Harvard Catalyst Profiles

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Mehmet Toner, Ph.D.

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Mentoring

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01CA214297 (TONER, MEHMET) May 8, 2018 - Apr 30, 2023
    NIH/NCI
    Metastasis and biophysics of clusters of circulating tumor cells in the microcirculation
    Role: Principal Investigator
  2. R01DK114506 (TONER, MEHMET) Jul 17, 2017 - Mar 31, 2021
    NIH/NIDDK
    High subzero preservation of liver for transplantation
    Role: Principal Investigator
  3. R01EB023812 (YARMUSH, MARTIN L) Sep 30, 2016 - Jul 31, 2020
    NIH/NIBIB
    Real Time Elucidation of Drug-Drug Interactions via Dual Reporter Cell Technology and Microfabricated Arrays
    Role: Principal Investigator
  4. U01EB012493 (TONER, MEHMET) Sep 30, 2010 - Jun 30, 2019
    NIH/NIBIB
    Point-of care Microfluidics for Early Detection of Cancer
    Role: Co-Principal Investigator
  5. R21HD061297 (TONER, MEHMET) Sep 30, 2009 - Aug 31, 2012
    NIH/NICHD
    Novel Microcapillary Technology for the Cryopreservation of Human Oocytes
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Weng L, Tessier SN, Smith K, Edd JF, Stott SL, Toner M. Bacterial Ice Nucleation in Monodisperse D2O and H2O-in-Oil Emulsions. Langmuir. 2016 09 13; 32(36):9229-36. PMID: 27495973.
    Citations: 2     Fields:    Translation:Cells
  2. Liu J, Tanrikut C, Wright DL, Lee GY, Toner M, Biggers JD, Toth TL. Cryopreservation of human spermatozoa with minimal non-permeable cryoprotectant. Cryobiology. 2016 10; 73(2):162-7. PMID: 27498216.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  3. Blumrosen G, Abazari A, Golberg A, Yarmush ML, Toner M. Single-step electrical field strength screening to determine electroporation induced transmembrane transport parameters. Biochim Biophys Acta. 2016 09; 1858(9):2041-2049. PMID: 27263825.
    Citations: 1     Fields:    Translation:HumansCells
  4. Au SH, Storey BD, Moore JC, Tang Q, Chen YL, Javaid S, Sarioglu AF, Sullivan R, Madden MW, O'Keefe R, Haber DA, Maheswaran S, Langenau DM, Stott SL, Toner M. Clusters of circulating tumor cells traverse capillary-sized vessels. Proc Natl Acad Sci U S A. 2016 May 03; 113(18):4947-52. PMID: 27091969; PMCID: PMC4983862.
    Citations: 27     Fields:    Translation:HumansCells
  5. Shaw Bagnall J, Byun S, Miyamoto DT, Kang JH, Maheswaran S, Stott SL, Toner M, Manalis SR. Deformability-based cell selection with downstream immunofluorescence analysis. Integr Biol (Camb). 2016 05 16; 8(5):654-64. PMID: 26999591; PMCID: PMC4868639.
    Citations: 2     Fields:    Translation:Cells
  6. Chen L, An HZ, Haghgooie R, Shank AT, Martel JM, Toner M, Doyle PS. Flexible Octopus-Shaped Hydrogel Particles for Specific Cell Capture. Small. 2016 Apr; 12(15):2001-2008. PMID: 26929053.
    Citations: 3     Fields:    Translation:HumansCells
  7. Wong KH, Sandlin RD, Carey TR, Miller KL, Shank AT, Oklu R, Maheswaran S, Haber DA, Irimia D, Stott SL, Toner M. The Role of Physical Stabilization in Whole Blood Preservation. Sci Rep. 2016 Feb 15; 6:21023. PMID: 26876805; PMCID: PMC4753451.
    Citations: 4     Fields:    Translation:HumansCells
  8. Shaw Bagnall J, Byun S, Begum S, Miyamoto DT, Hecht VC, Maheswaran S, Stott SL, Toner M, Hynes RO, Manalis SR. Deformability of Tumor Cells versus Blood Cells. Sci Rep. 2015 Dec 18; 5:18542. PMID: 26679988.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  9. Sundaresan TK, Sequist LV, Heymach JV, Riely GJ, Jänne PA, Koch WH, Sullivan JP, Fox DB, Maher R, Muzikansky A, Webb A, Tran HT, Giri U, Fleisher M, Yu HA, Wei W, Johnson BE, Barber TA, Walsh JR, Engelman JA, Stott SL, Kapur R, Maheswaran S, Toner M, Haber DA. Detection of T790M, the Acquired Resistance EGFR Mutation, by Tumor Biopsy versus Noninvasive Blood-Based Analyses. Clin Cancer Res. 2016 Mar 01; 22(5):1103-10. PMID: 26446944.
    Citations: 73     Fields:    Translation:HumansCellsCTClinical Trials
  10. Miyamoto DT, Zheng Y, Wittner BS, Lee RJ, Zhu H, Broderick KT, Desai R, Fox DB, Brannigan BW, Trautwein J, Arora KS, Desai N, Dahl DM, Sequist LV, Smith MR, Kapur R, Wu CL, Shioda T, Ramaswamy S, Ting DT, Toner M, Maheswaran S, Haber DA. RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance. Science. 2015 Sep 18; 349(6254):1351-6. PMID: 26383955; PMCID: PMC4872391.
    Citations: 97     Fields:    Translation:HumansAnimalsCells
  11. Abazari A, Meimetis LG, Budin G, Bale SS, Weissleder R, Toner M. Engineered Trehalose Permeable to Mammalian Cells. PLoS One. 2015; 10(6):e0130323. PMID: 26115179; PMCID: PMC4482662.
    Citations: 7     Fields:    Translation:AnimalsCells
  12. Li W, Reátegui E, Park MH, Castleberry S, Deng JZ, Hsu B, Mayner S, Jensen AE, Sequist LV, Maheswaran S, Haber DA, Toner M, Stott SL, Hammond PT. Biodegradable nano-films for capture and non-invasive release of circulating tumor cells. Biomaterials. 2015 Oct; 65:93-102. PMID: 26142780.
    Citations: 7     Fields:    Translation:HumansCells
  13. Kojic N, Miloševic M, Petrovic D, Isailovic V, Sarioglu AF, Haber DA, Kojic M, Toner M. A computational study of circulating large tumor cells traversing microvessels. Comput Biol Med. 2015 Aug; 63:187-95. PMID: 26093786; PMCID: PMC4819961.
    Citations: 2     Fields:    Translation:HumansCells
  14. Martel JM, Smith KC, Dlamini M, Pletcher K, Yang J, Karabacak M, Haber DA, Kapur R, Toner M. Continuous Flow Microfluidic Bioparticle Concentrator. Sci Rep. 2015 Jun 10; 5:11300. PMID: 26061253; PMCID: PMC4462155.
