Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Patricia A. D'Amore, Ph.D.

Other Positions

Available: 09/01/18, Expires: 09/30/20

The projects uses cell biological, biochemical and molecular techniques as well as animal models to understand the steps leading to the development of age-related macular degeneration. The focus is on the role of lipids andinflammation.

Troglitazone Prevents Oxidized LDL-induced RPE Dysfunction by Suppressing Inflammatory Pathways
Full Time/Year Long, 06/01/16 - 08/31/16

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R13EY029583 (D'AMORE, PATRICIA ANN) Aug 5, 2018 - Jul 31, 2019
    Fifth International Biennial Symposium on Age-related Macular Degeneration (AMD)
    Role: Principal Investigator
  2. R01EY026539 (D'AMORE, PATRICIA ANN) Feb 1, 2017 - Jan 31, 2020
    Investigation of endomucin as a novel regulator of angiogenesis
    Role: Principal Investigator
  3. R13EY027181 (D'AMORE, PATRICIA ANN) Aug 1, 2016 - Jul 31, 2017
    Fourth Biennial AMD Symposium
    Role: Principal Investigator
  4. R13EY024813 (D'AMORE, PATRICIA ANN) Aug 1, 2014 - Jul 31, 2015
    Third Biennial Symposium on Age Related Macular Degeneration
    Role: Principal Investigator
  5. S10RR027992 (D'AMORE, PATRICIA ANN) May 1, 2011 - Apr 30, 2012
    Transmission Electron Microscope
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yang J, LeBlanc ME, Cano I, Saez-Torres KL, Saint-Geniez M, Ng YS, D'Amore PA. ADAM10 and ADAM17 proteases mediate proinflammatory cytokine-induced and constitutive cleavage of endomucin from the endothelial surface. J Biol Chem. 2020 May 08; 295(19):6641-6651. PMID: 32193206.
  2. LeBlanc ME, Saez-Torres KL, Cano I, Hu Z, Saint-Geniez M, Ng YS, D'Amore PA. Glycocalyx regulation of vascular endothelial growth factor receptor 2 activity. FASEB J. 2019 08; 33(8):9362-9373. PMID: 31141406.
  3. Park-Windhol C, Ng YS, Yang J, Primo V, Saint-Geniez M, D'Amore PA. Endomucin inhibits VEGF-induced endothelial cell migration, growth, and morphogenesis by modulating VEGFR2 signaling. Sci Rep. 2017 12 07; 7(1):17138. PMID: 29215001.
    Citations: 3     Fields:    
  4. Wu W, Duan Y, Ma G, Zhou G, Park-Windhol C, D'Amore PA, Lei H. AAV-CRISPR/Cas9-Mediated Depletion of VEGFR2 Blocks Angiogenesis In Vitro. Invest Ophthalmol Vis Sci. 2017 12 01; 58(14):6082-6090. PMID: 29204648.
    Citations: 2     Fields:    Translation:HumansCells
  5. Zhou G, Duan Y, Ma G, Wu W, Hu Z, Chen N, Chee Y, Cui J, Samad A, Matsubara JA, Mukai S, D'Amore PA, Lei H. Introduction of the MDM2 T309G Mutation in Primary Human Retinal Epithelial Cells Enhances Experimental Proliferative Vitreoretinopathy. Invest Ophthalmol Vis Sci. 2017 10 01; 58(12):5361-5367. PMID: 29049737.
    Citations:    Fields:    Translation:HumansAnimalsCells
  6. Huang X, Zhou G, Wu W, Duan Y, Ma G, Song J, Xiao R, Vandenberghe L, Zhang F, D'Amore PA, Lei H. Genome editing abrogates angiogenesis in vivo. Nat Commun. 2017 07 24; 8(1):112. PMID: 28740073.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  7. Machuca-Parra AI, Bigger-Allen AA, Sanchez AV, Boutabla A, Cardona-Vélez J, Amarnani D, Saint-Geniez M, Siebel CW, Kim LA, D'Amore PA, Arboleda-Velasquez JF. Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL. J Exp Med. 2017 Aug 07; 214(8):2271-2282. PMID: 28698285.
    Citations:    Fields:    Translation:AnimalsCells
  8. Wu W, Tang L, D'Amore PA, Lei H. Application of CRISPR-Cas9 in eye disease. Exp Eye Res. 2017 08; 161:116-123. PMID: 28619505.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  9. Lam JD, Oh DJ, Wong LL, Amarnani D, Park-Windhol C, Sanchez AV, Cardona-Velez J, McGuone D, Stemmer-Rachamimov AO, Eliott D, Bielenberg DR, van Zyl T, Shen L, Gai X, D'Amore PA, Kim LA, Arboleda-Velasquez JF. Identification of RUNX1 as a Mediator of Aberrant Retinal Angiogenesis. Diabetes. 2017 07; 66(7):1950-1956. PMID: 28400392.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  10. Huang X, Zhou G, Wu W, Ma G, D'Amore PA, Mukai S, Lei H. Editing VEGFR2 Blocks VEGF-Induced Activation of Akt and Tube Formation. Invest Ophthalmol Vis Sci. 2017 02 01; 58(2):1228-1236. PMID: 28241310.
    Citations: 5     Fields:    Translation:HumansCells
  11. Gnanaguru G, Choi AR, Amarnani D, D'Amore PA. Oxidized Lipoprotein Uptake Through the CD36 Receptor Activates the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells. Invest Ophthalmol Vis Sci. 2016 09 01; 57(11):4704-12. PMID: 27607416.
    Citations: 5     Fields:    Translation:HumansCells
  12. Wong LL, Lee NG, Amarnani D, Choi CJ, Bielenberg DR, Freitag SK, D'Amore PA, Kim LA. Orbital Angiogenesis and Lymphangiogenesis in Thyroid Eye Disease: An Analysis of Vascular Growth Factors with Clinical Correlation. Ophthalmology. 2016 09; 123(9):2028-36. PMID: 27423310.
