK. Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet. 2009 Oct; 85(4):493-502. PMID: 19800047; PMCID: PMC2756547.
  144. Litonjua AA, Murphy A. Replication of genes for asthma: the importance of well-designed studies. Clin Exp Allergy. 2009 Oct; 39(10):1453-5. PMID: 19954426.
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  145. Himes BE, Wu AC, Duan QL, Klanderman B, Litonjua AA, Tantisira K, Ramoni MF, Weiss ST. Predicting response to short-acting bronchodilator medication using Bayesian networks. Pharmacogenomics. 2009 Sep; 10(9):1393-412. PMID: 19761364; PMCID: PMC2804237.
  146. Rogers AJ, Tantisira KG, Fuhlbrigge AL, Litonjua AA, Lasky-Su JA, Szefler SJ, Strunk RC, Zeiger RS, Weiss ST. Predictors of poor response during asthma therapy differ with definition of outcome. Pharmacogenomics. 2009 Aug; 10(8):1231-42. PMID: 19663668; PMCID: PMC2746392.
  147. Sakurai R, Shin E, Fonseca S, Sakurai T, Litonjua AA, Weiss ST, Torday JS, Rehan VK. 1alpha,25(OH)2D3 and its 3-epimer promote rat lung alveolar epithelial-mesenchymal interactions and inhibit lipofibroblast apoptosis. Am J Physiol Lung Cell Mol Physiol. 2009 Sep; 297(3):L496-505. PMID: 19574420; PMCID: PMC2739775.
  148. Litonjua AA. Childhood asthma may be a consequence of vitamin D deficiency. Curr Opin Allergy Clin Immunol. 2009 Jun; 9(3):202-7. PMID: 19365260; PMCID: PMC2897155.
  149. He JQ, Foreman MG, Shumansky K, Zhang X, Akhabir L, Sin DD, Man SF, DeMeo DL, Litonjua AA, Silverman EK, Connett JE, Anthonisen NR, Wise RA, Paré PD, Sandford AJ. Associations of IL6 polymorphisms with lung function decline and COPD. Thorax. 2009 Aug; 64(8):698-704. PMID: 19359268; PMCID: PMC2859187.
  150. Wilker EH, Alexeeff SE, Poon A, Litonjua AA, Sparrow D, Vokonas PS, Mittleman MA, Schwartz J. Candidate genes for respiratory disease associated with markers of inflammation and endothelial dysfunction in elderly men. Atherosclerosis. 2009 Oct; 206(2):480-5. PMID: 19409562; PMCID: PMC2882878.
  151. Wilker E, Mittleman MA, Litonjua AA, Poon A, Baccarelli A, Suh H, Wright RO, Sparrow D, Vokonas P, Schwartz J. Postural changes in blood pressure associated with interactions between candidate genes for chronic respiratory diseases and exposure to particulate matter. Environ Health Perspect. 2009 Jun; 117(6):935-40. PMID: 19590686; PMCID: PMC2702409.
  152. Brehm JM, Celedón JC, Soto-Quiros ME, Avila L, Hunninghake GM, Forno E, Laskey D, Sylvia JS, Hollis BW, Weiss ST, Litonjua AA. Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica. Am J Respir Crit Care Med. 2009 May 01; 179(9):765-71. PMID: 19179486; PMCID: PMC2675563.
  153. Baccarelli A, Wright RO, Bollati V, Tarantini L, Litonjua AA, Suh HH, Zanobetti A, Sparrow D, Vokonas PS, Schwartz J. Rapid DNA methylation changes after exposure to traffic particles. Am J Respir Crit Care Med. 2009 Apr 01; 179(7):572-8. PMID: 19136372; PMCID: PMC2720123.