    Citations: 11     Fields:    
  15. Sarioglu AF, Aceto N, Kojic N, Donaldson MC, Zeinali M, Hamza B, Engstrom A, Zhu H, Sundaresan TK, Miyamoto DT, Luo X, Bardia A, Wittner BS, Ramaswamy S, Shioda T, Ting DT, Stott SL, Kapur R, Maheswaran S, Haber DA, Toner M. A microfluidic device for label-free, physical capture of circulating tumor cell clusters. Nat Methods. 2015 Jul; 12(7):685-91. PMID: 25984697; PMCID: PMC4490017.
    Citations: 72     Fields:    Translation:HumansCells
  16. Javaid S, Zhang J, Smolen GA, Yu M, Wittner BS, Singh A, Arora KS, Madden MW, Desai R, Zubrowski MJ, Schott BJ, Ting DT, Stott SL, Toner M, Maheswaran S, Shioda T, Ramaswamy S, Haber DA. MAPK7 Regulates EMT Features and Modulates the Generation of CTCs. Mol Cancer Res. 2015 May; 13(5):934-43. PMID: 25678598; PMCID: PMC4433453.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  17. Reátegui E, Aceto N, Lim EJ, Sullivan JP, Jensen AE, Zeinali M, Martel JM, Aranyosi AJ, Li W, Castleberry S, Bardia A, Sequist LV, Haber DA, Maheswaran S, Hammond PT, Toner M, Stott SL. Tunable nanostructured coating for the capture and selective release of viable circulating tumor cells. Adv Mater. 2015 Mar 04; 27(9):1593-9. PMID: 25640006; PMCID: PMC4492283.
    Citations: 19     Fields:    Translation:HumansCells
  18. Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B. Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays. Nat Commun. 2014 Dec 09; 5:5662. PMID: 25489927; PMCID: PMC4261930.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  19. Abazari A, Chakraborty N, Hand S, Aksan A, Toner M. A Raman microspectroscopy study of water and trehalose in spin-dried cells. Biophys J. 2014 Nov 18; 107(10):2253-62. PMID: 25418294; PMCID: PMC4241435.
    Citations: 1     Fields:    Translation:HumansCells
  20. Bersani F, Lee J, Yu M, Morris R, Desai R, Ramaswamy S, Toner M, Haber DA, Parekkadan B. Bioengineered implantable scaffolds as a tool to study stromal-derived factors in metastatic cancer models. Cancer Res. 2014 Dec 15; 74(24):7229-38. PMID: 25339351; PMCID: PMC4267901.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  21. Ting DT, Wittner BS, Ligorio M, Vincent Jordan N, Shah AM, Miyamoto DT, Aceto N, Bersani F, Brannigan BW, Xega K, Ciciliano JC, Zhu H, MacKenzie OC, Trautwein J, Arora KS, Shahid M, Ellis HL, Qu N, Bardeesy N, Rivera MN, Deshpande V, Ferrone CR, Kapur R, Ramaswamy S, Shioda T, Toner M, Maheswaran S, Haber DA. Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells. Cell Rep. 2014 Sep 25; 8(6):1905-1918. PMID: 25242334; PMCID: PMC4230325.
    Citations: 87     Fields:    Translation:HumansAnimalsCells
  22. Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, Maheswaran S. Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis. Cell. 2014 Aug 28; 158(5):1110-1122. PMID: 25171411; PMCID: PMC4149753.
    Citations: 292     Fields:    Translation:HumansAnimalsCells
  23. Sullivan JP, Nahed BV, Madden MW, Oliveira SM, Springer S, Bhere D, Chi AS, Wakimoto H, Rothenberg SM, Sequist LV, Kapur R, Shah K, Iafrate AJ, Curry WT, Loeffler JS, Batchelor TT, Louis DN, Toner M, Maheswaran S, Haber DA. Brain tumor cells in circulation are enriched for mesenchymal gene expression. Cancer Discov. 2014 Nov; 4(11):1299-309. PMID: 25139148; PMCID: PMC4221467.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  24. Wong IY, Javaid S, Wong EA, Perk S, Haber DA, Toner M, Irimia D. Collective and individual migration following the epithelial-mesenchymal transition. Nat Mater. 2014 Nov; 13(11):1063-71. PMID: 25129619; PMCID: PMC4209198.
    Citations: 20     Fields:    Translation:HumansCells
  25. Nahed BV, Sullivan JP, Madden MW, Oliveira SM, Chi AS, Springer S, Wakimoto H, Bhere D, Shah A, Spuhler P, Batchelor T, Louis DN, Toner M, Maheswaran S, Haber DA. American brain tumor association young investigator award 198 circulating tumor cells in patients with glioblastoma. Neurosurgery. 2014 Aug; 61 Suppl 1:226. PMID: 25032649.
    Citations:    
  26. Yu M, Bardia A, Aceto N, Bersani F, Madden MW, Donaldson MC, Desai R, Zhu H, Comaills V, Zheng Z, Wittner BS, Stojanov P, Brachtel E, Sgroi D, Kapur R, Shioda T, Ting DT, Ramaswamy S, Getz G, Iafrate AJ, Benes C, Toner M, Maheswaran S, Haber DA. Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility. Science. 2014 Jul 11; 345(6193):216-20. PMID: 25013076; PMCID: PMC4358808.
    Citations: 164     Fields:    Translation:HumansAnimalsCells
  27. Berendsen TA, Bruinsma BG, Puts CF, Saeidi N, Usta OB, Uygun BE, Izamis ML, Toner M, Yarmush ML, Uygun K. Supercooling enables long-term transplantation survival following 4 days of liver preservation. Nat Med. 2014 Jul; 20(7):790-3. PMID: 24973919; PMCID: PMC4141719.
    Citations: 16     Fields:    Translation:Animals
  28. Lim EJ, Ober TJ, Edd JF, Desai SP, Neal D, Bong KW, Doyle PS, McKinley GH, Toner M. Inertio-elastic focusing of bioparticles in microchannels at high throughput. Nat Commun. 2014 Jun 18; 5:4120. PMID: 24939508; PMCID: PMC4476514.
    Citations: 12     Fields:    Translation:Cells
  29. Liu J, Lee GY, Lawitts JA, Toner M, Biggers JD. Live pups from evaporatively dried mouse sperm stored at ambient temperature for up to 2 years. PLoS One. 2014; 9(6):e99809. PMID: 24924588; PMCID: PMC4055687.
    Citations: 4     Fields:    Translation:AnimalsCells
  30. Martel JM, Toner M. Inertial focusing in microfluidics. Annu Rev Biomed Eng. 2014 Jul 11; 16:371-96. PMID: 24905880; PMCID: PMC4467210.