    Citations: 1     Fields:    Translation:Humans
  13. Ma G, Duan Y, Huang X, Qian CX, Chee Y, Mukai S, Cui J, Samad A, Matsubara JA, Kazlauskas A, D'Amore PA, Gu S, Lei H. Prevention of Proliferative Vitreoretinopathy by Suppression of Phosphatidylinositol 5-Phosphate 4-Kinases. Invest Ophthalmol Vis Sci. 2016 07 01; 57(8):3935-43. PMID: 27472081.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  14. Duan Y, Ma G, Huang X, D'Amore PA, Zhang F, Lei H. The Clustered, Regularly Interspaced, Short Palindromic Repeats-associated Endonuclease 9 (CRISPR/Cas9)-created MDM2 T309G Mutation Enhances Vitreous-induced Expression of MDM2 and Proliferation and Survival of Cells. J Biol Chem. 2016 07 29; 291(31):16339-47. PMID: 27246850.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  15. Kim CB, D'Amore PA, Connor KM. Revisiting the mouse model of oxygen-induced retinopathy. Eye Brain. 2016; 8:67-79. PMID: 27499653.
    Citations: 6     
  16. Primo V, Graham M, Bigger-Allen AA, Chick JM, Ospina C, Quiroz YT, Manent J, Gygi SP, Lopera F, D'Amore PA, Arboleda-Velasquez JF. Blood biomarkers in a mouse model of CADASIL. Brain Res. 2016 08 01; 1644:118-26. PMID: 27174004.
    Citations: 2     Fields:    Translation:HumansAnimals
  17. Park-Windhol C, D'Amore PA. Disorders of Vascular Permeability. Annu Rev Pathol. 2016 05 23; 11:251-81. PMID: 26907525.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  18. Shahrabi-Farahani S, Gallottini M, Martins F, Li E, Mudge DR, Nakayama H, Hida K, Panigrahy D, D'Amore PA, Bielenberg DR. Neuropilin 1 Receptor Is Up-Regulated in Dysplastic Epithelium and Oral Squamous Cell Carcinoma. Am J Pathol. 2016 Apr; 186(4):1055-64. PMID: 26877262.
    Citations: 2     Fields:    Translation:HumansCells
  19. Zahr A, Alcaide P, Yang J, Jones A, Gregory M, dela Paz NG, Patel-Hett S, Nevers T, Koirala A, Luscinskas FW, Saint-Geniez M, Ksander B, D'Amore PA, Argüeso P. Endomucin prevents leukocyte-endothelial cell adhesion and has a critical role under resting and inflammatory conditions. Nat Commun. 2016 Feb 02; 7:10363. PMID: 26831939.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  20. Sánchez-Palencia DM, Bigger-Allen A, Saint-Geniez M, Arboleda-Velásquez JF, D'Amore PA. Coculture Assays for Endothelial Cells-Mural Cells Interactions. Methods Mol Biol. 2016; 1464:35-47. PMID: 27858354.
    Citations:    Fields:    Translation:HumansAnimalsCells
  21. Kim LA, Wong LL, Amarnani DS, Bigger-Allen AA, Hu Y, Marko CK, Eliott D, Shah VA, McGuone D, Stemmer-Rachamimov AO, Gai X, D'Amore PA, Arboleda-Velasquez JF. Characterization of cells from patient-derived fibrovascular membranes in proliferative diabetic retinopathy. Mol Vis. 2015; 21:673-87. PMID: 26120272.
    Citations: 4     Fields:    Translation:HumansCells
  22. Arboleda-Velasquez JF, Valdez CN, Marko CK, D'Amore PA. From pathobiology to the targeting of pericytes for the treatment of diabetic retinopathy. Curr Diab Rep. 2015 Feb; 15(2):573. PMID: 25620405.
    Citations: 8     Fields:    Translation:HumansCells
  23. Bielenberg DR, D'Amore PA. Lymphatics in development and pathology: introduction to a special issue of Microvascular Research. Microvasc Res. 2014 Nov; 96:1-2. PMID: 25200924.
    Citations:    Fields:    Translation:HumansAnimals
  24. Panigrahy D, Adini I, Mamluk R, Levonyak N, Bruns CJ, D'Amore PA, Klagsbrun M, Bielenberg DR. Regulation of soluble neuropilin 1, an endogenous angiogenesis inhibitor, in liver development and regeneration. Pathology. 2014 Aug; 46(5):416-23. PMID: 24977735.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  25. Valdez CN, Arboleda-Velasquez JF, Amarnani DS, Kim LA, D'Amore PA. Retinal microangiopathy in a mouse model of inducible mural cell loss. Am J Pathol. 2014 Oct; 184(10):2618-26. PMID: 25092275.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  26. Arboleda-Velasquez JF, Primo V, Graham M, James A, Manent J, D'Amore PA. Notch signaling functions in retinal pericyte survival. Invest Ophthalmol Vis Sci. 2014 Jul 11; 55(8):5191-9. PMID: 25015359.
    Citations: 8     Fields:    Translation:AnimalsCells
  27. Kim LA, Amarnani D, Gnanaguru G, Tseng WA, Vavvas DG, D'Amore PA. Tamoxifen toxicity in cultured retinal pigment epithelial cells is mediated by concurrent regulated cell death mechanisms. Invest Ophthalmol Vis Sci. 2014 Jul 03; 55(8):4747-58. PMID: 24994868.
    Citations: 8     Fields:    Translation:HumansCells
  28. Shahrabi-Farahani S, Wang L, Zwaans BM, Santana JM, Shimizu A, Takashima S, Kreuter M, Coultas L, D'Amore PA, Arbeit JM, Akslen LA, Bielenberg DR. Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas. Lab Invest. 2014 Jul; 94(7):752-65. PMID: 24791743.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  29. Walshe TE, dela Paz NG, D'Amore PA. The role of shear-induced transforming growth factor-ß signaling in the endothelium. Arterioscler Thromb Vasc Biol. 2013 Nov; 33(11):2608-17. PMID: 23968981.
    Citations: 13     Fields:    Translation:HumansCells
  30. Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW. Epoxyeicosanoids promote organ and tissue regeneration. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13528-33. PMID: 23898174.
    Citations: 40     Fields:    Translation:AnimalsCells
  31. Bagchi M, Kim LA, Boucher J, Walshe TE, Kahn CR, D'Amore PA. Vascular endothelial growth factor is important for brown adipose tissue development and maintenance. FASEB J. 2013 Aug; 27(8):3257-71. PMID: 23682123.
