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profileTanuja Chitnis, M.D.

TitleAssociate Professor of Neurology
InstitutionBrigham and Women's Hospital
DepartmentNeurology
Address1 Brookline Pl. Suite 602
Brookline MA 02445
Phone617/525-5374
Fax617/525-5501
vCardDownload vCard (login for email)

Collapse Mentoring 
Collapse completed student projects
Demographic Characteristics and Progression of PPMS in the CLIMB Study Population
Summer, 06/10/12 - 08/17/12

Collapse Research 
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
K08NS047669     (CHITNIS, TANUJA)Jul 15, 2005 - Jun 30, 2010
NIH/NINDS
Mechanisms of Neurodegeneration &Neuroprotection in EAE
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Gianfrancesco MA, Stridh P, Shao X, Rhead B, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Schaefer C, Barcellos LF, Waubant E. Genetic risk factors for pediatric-onset multiple sclerosis. Mult Scler. 2017 Oct 01; 1352458517733551. PMID: 28980494.
    View in: PubMed
  2. Palacios N, Munger KL, Fitzgerald KC, Hart JE, Chitnis T, Ascherio A, Laden F. Exposure to particulate matter air pollution and risk of multiple sclerosis in two large cohorts of US nurses. Environ Int. 2017 Sep 19; 109:64-72. PMID: 28938101.
    View in: PubMed
  3. Chitnis T, Weiner HL. CNS inflammation and neurodegeneration. J Clin Invest. 2017 Oct 02; 127(10):3577-3587. PMID: 28872464.
    View in: PubMed
  4. Cortese M, Yuan C, Chitnis T, Ascherio A, Munger KL. No association between dietary sodium intake and the risk of multiple sclerosis. Neurology. 2017 Sep 26; 89(13):1322-1329. PMID: 28842447.
    View in: PubMed
  5. Greeke EE, Chua AS, Healy BC, Rintell DJ, Chitnis T, Glanz BI. Depression and fatigue in patients with multiple sclerosis. J Neurol Sci. 2017 Sep 15; 380:236-241. PMID: 28870578.
    View in: PubMed
  6. Sattarnezhad N, Farrow S, Kimbrough D, Glanz B, Healy B, Chitnis T. Agreement analysis comparing iPad LCVA and Sloan testing in multiple sclerosis patients. Mult Scler. 2017 Jun 01; 1352458517713667. PMID: 28585909.
    View in: PubMed
  7. Pakpoor J, Seminatore B, Graves JS, Schreiner T, Waldman AT, Lotze TE, Belman A, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, McDonald JC, Hart J, Ness JM, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Mar S, Kahn I, Rose J, Carmichael SL, Roalstad S, Waltz M, Casper TC, Waubant E. Dietary factors and pediatric multiple sclerosis: A case-control study. Mult Scler. 2017 Jun 01; 1352458517713343. PMID: 28608728.
    View in: PubMed
  8. Zhao Y, Healy BC, Rotstein D, Guttmann CR, Bakshi R, Weiner HL, Brodley CE, Chitnis T. Exploration of machine learning techniques in predicting multiple sclerosis disease course. PLoS One. 2017; 12(4):e0174866. PMID: 28379999.
    View in: PubMed
  9. Graves JS, Chitnis T, Weinstock-Guttman B, Rubin J, Zelikovitch AS, Nourbakhsh B, Simmons T, Waltz M, Casper TC, Waubant E. Maternal and Perinatal Exposures Are Associated With Risk for Pediatric-Onset Multiple Sclerosis. Pediatrics. 2017 Apr; 139(4). PMID: 28562303.
    View in: PubMed
  10. Gianfrancesco MA, Stridh P, Rhead B, Shao X, Xu E, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Bäärnhielm M, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Metayer C, Schaefer C, Barcellos LF, Waubant E. Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS. Neurology. 2017 Apr 25; 88(17):1623-1629. PMID: 28356466.
    View in: PubMed
  11. Bove R, Elsone L, Alvarez E, Borisow N, Cortez MM, Mateen FJ, Mealy MA, Mutch K, Tobyne S, Ruprecht K, Buckle G, Levy M, Wingerchuk DM, Paul F, Cross AH, Weinshenker B, Jacob A, Klawiter EC, Chitnis T. Female hormonal exposures and neuromyelitis optica symptom onset in a multicenter study. Neurol Neuroimmunol Neuroinflamm. 2017 May; 4(3):e339. PMID: 28382320.
    View in: PubMed
  12. Healy BC, Buckle GJ, Ali EN, Egorova S, Khalid F, Tauhid S, Glanz BI, Chitnis T, Guttmann CRG, Weiner HL, Bakshi R. Characterizing Clinical and MRI Dissociation in Patients with Multiple Sclerosis. J Neuroimaging. 2017 Sep; 27(5):481-485. PMID: 28261936.
    View in: PubMed
  13. Regev K, Healy BC, Khalid F, Paul A, Chu R, Tauhid S, Tummala S, Diaz-Cruz C, Raheja R, Mazzola MA, von Glehn F, Kivisakk P, Dupuy SL, Kim G, Chitnis T, Weiner HL, Gandhi R, Bakshi R. Association Between Serum MicroRNAs and Magnetic Resonance Imaging Measures of Multiple Sclerosis Severity. JAMA Neurol. 2017 Mar 01; 74(3):275-285. PMID: 28114622.
    View in: PubMed
  14. Bourne T, Waltz M, Casper TC, Kavak K, Aaen G, Belman A, Benson L, Candee M, Chitnis T, Graves J, Greenberg B, Gorman M, Harris Y, Krupp L, Lotze T, Mar S, Ness J, Olsen C, Roalstad S, Rodriguez M, Rose J, Rubin J, Schreiner T, Tillema JM, Kahn I, Waldman A, Barcellos L, Waubant E, Weinstock-Guttman B. Evaluating the association of allergies with multiple sclerosis susceptibility risk and disease activity in a pediatric population. J Neurol Sci. 2017 Apr 15; 375:371-375. PMID: 28320170.
    View in: PubMed
  15. Kim G, Chu R, Yousuf F, Tauhid S, Stazzone L, Houtchens MK, Stankiewicz JM, Severson C, Kimbrough D, Quintana FJ, Chitnis T, Weiner HL, Healy BC, Bakshi R. Sample size requirements for one-year treatment effects using deep gray matter volume from 3T MRI in progressive forms of multiple sclerosis. Int J Neurosci. 2017 Nov; 127(11):971-980. PMID: 28100092.
    View in: PubMed
  16. Bove R, Rankin K, Chua AS, Saraceno T, Sattarnezhad N, Greeke E, Stuart F, LaRussa A, Glanz BI, Chitnis T. Oral contraceptives and MS disease activity in a contemporary real-world cohort. Mult Scler. 2017 Feb 01; 1352458517692420. PMID: 28155573.
    View in: PubMed
  17. Bradshaw MJ, Vu N, Hunley TE, Chitnis T. Child Neurology: Neuromyelitis optica spectrum disorders. Neurology. 2017 Jan 10; 88(2):e10-e13. PMID: 28069981.
    View in: PubMed
  18. Bjørnevik K, Chitnis T, Ascherio A, Munger KL. Polyunsaturated fatty acids and the risk of multiple sclerosis. Mult Scler. 2017 Jan 01; 1352458517691150. PMID: 28156186.