    Citations: 35     Fields:    Translation:HumansAnimals
  31. Luo X, Mitra D, Sullivan RJ, Wittner BS, Kimura AM, Pan S, Hoang MP, Brannigan BW, Lawrence DP, Flaherty KT, Sequist LV, McMahon M, Bosenberg MW, Stott SL, Ting DT, Ramaswamy S, Toner M, Fisher DE, Maheswaran S, Haber DA. Isolation and molecular characterization of circulating melanoma cells. Cell Rep. 2014 May 08; 7(3):645-53. PMID: 24746818; PMCID: PMC4079008.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  32. Karabacak NM, Spuhler PS, Fachin F, Lim EJ, Pai V, Ozkumur E, Martel JM, Kojic N, Smith K, Chen PI, Yang J, Hwang H, Morgan B, Trautwein J, Barber TA, Stott SL, Maheswaran S, Kapur R, Haber DA, Toner M. Microfluidic, marker-free isolation of circulating tumor cells from blood samples. Nat Protoc. 2014 Mar; 9(3):694-710. PMID: 24577360; PMCID: PMC4179254.
    Citations: 97     Fields:    Translation:HumansCells
  33. Wong IY, Bhatia SN, Toner M. Nanotechnology: emerging tools for biology and medicine. Genes Dev. 2013 Nov 15; 27(22):2397-408. PMID: 24240230; PMCID: PMC3841729.
    Citations: 9     Fields:    Translation:Humans
  34. Mittal S, Wong IY, Yanik AA, Deen WM, Toner M. Discontinuous nanoporous membranes reduce non-specific fouling for immunoaffinity cell capture. Small. 2013 Dec 20; 9(24):4207-14. PMID: 23766297.
    Citations: 2     Fields:    Translation:HumansCells
  35. Mantel PY, Hoang AN, Goldowitz I, Potashnikova D, Hamza B, Vorobjev I, Ghiran I, Toner M, Irimia D, Ivanov AR, Barteneva N, Marti M. Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe. 2013 May 15; 13(5):521-534. PMID: 23684304.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  36. Desai SP, Bhatia SN, Toner M, Irimia D. Mitochondrial localization and the persistent migration of epithelial cancer cells. Biophys J. 2013 May 07; 104(9):2077-88. PMID: 23663851; PMCID: PMC3647149.
    Citations: 53     Fields:    Translation:HumansCells
  37. Ozkumur E, Shah AM, Ciciliano JC, Emmink BL, Miyamoto DT, Brachtel E, Yu M, Chen PI, Morgan B, Trautwein J, Kimura A, Sengupta S, Stott SL, Karabacak NM, Barber TA, Walsh JR, Smith K, Spuhler PS, Sullivan JP, Lee RJ, Ting DT, Luo X, Shaw AT, Bardia A, Sequist LV, Louis DN, Maheswaran S, Kapur R, Haber DA, Toner M. Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells. Sci Transl Med. 2013 Apr 03; 5(179):179ra47. PMID: 23552373; PMCID: PMC3760275.
    Citations: 220     Fields:    Translation:HumansCells
  38. Yu M, Bardia A, Wittner BS, Stott SL, Smas ME, Ting DT, Isakoff SJ, Ciciliano JC, Wells MN, Shah AM, Concannon KF, Donaldson MC, Sequist LV, Brachtel E, Sgroi D, Baselga J, Ramaswamy S, Toner M, Haber DA, Maheswaran S. Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science. 2013 Feb 01; 339(6119):580-4. PMID: 23372014.
    Citations: 541     Fields:    Translation:HumansAnimalsCells
  39. Liong M, Hoang AN, Chung J, Gural N, Ford CB, Min C, Shah RR, Ahmad R, Fernandez-Suarez M, Fortune SM, Toner M, Lee H, Weissleder R. Magnetic barcode assay for genetic detection of pathogens. Nat Commun. 2013; 4:1752. PMID: 23612293.
    Citations: 15     Fields:    Translation:HumansCells
  40. Kotz KT, Petrofsky AC, Haghgooie R, Granier R, Toner M, Tompkins RG. Inertial focusing cytometer with integrated optics for particle characterization. Technology (Singap World Sci). 2013; 1(1):27-36. PMID: 25346940.
    Citations: 3     
  41. Li S, Chakraborty N, Borcar A, Menze MA, Toner M, Hand SC. Late embryogenesis abundant proteins protect human hepatoma cells during acute desiccation. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):20859-64. PMID: 23185012; PMCID: PMC3529014.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  42. Borcar A, Menze MA, Toner M, Hand SC. Metabolic preconditioning of mammalian cells: mimetic agents for hypoxia lack fidelity in promoting phosphorylation of pyruvate dehydrogenase. Cell Tissue Res. 2013 Jan; 351(1):99-106. PMID: 23138570; PMCID: PMC3537919.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  43. Miyamoto DT, Lee RJ, Stott SL, Ting DT, Wittner BS, Ulman M, Smas ME, Lord JB, Brannigan BW, Trautwein J, Bander NH, Wu CL, Sequist LV, Smith MR, Ramaswamy S, Toner M, Maheswaran S, Haber DA. Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer. Cancer Discov. 2012 Nov; 2(11):995-1003. PMID: 23093251; PMCID: PMC3508523.
    Citations: 80     Fields:    Translation:HumansCells
  44. El-Haibi CP, Bell GW, Zhang J, Collmann AY, Wood D, Scherber CM, Csizmadia E, Mariani O, Zhu C, Campagne A, Toner M, Bhatia SN, Irimia D, Vincent-Salomon A, Karnoub AE. Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17460-5. PMID: 23033492; PMCID: PMC3491529.
    Citations: 50     Fields:    Translation:HumansCells
  45. Lechene CP, Lee GY, Poczatek JC, Toner M, Biggers JD. 3D multi-isotope imaging mass spectrometry reveals penetration of 18O-trehalose in mouse sperm nucleus. PLoS One. 2012; 7(8):e42267. PMID: 22952592; PMCID: PMC3428319.
    Citations: 6     Fields:    Translation:AnimalsCells
  46. Yu M, Ting DT, Stott SL, Wittner BS, Ozsolak F, Paul S, Ciciliano JC, Smas ME, Winokur D, Gilman AJ, Ulman MJ, Xega K, Contino G, Alagesan B, Brannigan BW, Milos PM, Ryan DP, Sequist LV, Bardeesy N, Ramaswamy S, Toner M, Maheswaran S, Haber DA. RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis. Nature. 2012 Jul 26; 487(7408):510-3. PMID: 22763454; PMCID: PMC3408856.
    Citations: 160     Fields:    Translation:HumansAnimalsCells
  47. Chen GD, Fachin F, Colombini E, Wardle BL, Toner M. Nanoporous micro-element arrays for particle interception in microfluidic cell separation. Lab Chip. 2012 Sep 07; 12(17):3159-67. PMID: 22763858; PMCID: PMC4005922.