    Citations: 20     Fields:    Translation:AnimalsCells
  32. Bielenberg DR, D'Amore PA. All vessels are not created equal. Am J Pathol. 2013 Apr; 182(4):1087-91. PMID: 23422091.
    Citations: 1     Fields:    Translation:HumansAnimals
  33. Tseng WA, Thein T, Kinnunen K, Lashkari K, Gregory MS, D'Amore PA, Ksander BR. NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration. Invest Ophthalmol Vis Sci. 2013 Jan 07; 54(1):110-20. PMID: 23221073.
    Citations: 71     Fields:    Translation:HumansCells
  34. Jia D, Hasso SM, Chan J, Filingeri D, D'Amore PA, Rice L, Pampo C, Siemann DW, Zurakowski D, Rodig SJ, Moses MA. Transcriptional repression of VEGF by ZNF24: mechanistic studies and vascular consequences in vivo. Blood. 2013 Jan 24; 121(4):707-15. PMID: 23212515.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  35. Ford KM, Saint-Geniez M, Walshe TE, D'Amore PA. Expression and role of VEGF--a in the ciliary body. Invest Ophthalmol Vis Sci. 2012 Nov 07; 53(12):7520-7. PMID: 23081980.
    Citations: 9     Fields:    Translation:Animals
  36. Kim LA, D'Amore PA. A brief history of anti-VEGF for the treatment of ocular angiogenesis. Am J Pathol. 2012 Aug; 181(2):376-9. PMID: 22749677.
    Citations: 18     Fields:    Translation:HumansAnimals
  37. Maruyama K, Nakazawa T, Cursiefen C, Maruyama Y, Van Rooijen N, D'Amore PA, Kinoshita S. The maintenance of lymphatic vessels in the cornea is dependent on the presence of macrophages. Invest Ophthalmol Vis Sci. 2012 May 31; 53(6):3145-53. PMID: 22511631.
    Citations: 12     Fields:    Translation:AnimalsCells
  38. Ford KM, D'Amore PA. Molecular regulation of vascular endothelial growth factor expression in the retinal pigment epithelium. Mol Vis. 2012; 18:519-27. PMID: 22419845.
    Citations: 10     Fields:    Translation:HumansCells
  39. dela Paz NG, Walshe TE, Leach LL, Saint-Geniez M, D'Amore PA. Role of shear-stress-induced VEGF expression in endothelial cell survival. J Cell Sci. 2012 Feb 15; 125(Pt 4):831-43. PMID: 22399811.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  40. Cao Y, Arbiser J, D'Amato RJ, D'Amore PA, Ingber DE, Kerbel R, Klagsbrun M, Lim S, Moses MA, Zetter B, Dvorak H, Langer R. Forty-year journey of angiogenesis translational research. Sci Transl Med. 2011 Dec 21; 3(114):114rv3. PMID: 22190240.
    Citations: 60     Fields:    Translation:Humans
  41. Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnés CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW, Zeldin DC. Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. J Clin Invest. 2012 Jan; 122(1):178-91. PMID: 22182838.
    Citations: 69     Fields:    Translation:HumansAnimals
  42. Ford KM, Saint-Geniez M, Walshe T, Zahr A, D'Amore PA. Expression and role of VEGF in the adult retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2011 Dec 09; 52(13):9478-87. PMID: 22058334.
    Citations: 41     Fields:    Translation:AnimalsCells
  43. Sekiyama E, Saint-Geniez M, Yoneda K, Hisatomi T, Nakao S, Walshe TE, Maruyama K, Hafezi-Moghadam A, Miller JW, Kinoshita S, D'Amore PA. Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity. FASEB J. 2012 Feb; 26(2):567-75. PMID: 22067481.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  44. Darland DC, Cain JT, Berosik MA, Saint-Geniez M, Odens PW, Schaubhut GJ, Frisch S, Stemmer-Rachamimov A, Darland T, D'Amore PA. Vascular endothelial growth factor (VEGF) isoform regulation of early forebrain development. Dev Biol. 2011 Oct 01; 358(1):9-22. PMID: 21803034.
    Citations: 12     Fields:    Translation:Animals
  45. Walshe TE, Leach LL, D'Amore PA. TGF-ß signaling is required for maintenance of retinal ganglion cell differentiation and survival. Neuroscience. 2011 Aug 25; 189:123-31. PMID: 21664439.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  46. Wang H, Geisen P, Wittchen ES, King B, Burridge K, D'Amore PA, Hartnett ME. The role of RPE cell-associated VEGF189 in choroidal endothelial cell transmigration across the RPE. Invest Ophthalmol Vis Sci. 2011 Jan; 52(1):570-8. PMID: 20811045.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  47. Patel-Hett S, D'Amore PA. Signal transduction in vasculogenesis and developmental angiogenesis. Int J Dev Biol. 2011; 55(4-5):353-63. PMID: 21732275.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  48. Lee YJ, Karl DL, Maduekwe UN, Rothrock C, Ryeom S, D'Amore PA, Yoon SS. Differential effects of VEGFR-1 and VEGFR-2 inhibition on tumor metastases based on host organ environment. Cancer Res. 2010 Nov 01; 70(21):8357-67. PMID: 20978198.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  49. Bryan BA, Dennstedt E, Mitchell DC, Walshe TE, Noma K, Loureiro R, Saint-Geniez M, Campaigniac JP, Liao JK, D'Amore PA. RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis. FASEB J. 2010 Sep; 24(9):3186-95. PMID: 20400538.
    Citations: 76     Fields:    Translation:HumansAnimalsCells
  50. D'Amore PA. Editorial. Microvasc Res. 2010 May; 79(3):161. PMID: 20171233.
    Citations:    Fields:    Translation:HumansAnimalsCells
  51. Fukumoto A, Maruyama K, Walsh T, Kajiya K, Hamuro J, D'Amore PA, Kinoshita S. Intracellular thiol redox status regulates lymphangiogenesis and dictates corneal limbal graft survival. Invest Ophthalmol Vis Sci. 2010 May; 51(5):2450-8. PMID: 20042658.
    Citations:    Fields:    Translation:AnimalsCells
  52. Saint-Geniez M, Kurihara T, Sekiyama E, Maldonado AE, D'Amore PA. An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18751-6. PMID: 19841260.
    Citations: 127     Fields:    Translation:AnimalsCells
  53. Nieves BJ, D'Amore PA, Bryan BA. The function of vascular endothelial growth factor. Biofactors. 2009 Jul-Aug; 35(4):332-7. PMID: 19415738.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  54. Walshe TE, Dole VS, Maharaj AS, Patten IS, Wagner DD, D'Amore PA. Inhibition of VEGF or TGF-{beta} signaling activates endothelium and increases leukocyte rolling. Arterioscler Thromb Vasc Biol. 2009 Aug; 29(8):1185-92. PMID: 19461051.