    View in: PubMed
  19. Koelman DL, Benkeser DC, Xu Y, Neo SX, Tan K, Katsuno M, Sobue G, Natsume J, Chahin S, Mar SS, Venkatesan A, Chitnis T, Hoganson GM, Yeshokumar AK, Barreras P, Majmudar B, Carone M, Mateen FJ. Acute disseminated encephalomyelitis in China, Singapore and Japan: a comparison with the USA. Eur J Neurol. 2017 Feb; 24(2):391-396. PMID: 28009079.
    View in: PubMed
  20. Chitnis T, Graves J, Weinstock-Guttman B, Belman A, Olsen C, Misra M, Aaen G, Benson L, Candee M, Gorman M, Greenberg B, Krupp L, Lotze T, Mar S, Ness J, Rose J, Rubin J, Schreiner T, Tillema J, Waldman A, Rodriguez M, Casper C, Waubant E. Distinct effects of obesity and puberty on risk and age at onset of pediatric MS. Ann Clin Transl Neurol. 2016 Dec; 3(12):897-907. PMID: 28097202.
    View in: PubMed
  21. Barra ME, Soni D, Vo KH, Chitnis T, Stankiewicz JM. Experience with long-term rituximab use in a multiple sclerosis clinic. Mult Scler J Exp Transl Clin. 2016 Jan-Dec; 2:2055217316672100. PMID: 28607739.
    View in: PubMed
  22. Davoudi V, Keyhanian K, Bove RM, Chitnis T. Immunology of neuromyelitis optica during pregnancy. Neurol Neuroimmunol Neuroinflamm. 2016 Dec; 3(6):e288. PMID: 27761482.
    View in: PubMed
  23. Dorans KS, Massa J, Chitnis T, Ascherio A, Munger KL. Physical activity and the incidence of multiple sclerosis. Neurology. 2016 Oct 25; 87(17):1770-1776. PMID: 27683852.
    View in: PubMed
  24. Bove R, White CC, Fitzgerald KC, Chitnis T, Chibnik L, Ascherio A, Munger KL. Hormone therapy use and physical quality of life in postmenopausal women with multiple sclerosis. Neurology. 2016 Oct 04; 87(14):1457-1463. PMID: 27605175.
    View in: PubMed
  25. Glanz BI, Greeke E, LaRussa A, Stuart F, Rintell DJ, Chitnis T, Healy BC. Risk attitudes and risk perceptions in individuals with multiple sclerosis. Mult Scler J Exp Transl Clin. 2016 Jan-Dec; 2:2055217316665406. PMID: 28607735.
    View in: PubMed
  26. Chitnis T, Ghezzi A, Bajer-Kornek B, Boyko A, Giovannoni G, Pohl D. Pediatric multiple sclerosis: Escalation and emerging treatments. Neurology. 2016 Aug 30; 87(9 Suppl 2):S103-9. PMID: 27572854.
    View in: PubMed
  27. Tenembaum S, Chitnis T, Nakashima I, Collongues N, McKeon A, Levy M, Rostasy K. Neuromyelitis optica spectrum disorders in children and adolescents. Neurology. 2016 Aug 30; 87(9 Suppl 2):S59-66. PMID: 27572863.
    View in: PubMed
  28. Wassmer E, Chitnis T, Pohl D, Amato MP, Banwell B, Ghezzi A, Hintzen RQ, Krupp LB, Makhani N, Rostásy K, Tardieu M, Tenembaum S, Waldman A, Waubant E, Kornberg AJ. International Pediatric MS Study Group Global Members Symposium report. Neurology. 2016 Aug 30; 87(9 Suppl 2):S110-6. PMID: 27572855.
    View in: PubMed
  29. Bar-Or A, Hintzen RQ, Dale RC, Rostasy K, Brück W, Chitnis T. Immunopathophysiology of pediatric CNS inflammatory demyelinating diseases. Neurology. 2016 Aug 30; 87(9 Suppl 2):S12-9. PMID: 27572856.
    View in: PubMed
  30. Regev K, Paul A, Healy B, von Glenn F, Diaz-Cruz C, Gholipour T, Mazzola MA, Raheja R, Nejad P, Glanz BI, Kivisakk P, Chitnis T, Weiner HL, Gandhi R. Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. 2016 Oct; 3(5):e267. PMID: 27606352; PMCID: PMC4996540.
  31. Simone M, Chitnis T. Use of Disease-Modifying Therapies in Pediatric MS. Curr Treat Options Neurol. 2016 Aug; 18(8):36. PMID: 27314428.
    View in: PubMed
  32. Bove R, Chua AS, Xia Z, Chibnik L, De Jager PL, Chitnis T. Complex relation of HLA-DRB1*1501, age at menarche, and age at multiple sclerosis onset. Neurol Genet. 2016 Aug; 2(4):e88. PMID: 27504495; PMCID: PMC4962522.
  33. Belman AL, Krupp LB, Olsen CS, Rose JW, Aaen G, Benson L, Chitnis T, Gorman M, Graves J, Harris Y, Lotze T, Ness J, Rodriguez M, Tillema JM, Waubant E, Weinstock-Guttman B, Casper TC. Characteristics of Children and Adolescents With Multiple Sclerosis. Pediatrics. 2016 Jul; 138(1). PMID: 27358474; PMCID: PMC4925083 [Available on 07/01/17].
  34. Bove R, Vaughan T, Chitnis T, Wicks P, De Jager PL. Women's experiences of menopause in an online MS cohort: A case series. Mult Scler Relat Disord. 2016 Sep; 9:56-9. PMID: 27645345.
    View in: PubMed
  35. Jangi S, Gandhi R, Cox LM, Li N, von Glehn F, Yan R, Patel B, Mazzola MA, Liu S, Glanz BL, Cook S, Tankou S, Stuart F, Melo K, Nejad P, Smith K, Topçuolu BD, Holden J, Kivisäkk P, Chitnis T, De Jager PL, Quintana FJ, Gerber GK, Bry L, Weiner HL. Alterations of the human gut microbiome in multiple sclerosis. Nat Commun. 2016 Jun 28; 7:12015. PMID: 27352007; PMCID: PMC4931233.
  36. Nourbakhsh B, Graves J, Casper TC, Lulu S, Waldman A, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Ness J, Rubin J, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Barcellos L, Waubant E. Dietary salt intake and time to relapse in paediatric multiple sclerosis. J Neurol Neurosurg Psychiatry. 2016 Dec; 87(12):1350-1353. PMID: 27343226.
    View in: PubMed
  37. Bove R, Musallam A, Xia Z, Baruch N, Messina S, Healy BC, Chitnis T. Longitudinal BMI trajectories in multiple sclerosis: Sex differences in association with disease severity. Mult Scler Relat Disord. 2016 Jul; 8:136-40. PMID: 27456889.
    View in: PubMed
  38. Koelman DL, Chahin S, Mar SS, Venkatesan A, Hoganson GM, Yeshokumar AK, Barreras P, Majmudar B, Klein JP, Chitnis T, Benkeser DC, Carone M, Mateen FJ. Acute disseminated encephalomyelitis in 228 patients: A retrospective, multicenter US study. Neurology. 2016 May 31; 86(22):2085-93. PMID: 27164698.