    Citations: 2     Fields:    Translation:HumansCells
  48. Shah AM, Yu M, Nakamura Z, Ciciliano J, Ulman M, Kotz K, Stott SL, Maheswaran S, Haber DA, Toner M. Biopolymer system for cell recovery from microfluidic cell capture devices. Anal Chem. 2012 Apr 17; 84(8):3682-8. PMID: 22414137; PMCID: PMC3328665.
    Citations: 22     Fields:    Translation:HumansCells
  49. Martel JM, Toner M. Inertial focusing dynamics in spiral microchannels. Phys Fluids (1994). 2012 Mar; 24(3):32001. PMID: 22454556.
    Citations: 22     
  50. Lim EJ, Ober TJ, Edd JF, McKinley GH, Toner M. Visualization of microscale particle focusing in diluted and whole blood using particle trajectory analysis. Lab Chip. 2012 Jun 21; 12(12):2199-210. PMID: 22382737; PMCID: PMC4211080.
    Citations: 10     Fields:    Translation:HumansCells
  51. Mittal S, Wong IY, Deen WM, Toner M. Antibody-functionalized fluid-permeable surfaces for rolling cell capture at high flow rates. Biophys J. 2012 Feb 22; 102(4):721-30. PMID: 22385842; PMCID: PMC3283808.
    Citations: 8     Fields:    Translation:HumansCells
  52. Scherber C, Aranyosi AJ, Kulemann B, Thayer SP, Toner M, Iliopoulos O, Irimia D. Epithelial cell guidance by self-generated EGF gradients. Integr Biol (Camb). 2012 Mar; 4(3):259-69. PMID: 22314635; PMCID: PMC3440622.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  53. Li MW, Baridon B, Trainor A, Djan E, Koehne A, Griffey SM, Biggers JD, Toner M, Lloyd KC. Mutant mice derived by ICSI of evaporatively dried spermatozoa exhibit expected phenotype. Reproduction. 2012 Apr; 143(4):449-53. PMID: 22274886.
    Citations: 1     Fields:    Translation:AnimalsCells
  54. Liu J, Lee GY, Lawitts JA, Toner M, Biggers JD. Preservation of mouse sperm by convective drying and storing in 3-O-methyl-D-glucose. PLoS One. 2012; 7(1):e29924. PMID: 22272261; PMCID: PMC3260178.
    Citations: 7     Fields:    Translation:AnimalsCells
  55. Hipp J, Monaco J, Kunju LP, Cheng J, Yagi Y, Rodriguez-Canales J, Emmert-Buck MR, Hewitt S, Feldman MD, Tomaszewski JE, Toner M, Tompkins RG, Flotte T, Lucas D, Gilbertson JR, Madabhushi A, Balis U. Integration of architectural and cytologic driven image algorithms for prostate adenocarcinoma identification. Anal Cell Pathol (Amst). 2012; 35(4):251-65. PMID: 22425661; PMCID: PMC4605585.
    Citations: 2     Fields:    Translation:Humans
  56. Aldridge BB, Fernandez-Suarez M, Heller D, Ambravaneswaran V, Irimia D, Toner M, Fortune SM. Asymmetry and aging of mycobacterial cells lead to variable growth and antibiotic susceptibility. Science. 2012 Jan 06; 335(6064):100-4. PMID: 22174129; PMCID: PMC3397429.
    Citations: 97     Fields:    Translation:Cells
  57. Chakraborty N, Menze MA, Elmoazzen H, Vu H, Yarmush ML, Hand SC, Toner M. Trehalose transporter from African chironomid larvae improves desiccation tolerance of Chinese hamster ovary cells. Cryobiology. 2012 Apr; 64(2):91-6. PMID: 22155480.
    Citations: 6     Fields:    Translation:AnimalsCells
  58. Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R. Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance. Bioconjug Chem. 2011 Dec 21; 22(12):2390-4. PMID: 22043803; PMCID: PMC3263317.
    Citations: 12     Fields:    Translation:HumansCells
  59. Watkins N, Irimia D, Toner M, Bashir R. On a chip. IEEE Pulse. 2011 Nov; 2(6):19-27. PMID: 22147065; PMCID: PMC4493052.
    Citations: 1     Fields:    Translation:HumansCells
  60. Chakraborty N, Menze MA, Malsam J, Aksan A, Hand SC, Toner M. Cryopreservation of spin-dried mammalian cells. PLoS One. 2011; 6(9):e24916. PMID: 21966385; PMCID: PMC3178566.
    Citations: 3     Fields:    Translation:AnimalsCells
  61. Warner EA, Kotz KT, Ungaro RF, Abouhamze AS, Lopez MC, Cuenca AG, Kelly-Scumpia KM, Moreno C, O'Malley KA, Lanz JD, Baker HV, Martin LC, Toner M, Tompkins RG, Efron PA, Moldawer LL. Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage. Lab Invest. 2011 Dec; 91(12):1787-95. PMID: 21931299; PMCID: PMC3957199.
    Citations: 12     Fields:    Translation:HumansCells
  62. Heo YS, Lee HJ, Hassell BA, Irimia D, Toth TL, Elmoazzen H, Toner M. Controlled loading of cryoprotectants (CPAs) to oocyte with linear and complex CPA profiles on a microfluidic platform. Lab Chip. 2011 Oct 21; 11(20):3530-7. PMID: 21887438; PMCID: PMC3755277.
    Citations: 13     Fields:    Translation:AnimalsCells
  63. Hipp J, Flotte T, Monaco J, Cheng J, Madabhushi A, Yagi Y, Rodriguez-Canales J, Emmert-Buck M, Dugan MC, Hewitt S, Toner M, Tompkins RG, Lucas D, Gilbertson JR, Balis UJ. Computer aided diagnostic tools aim to empower rather than replace pathologists: Lessons learned from computational chess. J Pathol Inform. 2011; 2:25. PMID: 21773056.
    Citations: 7     
  64. Kenar H, Kose GT, Toner M, Kaplan DL, Hasirci V. A 3D aligned microfibrous myocardial tissue construct cultured under transient perfusion. Biomaterials. 2011 Aug; 32(23):5320-9. PMID: 21570112.
    Citations: 9     Fields:    Translation:HumansCells
  65. Chen GD, Fachin F, Fernandez-Suarez M, Wardle BL, Toner M. Nanoporous elements in microfluidics for multiscale manipulation of bioparticles. Small. 2011 Apr 18; 7(8):1061-7. PMID: 21413145; PMCID: PMC3141316.
    Citations: 13     Fields:    
  66. Hipp JD, Cheng JY, Toner M, Tompkins RG, Balis UJ. Spatially Invariant Vector Quantization: A pattern matching algorithm for multiple classes of image subject matter including pathology. J Pathol Inform. 2011 Feb 26; 2:13. PMID: 21383936; PMCID: PMC3049270.