  154. Hersh CP, Hansel NN, Barnes KC, Lomas DA, Pillai SG, Coxson HO, Mathias RA, Rafaels NM, Wise RA, Connett JE, Klanderman BJ, Jacobson FL, Gill R, Litonjua AA, Sparrow D, Reilly JJ, Silverman EK. Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema. Am J Respir Cell Mol Biol. 2009 Sep; 41(3):324-31. PMID: 19131638; PMCID: PMC2742752.
  155. Murphy A, Lasky-Su J, Tantisira KG, Litonjua AA, Lange C, Weiss ST. Genome-wide association studies of family data in pharmacogenetics: a case study. Curr Pharm Des. 2009; 15(32):3764-72. PMID: 19925427.
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  156. Wu AC, Gillman MW, Taveras EM, Litonjua AA. INSIG2 is Associated with Lower Gain in Weight-for-Length Between Birth and Age 6 Months. Clin Med Pediatr. 2009; 3:33-37. PMID: 20354568.
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  157. Cho MH, Klanderman BJ, Litonjua AA, Sparrow D, Silverman EK, Raby BA. Folliculin mutations are not associated with severe COPD. BMC Med Genet. 2008 Dec 30; 9:120. PMID: 19116017; PMCID: PMC2636779.
  158. Bollati V, Schwartz J, Wright R, Litonjua A, Tarantini L, Suh H, Sparrow D, Vokonas P, Baccarelli A. Decline in genomic DNA methylation through aging in a cohort of elderly subjects. Mech Ageing Dev. 2009 Apr; 130(4):234-9. PMID: 19150625; PMCID: PMC2956267.
  159. Cho MH, Ciulla DM, Klanderman BJ, Hersh CP, Litonjua AA, Sparrow D, Raby BA, Silverman EK. Analysis of exonic elastin variants in severe, early-onset chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2009 Jun; 40(6):751-5. PMID: 19029017; PMCID: PMC2689920.
  160. Sharma S, Litonjua AA, Tantisira KG, Fuhlbrigge AL, Szefler SJ, Strunk RC, Zeiger RS, Murphy AJ, Weiss ST. Clinical predictors and outcomes of consistent bronchodilator response in the childhood asthma management program. J Allergy Clin Immunol. 2008 Nov; 122(5):921-928.e4. PMID: 18848350; PMCID: PMC2947830.
  161. Forno E, Onderdonk AB, McCracken J, Litonjua AA, Laskey D, Delaney ML, Dubois AM, Gold DR, Ryan LM, Weiss ST, Celedón JC. Diversity of the gut microbiota and eczema in early life. Clin Mol Allergy. 2008 Sep 22; 6:11. PMID: 18808715; PMCID: PMC2562383.
  162. Chuang KJ, Coull BA, Zanobetti A, Suh H, Schwartz J, Stone PH, Litonjua A, Speizer FE, Gold DR. Particulate air pollution as a risk factor for ST-segment depression in patients with coronary artery disease. Circulation. 2008 Sep 23; 118(13):1314-20. PMID: 18779445; PMCID: PMC2751595.
  163. Lampe BJ, Park SK, Robins T, Mukherjee B, Litonjua AA, Amarasiriwardena C, Weisskopf M, Sparrow D, Hu H. Association between 24-hour urinary cadmium and pulmonary function among community-exposed men: the VA Normative Aging Study. Environ Health Perspect. 2008 Sep; 116(9):1226-30. PMID: 18795167; PMCID: PMC2535626.
  164. Litonjua AA. Dietary factors and the development of asthma. Immunol Allergy Clin North Am. 2008 Aug; 28(3):603-29, ix. PMID: 18572110; PMCID: PMC2536613.
  165. Tantisira KG, Lazarus R, Litonjua AA, Klanderman B, Weiss ST. Chromosome 17: association of a large inversion polymorphism with corticosteroid response in asthma. Pharmacogenet Genomics. 2008 Aug; 18(8):733-7. PMID: 18622266; PMCID: PMC3225071.