    Citations: 21     Fields:    Translation:AnimalsCells
  55. Walshe TE, Saint-Geniez M, Maharaj AS, Sekiyama E, Maldonado AE, D'Amore PA. TGF-beta is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature. PLoS One. 2009; 4(4):e5149. PMID: 19340291.
    Citations: 51     Fields:    Translation:AnimalsCells
  56. D'Amore P, D'Amato R. Seminars in Ophthalmology. Editorial. Semin Ophthalmol. 2009 Mar-Apr; 24(2):50-1. PMID: 19373686.
    Citations:    Fields:    Translation:HumansAnimals
  57. Saint-Geniez M, Maharaj AS, Walshe TE, Tucker BA, Sekiyama E, Kurihara T, Darland DC, Young MJ, D'Amore PA. Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors. PLoS One. 2008; 3(11):e3554. PMID: 18978936.
    Citations: 189     Fields:    Translation:AnimalsCells
  58. dela Paz NG, D'Amore PA. Arterial versus venous endothelial cells. Cell Tissue Res. 2009 Jan; 335(1):5-16. PMID: 18972135.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  59. Saint-Geniez M, Kurihara T, D'Amore PA. Role of cell and matrix-bound VEGF isoforms in lens development. Invest Ophthalmol Vis Sci. 2009 Jan; 50(1):311-21. PMID: 18757513.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  60. Sang DN, D'Amore PA. Is blockade of vascular endothelial growth factor beneficial for all types of diabetic retinopathy? Diabetologia. 2008 Sep; 51(9):1570-3. PMID: 18607560.
    Citations: 13     Fields:    Translation:Humans
  61. Chao W, D'Amore PA. IGF2: epigenetic regulation and role in development and disease. Cytokine Growth Factor Rev. 2008 Apr; 19(2):111-20. PMID: 18308616.
    Citations: 71     Fields:    Translation:HumansAnimalsCells
  62. Fernando NT, Koch M, Rothrock C, Gollogly LK, D'Amore PA, Ryeom S, Yoon SS. Tumor escape from endogenous, extracellular matrix-associated angiogenesis inhibitors by up-regulation of multiple proangiogenic factors. Clin Cancer Res. 2008 Mar 01; 14(5):1529-39. PMID: 18316578.
    Citations: 62     Fields:    Translation:AnimalsCells
  63. Maharaj AS, Walshe TE, Saint-Geniez M, Venkatesha S, Maldonado AE, Himes NC, Matharu KS, Karumanchi SA, D'Amore PA. VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma. J Exp Med. 2008 Feb 18; 205(2):491-501. PMID: 18268040.
    Citations: 45     Fields:    Translation:AnimalsCells
  64. Bielenberg DR, D'Amore PA. Judah Folkman's contribution to the inhibition of angiogenesis. Lymphat Res Biol. 2008; 6(3-4):203-7. PMID: 19093793.
    Citations:    Fields:    Translation:HumansAnimals
  65. Walshe TE, D'Amore PA. The role of hypoxia in vascular injury and repair. Annu Rev Pathol. 2008; 3:615-43. PMID: 18039132.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  66. Bryan BA, D'Amore PA. Pericyte isolation and use in endothelial/pericyte coculture models. Methods Enzymol. 2008; 443:315-31. PMID: 18772023.
    Citations: 24     Fields:    Translation:AnimalsCells
  67. Bryan BA, Walshe TE, Mitchell DC, Havumaki JS, Saint-Geniez M, Maharaj AS, Maldonado AE, D'Amore PA. Coordinated vascular endothelial growth factor expression and signaling during skeletal myogenic differentiation. Mol Biol Cell. 2008 Mar; 19(3):994-1006. PMID: 18094043.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  68. Harper J, Yan L, Loureiro RM, Wu I, Fang J, D'Amore PA, Moses MA. Repression of vascular endothelial growth factor expression by the zinc finger transcription factor ZNF24. Cancer Res. 2007 Sep 15; 67(18):8736-41. PMID: 17875714.
    Citations: 15     Fields:    Translation:HumansCells
  69. Bryan BA, D'Amore PA. What tangled webs they weave: Rho-GTPase control of angiogenesis. Cell Mol Life Sci. 2007 Aug; 64(16):2053-65. PMID: 17530172.
    Citations: 48     Fields:    Translation:AnimalsCells
  70. D'Amore PA. Vascular endothelial cell growth factor-a: not just for endothelial cells anymore. Am J Pathol. 2007 Jul; 171(1):14-8. PMID: 17591949.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  71. Ramsauer M, D'Amore PA. Contextual role for angiopoietins and TGFbeta1 in blood vessel stabilization. J Cell Sci. 2007 May 15; 120(Pt 10):1810-7. PMID: 17502485.
    Citations: 17     Fields:    Translation:AnimalsCells
  72. Maharaj AS, D'Amore PA. Roles for VEGF in the adult. Microvasc Res. 2007 Sep-Nov; 74(2-3):100-13. PMID: 17532010.
    Citations: 52     Fields:    Translation:Humans
  73. Maruyama K, Asai J, Ii M, Thorne T, Losordo DW, D'Amore PA. Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing. Am J Pathol. 2007 Apr; 170(4):1178-91. PMID: 17392158.
    Citations: 100     Fields:    Translation:AnimalsCells
  74. Goodwin AM, Kitajewski J, D'Amore PA. Wnt1 and Wnt5a affect endothelial proliferation and capillary length; Wnt2 does not. Growth Factors. 2007 Feb; 25(1):25-32. PMID: 17454147.
    Citations: 23     Fields:    Translation:AnimalsCells
  75. Goodwin AM, Sullivan KM, D'Amore PA. Cultured endothelial cells display endogenous activation of the canonical Wnt signaling pathway and express multiple ligands, receptors, and secreted modulators of Wnt signaling. Dev Dyn. 2006 Nov; 235(11):3110-20. PMID: 17013885.
