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Edwin Kepner Silverman, Ph.D., M.D.

Co-Author

This page shows the publications co-authored by Edwin Silverman and Michael Cho.
Connection Strength

6.188
  1. Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation. Respir Res. 2010 Mar 16; 11:30.
    View in: PubMed
    Score: 0.419
  2. Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet. 2010 Mar; 42(3):200-2.
    View in: PubMed
    Score: 0.418
  3. High-resolution melting curve analysis of genomic and whole-genome amplified DNA. Clin Chem. 2008 Dec; 54(12):2055-8.
    View in: PubMed
    Score: 0.384
  4. Analysis of exonic elastin variants in severe, early-onset chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2009 Jun; 40(6):751-5.
    View in: PubMed
    Score: 0.383
  5. Genome-Wide Association Analysis of Single-Breath DlCO. Am J Respir Cell Mol Biol. 2019 05; 60(5):523-531.
    View in: PubMed
    Score: 0.197
  6. Assessing pleiotropy and mediation in genetic loci associated with chronic obstructive pulmonary disease. Genet Epidemiol. 2019 04; 43(3):318-329.
    View in: PubMed
    Score: 0.194
  7. Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2018 11; 59(5):614-622.
    View in: PubMed
    Score: 0.191
  8. Whole exome sequencing analysis in severe chronic obstructive pulmonary disease. Hum Mol Genet. 2018 11 01; 27(21):3801-3812.
    View in: PubMed
    Score: 0.191
  9. Integration of Molecular Interactome and Targeted Interaction Analysis to Identify a COPD Disease Network Module. Sci Rep. 2018 09 27; 8(1):14439.
    View in: PubMed
    Score: 0.189
  10. Integrative genomics identifies new genes associated with severe COPD and emphysema. Respir Res. 2018 03 22; 19(1):46.
    View in: PubMed
    Score: 0.183
  11. Progress in disease progression genetics: dissecting the genetic origins of lung function decline in COPD. Thorax. 2017 05; 72(5):389-390.
    View in: PubMed
    Score: 0.170
  12. Gene-based segregation method for identifying rare variants in family-based sequencing studies. Genet Epidemiol. 2017 05; 41(4):309-319.
    View in: PubMed
    Score: 0.169
  13. Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1. J Cachexia Sarcopenia Muscle. 2017 Jun; 8(3):428-436.
    View in: PubMed
    Score: 0.168
  14. Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD. BMC Syst Biol. 2014 Jun 25; 8:78.
    View in: PubMed
    Score: 0.141
  15. Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema. Thorax. 2014 May; 69(5):415-22.
    View in: PubMed
    Score: 0.138
  16. Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. Lancet Respir Med. 2014 Mar; 2(3):214-25.
    View in: PubMed
    Score: 0.137
  17. Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells. Genomics. 2013 May; 101(5):263-72.
    View in: PubMed
    Score: 0.129
  18. CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland. Am J Respir Cell Mol Biol. 2012 Aug; 47(2):203-8.
    View in: PubMed
    Score: 0.121
  19. Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP. Hum Mol Genet. 2012 Mar 15; 21(6):1325-35.
    View in: PubMed
    Score: 0.118
  20. A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. Hum Mol Genet. 2012 Feb 15; 21(4):947-57.
    View in: PubMed
    Score: 0.118
  21. Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report. COPD. 2011 Apr; 8(2):121-35.
    View in: PubMed
    Score: 0.113
  22. Folliculin mutations are not associated with severe COPD. BMC Med Genet. 2008 Dec 30; 9:120.
    View in: PubMed
    Score: 0.096
  23. Exploring the cross-phenotype network region of disease modules reveals concordant and discordant pathways between chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Hum Mol Genet. 2019 07 15; 28(14):2352-2364.
    View in: PubMed
    Score: 0.050
  24. Integrative Genomics Analysis Identifies ACVR1B as a Candidate Causal Gene of Emphysema Distribution. Am J Respir Cell Mol Biol. 2019 04; 60(4):388-398.