  166. Litonjua AA, Lasky-Su J, Schneiter K, Tantisira KG, Lazarus R, Klanderman B, Lima JJ, Irvin CG, Peters SP, Hanrahan JP, Liggett SB, Hawkins GA, Meyers DA, Bleecker ER, Lange C, Weiss ST. ARG1 is a novel bronchodilator response gene: screening and replication in four asthma cohorts. Am J Respir Crit Care Med. 2008 Oct 01; 178(7):688-94. PMID: 18617639; PMCID: PMC2556451.
  167. Alexeeff SE, Litonjua AA, Wright RO, Baccarelli A, Suh H, Sparrow D, Vokonas PS, Schwartz J. Ozone exposure, antioxidant genes, and lung function in an elderly cohort: VA normative aging study. Occup Environ Med. 2008 Nov; 65(11):736-42. PMID: 18524839; PMCID: PMC2575239.
  168. Taveras EM, Rifas-Shiman SL, Camargo CA, Gold DR, Litonjua AA, Oken E, Weiss ST, Gillman MW. Higher adiposity in infancy associated with recurrent wheeze in a prospective cohort of children. J Allergy Clin Immunol. 2008 May; 121(5):1161-1166.e3. PMID: 18466784; PMCID: PMC3253368.
  169. Poon AH, Tantisira KG, Litonjua AA, Lazarus R, Xu J, Lasky-Su J, Lima JJ, Irvin CG, Hanrahan JP, Lange C, Weiss ST. Association of corticotropin-releasing hormone receptor-2 genetic variants with acute bronchodilator response in asthma. Pharmacogenet Genomics. 2008 May; 18(5):373-82. PMID: 18408560; PMCID: PMC3208318.
  170. Litonjua AA, Gold DR. Asthma and obesity: common early-life influences in the inception of disease. J Allergy Clin Immunol. 2008 May; 121(5):1075-84; quiz 1085-6. PMID: 18378287.
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  171. Baccarelli A, Cassano PA, Litonjua A, Park SK, Suh H, Sparrow D, Vokonas P, Schwartz J. Cardiac autonomic dysfunction: effects from particulate air pollution and protection by dietary methyl nutrients and metabolic polymorphisms. Circulation. 2008 Apr 08; 117(14):1802-9. PMID: 18378616; PMCID: PMC3093965.
  172. Weiss ST, Litonjua AA. Childhood asthma is a fat-soluble vitamin deficiency disease. Clin Exp Allergy. 2008 Mar; 38(3):385-7. PMID: 18177489.
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  173. Perlstein T, Weuve J, Schwartz J, Sparrow D, Wright R, Litonjua A, Nie H, Hu H. Cumulative community-level lead exposure and pulse pressure: the normative aging study. Environ Health Perspect. 2007 Dec; 115(12):1696-700. PMID: 18087585; PMCID: PMC2137129.
  174. Tantisira KG, Silverman ES, Mariani TJ, Xu J, Richter BG, Klanderman BJ, Litonjua AA, Lazarus R, Rosenwasser LJ, Fuhlbrigge AL, Weiss ST. FCER2: a pharmacogenetic basis for severe exacerbations in children with asthma. J Allergy Clin Immunol. 2007 Dec; 120(6):1285-91. PMID: 17980418.
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  175. Chahine T, Baccarelli A, Litonjua A, Wright RO, Suh H, Gold DR, Sparrow D, Vokonas P, Schwartz J. Particulate air pollution, oxidative stress genes, and heart rate variability in an elderly cohort. Environ Health Perspect. 2007 Nov; 115(11):1617-22. PMID: 18007994; PMCID: PMC2072834.
  176. Litonjua AA, Weiss ST. Is vitamin D deficiency to blame for the asthma epidemic? J Allergy Clin Immunol. 2007 Nov; 120(5):1031-5. PMID: 17919705.
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  177. Alexeeff SE, Litonjua AA, Suh H, Sparrow D, Vokonas PS, Schwartz J. Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA normative aging study. Chest. 2007 Dec; 132(6):1890-7. PMID: 17925423.
