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Malgorzata Borowiak

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Borowiak M, Küllmer F, Gegenfurtner F, Peil S, Nasufovic V, Zahler S, Thorn-Seshold O, Trauner D, Arndt HD. Optical Manipulation of F-Actin with Photoswitchable Small Molecules. J Am Chem Soc. 2020 May 20; 142(20):9240-9249. PMID: 32388980.
    Citations:    
  2. Scavuzzo MA, Borowiak M. Two drugs converged in a pancreatic ß cell. Sci Transl Med. 2020 Feb 12; 12(530). PMID: 32051228.
    Citations:    
  3. Bettini M, Scavuzzo MA, Liu B, Kolawole E, Guo L, Evavold BD, Borowiak M, Bettini ML. A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells. Diabetes. 2020 Mar; 69(3):392-400. PMID: 31836691.
    Citations:    
  4. Scavuzzo MA, Chmielowiec J, Yang D, Wamble K, Chaboub LS, Duraine L, Tepe B, Glasgow SM, Arenkiel BR, Brou C, Deneen B, Borowiak M. Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA. Cell Rep. 2018 12 26; 25(13):3811-3827.e7. PMID: 30590051.
    Citations:    Fields:    
  5. Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M. Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 08 22; 9(1):3356. PMID: 30135482.
    Citations:    Fields:    Translation:AnimalsCells
  6. Scavuzzo MA, Teaw J, Yang D, Borowiak M. Generation of Scaffold-free, Three-dimensional Insulin Expressing Pancreatoids from Mouse Pancreatic Progenitors In Vitro. J Vis Exp. 2018 06 02; (136). PMID: 29912186.
    Citations:    Fields:    Translation:AnimalsCells
  7. Fiorini F, Robin JP, Kanaan J, Borowiak M, Croquette V, Le Hir H, Jalinot P, Mocquet V. HTLV-1 Tax plugs and freezes UPF1 helicase leading to nonsense-mediated mRNA decay inhibition. Nat Commun. 2018 01 30; 9(1):431. PMID: 29382845.
    Citations:    Fields:    Translation:HumansCells
  8. Sprouse ML, Scavuzzo MA, Blum S, Shevchenko I, Lee T, Makedonas G, Borowiak M, Bettini ML, Bettini M. High self-reactivity drives T-bet and potentiates Treg function in tissue-specific autoimmunity. JCI Insight. 2018 01 25; 3(2). PMID: 29367462.
    Citations: 3     Fields:    
  9. Sprouse ML, Shevchenko I, Scavuzzo MA, Joseph F, Lee T, Blum S, Borowiak M, Bettini ML, Bettini M. Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity. J Immunol. 2018 02 01; 200(3):909-914. PMID: 29282307.
    Citations: 1     Fields:    Translation:AnimalsCells
  10. Barzi M, Pankowicz FP, Zorman B, Liu X, Legras X, Yang D, Borowiak M, Bissig-Choisat B, Sumazin P, Li F, Bissig KD. Erratum: A novel humanized mouse lacking murine p450 oxidoreductase for studying human drug metabolism. Nat Commun. 2017 10 17; 8(1):984. PMID: 29042563.
    Citations: 1     Fields:    
  11. Scavuzzo MA, Yang D, Borowiak M. Organotypic pancreatoids with native mesenchyme develop Insulin producing endocrine cells. Sci Rep. 2017 09 07; 7(1):10810. PMID: 28883507.
    Citations: 1     Fields:    
  12. Barzi M, Pankowicz FP, Zorman B, Liu X, Legras X, Yang D, Borowiak M, Bissig-Choisat B, Sumazin P, Li F, Bissig KD. A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism. Nat Commun. 2017 06 28; 8(1):39. PMID: 28659616.
    Citations: 2     Fields:    Translation:HumansAnimals
  13. Ku AT, Shaver TM, Rao AS, Howard JM, Rodriguez CN, Miao Q, Garcia G, Le D, Yang D, Borowiak M, Cohen DN, Chitsazzadeh V, Diwan AH, Tsai KY, Nguyen H. TCF7L1 promotes skin tumorigenesis independently of ß-catenin through induction of LCN2. Elife. 2017 05 03; 6. PMID: 28467300.
    Citations: 2     Fields:    Translation:HumansAnimals
  14. Scavuzzo MA, Borowiak M. Editing genetics, stem cells are prophetic, what's the best way to model cells of diabetics? Stem Cell Investig. 2016; 3:81. PMID: 28066783.
    Citations:    
  15. Pankowicz FP, Barzi M, Legras X, Hubert L, Mi T, Tomolonis JA, Ravishankar M, Sun Q, Yang D, Borowiak M, Sumazin P, Elsea SH, Bissig-Choisat B, Bissig KD. Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia. Nat Commun. 2016 08 30; 7:12642. PMID: 27572891.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  16. Bissig-Choisat B, Kettlun-Leyton C, Legras XD, Zorman B, Barzi M, Chen LL, Amin MD, Huang YH, Pautler RG, Hampton OA, Prakash MM, Yang D, Borowiak M, Muzny D, Doddapaneni HV, Hu J, Shi Y, Gaber MW, Hicks MJ, Thompson PA, Lu Y, Mills GB, Finegold M, Goss JA, Parsons DW, Vasudevan SA, Sumazin P, López-Terrada D, Bissig KD. Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer. J Hepatol. 2016 08; 65(2):325-33. PMID: 27117591.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  17. Yang D, Scavuzzo MA, Chmielowiec J, Sharp R, Bajic A, Borowiak M. Enrichment of G2/M cell cycle phase in human pluripotent stem cells enhances HDR-mediated gene repair with customizable endonucleases. Sci Rep. 2016 Feb 18; 6:21264. PMID: 26887909.