    View in: PubMed
  39. Lee JY, Chitnis T. Pediatric Multiple Sclerosis. Semin Neurol. 2016 Apr; 36(2):148-53. PMID: 27116721.
    View in: PubMed
  40. Cavallari M, Palotai M, Glanz BI, Egorova S, Prieto JC, Healy BC, Chitnis T, Guttmann CR. Fatigue predicts disease worsening in relapsing-remitting multiple sclerosis patients. Mult Scler. 2016 Dec; 22(14):1841-1849. PMID: 26920374.
    View in: PubMed
  41. McDonald J, Graves J, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Lulu S, Ness J, Harris Y, Rubin J, Candee M, Krupp LB, Gorman M, Benson L, Rodriguez M, Chitnis T, Mar S, Barcellos LF, Laraia B, Rose J, Roalstad S, Simmons T, Casper TC, Waubant E. A case-control study of dietary salt intake in pediatric-onset multiple sclerosis. Mult Scler Relat Disord. 2016 Mar; 6:87-92. PMID: 27063630; PMCID: PMC4830915 [Available on 03/01/17].
  42. Mazzola MA, Raheja R, Murugaiyan G, Rajabi H, Kumar D, Pertel T, Regev K, Griffin R, Aly L, Kivisakk P, Nejad P, Patel B, Gwanyalla N, Hei H, Glanz B, Chitnis T, Weiner HL, Gandhi R. Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation. J Neuroinflammation. 2015 Dec 30; 12:245. PMID: 26714756; PMCID: PMC4696082.
  43. Chitnis T, Ness J, Krupp L, Waubant E, Hunt T, Olsen CS, Rodriguez M, Lotze T, Gorman M, Benson L, Belman A, Weinstock-Guttman B, Aaen G, Graves J, Patterson M, Rose JW, Casper TC. Clinical features of neuromyelitis optica in children: US Network of Pediatric MS Centers report. Neurology. 2016 Jan 19; 86(3):245-52. PMID: 26683648; PMCID: PMC4733158.
  44. Xia Z, White CC, Owen EK, Von Korff A, Clarkson SR, McCabe CA, Cimpean M, Winn PA, Hoesing A, Steele SU, Cortese IC, Chitnis T, Weiner HL, Reich DS, Chibnik LB, De Jager PL. Genes and Environment in Multiple Sclerosis project: A platform to investigate multiple sclerosis risk. Ann Neurol. 2016 Feb; 79(2):178-89. PMID: 26583565; PMCID: PMC4778957 [Available on 02/01/17].
  45. Rotstein DL, Healy BC, Malik MT, Carruthers RL, Musallam AJ, Kivisakk P, Weiner HL, Glanz B, Chitnis T. Effect of vitamin D on MS activity by disease-modifying therapy class. Neurol Neuroimmunol Neuroinflamm. 2015 Dec; 2(6):e167. PMID: 26568968; PMCID: PMC4630683.
  46. Oommen VV, Tauhid S, Healy BC, Chua AS, Malik MT, Diaz-Cruz C, Dupuy SL, Weiner HL, Chitnis T, Bakshi R. The Effect of Fingolimod on Conversion of Acute Gadolinium-Enhancing Lesions to Chronic T1 Hypointensities in Multiple Sclerosis. J Neuroimaging. 2016 Mar-Apr; 26(2):184-7. PMID: 26445919.
    View in: PubMed
  47. Bove R, Healy BC, Musallam A, Glanz BI, De Jager PL, Chitnis T. Exploration of changes in disability after menopause in a longitudinal multiple sclerosis cohort. Mult Scler. 2016 Jun; 22(7):935-43. PMID: 26447063; PMCID: PMC4824677 [Available on 06/01/17].
  48. Chua AS, Glanz BI, Guarino AJ, Cook SL, Greeke EE, Little GE, Chitnis T, Healy BC. Patient-reported outcomes in multiple sclerosis: Relationships among existing scales and the development of a brief measure. Mult Scler Relat Disord. 2015 Nov; 4(6):598-606. PMID: 26590669.
    View in: PubMed
  49. Bove R, Malik MT, Diaz-Cruz C, Chua A, Saraceno TJ, Bargiela D, Greeke E, Glanz BI, Healy BC, Chitnis T. The 2D:4D ratio, a proxy for prenatal androgen levels, differs in men with and without MS. Neurology. 2015 Oct 06; 85(14):1209-13. PMID: 26341868; PMCID: PMC4607599 [Available on 10/06/16].
  50. Tauhid S, Chu R, Sasane R, Glanz BI, Neema M, Miller JR, Kim G, Signorovitch JE, Healy BC, Chitnis T, Weiner HL, Bakshi R. Brain MRI lesions and atrophy are associated with employment status in patients with multiple sclerosis. J Neurol. 2015 Nov; 262(11):2425-32. PMID: 26205635; PMCID: PMC4639581.
  51. Melamed E, Levy M, Waters PJ, Sato DK, Bennett JL, John GR, Hooper DC, Saiz A, Bar-Or A, Kim HJ, Pandit L, Leite MI, Asgari N, Kissani N, Hintzen R, Marignier R, Jarius S, Marcelletti J, Smith TJ, Yeaman MR, Han MH, Aktas O, Apiwattanakul M, Banwell B, Bichuetti D, Broadley S, Cabre P, Chitnis T, De Seze J, Fujihara K, Greenberg B, Hellwig K, Iorio R, Jarius S, Klawiter E, Kleiter I, Lana-Peixoto M, O'Connor K, Palace J, Paul F, Prayoonwiwat N, Ruprecht K, Stuve O, Tedder T, Tenembaum S, Garrahan JP, Aires B, van Herle K, van Pelt D, Villoslada P, Waubant E, Weinshenker B, Wingerchuk D, Würfel J, Zamvil S. Update on biomarkers in neuromyelitis optica. Neurol Neuroimmunol Neuroinflamm. 2015 Aug; 2(4):e134. PMID: 26236760; PMCID: PMC4516398.
  52. Liu J, Brodley CE, Healy BC, Chitnis T. Removing confounding factors via constraint-based clustering: An application to finding homogeneous groups of multiple sclerosis patients. Artif Intell Med. 2015 Oct; 65(2):79-88. PMID: 26253753.
    View in: PubMed
  53. Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC. Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models. Neuroimage Clin. 2015; 8:606-10. PMID: 26199872; PMCID: PMC4506959.
  54. Kremer S, Renard F, Achard S, Lana-Peixoto MA, Palace J, Asgari N, Klawiter EC, Tenembaum SN, Banwell B, Greenberg BM, Bennett JL, Levy M, Villoslada P, Saiz A, Fujihara K, Chan KH, Schippling S, Paul F, Kim HJ, de Seze J, Wuerfel JT, Cabre P, Marignier R, Tedder T, van Pelt D, Broadley S, Chitnis T, Wingerchuk D, Pandit L, Leite MI, Apiwattanakul M, Kleiter I, Prayoonwiwat N, Han M, Hellwig K, van Herle K, John G, Hooper DC, Nakashima I, Sato D, Yeaman MR, Waubant E, Zamvil S, Stüve O, Aktas O, Smith TJ, Jacob A, O'Connor K. Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder. JAMA Neurol. 2015 Jul; 72(7):815-22. PMID: 26010909; PMCID: PMC4828237.