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  178. Platts-Mills TA, Satinover SM, Naccara L, Litonjua AA, Phipatanakul W, Carter MC, Heymann PW, Woodfolk JA, Peters EJ, Gold DR. Prevalence and titer of IgE antibodies to mouse allergens. J Allergy Clin Immunol. 2007 Nov; 120(5):1058-64. PMID: 17767949.
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  179. Weiss ST, Litonjua AA. Maternal diet vs lack of exposure to sunlight as the cause of the epidemic of asthma, allergies and other autoimmune diseases. Thorax. 2007 Sep; 62(9):746-8. PMID: 17726168; PMCID: PMC2117306.
  180. Alexeeff SE, Litonjua AA, Sparrow D, Vokonas PS, Schwartz J. Statin use reduces decline in lung function: VA Normative Aging Study. Am J Respir Crit Care Med. 2007 Oct 15; 176(8):742-7. PMID: 17673694; PMCID: PMC2020828.
  181. Phipatanakul W, Litonjua AA, Platts-Mills TA, Naccara LM, Celedón JC, Abdulkerim H, Hoffman EB, Gold DR. Sensitization to mouse allergen and asthma and asthma morbidity among women in Boston. J Allergy Clin Immunol. 2007 Oct; 120(4):954-6. PMID: 17590423; PMCID: PMC2243261.
  182. Celedón JC, Milton DK, Ramsey CD, Litonjua AA, Ryan L, Platts-Mills TA, Gold DR. Exposure to dust mite allergen and endotoxin in early life and asthma and atopy in childhood. J Allergy Clin Immunol. 2007 Jul; 120(1):144-9. PMID: 17507083; PMCID: PMC3737770.
  183. DeMeo DL, Hersh CP, Hoffman EA, Litonjua AA, Lazarus R, Sparrow D, Benditt JO, Criner G, Make B, Martinez FJ, Scanlon PD, Sciurba FC, Utz JP, Reilly JJ, Silverman EK. Genetic determinants of emphysema distribution in the national emphysema treatment trial. Am J Respir Crit Care Med. 2007 Jul 01; 176(1):42-8. PMID: 17363767; PMCID: PMC2049064.
  184. Camargo CA, Rifas-Shiman SL, Litonjua AA, Rich-Edwards JW, Weiss ST, Gold DR, Kleinman K, Gillman MW. Maternal intake of vitamin D during pregnancy and risk of recurrent wheeze in children at 3 y of age. Am J Clin Nutr. 2007 Mar; 85(3):788-95. PMID: 17344501; PMCID: PMC4406411.
  185. Devereux G, Litonjua AA, Turner SW, Craig LC, McNeill G, Martindale S, Helms PJ, Seaton A, Weiss ST. Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr. 2007 Mar; 85(3):853-9. PMID: 17344509.
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  186. Ly NP, Rifas-Shiman SL, Litonjua AA, Tzianabos AO, Schaub B, Ruiz-Pérez B, Tantisira KG, Finn PW, Gillman MW, Weiss ST, Gold DR. Cord blood cytokines and acute lower respiratory illnesses in the first year of life. Pediatrics. 2007 Jan; 119(1):e171-8. PMID: 17145902; PMCID: PMC1994927.
  187. Hersh CP, DeMeo DL, Raby BA, Litonjua AA, Sylvia JS, Sparrow D, Reilly JJ, Silverman EK. Genetic linkage and association analysis of COPD-related traits on chromosome 8p. COPD. 2006 Dec; 3(4):189-94. PMID: 17361499.
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  188. Ramsey CD, Gold DR, Litonjua AA, Sredl DL, Ryan L, Celedón JC. Respiratory illnesses in early life and asthma and atopy in childhood. J Allergy Clin Immunol. 2007 Jan; 119(1):150-6. PMID: 17208596.