    Citations: 48     Fields:    Translation:HumansCells
  76. Banerjee S, Sengupta K, Dhar K, Mehta S, D'Amore PA, Dhar G, Banerjee SK. Breast cancer cells secreted platelet-derived growth factor-induced motility of vascular smooth muscle cells is mediated through neuropilin-1. Mol Carcinog. 2006 Nov; 45(11):871-80. PMID: 16847823.
    Citations: 30     Fields:    Translation:HumansCells
  77. Saint-Geniez M, Maldonado AE, D'Amore PA. VEGF expression and receptor activation in the choroid during development and in the adult. Invest Ophthalmol Vis Sci. 2006 Jul; 47(7):3135-42. PMID: 16799060.
    Citations: 62     Fields:    Translation:AnimalsCells
  78. Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, Kim YM, Bdolah Y, Lim KH, Yuan HT, Libermann TA, Stillman IE, Roberts D, D'Amore PA, Epstein FH, Sellke FW, Romero R, Sukhatme VP, Letarte M, Karumanchi SA. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med. 2006 Jun; 12(6):642-9. PMID: 16751767.
    Citations: 401     Fields:    Translation:HumansAnimalsCells
  79. Lutty GA, Chan-Ling T, Phelps DL, Adamis AP, Berns KI, Chan CK, Cole CH, D'Amore PA, Das A, Deng WT, Dobson V, Flynn JT, Friedlander M, Fulton A, Good WV, Grant MB, Hansen R, Hauswirth WW, Hardy RJ, Hinton DR, Hughes S, McLeod DS, Palmer EA, Patz A, Penn JS, Raisler BJ, Repka MX, Saint-Geniez M, Shaw LC, Shima DT, Smith BT, Smith LE, Tahija SG, Tasman W, Trese MT. Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). Mol Vis. 2006 May 23; 12:532-80. PMID: 16735995.
    Citations: 16     Fields:    Translation:Humans
  80. Maharaj AS, Saint-Geniez M, Maldonado AE, D'Amore PA. Vascular endothelial growth factor localization in the adult. Am J Pathol. 2006 Feb; 168(2):639-48. PMID: 16436677.
    Citations: 80     Fields:    Translation:AnimalsCells
  81. Suburo AM, D'Amore PA. Development of the endothelium. Handb Exp Pharmacol. 2006; (176 Pt 1):71-105. PMID: 16999217.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  82. Maruyama K, Ii M, Cursiefen C, Jackson DG, Keino H, Tomita M, Van Rooijen N, Takenaka H, D'Amore PA, Stein-Streilein J, Losordo DW, Streilein JW. Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages. J Clin Invest. 2005 Sep; 115(9):2363-72. PMID: 16138190.
    Citations: 188     Fields:    Translation:AnimalsCells
  83. Detwiller KY, Fernando NT, Segal NH, Ryeom SW, D'Amore PA, Yoon SS. Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A. Cancer Res. 2005 Jul 01; 65(13):5881-9. PMID: 15994966.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  84. Levenberg S, Rouwkema J, Macdonald M, Garfein ES, Kohane DS, Darland DC, Marini R, van Blitterswijk CA, Mulligan RC, D'Amore PA, Langer R. Engineering vascularized skeletal muscle tissue. Nat Biotechnol. 2005 Jul; 23(7):879-84. PMID: 15965465.
    Citations: 250     Fields:    Translation:HumansAnimalsCells
  85. Arboleda-Velasquez JF, Rampal R, Fung E, Darland DC, Liu M, Martinez MC, Donahue CP, Navarro-Gonzalez MF, Libby P, D'Amore PA, Aikawa M, Haltiwanger RS, Kosik KS. CADASIL mutations impair Notch3 glycosylation by Fringe. Hum Mol Genet. 2005 Jun 15; 14(12):1631-9. PMID: 15857853.
    Citations: 10     Fields:    Translation:AnimalsCells
  86. Loureiro RM, D'Amore PA. Transcriptional regulation of vascular endothelial growth factor in cancer. Cytokine Growth Factor Rev. 2005 Feb; 16(1):77-89. PMID: 15733833.
    Citations: 41     Fields:    Translation:AnimalsCells
  87. Loureiro RM, Maharaj AS, Dankort D, Muller WJ, D'Amore PA. ErbB2 overexpression in mammary cells upregulates VEGF through the core promoter. Biochem Biophys Res Commun. 2005 Jan 14; 326(2):455-65. PMID: 15582599.
    Citations: 11     Fields:    Translation:AnimalsCells
  88. Runnels JM, Poureshagh M, Novak J, D'Amore PA. Detection of circulating endothelial precursor cells by in vivo flow cytometry. IOVS. 2005.
  89. Nishijimam K, Jo N, Ng Y-S, Robinson GS, D'Amore PA, Shima DT, Adamis AP. VEGF 164 governs leukocyte dynamics and pathological neovascularization. IOVS. 2005.
  90. Darland DC, Saint-Geniez M, Chen J, Benezra R, D'Amore PA. Expression of ld 1 protein in developing retinal vasculature. IOVS. 2005.
  91. Morris PN, Dunmore BJ, Tadros A, Marchuk DA, Darland DC, D'Amore PA, Brindle NP. Functional analysis of a mutant form of the receptor tyrosine kinase Tie2 causing venous malformations. J Mol Med (Berl). 2005 Jan; 83(1):58-63. PMID: 15526080.
    Citations: 11     Fields:    Translation:HumansCells
  92. Ding R, Darland DC, Parmacek MS, D'Amore PA. Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation. Stem Cells Dev. 2004 Oct; 13(5):509-20. PMID: 15588508.
    Citations: 22     Fields:    Translation:AnimalsCells
  93. Ng YS, Ramsauer M, Loureiro RM, D'Amore PA. Identification of genes involved in VEGF-mediated vascular morphogenesis using embryonic stem cell-derived cystic embryoid bodies. Lab Invest. 2004 Sep; 84(9):1209-18. PMID: 15220937.
    Citations: 19     Fields:    Translation:AnimalsCells
  94. Garcia CM, Darland DC, Massingham LJ, D'Amore PA. Endothelial cell-astrocyte interactions and TGF beta are required for induction of blood-neural barrier properties. Brain Res Dev Brain Res. 2004 Aug 18; 152(1):25-38. PMID: 15283992.
    Citations: 31     Fields:    Translation:AnimalsCells
  95. Chang R, Andreoli S, Ng YS, Truong T, Smith SR, Wilson J, D'Amore PA. VEGF expression is downregulated in nitrofen-induced congenital diaphragmatic hernia. J Pediatr Surg. 2004 Jun; 39(6):825-8; discussion 825-8. PMID: 15185205.