  55. Wingerchuk DM, Banwell B, Bennett JL, Cabre P, Carroll W, Chitnis T, de Seze J, Fujihara K, Greenberg B, Jacob A, Jarius S, Lana-Peixoto M, Levy M, Simon JH, Tenembaum S, Traboulsee AL, Waters P, Wellik KE, Weinshenker BG. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology. 2015 Jul 14; 85(2):177-89. PMID: 26092914; PMCID: PMC4515040.
  56. Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC. Using multiple imputation to efficiently correct cerebral MRI whole brain lesion and atrophy data in patients with multiple sclerosis. Neuroimage. 2015 Oct 01; 119:81-8. PMID: 26093330.
    View in: PubMed
  57. Baruch NF, O'Donnell EH, Glanz BI, Benedict RH, Musallam AJ, Healy BC, Rintell D, Chitnis T. Cognitive and patient-reported outcomes in adults with pediatric-onset multiple sclerosis. Mult Scler. 2016 Mar; 22(3):354-61. PMID: 26041802.
    View in: PubMed
  58. Fernandez-Carbonell C, Vargas-Lowy D, Musallam A, Healy B, McLaughlin K, Wucherpfennig KW, Chitnis T. Clinical and MRI phenotype of children with MOG antibodies. Mult Scler. 2016 Feb; 22(2):174-84. PMID: 26041801; PMCID: PMC4669239 [Available on 02/01/17].
  59. Pandit L, Asgari N, Apiwattanakul M, Palace J, Paul F, Leite MI, Kleiter I, Chitnis T. Demographic and clinical features of neuromyelitis optica: A review. Mult Scler. 2015 Jun; 21(7):845-53. PMID: 25921037; PMCID: PMC4463026.
  60. Engler D, Chitnis T, Healy B. Joint assessment of dependent discrete disease state processes. Stat Methods Med Res. 2017 Jun; 26(3):1182-1198. PMID: 25698716.
    View in: PubMed
  61. Rotstein DL, Healy BC, Malik MT, Chitnis T, Weiner HL. Evaluation of no evidence of disease activity in a 7-year longitudinal multiple sclerosis cohort. JAMA Neurol. 2015 Feb; 72(2):152-8. PMID: 25531931.
    View in: PubMed
  62. Bove R, Healy BC, Secor E, Vaughan T, Katic B, Chitnis T, Wicks P, De Jager PL. Patients report worse MS symptoms after menopause: findings from an online cohort. Mult Scler Relat Disord. 2015 Jan; 4(1):18-24. PMID: 25787049.
    View in: PubMed
  63. Chitnis T, Gorman MP. Impact of MS during the critical window of brain development. Neurology. 2014 Dec 02; 83(23):2106-7. PMID: 25378681.
    View in: PubMed
  64. Graves J, Grandhe S, Weinfurtner K, Krupp L, Belman A, Chitnis T, Ness J, Weinstock-Guttman B, Gorman M, Patterson M, Rodriguez M, Lotze T, Aaen G, Mowry EM, Rose JW, Simmons T, Casper TC, James J, Waubant E. Protective environmental factors for neuromyelitis optica. Neurology. 2014 Nov 18; 83(21):1923-9. PMID: 25339213; PMCID: PMC4248458.
  65. Bakshi R, Neema M, Tauhid S, Healy BC, Glanz BI, Kim G, Miller J, Berkowitz JL, Bove R, Houtchens MK, Severson C, Stankiewicz JM, Stazzone L, Chitnis T, Guttmann CR, Weiner HL, Ceccarelli A. An expanded composite scale of MRI-defined disease severity in multiple sclerosis: MRDSS2. Neuroreport. 2014 Oct 01; 25(14):1156-61. PMID: 25100554; PMCID: PMC4166046.
  66. Casper TC, Rose JW, Roalstad S, Waubant E, Aaen G, Belman A, Chitnis T, Gorman M, Krupp L, Lotze TE, Ness J, Patterson M, Rodriguez M, Weinstock-Guttman B, Browning B, Graves J, Tillema JM, Benson L, Harris Y. The US Network of Pediatric Multiple Sclerosis Centers: Development, Progress, and Next Steps. J Child Neurol. 2015 Sep; 30(10):1381-7. PMID: 25270659; PMCID: PMC4379142.
  67. Raghavan K, Healy BC, Carruthers RL, Chitnis T. Progression rates and sample size estimates for PPMS based on the CLIMB study population. Mult Scler. 2015 Feb; 21(2):180-8. PMID: 25070676.
    View in: PubMed
  68. Chitnis T, Waubant E. B-cell depletion in children with neuroimmunologic conditions: the learning curve. Neurology. 2014 Jul 08; 83(2):111-2. PMID: 24920852.
    View in: PubMed
  69. Carruthers RL, Rotstein DL, Healy BC, Chitnis T, Weiner HL, Buckle GJ. An observational comparison of natalizumab vs. fingolimod using JCV serology to determine therapy. Mult Scler. 2014 Sep; 20(10):1381-90. PMID: 24852928.
    View in: PubMed
  70. Malik MT, Healy BC, Benson LA, Kivisakk P, Musallam A, Weiner HL, Chitnis T. Factors associated with recovery from acute optic neuritis in patients with multiple sclerosis. Neurology. 2014 Jun 17; 82(24):2173-9. PMID: 24850491; PMCID: PMC4113460.
  71. Bove R, Musallam A, Healy BC, Raghavan K, Glanz BI, Bakshi R, Weiner H, De Jager PL, Miller KK, Chitnis T. Low testosterone is associated with disability in men with multiple sclerosis. Mult Scler. 2014 Oct; 20(12):1584-92. PMID: 24710799; PMCID: PMC4188801.
  72. Charvet LE, O'Donnell EH, Belman AL, Chitnis T, Ness JM, Parrish J, Patterson M, Rodriguez M, Waubant E, Weinstock-Guttman B, Krupp LB. Longitudinal evaluation of cognitive functioning in pediatric multiple sclerosis: report from the US Pediatric Multiple Sclerosis Network. Mult Scler. 2014 Oct; 20(11):1502-10. PMID: 24687807; PMCID: PMC4192109.
  73. Bove R, Chitnis T. The role of gender and sex hormones in determining the onset and outcome of multiple sclerosis. Mult Scler. 2014 Apr; 20(5):520-6. PMID: 24561324.
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  74. Linnoila J, Chitnis T. Balo concentric sclerosis in children: a case series. J Child Neurol. 2014 May; 29(5):603-7. PMID: 24423690.
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  75. Glanz BI, Musallam A, Rintell DJ, Chitnis T, Weiner HL, Healy BC. Treatment satisfaction in multiple sclerosis. Int J MS Care. 2014; 16(2):68-75. PMID: 25061430; PMCID: PMC4106393.
  76. Chitnis T, Guttmann CR, Zaitsev A, Musallam A, Weinstock-Guttman B, Yeh A, Rodriguez M, Ness J, Gorman MP, Healy BC, Kuntz N, Chabas D, Strober JB, Waubant E, Krupp L, Pelletier D, Erickson B, Bergsland N, Zivadinov R. Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study. BMC Neurol. 2013 Nov 13; 13:173. PMID: 24225378; PMCID: PMC3832402.