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  189. Perlstein TS, Gumieniak O, Williams GH, Sparrow D, Vokonas PS, Gaziano M, Weiss ST, Litonjua AA. Uric acid and the development of hypertension: the normative aging study. Hypertension. 2006 Dec; 48(6):1031-6. PMID: 17060508.
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  190. Scirica CV, Gold DR, Ryan L, Abulkerim H, Celedón JC, Platts-Mills TA, Naccara LM, Weiss ST, Litonjua AA. Predictors of cord blood IgE levels in children at risk for asthma and atopy. J Allergy Clin Immunol. 2007 Jan; 119(1):81-8. PMID: 17208588.
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  191. Litonjua AA, Rifas-Shiman SL, Ly NP, Tantisira KG, Rich-Edwards JW, Camargo CA, Weiss ST, Gillman MW, Gold DR. Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 y of age. Am J Clin Nutr. 2006 Oct; 84(4):903-11. PMID: 17023719; PMCID: PMC1994925.
  192. Ly NP, Ruiz-Pérez B, Onderdonk AB, Tzianabos AO, Litonjua AA, Liang C, Laskey D, Delaney ML, DuBois AM, Levy H, Gold DR, Ryan LM, Weiss ST, Celedón JC. Mode of delivery and cord blood cytokines: a birth cohort study. Clin Mol Allergy. 2006 Sep 26; 4:13. PMID: 17002791; PMCID: PMC1592116.
  193. DeMeo D, Mariani T, Lange C, Lake S, Litonjua A, Celedón J, Reilly J, Chapman HA, Sparrow D, Spira A, Beane J, Pinto-Plata V, Speizer FE, Shapiro S, Weiss ST, Silverman EK. The SERPINE2 gene is associated with chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2006 Aug; 3(6):502. PMID: 16921128.
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  194. McGraw DW, Fogel KM, Kong S, Litonjua AA, Kranias EG, Aronow BJ, Liggett SB. Transcriptional response to persistent beta2-adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility. Physiol Genomics. 2006 Oct 11; 27(2):171-7. PMID: 16849635.
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  195. Tepas EC, Litonjua AA, Celedón JC, Sredl D, Gold DR. Sensitization to aeroallergens and airway hyperresponsiveness at 7 years of age. Chest. 2006 Jun; 129(6):1500-8. PMID: 16778267.
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  196. Weiss ST, Litonjua AA, Lange C, Lazarus R, Liggett SB, Bleecker ER, Tantisira KG. Overview of the pharmacogenetics of asthma treatment. Pharmacogenomics J. 2006 Sep-Oct; 6(5):311-26. PMID: 16568148.
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  197. Willwerth BM, Schaub B, Tantisira KG, Gold DR, Palmer LJ, Litonjua AA, Perkins DL, Schroeter C, Gibbons FK, Gillman MW, Weiss ST, Finn PW. Prenatal, perinatal, and heritable influences on cord blood immune responses. Ann Allergy Asthma Immunol. 2006 Mar; 96(3):445-53. PMID: 16597079; PMCID: PMC1562525.
  198. Litonjua AA. The significance of beta2-adrenergic receptor polymorphisms in asthma. Curr Opin Pulm Med. 2006 Jan; 12(1):12-7. PMID: 16357573.
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  199. Demeo DL, Mariani TJ, Lange C, Srisuma S, Litonjua AA, Celedon JC, Lake SL, Reilly JJ, Chapman HA, Mecham BH, Haley KJ, Sylvia JS, Sparrow D, Spira AE, Beane J, Pinto-Plata V, Speizer FE, Shapiro SD, Weiss ST, Silverman EK. The SERPINE2 gene is associated with chronic obstructive pulmonary disease. Am J Hum Genet. 2006 Feb; 78(2):253-64. PMID: 16358219; PMCID: PMC1380249.
  200. Pfeiffer RM, Ryan L, Litonjua A, Pee D. A case-cohort design for assessing covariate effects in longitudinal studies. Biometrics. 2005 Dec; 61(4):982-91. PMID: 16401271.