    Citations: 10     Fields:    Translation:AnimalsCells
  96. Cursiefen C, Chen L, Borges LP, Jackson D, Cao J, Radziejewski C, D'Amore PA, Dana MR, Wiegand SJ, Streilein JW. VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest. 2004 Apr; 113(7):1040-50. PMID: 15057311.
    Citations: 279     Fields:    Translation:AnimalsCells
  97. Beck LH, Goodwin AM, D'Amore PA. Culture of large vessel endothelial cells on floating collagen gels promotes a phenotype characteristic of endothelium in vivo. Differentiation. 2004 Apr; 72(4):162-70. PMID: 15157239.
    Citations: 2     Fields:    Translation:HumansCells
  98. Saint-Geniez M, D'Amore PA. Development and pathology of the hyaloid, choroidal and retinal vasculature. Int J Dev Biol. 2004; 48(8-9):1045-58. PMID: 15558494.
    Citations: 114     Fields:    Translation:HumansAnimals
  99. Darland DC, Massingham LJ, Smith SR, Piek E, Saint-Geniez M, D'Amore PA. Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival. Dev Biol. 2003 Dec 01; 264(1):275-88. PMID: 14623248.
    Citations: 112     Fields:    Translation:HumansAnimalsCells
  100. Hartnett ME, Lappas A, Darland D, McColm JR, Lovejoy S, D'Amore PA. Retinal pigment epithelium and endothelial cell interaction causes retinal pigment epithelial barrier dysfunction via a soluble VEGF-dependent mechanism. Exp Eye Res. 2003 Nov; 77(5):593-9. PMID: 14550401.
    Citations: 27     Fields:    Translation:AnimalsCells
  101. Ishida S, Usui T, Yamashiro K, Kaji Y, Amano S, Ogura Y, Hida T, Oguchi Y, Ambati J, Miller JW, Gragoudas ES, Ng YS, D'Amore PA, Shima DT, Adamis AP. VEGF164-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization. J Exp Med. 2003 Aug 04; 198(3):483-9. PMID: 12900522.
    Citations: 117     Fields:    Translation:AnimalsCells
  102. Ramsauer M, D'Amore PA. Getting Tie(2)d up in angiogenesis. J Clin Invest. 2002 Dec; 110(11):1615-7. PMID: 12464666.
    Citations: 17     Fields:    Translation:Humans
  103. D'Amore PA, Ng YS. Won't you be my neighbor? Local induction of arteriogenesis. Cell. 2002 Aug 09; 110(3):289-92. PMID: 12176316.
    Citations: 9     Fields:    Translation:HumansAnimals
  104. Galambos C, Ng YS, Ali A, Noguchi A, Lovejoy S, D'Amore PA, DeMello DE. Defective pulmonary development in the absence of heparin-binding vascular endothelial growth factor isoforms. Am J Respir Cell Mol Biol. 2002 Aug; 27(2):194-203. PMID: 12151311.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  105. D'Amore PA, Ng YS. Tales of the cryptic: unveiling more angiogenesis inhibitors. Trends Mol Med. 2002 Jul; 8(7):313-5. PMID: 12114105.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  106. Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR. Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr; 129(8):1893-904. PMID: 11934855.
    Citations: 105     Fields:    Translation:AnimalsCells
  107. Stalmans I, Ng YS, Rohan R, Fruttiger M, Bouché A, Yuce A, Fujisawa H, Hermans B, Shani M, Jansen S, Hicklin D, Anderson DJ, Gardiner T, Hammes HP, Moons L, Dewerchin M, Collen D, Carmeliet P, D'Amore PA. Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms. J Clin Invest. 2002 Feb; 109(3):327-36. PMID: 11827992.
    Citations: 144     Fields:    Translation:AnimalsCells
  108. Goodwin AM, D'Amore PA. Wnt signaling in the vasculature. Angiogenesis. 2002; 5(1-2):1-9. PMID: 12549854.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  109. Ng YS, Rohan R, Sunday ME, Demello DE, D'Amore PA. Differential expression of VEGF isoforms in mouse during development and in the adult. Dev Dyn. 2001 Feb; 220(2):112-21. PMID: 11169844.
    Citations: 107     Fields:    Translation:AnimalsCells
  110. Ng YS, D'Amore PA. Therapeutic angiogenesis for cardiovascular disease. Curr Control Trials Cardiovasc Med. 2001; 2(6):278-285. PMID: 11806814.
    Citations: 4     
  111. Darland DC, D'Amore PA. Cell-cell interactions in vascular development. Curr Top Dev Biol. 2001; 52:107-49. PMID: 11529428.
    Citations: 37     Fields:    Translation:AnimalsCells
  112. Nguyen LL, D'Amore PA. Cellular interactions in vascular growth and differentiation. Int Rev Cytol. 2001; 204:1-48. PMID: 11243594.
    Citations: 11     Fields:    Translation:HumansAnimals
  113. Darland DC, D'Amore PA. TGF beta is required for the formation of capillary-like structures in three-dimensional cocultures of 10T1/2 and endothelial cells. Angiogenesis. 2001; 4(1):11-20. PMID: 11824373.
    Citations: 47     Fields:    Translation:AnimalsCells
  114. D'Amore PA. Kissing cousins-evidence for a common vascular cell precursor. Nat Med. 2000 Dec; 6(12):1323-4. PMID: 11100113.
    Citations: 2     Fields:    Translation:Cells
  115. Dennis S, Aikawa M, Szeto W, d'Amore PA, Papkoff J. A secreted frizzled related protein, FrzA, selectively associates with Wnt-1 protein and regulates wnt-1 signaling. J Cell Sci. 1999 Nov; 112 ( Pt 21):3815-20. PMID: 10523516.
    Citations: 27     Fields:    Translation:Cells
  116. Hartnett ME, Garcia CM, D'Amore PA. Release of bFGF, an endothelial cell survival factor, by osmotic shock. Invest Ophthalmol Vis Sci. 1999 Nov; 40(12):2945-51. PMID: 10549656.