  77. Messina S, Vargas-Lowy D, Musallam A, Healy BC, Kivisakk P, Gandhi R, Bove R, Gholipour T, Khoury S, Weiner HL, Chitnis T. Increased leptin and A-FABP levels in relapsing and progressive forms of MS. BMC Neurol. 2013 Nov 11; 13:172. PMID: 24215402; PMCID: PMC3829106.
  78. Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL. Modeling disease severity in multiple sclerosis using electronic health records. PLoS One. 2013; 8(11):e78927. PMID: 24244385; PMCID: PMC3823928.
  79. Carruthers RL, Chitnis T, Healy BC. Modeling probability of additional cases of natalizumab-associated JCV sero-negative progressive multifocal leukoencephalopathy. Mult Scler. 2014 May; 20(6):757-60. PMID: 24189572.
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  80. Ottoboni L, Frohlich IY, Lee M, Healy BC, Keenan BT, Xia Z, Chitnis T, Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, De Jager PL. Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus. Neurology. 2013 Nov 26; 81(22):1891-9. PMID: 24174586; PMCID: PMC3843384.
  81. Bove R, Chitnis T, Houtchens M. Menopause in multiple sclerosis: therapeutic considerations. J Neurol. 2014 Jul; 261(7):1257-68. PMID: 24101131.
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  82. Fernández Carbonell C, Benson L, Rintell D, Prince J, Chitnis T. Functional relapses in pediatric multiple sclerosis. J Child Neurol. 2014 Jul; 29(7):943-6. PMID: 24065582.
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  83. Kivisäkk P, Healy BC, Francois K, Gandhi R, Gholipour T, Egorova S, Sevdalinova V, Quintana F, Chitnis T, Weiner HL, Khoury SJ. Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development. Mult Scler. 2014 Apr; 20(4):438-44. PMID: 24005026.
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  84. Chitnis T. Paediatric MS is the same disease as adult MS: no. Mult Scler. 2013 Sep; 19(10):1255-6. PMID: 23996596.
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  85. Chitnis T, Khoury SJ. Sex influences in autoimmune disease. Clin Immunol. 2013 Nov; 149(2):169. PMID: 24012474.
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  86. Chitnis T. Pediatric demyelinating diseases. Continuum (Minneap Minn). 2013 Aug; 19(4 Multiple Sclerosis):1023-45. PMID: 23917099.
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  87. Benson LA, Healy BC, Gorman MP, Baruch NF, Gholipour T, Musallam A, Chitnis T. Elevated relapse rates in pediatric compared to adult MS persist for at least 6 years. Mult Scler Relat Disord. 2014 Mar; 3(2):186-93. PMID: 25878006.
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  88. Gandhi R, Healy B, Gholipour T, Egorova S, Musallam A, Hussain MS, Nejad P, Patel B, Hei H, Khoury S, Quintana F, Kivisakk P, Chitnis T, Weiner HL. Circulating microRNAs as biomarkers for disease staging in multiple sclerosis. Ann Neurol. 2013 Jun; 73(6):729-40. PMID: 23494648.
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  89. Bove R, Musallam A, Healy BC, Houtchens M, Glanz BI, Khoury S, Guttmann CR, De Jager PL, Chitnis T. No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50. BMC Neurol. 2013 Jul 03; 13:73. PMID: 23822612; PMCID: PMC3707791.
  90. Fernández Carbonell C, Chitnis T. Inflammatory demyelinating diseases in children: an update. Minerva Pediatr. 2013 Jun; 65(3):307-23. PMID: 23685382.
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  91. Van Haren K, Tomooka BH, Kidd BA, Banwell B, Bar-Or A, Chitnis T, Tenembaum SN, Pohl D, Rostasy K, Dale RC, O'Connor KC, Hafler DA, Steinman L, Robinson WH. Serum autoantibodies to myelin peptides distinguish acute disseminated encephalomyelitis from relapsing-remitting multiple sclerosis. Mult Scler. 2013 Nov; 19(13):1726-33. PMID: 23612879; PMCID: PMC4411183.
  92. Krupp LB, Tardieu M, Amato MP, Banwell B, Chitnis T, Dale RC, Ghezzi A, Hintzen R, Kornberg A, Pohl D, Rostasy K, Tenembaum S, Wassmer E. International Pediatric Multiple Sclerosis Study Group criteria for pediatric multiple sclerosis and immune-mediated central nervous system demyelinating disorders: revisions to the 2007 definitions. Mult Scler. 2013 Sep; 19(10):1261-7. PMID: 23572237.
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  93. Chitnis T. Role of puberty in multiple sclerosis risk and course. Clin Immunol. 2013 Nov; 149(2):192-200. PMID: 23623473.
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  94. Bove R, Chitnis T. Sexual disparities in the incidence and course of MS. Clin Immunol. 2013 Nov; 149(2):201-10. PMID: 23608496.
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  95. Bove R, Secor E, Healy BC, Musallam A, Vaughan T, Glanz BI, Greeke E, Weiner HL, Chitnis T, Wicks P, De Jager PL. Evaluation of an online platform for multiple sclerosis research: patient description, validation of severity scale, and exploration of BMI effects on disease course. PLoS One. 2013; 8(3):e59707. PMID: 23527256; PMCID: PMC3603866.
  96. Chitnis T, Tardieu M, Amato MP, Banwell B, Bar-Or A, Ghezzi A, Kornberg A, Krupp LB, Pohl D, Rostasy K, Tenembaum S, Waubant E, Wassmer E. International Pediatric MS Study Group Clinical Trials Summit: meeting report. Neurology. 2013 Mar 19; 80(12):1161-8. PMID: 23509048; PMCID: PMC3662305.
  97. Healy BC, Engler D, Glanz B, Musallam A, Chitnis T. Assessment of definitions of sustained disease progression in relapsing-remitting multiple sclerosis. Mult Scler Int. 2013; 2013:189624. PMID: 23555057; PMCID: PMC3608311.
  98. Chitnis T. Disease-modifying therapy of pediatric multiple sclerosis. Neurotherapeutics. 2013 Jan; 10(1):89-96. PMID: 23224690; PMCID: PMC3557355.
  99. Vargas-Lowy D, Kivisäkk P, Gandhi R, Raddassi K, Soltany P, Gorman MP, Khoury SJ, Chitnis T. Increased Th17 response to myelin peptides in pediatric MS. Clin Immunol. 2013 Mar; 146(3):176-84. PMID: 23352968.
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  100. Waubant E, Mowry EM, Krupp L, Chitnis T, Yeh EA, Kuntz N, Ness J, Belman A, Milazzo M, Gorman M, Weinstock-Guttman B, Rodriguez M, James JA. Antibody response to common viruses and human leukocyte antigen-DRB1 in pediatric multiple sclerosis. Mult Scler. 2013 Jun; 19(7):891-5. PMID: 23232601; PMCID: PMC3665694.
  101. Julian L, Serafin D, Charvet L, Ackerson J, Benedict R, Braaten E, Brown T, O'Donnell E, Parrish J, Preston T, Zaccariello M, Belman A, Chitnis T, Gorman M, Ness J, Patterson M, Rodriguez M, Waubant E, Weinstock-Guttman B, Yeh A, Krupp LB. Cognitive impairment occurs in children and adolescents with multiple sclerosis: results from a United States network. J Child Neurol. 2013 Jan; 28(1):102-7. PMID: 23155206; PMCID: PMC3652651.