    View in: PubMed
    Score: 0.049
  25. Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations. Nat Genet. 2019 03; 51(3):494-505.
    View in: PubMed
    Score: 0.049
  26. Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays. Am J Respir Crit Care Med. 2019 01 01; 199(1):52-61.
    View in: PubMed
    Score: 0.048
  27. Childhood asthma is associated with COPD and known asthma variants in COPDGene: a genome-wide association study. Respir Res. 2018 Oct 29; 19(1):209.
    View in: PubMed
    Score: 0.048
  28. Genomics and response to long-term oxygen therapy in chronic obstructive pulmonary disease. J Mol Med (Berl). 2018 12; 96(12):1375-1385.
    View in: PubMed
    Score: 0.048
  29. Longitudinal Modeling of Lung Function Trajectories in Smokers with and without Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 10 15; 198(8):1033-1042.
    View in: PubMed
    Score: 0.048
  30. Human Lung DNA Methylation Quantitative Trait Loci Colocalize with Chronic Obstructive Pulmonary Disease Genome-Wide Association Loci. Am J Respir Crit Care Med. 2018 05 15; 197(10):1275-1284.
    View in: PubMed
    Score: 0.046
  31. Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease. Hum Genomics. 2018 01 15; 12(1):1.
    View in: PubMed
    Score: 0.045
  32. Lobar Emphysema Distribution Is Associated With 5-Year Radiological Disease Progression. Chest. 2018 01; 153(1):65-76.
    View in: PubMed
    Score: 0.044
  33. The MUC5B promoter polymorphism is associated with specific interstitial lung abnormality subtypes. Eur Respir J. 2017 09; 50(3).
    View in: PubMed
    Score: 0.044
  34. Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects. Am J Respir Cell Mol Biol. 2017 07; 57(1):35-46.
    View in: PubMed
    Score: 0.043
  35. Do COPD subtypes really exist? COPD heterogeneity and clustering in 10 independent cohorts. Thorax. 2017 11; 72(11):998-1006.
    View in: PubMed
    Score: 0.043
  36. On the association analysis of genome-sequencing data: A spatial clustering approach for partitioning the entire genome into nonoverlapping windows. Genet Epidemiol. 2017 05; 41(4):332-340.
    View in: PubMed
    Score: 0.043
  37. Screening for interaction effects in gene expression data. PLoS One. 2017; 12(3):e0173847.
    View in: PubMed
    Score: 0.043
  38. Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution. Am J Respir Crit Care Med. 2017 03 15; 195(6):757-771.
    View in: PubMed
    Score: 0.043
  39. Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue. Sci Rep. 2017 03 13; 7:44232.
    View in: PubMed
    Score: 0.043
  40. Sex-Based Genetic Association Study Identifies CELSR1 as a Possible Chronic Obstructive Pulmonary Disease Risk Locus among Women. Am J Respir Cell Mol Biol. 2017 03; 56(3):332-341.
    View in: PubMed
    Score: 0.042
  41. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nat Genet. 2017 Mar; 49(3):426-432.
    View in: PubMed
    Score: 0.042
  42. Susceptibility to Childhood Pneumonia: A Genome-Wide Analysis. Am J Respir Cell Mol Biol. 2017 01; 56(1):20-28.
    View in: PubMed
    Score: 0.042
  43. DNA methylation profiling in human lung tissue identifies genes associated with COPD. Epigenetics. 2016 Oct 02; 11(10):730-739.
    View in: PubMed
    Score: 0.041
  44. Increasing Generality and Power of Rare-Variant Tests by Utilizing Extended Pedigrees. Am J Hum Genet. 2016 Oct 06; 99(4):846-859.
    View in: PubMed
    Score: 0.041
  45. Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med. 2016 May 12; 374(19):1842-1852.