    Citations: 3     Fields:    Translation:AnimalsCells
  117. Grosskreutz CL, Anand-Apte B, Dupláa C, Quinn TP, Terman BI, Zetter B, D'Amore PA. Vascular endothelial growth factor-induced migration of vascular smooth muscle cells in vitro. Microvasc Res. 1999 Sep; 58(2):128-36. PMID: 10458928.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  118. Duplàa C, Jaspard B, Moreau C, D'Amore PA. Identification and cloning of a secreted protein related to the cysteine-rich domain of frizzled. Evidence for a role in endothelial cell growth control. Circ Res. 1999 Jun 25; 84(12):1433-45. PMID: 10381896.
    Citations: 15     Fields:    Translation:AnimalsCells
  119. Carmeliet P, Ng YS, Nuyens D, Theilmeier G, Brusselmans K, Cornelissen I, Ehler E, Kakkar VV, Stalmans I, Mattot V, Perriard JC, Dewerchin M, Flameng W, Nagy A, Lupu F, Moons L, Collen D, D'Amore PA, Shima DT. Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Nat Med. 1999 May; 5(5):495-502. PMID: 10229225.
    Citations: 132     Fields:    Translation:AnimalsCells
  120. Hirschi KK, Rohovsky SA, Beck LH, Smith SR, D'Amore PA. Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact. Circ Res. 1999 Feb 19; 84(3):298-305. PMID: 10024303.
    Citations: 88     Fields:    Translation:AnimalsCells
  121. Darland DC, D'Amore PA. Blood vessel maturation: vascular development comes of age. J Clin Invest. 1999 Jan; 103(2):157-8. PMID: 9916126.
    Citations: 55     Fields:    
  122. Xu Q, D'Amore PA, Sokol SY. Functional and biochemical interactions of Wnts with FrzA, a secreted Wnt antagonist. Development. 1998 Dec; 125(23):4767-76. PMID: 9806925.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  123. Hirschi KK, Rohovsky SA, D'Amore PA. PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate. J Cell Biol. 1998 May 04; 141(3):805-14. PMID: 9566978.
    Citations: 209     Fields:    Translation:Animals
  124. Hirschi KK, Rohovsky SA, D'Amore PA. Cell-cell interactions in vessel assembly: a model for the fundamentals of vascular remodelling. Transpl Immunol. 1997 Sep; 5(3):177-8. PMID: 9402682.
    Citations: 11     Fields:    Translation:HumansAnimals
  125. Beck L, D'Amore PA. Vascular development: cellular and molecular regulation. FASEB J. 1997 Apr; 11(5):365-73. PMID: 9141503.
    Citations: 80     Fields:    Translation:AnimalsCells
  126. Hirschi KK, D'Amore PA. Control of angiogenesis by the pericyte: molecular mechanisms and significance. EXS. 1997; 79:419-28. PMID: 9002230.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  127. Folkman J, D'Amore PA. Blood vessel formation: what is its molecular basis? Cell. 1996 Dec 27; 87(7):1153-5. PMID: 8980221.
    Citations: 197     Fields:    Translation:HumansAnimalsCells
  128. Rohovsky S, Kearney M, Pieczek A, Rosenfield K, Schainfeld R, D'Amore PA, Isner JM. Elevated levels of basic fibroblast growth factor in patients with limb ischemia. Am Heart J. 1996 Nov; 132(5):1015-9. PMID: 8892777.
    Citations: 2     Fields:    Translation:HumansCells
  129. Hirschi KK, D'Amore PA. Pericytes in the microvasculature. Cardiovasc Res. 1996 Oct; 32(4):687-98. PMID: 8915187.
    Citations: 188     Fields:    Translation:HumansAnimalsCells
  130. Klagsbrun M, D'Amore PA. Vascular endothelial growth factor and its receptors. Cytokine Growth Factor Rev. 1996 Oct; 7(3):259-70. PMID: 8971481.
    Citations: 63     Fields:    Translation:HumansAnimals
  131. Dethlefsen SM, Shepro D, D'Amore PA. Comparison of the effects of mechanical stimulation on venous and arterial smooth muscle cells in vitro. J Vasc Res. 1996 Sep-Oct; 33(5):405-13. PMID: 8862146.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  132. Luo Y, D'Amore PA, Dorf ME. Beta-chemokine TCA3 binds to and activates rat vascular smooth muscle cells. J Immunol. 1996 Sep 01; 157(5):2143-8. PMID: 8757339.
    Citations: 4     Fields:    Translation:AnimalsCells
  133. Shima DT, Gougos A, Miller JW, Tolentino M, Robinson G, Adamis AP, D'Amore PA. Cloning and mRNA expression of vascular endothelial growth factor in ischemic retinas of Macaca fascicularis. Invest Ophthalmol Vis Sci. 1996 Jun; 37(7):1334-40. PMID: 8641836.
    Citations: 22     Fields:    Translation:AnimalsCells
  134. D'Amore PA, Shima DT. Tumor angiogenesis: a physiological process or genetically determined? Cancer Metastasis Rev. 1996 Jun; 15(2):205-12. PMID: 8842492.
    Citations: 4     Fields:    Translation:HumansAnimals
  135. Shima DT, Kuroki M, Deutsch U, Ng YS, Adamis AP, D'Amore PA. The mouse gene for vascular endothelial growth factor. Genomic structure, definition of the transcriptional unit, and characterization of transcriptional and post-transcriptional regulatory sequences. J Biol Chem. 1996 Feb 16; 271(7):3877-83. PMID: 8632007.
    Citations: 72     Fields:    Translation:HumansAnimalsCells
  136. Adamis AP, Shima DT, Tolentino MJ, Gragoudas ES, Ferrara N, Folkman J, D'Amore PA, Miller JW. Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate. Arch Ophthalmol. 1996 Jan; 114(1):66-71. PMID: 8540853.
    Citations: 92     Fields:    Translation:Animals
  137. Kostyk SK, Kourembanas S, Wheeler EL, Medeiros D, McQuillan LP, D'Amore PA, Braunhut SJ. Basic fibroblast growth factor increases nitric oxide synthase production in bovine endothelial cells. Am J Physiol. 1995 Nov; 269(5 Pt 2):H1583-9. PMID: 7503252.
    Citations: 11     Fields:    Translation:AnimalsCells
  138. Shima DT, Deutsch U, D'Amore PA. Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability. FEBS Lett. 1995 Aug 21; 370(3):203-8. PMID: 7656977.