  102. Glanz BI, Dégano IR, Rintell DJ, Chitnis T, Weiner HL, Healy BC. Work productivity in relapsing multiple sclerosis: associations with disability, depression, fatigue, anxiety, cognition, and health-related quality of life. Value Health. 2012 Dec; 15(8):1029-35. PMID: 23244804.
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  103. Vargas-Lowy D, Chitnis T. Pathogenesis of pediatric multiple sclerosis. J Child Neurol. 2012 Nov; 27(11):1394-407. PMID: 22952316.
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  104. Vishwas MS, Healy BC, Pienaar R, Gorman MP, Grant PE, Chitnis T. Diffusion tensor analysis of pediatric multiple sclerosis and clinically isolated syndromes. AJNR Am J Neuroradiol. 2013 Feb; 34(2):417-23. PMID: 22859275.
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  105. Ceccarelli A, Jackson JS, Tauhid S, Arora A, Gorky J, Dell'Oglio E, Bakshi A, Chitnis T, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R, Neema M. The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis. AJNR Am J Neuroradiol. 2012 Sep; 33(8):1579-85. PMID: 22460341; PMCID: PMC3425668.
  106. Bove RM, Healy B, Augustine A, Musallam A, Gholipour T, Chitnis T. Effect of gender on late-onset multiple sclerosis. Mult Scler. 2012 Oct; 18(10):1472-9. PMID: 22383227.
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  107. Healy BC, Degano IR, Schreck A, Rintell D, Weiner H, Chitnis T, Glanz BI. The impact of a recent relapse on patient-reported outcomes in subjects with multiple sclerosis. Qual Life Res. 2012 Dec; 21(10):1677-84. PMID: 22237991.
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  108. Chitnis T, Hollmann TJ. CADASIL mutation and Balo concentric sclerosis: a link between demyelination and ischemia? Neurology. 2012 Jan 17; 78(3):221-3. PMID: 22218279; PMCID: PMC3466606.
  109. Gorman MP, Tillema JM, Ciliax AM, Guttmann CR, Chitnis T. Daclizumab use in patients with pediatric multiple sclerosis. Arch Neurol. 2012 Jan; 69(1):78-81. PMID: 22232346.
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  110. Moodie J, Healy BC, Buckle GJ, Gauthier SA, Glanz BI, Arora A, Ceccarelli A, Tauhid S, Han XM, Venkataraman A, Chitnis T, Khoury SJ, Guttmann CR, Weiner HL, Neema M, Bakshi R. Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study. J Neurol Sci. 2012 Apr 15; 315(1-2):49-54. PMID: 22209496; PMCID: PMC3319060.
  111. Chitnis T, Tenembaum S, Banwell B, Krupp L, Pohl D, Rostasy K, Yeh EA, Bykova O, Wassmer E, Tardieu M, Kornberg A, Ghezzi A. Consensus statement: evaluation of new and existing therapeutics for pediatric multiple sclerosis. Mult Scler. 2012 Jan; 18(1):116-27. PMID: 22146610.
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  112. Glanz BI, Healy BC, Hviid LE, Chitnis T, Weiner HL. Cognitive deterioration in patients with early multiple sclerosis: a 5-year study. J Neurol Neurosurg Psychiatry. 2012 Jan; 83(1):38-43. PMID: 21746743.
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  113. Mirzaei F, Michels KB, Munger K, O'Reilly E, Chitnis T, Forman MR, Giovannucci E, Rosner B, Ascherio A. Gestational vitamin D and the risk of multiple sclerosis in offspring. Ann Neurol. 2011 Jul; 70(1):30-40. PMID: 21786297; PMCID: PMC3205990.
  114. Gholipour T, Healy B, Baruch NF, Weiner HL, Chitnis T. Demographic and clinical characteristics of malignant multiple sclerosis. Neurology. 2011 Jun 07; 76(23):1996-2001. PMID: 21646626.
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  115. Waubant E, Mowry EM, Krupp L, Chitnis T, Yeh EA, Kuntz N, Ness J, Chabas D, Strober J, McDonald J, Belman A, Milazzo M, Gorman M, Weinstock-Guttman B, Rodriguez M, Oksenberg JR, James JA. Common viruses associated with lower pediatric multiple sclerosis risk. Neurology. 2011 Jun 07; 76(23):1989-95. PMID: 21646624; PMCID: PMC3109881.
  116. Chitnis T, Krupp L, Yeh A, Rubin J, Kuntz N, Strober JB, Chabas D, Weinstock-Guttmann B, Ness J, Rodriguez M, Waubant E. Pediatric multiple sclerosis. Neurol Clin. 2011 May; 29(2):481-505. PMID: 21439455.
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  117. Healy B, Chitnis T, Engler D. Improving power to detect disease progression in multiple sclerosis through alternative analysis strategies. J Neurol. 2011 Oct; 258(10):1812-9. PMID: 21472497.
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  118. Liguori M, Meier DS, Hildenbrand P, Healy BC, Chitnis T, Baruch NF, Khoury SJ, Weiner HL, Bakshi R, Barkhof F, Guttmann CR. One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2011 Oct; 82(10):1125-31. PMID: 21429902.
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  119. Hviid LE, Healy BC, Rintell DJ, Chitnis T, Weiner HL, Glanz BI. Patient reported outcomes in benign multiple sclerosis. Mult Scler. 2011 Jul; 17(7):876-84. PMID: 21372114.
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  120. Imitola J, Côté D, Rasmussen S, Xie XS, Liu Y, Chitnis T, Sidman RL, Lin CP, Khoury SJ. Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice. J Biomed Opt. 2011 Feb; 16(2):021109. PMID: 21361672; PMCID: PMC3061329.
  121. Healy BC, Engler D, Gholipour T, Weiner H, Bakshi R, Chitnis T. Accounting for disease modifying therapy in models of clinical progression in multiple sclerosis. J Neurol Sci. 2011 Apr 15; 303(1-2):109-13. PMID: 21251671.
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  122. Yeh EA, Waubant E, Krupp LB, Ness J, Chitnis T, Kuntz N, Ramanathan M, Belman A, Chabas D, Gorman MP, Rodriguez M, Rinker JR, Weinstock-Guttman B. Multiple sclerosis therapies in pediatric patients with refractory multiple sclerosis. Arch Neurol. 2011 Apr; 68(4):437-44. PMID: 21149803.
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  123. Xia Z, Chibnik LB, Glanz BI, Liguori M, Shulman JM, Tran D, Khoury SJ, Chitnis T, Holyoak T, Weiner HL, Guttmann CR, De Jager PL. A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis. PLoS One. 2010 Nov 30; 5(11):e14169. PMID: 21152065; PMCID: PMC2994939.
  124. Gross R, Healy BC, Cepok S, Chitnis T, Khoury SJ, Hemmer B, Weiner HL, Hafler DA, De Jager PL. Population structure and HLA DRB1 1501 in the response of subjects with multiple sclerosis to first-line treatments. J Neuroimmunol. 2011 Apr; 233(1-2):168-74. PMID: 21115201.
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  125. Munger KL, Chitnis T, Frazier AL, Giovannucci E, Spiegelman D, Ascherio A. Dietary intake of vitamin D during adolescence and risk of multiple sclerosis. J Neurol. 2011 Mar; 258(3):479-85. PMID: 20945071; PMCID: PMC3077931.