    Citations: 14     Fields:    Translation:HumansCells
  18. Borowiak M, Nahaboo W, Reynders M, Nekolla K, Jalinot P, Hasserodt J, Rehberg M, Delattre M, Zahler S, Vollmar A, Trauner D, Thorn-Seshold O. Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death. Cell. 2015 Jul 16; 162(2):403-411. PMID: 26165941.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  19. Larocque É, André-Arpin C, Borowiak M, Lemay G, Switzer WM, Duc Dodon M, Mesnard JM, Barbeau B. Human T-cell leukemia virus type 3 (HTLV-3) and HTLV-4 antisense-transcript-encoded proteins interact and transactivate Jun family-dependent transcription via their atypical bZIP motif. J Virol. 2014 Aug; 88(16):8956-70. PMID: 24872589.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  20. Chmielowiec J, Borowiak M. In vitro differentiation and expansion of human pluripotent stem cell-derived pancreatic progenitors. Rev Diabet Stud. 2014; 11(1):19-34. PMID: 25148365.
    Citations:    Fields:    Translation:HumansAnimalsCells
  21. Borowiak M, Grobelna B, Synak A, Bojarski P, Kubicki AA. Time-resolved emission spectra of 4-dimethylamino-4'-cyano-stilbene and resveratrol in high viscosity solvents and silica matrices. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov; 115:111-7. PMID: 23832219.
    Citations:    Fields:    
  22. Borowiak M, Kuhlmann AS, Girard S, Gazzolo L, Mesnard JM, Jalinot P, Dodon MD. HTLV-1 bZIP factor impedes the menin tumor suppressor and upregulates JunD-mediated transcription of the hTERT gene. Carcinogenesis. 2013 Nov; 34(11):2664-72. PMID: 23784080.
    Citations: 10     Fields:    Translation:HumansCells
  23. Chen AE, Borowiak M, Sherwood RI, Kweudjeu A, Melton DA. Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation. Development. 2013 Feb 01; 140(3):675-86. PMID: 23293299.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  24. Sneddon JB, Borowiak M, Melton DA. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme. Nature. 2012 Nov 29; 491(7426):765-8. PMID: 23041930.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  25. Borowiak M. The new generation of beta-cells: replication, stem cell differentiation, and the role of small molecules. Rev Diabet Stud. 2010; 7(2):93-104. PMID: 21060968.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  26. Borowiak M, Melton DA. How to make beta cells? Curr Opin Cell Biol. 2009 Dec; 21(6):727-32. PMID: 19781928.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  27. Reynard O, Borowiak M, Volchkova VA, Delpeut S, Mateo M, Volchkov VE. Ebolavirus glycoprotein GP masks both its own epitopes and the presence of cellular surface proteins. J Virol. 2009 Sep; 83(18):9596-601. PMID: 19587051.
    Citations: 34     Fields:    Translation:HumansCells
  28. Marx-Stoelting P, Borowiak M, Knorpp T, Birchmeier C, Buchmann A, Schwarz M. Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c-Met. Int J Cancer. 2009 Apr 15; 124(8):1767-72. PMID: 19123478.
    Citations: 7     Fields:    Translation:AnimalsCells
  29. Borowiak M, Maehr R, Chen S, Chen AE, Tang W, Fox JL, Schreiber SL, Melton DA. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell. 2009 Apr 03; 4(4):348-58. PMID: 19341624.
    Citations: 145     Fields:    Translation:HumansAnimalsCells
  30. Chen S, Borowiak M, Fox JL, Maehr R, Osafune K, Davidow L, Lam K, Peng LF, Schreiber SL, Rubin LL, Melton D. A small molecule that directs differentiation of human ESCs into the pancreatic lineage. Nat Chem Biol. 2009 Apr; 5(4):258-65. PMID: 19287398.
    Citations: 155     Fields:    Translation:HumansAnimalsCells
  31. Giebeler A, Boekschoten MV, Klein C, Borowiak M, Birchmeier C, Gassler N, Wasmuth HE, Müller M, Trautwein C, Streetz KL. c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile duct ligation in mice. Gastroenterology. 2009 Jul; 137(1):297-308, 308.e1-4. PMID: 19208365.
    Citations: 20     Fields:    Translation:AnimalsCells
  32. Osafune K, Caron L, Borowiak M, Martinez RJ, Fitz-Gerald CS, Sato Y, Cowan CA, Chien KR, Melton DA. Marked differences in differentiation propensity among human embryonic stem cell lines. Nat Biotechnol. 2008 Mar; 26(3):313-5. PMID: 18278034.
    Citations: 275     Fields:    Translation:HumansCells
  33. Chmielowiec J, Borowiak M, Morkel M, Stradal T, Munz B, Werner S, Wehland J, Birchmeier C, Birchmeier W. c-Met is essential for wound healing in the skin. J Cell Biol. 2007 Apr 09; 177(1):151-62. PMID: 17403932.
    Citations: 95     Fields:    Translation:AnimalsCells
  34. Borowiak M, Garratt AN, Wüstefeld T, Strehle M, Trautwein C, Birchmeier C. Met provides essential signals for liver regeneration. Proc Natl Acad Sci U S A. 2004 Jul 20; 101(29):10608-13. PMID: 15249655.
    Citations: 138     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.