    Citations: 7     
  67. Hand SC, Menze MA, Borcar A, Patil Y, Covi JA, Reynolds JA, Toner M. Metabolic restructuring during energy-limited states: insights from Artemia franciscana embryos and other animals. J Insect Physiol. 2011 May; 57(5):584-94. PMID: 21335009; PMCID: PMC3104064.
    Citations: 20     Fields:    Translation:AnimalsCells
  68. Yu M, Stott S, Toner M, Maheswaran S, Haber DA. Circulating tumor cells: approaches to isolation and characterization. J Cell Biol. 2011 Feb 07; 192(3):373-82. PMID: 21300848; PMCID: PMC3101098.
    Citations: 289     Fields:    Translation:HumansAnimalsCells
  69. Chakraborty N, Chang A, Elmoazzen H, Menze MA, Hand SC, Toner M. A spin-drying technique for lyopreservation of mammalian cells. Ann Biomed Eng. 2011 May; 39(5):1582-91. PMID: 21293974.
    Citations: 10     Fields:    Translation:AnimalsCells
  70. Watkins NN, Sridhar S, Cheng X, Chen GD, Toner M, Rodriguez W, Bashir R. A microfabricated electrical differential counter for the selective enumeration of CD4+ T lymphocytes. Lab Chip. 2011 Apr 21; 11(8):1437-47. PMID: 21283908; PMCID: PMC3141315.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  71. Hand SC, Menze MA, Toner M, Boswell L, Moore D. LEA proteins during water stress: not just for plants anymore. Annu Rev Physiol. 2011; 73:115-34. PMID: 21034219.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  72. Kane BJ, Younan G, Helm D, Dastouri P, Prentice-Mott H, Irimia D, Chan RK, Toner M, Orgill DP. Controlled induction of distributed microdeformation in wounded tissue via a microchamber array dressing. J Biomed Mater Res A. 2010 Nov; 95(2):333-40. PMID: 20607869; PMCID: PMC2943997.
    Citations:    Fields:    Translation:Animals
  73. Prentice-Mott H, Toner M, Irimia D. Microfluidic proportional flow controller. J Micromech Microeng. 2010 Oct 15; 20(11):1-8. PMID: 21874096.
    Citations: 1     
  74. Stott SL, Hsu CH, Tsukrov DI, Yu M, Miyamoto DT, Waltman BA, Rothenberg SM, Shah AM, Smas ME, Korir GK, Floyd FP, Gilman AJ, Lord JB, Winokur D, Springer S, Irimia D, Nagrath S, Sequist LV, Lee RJ, Isselbacher KJ, Maheswaran S, Haber DA, Toner M. Isolation of circulating tumor cells using a microvortex-generating herringbone-chip. Proc Natl Acad Sci U S A. 2010 Oct 26; 107(43):18392-7. PMID: 20930119; PMCID: PMC2972993.
    Citations: 346     Fields:    Translation:HumansCells
  75. Kotz KT, Xiao W, Miller-Graziano C, Qian WJ, Russom A, Warner EA, Moldawer LL, De A, Bankey PE, Petritis BO, Camp DG, Rosenbach AE, Goverman J, Fagan SP, Brownstein BH, Irimia D, Xu W, Wilhelmy J, Mindrinos MN, Smith RD, Davis RW, Tompkins RG, Toner M. Clinical microfluidics for neutrophil genomics and proteomics. Nat Med. 2010 Sep; 16(9):1042-7. PMID: 20802500; PMCID: PMC3136804.
    Citations: 67     Fields:    Translation:HumansCells
  76. Ambravaneswaran V, Wong IY, Aranyosi AJ, Toner M, Irimia D. Directional decisions during neutrophil chemotaxis inside bifurcating channels. Integr Biol (Camb). 2010 Nov; 2(11-12):639-47. PMID: 20676444; PMCID: PMC3001269.
    Citations: 26     Fields:    Translation:HumansCells
  77. Butler KL, Ambravaneswaran V, Agrawal N, Bilodeau M, Toner M, Tompkins RG, Fagan S, Irimia D. Burn injury reduces neutrophil directional migration speed in microfluidic devices. PLoS One. 2010 Jul 30; 5(7):e11921. PMID: 20689600; PMCID: PMC2912851.
    Citations: 43     Fields:    Translation:HumansCells
  78. Menze MA, Chakraborty N, Clavenna M, Banerjee M, Liu XH, Toner M, Hand SC. Metabolic preconditioning of cells with AICAR-riboside: improved cryopreservation and cell-type specific impacts on energetics and proliferation. Cryobiology. 2010 Aug; 61(1):79-88. PMID: 20510224; PMCID: PMC2920351.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  79. Zhou B, Xu W, Herndon D, Tompkins R, Davis R, Xiao W, Wong WH, Toner M, Warren HS, Schoenfeld DA, Rahme L, McDonald-Smith GP, Hayden D, Mason P, Fagan S, Yu YM, Cobb JP, Remick DG, Mannick JA, Lederer JA, Gamelli RL, Silver GM, West MA, Shapiro MB, Smith R, Camp DG, Qian W, Storey J, Mindrinos M, Tibshirani R, Lowry S, Calvano S, Chaudry I, West MA, Cohen M, Moore EE, Johnson J, Moldawer LL, Baker HV, Efron PA, Balis UG, Billiar TR, Ochoa JB, Sperry JL, Miller-Graziano CL, De AK, Bankey PE, Finnerty CC, Jeschke MG, Minei JP, Arnoldo BD, Hunt JL, Horton J, Cobb JP, Brownstein B, Freeman B, Maier RV, Nathens AB, Cuschieri J, Gibran N, Klein M, O'Keefe G. Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):9923-8. PMID: 20479259; PMCID: PMC2890487.
    Citations: 27     Fields:    Translation:Humans
  80. Oakey J, Applegate RW, Arellano E, Di Carlo D, Graves SW, Toner M. Particle focusing in staged inertial microfluidic devices for flow cytometry. Anal Chem. 2010 May 01; 82(9):3862-7. PMID: 20373755; PMCID: PMC3136802.
    Citations: 38     Fields:    
  81. Stott SL, Lee RJ, Nagrath S, Yu M, Miyamoto DT, Ulkus L, Inserra EJ, Ulman M, Springer S, Nakamura Z, Moore AL, Tsukrov DI, Kempner ME, Dahl DM, Wu CL, Iafrate AJ, Smith MR, Tompkins RG, Sequist LV, Toner M, Haber DA, Maheswaran S. Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer. Sci Transl Med. 2010 Mar 31; 2(25):25ra23. PMID: 20424012; PMCID: PMC3141292.