  126. Healy BC, Glanz BI, Stankiewicz J, Buckle G, Weiner H, Chitnis T. A method for evaluating treatment switching criteria in multiple sclerosis. Mult Scler. 2010 Dec; 16(12):1483-9. PMID: 20736245.
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  127. Healy BC, Liguori M, Tran D, Chitnis T, Glanz B, Wolfish C, Gauthier S, Buckle G, Houtchens M, Stazzone L, Khoury S, Hartzmann R, Fernandez-Vina M, Hafler DA, Weiner HL, Guttmann CR, De Jager PL. HLA B*44: protective effects in MS susceptibility and MRI outcome measures. Neurology. 2010 Aug 17; 75(7):634-40. PMID: 20713950; PMCID: PMC2931768.
  128. Kuntz NL, Chabas D, Weinstock-Guttman B, Chitnis T, Yeh EA, Krupp L, Ness J, Rodriguez M, Waubant E. Treatment of multiple sclerosis in children and adolescents. Expert Opin Pharmacother. 2010 Mar; 11(4):505-20. PMID: 20163265.
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  129. Liu Y, Bando Y, Vargas-Lowy D, Elyaman W, Khoury SJ, Huang T, Reif K, Chitnis T. CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis. J Neurosci. 2010 Feb 10; 30(6):2025-38. PMID: 20147531; PMCID: PMC2837938.
  130. Chabas D, Ness J, Belman A, Yeh EA, Kuntz N, Gorman MP, Strober JB, De Kouchkovsky I, McCulloch C, Chitnis T, Rodriguez M, Weinstock-Guttman B, Krupp LB, Waubant E. Younger children with MS have a distinct CSF inflammatory profile at disease onset. Neurology. 2010 Feb 02; 74(5):399-405. PMID: 20124205; PMCID: PMC2816008.
  131. Munger KL, Chitnis T, Ascherio A. Body size and risk of MS in two cohorts of US women. Neurology. 2009 Nov 10; 73(19):1543-50. PMID: 19901245; PMCID: PMC2777074.
  132. Vishwas MS, Chitnis T, Pienaar R, Healy BC, Grant PE. Tract-based analysis of callosal, projection, and association pathways in pediatric patients with multiple sclerosis: a preliminary study. AJNR Am J Neuroradiol. 2010 Jan; 31(1):121-8. PMID: 19850763.
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  133. Yeh EA, Chitnis T, Krupp L, Ness J, Chabas D, Kuntz N, Waubant E. Pediatric multiple sclerosis. Nat Rev Neurol. 2009 Nov; 5(11):621-31. PMID: 19826402.
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  134. Sampat MP, Berger AM, Healy BC, Hildenbrand P, Vass J, Meier DS, Chitnis T, Weiner HL, Bakshi R, Guttmann CR. Regional white matter atrophy--based classification of multiple sclerosis in cross-sectional and longitudinal data. AJNR Am J Neuroradiol. 2009 Oct; 30(9):1731-9. PMID: 19696139; PMCID: PMC2821733.
  135. McLaughlin KA, Chitnis T, Newcombe J, Franz B, Kennedy J, McArdel S, Kuhle J, Kappos L, Rostasy K, Pohl D, Gagne D, Ness JM, Tenembaum S, O'Connor KC, Viglietta V, Wong SJ, Tavakoli NP, de Seze J, Idrissova Z, Khoury SJ, Bar-Or A, Hafler DA, Banwell B, Wucherpfennig KW. Age-dependent B cell autoimmunity to a myelin surface antigen in pediatric multiple sclerosis. J Immunol. 2009 Sep 15; 183(6):4067-76. PMID: 19687098; PMCID: PMC2795331.
  136. Gardener H, Munger KL, Chitnis T, Michels KB, Spiegelman D, Ascherio A. Prenatal and perinatal factors and risk of multiple sclerosis. Epidemiology. 2009 Jul; 20(4):611-8. PMID: 19333127; PMCID: PMC3132937.
  137. Healy BC, Ali EN, Guttmann CR, Chitnis T, Glanz BI, Buckle G, Houtchens M, Stazzone L, Moodie J, Berger AM, Duan Y, Bakshi R, Khoury S, Weiner H, Ascherio A. Smoking and disease progression in multiple sclerosis. Arch Neurol. 2009 Jul; 66(7):858-64. PMID: 19597087; PMCID: PMC2754172.
  138. Makhani N, Gorman MP, Branson HM, Stazzone L, Banwell BL, Chitnis T. Cyclophosphamide therapy in pediatric multiple sclerosis. Neurology. 2009 Jun 16; 72(24):2076-82. PMID: 19439723; PMCID: PMC2923592.
  139. Gardener H, Munger K, Chitnis T, Spiegelman D, Ascherio A. The relationship between handedness and risk of multiple sclerosis. Mult Scler. 2009 May; 15(5):587-92. PMID: 19389750; PMCID: PMC2771381.
  140. Stankiewicz JM, Neema M, Alsop DC, Healy BC, Arora A, Buckle GJ, Chitnis T, Guttmann CR, Hackney D, Bakshi R. Spinal cord lesions and clinical status in multiple sclerosis: A 1.5 T and 3 T MRI study. J Neurol Sci. 2009 Apr 15; 279(1-2):99-105. PMID: 19178916; PMCID: PMC2679653.
  141. Chitnis T, Glanz B, Jaffin S, Healy B. Demographics of pediatric-onset multiple sclerosis in an MS center population from the Northeastern United States. Mult Scler. 2009 May; 15(5):627-31. PMID: 19299440.
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  142. Chitnis T, Pirko I. Sensitivity vs specificity: progress and pitfalls in defining MRI criteria for pediatric MS. Neurology. 2009 Mar 17; 72(11):952-3. PMID: 19289735.
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  143. Gorman MP, Healy BC, Polgar-Turcsanyi M, Chitnis T. Increased relapse rate in pediatric-onset compared with adult-onset multiple sclerosis. Arch Neurol. 2009 Jan; 66(1):54-9. PMID: 19139299.
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  144. Wang Y, Evans JT, Rodriguez F, Fields P, Mueller C, Chitnis T, Khoury SJ, Bynoe MS. A tale of two STAT6 knock out mice in the induction of experimental autoimmune encephalomyelitis. J Neuroimmunol. 2009 Jan 03; 206(1-2):76-85. PMID: 19100630; PMCID: PMC2762219.
  145. Elyaman W, Kivisäkk P, Reddy J, Chitnis T, Raddassi K, Imitola J, Bradshaw E, Kuchroo VK, Yagita H, Sayegh MH, Khoury SJ. Distinct functions of autoreactive memory and effector CD4+ T cells in experimental autoimmune encephalomyelitis. Am J Pathol. 2008 Aug; 173(2):411-22. PMID: 18583313; PMCID: PMC2475778.
  146. Chitnis T, Imitola J, Wang Y, Elyaman W, Chawla P, Sharuk M, Raddassi K, Bronson RT, Khoury SJ. Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration. Am J Pathol. 2007 May; 170(5):1695-712. PMID: 17456775; PMCID: PMC1854964.
  147. Pohl D, Waubant E, Banwell B, Chabas D, Chitnis T, Weinstock-Guttman B, Tenembaum S. Treatment of pediatric multiple sclerosis and variants. Neurology. 2007 Apr 17; 68(16 Suppl 2):S54-65. PMID: 17438239.