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  201. Raby BA, Hwang ES, Van Steen K, Tantisira K, Peng S, Litonjua A, Lazarus R, Giallourakis C, Rioux JD, Sparrow D, Silverman EK, Glimcher LH, Weiss ST. T-bet polymorphisms are associated with asthma and airway hyperresponsiveness. Am J Respir Crit Care Med. 2006 Jan 01; 173(1):64-70. PMID: 16179640; PMCID: PMC2662983.
  202. Kelleher CM, Silverman EK, Broekelmann T, Litonjua AA, Hernandez M, Sylvia JS, Stoler J, Reilly JJ, Chapman HA, Speizer FE, Weiss ST, Mecham RP, Raby BA. A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2005 Oct; 33(4):355-62. PMID: 16081882; PMCID: PMC2715343.
  203. Lim U, Peng K, Shane B, Stover PJ, Litonjua AA, Weiss ST, Gaziano JM, Strawderman RL, Raiszadeh F, Selhub J, Tucker KL, Cassano PA. Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. J Nutr. 2005 Aug; 135(8):1989-94. PMID: 16046727.
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  204. Gold DR, Litonjua AA, Zanobetti A, Coull BA, Schwartz J, MacCallum G, Verrier RL, Nearing BD, Canner MJ, Suh H, Stone PH. Air pollution and ST-segment depression in elderly subjects. Environ Health Perspect. 2005 Jul; 113(7):883-7. PMID: 16002377; PMCID: PMC1257650.
  205. Schaub B, Tantisira KG, Gibbons FK, He H, Litonjua AA, Gillman MW, Weiss S, Perkins DL, Gold DR, Finn PW. Fetal cord blood: aspects of heightened immune responses. J Clin Immunol. 2005 Jul; 25(4):329-37. PMID: 16133989; PMCID: PMC1488727.
  206. Raby BA, Van Steen K, Celedón JC, Litonjua AA, Lange C, Weiss ST. Paternal history of asthma and airway responsiveness in children with asthma. Am J Respir Crit Care Med. 2005 Sep 01; 172(5):552-8. PMID: 15937295; PMCID: PMC2718530.
  207. Litonjua AA, Tantisira KG, Lake S, Lazarus R, Richter BG, Gabriel S, Silverman ES, Weiss ST. Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma. Respir Res. 2005 Jun 03; 6:52. PMID: 15935090; PMCID: PMC1180474.
  208. Schwartz J, Litonjua A, Suh H, Verrier M, Zanobetti A, Syring M, Nearing B, Verrier R, Stone P, MacCallum G, Speizer FE, Gold DR. Traffic related pollution and heart rate variability in a panel of elderly subjects. Thorax. 2005 Jun; 60(6):455-61. PMID: 15923244; PMCID: PMC1747419.
  209. Tantisira KG, Small KM, Litonjua AA, Weiss ST, Liggett SB. Molecular properties and pharmacogenetics of a polymorphism of adenylyl cyclase type 9 in asthma: interaction between beta-agonist and corticosteroid pathways. Hum Mol Genet. 2005 Jun 15; 14(12):1671-7. PMID: 15879435.
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  210. Litonjua AA, Belanger K, Celedón JC, Milton DK, Bracken MB, Kraft P, Triche EW, Sredl DL, Weiss ST, Leaderer BP, Gold DR. Polymorphisms in the 5' region of the CD14 gene are associated with eczema in young children. J Allergy Clin Immunol. 2005 May; 115(5):1056-62. PMID: 15867866.
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  211. Litonjua AA, Lazarus R, Sparrow D, Demolles D, Weiss ST. Lung function in type 2 diabetes: the Normative Aging Study. Respir Med. 2005 Dec; 99(12):1583-90. PMID: 16291079.