    Citations: 162     Fields:    Translation:HumansCells
  82. Sitaula R, Fowler A, Toner M, Bhowmick S. A study of the effect of sorbitol on osmotic tolerance during partial desiccation of bovine sperm. Cryobiology. 2010 Jun; 60(3):331-6. PMID: 20233588.
    Citations: 2     Fields:    Translation:AnimalsCells
  83. Bajpayee A, Edd JF, Chang A, Toner M. Concentration of glycerol in aqueous microdroplets by selective removal of water. Anal Chem. 2010 Feb 15; 82(4):1288-91. PMID: 20102162; PMCID: PMC3130205.
    Citations: 1     Fields:    
  84. Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, Brugge JS, Ramaswamy S. MYC regulation of a "poor-prognosis" metastatic cancer cell state. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3698-703. PMID: 20133671; PMCID: PMC2840447.
    Citations: 72     Fields:    Translation:Humans
  85. Chen GD, Alberts CJ, Rodriguez W, Toner M. Concentration and purification of human immunodeficiency virus type 1 virions by microfluidic separation of superparamagnetic nanoparticles. Anal Chem. 2010 Jan 15; 82(2):723-8. PMID: 19954210; PMCID: PMC2818585.
    Citations: 18     Fields:    Translation:HumansCells
  86. Cho CH, Park J, Tilles AW, Berthiaume F, Toner M, Yarmush ML. Layered patterning of hepatocytes in co-culture systems using microfabricated stencils. Biotechniques. 2010 Jan; 48(1):47-52. PMID: 20078427; PMCID: PMC3147300.
    Citations: 12     Fields:    Translation:AnimalsCells
  87. Chen C, Skog J, Hsu CH, Lessard RT, Balaj L, Wurdinger T, Carter BS, Breakefield XO, Toner M, Irimia D. Microfluidic isolation and transcriptome analysis of serum microvesicles. Lab Chip. 2010 Feb 21; 10(4):505-11. PMID: 20126692; PMCID: PMC3136803.
    Citations: 81     Fields:    Translation:HumansCells
  88. Lee HJ, Elmoazzen H, Wright D, Biggers J, Rueda BR, Heo YS, Toner M, Toth TL. Ultra-rapid vitrification of mouse oocytes in low cryoprotectant concentrations. Reprod Biomed Online. 2010 Feb; 20(2):201-8. PMID: 20113958; PMCID: PMC2818866.
    Citations: 10     Fields:    Translation:AnimalsCells
  89. Roach KL, King KR, Uygun BE, Kohane IS, Yarmush ML, Toner M. High throughput single cell bioinformatics. Biotechnol Prog. 2009 Nov-Dec; 25(6):1772-9. PMID: 19830811; PMCID: PMC3208255.
    Citations: 9     Fields:    Translation:AnimalsCells
  90. Watkins N, Venkatesan BM, Toner M, Rodriguez W, Bashir R. A robust electrical microcytometer with 3-dimensional hydrofocusing. Lab Chip. 2009 Nov 21; 9(22):3177-84. PMID: 19865723; PMCID: PMC4142320.
    Citations: 14     Fields:    Translation:HumansCells
  91. Haghgooie R, Toner M, Doyle PS. Squishy non-spherical hydrogel microparticles. Macromol Rapid Commun. 2010 Jan 18; 31(2):128-34. PMID: 21590884; PMCID: PMC3136805.
    Citations: 22     Fields:    
  92. Irimia D, Toner M. Spontaneous migration of cancer cells under conditions of mechanical confinement. Integr Biol (Camb). 2009 Sep; 1(8-9):506-12. PMID: 20023765; PMCID: PMC3763902.
    Citations: 66     Fields:    Translation:HumansCells
  93. Russom A, Irimia D, Toner M. Chemical gradient-mediated melting curve analysis for genotyping of SNPs. Electrophoresis. 2009 Jul; 30(14):2536-43. PMID: 19593749; PMCID: PMC2784656.
    Citations:    Fields:    Translation:Cells
  94. Wang S, Chen PC, Berthiaume F, Toner M, Jayaraman A, Yarmush ML. Dynamic effect of heat shock pretreatment on apoptotic responses to TNF-alpha in liver cells. J Biomech Eng. 2009 Jul; 131(7):071003. PMID: 19640128.
    Citations:    Fields:    Translation:AnimalsCells
  95. Russom A, Gupta AK, Nagrath S, Di Carlo D, Edd JF, Toner M. Differential inertial focusing of particles in curved low-aspect-ratio microchannels. New J Phys. 2009 Jul 01; 11:75025. PMID: 20862272.
    Citations: 20     
  96. Irimia D, Balázsi G, Agrawal N, Toner M. Adaptive-control model for neutrophil orientation in the direction of chemical gradients. Biophys J. 2009 May 20; 96(10):3897-916. PMID: 19450463; PMCID: PMC2712156.
    Citations: 15     Fields:    Translation:HumansCells
  97. Elmoazzen HY, Lee GY, Li MW, McGinnis LK, Lloyd KC, Toner M, Biggers JD. Further optimization of mouse spermatozoa evaporative drying techniques. Cryobiology. 2009 Aug; 59(1):113-5. PMID: 19375415; PMCID: PMC2722843.
    Citations: 7     Fields:    Translation:AnimalsCells
  98. Saenz J, Toner M, Risco R. Comparison between ideal and nonideal solution models for single-cell cryopreservation protocols. J Phys Chem B. 2009 Apr 09; 113(14):4853-64. PMID: 19338369.
    Citations: 1     Fields:    Translation:AnimalsCells
  99. Edd JF, Humphry KJ, Irimia D, Weitz DA, Toner M. Nucleation and solidification in static arrays of monodisperse drops. Lab Chip. 2009 Jul 07; 9(13):1859-65. PMID: 19532960; PMCID: PMC4476639.
    Citations: 8     Fields:    Translation:Cells
  100. Hwang DK, Oakey J, Toner M, Arthur JA, Anseth KS, Lee S, Zeiger A, Van Vliet KJ, Doyle PS. Stop-flow lithography for the production of shape-evolving degradable microgel particles. J Am Chem Soc. 2009 Apr 01; 131(12):4499-504. PMID: 19215127; PMCID: PMC4040147.
    Citations: 14     Fields:    
  101. Sitaula R, Elmoazzen H, Toner M, Bhowmick S. Desiccation tolerance in bovine sperm: a study of the effect of intracellular sugars and the supplemental roles of an antioxidant and a chelator. Cryobiology. 2009 Jun; 58(3):322-30. PMID: 19318090.
    Citations: 2     Fields:    Translation:AnimalsCells
  102. Roach KL, King KR, Uygun K, Hand SC, Kohane IS, Yarmush ML, Toner M. High-throughput single cell arrays as a novel tool in biopreservation. Cryobiology. 2009 Jun; 58(3):315-21. PMID: 19303403; PMCID: PMC2717893.