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  148. Belman AL, Chitnis T, Renoux C, Waubant E. Challenges in the classification of pediatric multiple sclerosis and future directions. Neurology. 2007 Apr 17; 68(16 Suppl 2):S70-4. PMID: 17438242.
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  149. Tenembaum S, Chitnis T, Ness J, Hahn JS. Acute disseminated encephalomyelitis. Neurology. 2007 Apr 17; 68(16 Suppl 2):S23-36. PMID: 17438235.
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  150. O'Connor KC, McLaughlin KA, De Jager PL, Chitnis T, Bettelli E, Xu C, Robinson WH, Cherry SV, Bar-Or A, Banwell B, Fukaura H, Fukazawa T, Tenembaum S, Wong SJ, Tavakoli NP, Idrissova Z, Viglietta V, Rostasy K, Pohl D, Dale RC, Freedman M, Steinman L, Buckle GJ, Kuchroo VK, Hafler DA, Wucherpfennig KW. Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein. Nat Med. 2007 Feb; 13(2):211-7. PMID: 17237795; PMCID: PMC3429369.
  151. Chitnis T. The role of CD4 T cells in the pathogenesis of multiple sclerosis. Int Rev Neurobiol. 2007; 79:43-72. PMID: 17531837.
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  152. Chitnis T. Pediatric multiple sclerosis. Neurologist. 2006 Nov; 12(6):299-310. PMID: 17122726.
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  153. Kaneko S, Wang J, Kaneko M, Yiu G, Hurrell JM, Chitnis T, Khoury SJ, He Z. Protecting axonal degeneration by increasing nicotinamide adenine dinucleotide levels in experimental autoimmune encephalomyelitis models. J Neurosci. 2006 Sep 20; 26(38):9794-804. PMID: 16988050.
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  154. Zhu B, Guleria I, Khosroshahi A, Chitnis T, Imitola J, Azuma M, Yagita H, Sayegh MH, Khoury SJ. Differential role of programmed death-ligand 1 [corrected] and programmed death-ligand 2 [corrected] in regulating the susceptibility and chronic progression of experimental autoimmune encephalomyelitis. J Immunol. 2006 Mar 15; 176(6):3480-9. PMID: 16517716.
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  155. Imitola J, Chitnis T, Khoury SJ. Insights into the molecular pathogenesis of progression in multiple sclerosis: potential implications for future therapies. Arch Neurol. 2006 Jan; 63(1):25-33. PMID: 16401734.
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  156. Chitnis T, Imitola J, Khoury SJ. Therapeutic strategies to prevent neurodegeneration and promote regeneration in multiple sclerosis. Curr Drug Targets Immune Endocr Metabol Disord. 2005 Mar; 5(1):11-26. PMID: 15777201.
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  157. Imitola J, Chitnis T, Khoury SJ. Cytokines in multiple sclerosis: from bench to bedside. Pharmacol Ther. 2005 May; 106(2):163-77. PMID: 15866318.
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  158. Holsti MA, Chitnis T, Panzo RJ, Bronson RT, Yagita H, Sayegh MH, Tzianabos AO. Regulation of postsurgical fibrosis by the programmed death-1 inhibitory pathway. J Immunol. 2004 May 01; 172(9):5774-81. PMID: 15100324.
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  159. Chitnis T, Salama AD, Grusby MJ, Sayegh MH, Khoury SJ. Defining Th1 and Th2 immune responses in a reciprocal cytokine environment in vivo. J Immunol. 2004 Apr 01; 172(7):4260-5. PMID: 15034039.
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  160. Chitnis T, Khoury SJ. Role of costimulatory pathways in the pathogenesis of multiple sclerosis and experimental autoimmune encephalomyelitis. J Allergy Clin Immunol. 2003 Nov; 112(5):837-49; quiz 850. PMID: 14610467.
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  161. Najafian N, Chitnis T, Salama AD, Zhu B, Benou C, Yuan X, Clarkson MR, Sayegh MH, Khoury SJ. Regulatory functions of CD8+CD28- T cells in an autoimmune disease model. J Clin Invest. 2003 Oct; 112(7):1037-48. PMID: 14523041; PMCID: PMC198520.
  162. Salama AD, Chitnis T, Imitola J, Ansari MJ, Akiba H, Tushima F, Azuma M, Yagita H, Sayegh MH, Khoury SJ. Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis. J Exp Med. 2003 Jul 07; 198(1):71-8. PMID: 12847138; PMCID: PMC2196082.
  163. Ansari MJ, Salama AD, Chitnis T, Smith RN, Yagita H, Akiba H, Yamazaki T, Azuma M, Iwai H, Khoury SJ, Auchincloss H, Sayegh MH. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med. 2003 Jul 07; 198(1):63-9. PMID: 12847137; PMCID: PMC2196083.
  164. Murphy B, Yu J, Jiao Q, Lin M, Chitnis T, Sayegh MH. A novel mechanism for the immunomodulatory functions of class II MHC-derived peptides. J Am Soc Nephrol. 2003 Apr; 14(4):1053-65. PMID: 12660341.
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  165. O'Connor KC, Chitnis T, Griffin DE, Piyasirisilp S, Bar-Or A, Khoury S, Wucherpfennig KW, Hafler DA. Myelin basic protein-reactive autoantibodies in the serum and cerebrospinal fluid of multiple sclerosis patients are characterized by low-affinity interactions. J Neuroimmunol. 2003 Mar; 136(1-2):140-8. PMID: 12620653.
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  166. Chung DR, Kasper DL, Panzo RJ, Chitnis T, Grusby MJ, Sayegh MH, Tzianabos AO, Chtinis T. CD4+ T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism. J Immunol. 2003 Feb 15; 170(4):1958-63. PMID: 12574364.
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  167. Chitnis T, Khoury SJ. 20. Immunologic neuromuscular disorders. J Allergy Clin Immunol. 2003 Feb; 111(2 Suppl):S659-68. PMID: 12592311.
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  168. Chitnis T, Khoury SJ. Cytokine shifts and tolerance in experimental autoimmune encephalomyelitis. Immunol Res. 2003; 28(3):223-39. PMID: 14713716.
    View in: PubMed
  169. Chung DR, Chitnis T, Panzo RJ, Kasper DL, Sayegh MH, Tzianabos AO. CD4+ T cells regulate surgical and postinfectious adhesion formation. J Exp Med. 2002 Jun 03; 195(11):1471-8. PMID: 12045245; PMCID: PMC2193541.
  170. Chitnis T, Najafian N, Benou C, Salama AD, Grusby MJ, Sayegh MH, Khoury SJ. Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. J Clin Invest. 2001 Sep; 108(5):739-47. PMID: 11544280; PMCID: PMC209380.
  171. Chitnis T, Najafian N, Abdallah KA, Dong V, Yagita H, Sayegh MH, Khoury SJ. CD28-independent induction of experimental autoimmune encephalomyelitis. J Clin Invest. 2001 Mar; 107(5):575-83. PMID: 11238558; PMCID: PMC199425.
  172. Issazadeh S, Abdallah K, Chitnis T, Chandraker A, Wells AD, Turka LA, Sayegh MH, Khoury SJ. Role of passive T-cell death in chronic experimental autoimmune encephalomyelitis. J Clin Invest. 2000 Apr; 105(8):1109-16. PMID: 10772655; PMCID: PMC300830.
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