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  212. Hersh CP, Demeo DL, Lange C, Litonjua AA, Reilly JJ, Kwiatkowski D, Laird N, Sylvia JS, Sparrow D, Speizer FE, Weiss ST, Silverman EK. Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations. Am J Respir Cell Mol Biol. 2005 Jul; 33(1):71-8. PMID: 15817713; PMCID: PMC2715305.
  213. Litonjua AA, Celedón JC, Hausmann J, Nikolov M, Sredl D, Ryan L, Platts-Mills TA, Weiss ST, Gold DR. Variation in total and specific IgE: effects of ethnicity and socioeconomic status. J Allergy Clin Immunol. 2005 Apr; 115(4):751-7. PMID: 15805994.
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  214. Raby BA, Celedón JC, Litonjua AA, Phipatanakul W, Sredl D, Oken E, Ryan L, Weiss ST, Gold DR. Low-normal gestational age as a predictor of asthma at 6 years of age. Pediatrics. 2004 Sep; 114(3):e327-32. PMID: 15342893.
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  215. Litonjua AA, Silverman EK, Tantisira KG, Sparrow D, Sylvia JS, Weiss ST. Beta 2-adrenergic receptor polymorphisms and haplotypes are associated with airways hyperresponsiveness among nonsmoking men. Chest. 2004 Jul; 126(1):66-74. PMID: 15249444.
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  216. Phipatanakul W, Celedón JC, Raby BA, Litonjua AA, Milton DK, Sredl D, Weiss ST, Gold DR. Endotoxin exposure and eczema in the first year of life. Pediatrics. 2004 Jul; 114(1):13-8. PMID: 15231902; PMCID: PMC1242194.
  217. Celedón JC, Lange C, Raby BA, Litonjua AA, Palmer LJ, DeMeo DL, Reilly JJ, Kwiatkowski DJ, Chapman HA, Laird N, Sylvia JS, Hernandez M, Speizer FE, Weiss ST, Silverman EK. The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Hum Mol Genet. 2004 Aug 01; 13(15):1649-56. PMID: 15175276.
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  218. DeMeo DL, Zanobetti A, Litonjua AA, Coull BA, Schwartz J, Gold DR. Ambient air pollution and oxygen saturation. Am J Respir Crit Care Med. 2004 Aug 15; 170(4):383-7. PMID: 15142869.
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  219. Tantisira KG, Litonjua AA, Weiss ST, Fuhlbrigge AL. Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP). Thorax. 2003 Dec; 58(12):1036-41. PMID: 14645968; PMCID: PMC1746552.
  220. Litonjua AA, Sparrow D, Guevarra L, O'Connor GT, Weiss ST, Tollerud DJ. Serum interferon-gamma is associated with longitudinal decline in lung function among asthmatic patients: the Normative Aging Study. Ann Allergy Asthma Immunol. 2003 Apr; 90(4):422-8. PMID: 12722965.
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  221. Tsunoda M, Litonjua AA, Kuniak MP, Weiss ST, Satoh T, Guevarra L, Tollerud DJ. Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women. Int Arch Allergy Immunol. 2003 Feb; 130(2):158-64. PMID: 12673070.
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  222. Celedón JC, Litonjua AA, Ryan L, Weiss ST, Gold DR. Bottle feeding in the bed or crib before sleep time and wheezing in early childhood. Pediatrics. 2002 Dec; 110(6):e77. PMID: 12456944.
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  223. Celedon JC, Wright RJ, Litonjua AA, Sredl D, Ryan L, Weiss ST, Gold DR. Day care attendance in early life, maternal history of asthma, and asthma at the age of 6 years. Am J Respir Crit Care Med. 2003 May 01; 167(9):1239-43. PMID: 12446273.
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  224. Litonjua AA, Milton DK, Celedon JC, Ryan L, Weiss ST, Gold DR. A longitudinal analysis of wheezing in young children: the independent effects of early life exposure to house dust endotoxin, allergens, and pets. J Allergy Clin Immunol. 2002 Nov; 110(5):736-42. PMID: 12417882.