    Citations: 4     Fields:    Translation:Cells
  103. Di Carlo D, Edd JF, Humphry KJ, Stone HA, Toner M. Particle segregation and dynamics in confined flows. Phys Rev Lett. 2009 Mar 06; 102(9):094503. PMID: 19392526; PMCID: PMC4485430.
    Citations: 45     Fields:    
  104. Sequist LV, Nagrath S, Toner M, Haber DA, Lynch TJ. The CTC-chip: an exciting new tool to detect circulating tumor cells in lung cancer patients. J Thorac Oncol. 2009 Mar; 4(3):281-3. PMID: 19247082; PMCID: PMC4486079.
    Citations: 35     Fields:    Translation:HumansCells
  105. Menze MA, Boswell L, Toner M, Hand SC. Occurrence of mitochondria-targeted Late Embryogenesis Abundant (LEA) gene in animals increases organelle resistance to water stress. J Biol Chem. 2009 Apr 17; 284(16):10714-9. PMID: 19228698; PMCID: PMC2667758.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  106. Cheng X, Gupta A, Chen C, Tompkins RG, Rodriguez W, Toner M. Enhancing the performance of a point-of-care CD4+ T-cell counting microchip through monocyte depletion for HIV/AIDS diagnostics. Lab Chip. 2009 May 21; 9(10):1357-64. PMID: 19417901; PMCID: PMC4064257.
    Citations: 23     Fields:    Translation:HumansCells
  107. Guillemette MD, Cui B, Roy E, Gauvin R, Giasson CJ, Esch MB, Carrier P, Deschambeault A, Dumoulin M, Toner M, Germain L, Veres T, Auger FA. Surface topography induces 3D self-orientation of cells and extracellular matrix resulting in improved tissue function. Integr Biol (Camb). 2009 Feb; 1(2):196-204. PMID: 20023803; PMCID: PMC4487987.
    Citations: 14     Fields:    Translation:HumansCells
  108. Kasuga K, Yang R, Porter TF, Agrawal N, Petasis NA, Irimia D, Toner M, Serhan CN. Rapid appearance of resolvin precursors in inflammatory exudates: novel mechanisms in resolution. J Immunol. 2008 Dec 15; 181(12):8677-87. PMID: 19050288; PMCID: PMC2664686.
    Citations: 107     Fields:    Translation:HumansAnimalsCells
  109. Moore RN, Dasgupta A, Rajaei N, Yarmush ML, Toner M, Larue L, Moghe PV. Enhanced differentiation of embryonic stem cells using co-cultivation with hepatocytes. Biotechnol Bioeng. 2008 Dec 15; 101(6):1332-43. PMID: 18571804; PMCID: PMC4492440.
    Citations: 10     Fields:    Translation:AnimalsCells
  110. Ergenc AF, Li MW, Toner M, Biggers JD, Lloyd KC, Olgac N. Rotationally oscillating drill (Ros-Drill) for mouse ICSI without using mercury. Mol Reprod Dev. 2008 Dec; 75(12):1744-51. PMID: 18437690; PMCID: PMC5006739.
    Citations: 1     Fields:    Translation:AnimalsCells
  111. Irimia D, Mindrinos M, Russom A, Xiao W, Wilhelmy J, Wang S, Heath JD, Kurn N, Tompkins RG, Davis RW, Toner M. Genome-wide transcriptome analysis of 150 cell samples. Integr Biol (Camb). 2009 Jan; 1(1):99-107. PMID: 20023796; PMCID: PMC3763906.
    Citations: 5     Fields:    
  112. Hsu CH, Di Carlo D, Chen C, Irimia D, Toner M. Microvortex for focusing, guiding and sorting of particles. Lab Chip. 2008 Dec; 8(12):2128-34. PMID: 19023476; PMCID: PMC4142319.
    Citations: 17     Fields:    
  113. Agrawal N, Toner M, Irimia D. Neutrophil migration assay from a drop of blood. Lab Chip. 2008 Dec; 8(12):2054-61. PMID: 19023468; PMCID: PMC3770894.
    Citations: 21     Fields:    Translation:HumansCells
  114. Eroglu A, Bailey SE, Toner M, Toth TL. Successful cryopreservation of mouse oocytes by using low concentrations of trehalose and dimethylsulfoxide. Biol Reprod. 2009 Jan; 80(1):70-8. PMID: 18815355; PMCID: PMC2804808.
    Citations: 19     Fields:    Translation:AnimalsCells
  115. Adams DR, Toner M, Langer R. Microflow and crack formation patterns in drying sessile droplets of liposomes suspended in trehalose solutions. Langmuir. 2008 Aug 05; 24(15):7688-97. PMID: 18613701.
    Citations: 4     Fields:    
  116. Maheswaran S, Sequist LV, Nagrath S, Ulkus L, Brannigan B, Collura CV, Inserra E, Diederichs S, Iafrate AJ, Bell DW, Digumarthy S, Muzikansky A, Irimia D, Settleman J, Tompkins RG, Lynch TJ, Toner M, Haber DA. Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med. 2008 Jul 24; 359(4):366-77. PMID: 18596266; PMCID: PMC3551471.
    Citations: 495     Fields:    Translation:HumansCells
  117. Edd JF, Di Carlo D, Humphry KJ, Köster S, Irimia D, Weitz DA, Toner M. Controlled encapsulation of single-cells into monodisperse picolitre drops. Lab Chip. 2008 Aug; 8(8):1262-4. PMID: 18651066; PMCID: PMC2570196.
    Citations: 70     Fields:    Translation:HumansCells
  118. Park K, Jang J, Irimia D, Sturgis J, Lee J, Robinson JP, Toner M, Bashir R. 'Living cantilever arrays' for characterization of mass of single live cells in fluids. Lab Chip. 2008 Jul; 8(7):1034-41. PMID: 18584076; PMCID: PMC3804646.
    Citations: 18     Fields:    Translation:HumansCells
  119. He X, Fowler A, Menze M, Hand S, Toner M. Desiccation kinetics and biothermodynamics of glass forming trehalose solutions in thin films. Ann Biomed Eng. 2008 Aug; 36(8):1428-39. PMID: 18500553.
    Citations:    Fields:    Translation:Cells
  120. Kelly RT, Tang K, Irimia D, Toner M, Smith RD. Elastomeric microchip electrospray emitter for stable cone-jet mode operation in the nanoflow regime. Anal Chem. 2008 May 15; 80(10):3824-31. PMID: 18419138; PMCID: PMC2692495.
    Citations: 16     Fields:    
  121. Parekkadan B, Berdichevsky Y, Irimia D, Leeder A, Yarmush G, Toner M, Levine JB, Yarmush ML. Cell-cell interaction modulates neuroectodermal specification of embryonic stem cells. Neurosci Lett. 2008 Jun 20; 438(2):190-5. PMID: 18467031; PMCID: PMC2448393.