    View in: PubMed
    Score: 0.040
  46. Association Between Interstitial Lung Abnormalities and All-Cause Mortality. JAMA. 2016 Feb 16; 315(7):672-81.
    View in: PubMed
    Score: 0.040
  47. Sex-specific features of emphysema among current and former smokers with COPD. Eur Respir J. 2016 Jan; 47(1):104-12.
    View in: PubMed
    Score: 0.039
  48. The impact of genetic variation and cigarette smoke on DNA methylation in current and former smokers from the COPDGene study. Epigenetics. 2015; 10(11):1064-73.
    View in: PubMed
    Score: 0.037
  49. Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus. BMC Pulm Med. 2014 Oct 24; 14:164.
    View in: PubMed
    Score: 0.036
  50. Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci. Hum Mol Genet. 2015 Feb 15; 24(4):1200-10.
    View in: PubMed
    Score: 0.036
  51. Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks. Hum Hered. 2014; 78(3-4):131-9.
    View in: PubMed
    Score: 0.036
  52. DNAH5 is associated with total lung capacity in chronic obstructive pulmonary disease. Respir Res. 2014 Aug 20; 15:97.
    View in: PubMed
    Score: 0.036
  53. Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene. Respir Med. 2014 Oct; 108(10):1469-80.
    View in: PubMed
    Score: 0.036
  54. Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study. Ann Am Thorac Soc. 2014 Mar; 11(3):326-34.
    View in: PubMed
    Score: 0.034
  55. On the simultaneous association analysis of large genomic regions: a massive multi-locus association test. Bioinformatics. 2014 Jan 15; 30(2):157-64.
    View in: PubMed
    Score: 0.034
  56. Heritability of chronic obstructive pulmonary disease and related phenotypes in smokers. Am J Respir Crit Care Med. 2013 Oct 15; 188(8):941-7.
    View in: PubMed
    Score: 0.034
  57. Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility. Hum Genet. 2013 Apr; 132(4):431-41.
    View in: PubMed
    Score: 0.032
  58. Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2012 Dec 15; 186(12):1238-47.
    View in: PubMed
    Score: 0.032
  59. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. Am J Respir Crit Care Med. 2012 Oct 01; 186(7):622-32.
    View in: PubMed
    Score: 0.031
  60. Genetic association between human chitinases and lung function in COPD. Hum Genet. 2012 Jul; 131(7):1105-14.
    View in: PubMed
    Score: 0.030
  61. Genetics of sputum gene expression in chronic obstructive pulmonary disease. PLoS One. 2011; 6(9):e24395.
    View in: PubMed
    Score: 0.029
  62. Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax. 2011 Dec; 66(12):1085-90.
    View in: PubMed
    Score: 0.029
  63. Genome-wide association study of smoking behaviours in patients with COPD. Thorax. 2011 Oct; 66(10):894-902.
    View in: PubMed
    Score: 0.029
  64. The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility. Am J Respir Cell Mol Biol. 2011 Dec; 45(6):1147-53.
    View in: PubMed
    Score: 0.029
  65. On the follow-up of genome-wide association studies: an overall test for the most promising SNPs. Genet Epidemiol. 2011 Jul; 35(5):303-9.
    View in: PubMed
    Score: 0.028
  66. Genome-wide association analysis of body mass in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2011 Aug; 45(2):304-10.
    View in: PubMed
    Score: 0.027
  67. Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. Am J Respir Crit Care Med. 2011 Jan 01; 183(1):43-9.
    View in: PubMed
    Score: 0.027
  68. Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010 Dec 15; 182(12):1498-505.
    View in: PubMed
    Score: 0.027
  69. MMP12, lung function, and COPD in high-risk populations. N Engl J Med. 2009 Dec 31; 361(27):2599-608.
    View in: PubMed
    Score: 0.026
  70. The COPD genetic association compendium: a comprehensive online database of COPD genetic associations. Hum Mol Genet. 2010 Feb 01; 19(3):526-34.
    View in: PubMed
    Score: 0.026
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.