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  225. Celedón JC, Litonjua AA, Ryan L, Platts-Mills T, Weiss ST, Gold DR. Exposure to cat allergen, maternal history of asthma, and wheezing in first 5 years of life. Lancet. 2002 Sep 07; 360(9335):781-2. PMID: 12241839.
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  226. Litonjua AA, Sparrow D, Celedon JC, DeMolles D, Weiss ST. Association of body mass index with the development of methacholine airway hyperresponsiveness in men: the Normative Aging Study. Thorax. 2002 Jul; 57(7):581-5. PMID: 12096199; PMCID: PMC1746377.
  227. Celedón JC, Litonjua AA, Ryan L, Weiss ST, Gold DR. Lack of association between antibiotic use in the first year of life and asthma, allergic rhinitis, or eczema at age 5 years. Am J Respir Crit Care Med. 2002 Jul 01; 166(1):72-5. PMID: 12091174.
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  228. Celedón JC, Litonjua AA, Ryan L, Weiss ST, Gold DR. Day care attendance, respiratory tract illnesses, wheezing, asthma, and total serum IgE level in early childhood. Arch Pediatr Adolesc Med. 2002 Mar; 156(3):241-5. PMID: 11876667.
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  229. Celedón JC, Palmer LJ, Litonjua AA, Weiss ST, Wang B, Fang Z, Xu X. Body mass index and asthma in adults in families of subjects with asthma in Anqing, China. Am J Respir Crit Care Med. 2001 Nov 15; 164(10 Pt 1):1835-40. PMID: 11734432.
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  230. Litonjua AA, Carey VJ, Burge HA, Weiss ST, Gold DR. Exposure to cockroach allergen in the home is associated with incident doctor-diagnosed asthma and recurrent wheezing. J Allergy Clin Immunol. 2001 Jan; 107(1):41-7. PMID: 11149989.
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  231. Gold DR, Litonjua A, Schwartz J, Lovett E, Larson A, Nearing B, Allen G, Verrier M, Cherry R, Verrier R. Ambient pollution and heart rate variability. Circulation. 2000 Mar 21; 101(11):1267-73. PMID: 10725286.
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  232. Litonjua AA, Carey VJ, Weiss ST, Gold DR. Race, socioeconomic factors, and area of residence are associated with asthma prevalence. Pediatr Pulmonol. 1999 Dec; 28(6):394-401. PMID: 10587412.
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  233. Celedon JC, Litonjua AA, Weiss ST, Gold DR. Day care attendance in the first year of life and illnesses of the upper and lower respiratory tract in children with a familial history of atopy. Pediatrics. 1999 Sep; 104(3 Pt 1):495-500. PMID: 10469775.
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  234. Litonjua AA, Sparrow D, Weiss ST. The FEF25-75/FVC ratio is associated with methacholine airway responsiveness. The normative aging study. Am J Respir Crit Care Med. 1999 May; 159(5 Pt 1):1574-9. PMID: 10228129.
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  235. Litonjua AA, Carey VJ, Burge HA, Weiss ST, Gold DR. Parental history and the risk for childhood asthma. Does mother confer more risk than father? Am J Respir Crit Care Med. 1998 Jul; 158(1):176-81. PMID: 9655726.
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  236. Litonjua AA, Sparrow D, Weiss ST, O'Connor GT, Long AA, Ohman JL. Sensitization to cat allergen is associated with asthma in older men and predicts new-onset airway hyperresponsiveness. The Normative Aging Study. Am J Respir Crit Care Med. 1997 Jul; 156(1):23-7. PMID: 9230721.
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  237. Lim FC, Chavez F, Jamora E, Litonjua A. Clinical trial of beclomethasone dipropionate in Filipino asthmatics. Postgrad Med J. 1975; 51 Suppl 4:49-50. PMID: 1197193.
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