    Citations: 17     Fields:    Translation:AnimalsCells
  122. He X, Park EY, Fowler A, Yarmush ML, Toner M. Vitrification by ultra-fast cooling at a low concentration of cryoprotectants in a quartz micro-capillary: a study using murine embryonic stem cells. Cryobiology. 2008 Jun; 56(3):223-32. PMID: 18462712; PMCID: PMC2728604.
    Citations: 21     Fields:    Translation:AnimalsCells
  123. Russom A, Sethu P, Irimia D, Mindrinos MN, Calvano SE, Garcia I, Finnerty C, Tannahill C, Abouhamze A, Wilhelmy J, López MC, Baker HV, Herndon DN, Lowry SF, Maier RV, Davis RW, Moldawer LL, Tompkins RG, Toner M. Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. Clin Chem. 2008 May; 54(5):891-900. PMID: 18375483; PMCID: PMC4011019.
    Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
  124. Di Carlo D, Edd JF, Irimia D, Tompkins RG, Toner M. Equilibrium separation and filtration of particles using differential inertial focusing. Anal Chem. 2008 Mar 15; 80(6):2204-11. PMID: 18275222.
    Citations: 55     Fields:    Translation:Cells
  125. Toner M, Tompkins RG. Invention, innovation, entrepreneurship in academic medical centers. Surgery. 2008 Feb; 143(2):168-71. PMID: 18242329; PMCID: PMC2408552.
    Citations: 3     Fields:    
  126. Park J, Li Y, Berthiaume F, Toner M, Yarmush ML, Tilles AW. Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates. Biotechnol Bioeng. 2008 Feb 01; 99(2):455-67. PMID: 17626294.
    Citations: 14     Fields:    Translation:AnimalsCells
  127. Nagrath S, Sequist LV, Maheswaran S, Bell DW, Irimia D, Ulkus L, Smith MR, Kwak EL, Digumarthy S, Muzikansky A, Ryan P, Balis UJ, Tompkins RG, Haber DA, Toner M. Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature. 2007 Dec 20; 450(7173):1235-9. PMID: 18097410; PMCID: PMC3090667.
    Citations: 750     Fields:    Translation:HumansCells
  128. King KR, Wang S, Jayaraman A, Yarmush ML, Toner M. Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments. Lab Chip. 2008 Jan; 8(1):107-16. PMID: 18094768.
    Citations: 26     Fields:    Translation:AnimalsCells
  129. Di Carlo D, Irimia D, Tompkins RG, Toner M. Continuous inertial focusing, ordering, and separation of particles in microchannels. Proc Natl Acad Sci U S A. 2007 Nov 27; 104(48):18892-7. PMID: 18025477; PMCID: PMC2141878.
    Citations: 149     Fields:    Translation:HumansCells
  130. Adams DR, Toner M, Langer R. Role of trehalose in prevention of giant vesicle adsorption and encapsulated solute leakage in anhydrobiotic preservation. Langmuir. 2007 Dec 18; 23(26):13013-23. PMID: 17983248.
    Citations: 4     Fields:    Translation:Cells
  131. Toner M. Development of new therapeutic applications using microfluidics. J Vis Exp. 2007; (8):323. PMID: 18989425; PMCID: PMC2562499.
    Citations:    Fields:    Translation:Humans
  132. Li MW, Biggers JD, Toner M, Griffey SM, Lloyd KC. Phenotypic analysis of C57BL/6J and FVB/NJ mice generated using evaporatively dried spermatozoa. Comp Med. 2007 Oct; 57(5):469-75. PMID: 17974129.
    Citations: 2     Fields:    Translation:AnimalsCells
  133. Kotz K, Cheng X, Toner M. Cell capture using a microfluidic device. J Vis Exp. 2007; (8):320. PMID: 18989424; PMCID: PMC2562498.
    Citations: 1     Fields:    Translation:HumansAnimals
  134. Kotz K, Cheng X, Toner M. PDMS device fabrication and surface modification. J Vis Exp. 2007; (8):319. PMID: 18989423; PMCID: PMC2561242.
    Citations: 4     Fields:    
  135. Parekkadan B, Sethu P, van Poll D, Yarmush ML, Toner M. Osmotic selection of human mesenchymal stem/progenitor cells from umbilical cord blood. Tissue Eng. 2007 Oct; 13(10):2465-73. PMID: 17665999.
    Citations: 7     Fields:    Translation:HumansCells
  136. Irimia D, Charras G, Agrawal N, Mitchison T, Toner M. Polar stimulation and constrained cell migration in microfluidic channels. Lab Chip. 2007 Dec; 7(12):1783-90. PMID: 18030401; PMCID: PMC3001245.
    Citations: 46     Fields:    Translation:HumansCells
  137. Risco R, Elmoazzen H, Doughty M, He X, Toner M. Thermal performance of quartz capillaries for vitrification. Cryobiology. 2007 Dec; 55(3):222-9. PMID: 17919532.
    Citations: 12     Fields:    
  138. Cheng X, Irimia D, Dixon M, Ziperstein JC, Demirci U, Zamir L, Tompkins RG, Toner M, Rodriguez WR. A microchip approach for practical label-free CD4+ T-cell counting of HIV-infected subjects in resource-poor settings. J Acquir Immune Defic Syndr. 2007 Jul 01; 45(3):257-61. PMID: 17414933.
    Citations: 33     Fields:    Translation:HumansCells
  139. Park J, Cho CH, Parashurama N, Li Y, Berthiaume F, Toner M, Tilles AW, Yarmush ML. Microfabrication-based modulation of embryonic stem cell differentiation. Lab Chip. 2007 Aug; 7(8):1018-28. PMID: 17653344.
    Citations: 35     Fields:    Translation:AnimalsCells
  140. Cheng X, Liu YS, Irimia D, Demirci U, Yang L, Zamir L, Rodríguez WR, Toner M, Bashir R. Cell detection and counting through cell lysate impedance spectroscopy in microfluidic devices. Lab Chip. 2007 Jun; 7(6):746-55. PMID: 17538717; PMCID: PMC4476634.
    Citations: 32     Fields:    Translation:HumansCells
  141. Cho CH, Park J, Nagrath D, Tilles AW, Berthiaume F, Toner M, Yarmush ML. Oxygen uptake rates and liver-specific functions of hepatocyte and 3T3 fibroblast co-cultures. Biotechnol Bioeng. 2007 May 01; 97(1):188-99. PMID: 17054120.
    Citations: 24     Fields:    Translation:AnimalsCells
  142. Li MW, Biggers JD, Elmoazzen HY, Toner M, McGinnis L, Lloyd KC. Long-term storage of mouse spermatozoa after evaporative drying. Reproduction. 2007 May; 133(5):919-29. PMID: 17616722.
    Citations: 15     Fields:    Translation:AnimalsCells