    Citations: 55     Fields:    Translation:HumansCells
  139. Ku PT, D'Amore PA. Regulation of basic fibroblast growth factor (bFGF) gene and protein expression following its release from sublethally injured endothelial cells. J Cell Biochem. 1995 Jul; 58(3):328-43. PMID: 7593255.
    Citations: 17     Fields:    Translation:AnimalsCells
  140. Shima DT, Saunders KB, Gougos A, D'Amore PA. Alterations in gene expression associated with changes in the state of endothelial differentiation. Differentiation. 1995 Feb; 58(3):217-26. PMID: 7713329.
    Citations: 3     Fields:    Translation:AnimalsCells
  141. Shima DT, Adamis AP, Ferrara N, Yeo KT, Yeo TK, Allende R, Folkman J, D'Amore PA. Hypoxic induction of endothelial cell growth factors in retinal cells: identification and characterization of vascular endothelial growth factor (VEGF) as the mitogen. Mol Med. 1995 Jan; 1(2):182-93. PMID: 8529097.
    Citations: 61     Fields:    Translation:HumansCells
  142. D'Amore PA. Mechanisms of retinal and choroidal neovascularization. Invest Ophthalmol Vis Sci. 1994 Nov; 35(12):3974-9. PMID: 7525506.
    Citations: 58     Fields:    Translation:HumansAnimals
  143. Smith S, D'Amore PA, Dreyer EB. Comparative toxicity of mitomycin C and 5-fluorouracil in vitro. Am J Ophthalmol. 1994 Sep 15; 118(3):332-7. PMID: 8085590.
    Citations: 17     Fields:    Translation:AnimalsCells
  144. Miller JW, Adamis AP, Shima DT, D'Amore PA, Moulton RS, O'Reilly MS, Folkman J, Dvorak HF, Brown LF, Berse B, et al. Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model. Am J Pathol. 1994 Sep; 145(3):574-84. PMID: 7521577.
    Citations: 148     Fields:    Translation:Animals
  145. Dethlefsen SM, Shepro D, D'Amore PA. Arachidonic acid metabolites in bFGF-, PDGF-, and serum-stimulated vascular cell growth. Exp Cell Res. 1994 Jun; 212(2):262-73. PMID: 8187818.
    Citations: 9     Fields:    Translation:AnimalsCells
  146. D'Amore PA, Brown RH, Ku PT, Hoffman EP, Watanabe H, Arahata K, Ishihara T, Folkman J. Elevated basic fibroblast growth factor in the serum of patients with Duchenne muscular dystrophy. Ann Neurol. 1994 Mar; 35(3):362-5. PMID: 8122890.
    Citations: 18     Fields:    Translation:Humans
  147. Kostyk SK, D'Amore PA, Herman IM, Wagner JA. Optic nerve injury alters basic fibroblast growth factor localization in the retina and optic tract. J Neurosci. 1994 Mar; 14(3 Pt 2):1441-9. PMID: 7510332.
    Citations: 15     Fields:    Translation:Animals
  148. RayChaudhury A, Frazier WA, D'Amore PA. Comparison of normal and tumorigenic endothelial cells: differences in thrombospondin production and responses to transforming growth factor-beta. J Cell Sci. 1994 Jan; 107 ( Pt 1):39-46. PMID: 8175921.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  149. Smith LE, Wesolowski E, McLellan A, Kostyk SK, D'Amato R, Sullivan R, D'Amore PA. Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci. 1994 Jan; 35(1):101-11. PMID: 7507904.
    Citations: 509     Fields:    Translation:HumansAnimals
  150. Liu Z, D'Amore PA, Mikati M, Gatt A, Holmes GL. Neuroprotective effect of chronic infusion of basic fibroblast growth factor on seizure-associated hippocampal damage. Brain Res. 1993 Oct 29; 626(1-2):335-8. PMID: 8281447.
    Citations: 9     Fields:    Translation:AnimalsCells
  151. Dodge AB, Lu X, D'Amore PA. Density-dependent endothelial cell production of an inhibitor of smooth muscle cell growth. J Cell Biochem. 1993 Sep; 53(1):21-31. PMID: 8227180.
    Citations: 11     Fields:    Translation:AnimalsCells
  152. Adamis AP, Shima DT, Yeo KT, Yeo TK, Brown LF, Berse B, D'Amore PA, Folkman J. Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells. Biochem Biophys Res Commun. 1993 Jun 15; 193(2):631-8. PMID: 8512562.
    Citations: 74     Fields:    Translation:HumansCells
  153. D'Amore PA, Smith SR. Growth factor effects on cells of the vascular wall: a survey. Growth Factors. 1993; 8(1):61-75. PMID: 7680568.
    Citations: 28     Fields:    Translation:AnimalsCells
  154. Dodge AB, D'Amore PA. Cell-cell interactions in diabetic angiopathy. Diabetes Care. 1992 Sep; 15(9):1168-80. PMID: 1396014.
    Citations: 3     Fields:    Translation:Humans
  155. Braunhut SJ, D'Amore PA, Gudas LJ. The location and expression of fibroblast growth factor (FGF) in F9 visceral and parietal embryonic cells after retinoic acid-induced differentiation. Differentiation. 1992 Aug; 50(3):141-52. PMID: 1426701.
    Citations: 1     Fields:    Translation:AnimalsCells
  156. Saunders KB, D'Amore PA. An in vitro model for cell-cell interactions. In Vitro Cell Dev Biol. 1992 Jul-Aug; 28A(7-8):521-8. PMID: 1522045.
    Citations: 13     Fields:    Translation:Animals
  157. Damon DH, Halegoua S, D'Amore P, Wagner JA. Rapid fibroblast growth factor-induced increases in protein phosphorylation and ornithine decarboxylase activity: regulation by heparin and comparison to nerve growth factor-induced increases. Exp Cell Res. 1992 Jul; 201(1):154-9. PMID: 1351851.
    Citations: 1     Fields:    Translation:AnimalsCells
  158. D'Amore PA. Capillary growth: a two-cell system. Semin Cancer Biol. 1992 Apr; 3(2):49-56. PMID: 1378309.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  159. Smith LE, Sweet E, Freedman S, D'Amore PA. Alterations in endothelial superoxide dismutase levels as a function of growth state in vitro. Invest Ophthalmol Vis Sci. 1992 Jan; 33(1):36-41. PMID: 1730547.
    Citations: 1